Cyto-Histological Profile of MicroRNAs as Diagnostic Biomarkers in Differentiated Thyroid Carcinomas.

Cyto-Histological Profile of MicroRNAs as Diagnostic Biomarkers in Differentiated Thyroid Carcinomas.

Fuente:Genes

Extracto: The association between the miRNAs expression profile and genetic alterations can be advantageous for an accurate diagnosis of DTCs/PTCs in FNAC.

Claves:BRAF, RAS, TERTp, differentiated thyroid carcinoma, genetic mutations, miR-146b, miR-15a, miR-221, miR-222, microRNAs, papillary thyroid carcinoma

Cita:Genes (Basel) 2024 Mar 21; 15 (3)

Autor/es:Matos, Maria de Lurdes (a)
Pinto, Mafalda (b)

institución:(a) Department of Endocrinology, Diabetes and Metabolism, Hospital Curry Cabral, Unidade Saúde Local São José, Centro Clínico e Académico de Lisboa, 1050-166 Lisbon, Portugal.
(b) Institute for Research & Innovation in Health (i3S), Instituto de Patologia e Imunologia Molecular da Universidade do Porto (IPATIMUP), 4200-135 Porto, Portugal.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3390/genes15030389

Alterations of the Adipo-Myokine Irisin in Sepsis and Septic Shock: Diagnostic and Prognostic Implications.

Alterations of the Adipo-Myokine Irisin in Sepsis and Septic Shock: Diagnostic and Prognostic Implications.

Fuente:Biomolecules

Extracto: Irisin may be a promising diagnostic and prognostic sepsis biomarker; nevertheless, larger studies are needed to explore its role in sepsis.

Claves:adipokine, biomarker, critically ill, irisin, mortality, myokine, sepsis, septic shock

Cita:Biomolecules 2024 Feb 29; 14 (3)

Autor/es:Karampela, Irene (a)
Vallianou, Natalia G (b)

institución:(a) Second Department of Critical Care, Attikon General University Hospital, Medical School, National and Kapodistrian University of Athens, 1 Rimini St., Haidari, 12462 Athens, Greece.
(b) Department of Biological Chemistry, Medical School, National and Kapodistrian University of Athens, 75 Mikras Asias St., Goudi, 11527 Athens, Greece.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3390/biom14030291

Intersections of Fibrodysplasia Ossificans Progressiva and Traumatic Heterotopic Ossification.

Fuente:Biomolecules

Extracto: As such, it is necessary to draw on advancements made in the study of tHO and gHO to better diagnose, comprehend, prevent, and treat both.

Claves:ACVR2, ALK2, ectopic bone, fibrodysplasia ossificans progressiva, heterotopic ossification, trauma

Cita:Biomolecules 2024 Mar 14; 14 (3)

Autor/es:Juan, Conan (a)
Bancroft, Alec C (b)

institución:(a) Center for Organogenesis, Regeneration, and Trauma, Department of Surgery, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
(b) Center for Organogenesis, Regeneration, and Trauma, Department of Surgery, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.

Conflicto:All authors have no relevant conflicts of interest to disclose.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3390/biom14030349

Immunologic Aspects in Fibrodysplasia Ossificans Progressiva.

Fuente:Biomolecules

Tipo de trabajo:Revisión

Extracto: Future research focusing on the identification of novel inflammatory targets will help support the testing of potential therapies for FOP and other related conditions.

Claves:cytokines, fibrodysplasia ossificans progressiva (FOP), heterotopic ossification, immune activation, inflammation, macrophages

Cita:Biomolecules 2024 Mar 16; 14 (3)

Autor/es:Diolintzi, Anastasia (a)
Pervin, Mst Shaela (b)

institución:(a) Division of Endocrinology and Metabolism, Department of Medicine, the Institute for Human Genetics, the Program in Craniofacial Biology, University of California, San Francisco, CA 94143, USA.
(b) Division of Endocrinology and Metabolism, Department of Medicine, the Institute for Human Genetics, the Program in Craniofacial Biology, University of California, San Francisco, CA 94143, USA.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3390/biom14030357

Association of Endogenous Testosterone with Physical Fitness Measures during Firefighter Occupational Health Evaluations.

