Case report: Long term response to growth hormone in a child with Silver-Russell syndrome-like phenotype due to a novel paternally inherited IGF2 variant.

Case report: Long term response to growth hormone in a child with Silver-Russell syndrome-like phenotype due to a novel paternally inherited IGF2 variant.

Fuente:Frontiers in Endocrinology

Extracto: In addition, we report that long-term growth hormone treatment improves height SDS in this patient.

Claves:GH therapy, IGF2 variant, Silver-Russel syndrome, children, growth retardation

Cita:Front Endocrinol (Lausanne) 2024; 15 : 1364234.

Autor/es:Ventresca, Silvia (a)
Lepri, Francesca Romana (b)

institución:(a) Pediatric Section, University Hospital Arcispedale Sant'Anna, University of Ferrara, Ferrara, Italy.
(b) Endocrinology and Diabetology Unit, Pediatric University Department, Bambino Gesù Children's Hospital, Rome, Italy.

Conflicto:The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. The author(s) declared that they were an editorial board member of Frontiers, at the time of submission. This had no impact on the peer review process and the final decision.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3389/fendo.2024.1364234

Practice effects of personalized interventions with interdisciplinary teamwork in type 2 diabetes remission: a retrospective study.

Fuente:Frontiers in Endocrinology

Tipo de trabajo:Orientaciones y guía

Extracto: Through an interdisciplinary team intervention strategy, we significantly optimized the glucose metabolism, lipid metabolism, and BMI status of patients with T2DM, making diabetes remission an achievable goal, which provides valuable experience for further optimization of diabetes prevention and control protocols.

Claves:diabetes remission, interdisciplinary, personalized interventions, retrospective study, type 2 diabetes

Cita:Front Endocrinol (Lausanne) 2024; 15 : 1341531.

Autor/es:Tian, Xiaona (a)
Tang, Yujin (b)

institución:(a) Eighth Clinical School, Guangzhou University of Chinese Medicine, Foshan, Guangdong, China.
(b) Eighth Clinical School, Guangzhou University of Chinese Medicine, Foshan, Guangdong, China.

Conflicto:Author JW was employed by Guangzhou ShanMao Health Technology LTD. The remaining authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3389/fendo.2024.1341531

Association of metabolic syndrome and sarcopenia with all-cause and cardiovascular mortality

Fuente:Frontiers in Endocrinology

Tipo de trabajo:Estudio de cohortes

Extracto: The coexistence of MetS and SP increased the risk of all-cause and cardiovascular mortality, particularly in males and in nonelderly populations. Individuals with either MetS or SP may require more careful management to prevent the development of other diseases and thereby reduce mortality.

Claves:NHANES, all-cause mortality, cardiovascular mortality, metabolic syndrome, sarcopenia

Cita:Front Endocrinol (Lausanne) 2024; 15 : 1346669.

Autor/es:Huang, Weihong (a)
Deng, Siyi (b)

institución:(a) Department of Endocrinology and Metabolism, Shunde Hospital, Southern Medical University (The First People's Hospital of Shunde), Foshan, Guangdong, China.
(b) Department of Cardiology, The First Affiliated Hospital of Shantou University Medical College, Shantou, Guangdong, China.

Conflicto:The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3389/fendo.2024.1346669

Gut microbiota and therapy for obesity and type 2 diabetes.

Fuente:Frontiers in Endocrinology

Tipo de trabajo:Revisión

Extracto: This review aims to provide insights into the evolving landscape of obesity management and the potential of microbiota-based approaches in addressing this pressing global health challenge.

Claves:bariatric surgery, gut microbiota, obesity, pharmacotherapy, type 2 diabetes

Cita:Front Endocrinol (Lausanne) 2024; 15 : 1333778.

Autor/es:Zhang, Luyao (a)
Wang, Pai (b)

institución:(a) Department of Gastrocolorectal Surgery, General Surgery Center, The First Hospital of Jilin University, Changchun, Jilin, China.
(b) Section of Endocrinology, Department of Internal Medicine, School of Medicine, Yale University, New Haven, CT, United States.

Conflicto:The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3389/fendo.2024.1333778

Association between gut microbiota and onset of type 2 diabetes mellitus: a two-sample Mendelian randomization study.

