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The association between statin use and diabetic nephropathy in US adults: data from NHANES 2005 - 2018.
The association between statin use and diabetic nephropathy in US adults: data from NHANES 2005 - 2018.
Fuente:Frontiers in Endocrinology
Extracto:
Taking statins
long-term increases the risk of DN. Statin use is associated with an increased
risk of DN. Caution should be exercised when prescribing atorvastatin and
simvastatin for long-term statin therapy.
Claves:NHANES, association, diabetes, diabetic nephropathy, statin use
institución:(a) Medical School, Hunan University of Chinese Medicine, Changsha, Hunan, China. (b) Medical School, Hunan University of Chinese Medicine, Changsha, Hunan, China.
Conflicto:The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
Low TSH and low T3 hormone levels as a prognostic for mortality in COVID-19 intensive care patients.
Low TSH and low T3 hormone levels as a prognostic for mortality in COVID-19 intensive care patients.
Fuente:Frontiers in Endocrinology
Extracto:
Low serum thyroid hormone levels-T3, T4, and TSH-in COVID-19 ICU
patients are associated with higher mortality and could possibly be used as a
prognostic factor for mortality among COVID-19 ICU patients. Thyroid hormone
levels should be a part in the routine evaluation of COVID-19 ICU patients.
Claves:COVID-19, T3, TSH, intensive care unit, mortality, thyroid hormones
institución:(a) Azrieli Faculty of Medicine, Bar-Ilan University, Safed, Israel. (b) Department of ENT, Ziv Medical Center, Safed, Israel.
Conflicto:The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
The unique association between the level of plateletcrit and the prevalence of diabetic kidney disease: a cross-sectional study.
The unique association between the level of plateletcrit and the prevalence of diabetic kidney disease: a cross-sectional study.
Fuente:Frontiers in Endocrinology
Extracto:
PCT demonstrates a weak diagnostic value for T2DM patients
at risk of developing DKD and experiencing proteinuria, and PLT shows a similarly
modest diagnostic utility for detecting proteinuria. These insights contribute to
a deeper understanding of the complex dynamics involved in DKD. Additionally,
incorporating these markers into routine clinical assessments could enhance risk
stratification, facilitating early interventions and personalized management
strategies.
institución:(a) Department of Endocrinology, Guang'anmen Hospital, China Academy of Chinese Medical Sciences, Beijing, China. (b) Beijing University of Chinese Medicine, Beijing, China.
Conflicto:The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
Association between monocyte to lymphocyte ratio and diabetic foot ulcer in the population of the US with diabetes based on the 1999-2004 National Health and Nutrition Examination Survey data: a retrospective cross-sectional study.
Association between monocyte to lymphocyte ratio and diabetic foot ulcer in the population of the US with diabetes based on the 1999-2004 National Health and Nutrition Examination Survey data: a retrospective cross-sectional study.
Fuente:Frontiers in Endocrinology
Extracto:
MLR is significantly associated with DFU in diabetes patients,
and can be used as one of the indicators for predicting the occurrence of DFU.
MLR assessment may be a valuable component in the follow-up of patients with
diabetes.
Claves:diabetic foot ulcer, NHANES, diabetes, inflammation, monocyte-lymphocyte ratio
institución:(a) Department of Burns and Plastic Surgery, Affiliated Hospital of Zunyi Medical University, Zunyi, Guizhou, China. (b) Department of Burns and Plastic Surgery, Affiliated Hospital of Zunyi Medical University, Zunyi, Guizhou, China.
Conflicto:The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
Liver histology is associated with long-term clinical outcomes in patients with metabolic dysfunction-associated steatohepatitis.
Liver histology is associated with long-term clinical outcomes in patients with metabolic dysfunction-associated steatohepatitis.
Fuente:Hepatology Communications
Extracto:
Fibrosis stage and lobular
inflammation and hepatocyte ballooning grades predict the risk of long-term
outcomes, supporting the use of these histological features as potential
surrogate markers of disease progression or clinical outcomes.
Cita:Hepatol Commun 2024 Jun 1; 8 (6)
Autor/es:Younossi, Zobair M (a) Mangla, Kamal Kant (b)
institución:(a) Beatty Liver and Obesity Research Program, Inova Health System, Falls Church, Virginia, USA. (b) The Global NASH Council, Washington, District of Columbia, USA.
Conflicto:Zobair M. Younossi has received research funding and/or consultancy fees from Abbott, AstraZeneca, Bristol-Myers Squib, Gilead Sciences, Intercept, Madrigal, Merck, Novo Nordisk A/S, Boehringer Ingelheim, Cymabay, GlaxoSmithKline, and Siemens. Kamal Kant Mangla, Tina Landsvig Berentzen, Katrine Grau, Mette Skalshøi Kjær, Louise Maymann Nitze, and Steen Ladelund are employees of (and/or hold shares in) Novo Nordisk. Crystal Coolbaugh and Chih-Yuan Hsu...
su are employees of Nashville Biosciences. Hannes Hagström’s institutions have received research funding from AstraZeneca, EchoSens, Gilead, Intercept, MSD, and Pfizer. He has served as a consultant for AstraZeneca and has been part of hepatic events adjudication committees for KOWA and GW Pharma. No remuneration was received by any author for the development of this manuscript.
Rifaximin plus lactulose versus lactulose alone for reducing the risk of HE recurrence.
Rifaximin plus lactulose versus lactulose alone for reducing the risk of HE recurrence.
Fuente:Hepatology Communications
Tipo de trabajo:Estudio abierto
Extracto:
Rifaximin plus lactulose was more efficacious than lactulose alone for reducing
the risk of overt HE recurrence and HE-related hospitalization in adults grouped
by select baseline disease characteristics.
Cita:Hepatol Commun 2024 Jun 1; 8 (6)
Autor/es:Sanyal, Arun J (a) Kowdley, Kris V (b)
institución:(a) Division of Gastroenterology, Hepatology, and Nutrition, Virginia Commonwealth University, Richmond, Virginia, USA. (b) Department of Gastroenterology and Hepatology, Elson Floyd College of Medicine, Spokane, Washington, USA.
Conflicto:Arun J. Sanyal consults and received grants from Boehringer Ingelheim, Bristol Myers Squibb, Eli Lilly, Gilead, Intercept, Inventiva, Madrigal, Mallinckrodt, Merck, Novartis, Novo Nordisk, and Pfizer. He consults and owns stock in GENFIT and HemoShear. He consults for 89bio, Albireo, Alnylam, Amgen, AstraZeneca, Covance, Genentech, HistoIndex, Janssen, NGM Bio, PathAI, Poxel, ProSciento, Regeneron, Roche, Salix, Siemens, and Terns. He received...
grants from Fractyl. He owns stock in Durect, Exhalenz, Indalo, NorthSea, Rivus, and Tiziana. He receives royalties from Elsevier and UpToDate. Kris V. Kowdley consults, is on the speakers' bureau, and received grants from Gilead and Intercept. He consults and received grants from 89bio, CymaBay, GENFIT, Madrigal, Mirum, NGM, and Pfizer. He consults and owns stock in Inipharm. He consults for Enanta, HighTide, and Salix. He is on speakers' bureau for AbbVie. He received grants from Corcept, GlaxoSmithKline, Hanmi, Novo Nordisk, Pliant, Terns, and Viking. Nancy S. Reau consults for AbbVie, Gilead, Intercept, and Salix. She received grants from Eiger. Nikolaos T. Pyrsopoulos consults for Salix. Christopher Allen is employed by Salix. Zeev Heimanson is employed by Salix. Jasmohan S. Bajaj consults for Merz. He received grant from Cosmo, Grifols, Mallinckrodt, Salix, and Sequana Medical.
Long-Term Effect of Home Blood Pressure Self-Monitoring Plus Medication Self-Titration for Patients With Hypertension
Long-Term Effect of Home Blood Pressure Self-Monitoring Plus Medication Self-Titration for Patients With Hypertension
Fuente:Jama Network Open
Tipo de trabajo:Estudio clínico aleatorizado
Extracto:
AND RELEVANCE: In this secondary analysis of a randomized clinical
trial, BP self-monitoring plus self-titration of antihypertensive medication
based on an individualized prearranged plan used in primary care reduced BP in
the longer term with passive follow-up compared with usual care, without
increasing health care use or adverse events. These results suggest that simple,
inexpensive, and easy-to-implement self-management interventions have the
potential to improve the long-term control of hypertension in routine clinical
practice. TRIAL REGISTRATION: ClinicalTrials.gov Identifier: NCT03242785.
institución:(a) Health Services Research & Pharmacoepidemiology Unit, Fundació per al Foment de la Investigació Sanitària i Biomèdica de la Comunitat Valenciana (Fisabio), Valencia, Spain. (b) Network for Research on Chronicity, Primary Care, and Health Promotion (RICAPPS), Spain.
Conflicto:Conflict of Interest Disclosures: Drs García-Sempere, Peiró, Hurtado, Rodríguez-Bernal, and Sanfélix-Gimeno and Mrs Robles-Cabaniñas reported receiving grants from RTI Health Solutions (contract between Fisabio and RTI Health Solutions) outside the submitted work. Dr Peiró reported receiving personal fees from GSK and MSD outside the submitted work. Dr Sanfélix-Gimeno reported receiving personal fees from MSD outside the submitted work. No other...
o other disclosures were reported.
Mode of delivery and birth outcomes before and during COVID-19 -A population-based study in Ontario, Canada.
Mode of delivery and birth outcomes before and during COVID-19 -A population-based study in Ontario, Canada.
Fuente:Plos One
Extracto:
Ensuring ongoing
prenatal care during the pandemic may reduce risks of adverse mode of delivery
and the need for acute care during pregnancy.
Cita:PLoS One 2024; 19 (5) : e0303175.
Autor/es:To, Teresa (a) Zhu, Jingqin (b)
institución:(a) Dalla Lana School of Public Health, University of Toronto, Toronto, Ontario, Canada. (b) Child Health Evaluative Sciences, The Hospital for Sick Children, Toronto, Ontario, Canada.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Digital interventions for self-management of prediabetes
Digital interventions for self-management of prediabetes
Fuente:Plos One
Tipo de trabajo:Revisión
Extracto:
Whilst the evidence here suggests that digital
interventions to support prediabetes self-management are acceptable and have the
potential to reduce one's risk of progression to type 2 diabetes, more research
is needed to understand which interventions, and which components specifically,
have the greatest reach to diverse populations, are most effective at promoting
user engagement, and are most effective in the longer term.
Cita:PLoS One 2024; 19 (5) : e0303074.
Autor/es:Stowell, Melanie (a) Dobson, Rosie (b)
institución:(a) National Institute for Health Innovation, University of Auckland, Auckland, New Zealand. (b) National Institute for Health Innovation, University of Auckland, Auckland, New Zealand.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Ethnobotanical survey of medicinal plants used by various ethnic tribes of Mizoram, India.
Ethnobotanical survey of medicinal plants used by various ethnic tribes of Mizoram, India.
Fuente:Plos One
Extracto:
The therapeutic applications of documented plants provide fundamental
information for additional studies centered on pharmacological investigations and
the preservation of the most significant species.
Cita:PLoS One 2024; 19 (5) : e0302792.
Autor/es:Ralte, Laldinfeli (a) Singh, Y Tunginba (b)
institución:(a) Department of Botany, Laboratory of Molecular Ecology & Genetics, Mizoram University, Aizawl, Mizoram, India. (b) Department of Botany, Laboratory of Molecular Ecology & Genetics, Mizoram University, Aizawl, Mizoram, India.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Therapies go digital. What drives physicians' acceptance?
Therapies go digital. What drives physicians' acceptance?
Fuente:Plos One
Extracto:
The results highlight practical implications for healthcare institutions
and Digital Therapeutics manufacturers willing to promote their adoption.
institución:(a) Department of Management Engineering, Politecnico di Milano, Milano, Italy. (b) Department of Management Engineering, Politecnico di Milano, Milano, Italy.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Prevalence and associated factors of proliferative diabetic retinopathy among adult diabetic patients in Northwest Ethiopia, 2023: A cross-sectional multicenter study.
Prevalence and associated factors of proliferative diabetic retinopathy among adult diabetic patients in Northwest Ethiopia, 2023: A cross-sectional multicenter study.
Fuente:Plos One
Extracto:
The prevalence of proliferative diabetic
retinopathy among adult diabetic patients in the diabetes clinic was higher than
the global study. Hypertension, peripheral neuropathy, nephropathy, ≥10 year's
duration of diabetic mellitus, insulin use and poor adherence to diabetes
mellitus medications were among the factors significantly associated with
proliferative diabetic retinopathy.
institución:(a) Department of Optometry, College of Medicine and Health Sciences, Comprehensive Specialized Hospital, University of Gondar, Gondar, Ethiopia. (b) Department of Optometry, College of Medicine and Health Sciences, Comprehensive Specialized Hospital, University of Gondar, Gondar, Ethiopia.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Glucose levels measured with continuous glucose monitoring in uncomplicated pregnancies.
