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Surveillance of surgical site infections in orthopedic prosthetic surgery: a tool for identifying risk factors and improving clinical practice.
Surveillance of surgical site infections in orthopedic prosthetic surgery: a tool for identifying risk factors and improving clinical practice.
Fuente:Journal of Preventive Medicine and Hygiene
Extracto:
Although based on a small number of patients, these
results are encouraging, especially considering that the patients had an average
ASA score of more than 2 and a high BMI. However, to further reduce the risk of
infection, improved hygiene measures have now been implemented in the operating
room and the antibiotic prophylaxis protocol has been updated to take into
account the potential for MRSA colonization.
Claves:Antimicrobial prophylaxis, Knee and Hip prosthesis, Surgical Site Infection
Cita:J Prev Med Hyg 2024 Jun; 65 (2) : E273-E277.
Autor/es:Porretto, Martina (a) Parente, Flavio (b)
institución:(a) Health Directorate Galliera Hospital, Genoa, Italy. (b) Department of Health Sciences, University of Genoa, Genoa, Italy.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Correlation of dietary flavonoid intake with chronic bronchitis, emphysema, and asthma in U.S. adults: A large, national, cross-sectional study.
Correlation of dietary flavonoid intake with chronic bronchitis, emphysema, and asthma in U.S. adults: A large, national, cross-sectional study.
Fuente:Plos One
Extracto:
Higher dietary flavonoid intake was associated
with lower chronic respiratory risk in adult U.S. men. Also 29 dietary flavonoid
components have an overall health effect on respiratory health. Glycitein and
Eriodictyol may have potential health effects on the respiratory system. 1500
mg/day may be the Tolerable Upper Intake Level of dietary flavonoids for
respiratory health in U.S. adults.
Cita:PLoS One 2024; 19 (10) : e0309310.
Autor/es:Sun, Mengshi (a) Ding, Qin (b)
institución:(a) Department of Gynecological Tumor Surgery, Hubei Cancer Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China. (b) Department of Gastroenterology, Hubei Cancer Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Female and diabetes are risk factors for alpha-fetoprotein and protein induced by vitamin K absence or antagonist-II negative in hepatocellular carcinoma.
Female and diabetes are risk factors for alpha-fetoprotein and protein induced by vitamin K absence or antagonist-II negative in hepatocellular carcinoma.
Fuente:Medicine
Extracto:
Imaging is crucial for screening liver cancer in these
patients.
Cita:Medicine (Baltimore) 2024 Oct 18; 103 (42) : e40100.
Autor/es:Shi, Yanhui (a) Yang, Hongli (b)
institución:(a) Cheeloo College of Medicine, Shandong University, Jinan, China. (b) Department of Gastroenterology, The First Affiliated Hospital of Shandong First Medical University & Shandong Provincial Qianfoshan Hospital, Jinan, China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Identification and validation of core genes associated with polycystic ovary syndrome and metabolic syndrome.
Identification and validation of core genes associated with polycystic ovary syndrome and metabolic syndrome.
Fuente:Medicine
Extracto:
This gene may serve as a potential diagnostic marker and therapeutic target for
both conditions.
Cita:Medicine (Baltimore) 2024 Oct 18; 103 (42) : e40162.
Autor/es:Ling, Shaohua (a) Huang, Liying (b)
institución:(a) Reproductive Medicine Center, The Affiliated Hospital of Youjiang Medical University for Nationalities, Baise, China. (b) Reproductive Medicine Center, The Southwest Affiliated Hospital of Youjiang Medical University for Nationalities, Baise, China.
Conflicto:The authors declare that the research was conducted without any commercial or financial relationships that could be construed as a potential conflict of interest.
Mitochondrial diabetes presenting with spontaneous abortion and ketoacidosis onset
Mitochondrial diabetes presenting with spontaneous abortion and ketoacidosis onset
Fuente:Medicine
Tipo de trabajo:Revisión
Extracto:
This case
underscores the significance of genetic testing and family history in diagnosing
MDM and the need for increased awareness among clinicians to prevent
misdiagnosis.
