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The increasing number of Open Access articles widens the reading offer
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While most of the selected texts belong to original articles,
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The Causal Role of Thyroid Hormones in Bipolar Disorders: A Two-Sample Mendelian Randomization Study.
The Causal Role of Thyroid Hormones in Bipolar Disorders: A Two-Sample Mendelian Randomization Study.
Fuente:Endocrinology, Diabetes & Metabolism
Extracto:
These findings highlight the protective
role of FT4 and the potentially harmful effect of elevated FT3 in Type 1 bipolar
disorder, highlighting the need for further research on thyroid hormone levels as
a potential treatment strategy for Type 1 bipolar disorder.
institución:(a) Department of Public Health Sciences, University of Chicago, Chicago, Illinois, USA. (b) Interdisciplinary Scientist Training Program, University of Chicago, Chicago, Illinois, USA.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Risk factors and prediction model for low-birth-weight infants born to women with gestational diabetes mellitus.
Risk factors and prediction model for low-birth-weight infants born to women with gestational diabetes mellitus.
Fuente:Frontiers in Public Health
Tipo de trabajo:Revisión
Extracto:
It helps
pregnancy clinics to identify the risk of low birth weight in newborns promptly,
in addition to glycemic control and weight management for pregnant women with
GDM, and should improve the appropriate treatment plan for pregnant women with
higher risk, to provide personalized and precise treatment for pregnant women
with GDM and improve infant outcomes.
institución:(a) School of Nursing, Fujian Medical University, Fujian Province, China. (b) Fujian Maternity and Child Health Hospital, College of Clinical Medicine for Obstetrics & Gynecology and Pediatrics, Fujian Medical University, Fuzhou, Fujian, China.
Conflicto:The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
Tracing links between micronutrients and type 2 diabetes risk: the singular role of selenium.
Tracing links between micronutrients and type 2 diabetes risk: the singular role of selenium.
Fuente:Frontiers in Endocrinology
Extracto:
Our
study presents novel evidence of a positive correlation between selenium intake
and T2D risk, underscoring the importance of micronutrients in diabetes
prevention and treatment strategies. Further research is necessary to confirm
these findings and to clarify the specific biological mechanisms through which
selenium influences diabetes risk.
Claves:Mendelian randomization, causality, micronutrients, multivariate analysis, selenium, type 2 diabetes
institución:(a) First Clinical Medical College of Guangzhou University of Chinese Medicine, Guangzhou, China. (b) Guangzhou University of Chinese Medicine Huizhou Hospital, Huizhou, China.
Conflicto:The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
Obesity-related renal dysfunction: gender-specific influence of visceral adiposity and early impact of metabolic and bariatric surgery.
Obesity-related renal dysfunction: gender-specific influence of visceral adiposity and early impact of metabolic and bariatric surgery.
Fuente:Frontiers in Endocrinology
Extracto:
Our results are consistent with previous
findings on the positive impact of MBS on renal function and suggest a more
prominent impact of visceral adiposity on GFR in females.
Autor/es:Popa, Miruna Maria (a) Sirbu, Anca Elena (b)
institución:(a) Department of Endocrinology, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania. (b) Department of Endocrinology and Diabetes, Elias Emergency University Hospital, Bucharest, Romania.
Conflicto:The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
Exploration of physical activity, sedentary behavior and insulin level among short sleepers.
Exploration of physical activity, sedentary behavior and insulin level among short sleepers.
Fuente:Frontiers in Endocrinology
Extracto:
Overall, our analysis demonstrates that in short sleepers, an
increased level of work and recreational activity is beneficial to control the
insulin level, and more sedentary time is harmful. However, this association
might be discrepant in different sexes and different levels of lipid indices.
Claves:NHANES, physical activity, sedentary behavior, serum insulin, short sleepers
institución:(a) School of Public Health and Preventive Medicine, Faculty of Medicine, Nursing & Health Sciences, Monash University, Melbourne, VIC, Australia. (b) Division of Sports Science and Physical Education, Tsinghua University, Beijing, China.
Conflicto:The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
Enhanced joint pain in diabetic patients with knee osteoarthritis is associated with increased synovitis, synovial immune cell infiltration, and erythrocyte extravasation.
Enhanced joint pain in diabetic patients with knee osteoarthritis is associated with increased synovitis, synovial immune cell infiltration, and erythrocyte extravasation.
Fuente:Frontiers in Endocrinology
Extracto:
The
study suggests that increased OA progression and pain severity in patients with
DM result from more pronounced synovitis and synovial vascular leakage and
increased infiltration of macrophages and mast cells.
institución:(a) Department of Trauma, Hand and Reconstructive Surgery, Experimental Trauma Surgery, Jena University Hospital, Friedrich Schiller University, Jena, Germany. (b) Institute of Physiology 1/Neurophysiology, Jena University Hospital, Friedrich Schiller University, Jena, Germany.
Conflicto:The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. The author(s) declared that they were an editorial board member of Frontiers, at the time of submission. This had no impact on the peer review process and the final decision.
Clinical care guidance in patients with diabetes and metabolic dysfunction-associated steatotic liver disease
Clinical care guidance in patients with diabetes and metabolic dysfunction-associated steatotic liver disease
Fuente:Hepatology Communications
Tipo de trabajo:Consenso
Extracto:
Therefore, the Taiwan Association for the Study of the Liver
(TASL), Taiwanese Association of Diabetes Educators, and Diabetes Association of
the Republic of China (Taiwan) collaboratively completed the first guidance in
patients with diabetes and MASLD, which provides practical recommendations for
patient care.
Cita:Hepatol Commun 2024 Nov 1; 8 (11)
Autor/es:Huang, Jee-Fu (a) Chang, Tien-Jyun (b)
institución:(a) Hepatobiliary Division, Department of Internal Medicine, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan. (b) Graduate Institute of Clinical Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan.
Conflicto:Jee-Fu Huang: consultant of Roche, Gilead, Sysmex, and Aligos. Speaker for Abbvie, BMS, Gilead, Merck, Sysmex, and Roche. Chung-Feng Huang: speaker for Abbvie, BMS, Bayer, Gilead, Merck, and Roche. Chin-Sung Kuo: investigators of clinical trials sponsored by Novo Nordisk and AstraZeneca. Wan-Long Chuang: consultant of Gilead, AbbVie, BMS, PharmaEssentia, and Aligos; Speaker for Gilead, AbbVie, BMS, and PharmaEssentia. Ming-Lung Yu:...
Research grant from Abbott, BMS, Merck, and Gilead; Consultant of Abbvie, Abbott, Ascletis, BMS, Merck, Gilead, and Roche; Speaker for Abbvie, Abbott, BMS, Merck, Gilead, and IPSEN. The remaining authors have no conflicts to report.
Extracto:
Potentially effective
measures to overcome intolerance encompasses carefully objective targeted dose
escalation, prescription of fixed dose combination, microbiome modulators and
prebiotics, in addition to use of extended release formulations.
Cita:Medicine (Baltimore) 2024 Oct 25; 103 (43) : e40221.
Autor/es:Potentially effective
measures to overcome intolerance encompasses carefully objective targeted dose
escalation, prescription of fixed dose combination, microbiome modulators and
prebiotics, in addition to use of extended release formulations.
institución:Potentially effective
measures to overcome intolerance encompasses carefully objective targeted dose
escalation, prescription of fixed dose combination, microbiome modulators and
prebiotics, in addition to use of extended release formulations.
Conflicto:The authors have no funding and conflicts of interest to disclose.
Representation of Native Hawaiian and Pacific Islander Individuals in Clinical Trials.
Representation of Native Hawaiian and Pacific Islander Individuals in Clinical Trials.
Fuente:Jama Network Open
Tipo de trabajo:Estudio clínico
Extracto:
AND RELEVANCE: In this
cross-sectional study, limited documentation and participation of Native Hawaiian
and Pacific Islander individuals in clinical trials for drug products with top
sales forecasts was found. This is especially concerning because Native Hawaiian
and Pacific Islander individuals have a higher risk than other racial groups for
type 2 diabetes, cancer, and several other conditions the products examined in
this study treat. Given the importance of enrolling Native Hawaiian and Pacific
Islander participants in clinical trials, sites should be established in key
geographic regions, such as Hawai'i, and postmarket studies should be conducted
within Native Hawaiian and Pacific Islander populations.
Cita:JAMA Netw Open 2024 Oct 1; 7 (10) : e2442204.
Autor/es:Taira, Deborah A (a) Ranken, Mona Shing (b)
institución:(a) Daniel K. Inouye College of Pharmacy, University of Hawai'i at Hilo. (b) The Queen's Medical Center, Honolulu, Hawai'i.
