Textos Completos Autorizados

Endocrinología y Metabolismo
SIIC selecciona textos completos de calidad y de reciente publicación en fuentes prestigiosas del mundo indizadas por SIIC Data Bases, capturadas en las mismas colecciones o en diversas bases especializadas.
La creciente cantidad de artículos con Acceso Abierto (Open Access) amplía la oferta de lectura pero a su vez también, entre tanta abundancia, complica al lector en su encuentro con los estudios fundamentales. Para facilitarlo, profesionales biomédicos de SIIC consultan diariamente una profusa cantidad de documentos que nutrirán Textos completos autorizados (TCA).

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Si bien la mayoría de los textos seleccionados corresponden a artículos originales, revisiones y guías, los lectores también encontrarán comentarios, entrevistas, notas periodísticas, cartas a autores u otros textos precursores de debates o aclaratorios.

Con una o todas las palabras
(escribir en inglés)
 
Ej.1: Adipokines Ej.2: Adipokines or Musculoskeletal
Con la frase exacta
(inglés)

Ej.3: Adipokines and Cardiovascular Systems
Con todas de las palabras
(inglés)

Ej.4: Adipokines and Cardiovascular and Systems
Sin las palabras
(inglés)

Ej.5: not Cardiovascular Systems

Medicina

Selección SIIC: 9 Mayo, 2024

Medicina

Primary hyperparathyroidism in pregnancy

Primary hyperparathyroidism in pregnancy

Fuente:Medicina

Tipo de trabajo:Caso clínico

Extracto: In most cases, parathyroidectomy is the treatment of choice.

Claves:cerebral venous thrombosis, hypercalcemia, parathyroid adenoma, preeclampsia, pregnancy, primary hyperparathyroidism

Cita:Medicina (B Aires) 2024; 84 (2) : 342-346.

Autor/es:Pereyra, Pilar de Las Mercedes (a)
Aciar, María de Los Ángeles (b)

institución:(a) Servicio de Endocrinología y Metabolismo, Hospital Público Materno Infantil de Salta, Salta, Argentina. E-mail: pilar_pereyra75@hotmail.com.
(b) Servicio de Endocrinología y Metabolismo, Hospital Público Materno Infantil de Salta, Salta, Argentina.

Formato:Informe impreso

Idioma:Inglés

País de fuente:Argentina

Sitio web:

Medicina

Selección SIIC: 9 Mayo, 2024

Medicina

[Multiple endocrine neoplasia and very early onset inflammatory bowel disease. An unexpected association].

[Multiple endocrine neoplasia and very early onset inflammatory bowel disease. An unexpected association].

Fuente:Medicina

Extracto: The presence of these two clinical entities cannot be attributed to a single genetic cause.

Claves:RET proto-oncogene, multiple endocrine neoplasia 2A, primary immunodeficiency, very early onset inflammatory bowel disease

Cita:Medicina (B Aires) 2024; 84 (2) : 347-350.

Autor/es:Rossi, Santiago I (a)
Baleani, Silvia (b)

institución:(a) Unidad 5, Clínica Médica, Hospital de Niños Ricardo Gutiérrez, Buenos Aires, Argentina. E-mail: santiagorossi.pediatria@gmail.com.
(b) Unidad 5, Clínica Médica, Hospital de Niños Ricardo Gutiérrez, Buenos Aires, Argentina.

Formato:Informe impreso

Idioma:spa

País de fuente:Argentina

Sitio web:

Fukushima journal of medical science

Selección SIIC: 9 Mayo, 2024

Fukushima journal of medical science

2023 Fukushima Medical University International Symposium on the Fukushima Health Management Survey, "Thinking Together about Health, Life, and our Future in Fukushima".

2023 Fukushima Medical University International Symposium on the Fukushima Health Management Survey, "Thinking Together about Health, Life, and our Future in Fukushima".

Fuente:Fukushima Journal of Medical Science

Extracto: The fifth annual symposium convened at FMU's Ekimae Campus on Saturday, 4 March 2023, with the theme, "Thinking Together about Health, Life and our Future in Fukushima."

Cita:Fukushima J Med Sci 2024; 70 (2) : 107-109.

