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Intraoperative radiofrequency ablation for unresectable abdominal paraganglioma
Intraoperative radiofrequency ablation for unresectable abdominal paraganglioma
Fuente:Frontiers in Endocrinology
Tipo de trabajo:Caso clínico
Extracto:
To our
best knowledge, this was the first report on intraoperative RFA that markedly
reduced the size of a large primary unresectable PPGL, along with clinical and
biochemical responses.
Autor/es:Magalhaes, Isabelle P A (a) Boger, Bibiana D (b)
institución:(a) Adrenal Unit, Laboratory of Molecular and Cellular Endocrinology, LIM/25, Division of Endocrinology and Metabolism, Clinics Hospital, University of Sao Paulo Medical School, Sao Paulo, Brazil. (b) Adrenal Unit, Laboratory of Molecular and Cellular Endocrinology, LIM/25, Division of Endocrinology and Metabolism, Clinics Hospital, University of Sao Paulo Medical School, Sao Paulo, Brazil.
Conflicto:The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
Association of high disease activity and serum IL-6 levels with the incidence of inflammatory major organ events in Behçet disease: a prospective registry study.
Association of high disease activity and serum IL-6 levels with the incidence of inflammatory major organ events in Behçet disease: a prospective registry study.
Fuente:Frontiers in Immunology
Extracto:
This study suggests that treatment strategies targeting overall
disease activity and monitoring residual serum IL-6 may help prevent inflammatory
major organ events in BD.
institución:(a) Department of Stem Cell and Immune Regulation, Yokohama City University Graduate School of Medicine, Yokohama, Japan. (b) Department of Stem Cell and Immune Regulation, Yokohama City University Graduate School of Medicine, Yokohama, Japan.
Conflicto:YK has received support from Amgen speaking fees, support for attending meetings and travel, and advisory board, Novartis speaking fees and advisory board, and Nippon Shinyaku grants. Mitsuhiro Takeno has received consulting and speaking fees from Amgen; research grants and speaking fees from AbbVie, Asahi Kasei, Chugai, Eisai, Tanabe-Mitsubishi, and Taisyo; and speaking fees from Astellas, Asympti, Boehringer-Ingelheim, Eli Lily,...
Jansen Pharma, Nippon Shinyaku, Novartis, Ono Pharmaceuticals, Takeda, UBC Japan, and Viatris. Tatsuya Atsumi has received grants from Chugai Pharmaceutical Co., Ltd., Daiichi Sankyo Co. Ltd., Nippon Boehringer Ingelheim Co., Ltd., TEIJIN PHARMA LIMITED., Eisai Co., Ltd., and Eli Lilly Japan K.K. Tetsuya Atsumi has also received consulting fees from Sanofi K.K, GlaxoSmithKline plc, AbbVie Inc., AstraZeneca plc, Chugai Pharmaceutical Co., Ltd., Nippon Boehringer Ingelheim Co., Ltd., Janssen Pharmaceutical K.K., Gilead Sciences, Inc., Eli Lilly Japan K.K., and ONO PHARMACEUTICAL CO., LTD. TA has also received payment or honoraria for lectures, presentations, speakers’ bureaus, manuscript writing, or educational events from Takeda Pharmaceutical Co., Ltd., Astellas Pharma Inc., Mitsubishi Tanabe Pharma Co., Chugai Pharmaceutical Co., Ltd., Daiichi Sankyo Co. Ltd., Pfizer Inc., Alexion Inc., Novartis Pharma K.K., Eli Lilly Japan K.K., Kyowa Kirin Co., Ltd., AbbVie Inc., Nippon Boehringer Ingelheim Co., Ltd., Amgen Inc. UCB Japan Co. Ltd., AstraZeneca plc, and Eisai Co., Ltd. The remaining authors declare that the research was conducted in the absence of any commercial or financial relationships that could be constructed as a potential conflict of interest. The author(s) declared that they were an editorial board member of Frontiers, at the time of submission. This had no impact on the peer review process and the final decision.
Identification of potential biomarkers of gout through weighted gene correlation network analysis.
Identification of potential biomarkers of gout through weighted gene correlation network analysis.
Fuente:Frontiers in Immunology
Extracto:
In this study, we screened and validated essential genes using a
variety of bioinformatics tools to generate novel ideas for the diagnosis and
treatment of gout.
Claves:CXCL1, CXCL2, CXCL8, WGCNA, gout
Cita:Front Immunol 2024; 15 : 1367019.
