Association between blood urea nitrogen levels and diabetic retinopathy in diabetic adults in the United States (NHANES 2005-2018).

Association between blood urea nitrogen levels and diabetic retinopathy in diabetic adults in the United States (NHANES 2005-2018).

Fuente:Frontiers in Endocrinology

Extracto: BUN levels were related with an increased prevalence of DR, particularly in individuals with BUN >20 mg/dl. These findings highlight the significance of BUN level in assessing the risk of DR.

Claves:NHANES, blood urea nitrogen, complication, diabetes, diabetic retinopathy

Cita:Front Endocrinol (Lausanne) 2024; 15 : 1403456.

Autor/es:Du, Kejie (a)
Luo, Wenjuan (b)

institución:(a) Department of Ophthalmology, The Affiliated Hospital of Qingdao University, Qingdao, China.
(b) Department of Ophthalmology, The Affiliated Hospital of Qingdao University, Qingdao, China.

Conflicto:The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3389/fendo.2024.1403456

Clinicians in the Veterans Health Administration initiate gender-affirming hormone therapy in concordance with clinical guideline recommendations.

Fuente:Frontiers in Endocrinology

Tipo de trabajo:Guía de recomendaciones

Extracto: We observed high concordance between current GAHT initiation practices in VHA and guidelines, particularly for feminizing GAHT. Findings suggest that VHA clinicians are initiating feminizing GAHT in concordance with clinical guidelines. Future work should assess guideline concordance on monitoring and management of GAHT in VHA.

Claves:Veterans Health Administration, clinical guidelines, gender-affirming hormone therapy, guideline concordance, transgender and gender diverse, veterans

Cita:Front Endocrinol (Lausanne) 2024; 15 : 1086158.

Autor/es:Jasuja, Guneet K (a)
Wolfe, Hill L (b)

institución:(a) Center for Healthcare Organization & Implementation Research, Veteran Affairs (VA) Bedford Healthcare System, Bedford, MA, United States.
(b) Section of General Internal Medicine, Boston University Chobanian & Avedisian School of Medicine, Boston, MA, United States.

Conflicto:The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3389/fendo.2024.1086158

Association between maternal and fetal inflammatory biomarkers and offspring weight and BMI during the first year of life in pregnancies with GDM: MySweetheart study.

Fuente:Frontiers in Endocrinology

Extracto: In women with GDM, maternal and fetal inflammatory biomarkers distinctively influenced offspring anthropometry during the first year of life, independent of maternal age, prepregnancy BMI and ethnicity. These results suggest that low-grade inflammation during pregnancy may affect the developing offspring by leading to a decrease in weight and BMI and may have implications for future personalized follow-up of women with GDM and their offspring.

Claves:cord blood CRP, gestational diabetes, maternal pro-inflammatory cytokines, offspring anthropometry, perinatal inflammation

Cita:Front Endocrinol (Lausanne) 2024; 15 : 1333755.

Autor/es:Antoniou, Maria-Christina (a)
Quansah, Dan Yedu (b)

institución:(a) Unit of Pediatric Endocrinology and Diabetology, Pediatric Service, Woman-Mother-Child Department, Lausanne University Hospital, Lausanne, Switzerland.
(b) Obstetric Service, Woman-Mother-Child Department, Lausanne University Hospital, Lausanne, Switzerland.

Conflicto:The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. This study is funded by a project grant from the Swiss National Science Foundation (SNF 32003B_176119) and by an unrestricted educational grant from Novo Nordisk and The Gottfried und Julia Bangerter-Rhyner-Stiftung Foundation. The... funders were not involved in the study design, collection, analysis, interpretation of data, the writing of this article or the decision to submit it for publication.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3389/fendo.2024.1333755

Clinical effectiveness and predictors of response to topiramate plus lifestyle modification in youth with obesity seen in a weight management clinical setting.

Fuente:Frontiers in Endocrinology

Tipo de trabajo:Estudio de cohortes

Extracto: We found that topiramate plus lifestyle modification reduced %BMIp95 and BMI among youth in a weight management clinical setting, and that no baseline characteristics evaluated were associated with response. These results should be considered preliminary given the observational nature of this study, and prospective studies are needed to further characterize clinical effectiveness and identify and confirm potential predictors of response.

Claves:anti-obesity agents, obesity, obesity management, pediatric obesity, topiramate

Cita:Front Endocrinol (Lausanne) 2024; 15 : 1369270.