Association between gut microbiota and onset of type 2 diabetes mellitus: a two-sample Mendelian randomization study.

Fuente:Frontiers in Cellular and Infection Microbiology

Tipo de trabajo:Metanálisis

Extracto: GM had a potential causal association with T2DM, especially species faecis, finegoldii, and longum. Further studies are still needed to clarify certain results that are contradictory with previous findings.

Claves:Mendelian randomization, causal association, gut microbiota, species, type 2 diabetes mellitus

Cita:Front Cell Infect Microbiol 2024; 14 : 1327032.

Autor/es:Zhang, Hongyan (a)
Ma, Li (b)

institución:(a) Department of Traditional Chinese Medicine, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.
(b) Shaanxi Key Laboratory of Research on Traditional Chinese Medicine Physical Constitution and Diseases Prevention and Treatment, Shaanxi University of Chinese Medicine, Xianyang, Shaanxi, China.

Conflicto:The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3389/fcimb.2024.1327032

Emerging research themes in maternal hypothyroidism: a bibliometric exploration.

Emerging research themes in maternal hypothyroidism: a bibliometric exploration.

Fuente:Frontiers in Immunology

Tipo de trabajo:Guía

Extracto: This study unveils developmental trends, global collaboration patterns, foundational knowledge, and emerging frontiers in Maternal Hypothyroidism. Over 30 years, research has predominantly focused on aspects like diagnosis, treatment guidelines, thyroid function during pregnancy, and postpartum outcomes, with a central emphasis on the correlation between maternal and fetal health.

Claves:CiteSpace, VOSviewer, bibliometrics, emerging topics, maternal hypothyroidism, research focus, visualization

Cita:Front Immunol 2024; 15 : 1370707.

Autor/es:Chen, Ailing (a)
Luo, Zouqing (b)

institución:(a) Research Institute for Reproductive Health and Genetic Diseases, Women's Hospital of Jiangnan University, Wuxi Maternity and Child Health Care Hospital, Wuxi, China.
(b) Department of Obstetrics, Women's Hospital of Jiangnan University, Wuxi Maternity and Child Health Care Hospital, Wuxi, China.

Conflicto:The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3389/fimmu.2024.1370707

Differences in F pocket impact on HLA I genetic associations with autoimmune diabetes.

Fuente:Frontiers in Immunology

Extracto: Our work uncovers that specific polymorphisms in HLA I molecules potentially influence their susceptibility to T1D.

Claves:HLA class I, antigen presentation, autoimmune diabetes, inflammation, peptide binding, polymorphism

Cita:Front Immunol 2024; 15 : 1342335.

Autor/es:Ren, Xu (a)
Amarajeewa, A W Peshala (b)

institución:(a) Department of Urology, Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi, China.
(b) Core Research Laboratory, Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi, China.

Conflicto:The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3389/fimmu.2024.1342335

Emergence of De Novo Conditions Following Remission of Cushing Syndrome

Emergence of De Novo Conditions Following Remission of Cushing Syndrome

Fuente:Endocrinology, Diabetes & Metabolism

Tipo de trabajo:Revisión

Extracto: Our scoping review identified several cases of de novo conditions emerging following the remission of Cushing syndrome. They occurred mostly in women and within the year following remission. Clinicians should remain aware that new symptoms, particularly in the first year following the treatment of Cushing syndrome, may be manifestations of a wide range of conditions aside from adrenal insufficiency or glucocorticoid withdrawal syndrome.

Claves:Cushing syndrome, adult, autoimmune diseases, glucocorticoids, humans, sarcoidosis, thyroiditis

Cita:Endocrinol Diabetes Metab 2024 May; 7 (3) : e00476.

Autor/es:Desgagnés, Noémie (a)
Senior, Laura (b)

institución:(a) Department of Medicine, University of Calgary, Calgary, Alberta, Canada.
(b) Department of Medicine, University of Calgary, Calgary, Alberta, Canada.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe impreso

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1002/edm2.476

Bone canonical Wnt signaling is downregulated in type 2 diabetes and associates with higher advanced glycation end-products (AGEs) content and reduced bone strength.