Autor/es:Wang, Xinyi (a) Yang, Bing (b)
institución:(a) Department of Endocrinology, First Affiliated Hospital, Guangxi Medical University, Nanning, China. (b) Department of Geriatric Endocrinology and Metabolism, First Affiliated Hospital, Guangxi Medical University, Nanning, China.
Conflicto:The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
Antitumor activity of extracellular signal-regulated kinases 1/2 inhibitor BVD-523 (ulixertinib) on thyroid cancer cells.
Antitumor activity of extracellular signal-regulated kinases 1/2 inhibitor BVD-523 (ulixertinib) on thyroid cancer cells.
Fuente:Journal of Cancer Research and Therapeutics
Extracto:
This study reveals
the potent antitumor activity of BVD-523 against thyroid cancer cells bearing
MAPK-activating mutations, offering promise for treating aggressive forms of
thyroid cancer.
Cita:J Cancer Res Ther 2024 Apr 1; 20 (2) : 570-577.
Autor/es:Chen, Yulu (a) Xiao, Xi (b)
institución:(a) Institute of Precision Medicine, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China. (b) Institute of Precision Medicine, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.
Longitudinal changes in body mass index, height, and weight in children with acute myeloid leukemia.
Longitudinal changes in body mass index, height, and weight in children with acute myeloid leukemia.
Fuente:Bmc Pediatrics
Extracto:
Physicians should pay more
attention to the changes in height and weight of children with AML at these
crucial treatment stages and intervene in time.
Claves:Acute myeloid leukemia, Body mass index, Bone age, Children, Height, Weight
Cita:BMC Pediatr 2024 Apr 30; 24 (1) : 293.
Autor/es:Wen, Xiaojia (a) He, Hongbo (b)
institución:(a) Leukemia Department, Hematology Center, Beijing Key Laboratory of Pediatric Hematology Oncology, National Key Clinical Discipline of Pediatric Hematology, National Key Discipline of Pediatrics (Capital Medical University), Key Laboratory of Major Diseases in Children, Ministry of Education, Beijing Children's Hospital, Capital Medical University, National Center for Children's, 56 Nanlishi Road, Beijing, 100045, China. (b) Leukemia Department, Hematology Center, Beijing Key Laboratory of Pediatric Hematology Oncology, National Key Clinical Discipline of Pediatric Hematology, National Key Discipline of Pediatrics (Capital Medical University), Key Laboratory of Major Diseases in Children, Ministry of Education, Beijing Children's Hospital, Capital Medical University, National Center for Children's, 56 Nanlishi Road, Beijing, 100045, China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Unlocking the power of synergy: High-intensity functional training and early time-restricted eating for transformative changes in body composition and cardiometabolic health in inactive women with obesity.
Unlocking the power of synergy: High-intensity functional training and early time-restricted eating for transformative changes in body composition and cardiometabolic health in inactive women with obesity.
Fuente:Plos One
Tipo de trabajo:Estudio clínico
Extracto:
In inactive women with obesity,
combining TRE with HIFT can be a good strategy to induce superior effects on body
composition, lipid profile and glucose regulation compared with either diet or
exercise intervention alone. TRIAL REGISTRATION: Clinical Trials Number:
PACTR202301674821174.
Cita:PLoS One 2024; 19 (5) : e0301369.
Autor/es:Ameur, Ranya (a) Maaloul, Rami (b)
institución:(a) High Institute of Sport and Physical Education of Sfax, University of Sfax, Sfax, Tunisia. (b) Research Laboratory of Evaluation and Management of Musculoskeletal System Pathologies, LR20ES09, University of Sfax, Sfax, Tunisia.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Metabolic Syndrome in people treated with Antipsychotics (RISKMet): A multimethod study protocol investigating genetic, behavioural, and environmental risk factors.
Metabolic Syndrome in people treated with Antipsychotics (RISKMet): A multimethod study protocol investigating genetic, behavioural, and environmental risk factors.
Fuente:Plos One
Extracto:
This project innovates MetS monitoring in psychiatry by using intensive digital
phenotyping, identifying biochemical markers, assessing familial risks, and
including genetically similar healthy controls. STUDY REGISTRATION NUMBER:
ISRCTN18419418 at www.isrctn.com.
Cita:PLoS One 2024; 19 (5) : e0298161.
