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The increasing number of Open Access articles widens the reading offer
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Adiponectin C1Q and Collagen Domain Containing rs266729, Cyclin-Dependent Kinase Inhibitor 2A and 2B rs10811661, and Signal Sequence Receptor Subunit 1 rs9505118 Polymorphisms and Their Association with Gestational Diabetes Mellitus: A Case-Control Study in a Romanian Population.
Adiponectin C1Q and Collagen Domain Containing rs266729, Cyclin-Dependent Kinase Inhibitor 2A and 2B rs10811661, and Signal Sequence Receptor Subunit 1 rs9505118 Polymorphisms and Their Association with Gestational Diabetes Mellitus: A Case-Control Study in a Romanian Population.
Fuente:International Journal of Molecular Sciences
Extracto:
Our results suggest that the ADIPOQ rs266729, the CDKN2A/2B rs10811661, and the
SSR1 rs9505118 gene polymorphisms are not associated with GDM in a cohort of
Romanian pregnant women.
Autor/es:Muntean, Mihai (a) Mărginean, Claudiu (b)
institución:(a) Department of Obstetrics and Gynecology 2, George Emil Palade University of Medicine, Pharmacy, Science, and Technology of Târgu Mureș, 540142 Târgu Mureș, Romania. (b) Department of Obstetrics and Gynecology 2, George Emil Palade University of Medicine, Pharmacy, Science, and Technology of Târgu Mureș, 540142 Târgu Mureș, Romania.
Association of Oxidative Stress Markers with Incident Hyperglycemia in Gestational Diabetes Mellitus in an Educational Intervention.
Association of Oxidative Stress Markers with Incident Hyperglycemia in Gestational Diabetes Mellitus in an Educational Intervention.
Fuente:Nutrients
Extracto:
Higher
concentrations of plasma markers of oxidative stress are associated with
postpartum incident hyperglycemia in women with gestational diabetes.
Autor/es:Ruiz-Martínez, Mónica L (a) Gómez-Díaz, Rita A (b)
institución:(a) Unidad de Investigación Médica en Epidemiología Clínica UMAE HE CMN SXXI, Instituto Mexicano del Seguro Social (IMSS), Av. Cuauhtemoc 330, Mexico City 06720, Mexico. (b) Unidad de Investigación Médica en Epidemiología Clínica UMAE HE CMN SXXI, Instituto Mexicano del Seguro Social (IMSS), Av. Cuauhtemoc 330, Mexico City 06720, Mexico.
Rapid and high-sensitivity screening of pregnancy complications by profiling circulating placental extracellular vesicles.
Rapid and high-sensitivity screening of pregnancy complications by profiling circulating placental extracellular vesicles.
Fuente:Science Advances
Extracto:
This nanoplatform identifies individuals at
risk of developing pregnancy complications with a >90% classification accuracy,
exhibiting potential for clinical applications.
Cita:Sci Adv 2025 Feb 28; 11 (9) : eadr4074.
Autor/es:Palma, Carlos (a) Masud, Mostafa Kamal (b)
institución:(a) Translational Extracellular Vesicles in Obstetrics and Gynae-Oncology Group, University of Queensland Centre for Clinical Research, Faculty of Medicine, Royal Brisbane and Women's Hospital, The University of Queensland, Herston, QLD 4006, Australia. (b) UQ Centre for Extracellular Vesicle Nanomedicine, Faculty of Medicine, The University of Queensland, Herston, QLD 4006, Australia.
Forecasting total and cause-specific health expenditures for 116 health conditions in Norway, 2022-2050.
Forecasting total and cause-specific health expenditures for 116 health conditions in Norway, 2022-2050.
Fuente:Bmc Medicine
Extracto:
Health spending growth
was forecasted regardless of the scenario, and Norway needs to plan for this.
However, policymakers can curb total spending growth, while maintaining health
care quality and output, by ensuring more efficient allocation and effective use
of resources. While the overall impact of behavioral and metabolic risk
reductions on total healthcare spending was modest, reducing risk factors is
needed if countries aim to achieve a healthier, longer-living population.
Claves:Aging, Behavioral risk factors, Forecasting, Health expenditures, Health policy
Cita:BMC Med 2025 Feb 25; 23 (1) : 116.