Fuente:Elife

Extracto: These findings suggest that Wnt signaling and AGEs could be the main determinants of bone fragility in T2D.

Claves:AGEs, Wnt signaling, biochemistry, bone, chemical biology, diabetes, histomorphometry, human, medicine

Cita:Elife 2024 Apr 10; 12

Autor/es:Leanza, Giulia (a)
Cannata, Francesca (b)

institución:(a) Department of Medicine and Surgery, Research Unit of Endocrinology and Diabetes, Università Campus Bio-Medico di Roma, Via Alvaro del Portillo, Roma, Italy.
(b) Operative Research Unit of Osteometabolic and Thyroid Diseases, Fondazione Policlinico Universitario Campus Bio-Medico, Via Alvaro del Portillo, Roma, Italy.

Conflicto:GL, FC, MF, CP, VV, FT, NP, GV, AP, RS, FZ, AB, ES, ST, RC, MM, RP, NN No competing interests declared

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.7554/eLife.90437

High-resolution melt curve analysis: An approach for variant detection in the TPO gene of congenital hypothyroid patients in Bangladesh.

High-resolution melt curve analysis: An approach for variant detection in the TPO gene of congenital hypothyroid patients in Bangladesh.

Fuente:Plos One

Extracto: In conclusion, HRM-based molecular technique targeting variants c.1117G>T, c.1193G>C, and c.2173A>C could be used as a high throughput, rapid, reliable, and cost-effective screening approach for the detection of all common mutations in TPO gene in Bangladeshi patients with dyshormonogenesis.

Cita:PLoS One 2024; 19 (4) : e0293570.

Autor/es:Begum, Mst Noorjahan (a)
Mahtarin, Rumana (b)

institución:(a) Department of Genetic Engineering & Biotechnology, University of Dhaka, Dhaka, Bangladesh.
(b) Institute for Developing Science and Health Initiatives (ideSHi), ECB Chattar, Mirpur, Dhaka, Bangladesh.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:EE.UU.

Sitio web:http://dx.doi.org/10.1371/journal.pone.0293570

Independent and interactive associations of heart rate and obesity with type 2 diabetes mellites: A population-based study.

Independent and interactive associations of heart rate and obesity with type 2 diabetes mellites: A population-based study.

Fuente:Journal of Diabetes

Extracto: High HR was in interaction with obesity, associating with prevalence of T2DM. The newly subdivided risk threshold for HR with T2DM might be HR > 88 beats/minute.

Claves:heart rate, interactive effects, obesity, type 2 diabetes mellites

Cita:J Diabetes 2024 Apr; 16 (4) : e13529.

Autor/es:Zhu, Tianxin (a)
Chen, Qingyu (b)

institución:(a) Department of Endocrinology, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, China.
(b) Health Examination Center, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, China.

Formato:Informe impreso

Idioma:Inglés

País de fuente:Australia

Sitio web:http://dx.doi.org/10.1111/1753-0407.13529

Association of obstructive sleep apnea symptoms with all-cause mortality and cause-specific mortality in adults with or without diabetes

Fuente:Journal of Diabetes

Tipo de trabajo:Estudio de cohortes

Extracto: The relationship between OSAS and mortality differed among participants with or without diabetes. Individualized clinical treatment plans should be developed in clinical practice to reduce the risk of death for patients with different metabolic conditions.

Claves:NHANES, diabetes, mortality, obstructive sleep apnea syndrome

Cita:J Diabetes 2024 Apr; 16 (4) : e13538.

Autor/es:Zhang, Qian (a)
Zhang, Qi (b)

institución:(a) Department of General Practice, Affiliated Hospital of Weifang Medical University, Weifang, China.
(b) Department of Endocrinology and Metabolism, Affiliated Hospital of Weifang Medical University, Weifang, China.

Formato:Informe impreso

Idioma:Inglés

País de fuente:Australia

Sitio web:http://dx.doi.org/10.1111/1753-0407.13538

Association of advanced glycation end products with ear lobe crease: A cross-sectional study.

Fuente:Journal of Diabetes

Extracto: ELC is associated with coronary heart disease, and the SAF-AGE has a potential role in ELC development in elder people.

