Imbalance of gut microbiota in gestational diabetes.

Imbalance of gut microbiota in gestational diabetes.

Fuente:Bmc Pregnancy and Childbirth

Tipo de trabajo:Estudio clínico

Extracto: Abnormal increases and decreases in the abundances of gut microbiota components, especially Faecalibacterium prausnitzii, were observed in GD patients. TRIAL REGISTRATION: The cross-sectional research was conducted in accordance with the Declaration of Helsinki, and approved by Sir Run Run Shaw Hospital Clinical Trials and Biomedical Ethics Committee. The study has been registered in the Chinese Clinical Trial Registry (ChiCTR1900026164, 24/09/2019, http://www.chictr.org.cn/showproj.aspx?proj=43,455 ).

Claves:Consequences of- damage, Faecalibacterium prausnitzii, Gestational diabetes, Gut microbiota, Protective compensation

Cita:BMC Pregnancy Childbirth 2024 Apr 1; 24 (1) : 226.

Autor/es:Shen, Weiyi (a)
Chen, Qianyi (b)

institución:(a) Department of Pathology, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, 310016, Zhejiang Province, China.
(b) Department of Gastroenterology, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, 310016, Zhejiang Province, China.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1186/s12884-024-06423-0

Rare copy number variation in autoimmune Addison's disease.

Rare copy number variation in autoimmune Addison's disease.

Fuente:Frontiers in Immunology

Extracto: In conclusion, rare CNVs do not appear to be a major cause of AAD but further studies are needed to ascertain the potential contribution of rare deletions to the polygenic load of AAD susceptibility.

Claves:Addison’s disease, BCL2L11, LRBA, autoimmune, copy number variation, rare deletions

Cita:Front Immunol 2024; 15 : 1374499.

Autor/es:Artaza, Haydee (a)
Eriksson, Daniel (b)

institución:(a) Department of Clinical Science, University of Bergen, Bergen, Norway.
(b) K. G. Jebsen Center for Autoimmune Diseases, University of Bergen, Bergen, Norway.

Conflicto:The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. The author(s) declared that they were an editorial board member of Frontiers, at the time of submission. This had no impact on the peer review process and the final decision.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3389/fimmu.2024.1374499

A machine learning approach to predicting vascular calcification risk of type 2 diabetes: A retrospective study.

A machine learning approach to predicting vascular calcification risk of type 2 diabetes: A retrospective study.

Fuente:Clinical Cardiology

Extracto: This study developed a predictive model of VC based on ML and clinical features in type 2 diabetic patients. The NB model is a tool with potential to facilitate clinicians in identifying VC in high-risk patients.

Claves:Naive Bayes, cross sectional study, k‐nearest neighbor, machine learning, prediction model, type 2 diabetes mellitus, vascular calcification

Cita:Clin Cardiol 2024 Apr; 47 (4) : e24264.

Autor/es:Liang, Xue (a)
Li, Xinyu (b)

institución:(a) Department of Endocrinology, Dalian Municipal Central Hospital, Dalian, China.
(b) Graduate School, Dalian Medical University, Dalian, China.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe impreso

Idioma:Inglés

País de fuente:EE.UU.

Sitio web:http://dx.doi.org/10.1002/clc.24264

The Impact of Optimal Glycemic Control on Tuberculosis Treatment Outcomes in Patients With Diabetes Mellitus

The Impact of Optimal Glycemic Control on Tuberculosis Treatment Outcomes in Patients With Diabetes Mellitus

Fuente:Jmir Public Health and Surveillance

Tipo de trabajo:Revisión sistemática

Extracto: We concluded that optimal glycemic control is crucial for reducing susceptibility, minimizing complications, and improving treatment outcomes in patients with TB with DM. Emphasizing effective health management and health care strategies are essential in achieving this control. Integrating comprehensive care among patients with TB with DM will enhance patient outcomes and alleviate the burden of disease in this population. TRIAL REGISTRATION: PROSPERO CRD42023427362; https://www.crd.york.ac.uk/prospero/display_record.php?RecordID=427362.

Claves:DM, TB, burden, diabetes, diabetes mellitus, disease burden, glycemic control, health care, health management, healthcare, meta-analysis, mortality, optical glycemic control, patients, poor glycemic control, risks, systematic review, treatment, treatment outcome, tuberculosis, tuberculosis treatment

Cita:JMIR Public Health Surveill 2024 Apr 2; 10 : e53948.