Autor/es:Kinge, Jonas Minet (a) Øien, Henning (b)
institución:(a) Department of Health Management and Health Economics, Faculty of Medicine, University of Oslo, Oslo, Norway. Jonas.minet.kinge@fhi.no. (b) Norwegian Institute of Public Health, Postboks 222 Skøyen, Oslo, 0213, Norway. Jonas.minet.kinge@fhi.no.
Conflicto:Declarations. Ethics approval and consent to participate: The microdata used for the Norwegian Health Spending Project was approved, and participant consent was waived, by the Regional Committee for Medical and Health Research Ethics South-East Norway, reference number 184544. Consent for publication: Not applicable. Competing interests: GS has received honoraria for giving lectures at symposia sponsored by Eisai and Eli-Lilly. GS had...
d participated at advisory boards for Eisai and Eli-Lilly concerning anti-amyloid treatment in Alzheimer’s disease.
Autor/es:Almarzooq, Mohammed A (a) Almarzoug, Hussain A (b)
institución:(a) College of Medicine, King Faisal University, Al-Ahsa 31982, Saudi Arabia. (b) College of Medicine, King Faisal University, Al-Ahsa 31982, Saudi Arabia.
Assessment of Quality of Life in Lithuanian Patients with Multimorbidity Using the EQ-5D-5L Questionnaire.
Assessment of Quality of Life in Lithuanian Patients with Multimorbidity Using the EQ-5D-5L Questionnaire.
Fuente:Medicina (kaunas, Lithuania)
Extracto:
Conclusions: It is
found that the Lithuanian EQ-5D-5L questionnaire is suitable for the assessment
of the quality of life in patients with multimorbidity and indicates lower
quality of life among those with specific cardiovascular and joint disorder
chronic conditions and, in particular, demographic groups.
Claves:EQ-5D-5L, SF-36, chronic disease, multimorbidity, primary healthcare, quality of life
Cita:Medicina (Kaunas) 2025 Feb 8; 61 (2)
Autor/es:Vasiliauskienė, Olga (a) Vasiliauskas, Dovydas (b)
institución:(a) Department of Family Medicine, Lithuanian University of Health Sciences, LT-44307 Kaunas, Lithuania. (b) Department of Chemistry, The University of Chicago, Chicago, IL 60637, USA.
institución:(a) Department of Medicine IV, LMU University Hospital, LMU Munich, 80336 Munich, Germany. (b) Department of Medicine IV, LMU University Hospital, LMU Munich, 80336 Munich, Germany.
Comparative Study of Oxidative Stress Responses in Pediatric Type 1 Diabetes and Transient Hyperglycemia.
Comparative Study of Oxidative Stress Responses in Pediatric Type 1 Diabetes and Transient Hyperglycemia.
Fuente:International Journal of Molecular Sciences
Extracto:
The oxidative
state remained unchanged in the healthy participants experiencing temporary
hyperglycemia, even though T1DM altered the link between selenium, zinc, and
lipids.
Autor/es:Pinzaru, Anca Daniela (a) Lupu, Ancuta (b)
institución:(a) Pediatrics, County Clinical Emergency Hospital of Constanta, 900591 Constanta, Romania. (b) Department of Pediatrics, Faculty of Medicine, "Ovidius" University, 900470 Constanta, Romania.
The Proteome of Exosomes at Birth Predicts Insulin Resistance, Adrenarche and Liver Fat in Childhood.
The Proteome of Exosomes at Birth Predicts Insulin Resistance, Adrenarche and Liver Fat in Childhood.
Fuente:International Journal of Molecular Sciences
Extracto:
These data
suggest that DEPs at birth may predict insulin resistance, adrenarche and/or
ectopic adiposity in SGA children at age 7, when an early insulin-sensitizing
intervention could be considered.
institución:(a) Endocrinology Department, Institut de Recerca Sant Joan de Déu, University of Barcelona, 08950 Barcelona, Spain. (b) Centro de Investigación Biomédica en Red de Diabetes y Enfermedades Metabólicas Asociadas (CIBERDEM), Instituto de Salud Carlos III, 28029 Madrid, Spain.
The Impact of Long-Term Parenteral Nutrition on Physical Development and Bone Mineralization in Children with Chronic Intestinal Failure.
The Impact of Long-Term Parenteral Nutrition on Physical Development and Bone Mineralization in Children with Chronic Intestinal Failure.
Fuente:Nutrients
Extracto:
The physical development of children who require long-term
parenteral nutrition due to intestinal failure is poorer than that of healthy
children. Although there are risk factors for bone mineralization disorders in
children with intestinal failure, no clinical issues, such as pathological
fractures, have been observed.