Cita:Medicine (Baltimore) 2024 Oct 18; 103 (42) : e40039.
Autor/es:Wu, Baoyuan (a) Tao, Yubing (b)
institución:(a) Medical Science and Technology Innovation Center, Shandong First Medical University and Shandong Academy of Medical Sciences, Jinan, China. (b) Department of Endocrinology, Xuzhou Central Hospital, Xuzhou, China.
Exploring the causal pathway from gut microbiota to polycystic ovary syndrome: A network Mendelian randomization study.
Exploring the causal pathway from gut microbiota to polycystic ovary syndrome: A network Mendelian randomization study.
Fuente:Medicine
Extracto:
Sellimonas may be a protective factor of PCOS, which can affect the occurrence of
PCOS through BMI, supporting future studies on the importance of addressing
obesity and metabolic issues in preventing and managing PCOS.
Cita:Medicine (Baltimore) 2024 Oct 18; 103 (42) : e40115.
Autor/es:Gao, Xueyan (a) Zhao, Huijuan (b)
institución:Gao, Xueyan (a) Zhao, Huijuan (b)
Conflicto:The authors have no funding and conflicts of interest to disclose.
Effects of phytosterol supplementation on lipid profiles and apolipoproteins
Effects of phytosterol supplementation on lipid profiles and apolipoproteins
Fuente:Medicine
Tipo de trabajo:Metanálisis
Extracto:
Our findings suggest that dietary phytosterols can effectively
promote the reduction of TC, LDL-c, and Apo-B, along with increased high-density
lipoprotein cholesterol in adults.
Cita:Medicine (Baltimore) 2024 Oct 18; 103 (42) : e40020.
Autor/es:Zhang, Yi-Feng (a) Qiao, Wanning (b)
institución:(a) School of Public Health (Shenzhen), Sun Yat-sen University, Shenzhen, Guangdong, China. (b) School of Public Health (Shenzhen), Sun Yat-sen University, Shenzhen, Guangdong, China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Combined detection of serum adiponectin and pregnancy-associated plasma protein A for early prediction of gestational diabetes mellitus.
Combined detection of serum adiponectin and pregnancy-associated plasma protein A for early prediction of gestational diabetes mellitus.
Fuente:Medicine
Extracto:
The combined detection of PAPP-A
and ADP should be utilized in diagnosing GDM to improve pregnancy outcomes for
pregnant women.
Cita:Medicine (Baltimore) 2024 Oct 18; 103 (42) : e40091.
Autor/es:Wang, Xia (a) Sheng, Yajun (b)
institución:(a) Department of Laboratory Medicine, Zhongshan City People's Hospital, Zhongshan, China. (b) Gynaecology of Zhongshan Torch Development Zone People's Hospital, Zhongshan, China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Feasibility and Acceptability of a Self-Guided Digital Family Skills Management Intervention for Children Newly Diagnosed With Type 1 Diabetes: Pilot Randomized Controlled Trial.
Feasibility and Acceptability of a Self-Guided Digital Family Skills Management Intervention for Children Newly Diagnosed With Type 1 Diabetes: Pilot Randomized Controlled Trial.
Fuente:Jmir Formative Research
Tipo de trabajo:Estudio aleatorizado y controlado
Extracto:
In this study, we found that a self-guided digital family support
intervention initiated at the time of a child's T1D diagnosis was largely
feasible and acceptable. Overall, rates of participation and module completion
were similar to or higher than other self-guided digital prevention interventions
for mental and physical health outcomes. Self-guided digital programs addressing
family management skills may help prevent challenges common with T1D management
and can decrease cost, increase access, and add flexibility compared to
traditional interventions. TRIAL REGISTRATION: ClinicalTrials.gov NCT03720912;
https://clinicaltrials.gov/study/NCT03720912.
Claves:RCT, acceptability, caregiver, children, communication, diabetes, family dynamics, family support, feasibility, intervention, psychosocial, randomized controlled trial, self-guided, type 1 diabetes, web-based intervention, well-being
Cita:JMIR Form Res 2024 Oct 21; 8 : e59246.