Autor/es:Shimabukuro, Michio (a)
Kamiya, Kenji (b)

institución:(a) Department of Diabetes, Endocrinology and Metabolism, Fukushima Medical University School of Medicine.
(b) Radiation Medical Science Center for the Fukushima Health Management Survey, Fukushima Medical University.

Formato:Informe impreso

Idioma:Inglés

País de fuente:Japón

Sitio web:http://dx.doi.org/10.5387/fms.24-00007

Cell death & disease

Selección SIIC: 9 Mayo, 2024

Cell death & disease

Identification of a set of genes potentially responsible for resistance to ferroptosis in lung adenocarcinoma cancer stem cells.

Identification of a set of genes potentially responsible for resistance to ferroptosis in lung adenocarcinoma cancer stem cells.

Fuente:Cell Death & Disease

Extracto: Moreover, transcriptomic analyses highlighted a novel subset of genes commonly modulated in 3D spheroids and potentially capable of driving ferroptosis protection in LUAD-CSCs, thus allowing to better understand the mechanisms of CSC-mediated drug resistance in tumors.

Cita:Cell Death Dis 2024 Apr 29; 15 (4) : 303.

Autor/es:Ascenzi, Francesca (a)
Esposito, Antonella (b)

institución:(a) Translational Oncology Research Unit, IRCCS Regina Elena National Cancer Institute, Rome, Italy.
(b) Department of Clinical and Molecular Medicine, Sant' Andrea Hospital-Sapienza University of Rome, Rome, Italy.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1038/s41419-024-06667-w

BMC emergency medicine

Selección SIIC: 9 Mayo, 2024

BMC emergency medicine

Diastolic/systolic blood pressure ratio for predicting febrile children with sepsis and progress to septic shock in the emergency department.

Diastolic/systolic blood pressure ratio for predicting febrile children with sepsis and progress to septic shock in the emergency department.

Fuente:Bmc Emergency Medicine

Tipo de trabajo:Revisión

Extracto: The D/S ratio is a practical bedside scoring system in the PED and had good discriminative ability in predicting the progression of septic shock and in-hospital mortality in PED patients. Further validation is essential in other settings.

Claves:Children, Emergency department setting, Hemodynamics, Mortality, Predictors, Progression, Sepsis, Septic shock, Shock

Cita:BMC Emerg Med 2024 May 1; 24 (1) : 78.

Autor/es:Mu, Chun-Ting (a)
Lin, Ying-Jui (b)

institución:(a) Chang Gung Memorial Hospital, Chang Gung University, Taoyuan, Taiwan.
(b) College of Medicine, Chang Gung University, Taoyuan, Taiwan.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1186/s12873-024-00995-y

Endocrinology and metabolism (Seoul, Korea)

Selección SIIC: 9 Mayo, 2024

Endocrinology and metabolism (Seoul, Korea)

Bone Loss after Solid Organ Transplantation

Bone Loss after Solid Organ Transplantation

Fuente:Endocrinology and Metabolism (seoul, Korea)

Tipo de trabajo:Revisión

Extracto: This detailed review serves as an essential resource for those involved in the complex multidisciplinary care of transplant recipients.

Claves:Bone loss, Bone mineral density, Fractures, Osteoporosis, Transplantation

Cita:Endocrinol Metab (Seoul) 2024 Apr; 39 (2) : 267-282.

Autor/es:Kim, Kyoung Jin (a)
Ha, Jeonghoon (b)

institución:(a) Division of Endocrinology and Metabolism, Department of Internal Medicine, Korea University College of Medicine, Seoul, Korea.
(b) Division of Endocrinology and Metabolism, Department of Internal Medicine, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea.

Conflicto:CONFLICTS OF INTEREST No potential conflict of interest relevant to this article was reported.

Formato:Informe impreso

Idioma:Inglés

País de fuente:Corea del Sur

Sitio web:http://dx.doi.org/10.3803/EnM.2024.1939

Laryngo- rhino- otologie

Selección SIIC: 9 Mayo, 2024

Laryngo- rhino- otologie

[Interdisciplinary Management of Orbital Diseases].

[Interdisciplinary Management of Orbital Diseases].

