Textos Completos Autorizados

Diabetología
SIIC selecciona textos completos de calidad y de reciente publicación en fuentes prestigiosas del mundo indizadas por SIIC Data Bases, capturadas en las mismas colecciones o en diversas bases especializadas.
La creciente cantidad de artículos con Acceso Abierto (Open Access) amplía la oferta de lectura pero a su vez también, entre tanta abundancia, complica al lector en su encuentro con los estudios fundamentales. Para facilitarlo, profesionales biomédicos de SIIC consultan diariamente una profusa cantidad de documentos que nutrirán Textos completos autorizados (TCA).

Las citas de la sección TCA enlazan de manera legal, autorizada y gratuita con los textos completos (full text) publicados en los sitios oficiales de sus respectivas fuentes.

SIIC creó, produjo y opera con exclusividad el software TCA para la interpretación de los diversos campos documentales que integran la estructura de un estudio: especialidad, modalidad del estudio, fuente, fechas de publicación y selección, definición de la fuente, limitaciones de consulta, resumen en castellano, etc.

Si bien la mayoría de los textos seleccionados corresponden a artículos originales, revisiones y guías, los lectores también encontrarán comentarios, entrevistas, notas periodísticas, cartas a autores u otros textos precursores de debates o aclaratorios.

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(escribir en inglés)
 
Ej.1: Adipokines Ej.2: Adipokines or Musculoskeletal
Con la frase exacta
(inglés)

Ej.3: Adipokines and Cardiovascular Systems
Con todas de las palabras
(inglés)

Ej.4: Adipokines and Cardiovascular and Systems
Sin las palabras
(inglés)

Ej.5: not Cardiovascular Systems
BMJ open
Selección SIIC: 21 Noviembre, 2024
BMJ open

Health-related quality of life in adults with metabolic syndrome: a multi-level analysis of family and individual level variation.

Health-related quality of life in adults with metabolic syndrome: a multi-level analysis of family and individual level variation.

Fuente:Bmj Open

Tipo de trabajo:Guía

Extracto: This study revealed the significant influence of gender, as well as the unique characteristics and circumstances of individuals, on the relationship between MetS and HRQoL in a general population with low/middle income.

Claves:DIABETES & ENDOCRINOLOGY, MENTAL HEALTH, PUBLIC HEALTH, Quality of Life

Cita:BMJ Open 2024 Nov 18; 14 (11) : e087870.

Autor/es:Niknam, Mahdieh (a)
Olazadeh, Keyvan (b)

institución:(a) Research Center for Social Determinants of Health, Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
(b) Research Center for Social Determinants of Health, Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1136/bmjopen-2024-087870

BMC nephrology
Selección SIIC: 21 Noviembre, 2024
BMC nephrology

Association between chronic kidney disease and cardiovascular disease risk factors in elderly: results from the first phase of Fasa and Shahedieh cohort studies.

Association between chronic kidney disease and cardiovascular disease risk factors in elderly: results from the first phase of Fasa and Shahedieh cohort studies.

Fuente:Bmc Nephrology

Extracto: Our study showed that more than half of the patients were in stage three CKD, which is an advanced stage of this disease. Diabetes Melitus, hypertension, dyslipidemia, IHD, and myocardial infarction were more prevalent in patients than others. These findings demonstrate the importance of screening for CKD in patients with diabetes mellitus and hypertension. The results also suggest that lifestyle modification and prevention strategies are needed to reduce the burden of CKD and CVD in this population.

Claves:Cardiovascular disease, Chronic kidney disease, Elderly, Fasa cohort study, Yazd health study

Cita:BMC Nephrol 2024 Nov 18; 25 (1) : 413.

Autor/es:Zarshenas, Fatemeh (a)
Dehghan, Azizallah (b)

institución:(a) Noncommunicable Diseases Research Center, Fasa University of Medical Sciences, Fasa, Iran.
(b) Noncommunicable Diseases Research Center, Fasa University of Medical Sciences, Fasa, Iran.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1186/s12882-024-03566-2

BMC public health
Selección SIIC: 21 Noviembre, 2024
BMC public health

Interaction of proteinuria and diabetes on the risk of cardiovascular events: a prospective cohort CKD-ROUTE study.

Interaction of proteinuria and diabetes on the risk of cardiovascular events: a prospective cohort CKD-ROUTE study.