Autor/es:Hughes Lansing, Amy (a) Cohen, Laura B (b)
institución:(a) Department of Psychological Science, University of Vermont, Burlington, VT, United States. (b) Department of Psychological Science, University of Vermont, Burlington, VT, United States.
Development and Testing of a Mobile App for Management of Gestational Diabetes in Nepal: Protocol for a User-Centered Design Study and Exploratory Randomized Controlled Trial.
Development and Testing of a Mobile App for Management of Gestational Diabetes in Nepal: Protocol for a User-Centered Design Study and Exploratory Randomized Controlled Trial.
Fuente:Jmir Research Protocols
Tipo de trabajo:Estudio aleatorizado y controlado
Extracto:
App-based lifestyle
interventions for GDM management are not common in LMICs, where GDM prevalence is
rapidly increasing. This proof-of-concept trial will provide valuable insights
into the potential of leveraging mHealth app-based platforms for GDM
self-management in LMICs. TRIAL REGISTRATION: ClinicalTrials.gov NCT04198857;
https://clinicaltrials.gov/study/NCT04198857. INTERNATIONAL REGISTERED REPORT
IDENTIFIER (IRRID): DERR1-10.2196/59423.
Claves:Nepal, South Asia, gestational diabetes mellitus, low- and middle-income country, mHealth, maternal and child health, mobile health, mobile phone, pregnancy, self-management
Cita:JMIR Res Protoc 2024 Oct 21; 13 : e59423.
Autor/es:Berube, Lauren T (a) Shrestha, Archana (b)
institución:(a) Public Health Nutrition Program, Department of Epidemiology, New York University School of Global Public Health, New York, NY, United States. (b) Institute for Implementation Science and Health, Kathmandu, Nepal.
Toward a Clinical Decision Support System for Monitoring Therapeutic Antituberculosis Medical Drugs in Tanzania (Project TuberXpert): Protocol for an Algorithm' Development and Implementation.
Toward a Clinical Decision Support System for Monitoring Therapeutic Antituberculosis Medical Drugs in Tanzania (Project TuberXpert): Protocol for an Algorithm' Development and Implementation.
Fuente:Jmir Research Protocols
Extracto:
At the end of the TuberXpert
project, Tanzania will possess a new tool to help the practitioners with the
adaptation of drug dosage targeting complicated TB cases (TB or HIV, TB or
diabetes mellitus, and TB or malnutrition). This automated system will be
validated and used in the field and will be proposed to other countries affected
by endemic TB. In addition, this approach will serve as proof of concept
regarding the feasibility and suitability of CDSS-assisted TDM for further
anti-TB drugs in TB-burdened areas deprived of TDM experts, including second-line
treatments considered important to monitor. INTERNATIONAL REGISTERED REPORT
IDENTIFIER (IRRID): DERR1-10.2196/58720.
Claves:TDM, Tanzania, clinical decision support system, clinical pharmacology, mobile phone, model-informed precision dosing software, pharmacometrics, therapeutic drug monitoring, tuberculosis
Cita:JMIR Res Protoc 2024 Oct 21; 13 : e58720.
Autor/es:Thoma, Yann (a) Cathignol, Annie E (b)
institución:(a) School of Engineering and Management Vaud, HES-SO University of Applied Sciences and Arts Western Switzerland, Yverdon-les-Bains, Switzerland. (b) School of Engineering and Management Vaud, HES-SO University of Applied Sciences and Arts Western Switzerland, Yverdon-les-Bains, Switzerland.
Association between physical activity and diabetes control: multiple cross-sectional studies and a prospective study in a population-based, Swiss cohort.
Association between physical activity and diabetes control: multiple cross-sectional studies and a prospective study in a population-based, Swiss cohort.
Fuente:Bmj Open
Extracto:
No differences in PA
levels were found between participants with controlled and uncontrolled T2DM.
Claves:epidemiologic studies, general diabetes, preventive medicine
Cita:BMJ Open 2024 Oct 21; 14 (10) : e078929.
