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The blood urea nitrogen-to-creatinine ratio is associated with acute kidney injury among COVID-19 patients.
The blood urea nitrogen-to-creatinine ratio is associated with acute kidney injury among COVID-19 patients.
Fuente:Renal Failure
Tipo de trabajo:Guía
Extracto:
The BCR, a simple index, is associated with AKI
onset and mortality in COVID-19 patients. The BCR possesses certain specificity
for AKI screening, which indicates an effective clinical indicator for screening
patients at high risk of AKI.
institución:(a) Department of Nephrology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. (b) Department of Nephrology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Conflicto:No potential conflict of interest was reported by the author(s).
Relationships Between Brain Glucose Metabolism Patterns and Impaired Glycemic Status
Relationships Between Brain Glucose Metabolism Patterns and Impaired Glycemic Status
Fuente:Human Brain Mapping
Tipo de trabajo:Revisión sistemática
Extracto:
This can suggest that even in cognitively normal
individuals, insulin resistance can potentially increase the predisposition to
abnormal AD-like glucose metabolism.
institución:(a) Clinical Research Development Center, Taleghani and Imam Ali Hospital, Kermanshah University of Medical Sciences, Kermanshah, Iran. (b) Mallinckrodt Institute of Radiology, Washington University in St. Louis, St. Louis, Missouri, USA.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Impact of Muscle Quality on Muscle Strength and Physical Performance Beyond Muscle Mass or Diabetes Status.
Impact of Muscle Quality on Muscle Strength and Physical Performance Beyond Muscle Mass or Diabetes Status.
Fuente:Journal of Cachexia, Sarcopenia and Muscle
Extracto:
Reduced myosteatosis was positively associated with greater muscle
strength and better physical performance in both men and women, regardless of
muscle mass or diabetes status; improving myosteatosis may be a therapeutic
target for the prevention of sarcopenia.
institución:(a) Division of Endocrinology and Metabolism, Department of Internal Medicine, Korea University Anam Hospital, Seoul, Republic of Korea. (b) Institute of Human Genomic Study, College of Medicine, Korea University, Seoul, Republic of Korea.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Autor/es:Dantas, Wagner S (a) Heintz, Elizabeth C (b)
institución:(a) Integrated Physiology and Molecular Medicine Laboratory, Pennington Biomedical Research Center, Louisiana State University, Baton Rouge, Louisiana, USA. (b) Lerner Research Institute, Cleveland Clinic Foundation, Cleveland, Ohio, USA.
Conflicto:c.e.F. is currently an investigator at Mission Therapeutics, a company with commercial interest in deubiquinating enzymes (DUB) drug discovery and development. Mission Therapeutics had no role in the design and conduct of the study, collection, analysis or interpretation of the data, manuscript preparation or review.
Perceived Discrimination in Health Care Settings and Care Delays in Patients With Diabetes and Hypertension.
Perceived Discrimination in Health Care Settings and Care Delays in Patients With Diabetes and Hypertension.
Fuente:Jama Network Open
Extracto:
AND RELEVANCE: These findings suggest that higher PDHS is positively
associated with delaying health care due to nervousness about seeing a health
care professional. The largest mediation proportion observed was among younger
adults and racial and ethnic minority groups. By prioritizing better PCC, health
care delays associated with patient apprehension related to perceived
discrimination may be reduced.
Cita:JAMA Netw Open 2025 Mar 3; 8 (3) : e250046.
Autor/es:Jafari Bidgoli, Maryam (a) Wang, Hui (b)
institución:(a) Department of Community Medicine and Population Health, College of Community Health Sciences, The University of Alabama, Tuscaloosa. (b) Institute for Rural Health Research, The University of Alabama, Tuscaloosa.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Advance in peptide-based drug development: delivery platforms, therapeutics and vaccines.
Advance in peptide-based drug development: delivery platforms, therapeutics and vaccines.
Fuente:Signal Transduction and Targeted Therapy
Extracto:
The accelerated advancement in the
development of novel peptide-based therapeutics, including peptide-drug
complexes, new peptide-based vaccines, and innovative peptide-based diagnostic
reagents, has the potential to promote the era of precise customization of
disease therapeutic schedule.
institución:(a) Department of Pharmacy, The General Hospital of Western Theater Command, Chengdu, 610083, China. (b) Department of Pharmacy, Personalized Drug Therapy Key Laboratory of Sichuan Province, Sichuan Academy of Medical Sciences & Sichuan Provincial People's Hospital, School of Medicine, University of Electronic Science and Technology of China, Chengdu, 610072, China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
In-depth profile of biosignatures for T2DM cohort utilizing an integrated targeted LC-MS platform.
In-depth profile of biosignatures for T2DM cohort utilizing an integrated targeted LC-MS platform.
Fuente:Scientific Data
Extracto:
We hereby make these
technical validation results and the profiling dataset publicly available to the
scientific community, showcasing its exceptional sensitivity and robustness as an
invaluable tool for the comprehensive targeted metabolome analysis.
Cita:Sci Data 2025 Mar 4; 12 (1) : 377.
Autor/es:Ma, Shurong (a) Yang, Lu (b)
institución:(a) Laboratory of Integrative Medicine, The First Affiliated Hospital of Dalian Medical University, Dalian, Liaoning, 116000, P. R. China. (b) Institute (College) of Integrative Medicine, Dalian Medical University, Dalian, Liaoning, 116000, P. R. China.
Conflicto:Competing interests: Z.M.W. and P.Y.Y. are cofounders of IPhenome Biotechnology (Yunpukang) Inc, Dalian. Other authors declare no competing interests.
Evaluation of sociodemographic and nutrition-related factors for type 2 diabetes risk: a sample from Turkiye.
Evaluation of sociodemographic and nutrition-related factors for type 2 diabetes risk: a sample from Turkiye.
Fuente:Bmc Public Health
Extracto:
Our findings suggest that increasing age, increasing BMI, lower
education level, and having a disease diagnosis can be significant risk factors
for diabetes. However, more studies are needed to clarify risk factors,
especially those related to nutrition.
Claves:Nutrition, Obesity, Sociodemographic factors, Type 2 diabetes mellitus: FINDRISC
Cita:BMC Public Health 2025 Mar 4; 25 (1) : 858.
Autor/es:Karaca-Çelik, K Esen (a) Toprak, Dilek (b)
institución:(a) Izmir Demokrasi University, Faculty of Health Sciences, Department of Nutrition and Dietetics, Istanbul, Türkiye. (b) Istanbul Atlas University, Department of Family Medicine, Faculty of Medicine, Istanbul, Türkiye.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Emerging role of IGF1R and IR expression and localisation in adrenocortical carcinomas.
Emerging role of IGF1R and IR expression and localisation in adrenocortical carcinomas.
Fuente:Cell Communication and Signaling Ccs
Extracto:
Overall, these data suggest that IGF1R localisation and
IR expression represent new biomarkers predicting tumour aggressiveness, as well
as possible molecular markers useful to patients' stratification for more
individualized IGF1R-IR targeted therapies or for novel pharmacological
approaches specifically targeting IRA isoform.
institución:(a) Department of Clinical Sciences and Community Health, University of Milan, 20122, Milan, Italy. (b) Department of Clinical Sciences and Community Health, University of Milan, 20122, Milan, Italy.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Autor/es:Boelig, Rupsa C (a) Foecke Munden, Emily (b)
institución:(a) Division of Maternal Fetal Medicine, Department of Obstetrics and Gynecology, Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, Pennsylvania, USA. (b) Department of Pharmacology, Physiology, and Cancer Biology, Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, Pennsylvania, USA.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Sex Differences in the Efficacy of Glucagon-Like Peptide-1 Receptor Agonists for Weight Reduction
Sex Differences in the Efficacy of Glucagon-Like Peptide-1 Receptor Agonists for Weight Reduction
Fuente:Journal of Diabetes
Tipo de trabajo:Revisión sistemática
Extracto:
Females lost more
weight than males when treated with GLP-1RAs for weight reduction. The sex
difference in weight reduction became more pronounced as the degree of weight
reduction increased. Indications for obesity could magnify this sex difference.
Cita:J Diabetes 2025 Mar; 17 (3) : e70063.
Autor/es:Yang, Yucheng (a) He, Liyun (b)
institución:(a) Department of Endocrinology, Key Laboratory of Endocrinology of National Health Commission, Translation Medicine Center, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China. (b) Diabetes Research Center of Chinese Academy of Medical Sciences, Beijing, China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Efficacy and Safety of Colquhounia Root Tablet for Chronic Glomerulopathy: A Real-World Survey With Bioinformatics Insights.
Efficacy and Safety of Colquhounia Root Tablet for Chronic Glomerulopathy: A Real-World Survey With Bioinformatics Insights.
Fuente:Drug Design, Development and Therapy
Extracto:
CRT
treatment for chronic glomerulopathy is safe and effective, which can
significantly reduce proteinuria. Network pharmacology results suggest the
mechanism of CRT in chronic glomerulopathy may involve Th17 cell differentiation
and CLR signaling pathway.
institución:(a) Department of Nephrology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, People's Republic of China. (b) Department of Gynecologic Oncology, Hubei Cancer Hospital, Wuhan, Hubei, 430070, People's Republic of China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Glycemic fluctuations, fatigue, and sleep disturbances in type 2 diabetes during ramadan fasting: A cross-sectional study.
Glycemic fluctuations, fatigue, and sleep disturbances in type 2 diabetes during ramadan fasting: A cross-sectional study.
Fuente:Plos One
Extracto:
Hypoglycemia and
hyperglycemia are common among people with type 2 diabetes during Ramadan.
Fatigue and poor sleep quality were also widespread. Key factors linked to these
glycemic fluctuations were pre-Ramadan HbA1c levels and fatigue, while sleep
quality was particularly associated with hyperglycemia. These results highlight
the need for personalized care to manage blood sugar levels and improve overall
health during Ramadan. We recommend that healthcare providers advise patients
with type 2 diabetes to aim for 7-8 hours of sleep per night to help control
blood glucose levels. Additionally, having three meals a day (Suhoor, Iftar, and
a post-Iftar snack) with low glycemic index foods can help maintain stable blood
glucose and prevent both hypoglycemia and hyperglycemia during Ramadan.
institución:(a) Department of Nutrition, Faculty of Sport and Health Sciences, Universitas Negeri Surabaya, Surabaya, Indonesia. (b) Diabetes Connection Care, Eka Hospital Bumi Serpong Damai, Tangerang, Indonesia.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Causes, management and outcomes of polyhydramnios at a secondary level hospital in Cape Town, South Africa.
Causes, management and outcomes of polyhydramnios at a secondary level hospital in Cape Town, South Africa.
Fuente:Plos One
Tipo de trabajo:Estudio de cohortes
Extracto:
Adverse outcomes were related to
severity of the polyhydramnios and were significantly lower in the mild compared
to the moderate and severe groups, with the rate of adverse outcome in the mild
group comparable to that of the general population. Early delivery before 40
weeks gestation may be associated with benefit in moderate and severe groups of
polyhydramnios.
Cita:PLoS One 2025; 20 (3) : e0317256.
Autor/es:Siveregi, Amon (a) Horak, Anne (b)
institución:(a) Mowbray Maternity Hospital, Cape Town, Western Cape, South Africa. (b) Department of Obstetrics and Gynaecology, University of Cape Town, Groot Schuur Hospital, Cape Town, South Africa.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Prevalence and associated factors of chronic kidney disease among diabetes mellitus patients in Ethiopia
Prevalence and associated factors of chronic kidney disease among diabetes mellitus patients in Ethiopia
Fuente:Plos One
Tipo de trabajo:Revisión sistemática
Extracto:
The prevalence of CKD in Ethiopia was high,
affecting nearly two in five individuals with diabetes. In addition, factors such
as older age, rural residence, longer DM duration, positive proteinuria, lower
HDL-C levels, and a family history of CKD were significantly associated with CKD
prevalence. Therefore, targeted public health interventions, such as screening,
education, and awareness programs, are highly recommended to mitigate this
problem. SYSTEMATIC REVIEW REGISTRATIONS: PROSPERO (2024: CRD42024576958).
institución:(a) Department of Epidemiology and Biostatistics, Institute of Public Health, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia. (b) Department of Epidemiology and Biostatistics, Institute of Public Health, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Dietary energy intake predicts mortality in Chinese patients with peritoneal dialysis: a single-center 18 years' follow-up study.
Dietary energy intake predicts mortality in Chinese patients with peritoneal dialysis: a single-center 18 years' follow-up study.
Fuente:Bmc Nephrology
Tipo de trabajo:Estudio de cohortes
Extracto:
Our study revealed that DEI 30-34.99 kcal/kg/day might be beneficial
to the long-term outcome for the Chinese PD population. CLINICAL TRIAL NUMBER:
Not applicable.
Claves:Cohort study, Dietary energy intake, Mortality, Peritoneal dialysis
Cita:BMC Nephrol 2025 Mar 5; 26 (1) : 120.
Autor/es:Liu, Su-Xuan (a) Xu, Ke (b)
institución:(a) Department of Nephrology, Peking University Third Hospital, Beijing, China. (b) Department of Nephrology, Peking University Third Hospital, Beijing, China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Association between protein intake and sources in mid-pregnancy and the risk of gestational diabetes mellitus.
Association between protein intake and sources in mid-pregnancy and the risk of gestational diabetes mellitus.
Fuente:Bmc Pregnancy and Childbirth
Tipo de trabajo:Orientaciones y guía
Extracto:
The intake of total protein and animal protein, especially eggs, dairy products,
and fish, can reduce the risk of GDM while consuming unprocessed red meat
increases the risk. There is no significant association between the intakes of
plant protein, processed meat, and poultry meat and the occurrence of GDM. The
results of this study are expected to provide a basis for precise nutritional
education, health guidance during pregnancy, and early prevention of GDM.
Cita:BMC Pregnancy Childbirth 2025 Mar 6; 25 (1) : 240.
Autor/es:Wang, Rui (a) Jin, Xingyi (b)
institución:(a) Key Laboratory of Environmental Medicine and Engineering of Ministry of Education, Department of Nutrition and Food Hygiene, School of Public Health, Southeast University, Nanjing, 210009, China. (b) Key Laboratory of Environmental Medicine and Engineering of Ministry of Education, Department of Nutrition and Food Hygiene, School of Public Health, Southeast University, Nanjing, 210009, China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Atherogenic index of plasma, high sensitivity C-reactive protein and incident diabetes among middle-aged and elderly adults in China
Atherogenic index of plasma, high sensitivity C-reactive protein and incident diabetes among middle-aged and elderly adults in China
Fuente:Cardiovascular Diabetology
Tipo de trabajo:Estudio de cohortes
Extracto:
This cohort suggests combined effects and mutual
mediation between the AIP and hsCRP on incident diabetes in China. Our findings
provide clinical implications for monitoring and managing AIP and hsCRP levels to
mitigate the development of diabetes.
Claves:Atherogenic index of plasma, C-reactive protein, Diabetes, Inflammation, Middle-aged and older adults
Cita:Cardiovasc Diabetol 2025 Mar 5; 24 (1) : 103.
Autor/es:Wang, Tongshuai (a) Zhang, Mengru (b)
institución:(a) Hongqiao International Institute of Medicine, Shanghai Tongren Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200336, China. (b) Clinical Research Unit Office, Tongren Hospital Shanghai Jiao Tong University School of Medicine, 200336, Shanghai, China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Health literacy and associated factors among adult type 2 diabetic patients in Woldia Comprehensive Specialized Hospital, North-East Ethiopia, 2022.
Health literacy and associated factors among adult type 2 diabetic patients in Woldia Comprehensive Specialized Hospital, North-East Ethiopia, 2022.
Fuente:Frontiers in Public Health
Tipo de trabajo:Revisión
Extracto:
ND RECOMMENDATIONS: The
magnitude of adequate health literacy was low. Ages (18-35) years, ages (36-50)
years, being male, not experiencing depression symptoms, not experiencing
anxiety, and being literate were significantly associated with adequate health
literacy. Health professionals should regularly implement health education
programs for diabetic patients and communities, focusing on females, older
adults, the illiterate, and those experiencing depression and anxiety.
Claves:Ethiopia, Woldia, diabetes, health literacy, magnitude
institución:(a) Department of Biomedical Sciences, College of Medicine and Health Sciences, Wollo University, Dessie, Ethiopia. (b) Department of Surgical Nursing, College of Medicine and Health Sciences, Wollo University, Dessie, Ethiopia.
Conflicto:The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