Autor/es:Zhao, Li (a)
Gao, Feng (b)

institución:(a) Department of Tuberculosis III, Wuhan Pulmonary Hospital, Wuhan, China.
(b) Department of Endocrinology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Canadá

Sitio web:http://dx.doi.org/10.2196/53948

Bispecific aptamer-decorated and light-triggered nanoparticles targeting tumor and stromal cells in breast cancer derived organoids: implications for precision phototherapies.

Fuente:Journal of Experimental & Clinical Cancer Research Cr

Extracto: Our study proposes smart, novel and safe multifunctional nanoplatforms simultaneously addressing cancer-stroma within the tumor microenvironment, which are: (i) actively delivered to the targeted cells through highly specific aptamers; (ii) localized by means of their luminescence, and (iii) activated via minimally invasive light, launching efficient tumor death, thus providing innovative precision therapeutics. Given the unique features, the proposed dual targeted nanoformulations may open a new door to precision cancer treatment.

Claves:Aptamer, Dual targeting, EGFR, Nanomedicine, PDGFRβ, Patient-derived cancer organoids, Phototherapy, Tumor microenvironment

Cita:J Exp Clin Cancer Res 2024 Mar 26; 43 (1) : 92.

Autor/es:Camorani, Simona (a)
Caliendo, Alessandra (b)

institución:(a) Institute of Experimental Endocrinology and Oncology "Gaetano Salvatore", National Research Council, 80131, Naples, Italy.
(b) Institute of Experimental Endocrinology and Oncology "Gaetano Salvatore", National Research Council, 80131, Naples, Italy.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1186/s13046-024-03014-x

A systematic review of progranulin concentrations in biofluids in over 7,000 people-assessing the pathogenicity of GRN mutations and other influencing factors.

Fuente:Alzheimer's Research & Therapy

Tipo de trabajo:Revisión

Extracto: These results further support the usefulness of PGRN concentration for the identification of the large majority of pathogenic mutations in the GRN gene. Furthermore, these results highlight the importance of considering additional factors, such as mutation type, sex and age when interpreting PGRN concentrations. This will be particularly important as we enter the era of trials for progranulin-associated FTD.

Claves:Frontotemporal dementia, Progranulin

Cita:Alzheimers Res Ther 2024 Mar 28; 16 (1) : 66.

Autor/es:Swift, Imogen J (a)
Rademakers, Rosa (b)

institución:(a) Department of Neurodegenerative Disease, Dementia Research Institute, UCL Institute of Neurology, Queen Square, London, UK.
(b) Department of Neurodegenerative Disease, Dementia Research Centre, UCL Institute of Neurology, Queen Square, London, WC1N 3BG, UK.

Conflicto:HZ has served at scientific advisory boards and/or as a consultant for Abbvie, Acumen, Alector, Alzinova, ALZPath, Annexon, Apellis, Artery Therapeutics, AZTherapies, Cognito Therapeutics, CogRx, Denali, Eisai, Nervgen, Novo Nordisk, Optoceutics, Passage Bio, Pinteon Therapeutics, Prothena, Red Abbey Labs, reMYND, Roche, Samumed, Siemens Healthineers, Triplet Therapeutics, and Wave, has given lectures in symposia sponsored by Alzecure, Biogen, Cellectricon, Fujirebio, Lilly,... and Roche, and is a co-founder of Brain Biomarker Solutions in Gothenburg AB (BBS), which is a part of the GU Ventures Incubator Program (outside submitted work). JDR has served on medical advisory boards and consultancy for Alector, Arkuda Therapeutics, Wave Life Sciences, and Prevail Therapeutics. Consultancy for UCB, AC Immune, Astex Pharmaceuticals, Biogen, Takeda and Eisai. SKS has received author’s and advisory honoraria from Takeda/Shire and Medice Arzneimittel Pütter GmbH in the last 3 years. AL participated in advisory boards from Biogen, Eisai, Fujirebio-Europe, Grifols, Novartis, Roche, Otsuka Pharmaceutical, Nutricia, Zambón, y NovoNordisk. AL declares a filed patent application (WO2019175379 A1 Markers of synaptopathy in neurodegenerative disease). DA participated in advisory boards from Fujirebio-Europe, Roche Diagnostics, Grifols S.A. and Lilly, and received speaker honoraria from Fujirebio-Europe, Roche Diagnostics, Nutricia, Krka Farmacéutica S.L., Zambon S.A.U. and Esteve Pharmaceuticals S.A. DA declares a filed patent application (WO2019175379 A1 Markers of synaptopathy in neurodegenerative disease). MS has received consultancy honoraria from Ionis, UCB, Prevail, Orphazyme, Servier, Reata, GenOrph, AviadoBio, Biohaven, Zevra,and Lilly, all unrelated to the present manuscript. IIG participated in advisory boards from UCB Pharma S.A., and received speaker honoraria from Nutricia, Kern Pharma S., Krka Farmacéutica S.L., Zambon S.A.U. and Esteve Pharmaceuticals S.A.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1186/s13195-024-01420-z

