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The relationship between oxLDL, sLOX-1, PCSK9 and carotid intima-media thickness in patients with prediabetes and type 2 diabetes.
The relationship between oxLDL, sLOX-1, PCSK9 and carotid intima-media thickness in patients with prediabetes and type 2 diabetes.
Fuente:Scientific Reports
Extracto:
Our findings suggest that these biomarkers may be used as
potential markers for the assessment of cardiovascular risk in patients with
prediabetes and type 2 diabetes.
institución:(a) Department of Cardiology, Faculty of Medicine, Istanbul Atlas University, Istanbul, Turkey. drzeki@yahoo.com. (b) Department of Internal Medicine, Faculty of Medicine, Istanbul Atlas University, Istanbul, Turkey.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Autor/es:Madroñero, L Johana (a) Calvo, Eliana P (b)
institución:(a) Grupo de Virología, Vicerrectoría de Investigaciones, Universidad El Bosque, Bogotá, Colombia. (b) Grupo de Virología, Vicerrectoría de Investigaciones, Universidad El Bosque, Bogotá, Colombia. calvoeliana@unbosque.edu.co.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Clinical risk factors for sarcopenia in acute and chronic pancreatitis.
Clinical risk factors for sarcopenia in acute and chronic pancreatitis.
Fuente:Bmc Gastroenterology
Extracto:
Sarcopenia is
observed in both CP and AP. In addition to traditional risk factors (including
male sex, older age, and decreased subcutaneous fat), CP is independently
associated with sarcopenia. Further investigations are necessary to gain deeper
insights into sarcopenia pathogenesis, which could inform potential intervention
strategies.
institución:(a) Division of Gastroenterology, Hepatology, and Nutrition, The Ohio State University Wexner Medical Center, 410 West Tenth Avenue, Columbus, OH, 43210, USA. Mitchell.Ramsey@osumc.edu. (b) Department of Radiology, The Ohio State University Wexner Medical Center, Columbus, OH, USA.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Physical activity and motivational readiness for physical activity behavior change in adults with non-communicable diseases in Germany: a trend analysis of two cross-sectional health surveys from the German GEDA study 2014/2015 and 2019/2020.
Physical activity and motivational readiness for physical activity behavior change in adults with non-communicable diseases in Germany: a trend analysis of two cross-sectional health surveys from the German GEDA study 2014/2015 and 2019/2020.
Fuente:Bmc Public Health
Tipo de trabajo:Guía
Extracto:
Lower
rates of WHO PA recommendation fulfilment is recognized for most NCD groups
compared to the population without NCD for both surveys, but the proportion of
adults with NCD who meet the WHO PA recommendations differ widely between NCD
groups. A positive trend from 2014/15 to 2019/20 can only be seen for adults with
osteoarthritis. Based on our findings the implementation of PA promotion
particular with regards to motivational readiness and disease specific PA
measures is strongly recommended to improve prevention and ambulatory health care
for adults with NCD.
Claves:Exercise, Motivational readiness, Non-communicable disease, Physical activity, Transtheoretical model
Cita:BMC Public Health 2025 Feb 6; 25 (1) : 494.
Autor/es:Wenz, Benjamin (a) Graf, Jonathan (b)
institución:(a) Institute of Gerontology, Faculty I, Vechta University, Vechta, Germany. (b) University of Applied Sciences for Sport and Management Potsdam, Potsdam, Germany.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Tomographic features of lung damage associate with D-Dimer levels and further clinical outcome in patients with acute respiratory distress syndrome due to COVID-19.
Tomographic features of lung damage associate with D-Dimer levels and further clinical outcome in patients with acute respiratory distress syndrome due to COVID-19.
Fuente:Bmc Pulmonary Medicine
Extracto:
Tomographic extent of
lung involvement and the pattern of lung injury are related with coagulopathy
severity markers like D-Dimer, and own prognostic clinical ability in ARDS.
Autor/es:Suárez-Cuenca, Juan Antonio (a) Flores-Zaleta, José Fernando (b)
institución:(a) Unidad de Cuidados Intensivos, Corporativo Hospital Satélite. City of State of Mexico, Mexico, Mexico. suarej05@gmail.com. (b) Internal Medicine Department, Hospital General Xoco, SS CDMX, Mexico City, Mexico. suarej05@gmail.com.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
The association of triglyceride-glucose and triglyceride-glucose related indices with the risk of heart disease in a national.
The association of triglyceride-glucose and triglyceride-glucose related indices with the risk of heart disease in a national.