Autor/es:Bomberg, Eric M (a)
Clark, Justin (b)

institución:(a) Center for Pediatric Obesity Medicine, Department of Pediatrics, University of Minnesota Medical School, Minneapolis, MN, United States.
(b) Division of Endocrinology, Department of Pediatrics, University of Minnesota Medical School, Minneapolis, MN, United States.

Conflicto:EB and CF are or have been site principal investigators and co-investigators for Novo Nordisk. AK engages in unpaid consulting and educational activities for Boehringer Ingelheim, Novo Nordisk, Vivus, and Eli Lilly, and receives donated drug and placebo from Novo Nordisk and Vivus for National Institutes of Diabetes and Digestive and Kidney Diseases NIDDK-funded clinical trials. The remaining authors declare... that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3389/fendo.2024.1369270

The L-shape relationship between hemoglobin, albumin, lymphocyte, platelet score and the risk of diabetic retinopathy in the US population.

Fuente:Frontiers in Endocrinology

Extracto: The HALP score has an L-shaped correlation with the risk of DR, and thus, the HALP score may contribute to the timely intervention of diabetes patients.

Claves:HALP score, NHANES, biomarker, diabetes complication, diabetic retinopathy

Cita:Front Endocrinol (Lausanne) 2024; 15 : 1356929.

Autor/es:Ding, Ranran (a)
Zeng, Yusong (b)

institución:(a) Department of Ophthalmology, Tianjin Medical University General Hospital, Heping District, Tianjin, China.
(b) Tianjin Medical University, Heping District, Tianjin, China.

Conflicto:The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3389/fendo.2024.1356929

Causal effects of hypertensive disorders of pregnancy on future gynecologic tumors: A two-sample Mendelian randomization study.

Causal effects of hypertensive disorders of pregnancy on future gynecologic tumors: A two-sample Mendelian randomization study.

Fuente:Cancer Medicine

Extracto: We discovered no causal relationship between HDPs and ovarian, cervical, endometrial, breast cancer, and uterine fibroids in European populations. However, present analysis did not explore the effect of HDPs on the subtypes of gynecologic tumors across varied ethnic populations, which may require additional research.

Claves:Mendelian randomization, breast cancer, endometrial cancer, hypertensive disorders in pregnancy, preeclampsia

Cita:Cancer Med 2024 May; 13 (10) : e7300.

Autor/es:Zhou, Le (a)
Liu, Xinghui (b)

institución:(a) Department of Gynecology and Obstetrics, West China Second University Hospital, Sichuan University, Chengdu, China.
(b) Key Laboratory of Obstetrics & Gynecologic and Pediatric Diseases and Birth Defects of Ministry of Education, West China Second University Hospital, Sichuan University, Chengdu, China.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe impreso

Idioma:Inglés

País de fuente:EE.UU.

Sitio web:http://dx.doi.org/10.1002/cam4.7300

Admissions by tuberculosis in a regional reference Center. A complex and worrying scenario.

Admissions by tuberculosis in a regional reference Center. A complex and worrying scenario.

Fuente:Revista Medica de Chile

Extracto: In this case series, the diagnosis of TB cases was delayed, scarcely diagnosed by molecular methods, highly concentrated at the hospital level, required admission in a large percentage of cases, and had a high case-fatality rate.

Cita:Rev Med Chil 2023 Jun; 151 (6) : 742-752.

Autor/es:Fica, Alberto (a)
Osorio, Carola (b)

institución:(a) Servicio Medicina Hospital Base de Valdivia, Valdivia, Chile.
(b) Laboratorio de Tuberculosis, Hospital Base de Valdivia, Valdivia, Chile.

Formato:Informe impreso

Idioma:Inglés

País de fuente:Chile

Sitio web:http://dx.doi.org/10.4067/s0034-98872023000600742

Proton-coupled transport mechanism of the efflux pump NorA.

Proton-coupled transport mechanism of the efflux pump NorA.

Fuente:Nature Communications

Extracto: Hence, the two acidic residues serve as a "belt and suspenders" protection mechanism to prevent simultaneous binding of protons and drug that enforce NorA coupling stoichiometry and confer antibiotic resistance.

Cita:Nat Commun 2024 May 27; 15 (1) : 4494.