Autor/es:de Girolamo, Giovanni (a) La Cascia, Caterina (b)
institución:(a) Unit of Epidemiological and Evaluation Psychiatry, IRCCS Istituto Centro San Giovanni di Dio Fatebenefratelli, Brescia, Italy. (b) Department of Biomedicine, Neuroscience, and Advanced Diagnostics, Section of Psychiatry, University of Palermo, Palermo, Italy.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Triglyceride-glucose index as a potential predictor for in-hospital mortality in critically ill patients with intracerebral hemorrhage: a multicenter, case-control study.
Triglyceride-glucose index as a potential predictor for in-hospital mortality in critically ill patients with intracerebral hemorrhage: a multicenter, case-control study.
Fuente:Bmc Geriatrics
Extracto:
This study
established a positive correlation between the TyG index and the risk of
in-hospital and ICU mortality in patients over 60 years who diagnosed with ICH,
suggesting that the TyG index holds promise as an indicator for risk
stratification in this patient population.
Claves:All-cause mortality, Intensive care unit, Intracerebral hemorrhage, Triglyceride-glucose index
Cita:BMC Geriatr 2024 May 1; 24 (1) : 385.
Autor/es:Yang, Yang (a) Liang, Shengru (b)
institución:(a) Department of Emergency, Tangdu Hospital, Fourth Military Medical University, Xi'an, 710038, China. (b) Department of Endocrinology, Tangdu Hospital, Fourth Military Medical University, Xi'an, 710038, China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Development of palliative care clinical practice guidelines and referral care pathways for primary care practitioners in Pakistan.
Development of palliative care clinical practice guidelines and referral care pathways for primary care practitioners in Pakistan.
Fuente:Bmc Palliative Care
Tipo de trabajo:Guía de práctica clínica
Extracto:
The described
clinical practice guidelines and primary care clinical referral pathways will aid
to standardize palliative care provision in Pakistan. These can be used by other
resource constrained settings to develop guidelines within their own local
context.
Claves:Clinical Practice Guideline, Pakistan, Palliative Care, Referral
Cita:BMC Palliat Care 2024 May 1; 23 (1) : 112.
Autor/es:Hashmi, Syeda Amrah (a) Martins, Russell Seth (b)
institución:(a) Center for Clinical Best Practices, Clinical and Translational Research Incubator (CITRIC), Aga Khan University Hospital, Karachi, 74800, Pakistan. (b) Center for Clinical Best Practices, Clinical and Translational Research Incubator (CITRIC), Aga Khan University Hospital, Karachi, 74800, Pakistan.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Association between urinary arsenic species and vitamin D deficiency: a cross-sectional study in Chinese pregnant women.
Association between urinary arsenic species and vitamin D deficiency: a cross-sectional study in Chinese pregnant women.
Fuente:Frontiers in Public Health
Extracto:
According to our
study, there were positive correlations between iAs, especially As(3+), MMA and
VDD, but negative correlations between other As species and VDD. Further studies
are needed to determine the mechanisms that exist between different As species
and VDD.
Claves:BKMR, arsenic species, cross-sectional study, pregnancy, vitamin D deficiency
Cita:Front Public Health 2024; 12 : 1371920.
Autor/es:Zhang, Jingran (a) Bai, Yuxuan (b)
institución:(a) Department of Occupational and Environmental Health, School of Public Health, Tianjin Medical University, Tianjin, China. (b) Key Laboratory of Prevention and Control of Major Diseases in the Population, Ministry of Education, Tianjin Medical University, Tianjin, China.
Conflicto:The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
Serum klotho associated with thyroid hormone in adults: A population-based cross-sectional research.
Serum klotho associated with thyroid hormone in adults: A population-based cross-sectional research.
Fuente:Plos One
Extracto:
There is an L-shaped
nonlinear relationship between ln(klotho) and fT3, tT3, suggesting that klotho
could be involved in the physiological regulation of thyroid function.
Cita:PLoS One 2024; 19 (5) : e0301484.
Autor/es:Zhang, Xia (a) Liu, Xuekui (b)
institución:(a) The Xuzhou Clinical College of Xuzhou Medical University, Xuzhou, Jiangsu, China. (b) Department of Endocrinology, Xuzhou Central Hospital, Xuzhou Institute of Medical Sciences, Xuzhou Clinical School of Nanjing Medical University, Affiliated Hospital of Medical School of Southeast University, Jiangsu, China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Development and evaluation of a usable blastocyst predictive model using the biomechanical properties of human oocytes.
Development and evaluation of a usable blastocyst predictive model using the biomechanical properties of human oocytes.