Fuente:Cardiovascular Diabetology
Tipo de trabajo:Estudio de cohortes
Extracto:
In the national population study, higher TyG-BMI,
TyG-WC, and TyG-WHtR indices were significantly associated with an increased risk
of heart disease, with TyG-BMI and TyG-WC showing stronger correlations. While
this association was evident in non-T2D patients, only TyG-BMI was associated
with heart disease incidence in T2D patients, underscoring the necessity for
further investigation.
Claves:Diabetes, Heart disease, Positive association, Triglyceride-glucose related indices, Triglyceride‑glucose index
Cita:Cardiovasc Diabetol 2025 Feb 6; 24 (1) : 54.
Autor/es:Tang, Xiaodi (a) Zhang, Kexin (b)
institución:(a) Department of Cardiovascular Medicine, Beijing Tsinghua Changgung Hospital, School of Clinical Medicine, Tsinghua University, No. 168 Litang Road, Changping District, Beijing, China. (b) Department of Cardiovascular Medicine, Beijing Tsinghua Changgung Hospital, School of Clinical Medicine, Tsinghua University, No. 168 Litang Road, Changping District, Beijing, China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Muscle quality index is correlated with insulin resistance and type 2 diabetes mellitus: a cross-sectional population-based study.
Muscle quality index is correlated with insulin resistance and type 2 diabetes mellitus: a cross-sectional population-based study.
Fuente:Bmc Public Health
Extracto:
This study
provides evidence that decreased levels of MQI are correlated with an increased
risk of IR and T2DM, indicating the potential utility as a marker for identifying
IR and T2DM.
institución:(a) Department of Rehabilitation Medicine, The First Affiliated Hospital of Zhejiang Chinese Medical University (Zhejiang Provincial Hospital of Chinese Medicine), Hangzhou City, China. (b) Department of Gastroenterology, Pingyang Hospital of Wenzhou Medical University, Wenzhou City, China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Associations of carbohydrate quality and cardiovascular risk factors vary among diabetes subtypes.
Associations of carbohydrate quality and cardiovascular risk factors vary among diabetes subtypes.
Fuente:Cardiovascular Diabetology
Extracto:
Associations of
carbohydrate quality parameters with blood lipids, subclinical inflammation, and
fatty liver index differed between diabetes subtypes. However, evidence is too
preliminary to derive subtype-specific recommendations. TRIAL REGISTRATION:
Clinicaltrials.gov: NCT01055093.
Autor/es:Weber, Katharina S (a) Schlesinger, Sabrina (b)
institución:(a) Institute of Epidemiology, Kiel University, Niemannsweg 11, 24105, Kiel, Germany. Katharina.Weber@epi.uni-kiel.de. (b) Institute for Biometrics and Epidemiology, German Diabetes Center, Leibniz Center for Diabetes Research at Heinrich Heine University Düsseldorf, Düsseldorf, Germany.
Conflicto:Declarations. Ethical approval and consent to participate: The study protocol has been approved by the ethics board of Heinrich Heine University. The study is conducted according to the ethical standards as laid down in the 1964 Declaration of Helsinki. All participants gave written informed consent. Consent for publication: Not applicable. Competing interest: A.E.B. is a member of the International Carbohydrate...
Quality Consortium (ICQC), a member of the Scientific committee of the transnational governance of the Nutri-Score system, a member of the Scientific Advisory Council for Agricultural Policy, Nutrition and Consumer Health Protection, Federal Ministry of Food and Agriculture Germany and a co-author of the popular cookbook “Nordisch abnehmen”. Her research is supported by grants from the German Research Foundation (BU 1807/3-2 & BU 1807/8-1), and the European Joint Programming Initiative “A Healthy Diet for a Healthy Life” and from the ERA-NET Cofund HDHL INTIMIC (GA No. 727565 of the EU Horizon 2020 Research and InnovationProgramme). M.R. received fees consulting, lecturing or serving on advisory boards from Astra Zeneca, Boehringer-Ingelheim, Echosens, Eli Lilly, Merck-MSD, Madrigal, Novo Nordisk, Madrigal and Target RWE and has performed investigator-initiated research with support from Boehringer-Ingelheim, Novo Nordisk and Nutricia/Danone to the DDZ. The research of M.R. is supported by grants from the German Research Foundation (DFG; RTG/GRK 2576), the European Community (HORIZON-HLTH-2022-STAYHLTH-02-01: Panel A) to the INTERCEPT-T2D consortium, BMG, MKW, BMBF and the Schmutzler-Stiftung. R.W. reports lecture fees from Novo Nordisk, Sanofi-Aventis, Boehringer-Ingelheim and Eli Lilly. He served on the advisory board for Akcea Therapeutics, Daiichi Sankyo, Eli Lilly and NovoNordisk. None of these aforementioned relationships/activities are related to the content of this manuscript. J.G., C.H., W.L., K.S.W., S.S., K.S., S.T., and O.P.Z. declare no competing interests.