Conflicto:Conflict of Interest Disclosures: Dr Taira reported receiving grants from the National Institutes of Health (NIH) National Institute of General Medical Sciences (NIGMS) during the conduct of the study and grants from the US Food and Drug Administration (FDA) outside the submitted work. Dr Ranken reported receiving personal fees and grants from the FDA outside the submitted work. Dr Davis...
reported receiving grants from the NIH NIGMS during the conduct of the study and grants from the FDA outside the submitted work. Dr Hermosura reported receiving grants from the FDA outside the submitted work. Dr Sentell reported receiving grants from the FDA outside the submitted work. Ms Takata reported receiving grants from the FDA outside the submitted work. Mr Tengan reported receiving grants from the FDA outside the submitted work. Dr T. Seto reported receiving grants from the NIH NIGMS during the conduct of the study and grants from the FDA outside the submitted work. No other disclosures were reported.
Long-Term Effect of TIMP3 Gene Expression on Thyroid Cancer: A Cure Model Analysis.
Long-Term Effect of TIMP3 Gene Expression on Thyroid Cancer: A Cure Model Analysis.
Fuente:Asian Pacific Journal of Cancer Prevention Apjcp
Tipo de trabajo:Estudio de cohortes
Extracto:
TIMP3 expression has a
protective effect on cure probability in thyroid cancer patients, even though it
does not appear to affect short-term survival. This study suggests that targeting
TIMP3 may offer promise for thyroid cancer and may be a potential biomarker for
thyroid cancer prognosis.
Cita:Asian Pac J Cancer Prev 2024 Oct 1; 25 (10) : 3627-3634.
Autor/es:Dindarloo, Mohammad Mehdi (a) Fendereski, Afsaneh (b)
institución:(a) Department of Epidemiology and Biostatistics, School of Health, Mazandaran University of Medical Sciences, Sari, Iran. (b) Department of Epidemiology and Biostatistics, School of Health, Mazandaran University of Medical Sciences, Sari, Iran.
Profiling of five urinary exosomal miRNAs for the differential diagnosis of patients with diabetic kidney disease and focal segmental glomerulosclerosis.
Profiling of five urinary exosomal miRNAs for the differential diagnosis of patients with diabetic kidney disease and focal segmental glomerulosclerosis.
Fuente:Plos One
Extracto:
Specific miRNAs, particularly miR-21, miR-30a, miR-196a,
and miR-200a, might play a role in the pathogenesis of kidney diseases and could
potentially serve as biomarkers to distinguish between FSGS and DKD patients.
Cita:PLoS One 2024; 19 (10) : e0312470.
Autor/es:Trabulus, Sinan (a) Zor, Mehmet Seyit (b)
institución:(a) Division of Nephrology, Department of Internal Medicine, Cerrahpasa Medical Faculty, Istanbul University-Cerrahpasa, Istanbul, Turkey. (b) Department of Molecular Biology and Genetics, Faculty of Science and Letters, Istanbul Technical University, Istanbul, Turkey.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Prevalence and factors associated with peripheral neuropathy in a setting of retail pharmacies in Malaysia-A cross-sectional study.
Prevalence and factors associated with peripheral neuropathy in a setting of retail pharmacies in Malaysia-A cross-sectional study.
Fuente:Plos One
Extracto:
It is crucial for healthcare
providers to proactively screen for peripheral neuropathy, particularly in
high-risk populations, to prevent potential complications.
Cita:PLoS One 2024; 19 (10) : e0307093.
Autor/es:Ching, Siew Mooi (a) Lee, Kai Wei (b)
institución:(a) Department of Family Medicine, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, Serdang, Selangor, Malaysia. (b) Department of Medical Sciences, School of Healthcare and Medical Sciences, Sunway University, Bandar Sunway, Malaysia.
Conflicto:Authors are required to disclose financial or non-financial interests that are directly or indirectly related to the work submitted for publication.
The role of mitochondrial DNA copy number in autoimmune disease: a bidirectional two sample mendelian randomization study.
The role of mitochondrial DNA copy number in autoimmune disease: a bidirectional two sample mendelian randomization study.
Fuente:Frontiers in Immunology
Extracto:
Our study revealed a potential causal relationship between mtDNA copy number and
ADs, indicating that these markers may be relevant in exploring new therapeutic
approaches.
Claves:GWAS, Mendelian randomization, autoimmune disease, causal association, mitochondrial DNA copy number
Cita:Front Immunol 2024; 15 : 1409969.
Autor/es:Liu, Zhekang (a) Fu, Qingan (b)
institución:(a) Rheumatology and Immunology Department, The Second Affiliated Hospital of Nanchang University, Nanchang, Jiangxi, China. (b) Cardiovascular Medicine Department, The Second Affiliated Hospital of Nanchang University, Nanchang, Jiangxi, China.