Association of Endogenous Testosterone with Physical Fitness Measures during Firefighter Occupational Health Evaluations.

Fuente:International Journal of Environmental Research and Public Health

Extracto: Low TT and poor PF are important components of FFs' CM risk profile, and there is potential benefit to considering TT screening as part of a comprehensive occupational health program that manages performing medical evaluations and provides education and preventative programming.

Claves:cardiometabolic, cardiovascular, public safety, risk, workforce

Cita:Int J Environ Res Public Health 2024 Feb 27; 21 (3)

Autor/es:Porto, Luiz Guilherme Grossi (a)
Soares, Edgard M K V K (b)

institución:(a) Study Group on Exercise and Physical Activity Physiology and Epidemiology (GEAFS), Exercise Physiology Laboratory, Faculty of Physical Education, University of Brasilia-UnB, Brasilia 70910-900, Brazil.
(b) Study Group on Exercise and Physical Activity Physiology and Epidemiology (GEAFS), Exercise Physiology Laboratory, Faculty of Physical Education, University of Brasilia-UnB, Brasilia 70910-900, Brazil.

Conflicto:DLS served as a consultant in cases involving firefighters’ cardiac health. The remaining authors have no disclosures to report.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3390/ijerph21030274

Oral Health-Related Quality of Life in Italian Children and Adolescents Living with Bone Dysplasia: A Cross-Sectional Study.

Fuente:International Journal of Environmental Research and Public Health

Extracto: Based on these findings, children suffering from BD experience poorer OHRQoL than their healthy peers, suggesting that oral and dental issues may be of special importance for the socio-psychological well-being of these growing individuals.

Claves:COHIP, OHIP-14, SF-CPQ, bone dysplasia, children, oral health-related quality of life, rare diseases

Cita:Int J Environ Res Public Health 2024 Mar 6; 21 (3)

Autor/es:Defabianis, Patrizia (a)
Ninivaggi, Rossella (b)

institución:(a) Department of Surgical Sciences, C.I.R. Dental School, University of Turin, 10126 Turin, Italy.
(b) Department of Surgical Sciences, C.I.R. Dental School, University of Turin, 10126 Turin, Italy.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3390/ijerph21030306

Association between Albumin Alterations and Renal Function in Patients with Type 2 Diabetes Mellitus.

Association between Albumin Alterations and Renal Function in Patients with Type 2 Diabetes Mellitus.

Fuente:International Journal of Molecular Sciences

Extracto: Importantly, according to the multivariate logistic regression analysis, the eHA was identified as an independent predictor of DKD.

Claves:diabetic kidney disease, effective albumin, high-resolution mass spectrometry, oxidative damage, reduced albumin, structural alterations

Cita:Int J Mol Sci 2024 Mar 9; 25 (6)

Autor/es:Nugnes, Marta (a)
Baldassarre, Maurizio (b)

institución:(a) Department of Pharmacy and Biotechnology, Alma Mater Studiorum University of Bologna, 40126 Bologna, Italy.
(b) Unit of Semeiotics, Liver and Alcohol-Related Diseases, IRCCS Azienda Ospedaliero-Universitaria di Bologna, 40138 Bologna, Italy.

Conflicto:The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3390/ijms25063168

The Impact of Metabolic Memory on Immune Profile in Young Patients with Uncomplicated Type 1 Diabetes.

Fuente:International Journal of Molecular Sciences

Extracto: These findings also suggest that both metabolic memory and inflammation contribute to the abnormal lipid profile in patients with type 1 diabetes.

