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Association between protein intake and sources in mid-pregnancy and the risk of gestational diabetes mellitus.
Association between protein intake and sources in mid-pregnancy and the risk of gestational diabetes mellitus.
Fuente:Bmc Pregnancy and Childbirth
Tipo de trabajo:Orientaciones y guía
Extracto:
The intake of total protein and animal protein, especially eggs, dairy products,
and fish, can reduce the risk of GDM while consuming unprocessed red meat
increases the risk. There is no significant association between the intakes of
plant protein, processed meat, and poultry meat and the occurrence of GDM. The
results of this study are expected to provide a basis for precise nutritional
education, health guidance during pregnancy, and early prevention of GDM.
Cita:BMC Pregnancy Childbirth 2025 Mar 6; 25 (1) : 240.
Autor/es:Wang, Rui (a) Jin, Xingyi (b)
institución:(a) Key Laboratory of Environmental Medicine and Engineering of Ministry of Education, Department of Nutrition and Food Hygiene, School of Public Health, Southeast University, Nanjing, 210009, China. (b) Key Laboratory of Environmental Medicine and Engineering of Ministry of Education, Department of Nutrition and Food Hygiene, School of Public Health, Southeast University, Nanjing, 210009, China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Atherogenic index of plasma, high sensitivity C-reactive protein and incident diabetes among middle-aged and elderly adults in China
Atherogenic index of plasma, high sensitivity C-reactive protein and incident diabetes among middle-aged and elderly adults in China
Fuente:Cardiovascular Diabetology
Tipo de trabajo:Estudio de cohortes
Extracto:
This cohort suggests combined effects and mutual
mediation between the AIP and hsCRP on incident diabetes in China. Our findings
provide clinical implications for monitoring and managing AIP and hsCRP levels to
mitigate the development of diabetes.
Claves:Atherogenic index of plasma, C-reactive protein, Diabetes, Inflammation, Middle-aged and older adults
Cita:Cardiovasc Diabetol 2025 Mar 5; 24 (1) : 103.
Autor/es:Wang, Tongshuai (a) Zhang, Mengru (b)
institución:(a) Hongqiao International Institute of Medicine, Shanghai Tongren Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200336, China. (b) Clinical Research Unit Office, Tongren Hospital Shanghai Jiao Tong University School of Medicine, 200336, Shanghai, China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Health literacy and associated factors among adult type 2 diabetic patients in Woldia Comprehensive Specialized Hospital, North-East Ethiopia, 2022.
Health literacy and associated factors among adult type 2 diabetic patients in Woldia Comprehensive Specialized Hospital, North-East Ethiopia, 2022.
Fuente:Frontiers in Public Health
Tipo de trabajo:Revisión
Extracto:
ND RECOMMENDATIONS: The
magnitude of adequate health literacy was low. Ages (18-35) years, ages (36-50)
years, being male, not experiencing depression symptoms, not experiencing
anxiety, and being literate were significantly associated with adequate health
literacy. Health professionals should regularly implement health education
programs for diabetic patients and communities, focusing on females, older
adults, the illiterate, and those experiencing depression and anxiety.
Claves:Ethiopia, Woldia, diabetes, health literacy, magnitude
institución:(a) Department of Biomedical Sciences, College of Medicine and Health Sciences, Wollo University, Dessie, Ethiopia. (b) Department of Surgical Nursing, College of Medicine and Health Sciences, Wollo University, Dessie, Ethiopia.
Conflicto:The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
Understanding the link between ALDH2 genotypes and diabetes.
Understanding the link between ALDH2 genotypes and diabetes.
Fuente:Frontiers in Endocrinology
Tipo de trabajo:Estudio de cohortes
Extracto:
Our findings revealed that East Asian
men with the ALDH2 GG genotype had an increased risk of diabetes compared to
those with the GA/AA genotype, particularly among individuals with a BMI < 24.
Interestingly, increased adiposity, especially abdominal fat, emerged as a
potential mediator rather than alcohol consumption. Thus, individuals with the GG
genotype, even with a relatively normal BMI, may benefit from regular
moderate-intensity exercise and dietary interventions aimed at managing waist
circumference.
Claves:aldehyde dehydrogenase, body mass index (BMI), interaction effect, type 2 diabetes, waist circumference (WC)
institución:(a) Department of Endocrinology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China. (b) Hubei Provincial Clinical Research Center for Diabetes and Metabolic Disorders, Wuhan, China.
Conflicto:The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
Preliminary quantitative analysis of renal sinus fat dysfunction in T2DM patients using MRI fat fraction and R2* mapping.
Preliminary quantitative analysis of renal sinus fat dysfunction in T2DM patients using MRI fat fraction and R2* mapping.