Fuente:Bmc Public Health

Tipo de trabajo:Estudio de cohortes

Extracto: In summary, among participants with CKD stages 2-5, proteinuria and diabetes were found to independently and jointly affect the risk of cardiovascular events. Participants with proteinuria and diabetes had the highest risk of cardiovascular events compared with other groups.

Claves:Cardiovascular disease, Chronic kidney disease, Diabetes, Proteinuria, Urinary protein-to-creatinine ratio

Cita:BMC Public Health 2024 Nov 18; 24 (1) : 3192.

Autor/es:Kishor, Shahi (a)
Chen, Jianrong (b)

institución:(a) Department of Endocrinology and Metabolism, First Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang, 330006, People's Republic of China.
(b) Jiangxi Clinical Research Center for Endocrine and Metabolic Disease, Nanchang, 330006, People's Republic of China.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1186/s12889-024-20715-2

Selección SIIC: 21 Noviembre, 2024

Undiagnosed hypertension and diabetes mellitus in the Tabari cohort: a population-based study.

Undiagnosed hypertension and diabetes mellitus in the Tabari cohort: a population-based study.

Fuente:Bmc Public Health

Tipo de trabajo:Estudio de cohortes

Extracto: Overall, younger participants, those residing in urban areas, those with TC ≥ 200 mg/dL, and those without a positive family history of HTN or DM were at a greater risk of undiagnosed HTN/DM.

Claves:Prevalence, Tabari cohort population, Undiagnosed diabetes mellitus, Undiagnosed hypertension

Cita:BMC Public Health 2024 Nov 18; 24 (1) : 3199.

Autor/es:Moosazadeh, Mahmood (a)
Ebrahimnejad, Pedram (b)

institución:(a) Gastrointestinal Cancer Research Center, Non- Communicable Diseases Research Institute, Mazandaran University of Medical Sciences, Mazandaran, Iran.
(b) Department of Pharmaceutics, Pharmaceutical Sciences Research Center, Hemoglobinopathy Institute, Mazandaran University of Medical Sciences, Sari, Iran.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1186/s12889-024-20701-8

Cardiovascular diabetology
Selección SIIC: 21 Noviembre, 2024
Cardiovascular diabetology

Assessing coronary artery stenosis exacerbated impact on left ventricular function and deformation in metabolic syndrome patients by 3.0 T cardiac magnetic resonance imaging.

Assessing coronary artery stenosis exacerbated impact on left ventricular function and deformation in metabolic syndrome patients by 3.0 T cardiac magnetic resonance imaging.

Fuente:Cardiovascular Diabetology

Extracto: Besides traditional biochemical indicators, incorporating CAS assessment and CMR assessment of the LV into routine evaluations ensures a more holistic approach to managing MetS patients. Timely intervention of CAS is crucial for improving cardiovascular outcomes in this high-risk population.

Claves:Cardiac magnetic resonance imaging, Coronary artery stenosis, Global peak strain, Metabolic syndrome

Cita:Cardiovasc Diabetol 2024 Nov 18; 23 (1) : 414.

Autor/es:Jiang, Yi-Ning (a)
Gao, Yue (b)

institución:(a) Department of Radiology, West China Hospital, Sichuan University, 37# Guo Xue Xiang, Chengdu, 610041, Sichuan, China.
(b) Department of Radiology, West China Hospital, Sichuan University, 37# Guo Xue Xiang, Chengdu, 610041, Sichuan, China.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1186/s12933-024-02492-9

Selección SIIC: 21 Noviembre, 2024

Associations of baseline and changes in the triglyceride glucose-weight adjusted waist index and cardiovascular disease risk: evidence from middle-aged and older individuals.

Associations of baseline and changes in the triglyceride glucose-weight adjusted waist index and cardiovascular disease risk: evidence from middle-aged and older individuals.

Fuente:Cardiovascular Diabetology

Extracto: These findings were corroborated through extensive sensitivity analyses.

Claves:Baseline, Cardiovascular disease, China Health and Retirement Longitudinal Study, Dynamic changes, Triglyceride-glucose index, Weight-adjusted waist index

Cita:Cardiovasc Diabetol 2024 Nov 18; 23 (1) : 415.

Autor/es:Duan, Chenglin (a)
Lyu, Meng (b)

institución:(a) Department of Cardiovascular, Guang'anmen Hospital, China Academy of Chinese Medical Sciences, Beijing, China. 20230941377@bucm.edu.cn.
(b) Graduate school, Beijing University of Chinese Medicine, Beijing, China. 20230941377@bucm.edu.cn.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1186/s12933-024-02511-9

Medicine
Selección SIIC: 21 Noviembre, 2024
Medicine

Metabolic syndrome among patients with type 2 diabetes in Jordan: A cross-sectional study.