Autor/es:Li, Jianping (a)
Li, Yan (b)

institución:(a) Department of Chemistry, New York University, New York, NY, USA.
(b) Department of Cell Biology, New York University School of Medicine, New York, NY, USA.

Conflicto:A.K., S.K., D.N.W. and N.J.T. are listed as inventors of a patent application filed by New York University on NorA inhibitors (WO2023014970A2). S.K. is a co-founder and holds equity in Aethon Therapeutics and Revalia Bio; has received consulting fees from Aethon Therapeutics and Black Diamond Therapeutics; has received research funding from Aethon Therapeutics, Argenx BVBA, Black Diamond Therapeutics, and Puretech... Health, all outside of the current work. V.J.T. is an inventor on patents and patent applications filed by NYU, which are currently under commercial license to Janssen Biotech Inc. Janssen Biotech Inc. has provided research funding and other payments associated with the licensing agreement. The remaining authors declare no competing interests.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1038/s41467-024-48759-3

The influence of acute lifestyle changes on NAFLD evolution in a multicentre cohort: a matter of body composition.

The influence of acute lifestyle changes on NAFLD evolution in a multicentre cohort: a matter of body composition.

Fuente:Nutrition & Diabetes

Extracto: The acute lifestyle changes impacted NAFLD evolution via body composition modifications negatively influencing the HCC occurrence.

Cita:Nutr Diabetes 2024 May 27; 14 (1) : 33.

Autor/es:Dallio, Marcello (a)
Sangineto, Moris (b)

institución:(a) Hepatogastroenterology Division, Department of Precision Medicine, University of Campania "Luigi Vanvitelli", Naples, Italy.
(b) University Center for Research and Treatment of Liver Diseases (C.U.R.E.), Liver Unit, University of Foggia, Foggia, Italy.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1038/s41387-024-00294-2

Association between lipid profile and clinical outcomes in COVID-19 patients.

Association between lipid profile and clinical outcomes in COVID-19 patients.

Fuente:Scientific Reports

Extracto: It contributes to the understanding of COVID-19 patient management and emphasizes the need for further investigation into the role of dyslipidemia in influencing COVID-19 prognosis, potentially aiding in refined risk stratification and therapeutic strategies.

Claves:Biomarker, COVID-19 severity, HDL cholesterol, SARS-CoV-2

Cita:Sci Rep 2024 May 27; 14 (1) : 12139.

Autor/es:Ochoa-Ramírez, Luis Antonio (a)
De la Herrán Arita, Alberto Kousuke (b)

institución:(a) Hospital General de Culiacán "Bernardo J. Gastelum", Servicios de Salud de Sinaloa, Culiacán, Sinaloa, Mexico.
(b) Facultad de Medicina, Universidad Autónoma de Sinaloa, Culiacán, Sinaloa, Mexico.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1038/s41598-024-62899-y

Mediation Mendelian randomisation study on the effects of shift work on coronary heart disease and traditional risk factors via gut microbiota.

Mediation Mendelian randomisation study on the effects of shift work on coronary heart disease and traditional risk factors via gut microbiota.

Fuente:Journal of Global Health

Extracto: Our findings suggest a causal effect of JSW on CHD, diabetes, and hypertension. We also found evidence for a significant connection between JSW and alterations in the gut microbiota. Considering that certain microbial taxa mediated the effect of JSW on hypertension risk, targeting gut microbiota through therapeutics could potentially mitigate high risks of hypertension and CHD associated with JSW.

Cita:J Glob Health 2024 May 28; 14 : 04110.

Autor/es:Zhang, Yun (a)
Zhao, Lingyun (b)

institución:Zhang, Yun (a)
Zhao, Lingyun (b)

Conflicto:Disclosure of interest: The authors completed the ICMJE Disclosure of Interest Form (available upon request from the corresponding author) and disclose no relevant interests.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Scotland

Sitio web:http://dx.doi.org/10.7189/jogh.14.04110

Adverse pregnancy outcomes in gestational diabetes mellitus

Adverse pregnancy outcomes in gestational diabetes mellitus

Fuente:Bmj Open

Tipo de trabajo:Revisión sistemática

Extracto: PROSPERO REGISTRATION NUMBER: CRD42020155061.

Claves:diabetes & endocrinology, diabetes in pregnancy, public health, statistics & research methods

Cita:BMJ Open 2024 May 23; 14 (5) : e058625.