Effects of Switching from Degludec to Glargine U300 in Patients with Insulin-Dependent Type 1 Diabetes: A Retrospective Study.

Fuente:Medicina (kaunas, Lithuania)

Extracto: Conclusions: Switching from Deg to Gla-300 improved the SD-FBG and decreased the frequency of nocturnal hypoglycemia in insulin-dependent type 1 diabetes treated with Deg-containing BBT, especially in cases with low serum albumin levels and a high GV.

Claves:degludec, glargine U300, glycemic variability, hypoglycemia, type 1 diabetes

Cita:Medicina (Kaunas) 2024 Mar 8; 60 (3)

Autor/es:Sawamura, Toshitaka (a)
Karashima, Shigehiro (b)

institución:(a) Department of Internal Medicine, Asanogawa General Hospital, 83 Kosakamachi, Kanazawa 910-8621, Japan.
(b) Department of Endocrinology and Metabolism, Kanazawa University Graduate School of Medicine, 13-1 Takaramachi, Kanazawa 920-8641, Japan.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3390/medicina60030450

The Role of Continuous Glucose Monitoring in Detecting Early Dysglycemia and Clinical Outcomes in Patients with Cystic Fibrosis.

Fuente:Medicina (kaunas, Lithuania)

Extracto: The aim of this review is to provide an update on the pathophysiological mechanisms of CFRD, recent advances in the use of CGM for CFRD screening, and the association between CGM measures and CF-related clinical outcomes.

Claves:clinical outcomes, continuous glucose monitoring, cystic fibrosis-related diabetes, screening

Cita:Medicina (Kaunas) 2024 Mar 14; 60 (3)

Autor/es:Kirigin Biloš, Lora Stanka (a)
Altabas, Velimir (b)

institución:(a) Department of Endocrinology, Diabetes and Metabolic Diseases "Mladen Sekso", University Hospital Centre "Sestre Milosrdnice", 10000 Zagreb, Croatia.
(b) Department of Endocrinology, Diabetes and Metabolic Diseases "Mladen Sekso", University Hospital Centre "Sestre Milosrdnice", 10000 Zagreb, Croatia.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3390/medicina60030477

Primary Thyroid Lymphoma: A Retrospective-Observational Study in a Single Institutional Center.

Fuente:Medicina (kaunas, Lithuania)

Extracto: PTL is a lymphoid neoplasia with favorable outcome, with relatively long survival if it is diagnosed at younger ages.

Claves:Hashimoto thyroiditis, fine needle aspirate, non-Hodgkin B-cell lymphomas, primary thyroid lymphoma, survival

Cita:Medicina (Kaunas) 2024 Mar 14; 60 (3)

Autor/es:Vita, Octavia (a)
Dema, Alis (b)

institución:(a) Department of Microscopic Morphology-Morphopatology, ANAPATMOL Research Center, "Victor Babes" University of Medicine and Pharmacy, 300041 Timisoara, Romania.
(b) Department of Microscopic Morphology-Morphopatology, ANAPATMOL Research Center, "Victor Babes" University of Medicine and Pharmacy, 300041 Timisoara, Romania.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3390/medicina60030476

Does Basal Morning Luteinizing Hormone (bLH) Predict Central Precocious Puberty (CPP) in Girls?

Fuente:Medicina (kaunas, Lithuania)

Extracto: The GnRH test, even reduced to 30 min, could be reserved for girls who show low intermediate morning bLH and specific clinical signs of pubertal development.