Metabolic syndrome among patients with type 2 diabetes in Jordan: A cross-sectional study.

Fuente:Medicine

Extracto: It is recommended that healthcare providers counsel patients on the importance of maintaining physical activity, smoking cessation, and adherence to a diet regimen.

Cita:Medicine (Baltimore) 2024 Nov 15; 103 (46) : e40602.

Autor/es:Hyassat, Dana (a)
Al-Refai, Ala'a (b)

institución:(a) The National Center for Diabetes, Endocrinology, and Genetics, The University of Jordan, Amman, Jordan.
(b) The National Center for Diabetes, Endocrinology, and Genetics, The University of Jordan, Amman, Jordan.

Conflicto:The authors have no funding and conflict of interest to disclose.

Formato:Informe impreso

Idioma:Inglés

País de fuente:EE.UU.

Sitio web:http://dx.doi.org/10.1097/MD.0000000000040602

Selección SIIC: 21 Noviembre, 2024

Triglyceride-glucose index and risk of all-cause and cardiovascular mortality in patients with cardiovascular disease: Analysis from 1999 to 2018 NHANES data.

Triglyceride-glucose index and risk of all-cause and cardiovascular mortality in patients with cardiovascular disease: Analysis from 1999 to 2018 NHANES data.

Fuente:Medicine

Extracto: This will be helpful in accurately evaluating the risk and prognosis of CVD patients, and ultimately in developing more precise and personalized treatment and management strategies.

Cita:Medicine (Baltimore) 2024 Nov 15; 103 (46) : e40534.

Autor/es:Ding, Wenlong (a)
Fang, Caoyang (b)

institución:(a) Department of Cardiology, Xuancheng Hospital Affiliated to Wannan Medical College (Xuancheng People 's Hospital), Xuancheng, Anhui, China.
(b) Department of Emergency, First Affiliated Hospital of University of Science and Technology of China, Anhui Provincial Hospital, Hefei, Anhui, China.

Conflicto:The authors have no funding and conflicts of interest to disclose.

Formato:Informe impreso

Idioma:Inglés

País de fuente:EE.UU.

Sitio web:http://dx.doi.org/10.1097/MD.0000000000040534

Selección SIIC: 21 Noviembre, 2024

Risk factors for left ventricular remodeling after myocardial infarction

Risk factors for left ventricular remodeling after myocardial infarction

Fuente:Medicine

Tipo de trabajo:Metanálisis

Extracto: The current study provides evidence indicating that diabetes, the site of MI, cystatin C, B-type natriuretic peptide, and creatine kinase-myocardial band are the primary risk factors for LVR after MI. Recognizing and addressing these modifiable risk factors is crucial for the development of effective preventive and treatment strategies.

Cita:Medicine (Baltimore) 2024 Nov 15; 103 (46) : e40496.

Autor/es:Xu, Baozhu (a)
Li, Wenhui (b)

institución:(a) Health Management Center, Xiang'an Hospital of Xiamen University, Xiamen, China.
(b) Health Management Center, Xiang'an Hospital of Xiamen University, Xiamen, China.

Conflicto:The authors have no funding and conflicts of interest to disclose.

Formato:Informe impreso

Idioma:Inglés

País de fuente:EE.UU.

Sitio web:http://dx.doi.org/10.1097/MD.0000000000040496

Nature communications
Selección SIIC: 21 Noviembre, 2024
Nature communications

Profiling of insulin-resistant kidney models and human biopsies reveals common and cell-type-specific mechanisms underpinning Diabetic Kidney Disease.

Profiling of insulin-resistant kidney models and human biopsies reveals common and cell-type-specific mechanisms underpinning Diabetic Kidney Disease.

Fuente:Nature Communications

Extracto: This study provides a rich data resource to direct future studies in elucidating underlying kidney signalling pathways and potential therapeutic targets in DKD.

Cita:Nat Commun 2024 Nov 19; 15 (1) : 10018.

Autor/es:Lay, Abigail C (a)
Tran, Van Du T (b)

institución:(a) Bristol Renal, Bristol Medical School, University of Bristol, Bristol, UK.
(b) Division of Cardiovascular Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1038/s41467-024-54089-1

Scientific reports
Selección SIIC: 21 Noviembre, 2024
Scientific reports

Associations between serum mineral concentrations and mortality by renal function in the Ludwigshafen Risk and Cardiovascular Health Study.

Associations between serum mineral concentrations and mortality by renal function in the Ludwigshafen Risk and Cardiovascular Health Study.

Fuente:Scientific Reports

Tipo de trabajo:Guía

Extracto: To reduce mortality risk, it's important to regularly monitor serum mineral and phosphate concentrations as well as renal function, especially in cardiovascular patients with compromised renal function.

Claves:All-cause mortality, Cardiometabolic risk, Cardiovascular mortality, Minerals, Renal function

Cita:Sci Rep 2024 Nov 19; 14 (1) : 28581.

Autor/es:Moissl, Angela P (a)
Delgado, Graciela E (b)

institución:(a) Institute of Nutritional Sciences, Friedrich Schiller University Jena, Dornburger Straße 25, 07743, Jena, Germany.
(b) Competence Cluster for Nutrition and Cardiovascular Health (nutriCARD) Halle-Jena-Leipzig, Jena, Germany.

Conflicto:Declarations Competing interests Marcus E. Kleber and Winfried März are employed with SYNLAB Germany. The other authors do not report any conflict of interest. Informed consent Written informed consent was obtained from all participants involved in the study. Ethical statement The study was approved by the Ethics Committee of the “Landesärztekammer Rheinland-Pfalz” (837.255.97 (1394)) and conducted in accordance with the... masnoticias.gif

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1038/s41598-024-79575-w

BMC endocrine disorders
Selección SIIC: 21 Noviembre, 2024
BMC endocrine disorders

Risk of Hepatocellular Carcinoma with Glucagon-like Peptide-1 receptor agonist treatment in patients

Risk of Hepatocellular Carcinoma with Glucagon-like Peptide-1 receptor agonist treatment in patients

Fuente:Bmc Endocrine Disorders

Tipo de trabajo:Revisión sistemática

Extracto: GLP-1 RAs may offer protective benefits against HCC in T2DM patients compared to insulin or no GLP-1 RAs, but not significantly over other antidiabetic medications. This review indicates the need for further randomized controlled trials to clarify the role of GLP-1 RAs in HCC risk mitigation and to explore their mechanistic pathways in liver disease management.

Claves:Glucagon-like Peptide-1 receptor agonists, Hepatocellular carcinoma, Meta-analysis, Type 2 diabetes mellitus

Cita:BMC Endocr Disord 2024 Nov 18; 24 (1) : 246.

Autor/es:Shabil, Muhammed (a)
Khatib, Mahalaqua Nazli (b)

institución:(a) University Center for Research and Development, Chandigarh University, Mohali, Punjab, India.
(b) Medical Laboratories Techniques Department, AL-Mustaqbal University, Hillah, Babil, 51001, Iraq.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1186/s12902-024-01775-2

BMC neurology
Selección SIIC: 21 Noviembre, 2024
BMC neurology

Comparison of functional outcome after intracerebral hemorrhage in patients with or without end stage renal disease on hemodialysis: a propensity-score matched study.

Comparison of functional outcome after intracerebral hemorrhage in patients with or without end stage renal disease on hemodialysis: a propensity-score matched study.

Fuente:Bmc Neurology

Extracto: ICH patients with ESRD on HD had significantly higher in-hospital mortality and lower rate of obesity than propensity score matched controls, suggesting a survival benefit from obesity. ICH score ≥ 3 is an independent predictor for poor outcomes in both ESRD and non-ESRD groups.

Claves:End stage renal disease, Hemodialysis, Intracerebral hemorrhage, Mortality, Obesity

Cita:BMC Neurol 2024 Nov 18; 24 (1) : 451.

Autor/es:Tsutsumi, Kotaro (a)
Nguyen, Matthew (b)

institución:(a) Department of Neurology, University of California, Irvine, 200 S. Manchester Ave. Suite 206, Orange, CA, 92868, USA. ktsutsum@hs.uci.edu.
(b) School of Medicine, University of California, Irvine, Orange, CA, USA.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1186/s12883-024-03932-5

The journal of maternal-fetal & neonatal medicine the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians

Selección SIIC: 21 Noviembre, 2024

The journal of maternal-fetal & neonatal medicine the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians

Causal association between vitamin D and gestational diabetes mellitus: a two-sample Mendelian randomization study.