Glucose levels measured with continuous glucose monitoring in uncomplicated pregnancies.
Fuente:Bmj Open Diabetes Research & Care
Extracto:
Mean glucose levels and time 63-120 mg/dL (3.5-6.7 mmol/L) remained
nearly stable throughout pregnancy and values above 140 mg/dL (7.8 mmol/L) were
rare. Mean glucose levels in pregnancy trend higher as BMI increases into the
overweight/obesity range. The glycemic metrics reported during uncomplicated
pregnancies represent treatment targets for pregnant individuals.
Claves:Pregnancy, Reproductive Health, Research
Cita:BMJ Open Diabetes Res Care 2024 May 10; 12 (3)
Autor/es:Carlson, Anders L (a) Beck, Roy W (b)
institución:(a) International Diabetes Center Park Nicollet, St. Louis Park, Minnesota, USA. (b) Jaeb Center for Health Research, Tampa, Florida, USA.
Conflicto:Competing interests: ALC reports no personal financial disclosures but reports that his institution has received funding on his behalf as follows: research support from Medtronic, Tandem, Insulet, Abbott, Dexcom, Eli Lilly, NovoNordisk, Sanofi and UnitedHealth Group and consultancy fees from Mannkind and NovoNordisk. RWB reports no personal financial disclosures but reports that his institution has received funding on his behalf...
as follows: grant funding and study supplies from Dexcom. RMB has received research support, has acted as a consultant, or has been on the scientific advisory board for Abbott Diabetes Care, Ascensia, Bigfoot Biomedical, CeQur, Dexcom, Eli Lilly, Embecta, Hygieia, Insulet, Medtronic, Novo Nordisk, Onduo, Roche Diabetes Care, Tandem Diabetes Care, Sanofi, UnitedHealthcare, Vertex Pharmaceuticals and Zealand Pharma. RMB’s employer, non-profit HealthPartners Institute, contracts for his services and he receives no personal income for any of these activities. CD reports advisory work for Dexcom for GDM patient-facing materials and system implementation.
Prevalence of hypertension and diabetes mellitus in Peruvian patients with chronic kidney disease
Prevalence of hypertension and diabetes mellitus in Peruvian patients with chronic kidney disease
Fuente:Bmc Nephrology
Tipo de trabajo:Revisión sistemática
Extracto:
Approximately
one-third of Peruvian patients with CKD have HTN and DM. These findings highlight
the importance of implementing prevention and control measures for these chronic
noncommunicable diseases in the Peruvian population, such as promoting healthy
lifestyles, encouraging early detection and proper management of hypertension and
diabetes, and improving access to medical care and health services.
Claves:Chronic kidney disease, Diabetes mellitus, Hypertension, Peru
Cita:BMC Nephrol 2024 May 10; 25 (1) : 160.
Autor/es:León-Figueroa, Darwin A (a) Aguirre-Milachay, Edwin (b)
institución:(a) Facultad de Medicina Humana, Universidad de San Martín de Porres, Chiclayo, 15011, Peru. (b) Facultad de Medicina Humana, Universidad de San Martín de Porres, Chiclayo, 15011, Peru.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Patients as teachers: a within-subjects randomized pilot experiment of patient-led online learning modules for health professionals.
Patients as teachers: a within-subjects randomized pilot experiment of patient-led online learning modules for health professionals.
Fuente:Bmc Medical Education
Extracto:
DISCUSSION: Findings from this
experiment suggest that learners can learn to provide better patient-centered
care by watching patient-led online learning modules created in collaboration
with a diversity of patient partners.
institución:(a) Université de Sherbrooke, Sherbrooke, Canada. (b) Université Laval, Québec City, Canada.
Conflicto:RN held a fellowship from Diabetes Action Canada. Expert patients who appeared in the module videos used in the intervention or contributed as co-authors are also members of Diabetes Action Canada. These patients were informed that participation in this study was independent from their other participation in Diabetes Action Canada and that if they preferred not to participate, the decision...
would have no impact on their participation in Diabetes Action Canada. Patient partners were not compensated for their participation in the video recording. Patient partners were offered compensation for time spent reviewing and commenting on the findings of this study. All other authors have no competing interest to declare.
Association between HDL cholesterol with diabetic retinopathy in diabetic patients: a cross-sectional retrospective study.