The association between stress-induced hyperglycemia ratio and cardiovascular events as well as all-cause mortality in patients with chronic kidney disease and diabetic nephropathy.
The association between stress-induced hyperglycemia ratio and cardiovascular events as well as all-cause mortality in patients with chronic kidney disease and diabetic nephropathy.
Fuente:Cardiovascular Diabetology
Extracto:
SHR
may serve as a critical biomarker for prognostic assessment in these populations,
enabling clinicians to identify high-risk patients and tailor personalized
treatment strategies that enhance patient quality of life and mitigate mortality
risk.
institución:(a) Dongzhimen Hospital of Beijing University of Chinese Medicine, Beijing, China. (b) Second Clinical Medical College, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong, China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
The AFFIRM Framework for gender-affirming care: qualitative findings from the Transgender and Gender Diverse Health Equity Study.
The AFFIRM Framework for gender-affirming care: qualitative findings from the Transgender and Gender Diverse Health Equity Study.
Fuente:Bmc Public Health
Extracto:
Findings from this study
and the AFFIRM Framework which emerged from TGD patient narratives can be applied
to improve current care and set benchmarks for high-quality gender-affirming care
delivery and practice.
Claves:Health equity, Healthcare quality, LGBT health, Transgender
Cita:BMC Public Health 2025 Feb 6; 25 (1) : 491.
Autor/es:Quint, Meg (a) Bailar, Schuyler (b)
institución:(a) Stanford School of Medicine, Stanford, CA, 94305, USA. (b) Department of Epidemiology, University of Michigan, Ann Arbor, MI, 48109, USA.
Conflicto:Declarations. Ethics approval and consent to participate: This study was approved by the Mass General Brigham Institutional Review Board. All participants provided informed consent to participate. This research was conducted in accordance with the principles of the Belmont Report and the Declaration of Helsinki. Consent for publication: Not applicable. Competing interests: Reisner receives royalties from McGraw Hill for co-editing the textbook,...
, “Transgender and Gender Diverse Health Care: The Fenway Guide.”
Assessment of six insulin resistance surrogate indexes for predicting stroke incidence in Chinese middle-aged and elderly populations with abnormal glucose metabolism
Assessment of six insulin resistance surrogate indexes for predicting stroke incidence in Chinese middle-aged and elderly populations with abnormal glucose metabolism
Fuente:Cardiovascular Diabetology
Tipo de trabajo:Estudio de cohortes
Extracto:
The six IR surrogate indexes were closely associated with high risk
of stroke in individuals with abnormal glucose metabolism. The eGDR showed
promising potential in predicting stroke risk in Chinese middle-aged and elderly
populations with abnormal glucose metabolism.
institución:(a) Department of Laboratory, The First Affiliated Hospital of Wannan Medical College, Wuhu, Anhui, China. (b) Department of Laboratory, The First Affiliated Hospital of Wannan Medical College, Wuhu, Anhui, China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Global, regional, and national burden of type 2 diabetes mellitus caused by high BMI from 1990 to 2021, and forecasts to 2045: analysis from the global burden of disease study 2021.
Global, regional, and national burden of type 2 diabetes mellitus caused by high BMI from 1990 to 2021, and forecasts to 2045: analysis from the global burden of disease study 2021.
Fuente:Frontiers in Public Health
Extracto:
Our study reveals that the disease
burden of T2DM caused by high BMI is significantly increasing and is expected to
continue rising in the future. Women bear a heavier burden, particularly
postmenopausal women, and there are significant differences in the disease burden
across different geographical regions, and socioeconomic statuses. Targeted
considerations and specific strategies are essential to address these
disparities, thereby improving public health and reducing the burden.
Claves:deaths, disability-adjusted life years (DALYs), global burden of diseases (GBD), high body mass index (high BMI), socio-demographic index (SDI), type 2 diabetes mellitus (T2DM)
Cita:Front Public Health 2025; 13 : 1515797.
Autor/es:Huang, Xin (a) Wu, Yanyan (b)
institución:(a) Department of Endocrinology and Metabolism, The Fifth Affiliated Hospital of Wenzhou Medical University, Lishui Municipal Central Hospital, Lishui, China. (b) Department of Endocrinology and Metabolism, The Fifth Affiliated Hospital of Wenzhou Medical University, Lishui Municipal Central Hospital, Lishui, China.