Claves:advanced glycation end products, cardiovascular disease, ear lobe crease, type 2 diabetes

Cita:J Diabetes 2024 Apr; 16 (4) : e13548.

Autor/es:Wang, Yuepeng (a)
Xin, Yu (b)

institución:(a) Department of Endocrinology, The First Medical Center of Chinese PLA General Hospital, Beijing, China.
(b) School of Medicine, Nankai University, Tianjin, China.

Formato:Informe impreso

Idioma:Inglés

País de fuente:Australia

Sitio web:http://dx.doi.org/10.1111/1753-0407.13548

Traditional and emerging strategies using hepatocytes for pancreatic regenerative medicine.

Fuente:Journal of Diabetes

Extracto: In addition, clustered regularly interspaced short palindromic repeats (CRISPR)/Cas9 gene editing technology has brought new opportunities and challenges to the development of organoid technology.

Claves:CRISPR/Cas9, epatocytes, organoids, regenerative medicine

Cita:J Diabetes 2024 Apr; 16 (4) : e13545.

Autor/es:Liu, Shuang (a)
Zhang, YuYing (b)

institución:(a) Department of Metabolism and Endocrinology, the Second Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang, China.
(b) Department of Metabolism and Endocrinology, the Second Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang, China.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe impreso

Idioma:Inglés

País de fuente:Australia

Sitio web:http://dx.doi.org/10.1111/1753-0407.13545

Advanced multifunctional hydrogels for diabetic foot ulcer healing: Active substances and biological functions.

Fuente:Journal of Diabetes

Tipo de trabajo:Revisión

Extracto: Hydrogels were classified into carrier hydrogels and self-functioning hydrogels in this review. Besides, the functions and components of existing hydrogels were clarified to provide assistance for future researches and clinical applications.

Claves:biological functions, classification, diabetic foot ulcer, hydrogels, pathogenesis

Cita:J Diabetes 2024 Apr; 16 (4) : e13537.

Autor/es:Li, Yuetong (a)
Leng, Yuxin (b)

institución:(a) Department of Endocrinology, The Eighth Affiliated Hospital, Sun Yat-sen University, Shenzhen, China.
(b) Department of Critical Care Medicine, Peking University Third Hospital, Beijing, China.

Conflicto:The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Formato:Informe impreso

Idioma:Inglés

País de fuente:Australia

Sitio web:http://dx.doi.org/10.1111/1753-0407.13537

Comparing Equil patch versus traditional catheter insulin pump in type 2 diabetes using continuous glucose monitoring metrics and profiles.

Fuente:Journal of Diabetes

Tipo de trabajo:Estudio clínico

Extracto: The Equil patch insulin pump was similar to the traditional MMT-712 insulin pump in terms of glycemic control. Equil patch insulin pump is a reliable tool for glycemic management of diabetes mellitus.

Claves:T2DM, continuous glucose monitoring, patch insulin pump

Cita:J Diabetes 2024 Apr; 16 (4) : e13536.

Autor/es:Li, Yu-Jiao (a)
Shao, Zi-Yue (b)

institución:(a) Department of Endocrinology, Nanjing First Hospital, Nanjing Medical University, Nanjing, China.
(b) Department of Endocrinology, Nanjing First Hospital, Nanjing Medical University, Nanjing, China.

Formato:Informe impreso

Idioma:Inglés

País de fuente:Australia

Sitio web:http://dx.doi.org/10.1111/1753-0407.13536

Novel T cell exhaustion gene signature to predict prognosis and immunotherapy response in thyroid carcinoma from integrated RNA-sequencing analysis.

Novel T cell exhaustion gene signature to predict prognosis and immunotherapy response in thyroid carcinoma from integrated RNA-sequencing analysis.

Fuente:Scientific Reports

Extracto: Therapeutic strategies that target SPP1(+) macrophages, CD14(+) monocytes, and the SPP1-CD44 and MIF-CD74 axes may potentially improve the prognosis and amplify the immunotherapy response in THCA patients.

Claves:Gene signature, Immunotherapy, Single-cell RNA-sequencing, T cell exhaustion, Thyroid carcinoma, Tumor-associated macrophage

Cita:Sci Rep 2024 Apr 10; 14 (1) : 8375.