Claves:GnRH test, basal luteinizing hormone (bLH), central precocious puberty

Cita:Medicina (Kaunas) 2024 Mar 18; 60 (3)

Autor/es:Baronio, Federico (a)
Assirelli, Valentina (b)

institución:(a) Pediatric Unit, IRCCS Azienda Ospedaliero-Universitaria di Bologna, 40138 Bologna, Italy.
(b) Pediatric Unit, IRCCS Azienda Ospedaliero-Universitaria di Bologna, 40138 Bologna, Italy.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3390/medicina60030497

Athlete biological passport: longitudinal biomarkers and statistics in the fight against doping.

Fuente:Arhiv Za Higijenu Rada I Toksikologiju

Extracto: The ABP has already changed the fight against doping, but its importance will further grow with the new modules (e.g., endocrinological), parameters (e.g., plasma volume-independent parameters), and complementing indirect methods (e.g., transcriptomic).

Claves:ABP, biochemical factors, biokemijski čimbenici, biološka putovnica sportaša, confounding factors, haematological module, hematološki modul, steroidal module, steroidni modul, zbunjujući čimbenici

Cita:Arh Hig Rada Toksikol 2024 Mar 1; 75 (1) : 24-31.

Autor/es:Dragčević, Dora (a)
Pandžić Jakšić, Vlatka (b)

institución:(a) University Hospital Merkur, Department of Haematology, Zagreb, Croatia.
(b) University Hospital Dubrava, Department of Endocrinology, Zagreb, Croatia.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Croacia

Sitio web:http://dx.doi.org/10.2478/aiht-2024-75-3793

The association of hypophysitis with immune checkpoint inhibitors use: Gaining insight through the FDA pharmacovigilance database.

Fuente:Medicine

Extracto: Nivolumab, pembrolizumab, ipilimumab, and atezolizumab have all been associated with hypophysitis, which can negatively impact quality of life, and early recognition and management of immune checkpoint inhibitor-related hypophysitis is critical.

Cita:Medicine (Baltimore) 2024 Mar 29; 103 (13) : e37587.

Autor/es:Tang, Qirui (a)
Han, Yaru (b)

institución:(a) Clinical School of Medicine, Jining Medical University, Jining, China.
(b) Department of Endocrinology, Jining City Hospital of Traditional Chinese Medicine, Jining, China.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe impreso

Idioma:Inglés

País de fuente:EE.UU.

Sitio web:http://dx.doi.org/10.1097/MD.0000000000037587

Effects of hysteroscopic septum incision versus expectant management on IVF outcomes in women with complete septate uterus: a retrospective study.

Fuente:Bmc Women's Health

Extracto: Hysteroscopic septum incision does not appear to yield improved IVF outcomes compared to expectant management in infertile women with a complete septate uterus and no history of recurrent pregnancy loss.

Claves:In vitro Fertilization, Septate uterus, Septum incision

Cita:BMC Womens Health 2024 Mar 30; 24 (1) : 202.

Autor/es:Zhang, Jiajia (a)
Kang, Jia (b)

institución:(a) Center for Reproductive Medicine, Department of Obstetrics and Gynecology, Peking University Third Hospital, Beijing, 100191, China.
(b) National Clinical Research Center for Obstetrics and Gynecology, Peking University Third Hospital, Beijing, China.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1186/s12905-024-03022-1

The relationship between the tumor and its innervation

Fuente:Endocrine Regulations

Tipo de trabajo:Revisión

Extracto: The aim of the present review was to 1) summarize the available knowledge regarding the course of tumor innervation, 2) present the potential mechanisms and pathways for the possible induction of new nerve fibers into the tumor microenvironment, and 3) highlight the functional significance/consequences of the nerves infiltrating the tumors.

Claves:axonogenesis, innervation, neurogenesis, tumor

Cita:Endocr Regul 2024 Jan 1; 58 (1) : 68-82.

Autor/es:Blasko, Filip (a)
Horvathova, Lubica (b)

institución:(a) Institute of Experimental Endocrinology, Biomedical Research Center, Slovak Academy of Sciences, Bratislava, Slovakia.
(b) Institute of Physiology, Faculty of Medicine, Comenius University Bratislava, Bratislava, Slovakia.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Alemania

Sitio web:http://dx.doi.org/10.2478/enr-2024-0008

Distinguishing benign and malignant thyroid nodules using plasma trimethylamine N-oxide, carnitine, choline and betaine.