Conflicto:The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
institución:(a) Department of Endocrinology Two, The First Affiliated Hospital of Anhui University of Chinese Medicine, Hefei, Anhui, China. (b) Center for Xin'an Medicine and Modernization of Traditional Chinese Medicine of IHM, The First Affiliated Hospital of Anhui University of Chinese Medicine, Hefei, Anhui, China.
Conflicto:The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
institución:(a) Department of Medical Oncology, Lu'an Hospital of Traditional Chinese Medicine Affiliated to Anhui University of Chinese Medicine, Lu'an, China. (b) Department of Orthopedics Department, Lu'an Hospital of Traditional Chinese Medicine Affiliated to Anhui University of Chinese Medicine, Lu'an, China.
Conflicto:The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
Associations between neutrophil percentage to albumin ratio and rheumatoid arthritis versus osteoarthritis: a comprehensive analysis utilizing the NHANES database.
Associations between neutrophil percentage to albumin ratio and rheumatoid arthritis versus osteoarthritis: a comprehensive analysis utilizing the NHANES database.
Fuente:Frontiers in Immunology
Extracto:
High levels of NPAR is positively
associated with the prevalence of RA. This provides us with new insights for the
management and treatment of RA patients.
Claves:National Health and Nutrition Examination Survey, cross-sectional study, inflammation, neutrophil percentage to albumin ratio, osteoarthritis, rheumatoid arthritis
Cita:Front Immunol 2025; 16 : 1436311.
Autor/es:Ding, Wenquan (a) La, Rui (b)
institución:(a) Department of Orthopedic Surgery, Orthopedic Institute, The First Affiliated Hospital of Soochow University, Soochow, Jiangsu, China. (b) Department of Orthopedic Surgery, Orthopedic Institute, The First Affiliated Hospital of Soochow University, Soochow, Jiangsu, China.
Conflicto:The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
Effects of practical models of low-volume high-intensity interval training on glycemic control and insulin resistance in adults
Effects of practical models of low-volume high-intensity interval training on glycemic control and insulin resistance in adults
Fuente:Frontiers in Endocrinology
Tipo de trabajo:Revisión sistemática
Extracto:
Conclusively, a
practical model of LV-HIIT with reduced intensity and extended interval was
effective in improving glucose control and its effects were similar to MICT.
Greater improvements were found in individuals with overweight/obesity or T2D in
protocols with longer intervals or accumulated interval duration per
session/week. More large-scale, randomized controlled studies with similar
intervention protocols in a wide range of population are warranted to confirm
these important results. SYSTEMATIC REVIEW REGISTRATION:
https://www.crd.york.ac.uk/prospero/, identifier CRD42024516594.
Claves:glucose, high-intensity interval training, insulin resistance, low-volume, practical model
institución:(a) Faculty of Sports Science, Ningbo University, Ningbo, China. (b) Centre for Population Health and Medical Informatics, Department of Sport, Physical Education and Health, Hong Kong Baptist University, Hong Kong, Hong Kong SAR, China.
Conflicto:The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. The author(s) declared that they were an editorial board member of Frontiers, at the time of submission. This had no impact on the peer review process and the final decision.
The role of activated partial thrombin time in mediating the impact of poorly glycemic control on diabetic peripheral neuropathy in patients with type 2 diabetes mellitus.
The role of activated partial thrombin time in mediating the impact of poorly glycemic control on diabetic peripheral neuropathy in patients with type 2 diabetes mellitus.
Fuente:Frontiers in Endocrinology
Extracto:
In patients with
T2DM, uncontrolled HbA1c and shorter APTT emerges as risk factors for DPN.
Additionally, the effect of increased HbA1c upon DPN, especially for influenced
conduction velocities of sensory fibers in both the ulnar nerve and sural nerve
may partly medicated by decreased APTT.
Claves:activated partial thrombin time, diabetic peripheral neuropathy, hyperglycemia, nerve conduction velocity, type 2 diabetes mellitus
institución:(a) Henan Key Laboratory of Rare Diseases, Endocrinology and Metabolism Center, The First Affiliated Hospital, and College of Clinical Medicine of Henan University of Science and Technology, Luoyang, China. (b) Department of Endocrinology, Institute of Endocrine and Metabolic Diseases, Centre for Leading Medicine and Advanced Technologies of IHM, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, China.
