Targeting the Hallmarks of Aging with Vitamin D: Starting to Decode the Myth.

Targeting the Hallmarks of Aging with Vitamin D: Starting to Decode the Myth.

Fuente:Nutrients

Extracto: However, more investigations are needed to clarify the pleiotropic effects of VitD and its impact on the hallmark of aging, hopefully highlighting the courses for translational applications and potential clinical conclusions.

Claves:aging, clinical studies, hallmarks of aging, vitamin D

Cita:Nutrients 2024 Mar 21; 16 (6)

Autor/es:Ruggiero, Carmelinda (a)
Tafaro, Laura (b)

institución:(a) Geriatric and Orthogeriatric Units, Division Gerontology and Geriatrics, Department of Medicine and Surgery, University of Perugia, 06156 Perugia, Italy.
(b) Division of Internal Medicine, Department of Molecular Medicine, Sapienza University of Rome, 00185 Rome, Italy.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3390/nu16060906

Nutritional Management of Athletes with Type 1 Diabetes

Fuente:Nutrients

Tipo de trabajo:Revisión

Extracto: Micronutrient needs and nutritional supplement effects are also highlighted in this paper.

Claves:carbohydrates, nutritional supplements, physical activity, proteins, type 1 diabetes mellitus

Cita:Nutrients 2024 Mar 21; 16 (6)

Autor/es:Cavallo, Massimiliano (a)
De Fano, Michelantonio (b)

institución:(a) Department of Medicine and Surgery, University of Perugia, Unit of Internal Medicine, Terni University Hospital, Piazzale Tristano Di Joannuccio, 1, 05100 Terni, Italy.
(b) Section of Endocrinology and Metabolism, Department of Medicine and Surgery, University of Perugia Medical School, 06132 Perugia, Italy.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3390/nu16060907

The emerging role and clinical significance of circRNAs in papillary thyroid cancer.

The emerging role and clinical significance of circRNAs in papillary thyroid cancer.

Fuente:Frontiers in Endocrinology

Extracto: It represents a promising avenue for advancing the diagnosis, management, and treatment of PTC.

Claves:biomarker, carcinogenesis, circRNA, papillary thyroid cancer, signaling pathway

Cita:Front Endocrinol (Lausanne) 2024; 15 : 1351776.

Autor/es:Ma, Jing (a)
Xu, Jing (b)

institución:(a) The First Clinical Medical School, Lanzhou University, Lanzhou, Gansu, China.
(b) Department of Endocrinology, Gansu Provincial Hospital, Lanzhou, Gansu, China.

Conflicto:The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3389/fendo.2024.1351776

Metabolomic response to acute resistance exercise in healthy older adults by 1H-NMR.

Metabolomic response to acute resistance exercise in healthy older adults by 1H-NMR.

Fuente:Plos One

Tipo de trabajo:Estudio clínico

Extracto: This study demonstrates that while many exercise-responsive metabolites change similarly in young and older adults, several demonstrate age-dependent changes even in the absence of evidence of sarcopenia or frailty. TRIAL REGISTRATION: Clinical trial registry: ClinicalTrials.gov NCT03350906.

Cita:PLoS One 2024; 19 (3) : e0301037.

Autor/es:Moosavi, Darya (a)
Vuckovic, Ivan (b)

institución:(a) Department of Internal Medicine, Endocrine Research Unit, Division of Endocrinology, Mayo Clinic, Rochester, MN, United States of America.
(b) Department of Biobehavioral Sciences, Teachers College, Columbia University, New York, NY, United States of America.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:EE.UU.

Sitio web:http://dx.doi.org/10.1371/journal.pone.0301037

Japanese clinical practice patterns of rituximab treatment for minimal change disease in adults 2021: A web-based questionnaire survey of certified nephrologists.

Fuente:Plos One

Extracto: This survey revealed the nephrologists' characteristics associated with RTX use, the barriers to RTX use, and the variation in the regimens for adult MCD in Japan.

Cita:PLoS One 2024; 19 (3) : e0299053.

Autor/es:Koizumi, Masahiro (a)
Ishimoto, Takuji (b)

institución:(a) Division of Nephrology, Endocrinology and Metabolism, Tokai University School of Medicine, Kanagawa, Japan.
(b) Department of Nephrology and Rheumatology, Aichi Medical University, Aichi, Japan.