Distinguishing benign and malignant thyroid nodules using plasma trimethylamine N-oxide, carnitine, choline and betaine.

Fuente:Journal of Cancer Research and Clinical Oncology

Extracto: Plasma TMAO, along with its precursors could serve as new biomarkers for the diagnosis of benign and malignant thyroid nodules.

Claves:Betaine, Biomarker, Carnitine, Choline, Thyroid cancer, Trimethylamine N-oxide (TMAO)

Cita:J Cancer Res Clin Oncol 2024 Mar 20; 150 (3) : 142.

Autor/es:Shi, Liang (a)
Guo, Muhong (b)

institución:(a) Department of Nuclear Medicine, Nanjing First Hospital, Nanjing Medical University, Nanjing, 210006, China.
(b) Department of General Surgery, Nanjing First Hospital, Nanjing Medical University, Nanjing, 210006, China.

Conflicto:The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Alemania

Sitio web:http://dx.doi.org/10.1007/s00432-024-05666-w

Experiences of the clinical academic pathway: a qualitative study in Greater Manchester to improve the opportunities of minoritised clinical academics.

Experiences of the clinical academic pathway: a qualitative study in Greater Manchester to improve the opportunities of minoritised clinical academics.

Fuente:Bmj Open

Extracto: Cultural and structural interventions are needed, such as introducing financial support for early career CAs and intercalating healthcare students to promote wider social and cultural change and increase the feelings of belonging and representation across the entire CA pipeline.

Claves:MEDICAL EDUCATION & TRAINING, QUALITATIVE RESEARCH, Sexual and Gender Minorities

Cita:BMJ Open 2024 Mar 19; 14 (3) : e079759.

Autor/es:Lin, Chiu-Yi (a)
Greco, Cinzia (b)

institución:(a) Division of Pharmacy and Optometry, School of Health Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester, UK.
(b) Centre for the History of Science, Technology and Medicine, The University of Manchester, Manchester, UK.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1136/bmjopen-2023-079759

Finerenone cardiovascular and kidney outcomes by age and sex

Fuente:Bmj Open

Tipo de trabajo:Estudio multicéntrico

Extracto: Finerenone improved cardiovascular and kidney composite outcomes with no significant heterogeneity between age and sex subgroups; however, the effect on HHF appeared more pronounced in males. Finerenone demonstrated a similar safety profile across age and sex subgroups. TRIAL REGISTRATION NUMBERS: NCT02540993, NCT02545049.

Claves:cardiovascular disease, diabetes & endocrinology, diabetic nephropathy & vascular disease, risk factors

Cita:BMJ Open 2024 Mar 19; 14 (3) : e076444.

Autor/es:Bansal, Shweta (a)
Canziani, Maria E F (b)

institución:(a) Division of Nephrology, Department of Medicine, University of Texas Health San Antonio, San Antonio, Texas, USA bansals3@uthscsa.edu.
(b) Nephrology Division, Federal University of São Paulo, São Paulo, Brazil.

Conflicto:Competing interests: SB reports research support from 3ive, Bayer, Boehringer Ingelheim, Novartis and Novo Nordisk; honorarium from UpToDate; consultancy fees from Baxter; and speaker bureau fees from Home Dialysis University and PD Excellence Academy. MEFC reports consultancy fees from AstraZeneca, Bayer, Boehringer Ingelheim, and Fresenius Medical Care, and research support from Baxter and Fresenius. RB reports consultancy fees from AstraZeneca,... Bayer, Boehringer Ingelheim, Gilead, MSD, Mundipharma, Sanofi and Servier. SDA reports grants from Abbott Vascular and Vifor International; and personal fees from Amgen, AstraZeneca, Bayer, Boehringer Ingelheim, BioVentrix, Brahms, Cardiac Dimensions, Cardior, Cordio, CVRx, Edwards, Impulse Dynamics, Janssen, Novartis, Occlutech, Respicardia, Servier, Vectorious and V-Wave. GLB reports consultancy fees from Alnylam, Ionis and Merck. GF is a trial committee member for Amgen, Bayer (no fees received), Boehringer Ingelheim, Medtronic, Novartis, Servier and Vifor. PR reports personal fees from Bayer during the conduct of the study; he has received research support and personal fees from AstraZeneca and Novo Nordisk, and personal fees from Astellas, Boehringer Ingelheim, Eli Lilly, Gilead, Mundipharma, Sanofi and Vifor; all fees are given to Steno Diabetes Center Copenhagen. LMR reports consultancy fees from Bayer. AEF, PK, AL and MB are all full-time employees of Bayer. BP reports consultant fees for AstraZeneca, Bayer, Boehringer Ingelheim, Brainstorm Medical, Cereno Scientific, G3 Pharmaceuticals, KBP Biosciences, PhaseBio, Proton Intel, Sanofi/Lexicon, Sarfez, scPharmaceuticals, SQ Innovation, Tricida, and Vifor/Relypsa; he has stock options for Brainstorm Medical, Cereno Scientific, G3 Pharmaceuticals, KBP Biosciences, Proton Intel, Sarfez, scPharmaceuticals, SQ Innovation, Tricida, and Vifor/Relypsa; he also holds a patent for site-specific delivery of eplerenone to the myocardium (US patent #9931412) and a provisional patent for histone-acetylation-modulating agents for the treatment and prevention of organ injury (provisional patent US 63/045784).