Autor/es:VonLanthen, Gaël (a) Marques-Vidal, Pedro (b)
institución:(a) Faculty of Biology and Medicine, University of Lausanne, Lausanne, Switzerland. (b) Medicine, Internal Medicine, Lausanne University Hospital (CHUV), Lausanne, Switzerland.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Do relationships between ambient temperature and serious adverse health outcomes vary among users of different antidiabetes drugs? A retrospective cohort study of US Medicaid beneficiaries with type 2 diabetes.
Do relationships between ambient temperature and serious adverse health outcomes vary among users of different antidiabetes drugs? A retrospective cohort study of US Medicaid beneficiaries with type 2 diabetes.
Fuente:Bmj Open
Extracto:
We identified some antidiabetes drug class-specific and
agent-specific differences in the relationship between ambient temperature and
untoward glycaemic but not arrhythmogenic, safety outcomes.
Claves:climate change, diabetes & endocrinology, epidemiology, public health
Cita:BMJ Open 2024 Oct 21; 14 (10) : e085139.
Autor/es:Leonard, Charles E (a) Bogar, Kacie (b)
institución:(a) Center for Real-World Effectiveness and Safety of Therapeutics, Department of Biostatistics, Epidemiology, and Informatics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA celeonar@pennmedicine.upenn.edu. (b) Center for Clinical Epidemiology and Biostatistics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Conflicto:Competing interests: CEL is a Special Government Employee of the US Food and Drug Administration. CEL consults for Novo Nordisk and TriNetX. CEL recently received an honorarium from the American College of Clinical Pharmacy Foundation, University of Florida and Ancora Education. CEL’s spouse is employed by Merck; neither CEL nor his spouse own Merck stock. WB serves on multiple independent...
nt data monitoring committees for Genentech. MB has consulted for Clinique and ToxiMap. MB has received honoraria from the US Environmental Protection Agency, National Institutes of Health, Health Canada, Colorado School of Public Health, Duke University, University of Texas, Data4Justice, Korea University, Organization of Teratology Information Specialists, University of Pennsylvania, Boston University, IOP Publishing, Pacific-10 Conference, UK Research and Innovation, AXA Research Fund, Harvard University, SciQuest and University of Montana. MB has received travel support from the Colorado School of Public Health, University of Texas, Duke University, Boston University, University of Pennsylvania, Harvard University, American Journal of Public Health, Columbia University, CMAS conference and Nature conference. SH has consulted for the Medullary Thyroid Cancer Consortium (Novo Nordisk, AstraZeneca Pharmaceuticals LP, Eli Lilly and Company), Urovant Sciences, Bluebird Bio, Amylyx Pharmaceuticals, Ipsen Bioscience, Covis Pharma GmbH, i2o Therapeutics, Basilea, Balance Ophthalmics, Lykos Therapeutics and Applied Therapeutics. Other authors report no conflicts.
The Journey to a FAIR CORE DATA SET for Diabetes Research in Germany.
The Journey to a FAIR CORE DATA SET for Diabetes Research in Germany.
Fuente:Scientific Data
Extracto:
It
contributes to the reusability of health research studies.
Cita:Sci Data 2024 Oct 21; 11 (1) : 1159.
Autor/es:Inau, Esther Thea (a) Dedié, Angela (b)
institución:(a) Medical Informatics Laboratory, University Medicine Greifswald, Greifswald, Germany. inaue@uni-greifswald.de. (b) German Center for Diabetes Research (DZD), München-Neuherberg, Germany.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Glucose impacts onto the reciprocal reprogramming between mammary adipocytes and cancer cells.
Glucose impacts onto the reciprocal reprogramming between mammary adipocytes and cancer cells.
Fuente:Scientific Reports
Extracto:
Thus, modulating plasticity of peri-tumoral adipocytes may represent a
key point for halting BC progression in metabolically unbalanced patients.
Claves:Adipogenesis, Breast Cancer, Glucose, Mammary Adipocytes, Transcriptional signatures, Tumor Microenvironment
Cita:Sci Rep 2024 Oct 21; 14 (1) : 24674.