Claves:children, growth, intestinal failure, metabolic bone disease, parenteral nutrition
Cita:Nutrients 2025 Feb 7; 17 (4)
Autor/es:Romanowska, Hanna (a) Danko, Mikołaj (b)
institución:(a) Department of Pediatrics, Endocrinology, Diabetology, Metabolic Diseases and Cardiology of the Developmental Age, Pomeranian Medical University, 71-252 Szczecin, Poland. (b) Department of Pediatrics, Nutrition and Metabolic Diseases, The Children's Memorial Health Institute, 04-730 Warsaw, Poland.
Nutritional Status in Children with Celiac Disease and Type 1 Diabetes Mellitus-A Narrative Review.
Nutritional Status in Children with Celiac Disease and Type 1 Diabetes Mellitus-A Narrative Review.
Fuente:Nutrients
Extracto:
Children with T1DM and longer
time with positive serology for CD have lower levels of ferritin, vitamin D 25OH,
and folate and also lower bone mineral density.
Autor/es:Pop, Daniela (a) Ichim, Edita Gabriela (b)
institución:(a) Third Pediatric Discipline, "Iuliu Hațieganu" University of Medicine and Pharmacy, 400217 Cluj-Napoca, Romania. (b) Third Pediatric Department, Emergency Hospital for Children, 400217 Cluj-Napoca, Romania.
Developing and Evaluating an Interactive, Case-Based, Web-Based Active Learning Tool for Primary Care Physicians (Community Fracture Capture Learning Hub): Protocol for an Acceptability and Engagement Study.
Developing and Evaluating an Interactive, Case-Based, Web-Based Active Learning Tool for Primary Care Physicians (Community Fracture Capture Learning Hub): Protocol for an Acceptability and Engagement Study.
Fuente:Jmir Research Protocols
Extracto:
The study described in this protocol will provide important insights
into the function and effectiveness of the CFC Learning Hub. This information
will guide the expansion of the program. This initiative offers a simple digital
solution for promoting current bone health practices tailored to PCPs' needs and
thereafter to expand the rollout of the e-learning hub and implementation of
fracture liaison models at a primary care level in Australia and elsewhere.
Future applications may extend to other clinical areas and professions.
INTERNATIONAL REGISTERED REPORT IDENTIFIER (IRRID): DERR1-10.2196/57511.
Claves:case-based education, community-based fracture capture bone hub, continuing professional development, osteoporosis, primary care physicians, virtual communities of practice, web-based learning platform
Cita:JMIR Res Protoc 2025 Feb 25; 14 : e57511.
Autor/es:Fathalla, Ahmed M (a) Chiang, Cherie (b)
institución:(a) Department of Medicine, The Royal Melbourne Hospital, University of Melbourne, Melbourne, Australia. (b) Department of Medicine, The Royal Melbourne Hospital, University of Melbourne, Melbourne, Australia.
Perceptions of Endocrine Clinicians Regarding Climate Change and Health.
Perceptions of Endocrine Clinicians Regarding Climate Change and Health.
Fuente:International Journal of Environmental Research and Public Health
Extracto:
We also exposed an untapped interest in developing
endocrine-specific climate and health curricula.
Claves:climate change, endocrine clinicians, health impacts, survey
Cita:Int J Environ Res Public Health 2025 Jan 21; 22 (2)
Autor/es:Steinmetz-Wood, Samantha (a) Kennedy, Amanda G (b)
institución:(a) Division of Endocrinology, Diabetes & Osteoporosis, The University of Vermont Larner College of Medicine, Burlington, VT 05401, USA. (b) Department of Medicine Quality Program, The University of Vermont Larner College of Medicine, Burlington, VT 05401, USA.
A cross-sectional study exploring relationships between triglyceride glucose index, atherogenic index of plasma, and chronic pain: NHANES 1999-2004.
A cross-sectional study exploring relationships between triglyceride glucose index, atherogenic index of plasma, and chronic pain: NHANES 1999-2004.
Fuente:Lipids in Health and Disease
Extracto:
Nonlinear correlations between the TyG index, AIP, and chronic pain
were identified among adults in the United States. This demonstrated that the TyG
index and AIP displayed similar effectiveness in predicting the risk of chronic
pain.
institución:(a) Mudanjiang Collaborative Innovation Center for Development and Application of Northern Medicinal Resources, Mudanjiang, 157000, China. (b) Mudanjiang Medical University, Mudanjiang, 157000, China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
A Genetic Test to Identify People at High Risk of Heart Failure.