Claves:anti-inflammatory cytokines, lipids, metabolic memory, pro-inflammatory cytokines, type 1 diabetes mellitus, young diabetics

Cita:Int J Mol Sci 2024 Mar 10; 25 (6)

Autor/es:Neubauer-Geryk, Jolanta (a)
Wielicka, Melanie (b)

institución:(a) Clinical Physiology Unit, Medical Simulation Centre, Medical University of Gdańsk, 80-204 Gdańsk, Poland.
(b) Clinical Physiology Unit, Medical Simulation Centre, Medical University of Gdańsk, 80-204 Gdańsk, Poland.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3390/ijms25063190

Serum Expression of miR-23a-3p and miR-424-5p Indicate Specific Polycystic Ovary Syndrome Phenotypes: A Pilot Study.

Fuente:International Journal of Molecular Sciences

Extracto: Understanding the differential hormonal and miRNA profiles across PCOS phenotypes is important to improve the pathophysiological understanding of PCOS heterogeneity.

Claves:PCOS phenotypes, Rotterdam criteria, hyperandrogenism, miRNA, polycystic ovary syndrome

Cita:Int J Mol Sci 2024 Mar 11; 25 (6)

Autor/es:Trummer, Olivia (a)
Hoeller, Jonas (b)

institución:(a) Department of Internal Medicine, Division of Endocrinology and Diabetology, Medical University of Graz, 8036 Graz, Austria.
(b) Department of Internal Medicine, Division of Endocrinology and Diabetology, Medical University of Graz, 8036 Graz, Austria.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3390/ijms25063205

Metabolic Crossroads: Unveiling the Complex Interactions between Obstructive Sleep Apnoea and Metabolic Syndrome.

Fuente:International Journal of Molecular Sciences

Extracto: Additionally, the emergence of new drugs targeting obesity and unequivocal results of the available studies underscore the need for further exploration of the mechanisms linking MetS and OSA, all with the aim of improving outcomes in these patients.

Claves:diabetes mellitus, leptin, metabolic syndrome, obesity, obstructive sleep apnoea

Cita:Int J Mol Sci 2024 Mar 13; 25 (6)

Autor/es:Heffernan, Aisling (a)
Duplancic, Darko (b)

institución:(a) Department of Pathophysiology, University of Split School of Medicine, 21000 Split, Croatia.
(b) Department of Cardiology, University Hospital of Split, 21000 Split, Croatia.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3390/ijms25063243

Is There a Link between Thyroid Peroxidase Gene Promoter Polymorphisms and Autoimmune Thyroiditis in the Polish Population?

Fuente:International Journal of Molecular Sciences

Extracto: The studied TPO gene promoter polymorphisms did not show an association with susceptibility to AIT in the Caucasian Polish population, contrary to the results in Japanese patients.

Claves:TPOAb, autoantibodies, autoimmune thyroiditis, autoimmunity, polymorphism, thyroid peroxidase

Cita:Int J Mol Sci 2024 Mar 14; 25 (6)

Autor/es:Lacka, Katarzyna (a)
Maciejewski, Adam (b)

institución:(a) Department of Endocrinology, Metabolism and Internal Medicine, Poznan University of Medical Sciences, 60-355 Poznan, Poland.
(b) Department of Endocrinology, Metabolism and Internal Medicine, Poznan University of Medical Sciences, 60-355 Poznan, Poland.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3390/ijms25063312

Hsp70 and Calcitonin Receptor Protein in Extracellular Vesicles from Glioblastoma Multiforme: Biomarkers with Putative Roles in Carcinogenesis and Potential for Differentiating Tumor Types.

Fuente:International Journal of Molecular Sciences

Extracto: Our results encourage further research to assess Hsp70 and CTR as biomarkers for differentiating tumor forms and to determine their roles in GBM carcinogenesis.