Association between HDL cholesterol with diabetic retinopathy in diabetic patients: a cross-sectional retrospective study.
Fuente:Bmc Endocrine Disorders
Extracto:
Our study revealed an inverted U-shaped
positive relationship between HDL-C and DR.The findings may provide us with a
more comprehensive understanding of the association between HDL-C and DR.
institución:(a) Department of Ophthalmology, The First People's Hospital of Jiangyin District, Wuxi, Jiangsu, 214400, People's Republic of China. 17361750772@163.com. (b) Department of Ophthalmology, The First People's Hospital of Jiangyin District, Wuxi, Jiangsu, 214400, People's Republic of China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Clinical characteristics of pyogenic liver abscess with and without biliary surgery history: a retrospective single-center experience.
Clinical characteristics of pyogenic liver abscess with and without biliary surgery history: a retrospective single-center experience.
Fuente:Bmc Infectious Diseases
Extracto:
Patients with
BS history, especially those who have undergone BEA, have an increased
susceptibility to PLA formation without affecting prognosis.
institución:(a) Department of Hepatobiliary Surgery, Shaanxi Provincial People's Hospital, 256 West Youyi Road, Xi'an, Shaanxi Province, 710068, China. (b) Shanghai Institute of Hematology, State Key Laboratory of Medical Genomics, National Research Center for Translational Medicine at Shanghai, Ruijin Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, 197 Rui Jin Er Road, Shanghai, 200025, China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Interactions between host and gut microbiota in gestational diabetes mellitus and their impacts on offspring.
Interactions between host and gut microbiota in gestational diabetes mellitus and their impacts on offspring.
Fuente:Bmc Microbiology
Extracto:
Finally, we compared offspring microbiota
composition from GDM with that from normal pregnancies, and described the
possible mechanism.
Claves:Gestational diabetes mellitus (GDM), Gut microbiota, Host-microbiome interactions, Metabolism, Offspring
Cita:BMC Microbiol 2024 May 10; 24 (1) : 161.
Autor/es:Wang, Shuxian (a) Cui, Zifeng (b)
institución:(a) Department of Obstetrics and Gynaecology, Peking University First Hospital, Beijing, China. (b) Beijing Key Laboratory of Maternal Fetal Medicine of Gestational Diabetes Mellitus, Beijing, China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Comparison of a portable, pneumotach flow-sensor-based spirometer (Spirofy™) with the vitalograph alpha Touch™ spirometer in evaluating lung function in healthy individuals, asthmatics, and COPD patients-a randomized, crossover study.
Comparison of a portable, pneumotach flow-sensor-based spirometer (Spirofy™) with the vitalograph alpha Touch™ spirometer in evaluating lung function in healthy individuals, asthmatics, and COPD patients-a randomized, crossover study.
Fuente:Bmc Pulmonary Medicine
Tipo de trabajo:Estudio abierto
Extracto:
Spirofy™ is a portable and easy-to-use device and
is as accurate as the standard Vitalograph Alpha Touch™ spirometer for the
diagnosis of COPD and asthma. TRIAL REGISTRATION: CTRI/2021/09/036492 (Clinical
Trials Registry - India).
institución:(a) Department of Pulmonology, Pulmonary Sleep & Critical Care, Metro Centre for Respiratory Diseases, WASOG Sarcoid Clinic, Noida, Uttar Pradesh, India. (b) Department of Pulmonology, Chest & Diabetes Research Institute, Chennai, Tamil Nadu, India.
Conflicto:Dr. Meena Lopez, Dr. Rushika Shah, Abhijit Vaidya, Nandan Kulkarni, Dr. Sandesh Sawant, and Dr. Jaideep Gogtay are employees of Cipla Ltd. All other authors do not possess any competing interest.
Dependency and frailty in the older haemodialysis patient.
Dependency and frailty in the older haemodialysis patient.
Fuente:Bmc Geriatrics
Extracto:
The older adult cohort, averaging over four years on
hemodialysis, exhibited high rates of comorbidity, frailty, and dependency,
necessitating substantial support in transport and living arrangements. A third
of these patients lacked residual urine output, yet their dialysis regimen
mirrored those with preserved output. The study underscores the imperative for
tailored therapeutic strategies to mitigate dependency, preserve residual renal
function, and alleviate post-dialysis fatigue, ultimately enhancing the physical
quality of life for these patients.