A Genetic Test to Identify People at High Risk of Heart Failure.
Fuente:International Journal of Molecular Sciences
Extracto:
These
results highlight the critical role of genetic factors in the development of
heart failure and demonstrate this test's potential as a significant tool for
clinical HF risk prediction.
institución:(a) Centre for Diabetes Research, Harry Perkins Institute of Medical Research, Nedlands, WA 6009, Australia. (b) Stroke Research Centre, Perron Institute for Neurological and Translational Science, Nedlands, WA 6009, Australia.
Changes in Sexual Functioning in Women with Severe Obesity After Bariatric Surgery: Impact of Postoperative Adherence to Mediterranean Diet.
Changes in Sexual Functioning in Women with Severe Obesity After Bariatric Surgery: Impact of Postoperative Adherence to Mediterranean Diet.
Fuente:Nutrients
Extracto:
Bariatric surgery significantly improves female sexual
function, with the Mediterranean diet enhancing these benefits during the
postoperative period. Future studies must investigate additional variables such
as psychological factors, physical activity, and other lifestyle changes that may
also influence sexual function.
Claves:Mediterranean diet, adherence, bariatric surgery, female sexual function index, lubrication, metabolic syndrome, orgasm, satisfaction, severe obesity, type 2 diabetes mellitus
institución:(a) San Juan de Dios Foundation, 28036 Madrid, Spain. (b) Health Sciences Department, San Juan de Dios School of Nursing and Physical Therapy, Comillas Pontifical University, 28036 Madrid, Spain.
High Rates of Abnormal Glucose Metabolism Detected by 75 g Oral Glucose Tolerance Test in Major Psychiatric Patients with Normal HbA1c and Fasting Glucose Levels.
High Rates of Abnormal Glucose Metabolism Detected by 75 g Oral Glucose Tolerance Test in Major Psychiatric Patients with Normal HbA1c and Fasting Glucose Levels.
Fuente:Nutrients
Extracto:
Conclusions: The results suggest that relatively
high proportions of patients with a major psychiatric disorder remain undetected
by routine indices for abnormal glucose metabolism, indicating the importance of
OGTT even if the patients showed non-diabetic levels in blood glucose or HbA1c.
Claves:75 g oral glucose tolerance test, bipolar disorder, diabetes, glucose metabolism, major depressive disorder, schizophrenia
Cita:Nutrients 2025 Feb 8; 17 (4)
Autor/es:Yoshida, Sumiko (a) Aizawa, Emiko (b)
institución:(a) Department of Psychiatric Rehabilitation, National Center of Neurology and Psychiatry Hospital, Tokyo 187-8551, Japan. (b) Mood Disorder Center for Advanced Therapy, National Center of Neurology and Psychiatry Hospital, Tokyo 187-8551, Japan.
Nonlinear association between glycated hemoglobin levels and mortality in elderly patients with non-diabetic chronic kidney disease: a national health and nutrition examination survey analysis.
Nonlinear association between glycated hemoglobin levels and mortality in elderly patients with non-diabetic chronic kidney disease: a national health and nutrition examination survey analysis.
Fuente:Frontiers in Endocrinology
Tipo de trabajo:Estudio de cohortes
Extracto:
This cohort study suggests that both low and high HbA1c levels are
associated with an increased risk of all-cause mortality in elderly patients with
non-diabetic CKD.
institución:(a) Department of Clinical Laboratory, The Second Affiliated Hospital of Gannan Medical University, Ganzhou, China. (b) Department of Clinical Laboratory, The Second Affiliated Hospital of Gannan Medical University, Ganzhou, China.
Conflicto:The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
Epimaps of the SARS-CoV-2 Receptor-Binding Domain Mutational Landscape: Insights into Protein Stability, Epitope Prediction, and Antibody Binding.
Epimaps of the SARS-CoV-2 Receptor-Binding Domain Mutational Landscape: Insights into Protein Stability, Epitope Prediction, and Antibody Binding.
Fuente:Biomolecules
Extracto:
Future antibody development could focus on broadly neutralising antibodies,
engineering antibodies with enhanced binding affinity, and targeting spike
protein regions beyond the RBD.