Conflicto:The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
Dietary acid load adopts the effect of ApoB ins/del genetic variant (rs11279109) on obesity trait, cardiovascular markers, lipid profile, and serum leptin level among patients with diabetes: a cross-sectional study.
Dietary acid load adopts the effect of ApoB ins/del genetic variant (rs11279109) on obesity trait, cardiovascular markers, lipid profile, and serum leptin level among patients with diabetes: a cross-sectional study.
Fuente:Scientific Reports
Extracto:
Further studies are needed to investigate and confirm these findings.
institución:(a) Department of Nutrition, School of Public Health, Iran University of Medical Sciences, Tehran, Iran. (b) Department of nutrition, Dietetics and Food, School of Clinical Sciences at Monash Health, Monash University, Clayton, Australia.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Recommendations for early identification of heart failure in patients with diabetes
Recommendations for early identification of heart failure in patients with diabetes
Fuente:Swiss Medical Weekly
Tipo de trabajo:Consenso
Extracto:
To address
this issue in Switzerland, experts from the Swiss Society of Endocrinology and
Diabetology, the Swiss Society of Cardiology and the General Internal Medicine
specialty met and prepared a consensus report including a simple diagnostic
algorithm for use in everyday practice.
Cita:Swiss Med Wkly 2024 Oct 9; 154 : 4000.
Autor/es:Paul, Matthias (a) Eggerschwiler, Arnold (b)
institución:(a) Heart Centre Lucerne, Luzerner Kantonsspital (LUKS), Lucerne, Switzerland. (b) General Practice, Medbase AG, Lucerne, Switzerland.
Prevalence of Chronic Kidney Disease and Associated Factors among the Diabetic and Prediabetic Population in the Bandare-Kong Cohort Study; A Population-Based Study.
Prevalence of Chronic Kidney Disease and Associated Factors among the Diabetic and Prediabetic Population in the Bandare-Kong Cohort Study; A Population-Based Study.
Fuente:Archives of Iranian Medicine
Tipo de trabajo:Estudio de cohortes
Extracto:
The study emphasizes the importance of early detection and
management of CKD risk factors, particularly among high-risk individuals, to
mitigate CKD progression and associated complications. By addressing modifiable
risk factors, proactive screening, and enhanced awareness, significant strides
can be made in reducing CKD burden and improving patient outcomes.
institución:(a) Endocrinology and Metabolism Research Center, Hormozgan University of Medical Sciences, Bandar Abbas, Iran. (b) Molecular Medicine Research Center, Hormozgan Health Institute, Hormozgan University of Medical Sciences, Bandar Abbas, Iran.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Global trends and emerging topics related to triglyceride-glucose index: A bibliometric analysis and visualization from 2000 to 2024.
Global trends and emerging topics related to triglyceride-glucose index: A bibliometric analysis and visualization from 2000 to 2024.
Fuente:Medicine
Extracto:
Overall, China leads TyG index
research, focusing on its connections to insulin sensitivity, body mass index,
and hyperuricemia, while the index's diagnostic and prognostic significance for
nonalcoholic fatty liver disease and cardiovascular diseases represents an
expanding research frontier.
Cita:Medicine (Baltimore) 2024 Oct 4; 103 (40) : e39916.
Autor/es:Ye, Yusong (a) Huang, Shu (b)
institución:(a) Department of Gastroenterology, the Affiliated Hospital of Southwest Medical University, Luzhou, China. (b) Nuclear Medicine and Molecular Imaging Key Laboratory of Sichuan Province, Luzhou, China.
Conflicto:The authors have no funding and conflicts of interest to disclose.
Transcriptome-wide Mendelian randomization during CD4(+) T cell activation reveals immune-related drug targets for cardiometabolic diseases.
Transcriptome-wide Mendelian randomization during CD4(+) T cell activation reveals immune-related drug targets for cardiometabolic diseases.
Fuente:Nature Communications
Extracto:
This study provides
evidence to support immune-to-metabolic disease connections, and prioritises
immune-mediated drug targets for cardiometabolic diseases.
Cita:Nat Commun 2024 Oct 28; 15 (1) : 9302.
Autor/es:Wu, Xueyan (a) Ying, Hui (b)
institución:(a) Department of Endocrine and Metabolic Diseases, Shanghai Institute of Endocrine and Metabolic Diseases, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. (b) Shanghai National Clinical Research Center for Endocrine and Metabolic Diseases, Key Laboratory for Endocrine and Metabolic Diseases of the National Health Commission of the PR China, Shanghai National Center for Translational Medicine, Shanghai Digital Medicine Innovation Center, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Conflicto:T.R.G. receives funding from Biogen and GSK for research not represented in this manuscript.