Fuente:Plos One
Tipo de trabajo:Estudio de cohortes
Extracto:
To date, there is no standard guideline or technique to aid in the
selection of oocytes that have a higher likelihood of developing into usable
blastocysts, which are chosen for transfer or vitrification. This study provides
a comprehensive workflow of extracting biomechanical properties and building a
predictive classifier using these properties to predict mature oocytes'
developmental potential. The classifier has greater accuracy in predicting the
formation of usable blastocysts than the predictions provided by morphological
information or maternal factors. The measurement procedure did not negatively
affect embryo culture outcomes. While further analysis is necessary, this study
shows the potential of using biomechanical properties of oocytes to predict
embryo developmental outcomes.
Cita:PLoS One 2024; 19 (5) : e0299602.
Autor/es:Meyer, Daniel (a) Kort, Jonathan (b)
institución:(a) Department of Bioengineering, Stanford University, Stanford, CA, United States of America. (b) Division of Reproductive Endocrinology and Infertility, Stanford University, Stanford, CA, United States of America.
Conflicto:I have read the journal’s policy and the authors of this manuscript have the following competing interests: Barry Behr currently serves as the chief technology officer at Inti Labs. Jack Yu Jen Huang served as an advisor of Inti Labs. Daniel Meyer is a consultant for Inti Labs. This does not alter our adherence to PLOS ONE policies on sharing...
ng data and materials.
Association between low-density lipoprotein cholesterol levels and serum uric acid to serum creatinine ratio in Chinese male gout patients.
Association between low-density lipoprotein cholesterol levels and serum uric acid to serum creatinine ratio in Chinese male gout patients.
Fuente:Scientific Reports
Extracto:
Our findings suggest that LDL-C levels may be
more noteworthy in overweight and/or obese male gout patients.
Cita:Sci Rep 2024 May 2; 14 (1) : 10121.
Autor/es:Shao, Qian (a) Chi, Jingwei (b)
institución:(a) Department of Endocrinology and Metabolism, the Affiliated Hospital of Medical College Qingdao University, Qingdao, China. (b) Department of Endocrinology, the Affiliated Hospital of Jining Medical University, Jining Medical University, Jining, China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Efficacy of sucrose and povidone-iodine mixtures in peritoneal dialysis catheter exit-site care.
Efficacy of sucrose and povidone-iodine mixtures in peritoneal dialysis catheter exit-site care.
Fuente:Bmc Nephrology
Extracto:
Our
results showed that the use of SPI may be a promising option for preventing the
incidence of ESI in patients with PD. TRIAL REGISTRATION: This study was approved
by the Keio University School of Medicine Ethics Committee (approval number
20231078) on August 28, 2023. Retrospectively registered.
institución:(a) Division of Endocrinology, Metabolism and Nephrology, Department of Internal Medicine, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-Ku, Tokyo, 160-8582, Japan. (b) Apheresis and Dialysis Center, Keio University School of Medicine, Tokyo, Japan.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Effect of postpartum depression and role of infant feeding practices on relative weight of child at 1 and 3 years of age.
Effect of postpartum depression and role of infant feeding practices on relative weight of child at 1 and 3 years of age.
Fuente:Bmc Pregnancy and Childbirth
Extracto:
The significant association between PPD at 6 months
and child's BMI z-score at 3 years of age, in conjunction with birth trends and
high prevalence of PPD, can add to the body of evidence that there is need for
multiple assessment across the first postpartum year to rule out PPD as early
screening and early interventions may benefit both maternal health and child
development outcomes. These findings can indicate the need for establishing
support systems for care-giving activities for mothers with PPD.
Cita:BMC Pregnancy Childbirth 2024 May 2; 24 (1) : 336.
Autor/es:Shrestha, Drishti (a) K C Bhandari, Aliza (b)
institución:(a) Graduate School of Public Health, St. Luke's International University, Tokyo, Japan. 21MP217@slcn.ac.jp. (b) Graduate School of Public Health, St. Luke's International University, Tokyo, Japan.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Pituitary abscess: a descriptive analysis of a series of 19 patients-a multi-center experience.
Pituitary abscess: a descriptive analysis of a series of 19 patients-a multi-center experience.
Fuente:European Journal of Medical Research
Extracto:
Given the lack of clarity in
preoperative diagnosis, typical intraoperative findings and effective antibiotics
treatment are more indicative of the correct diagnosis than other tests. In terms
of therapy, optimal surgical intervention and active postoperative antibiotic
treatment contribute to resolving the challenges posed by PA.
institución:(a) Departments of Neurosurgery, The Third Affiliated Hospital, Naval Medical University, Shanghai, 200438, China. (b) Department of Radiotherapy & Oncology, The No. 2 People's Hospital of Wuhu City, Wuhu, Anhui, China.