Autor/es:Ambrosio, Maria Rosaria (a) Adriaens, Michiel (b)
institución:(a) Institute of Experimental Endocrinology and Oncology "G. Salvatore", National Council of Research (IEOS-CNR), Naples, Italy. mariarosaria.ambrosio@cnr.it. (b) Maastricht Center for Systems Biology (MaCSBio), Maastricht University, Maastricht, The Netherlands.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
institución:(a) Department of Laboratory Medicine, Tongji Shanxi Hospital, Shanxi Bethune Hospital, Shanxi Academy of Medical Sciences, Third Hospital of Shanxi Medical University, Taiyuan, 030032, China. (b) Department of Otolaryngology Head and Neck Surgery, Shanxi Medical University Second Affiliated Hospital, Taiyuan, 030001, China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Model-based meta-analysis of HbA1c reduction across SGLT2 inhibitors using dose adjusted by urinary glucose excretion.
Model-based meta-analysis of HbA1c reduction across SGLT2 inhibitors using dose adjusted by urinary glucose excretion.
Fuente:Scientific Reports
Extracto:
As with SGLT2is, in cases where the efficacy
cannot be easily evaluated but an appropriate pharmacodynamic marker was assessed
in early clinical trials, similar approaches for other drug classes can guide
strategic and evidence-based dose selection in phase III trials.
institución:(a) Laboratory of Clinical Pharmacology and Pharmacometrics, Graduate School of Pharmaceutical Sciences, Chiba University, 1-8-1 Inohana, Chuou-ku, Chiba-shi, Chiba, 260-8679, Japan. hiromi-s@chiba-u.jp. (b) Laboratory of Clinical Pharmacology and Pharmacometrics, Graduate School of Pharmaceutical Sciences, Chiba University, 1-8-1 Inohana, Chuou-ku, Chiba-shi, Chiba, 260-8679, Japan.
Conflicto:Hideki Yoshioka and Akihiro Hisaka work for the Pharmaceuticals and Medical Devices Agency (Tokyo, Japan) at present, but the views expressed in this article are those of the authors and do not necessarily reflect the official views of the Pharmaceuticals and Medical Devices Agency. Yamato Sano is an employee of Pfizer R&D Japan. However, Pfizer R&D Japan is not involved in...
n the analysis of this study. There is no conflict of interest to be disclosed for other authors.
The effect of adding pancreatin to standard otilinium bromide and simethicone treatment in type 2 diabetes mellitus patients with irritable bowel syndrome.
The effect of adding pancreatin to standard otilinium bromide and simethicone treatment in type 2 diabetes mellitus patients with irritable bowel syndrome.
Fuente:Scientific Reports
Extracto:
Further studies are warranted to explore its broader clinical
implications and mechanisms of action.
Autor/es:Karpuzcu, Hulusi Can (a) Turan Erdoğan, Beril (b)
institución:(a) Department of Gastroenterology, Ankara Etlik City Hospital, University of Health Sciences, Varlık Mahallesi, Halil Sezai Erkut Caddesi Yenimahalle, Ankara, Turkey. can.karpuzcu@gmail.com. (b) Department of Endocrinology and Metabolism, Ankara City Hospital, Ankara, Turkey.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Surgical intervention for distal radial fractures with concurrent ulnar styloid fractures may be beneficial for the elderly patients: a retrospective study.
Surgical intervention for distal radial fractures with concurrent ulnar styloid fractures may be beneficial for the elderly patients: a retrospective study.
Fuente:Bmc Musculoskeletal Disorders
Extracto:
Our findings suggest that very old patients with
distal radius fracture accompanied by ulnar styloid fractures may benefit from
ORIF to achieve optimal long-term functional recovery.
Cita:BMC Musculoskelet Disord 2024 Oct 21; 25 (1) : 830.
Autor/es:Lim, Yong Kuan (a) Wu, Wen-Tien (b)
institución:(a) Department of Orthopedics, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Hualien, 970473, Taiwan. (b) Department of Orthopedics, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Hualien, 970473, Taiwan.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