Fuente:Frontiers in Endocrinology
Extracto:
Mean RSF FF and R2* were
significantly associated with T2DM, and mean RSF FF was the independent risk
factor of T2DM. This finding indicates the hypertrophy of adipocytes and
excessive iron deposition and hypoxia in RSF, which may represent dysfunction of
RSF for T2DM.
Claves:fat dysfunction, magnetic resonance imaging, radiomarker, renal sinus fat, type 2 diabetes mellitus
institución:(a) Department of Radiology, the First Affiliated Hospital of Dalian Medical University, Dalian, China. (b) Department of Radiology, the First Affiliated Hospital of Dalian Medical University, Dalian, China.
Conflicto:The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
Epidemiology and burden of adult chronic pancreatitis in South Australia: a 20-year data linkage study.
Epidemiology and burden of adult chronic pancreatitis in South Australia: a 20-year data linkage study.
Fuente:Bmj Open
Extracto:
CP is a significant burden on the SA healthcare
system and was more prevalent and more burdensome in Indigenous adults. CP
consumes a disproportionate level of public health services. Our findings support
further research and preventive efforts, particularly in the Indigenous
population.
institución:(a) School of Public Health, The University of Adelaide, Adelaide, South Australia, Australia. (b) Department of Surgery, Flinders Medical Centre, Bedford Park, Australia.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Claves:Diabetes & endocrinology, Health Care Costs, Hepatobiliary tumours, Hepatology, Randomised Controlled Trial
Cita:BMJ Open 2025 Mar 6; 15 (3) : e088043.
Autor/es:Buchanan, Ryan M (a) Reinson, Tina (b)
institución:(a) University of Southampton Faculty of Medicine, Southampton, UK ryan.buchanan@soton.ac.uk. (b) University Hospital Southampton NHS Foundation Trust, Southampton, UK.
Conflicto:Competing interests: TR received a one-off consultancy fee from Echosens LTD in 2023. Other authors have no other conflicts of interest to declare.
institución:(a) Department of Biomedical and Clinical Sciences, Linköping University, Linkoping, Sweden. (b) Department of Medicine, Huddinge, Karolinska Institutet, Stockholm, Sweden.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Variations in sex differences in major cardiometabolic risk factors by age and menopause status: results from the UK Biobank.
Variations in sex differences in major cardiometabolic risk factors by age and menopause status: results from the UK Biobank.
Fuente:Open Heart
Extracto:
Effective
public health policy is required to address suboptimal risk factor prevalence,
treatment and control in both sexes. Targeted interventions may be warranted to
address dyslipidaemia among women at older ages.
Claves:cardiovascular disease, prevention, risk factors, sex differences, treatment
institución:(a) The George Institute for Global Health, University of New South Wales, Sydney, New South Wales, Australia RKelly@georgeinstitute.org.au. (b) School of Medicine, University of Tasmania, Hobart, Tasmania, Australia.
Conflicto:Competing interests: MW has been a recent consultant to Freeline. All other authors have no relationships relevant to the contents of this paper to disclose.
Identification of plasma proteomic markers underlying polygenic risk of type 2 diabetes and related comorbidities.
Identification of plasma proteomic markers underlying polygenic risk of type 2 diabetes and related comorbidities.
Fuente:Nature Communications
Extracto:
Our results are available via an
interactive portal ( https://public.cgr.astrazeneca.com/t2d-pgs/v1/ ).
Cita:Nat Commun 2025 Mar 3; 16 (1) : 2124.
Autor/es:Loesch, Douglas P (a) Garg, Manik (b)
institución:(a) Centre for Genomics Research, Discovery Sciences, BioPharmaceuticals R&D, AstraZeneca, Cambridge, UK. douglas.loesch@astrazeneca.com. (b) Centre for Genomics Research, Discovery Sciences, BioPharmaceuticals R&D, AstraZeneca, Cambridge, UK.
Conflicto:Competing interests: D.P.L., M.G., D.M., D.V., X.J., I.A.G., S.P., J.O., A.N. and D.S.P. are employees of AstraZeneca and may hold AstraZeneca stock options. B.B.S. and H.R. are employees of Biogen and may hold stock options. C.D.W. is an employee of Janssen Pharmaceuticals, a Johnson & Johnson company, and may hold stock options. R.R.H. reports personal fees from Anji Pharmaceuticals, AstraZeneca...