Burden of COVID-19 pandemic on tuberculosis hospitalisation patterns at a tertiary care hospital in Rajasthan, India: a retrospective analysis.
Burden of COVID-19 pandemic on tuberculosis hospitalisation patterns at a tertiary care hospital in Rajasthan, India: a retrospective analysis.
Fuente:Bmj Open
Extracto:
The study underscores the influence of the
COVID-19 pandemic on the TB landscape and hospitalisation dynamics. Notably,
patient burden of TB declined during the COVID-19 era, with a decline in the
post-COVID-19 era compared with the pre-COVID-19 era. Prolonged hospitalisation
in the post-COVID-19 period indicates the need for adaptive healthcare strategies
and the formulation of public health policies in a post-pandemic context. These
findings contribute to a comprehensive understanding of the evolving TB scenario,
emphasising the necessity for tailored healthcare approaches in the aftermath of
a global health crisis.
Claves:COVID-19, Public health, Tuberculosis
Cita:BMJ Open 2024 May 3; 14 (5) : e080623.
Autor/es:Rajotiya, Sumit (a) Mishra, Shivang (b)
institución:(a) Department of Pharmacy Practice, NIMS University, Jaipur, Rajasthan, India. (b) Department of Pharmacy Practice, NIMS University, Jaipur, Rajasthan, India.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Interaction of obesity and proteins associated with the NLRP3 inflammasome following mild traumatic brain injury.
Interaction of obesity and proteins associated with the NLRP3 inflammasome following mild traumatic brain injury.
Fuente:Scientific Reports
Extracto:
In this
single center mTBI cohort, obese BMI interacted with higher acute concentrations
of NLRP3 inflammasome proteins and worsened short- and long-term clinical
outcomes.
Cita:Sci Rep 2024 May 3; 14 (1) : 10178.
Autor/es:Eagle, Shawn R (a) Basantani, Mahesh K (b)
institución:(a) Department of Neurological Surgery, University of Pittsburgh, 3550 Terrace St, Pittsburgh, PA, 15261, USA. eaglesr2@upmc.edu. (b) Division of Endocrinology and Metabolism, Department of Medicine, University of Pittsburgh, Pittsburgh, PA, USA.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
The association of depressive symptoms with handgrip strength and gait speed in community-dwelling older adults: data from the baseline phase of Birjand Longitudinal Aging Study.
The association of depressive symptoms with handgrip strength and gait speed in community-dwelling older adults: data from the baseline phase of Birjand Longitudinal Aging Study.
Fuente:Bmc Geriatrics
Extracto:
Our findings suggest that older people
residing in Birjand, Iran with a moderate HGS are less likely to suffer from
depressive symptoms than those with lower HGS.
Claves:Depression, Gait speed, Handgrip strength, Older adults, Physical function
Cita:BMC Geriatr 2024 May 3; 24 (1) : 393.
Autor/es:Nazari, Tina (a) Moodi, Mitra (b)
institución:(a) Department of Medical Geriatrics, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran. (b) Social Determinants of Health Research Center, Birjand University of Medical Sciences, Birjand, Iran.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Association of osteoporotic fractures of femoral neck and femoral neck geometric parameters in native Chinese women.
Association of osteoporotic fractures of femoral neck and femoral neck geometric parameters in native Chinese women.
Fuente:Bmc Musculoskeletal Disorders
Extracto:
These results suggest that the majority of
osteoporotic fractures of the femoral neck of native Chinese women occur in
patients with osteoporosis. CT thinning or BR increase of FNGPs may be
independent predictors of fragility fracture of femoral neck in native Chinese
women unrelated to BMD.
Cita:BMC Musculoskelet Disord 2024 May 3; 25 (1) : 349.
Autor/es:Li, Lin (a) Shen, Yi (b)
institución:(a) National Clinical Research Center for Metabolic Diseases, Hunan Provincial Key Laboratory of Metabolic Bone Diseases, Department of Metabolism and Endocrinology, The Second Xiangya, Hospital of Central South University, Changsha, 410011, China. (b) Department of Endocrinology and Metabolism, The Affiliated Changsha Hospital of Xiangya School of Medicine, Central South University, Changsha, China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación