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The increasing number of Open Access articles widens the reading offer
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SIIC created, produced and handles the AFT software that deciphers
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Altered RBC deformability in diabetes: clinical characteristics and RBC pathophysiology.
Altered RBC deformability in diabetes: clinical characteristics and RBC pathophysiology.
Fuente:Cardiovascular Diabetology
Tipo de trabajo:Estudio clínico
Extracto:
Findings suggest impaired RBCD incurs
similar demographic and clinical risk factors as diabetic vascular disease, with
early pathophysiological RBC changes indicative of disordered RBC hydration in
diabetes. Findings provide strong evidence for disordered oxygen release as a
functional consequence of reduced RBCD. CLINICAL TRIAL NUMBER: NCT00071526.
Cita:Cardiovasc Diabetol 2024 Oct 18; 23 (1) : 370.
institución:(a) Molecular and Clinical Nutrition Section, Digestive Diseases Branch, Intramural Research Program, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD, 20892, USA. Ebenuwaic@nih.gov. (b) Molecular and Clinical Nutrition Section, Digestive Diseases Branch, Intramural Research Program, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD, 20892, USA.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Impact of physical activity levels on the association between air pollution exposures and glycemic indicators in older individuals.
Impact of physical activity levels on the association between air pollution exposures and glycemic indicators in older individuals.
Fuente:Environmental Health a Global Access Science Source
Tipo de trabajo:Estudio de cohortes
Extracto:
We demonstrated
longitudinal associations between air pollution exposures and increased insulin
resistance in older individuals. Maintaining moderate-to-vigorous physical
activity may mitigate the adverse effects of air pollution on insulin resistance.
In older individuals dwelling in highly polluted areas, an increase of less than
12,000 METs-min/week may be beneficial for insulin resistance.
institución:(a) Department of Public Health, Graduate School, Yonsei University, Seoul, Republic of Korea. (b) Department of Cancer Control and Population Health, Graduate School of Cancer Science and Policy, National Cancer Center, Goyang, Republic of Korea.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Diurnal patterns of accelerometer-measured physical activity and sleep and risk of all-cause mortality: a follow-up of the National Health and Nutrition Examination Surveys (NHANES).
Diurnal patterns of accelerometer-measured physical activity and sleep and risk of all-cause mortality: a follow-up of the National Health and Nutrition Examination Surveys (NHANES).
Fuente:The International Journal of Behavioral Nutrition and Physical Activity
Tipo de trabajo:Estudio de cohortes
Extracto:
Wearable activity-rest monitoring
data showed that peak physical activity in the early morning and irregular sleep
diurnal patterns are associated with increased mortality risk, and the
combination of these patterns further exaggerated the risk. Public health program
should acknowledge that the diurnal patterns of physical activity and sleep, in
addition to their duration and frequency, may play a crucial role in
lifestyle-based health promotion and management strategies.
Claves:All-cause mortality, Diurnal patterns, Physical activity, Sleep, Time of lifestyle behaviour
institución:(a) School of Public Health, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, 310058, Zhejiang, China. (b) The Key Laboratory of Intelligent Preventive Medicine of Zhejiang Province, Hangzhou, China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Screening for comorbid autoimmune disease should be considered in children with ANA positive juvenile idiopathic arthritis - results from the south-Swedish juvenile idiopathic arthritis cohort.
Screening for comorbid autoimmune disease should be considered in children with ANA positive juvenile idiopathic arthritis - results from the south-Swedish juvenile idiopathic arthritis cohort.
Fuente:Pediatric Rheumatology Online Journal
Tipo de trabajo:Consenso
Extracto:
Individuals with JIA have a significantly increased risk of being
diagnosed with an autoimmune condition after receiving their JIA diagnosis
compared to matched references. ANA positivity is associated with a further
increased risk. Our results emphasize awareness in physicians of additional
autoimmune disorders in individuals with JIA and advocate serological screening
of autoimmune conditions during follow-up.
Interpretable subgroup learning-based modeling framework: Study of diabetic kidney disease prediction.
Interpretable subgroup learning-based modeling framework: Study of diabetic kidney disease prediction.
Fuente:Health Informatics Journal
Extracto:
The iSLIM surpasses traditional global model in
predictive performance and subgroup-specific risk factor interpretation,
enhancing the understanding of DKD's heterogeneous mechanisms and potentially
increasing the adoption of machine learning models in clinical decision-making.
Claves:clinical decision support system, diabetic kidney disease, electronic health record, predictive modeling, subgroup learning
institución:(a) Big Data Decision Institute, Jinan University, Guangzhou, China. RINGGOLD: 47885 (b) School of Management, Jinan University, Guangzhou, China. RINGGOLD: 47885
Conflicto:Declaration of conflicting interestsThe author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.
Maternal and neonatal outcomes of congenital syphilis at a tertiary care center in Turkey; a retrospective observational study.
Maternal and neonatal outcomes of congenital syphilis at a tertiary care center in Turkey; a retrospective observational study.
Fuente:Journal of Obstetrics and Gynaecology The Journal of The Institute of Obstetrics and Gynaecology
Extracto:
Delayed diagnosis and inadequate treatment of MS can lead to
significant maternal and neonatal morbidity and mortality. Well-planned antenatal
care services should be provided for all expectant mothers in order to reduce
these adverse outcomes.
institución:(a) Department of Perinathology, Antalya Training and Research Hospital, Antalya, Turkey. (b) Department of Perinathology, Antalya Training and Research Hospital, Antalya, Turkey.
Influence of maternal health status during pregnancy and the child´s medical history on molar-incisor hypomineralization in a group of Spanish children (aged 6-14 years): a retrospective case-control study.
Influence of maternal health status during pregnancy and the child´s medical history on molar-incisor hypomineralization in a group of Spanish children (aged 6-14 years): a retrospective case-control study.
Fuente:Bmc Oral Health
Extracto:
Although there are different factors that may have statistically
significant relationships with MIH, they cannot be predicted. Therefore,
longitudinal studies, with a large sample size, are needed to determine the
influence of prenatal and postnatal factors on the prevalence and severity of MIH
in children.
Autor/es:Muñoz, Johanna (a) Alvarado-Lorenzo, Alfonso (b)
institución:(a) Department of Surgery, Faculty of Medicine, University of Salamanca, Salamanca, Spain. (b) Department of Surgery, Faculty of Medicine, University of Salamanca, Salamanca, Spain.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Association between total functional tooth unit score and hemoglobin A1c levels in Japanese community-dwelling individuals: the Nagasaki Islands study.
Association between total functional tooth unit score and hemoglobin A1c levels in Japanese community-dwelling individuals: the Nagasaki Islands study.
Fuente:Bmc Oral Health
Extracto:
In this community-based cross-sectional study, total FTU was
significantly associated with HbA1c levels, independent of other risk factors.
This suggests that reconstructed occlusal support areas, including dentures, are
associated with glycemic control in the older population.
Claves:Epidemiology, Functional tooth units, Hemoglobin A1c, Masticatory function
institución:(a) Department of Periodontology and Endodontology, Nagasaki University Graduate School of Biomedical Sciences, 1-7-1 Sakamoto, Nagasaki, 852-8588, Japan. (b) Department of Oral Health, Nagasaki University Graduate School of Biomedical Sciences, 1-7-1 Sakamoto, Nagasaki, 852-8588, Japan.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Analyzing missingness patterns in real-world data using the SMDI toolkit: application to a linked EHR-claims pharmacoepidemiology study.
Analyzing missingness patterns in real-world data using the SMDI toolkit: application to a linked EHR-claims pharmacoepidemiology study.
Fuente:Bmc Medical Research Methodology
Extracto:
We were able to
demonstrate the practical application of the SMDI toolkit in a real-world
setting. Application of the SMDI toolkit and the resulting insights of potential
missingness patterns can inform the choice of appropriate analytic methods and
increase transparency of research methods in handling missing data. This type of
approach can inform analytic decision making and may increase our ability to
generate evidence from real-world data.