and Novartis. R.J.M. received research support and honoraria from Abbott, American Regent, Amgen, AstraZeneca, Bayer, Boehringer Ingelheim, Boston Scientific, Cytokinetics, Fast BioMedical, Gilead, Innolife, Eli Lilly, Medtronic, Medable, Merck, Novartis, Novo Nordisk, Pfizer, Pharmacosmos, Relypsa, Respicardia, Roche, Rocket Pharmaceuticals, Sanofi, Verily, Vifor, Windtree Therapeutics, and Zoll. M.I. is a trustee of the Public Health Genomics (PHG) Foundation, a member of the Scientific Advisory Board of Open Targets and has research collaborations with Nightingale Health and Pfizer which are unrelated to this study. F.A.M. received consulting fees from Janssen. S.D.W. received grants from Amgen, AstraZeneca, Daiichi Sankyo, Eisai, Janssen, Merck, and Pfizer, and consulting fees from AstraZeneca, Boston Clinical Research Institute, Icon Clinical, and Novo Nordisk. M.S.S. received research grant support through Brigham and Women’s Hospital from Abbott, Amgen, Anthos Therapeutics, AstraZeneca, Boehringer Ingelheim, Daiichi-Sankyo, Eisai, Intarcia, Ionis, Merck, Novartis, and Pfizer, and consulting for Althera, Amgen, Anthos Therapeutics, AstraZeneca, Beren Therapeutics, Boehringer Ingelheim, Bristol-Myers Squibb, Dr. Reddy’s Laboratories, Fibrogen, Intarcia, Merck, Moderna, Novo Nordisk, Precision BioSciences, and Silence Therapeutics. The remaining authors declare no competing interests.
Development and validation of a clinical prediction model for dialysis-requiring acute kidney injury following heart transplantation: a single-center study from China.
Development and validation of a clinical prediction model for dialysis-requiring acute kidney injury following heart transplantation: a single-center study from China.
Fuente:Bmc Surgery
Tipo de trabajo:Estudio clínico
Extracto:
Dialysis-requiring AKI following HT is
associated with poor clinical prognosis. The prediction model, comprising six
indicators, is capable of predicting dialysis-requiring AKI following HT. This
prediction model holds promise in assisting both patients and clinicians in
forecasting postoperative renal failure, thereby improving clinical management.
CLINICAL TRIAL NUMBER: Not applicable.
institución:(a) Department of Cardiovascular Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, 1277 Jiefang Ave, Wuhan, 430022, China. (b) Department of Cardiovascular Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, 1277 Jiefang Ave, Wuhan, 430022, China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Gender differences in the relationship between cardiometabolic index and all-cause and specific mortality in the United States adults: a national study.
Gender differences in the relationship between cardiometabolic index and all-cause and specific mortality in the United States adults: a national study.
Fuente:Frontiers in Endocrinology
Extracto:
There were gender differences in the correlation between CMI and
all-cause mortality, cardiovascular mortality, and diabetes mortality in the
adult population. The findings indicated that adult females with elevated CMI
levels were at an elevated risk of mortality from all causes, cardiovascular
disease, and diabetes. At the same time, there were no significant associations
in adult males.
Claves:NHANES, all-cause mortality, cardiometabolic index, gender differences, specific mortality
institución:(a) Institute of Cardiovascular Disease of Integrated Traditional Chinese and Western Medicine, Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai, China. (b) Branch of National Clinical Research Center for Chinese Medicine Cardiology, Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Conflicto:The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
A Virtual Cardiometabolic Health Program Among African Immigrants in the US
A Virtual Cardiometabolic Health Program Among African Immigrants in the US
Fuente:Jama Network Open
Tipo de trabajo:Estudio clínico aleatorizado
Extracto:
AND RELEVANCE: Trial findings
indicate that interventions incorporating cultural adaptation and virtual
components could help address CMH disparities in this population. TRIAL
REGISTRATION: ClincalTrials.gov Identifier NCT05144737.
Cita:JAMA Netw Open 2025 Mar 3; 8 (3) : e2462559.
Autor/es:Ogungbe, Oluwabunmi (a) Hinneh, Thomas (b)
institución:(a) Johns Hopkins University School of Nursing, Baltimore, Maryland. (b) Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland.
Conflicto:Conflict of Interest Disclosures: Dr Spaulding reported consulting for Corrie Health outside the submitted work. No other disclosures were reported.
Association of clinical biomarker-based biological age and aging trajectory with cardiovascular disease and all-cause mortality in Chinese adults
Association of clinical biomarker-based biological age and aging trajectory with cardiovascular disease and all-cause mortality in Chinese adults
Fuente:Bmc Public Health
Tipo de trabajo:Estudio de cohortes
Extracto:
Accelerated BA aging is associated with a higher
risk of CVD and mortality, whereas decelerated aging is associated with a lower
risk compared to normal aging. Those persistently at high aging levels are at the
highest risk for both CVD and death; conversely, it is the act of lowering and
continually maintaining a reduced aging state that effectively mitigates these
risks.
institución:(a) National Human Genetic Resources Center, National Research Institute for Family Planning, Beijing, China. (b) National Human Genetic Resources Sharing Service Platform, Beijing, China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Analysis of the kidney failure risk equation implementation in routine clinical practice and health inequalities in chronic kidney disease care
Analysis of the kidney failure risk equation implementation in routine clinical practice and health inequalities in chronic kidney disease care
Fuente:Bmc Nephrology
Tipo de trabajo:Estudio de cohortes
Extracto:
KFRE could be calculated for less than half
of people due to lack of albuminuria testing. Focus should be given to improving
albuminuria testing and inequities identified to allow wider implementation of
KFRE.
institución:(a) School of Cardiovascular and Metabolic Health, University of Glasgow, Glasgow, Scotland. heather.walker.2@glasgow.ac.uk. (b) Robertson Centre for Biostatistics, University of Glasgow, Glasgow, Scotland.