Claves:CTR, EV, Hsp70, biomarkers, calcitonin receptor protein, chaperone system, early diagnosis, extracellular vesicles, glioblastoma multiforme, liquid biopsy

Cita:Int J Mol Sci 2024 Mar 18; 25 (6)

Autor/es:Alberti, Giusi (a)
Sánchez-López, Christian M (b)

institución:(a) Department of Biomedicine, Neurosciences and Advanced Diagnostics (BiND), University of Palermo, 90127 Palermo, Italy.
(b) Área de Parasitología, Departamento Farmacia y Tecnología Farmacéutica y Parasitología, Universitat de València, 46100 Burjassot, Spain.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3390/ijms25063415

In Vitro Modelling of Osteogenesis Imperfecta with Patient-Derived Induced Mesenchymal Stem Cells.

Fuente:International Journal of Molecular Sciences

Extracto: (4) In the current study, we have developed a multipotent in vitro iMSC model of OI patients and healthy controls able to differentiate into osteoblast-like cells.

Claves:Osteogenesis Imperfecta, bone, cell model, induced mesenchymal stem cells, osteoblast, skeletal dysplasia

Cita:Int J Mol Sci 2024 Mar 18; 25 (6)

Autor/es:Claeys, Lauria (a)
Zhytnik, Lidiia (b)

institución:(a) Department of Human Genetics, Amsterdam UMC Location Vrije Universiteit Amsterdam, 1081 HV Amsterdam, The Netherlands.
(b) Rare Bone Disease Center Amsterdam, 1081 HV Amsterdam, The Netherlands.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3390/ijms25063417

Adherence to Mediterranean Diet, Dietary Salt Intake, and Susceptibility to Nephrolithiasis: A Case-Control Study.

Adherence to Mediterranean Diet, Dietary Salt Intake, and Susceptibility to Nephrolithiasis: A Case-Control Study.

Fuente:Nutrients

Extracto: In conclusion, high MD adherence and low salt intake are associated with a reduced NL susceptibility, both separately and in combination.

Claves:MEDILITE, MINISAL, dietary habits, nephrolithiasis

Cita:Nutrients 2024 Mar 9; 16 (6)

Autor/es:Abate, Veronica (a)
Vergatti, Anita (b)

institución:(a) Department of Clinical Medicine and Surgery, Federico II University, 80131 Naples, Italy.
(b) Department of Clinical Medicine and Surgery, Federico II University, 80131 Naples, Italy.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3390/nu16060783

Exploring the Influence of Insulin Resistance on Arterial Stiffness in Healthy Adults: From the Metabolic and Cardiovascular Health Insights of the EVasCu Study.

Fuente:Nutrients

Extracto: By examining this influence, we embark on an intriguing exploration of how these factors interplay in the human body.

Claves:adult, cardiovascular health, endocrinology, epidemiology, insulin resistance, metabolism, pulse wave analysis, vascular stiffness

Cita:Nutrients 2024 Mar 11; 16 (6)

Autor/es:Pascual-Morena, Carlos (a)
Cavero-Redondo, Iván (b)

institución:(a) Health and Social Research Center, Universidad de Castilla-La Mancha, 16071 Cuenca, Spain.
(b) Faculty of Nursing, Universidad de Castilla-La Mancha, 02006 Albacete, Spain.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3390/nu16060791

Randomised Controlled Trial of a Customised Text Messaging and Activity Monitor Program for Lifestyle Improvement after Gestational Diabetes.

Fuente:Nutrients

Extracto: In conclusion, no improvement in the diabetes risk factors occurred among the women receiving the text messaging intervention when affected by COVID-19 restrictions.

Claves:M-health, activity monitor, diabetes prevention, gestational diabetes, lifestyle program, randomised controlled trial, text-messaging

Cita:Nutrients 2024 Mar 13; 16 (6)

Autor/es:Cheung, Ngai Wah (a)
Simmons, David (b)

institución:(a) Westmead Applied Research Centre, Faculty of Medicine and Health, University of Sydney, Sydney, NSW 2006, Australia.
(b) Department of Diabetes and Endocrinology, Westmead Hospital, Sydney, NSW 2145, Australia.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3390/nu16060820

Classification of Vitamin D Status Based on Vitamin D Metabolism: A Randomized Controlled Trial in Hypertensive Patients.