Conflicto:We have read the journal’s policy and the authors of this manuscript have the following competing interests: Noriaki Kurita (Honoraria from GlaxoSmithKline). This does not alter our adherence to PLOS ONE policies on sharing data and materials.

Formato:Informe virtual

Idioma:Inglés

País de fuente:EE.UU.

Sitio web:http://dx.doi.org/10.1371/journal.pone.0299053

Enhanced predictive validity of integrative models for refractory hyperthyroidism considering baseline and early therapy characteristics

Enhanced predictive validity of integrative models for refractory hyperthyroidism considering baseline and early therapy characteristics

Fuente:Journal of Translational Medicine

Tipo de trabajo:Estudio de cohortes

Extracto: Integrating baseline and early therapy characteristics enhances the predictive capability for refractory GD outcomes. The study provides valuable insights into refining risk assessment and guiding personalized treatment decisions for GD patients.

Claves:Baseline characteristics, Drug dosage, Early therapy, Graves’ disease, Predictive model, Refractory

Cita:J Transl Med 2024 Mar 29; 22 (1) : 318.

Autor/es:Wang, Xinpan (a)
Li, Tiantian (b)

institución:(a) Department of Endocrinology, The First Affiliated Hospital of Nanjing Medical University, No.300, Guangzhou Road, Gulou District, Nanjing, Jiangsu, China.
(b) Department of Endocrinology, The First Affiliated Hospital of Nanjing Medical University, No.300, Guangzhou Road, Gulou District, Nanjing, Jiangsu, China.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1186/s12967-024-05129-3

Endocrine and non-endocrine causes of fatigue in adults with Neurofibromatosis type 1.

Endocrine and non-endocrine causes of fatigue in adults with Neurofibromatosis type 1.

Fuente:Frontiers in Endocrinology

Tipo de trabajo:Revisión

Extracto: Endocrine and non-endocrine disorders were equally present in our cohort of NF1 adults with and without fatigue. This suggests that the high prevalence of fatigue in NF1 adults is not explained by these somatic disorders. An alternative explanation for fatigue might be deficits in cognitive functioning and other neuropsychological processes in NF1. Based on our results and review of the literature, we provide a clinical algorithm for the approach to fatigue in NF1 adults, including somatic and psychological assessment.

Claves:Neurofibromatosis type 1 (NF1), adult, endocrinology, fatigue, internal medicine

Cita:Front Endocrinol (Lausanne) 2023; 14 : 1119159.

Autor/es:Rosenberg, Anna G W (a)
Mochèl, Ké (b)

institución:(a) Department of Internal Medicine, Division of Endocrinology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, Netherlands.
(b) Department of Internal Medicine, Division of Endocrinology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, Netherlands.

Conflicto:The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3389/fendo.2023.1119159

Association between visfatin and periodontitis

Association between visfatin and periodontitis

Fuente:Peerj

Tipo de trabajo:Revisión sistemática

Extracto: This first-ever meta-analysis comparing visfatin levels between patients with periodontitis and healthy individuals suggests that this adipocytokine can be a diagnostic and therapeutic biomarker for periodontal disease.

Claves:Adipocytokine, Periodontitis, Visfatin

Cita:PeerJ 2024; 12 : e17187.

Autor/es:Li, Yaoqin (a)
Xin, Caihong (b)

institución:(a) Department of Stomatology, First Affiliated Hospital of Soochow University, Suzhou, China.
(b) Department of Endocrinology and Metabolism, Fourth People's Hospital of Shenyang, Shenyang, China.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:EE.UU.

Sitio web:http://dx.doi.org/10.7717/peerj.17187

Management of lower-extremity venous thromboembolism

Management of lower-extremity venous thromboembolism

Fuente:Cleveland Clinic Journal of Medicine

Tipo de trabajo:Revisión

Extracto: More evidence now supports the treatment of superficial vein thrombosis with anticoagulation in high-risk patients.

Cita:Cleve Clin J Med 2024 Apr 1; 91 (4) : 229-235.