Claves:Electronic health records, Missing data, Real-world evidence
Cita:BMC Med Res Methodol 2024 Oct 19; 24 (1) : 246.
Autor/es:Raman, Sudha R (a) Hammill, Bradley G (b)
institución:(a) Department of Population Health Sciences, Duke University School of Medicine, Durham, USA. Sudha.raman@duke.edu. (b) Department of Population Health Sciences, Duke University School of Medicine, Durham, USA.
Conflicto:The US Food and Drug Administration (FDA) approved the study protocol, statistical analysis plan and reviewed and approved this manuscript. Coauthors from the FDA participated in the results interpretation and in the preparation and decision to submit the manuscript for publication. The FDA had no role in data collection, management, or analysis. Janick Weberpals reports prior employment by Hoffmann-La Roche...
and previously held shares in Hoffmann-La Roche. Pamela Shaw is a named inventor on a patent licensed to Novartis by the University of Pennsylvania for an unrelated project. Sengwee Toh serves as a consultant for Pfizer, Inc. and TriNetX, LLC. on unrelated projects. Robert J Glynn has received research funding through his employer from Amarin, Kowa, Novartis, and Pfizer. Dr. Desai reports serving as Principal Investigator on investigator-initiated grants to the Brigham and Women’s Hospital from Novartis, Vertex, and Bristol-Myers-Squibb on unrelated projects. All remaining authors report no disclosures or conflicts of interest.
Lipid metabolism and hearing loss: association of non-high-density lipoprotein cholesterol to high-density lipoprotein cholesterol ratio (NHHR) with adolescent hearing health.
Lipid metabolism and hearing loss: association of non-high-density lipoprotein cholesterol to high-density lipoprotein cholesterol ratio (NHHR) with adolescent hearing health.
Fuente:Lipids in Health and Disease
Extracto:
NHHR is a promising biomarker for predicting adolescent
hearing threshold shifts and hearing loss. The study highlights the importance of
early lipid monitoring and management as strategies to prevent or reduce hearing
impairment.
institución:(a) Department of Otolaryngology-Head and Neck Surgery, Beijing Friendship Hospital, Capital Medical University, No.95, Yong'an Road, Xicheng District, Beijing, 100050, China. tsulinhjm@gmail.com. (b) Clinical Center for Hearing Loss, Capital Medical University, Beijing, 100050, China. tsulinhjm@gmail.com.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Weight loss, changes in body composition and inflammatory status after a very low-energy ketogenic therapy (VLEKT): does gender matter?
Weight loss, changes in body composition and inflammatory status after a very low-energy ketogenic therapy (VLEKT): does gender matter?
Fuente:Journal of Translational Medicine
Extracto:
These findings underscore the importance of considering sex-specific responses in
personalized obesity treatment strategies, particularly dietary interventions
like VLEKTs.
Claves:Body composition, Gender, Ketogenic diet, Nutrition, Obesity, Sex, VLCKD, Very Low-Energy Ketogenic Therapy (VLEKT), Very low-calorie ketogenic diet, Weight loss
institución:(a) Diabetologia e Andrologia, Dipartimento di Medicina Clinica e Chirurgia, Unità di Endocrinologia, Università Degli Studi di Napoli Federico II, Via Sergio Pansini 5, 80131, Naples, Italy. (b) Centro Italiano per la cura e il Benessere del Paziente con Obesità (C.I.B.O), Diabetologia e Andrologia, Dipartimento di Medicina Clinica e Chirurgia, Unità di Endocrinologia, Università Degli Studi di Napoli Federico II, Via Sergio Pansini 5, 80131, Naples, Italy.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
institución:(a) ALS/MND Unit, Hospital Universitari de Bellvitge, L'Hospitalet del Llobregat, Barcelona, Spain. (b) Neurology Department, Consorci Sanitari Alt Penedès-Garraf, Vilafranca del Penedès, Barcelona, Spain.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Drain versus no-drain at the donor sites of iliac crest bone graft: a retrospective study.