Autor/es:Chukwuemeka, Scholarstica (a)
Chivese, Tawanda (b)

institución:(a) School of Pharmacy, University of the Western Cape, Bellville, South Africa.
(b) Qatar University, Doha, Ad Dawhah, Qatar tchivese@qu.edu.qa.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1136/bmjopen-2021-058625

Evaluating the implementation of group empowerment and training (GREAT) for diabetes in South Africa: convergent mixed methods.

Fuente:Bmj Open

Extracto: Key lessons were learnt on how to implement GREAT for diabetes in a middle-income country setting. The findings informed the design of a programme theory using a health system framework. The programme theory will guide further scale-up in each province and scale-out to provinces that have not yet implemented. QUESTION: This study focused on evaluating how to implement GREAT for type 2 diabetes in primary care and to take it to scale in South Africa. FINDING: The findings led to a programme theory on how to successfully implement GREAT for diabetes in the South African context. MEANING: The study demonstrates relevant contextual factors that need to be considered in the implementation of group diabetes education programme in a middle-income country.

Claves:general diabetes, health education, health services, primary care

Cita:BMJ Open 2024 May 23; 14 (5) : e085171.

Autor/es:Mash, Robert James (a)
Schouw, Darcelle (b)

institución:(a) Division of Family Medicine and Primary Care, Stellenbosch University, Cape Town, South Africa rm@sun.ac.za.
(b) Division of Family Medicine and Primary Care, Stellenbosch University, Cape Town, South Africa.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1136/bmjopen-2024-085171

Determinants of COVID-19 severity in Ethiopia

Fuente:Bmj Open

Tipo de trabajo:Estudio multicéntrico

Extracto: Male, older age, diabetes or hypertension comorbidity, COVID-19 vaccination and having inadequate knowledge about COVID-19 were determinant factors of severe COVID-19.

Claves:COVID-19, epidemiology, public health

Cita:BMJ Open 2024 May 23; 14 (5) : e083076.

Autor/es:Tadie, Manayesh Bantie (a)
Yimer, Yimer Seid (b)

institución:(a) PHEM, Ethiopian Public Health Institute, Addis Ababa, Ethiopia manye2116@gmail.com.
(b) Department of Preventive Medicine, School of Public Health, Addis Ababa University, Addis Ababa, Ethiopia.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1136/bmjopen-2023-083076

Effect of needle-free injection on psychological insulin resistance and insulin dosage in patients with type 2 diabetes.

Effect of needle-free injection on psychological insulin resistance and insulin dosage in patients with type 2 diabetes.

Fuente:Frontiers in Endocrinology

Tipo de trabajo:Estudio clínico

Extracto: NFI can improve PIR in patients with T2DM and be used with a smaller dose of insulin aspart 30 while maintaining the same hypoglycemic effect. CLINICAL TRIAL REGISTRATION: https://www.chictr.org.cn/, identifier ChiCTR2400083658.

Claves:blood glucose control, glycemic variability, insulin aspart 30, insulin dosage, needle-free injection, psychological insulin resistance, type 2 diabetes mellitus

Cita:Front Endocrinol (Lausanne) 2024; 15 : 1379830.

Autor/es:Wang, Weiping (a)
Men, Lili (b)

institución:(a) Department of Endocrinology, The First Affiliated Hospital of Dalian Medical University, Dalian, China.
(b) Dalian Key Laboratory of Prevention and Treatment of Metabolic Diseases and the Vascular Complications, The First Affiliated Hospital of Dalian Medical University, Dalian, China.

Conflicto:The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3389/fendo.2024.1379830

The burden and treatment of non-communicable diseases among healthcare workers in sub-Saharan Africa: a multi-country cross-sectional study.

The burden and treatment of non-communicable diseases among healthcare workers in sub-Saharan Africa: a multi-country cross-sectional study.

Fuente:Frontiers in Public Health

Extracto: The prevalence of self-reported chronic disease varied across the four sub-Saharan countries with potentially very low treatment rates. We identified several individual (age, sex, and BMI) and occupational (profession, level of healthcare) factors that influence the odds of NCDs. These factors should be taken into account when developing interventions addressing the burden and management of NCDs among HCWs.

Claves:diabetes, healthcare workers, hypertension, non-communicable diseases, sub-Sahara Africa

Cita:Front Public Health 2024; 12 : 1375221.