Conflicto:The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
Perioperative Factor Xa Inhibitor Discontinuation for Patients Undergoing Procedures With Minimal or Low Bleeding Risk.
Perioperative Factor Xa Inhibitor Discontinuation for Patients Undergoing Procedures With Minimal or Low Bleeding Risk.
Fuente:Jama Network Open
Tipo de trabajo:Estudio de cohortes
Extracto:
AND RELEVANCE: In
this cohort study, patients with AF receiving a factor Xa inhibitor and
undergoing a procedure with minimal to low bleeding risk had low rates of major
bleeding and thromboembolism when following the standardized PERIXa protocol for
perioperative management of oral anticoagulant treatment, suggesting that this
may be a safe and reasonable option for this patient population.
Cita:JAMA Netw Open 2025 Feb 3; 8 (2) : e2458742.
Autor/es:Lee, So-Ryoung (a) Lee, Kyung-Yeon (b)
institución:(a) Department of Internal Medicine, Seoul National University Hospital, Seoul, Republic of Korea. (b) Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Republic of Korea.
Conflicto:Conflict of Interest Disclosures: Dr Lip reported receiving consultant and speaker fees from Anthos, BMS/Pfizer, Boehringer Ingelheim, and Daiichi-Sankyo outside the submitted work. Dr Choi reported receiving grants from Abbott, Bayer, BMS/Pfizer, Biosense Webster, Chong Kun Dang, Daewoong Pharmaceutical, Daiichi-Sankyo, DeepQure, Dreamtech, Jeil Pharmaceutical, Medtronic, Samsung Electronics, Seers Technology, and Skylabs during the conduct of the study and receiving personal...
fees from Abbott, Bayer, BMS/Pfizer, Biosense Webster, Chong Kun Dang, Daewoong Pharmaceutical, Daiichi-Sankyo, DeepQure, Dreamtech, Jeil Pharmaceutical, Medtronic, Samsung Electronics, Seers Technology, and Skylabs outside the submitted work. No other disclosures were reported.
Industry Payments and Sentiments Toward Robotic Surgery Among US Physicians.
Industry Payments and Sentiments Toward Robotic Surgery Among US Physicians.
Fuente:Jama Network Open
Tipo de trabajo:Estudio de cohortes
Extracto:
AND RELEVANCE: In this cohort study of US-based
physicians, publicly available social media data were used to quantify
perceptions of robotic surgery. These findings demonstrate the potential of such
data to inform health care practices, guide balanced information dissemination,
and uphold the integrity of health information shared by physicians.
Cita:JAMA Netw Open 2025 Feb 3; 8 (2) : e2458552.
Autor/es:Loh, Wei San (a) Ibrahim, Andrew M (b)
institución:(a) Center for Healthcare Outcomes & Policy, University of Michigan, Ann Arbor. (b) Center for Healthcare Outcomes & Policy, University of Michigan, Ann Arbor.
Conflicto:Conflict of Interest Disclosures: Dr Sheetz reported receiving grants from the National Institute of Diabetes and Digestive and Kidney Diseases during the conduct of the study. No other disclosures were reported.
Effectiveness of Continuous Glucose Monitoring on Short-Term, In-Hospital Mortality Among Frail and Critically Ill Patients With COVID-19: Randomized Controlled Trial.
Effectiveness of Continuous Glucose Monitoring on Short-Term, In-Hospital Mortality Among Frail and Critically Ill Patients With COVID-19: Randomized Controlled Trial.
Fuente:Journal of Medical Internet Research
Tipo de trabajo:Estudio aleatorizado y controlado
Extracto:
We found a
significant clinical benefit from the use of CGM among frail and critically ill
patients with COVID-19. These findings support the use of CGM in the ICU and
might help with the extension of application in various in-hospital settings.
TRIAL REGISTRATION: Chinese Clinical Trial Registry ChiCTR2200059733;
https://www.chictr.org.cn/showproj.html?proj=169257.
Claves:CGM, COVID-19, ICU, POCT, SARS-CoV-2, clinical trial, continuous glucose monitoring, critically ill, exploratory, frail, glucose monitoring, in-ICU mortality, in-hospital mortality, inpatient mortality, intensive care unit, intermittently scanned continuous glucose monitoring, isCGM, mortality, open label, parallel, point of care testing, prospective, randomized, single center
Cita:J Med Internet Res 2025 Feb 7; 27 : e67012.
Autor/es:Shang, Jiawei (a) Yuan, Ziming (b)
institución:(a) Department of Intensive Care Medicine, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China. (b) Department of Intensive Care Medicine, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.