Autor/es:Ziyadeh, Farah (a)
Mauer, Yael (b)

institución:(a) Department of Internal Medicine, Cleveland Clinic, Cleveland, OH.
(b) Department of Endocrinology and Metabolism, Cleveland Clinic, Cleveland, OH; Assistant Professor, Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Cleveland, OH mauery@ccf.org.

Formato:Informe virtual

Idioma:Inglés

País de fuente:EE.UU.

Sitio web:http://dx.doi.org/10.3949/ccjm.91a.22090

Blood leukocytes as a non-invasive diagnostic tool for thyroid nodules

Blood leukocytes as a non-invasive diagnostic tool for thyroid nodules

Fuente:Bmc Medicine

Tipo de trabajo:Estudio de cohortes

Extracto: This is the first study to demonstrate the potential of non-invasive blood leukocytes in diagnosing TNs, thereby making TN diagnosis and treatment more efficient in China.

Claves:Benign thyroid nodule, Blood leukocyte, DNA methylation, Malignant thyroid nodule, Methylation model

Cita:BMC Med 2024 Apr 2; 22 (1) : 147.

Autor/es:Wang, Feihang (a)
Zhao, Danyang (b)

institución:(a) Department of Interventional Radiology, Zhongshan Hospital, Fudan University, Shanghai, 200032, China.
(b) National Clinical Research Center for Interventional Medicine, Zhongshan Hospital, Fudan University, Shanghai, 200032, China.

Conflicto:WYX, YYL, QYH, CXG, RL, and ZXS were employed by company Singlera Genomics Ltd. The remaining authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1186/s12916-024-03368-1

Long-term surgical outcome and impact on daily life activities of strabismus surgery in thyroid-associated ophthalmopathy with and without previous orbital decompression.

Fuente:Head & Face Medicine

Tipo de trabajo:Revisión

Extracto: The results of our study showed that DS patients required almost twice the number of strabismus surgical procedures, a higher number of extraocular muscles recessed in the first surgery, and an increased need for prism lenses to correct the residual deviation compared to the NDS, but with similar long-term surgical outcomes.

Claves:Orbital decompression, Strabismus, Surgical outcome, Thyroid Associated Ophthalmopathy

Cita:Head Face Med 2024 Apr 1; 20 (1) : 22.

Autor/es:Roda, Matilde (a)
Valsecchi, Nicola (b)

institución:(a) Ophthalmology Unit, DIMEC, University of Bologna, Via Pelagio Palagi 9, 4038, Bologna, Italy. matilde.roda@hotmail.com.
(b) IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy. matilde.roda@hotmail.com.

Conflicto:The authors declare that they have no known competing financial interestsor personal relationships that could have appeared to influence the work reported in this paper.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1186/s13005-024-00423-3

The Potential of Exosomes for Osteoporosis Treatment

The Potential of Exosomes for Osteoporosis Treatment

Fuente:Drug Design, Development and Therapy

Tipo de trabajo:Revisión

Extracto: Recent years have seen a rise in interest in the role of exosomes in osteoporosis, which has given rise to innovative therapeutic approaches for the disease prevention and management.

Claves:exosomes, extracellular vesicles, osteoblast function, osteoclast function, osteoporosis

Cita:Drug Des Devel Ther 2024; 18 : 979-989.

Autor/es:He, Yinxi (a)
Chen, Yanxia (b)

institución:(a) Department of Orthopaedic Trauma, The Third Hospital of Shijiazhuang, Shijiazhuang, Hebei, 050000, People's Republic of China.
(b) Department of Endocrinology, The Second Hospital of Hebei Medical University, Shijiazhuang, Hebei, 050000, People's Republic of China.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Nueva Zelanda

Sitio web:http://dx.doi.org/10.2147/DDDT.S437596

Excessive Exogenous Gonadotropins and Genetic and Pregnancy Outcomes After Euploidy Embryo Transfer

Excessive Exogenous Gonadotropins and Genetic and Pregnancy Outcomes After Euploidy Embryo Transfer

Fuente:Jama Network Open

Tipo de trabajo:Estudio clínico aleatorizado

Extracto: AND RELEVANCE: In this study, excessive exogenous gonadotropin administration was associated with increased embryonic mosaicism and decreased cumulative live birth rate after euploid embryo transfer in couples with a good prognosis. These findings suggest that consideration should be given to minimizing exogenous gonadotropin dosage and limiting treatment duration to improve embryo outcomes and increase the live birth rate. TRIAL REGISTRATION: ClinicalTrials.gov Identifier: NCT03118141.