Drain versus no-drain at the donor sites of iliac crest bone graft: a retrospective study.
Fuente:Journal of Orthopaedic Surgery and Research
Extracto:
The
closed suction drainage should not be recommended routinely for iliac crest bone
graft patients. Only when the patient is at high risk for infection and without
severe blood loss, placing a single drainage tube is recommended. TRIAL
REGISTRATION: This study was registered at (NCT04807062) and approved by the
Ethics Committee of the participating institution (Theoretical No. 2015-003-1).
Claves:Blood loss, Close suction drainage, Iliac crest bone graft, Incision complications, Treatment
Cita:J Orthop Surg Res 2024 Oct 21; 19 (1) : 675.
Autor/es:Li, Yiran (a) Yang, Shuo (b)
institución:(a) Department of Orthopaedic, The Third Hospital of Hebei Medical University, Shijiazhuang, China. (b) Orthopaedic Research Institute of Hebei Province, Shijiazhuang, Hebei, China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
A Nomogram for Predicting Cancer-Associated Venous Thromboembolism in Hospitalized Patients Receiving Chemoradiotherapy for Cancer.
A Nomogram for Predicting Cancer-Associated Venous Thromboembolism in Hospitalized Patients Receiving Chemoradiotherapy for Cancer.
Fuente:Cancer Control Journal of The Moffitt Cancer Center
Extracto:
The incidence of CAT was relatively high among patients with cancer
receiving chemoradiotherapy. The nomogram risk model developed in this study has
good prediction efficiency and can provide a reference for the clinical
evaluation of the risk of adverse outcomes in patients with cancer receiving
chemoradiotherapy.
Cita:Cancer Control 2024 Jan-Dec; 31 : 10732748241290767.
Autor/es:Sisi, Yan (a) Genpeng, Li (b)
institución:(a) Radiation Oncology Center, Chongqing University Cancer Hospital, Chongqing, China. RINGGOLD: 605425 (b) Division of thyroid and parathyroid surgery, department of General Surgery, West China Hospital, Sichuan University, Chengdu, China.
Conflicto:Declaration of conflicting interestsThe author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.
Knowledge, attitudes, and practices regarding diabetic retinopathy among patients with diabetes in Dongola, Northern State, Sudan, 2022: a cross-sectional study.
Knowledge, attitudes, and practices regarding diabetic retinopathy among patients with diabetes in Dongola, Northern State, Sudan, 2022: a cross-sectional study.
Fuente:The Pan African Medical Journal
Extracto:
despite the good knowledge, favorable attitude and good
practices, the regular eye check-up practice was significantly low. Urban
residence was significantly associated with knowledge. Similarly, knowledge was
found to be significantly associated with practice level. The most common barrier
to regular eye check-up was the misconception that it is not important.
Claves:Diabetes mellitus, Dongola, Sudan, attitude, barrier, diabetic retinopathy, knowledge, practice
Cita:Pan Afr Med J 2024; 48 : 77.
Autor/es:Abumhadi, Mohammed (a) Amin, Othman (b)
institución:(a) Faculty of Medicine and Health Science, University of Dongola, Dongola, Northern State, Sudan. (b) Faculty of Medicine and Health Science, University of Dongola, Dongola, Northern State, Sudan.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Body composition analysis using bioelectric impedance in Bissau: reproducibility and level of agreement between two available devices.
Body composition analysis using bioelectric impedance in Bissau: reproducibility and level of agreement between two available devices.
Fuente:The Pan African Medical Journal
Extracto:
the results indicate a good level of
agreement between the two devices. In resource-limited settings, the Omron is
likely a reasonable substitute for more expensive body composition devices.
Claves:Bioelectrical impedance, Guinea-Bissau, Omron, Tanita, body composition
Cita:Pan Afr Med J 2024; 48 : 80.
Autor/es:Sanca, Lilica (a) Byberg, Stine (b)
institución:(a) Faculty of Sport Sciences and Physical Education, University of Coimbra, CIDAF-Research Center for Sport and Physical Activity, Coimbra, Portugal. (b) Center for Neuroscience and Cell Biology, Center for Innovative Biomedicine and Biotechnology, University of Coimbra, Coimbra, Portugal.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
In Vitro Alpha-Glucosidase Inhibitory Effect of Etlingera Elatior Ethanol Extract Growing in Gayo Highland, Aceh Province, Indonesia.
In Vitro Alpha-Glucosidase Inhibitory Effect of Etlingera Elatior Ethanol Extract Growing in Gayo Highland, Aceh Province, Indonesia.
Fuente:F1000research
Extracto:
This study highlights E.
elatior potency as a novel source of antioxidant and natural antidiabetic
compounds that are useful for the prevention and treatment of diabetes.
institución:(a) Department of Biology, Faculty of Mathematics and Natural Sciences, Universitas Syiah Kuala, Banda Aceh, Aceh, 23111, Indonesia. (b) Clinical Laboratory, Faculty of Veterinary Medicine, Universitas Syiah Kuala, Banda Aceh, Aceh, 23111, Indonesia.
Diabetes self-care and its associated factors among type 2 diabetes mellitus with chronic kidney disease patients in the East Coast of Peninsular Malaysia.
Diabetes self-care and its associated factors among type 2 diabetes mellitus with chronic kidney disease patients in the East Coast of Peninsular Malaysia.
Fuente:Peerj
Extracto:
The mean score for
diabetes self-care indicated a moderate level of self-care. The eGFR level and
diabetes distress were important factors influencing diabetes self-care
practices.
institución:(a) Department of Family Medicine, School of Medical Sciences, Health Campus, Universiti Sains Malaysia, Kubang Kerian, Kelantan, Malaysia. (b) Department of Family Medicine, School of Medical Sciences, Health Campus, Universiti Sains Malaysia, Kubang Kerian, Kelantan, Malaysia.
Conflicto:The authors declare there are no competing interests.
Causal effect of immune cells, metabolites, cathepsins, and vitamin therapy in diabetic retinopathy: a Mendelian randomization and cross-sectional study.
Causal effect of immune cells, metabolites, cathepsins, and vitamin therapy in diabetic retinopathy: a Mendelian randomization and cross-sectional study.
Fuente:Frontiers in Immunology
Extracto:
This study is the first to identify CAT H
as a key risk factor for DR, while vitamins B6 and E showed significant
protective effects, particularly against PDR. These findings suggest that CAT H,
along with vitamins B6 and E, could serve as therapeutic targets for DR. Further
validation through larger, multi-center studies is recommended to enhance the
accuracy and applicability of these findings.
institución:(a) Department of Endocrinology, The Affiliated Yancheng First Hospital of Nanjing University Medical School, The First People's Hospital of Yancheng, Yancheng, Jiangsu, China. (b) Department of Radiotherapy Oncology, The Affiliated Yancheng First Hospital of Nanjing University Medical School, The First People's Hospital of Yancheng, Yancheng, Jiangsu, China.
Conflicto:The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
Impaired Mycobacterium tuberculosis-specific T-cell memory phenotypes and functional profiles among adults with type 2 diabetes mellitus in Uganda.
Impaired Mycobacterium tuberculosis-specific T-cell memory phenotypes and functional profiles among adults with type 2 diabetes mellitus in Uganda.
Fuente:Frontiers in Immunology
Extracto:
Type 2 DM impairs the memory
phenotypes and functional profiles of Mtb-specific CD4(+) and CD8(+) T cells,
potentially indicating underlying immunopathology towards increased active TB
disease risk.
Autor/es:Ssekamatte, Phillip (a) Nabatanzi, Rose (b)
institución:(a) Department of Immunology and Molecular Biology, School of Biomedical Sciences, College of Health Sciences, Makerere University, Kampala, Uganda. (b) Medical Research Council/Uganda Virus Research Institute and London School of Hygiene & Tropical Medicine, Entebbe, Uganda.
Conflicto:The authors declare that the research was conducted without any commercial or financial relationships that could be construed as a potential conflict of interest.