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1136/bmjopen-2023-076444

Relationship between social isolation and glycaemic control of people previously diagnosed with diabetes: secondary analysis from the CHARLS.

Fuente:Bmj Open

Extracto: Middle-aged men with diabetes with higher social isolation tend to have higher blood glucose and glycosylated haemoglobin levels. This subset of patients requires targeted attention to provide social support from family and friends for improved glycaemic control. If necessary, education on diabetes should be made available to family members and friends.

Claves:Diabetes & endocrinology, Lipid disorders, Social Interaction

Cita:BMJ Open 2024 Mar 19; 14 (3) : e076106.

Autor/es:Lu, Qiuping (a)
Qu, Liyuan (b)

institución:(a) Department of Endocrinology, The Sixth Affiliated Hospital ，School of Medicine， South China University of Technology, Foshan City, Guangdong, China.
(b) Department of Endocrinology and Metabolism, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong, China.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1136/bmjopen-2023-076106

Can glycated haemoglobin (HbA1c) be used as a predictor of left ventricular diastolic dysfunction in non-hypertensive patients with newly diagnosed type 2 diabetes mellitus: a cross-sectional study at a tertiary care centre in Eastern India.

Fuente:Bmj Open

Extracto: This study demonstrated that age and HbA1c levels are independent predictors of LVDD in patients with newly diagnosed type 2 DM without hypertension. A cut-off value of 9.5% for HbA1c was identified with a high specificity and PPV for predicting LVDD in patients with newly diagnosed type 2 diabetes. This underscores the importance of conducting echocardiography in patients with newly diagnosed asymptomatic type 2 diabetes with HbA1c 9.5% or more to assess LVDD, allowing for prompt interventions if necessary and to decelerate the progression towards heart failure.

Claves:DIABETES & ENDOCRINOLOGY, Echocardiography, Heart failure

Cita:BMJ Open 2024 Mar 19; 14 (3) : e081269.

Autor/es:Porel, Rajdeep (a)
Shyama, Shyama (b)

institución:(a) Department of General Medicine, All India Institute of Medical Sciences, Patna, Bihar, India.
(b) Department of General Medicine, All India Institute of Medical Sciences, Patna, Bihar, India drshyamathesisrajdeep@gmail.com.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1136/bmjopen-2023-081269

Decentralising chronic disease management in sub-Saharan Africa: a protocol for the qualitative process evaluation of community-based integrated management of HIV, diabetes and hypertension in Tanzania and Uganda.

Fuente:Bmj Open

Tipo de trabajo:Estudio aleatorizado

Extracto: TRIAL REGISTRATION NUMBER: ISRCTN15319595.

Claves:DIABETES & ENDOCRINOLOGY, HIV & AIDS, Hypertension

Cita:BMJ Open 2024 Mar 20; 14 (3) : e078044.

Autor/es:Van Hout, Marie-Claire (a)
Akugizibwe, Mathias (b)

institución:(a) Public Health Institute, Liverpool John Moores University, Liverpool, UK M.C.VanHout@ljmu.ac.uk.
(b) MRC/UVRI and LSHTM Uganda Research Unit, Entebbe, Wakiso, Uganda.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1136/bmjopen-2023-078044