Cita:JAMA Netw Open 2024 Apr 1; 7 (4) : e244438.

Autor/es:Ni, Tianxiang (a)
Zhou, Wei (b)

institución:(a) Center for Reproductive Medicine, Shandong University, Jinan, Shandong, China.
(b) Key Laboratory of Reproductive Endocrinology of Ministry of Education, Shandong University, Jinan, Shandong, China.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:EE.UU.

Sitio web:http://dx.doi.org/10.1001/jamanetworkopen.2024.4438

Role of the gut microbiota and innate immunity in polycystic ovary syndrome: Current updates and future prospects.

Role of the gut microbiota and innate immunity in polycystic ovary syndrome: Current updates and future prospects.

Fuente:Journal of Cellular and Molecular Medicine

Extracto: In order to provide basis for prevention and treatment of PCOS based on gut microbiota.

Claves:PCOS, gut microbiota, hormone, obesity

Cita:J Cell Mol Med 2024 Apr; 28 (8) : e18258.

Autor/es:Zhou, Min (a)
Yu, Jing (b)

institución:(a) Department of Gynaecology, The Affiliated Hospital to Changchun University of Chinese Medicine, Changchun, Jilin, China.
(b) Department of Endocrinology, The Affiliated Hospital to Changchun University of Chinese Medicine, Changchun, Jilin, China.

Conflicto:The authors have no relevant financial or non‐financial interests to disclose.

Formato:Informe impreso

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1111/jcmm.18258

Mevalonate kinase-deficient THP-1 cells show a disease-characteristic pro-inflammatory phenotype.

Mevalonate kinase-deficient THP-1 cells show a disease-characteristic pro-inflammatory phenotype.

Fuente:Frontiers in Immunology

Extracto: MK-deficient THP-1 cells show the biochemical and pro-inflammatory phenotype of MKD and are a good model to study underlying disease mechanisms and therapeutic options of this autoinflammatory disorder.

Claves:autoinflammatory disorders, cytokines, hyper IgD syndrome, innate immune response, isoprenoid biosynthesis, mevalonate kinase deficiency

Cita:Front Immunol 2024; 15 : 1379220.

Autor/es:Politiek, Frouwkje A (a)
Turkenburg, Marjolein (b)

institución:(a) Laboratory Genetic Metabolic Diseases, Department of Laboratory Medicine, Amsterdam University Medical Centers, Location Academic Medical Center, Amsterdam, Netherlands.
(b) Amsterdam Gastroenterology Endocrinology Metabolism, Amsterdam, Netherlands.

Conflicto:The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3389/fimmu.2024.1379220

Clinicopathological and prognostic significance of VEGF, PDGF-B, and HER2/neu expression in gallbladder cancer.

Clinicopathological and prognostic significance of VEGF, PDGF-B, and HER2/neu expression in gallbladder cancer.

Fuente:Journal of Cancer Research and Therapeutics

Extracto: Overexpression of VEGF, PDGF-B, and HER2/neu might be possible prognostic biomarkers in GBC. Poor survival of VEGF and HER2/neu positive cases indicates the possibilities of using their blockers as therapeutic agents.

Cita:J Cancer Res Ther 2024 Jan 1; 20 (1) : 349-357.

Autor/es:Shukla, Pooja (a)
Mishra, Kumudesh (b)

institución:(a) Department of Translational Molecular Pathology, MD Anderson Cancer Center, Houston, TX, USA.
(b) Department of Neurology, Faculty of Medicine, Hadassah-Hebrew University Medical Center, Ein Kerem, Jerusalem, Israel.

Formato:Informe impreso

Idioma:Inglés

País de fuente:India

Sitio web:http://dx.doi.org/10.4103/jcrt.jcrt_1473_22

The causal relationship between gut microbiota and biliary tract cancer: comprehensive bidirectional Mendelian randomization analysis.

The causal relationship between gut microbiota and biliary tract cancer: comprehensive bidirectional Mendelian randomization analysis.