Autor/es:Müller, Sophie Alice (a)
Elimian, Kelly (b)

institución:(a) Robert Koch Institute, Berlin, Germany.
(b) Nigeria Centre for Disease Control and Prevention, Abuja, Nigeria.

Conflicto:The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3389/fpubh.2024.1375221

Exercise Across the Phases of Cancer Survivorship

Exercise Across the Phases of Cancer Survivorship

Fuente:Yonsei Medical Journal

Tipo de trabajo:Revisión

Extracto: Although additional research is warranted, existing evidence is sufficient to integrate exercise into clinical oncology practice and cancer survivorship programs.

Claves:Exercise, adjuvant chemotherapy, cancer survivors, neoplasms

Cita:Yonsei Med J 2024 Jun; 65 (6) : 315-323.

Autor/es:An, Ki-Yong (a)
Min, Jihee (b)

institución:(a) Faculty of Kinesiology, Sport, and Recreation, University of Alberta, Edmonton, AB, Canada.
(b) National Cancer Control Institute, National Cancer Center, Goyang, Korea.

Conflicto:The authors have no potential conflicts of interest to disclose.

Formato:Informe impreso

Idioma:Inglés

País de fuente:Corea del Sur

Sitio web:http://dx.doi.org/10.3349/ymj.2023.0638

Metabolic memory and diabetic retinopathy: Legacy of glycemia and possible steps into future.

Metabolic memory and diabetic retinopathy: Legacy of glycemia and possible steps into future.

Fuente:Indian Journal of Ophthalmology

Extracto: We discuss the challenges in such research.

Cita:Indian J Ophthalmol 2024 Jun 1; 72 (6) : 796-808.

Autor/es:Sheemar, Abhishek (a)
Bellala, Keerthi (b)

institución:(a) Moorfields Eye Hospital, NHS Foundation Trust, London, UK.
(b) Anant Bajaj Retina Institute, LV Prasad Eye Institute, Vishakhapatnam, Andhra Pradesh, India.

Formato:Informe impreso

Idioma:Inglés

País de fuente:India

Sitio web:http://dx.doi.org/10.4103/IJO.IJO_2563_23

Prior COVID-19 infection among newly diagnosed tuberculosis patients in a tertiary care center in Tehran: A case-control study.

Fuente:Immunity, Inflammation and Disease

Extracto: There seems to be an association between prior history of COVID-19 and a future diagnosis of TB partially linked to the severity of disease. The findings of the current study may serve as a basis for further studies to determine the need for and efficacy of measures to follow-up COVID-19 patients at an increased risk for developing TB.

Claves:COVID‐19, Tocilizumab, corticosteroid, prevention, pulmonary, reactivation, risk, tuberculosis

Cita:Immun Inflamm Dis 2024 May; 12 (5) : e1275.

Autor/es:Semnani, Kiavash (a)
Sohrabi, Marjan (b)

institución:(a) Tehran University of Medical Sciences School of Medicine, Tehran, Iran.
(b) Department of Infectious Diseases, Tehran University of Medical Sciences, Imam Khomeini Hospital Complex, Tohid Squre, Tehran, Iran.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe impreso

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1002/iid3.1275

Ratio of Red Blood Cell Distribution Width to Albumin Level and Risk of Mortality.

Ratio of Red Blood Cell Distribution Width to Albumin Level and Risk of Mortality.

Fuente:Jama Network Open

Tipo de trabajo:Estudio de cohortes

Extracto: AND RELEVANCE: In this cohort study, a higher baseline RAR was associated with an increased risk of all-cause and cause-specific mortality in the general population. These findings suggest that RAR may be a simple, reliable, and inexpensive indicator for identifying individuals at high risk of mortality in clinical practice.

Cita:JAMA Netw Open 2024 May 1; 7 (5) : e2413213.

Autor/es:Hao, Meng (a)
Jiang, Shuai (b)

institución:(a) Department of Vascular Surgery, Shanghai Key Laboratory of Vascular Lesion Regulation and Remodeling, Shanghai Pudong Hospital, Fudan University Pudong Medical Center, Shanghai, China.
(b) Greater Bay Area Institute of Precision Medicine (Guangzhou), Fudan University, Nansha District, Guangzhou, China.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:EE.UU.

Sitio web:http://dx.doi.org/10.1001/jamanetworkopen.2024.13213