Fuente:Nutrients

Tipo de trabajo:Estudio aleatorizado y controlado

Extracto: The clinical significance of functional vitamin D deficiency requires further evaluation in large vitamin D RCTs.

Claves:24,25-dihydroxyvitamin D, RCT, classification, deficiency, supplementation, vitamin D, vitamin D metabolite ratio

Cita:Nutrients 2024 Mar 14; 16 (6)

Autor/es:Zelzer, Sieglinde (a)
Meinitzer, Andreas (b)

institución:(a) Clinical Institute of Medical and Chemical Laboratory Diagnostics, Medical University of Graz, 8036 Graz, Austria.
(b) Clinical Institute of Medical and Chemical Laboratory Diagnostics, Medical University of Graz, 8036 Graz, Austria.

Conflicto:Winfried März was employed by the company SYNLAB Academy, Synlab Holding Deutschland GmbH. The remaining authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. The funders had no role in the design of the study; in the collection, analyses, or interpretation of data;... ; in the writing of the manuscript; or in the decision to publish the results.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3390/nu16060839

Effects of Mindful Eating in Patients with Obesity and Binge Eating Disorder.

Fuente:Nutrients

Extracto: ME improved anthropometric data, episodes of binge eating, body image dissatisfaction, eating habits, and quality of life in participants with obesity and BED in the short-term. However, an extension of the project will be necessary to analyze the impact of the intervention in the long-term.

Claves:binge eating disorder, eating disorders, mindful eating, nutritional intervention, obesity

Cita:Nutrients 2024 Mar 19; 16 (6)

Autor/es:Minari, Tatiana Palotta (a)
Araújo-Filho, Gerardo Maria de (b)

institución:(a) Department of Psychiatry, State Faculty of Medicine of São José do Rio Preto (FAMERP), São José do Rio Preto 15090-000, SP, Brazil.
(b) Department of Hypertension, State Faculty of Medicine of São José do Rio Preto (FAMERP), São José do Rio Preto 15090-000, SP, Brazil.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3390/nu16060884

Nutritional and Morphofunctional Assessment of Post-ICU Patients with COVID-19 at Hospital Discharge: NutriEcoMuscle Study.

Fuente:Nutrients

Extracto: The NutriEcoMuscle study highlights the need for a thorough nutritional and morphofunctional status assessment of post-ICU patients.

Claves:COVID-19, SARS-CoV-2, bioelectrical impedance analysis, body composition, functional status, intensive care units, malnutrition, nutrition assessment, nutritional status, nutritional ultrasonography

Cita:Nutrients 2024 Mar 19; 16 (6)

Autor/es:Joaquín, Clara (a)
Bretón, Irene (b)

institución:(a) Department of Endocrinology and Nutrition, Hospital Germans Trias i Pujol, Carretera del Canyet, S/N, 08916 Badalona, Spain.
(b) Department of Endocrinology and Nutrition, Hospital General Universitario Gregorio Marañón, C/Dr. Esquerdo, 46, 28007 Madrid, Spain.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3390/nu16060886

Analysis of Fluid Balance and Urine Values in Elite Soccer Players: Impact of Different Environments, Playing Positions, Sexes, and Competitive Levels.

Fuente:Nutrients

Extracto: In conclusion, differences in the fluid balance were observed based on the climatic conditions, competitive level, and sex.

Claves:dehydration, fluid balance, football, hydration, soccer, sweat rate

Cita:Nutrients 2024 Mar 21; 16 (6)

Autor/es:Sebastiá-Rico, Jaime (a)
Soriano, Jose M (b)

institución:(a) Area of Nutrition, University Clinic of Nutrition, Physical Activity and Physiotherapy (CUNAFF), Lluís Alcanyís Foundation-University of Valencia, 46020 Valencia, Spain.
(b) Food & Health Lab, Institute of Materials Science, University of Valencia, 46980 Paterna, Spain.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3390/nu16060903