Causal association between vitamin D and gestational diabetes mellitus: a two-sample Mendelian randomization study.

Fuente:The Journal of Maternal-fetal & Neonatal Medicine The Official Journal of The European Association of Perinatal Medicine, The Federation of Asia and Oceania Perinatal Societies, The International Society of Perinatal Obstetricians

Extracto: We observed no assosiation between genetically predicted vitamin D and the risk of GDM, implying that insufficient vitamin D may do not confer an increased susceptibility to GDM.

Claves:GDM, GWAS, MR, Vitamin D, causal effects

Cita:J Matern Fetal Neonatal Med 2024 Dec; 37 (1) : 2427760.

Autor/es:Zhang, Pei (a)
Hu, XiaoHong (b)

institución:(a) Department of Gynecology and Obstetrics, Affiliated Maternal and Child Health Care Hospital of Nantong University, Nantong, P.R. China.
(b) Department of Gynecology and Obstetrics, Affiliated Maternal and Child Health Care Hospital of Nantong University, Nantong, P.R. China.

Formato:Informe impreso

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1080/14767058.2024.2427760

The journal of maternal-fetal & neonatal medicine the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians

Selección SIIC: 21 Noviembre, 2024

The journal of maternal-fetal & neonatal medicine the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians

Exploring the relationship between maternal Continuous Glucose Monitoring "time in range" and fetal abdominal circumference in pregnant women with Type 1 Diabetes.

Exploring the relationship between maternal Continuous Glucose Monitoring "time in range" and fetal abdominal circumference in pregnant women with Type 1 Diabetes.

Fuente:The Journal of Maternal-fetal & Neonatal Medicine The Official Journal of The European Association of Perinatal Medicine, The Federation of Asia and Oceania Perinatal Societies, The International Society of Perinatal Obstetricians

Tipo de trabajo:Estudio de cohortes

Extracto: There was no cross-sectional relationship between TIR and fetal AC in the third trimester of pregnancy but first trimester TIR did predict fetal AC in late pregnancy.

Claves:Continuous Glucose Monitoring, Pregnancy, Type 1 diabetes, fetal abdominal circumference, time in range

Cita:J Matern Fetal Neonatal Med 2024 Dec; 37 (1) : 2428391.

Autor/es:Woon, Liesel (a)
Glyn, Tessa (b)

institución:(a) Department of Obstetrics and Gynaecology, Royal Women's Hospital, Parkville, Australia.
(b) Department of Diabetes and Endocrinology, Southmead Hospital, North Bristol NHS Trust, Bristol, UK.

Formato:Informe impreso

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1080/14767058.2024.2428391

Hematology (Amsterdam, Netherlands)

Selección SIIC: 21 Noviembre, 2024

Hematology (Amsterdam, Netherlands)

Neutrophil count and reduced risk of venous thromboembolism: a Mendelian randomization study.

Neutrophil count and reduced risk of venous thromboembolism: a Mendelian randomization study.

Fuente:Hematology (amsterdam, Netherlands)

Extracto: According to our MR study, we found evidence suggesting that higher neutrophil count linked to a lower risk of VTE. These findings may provide potential therapeutic targets for the prevention and treatment of VTE.

Claves:Mendelian randomization, Neutrophil, genome-wide association studies, neutrophil extracellular traps, venous thromboembolism

Cita:Hematology 2024 Dec; 29 (1) : 2428481.

Autor/es:Zhao, Jiaojie (a)
Zhang, Weixun (b)

institución:(a) Beijing Chest Hospital, Capital Medical University & Beijing Tuberculosis and Thoracic Tumor Research Institute; Beijing, China.
(b) Department of Thoracic Surgery, China-Japan Friendship Hospital, Beijing, China.

Formato:Informe impreso

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1080/16078454.2024.2428481

European review for medical and pharmacological sciences
Selección SIIC: 14 Noviembre, 2024
European review for medical and pharmacological sciences

Results of endovascular interventions for peripheral arterial diseases on the targeted arterial segments.

Results of endovascular interventions for peripheral arterial diseases on the targeted arterial segments.

Fuente:European Review For Medical and Pharmacological Sciences

Tipo de trabajo:Estudio de cohortes

Extracto: Endovascular interventions in this study were an effective and minimally invasive therapeutic option for PADs, with satisfactory results in 98.28%. Further studies, including the long-term and clinical outcomes after EVIs for PADs, are required.

Cita:Eur Rev Med Pharmacol Sci 2024 Oct; 28 (20) : 4451-4460.