Autor/es:Li, Yang (a)
Wang, Zhen (b)

institución:(a) Department of Endocrinology, First Affiliated Hospital of Anhui Medical University, Hefei, China.
(b) Department of Endocrinology, First Affiliated Hospital of Anhui Medical University, Hefei, China.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1038/s41598-024-58419-7

Cannabidiol exerts multitarget immunomodulatory effects on PBMCs from individuals with psoriasis vulgaris.

Cannabidiol exerts multitarget immunomodulatory effects on PBMCs from individuals with psoriasis vulgaris.

Fuente:Frontiers in Immunology

Extracto: These data uncover new potential immunomodulatory properties of this cannabinoid suggesting a possible therapeutic action in the treatment of multiple inflammatory skin diseases.

Claves:CBD, dendritic cells, macrophage, monocyte, natural killer, psoriasis

Cita:Front Immunol 2024; 15 : 1373435.

Autor/es:Pagano, Cristina (a)
Ciaglia, Elena (b)

institución:(a) Department of Molecular Medicine and Medical Biotechnology, University of Naples Federico II, Naples, Italy.
(b) Department of Medicine, Surgery and Dentistry "Scuola Medica Salernitana", University of Salerno, Baronissi, Italy.

Conflicto:The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3389/fimmu.2024.1373435

The fatal contribution of serine protease-related genetic variants to COVID-19 outcomes.

Fuente:Frontiers in Immunology

Extracto: Additionally, rs2227692 SERPINE1 could participate in hypercoagulable conditions in critical COVID-19 patients, and this genetic variant could contribute to the identification of new pharmacological targets and treatment strategies to block the inhibition of TMPRSS2 entry into SARS-CoV-2.

Claves:COVID-19, Polymorphism, SARS-CoV-2, SERPINE1, TMPRSS2

Cita:Front Immunol 2024; 15 : 1335963.

Autor/es:Martínez-Gómez, Laura Edith (a)
Martinez-Armenta, Carlos (b)

institución:(a) Laboratorio de Gerociencias, Dirección General, Departamento de Reconstrucción Articular, Laboratorio Facilitador, Instituto Nacional de Rehabilitación Luis Guillermo Ibarra Ibarra, Secretaría de Salud, Mexico City, Mexico.
(b) Laboratorio de Gerociencias, Dirección General, Departamento de Reconstrucción Articular, Laboratorio Facilitador, Instituto Nacional de Rehabilitación Luis Guillermo Ibarra Ibarra, Secretaría de Salud, Mexico City, Mexico.

Conflicto:The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. The author(s) declared that they were an editorial board member of Frontiers, at the time of submission. This had no impact on the peer review process and the final decision.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3389/fimmu.2024.1335963

Five percent weight loss is a significant 1-year predictor and an optimal 5-year cut-off for reducing the number of obesity-related cardiovascular disease risk components: the Japan Obesity and Metabolic Syndrome Study.

Five percent weight loss is a significant 1-year predictor and an optimal 5-year cut-off for reducing the number of obesity-related cardiovascular disease risk components: the Japan Obesity and Metabolic Syndrome Study.

Fuente:Frontiers in Endocrinology

Extracto: A weight loss of ≥5.0% at 1 year and ≥7.5% at 5 years could reduce the number of obesity-related CVD risk components in patients with obesity.

Claves:5-year follow-up, cohort study, metabolic syndrome, obesity, weight loss

Cita:Front Endocrinol (Lausanne) 2024; 15 : 1343153.

Autor/es:Yamakage, Hajime (a)
Jo, Takaaki (b)

institución:(a) Department of Endocrinology, Metabolism, and Hypertension Research, Clinical Research Institute, NHO Kyoto Medical Center, Kyoto, Japan.
(b) Department of General Internal Medicine, Fushimi Momoyama General Hospital, Kyoto, Japan.

Conflicto:The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. The author(s) declared that they were an editorial board member of Frontiers, at the time of submission. This had no impact on the peer review process and the final decision MT is an... Editorial Board Member of this journal but was not involved in the peer-review process nor had access to any information regarding its peer-review.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3389/fendo.2024.1343153