Conflicto:Declarations. Consent for publication: Not applicable. Competing interests: PBM reports lecture honoraria from Astrazeneca, Pharmacomsos, Bayer, Astellas, GSK and Boehringer Ingelheim outside the submitted work. The other authors have no potential conflicts of interest to declare. Ethics approval and consent to participate: Delegated research ethics approval was granted for linkage to National Health Service (NHS) patient data by the Local...
Privacy and Advisory Committee at NHS Greater Glasgow and Clyde. Cohorts and de-identified linked data were prepared by the West of Scotland Safe Haven Research Database at NHS Greater Glasgow and Clyde (IRAS Project ID 321198, REC reference 22/WS/1063, West of Scotland REC 4, https://www.hra.nhs.uk/planning-and-improving-research/application-summaries/research-summaries/west-of-scotland-safe-haven-research-database/ .). Conflicts of interest: The other authors have no potential conflicts of interest to declare. Rights retention statement: For the purpose of open access, the author(s) has applied a Creative Commons Attribution (CC BY) licence to any Author Accepted Manuscript version arising from this submission.
Confounder adjustment in observational studies investigating multiple risk factors: a methodological study.
Confounder adjustment in observational studies investigating multiple risk factors: a methodological study.
Fuente:Bmc Medicine
Tipo de trabajo:Revisión
Extracto:
There is
substantial variation in the methods for confounder adjustment among studies
investigating multiple risk factors. Mutual adjustment was the most commonly
adopted method, which might lead to overadjustment bias and misleading effect
estimates. Future research should avoid indiscriminately including all risk
factors in a multivariable model to prevent inappropriate adjustment.
institución:(a) Department of Epidemiology and Biostatistics, Xiangya School of Public Health, Central South University, Changsha, China. (b) Department of Epidemiology and Biostatistics, Xiangya School of Public Health, Central South University, Changsha, China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Association between cardiometabolic index and biological ageing among adults: a population-based study.
Association between cardiometabolic index and biological ageing among adults: a population-based study.
Fuente:Bmc Public Health
Extracto:
CMI is positively correlated with biological ageing in adults in the
United States. Prospective studies with larger sample sizes are required to
validate our findings.
institución:(a) Department of Laboratory Medicine, Huashan Hospital, Fudan University, Shanghai, China. (b) Department of Forensic Medicine and Laboratory Medicine, Jining Medical University, Jining, China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Long-term trajectory of estimated glomerular filtration rate in ambulatory patients with type 2 diabetes and heart failure: clinical insights and prognostic implications.
Long-term trajectory of estimated glomerular filtration rate in ambulatory patients with type 2 diabetes and heart failure: clinical insights and prognostic implications.
Fuente:Cardiovascular Diabetology
Extracto:
This study offers novel insights into long-term
renal function trajectories in patients with HF and T2D and identifies key
clinical factors associated with accelerated renal decline. Future research is
warranted to validate these results in larger, more diverse cohorts and to
explore potential therapeutic interventions.
Cita:Cardiovasc Diabetol 2025 Mar 5; 24 (1) : 104.
Autor/es:Julián, Maria Teresa (a) Codina, Pau (b)
institución:(a) Department of Endocrinology and Nutrition and Heart Failure Clinic, Hospital Germans Trias i Pujol, Badalona, Spain. (b) Heart Failure Clinic and Cardiology Department, Hospital Germans Trias i Pujol, Badalona, Spain.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Circulating mitochondrial DNA signature in cardiometabolic patients.
Circulating mitochondrial DNA signature in cardiometabolic patients.
Fuente:Cardiovascular Diabetology
Extracto:
Patients with HF and diabetes have an altered circulating
mtDNA signature characterised by higher cell-free mtDNA and lower mtDNA ratio,
whereas cellular mtDNA remains unaffected. Cell-free mtDNA and mtDNA ratio are
associated with impaired response to exercise, higher systemic inflammation and
increased congestion. Circulating mitochondrial profile could be a new biomarker
of mitochondrial status in cardiometabolic diseases.
institución:(a) Department of Clinical and Experimental Medicine, University of Pisa, Via Roma 67, 56124, Pisa, Italy. (b) Center for Translational and Experimental Cardiology (CTEC), Department of Cardiology, University Hospital Zurich, University of Zurich, Zurich, Switzerland.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