Fuente:Frontiers in Cellular and Infection Microbiology

Extracto: This investigation represents the inaugural identification of indicative data supporting either beneficial or detrimental causal relationships between gut microbiota and the risk of BTC, as determined through the utilization of MR methodologies. These outcomes could hold significance for the formulation of individualized therapeutic strategies aimed at BTC prevention and survival enhancement.

Claves:biliary tract cancer, comprehensive bidirectional mendelian randomization, genome-wide association study, gut microbiota, probiotics

Cita:Front Cell Infect Microbiol 2024; 14 : 1308742.

Autor/es:Wang, Kui (a)
Wang, Suijian (b)

institución:(a) Department of Gastroenterology, Ruijin Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.
(b) Department of Gastroenterology, The Affiliated Hospital of Kunming University of Science and Technology, The First People's Hospital of Yunnan Province, Kunming, China.

Conflicto:The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3389/fcimb.2024.1308742

The relationship between autoimmune thyroid disease, thyroid nodules and sleep traits: a Mendelian randomization study.

The relationship between autoimmune thyroid disease, thyroid nodules and sleep traits: a Mendelian randomization study.

Fuente:Frontiers in Endocrinology

Extracto: The results of our study reveal a notable cause-and-effect relationship between Getting up and Autoimmune hypothyroidism, indicating its potential role as a protective factor against this condition. However, no causal connection was observed between sleep traits and Graves' disease or Thyroid nodules.

Claves:GWAS, Graves’ disease, Mendelian randomization, hypothyroidism, thyroid nodules

Cita:Front Endocrinol (Lausanne) 2023; 14 : 1325538.

Autor/es:Wang, Suijian (a)
Wang, Kui (b)

institución:(a) Department of Endocrinology, The First Affiliated Hospital, School of Medicine, Shantou University, Shantou, China.
(b) Department of Gastroenterology, Ruijin Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.

Conflicto:The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3389/fendo.2023.1325538

Exposure to Polybrominated Diphenyl Ethers and Risk of All-Cause and Cause-Specific Mortality.

Exposure to Polybrominated Diphenyl Ethers and Risk of All-Cause and Cause-Specific Mortality.

Fuente:Jama Network Open

Tipo de trabajo:Estudio de cohortes

Extracto: AND RELEVANCE: In this nationally representative cohort study, PBDE exposure was significantly associated with an increased risk of cancer mortality. Further studies are needed to replicate the findings and determine the underlying mechanisms.

Cita:JAMA Netw Open 2024 Apr 1; 7 (4) : e243127.

Autor/es:Liu, Buyun (a)
Lehmler, Hans-Joachim (b)

institución:(a) Department of Nursing, The First Affiliated Hospital of USTC, Institute of Public Health Sciences, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui, China.
(b) Department of Occupational and Environmental Health, College of Public Health, University of Iowa, Iowa City.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:EE.UU.

Sitio web:http://dx.doi.org/10.1001/jamanetworkopen.2024.3127

Fertility and sexual activity in patients with Triple A syndrome.

Fertility and sexual activity in patients with Triple A syndrome.

Fuente:Frontiers in Endocrinology

Extracto: Our results contribute to still scarce knowledge on fertility in patients with Triple A syndrome and as well represents a foundation for further research on causes of infertility and possible treatment options.

Claves:Allgrove syndrome, ejaculatory dysfunction, erectile dysfunction, pregnancy, sexual activity

Cita:Front Endocrinol (Lausanne) 2024; 15 : 1357084.

Autor/es:Dumic, Katja K (a)
Heinrichs, Claudine (b)

institución:(a) Department of Paediatric Endocrinology and Diabetes, University Hospital Centre Zagreb, University of Zagreb, School of Medicine, Zagreb, Croatia.
(b) Université libre de Bruxelles (ULB), Hôpital Universitaire de Bruxelles (H.U.B), Hôpital Universitaire des Enfants Reine Fabiola (HUDERF) Paediatric Endocrinology Unit, Bruxelles, Belgium.

Conflicto:The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. The author(s) declared that they were an editorial board member of Frontiers, at the time of submission. This had no impact on the peer review process and the final decision.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3389/fendo.2024.1357084