Autor/es:Chinaliyev, A (a)
Saparbayev, S (b)

institución:Chinaliyev, A (a)
Saparbayev, S (b)

Formato:Informe impreso

Idioma:Inglés

País de fuente:Italia

Sitio web:http://dx.doi.org/10.26355/eurrev_202410_36868

Orphanet journal of rare diseases
Selección SIIC: 14 Noviembre, 2024
Orphanet journal of rare diseases

Molecular analysis of inherited disorders of cornification in polish patients show novel variants and functional data and provokes questions on the significance of secondary findings.

Molecular analysis of inherited disorders of cornification in polish patients show novel variants and functional data and provokes questions on the significance of secondary findings.

Fuente:Orphanet Journal of Rare Diseases

Extracto: Our results show that NGS-based analysis is an effective MeDOC diagnostic tool. The Polish MeDOC patients are heterogenic, however recurrent variants are present. The novel variants and high number of TGM1 and SPINK5 copy number variations give further insight into molecular pathology of MeDOC. We show that secondary variants in MeDOC-related genes are present in a significant group of patients, which should be further investigated in the context of phenotype modifiers. Finally, we provide novel RNA and lipid data that characterise molecularly MeDOC epidermis.

Claves:Genes, Genodermatoses, Ichthyoses, MeDOC, PPK, RNAseq, Secondary findings, Variants

Cita:Orphanet J Rare Dis 2024 Nov 5; 19 (1) : 413.

Autor/es:Wertheim-Tysarowska, Katarzyna (a)
Osipowicz, Katarzyna (b)

institución:(a) Department of Medical Genetics, Institute of Mother and Child, Warsaw, 01-211, Poland. katarzyna.wertheim@imid.med.pl.
(b) Department of Dermatology, Immunodermatology and Venereology, Medical University of Warsaw, Warsaw, 02-008, Poland.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1186/s13023-024-03395-4

Acta oncologica (Stockholm, Sweden)
Selección SIIC: 14 Noviembre, 2024
Acta oncologica (Stockholm, Sweden)

The impact of age on clinicopathological features and treatment results in patients with localised prostate cancer receiving definitive radiotherapy.

The impact of age on clinicopathological features and treatment results in patients with localised prostate cancer receiving definitive radiotherapy.

Fuente:Acta Oncologica (stockholm, Sweden)

Extracto: Although patients over 70 years have higher risk factors and comorbidities, their bDFS, PCSS, and toxicities were comparable to those of patients aged < 70 years.

Cita:Acta Oncol 2024 Nov 5; 63 : 858-866.

Autor/es:Onal, Cem (a)
Guler, Ozan Cem (b)

institución:(a) Department of Radiation Oncology, Baskent University Faculty of Medicine Adana Dr. Turgut Noyan Research and Treatment Center, Adana, Turkey; Department of Radiation Oncology, Baskent University Faculty of Medicine, Ankara, Turkey. hcemonal@hotmail.com.
(b) Department of Radiation Oncology, Baskent University Faculty of Medicine Adana Dr. Turgut Noyan Research and Treatment Center, Adana, Turkey.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suecia

Sitio web:http://dx.doi.org/10.2340/1651-226X.2024.40759

Frontiers in endocrinology
Selección SIIC: 14 Noviembre, 2024
Frontiers in endocrinology

Analysis of risk factors for painful diabetic peripheral neuropathy and construction of a prediction model based on Lasso regression.

Analysis of risk factors for painful diabetic peripheral neuropathy and construction of a prediction model based on Lasso regression.

Fuente:Frontiers in Endocrinology

Extracto: 33.2% of DPN patients had PDPN in Hunan Province, China. Peripheral artery disease, duration of diabetes, smoking, and HBA1c are risk factors for PDPN in patients with type 2 diabetes. The prediction model is based on the above factors, which can well predict the probability of PDPN.

Claves:LASSO regression, diabetic, painful diabetic peripheral neuropathy, risk, type 2 diabetes mellitus

Cita:Front Endocrinol (Lausanne) 2024; 15 : 1477570.

Autor/es:Yu, Zikai (a)
Zhao, Sue (b)

institución:(a) The Affiliated Changsha Central Hospital, Hengyang Medical School, University of South China, Changsha, China.
(b) The Affiliated Changsha Central Hospital, Hengyang Medical School, University of South China, Changsha, China.

Conflicto:The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3389/fendo.2024.1477570

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