Fuente:Laryngo- Rhino- Otologie

Extracto: The authors tried to highlight the relevant facts despite the shortness of the text.

Cita:Laryngorhinootologie 2024 May; 103 (S 01) : S43-S99.

Autor/es:Eckstein, A (a)
Welkoborsky, H-J (b)

institución:Eckstein, A (a)
Welkoborsky, H-J (b)

Conflicto:A. Eckstein erklärt: Vortragshonorare: Sanofi, Amgen,Sling. Mitarbeit an klinischen Studien: Amgen, Immunovant, Novartis.H.-J. Welboborsky war 2021-2022 Präsident der Deutschen Gesellschaft für Hals-Nasen-Ohrenheilkunde, Kopf- und Halschirurgie.

Formato:Informe impreso

Idioma:ger

País de fuente:Alemania

Sitio web:http://dx.doi.org/10.1055/a-2216-8879

Medicine

Selección SIIC: 9 Mayo, 2024

Medicine

Nongestational ovarian choriocarcinoma with bilateral teratoma

Nongestational ovarian choriocarcinoma with bilateral teratoma

Fuente:Medicine

Tipo de trabajo:Revisión

Extracto: NGCO should be considered if a female patient exhibits irregular vaginal bleeding and masses in the adnexal area. The present case and our literature review also highlighted that fertility-sparing surgery and multidrug chemotherapy are effective methods for treating NGCO.

Cita:Medicine (Baltimore) 2024 May 3; 103 (18) : e36996.

Autor/es:Ao, Xue (a)
Hu, Sha (b)

institución:(a) Department of Obstetrics and Gynecology, West China Second University Hospital, Sichuan University, Chengdu, China.
(b) Key Laboratory of Birth Defects and Related Diseases of Women and Children (Sichuan University), Ministry of Education, Chengdu, China.

Conflicto:The authors have no funding and conflicts of interest to disclose.

Formato:Informe impreso

Idioma:Inglés

País de fuente:EE.UU.

Sitio web:http://dx.doi.org/10.1097/MD.0000000000036996

Briefings in bioinformatics

Selección SIIC: 9 Mayo, 2024

Briefings in bioinformatics

AI identifies potent inducers of breast cancer stem cell differentiation based on adversarial learning from gene expression data.

AI identifies potent inducers of breast cancer stem cell differentiation based on adversarial learning from gene expression data.

Fuente:Briefings in Bioinformatics

Extracto: In particular, the efficacy of triptolide, OTS-167, quinacrine, granisetron and A-443654 offer a potential avenue for targeted therapies against breast CSCs.

Claves:artificial intelligence, breast cancer, cancer stem cells, domain adaptation, drug repurposing, transcriptomics

Cita:Brief Bioinform 2024 Mar 27; 25 (3)

Autor/es:Li, Zhongxiao (a)
Napolitano, Antonella (b)

institución:(a) Computer Science Program, Computer, Electrical and Mathematical Sciences and Engineering Division, King Abdullah University of Science and Technology (KAUST), Thuwal, 23955, Saudi Arabia.
(b) Computational Bioscience Research Center, King Abdullah University of Science and Technology, Thuwal, 23955, Saudi Arabia.

Formato:Informe impreso

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1093/bib/bbae207

International wound journal
Selección SIIC: 25 Abril, 2024
International wound journal

Prevalence of multidrug-resistant bacterial infections in diabetic foot ulcers

Prevalence of multidrug-resistant bacterial infections in diabetic foot ulcers

Fuente:International Wound Journal

Tipo de trabajo:Metanálisis

Extracto: Our study also indicated that peripheral vascular disease, peripheral neuropathy, nephropathy, osteomyelitis, Wagner's grade, previous hospitalization, and previous use of antibacterial drugs were associated with MDR bacterial infections in patients with DFUs.

Claves:MDR bacteria, diabetic foot ulcers, prevalence, risk factors

Cita:Int Wound J 2024 Apr; 21 (4) : e14864.

Autor/es:Yang, Shaoling (a)
Hu, Liye (b)

institución:(a) Department of Endocrinology, The Bethune International Peace Hospital, Shijiazhuang, China.
(b) Department of Endocrinology, The Bethune International Peace Hospital, Shijiazhuang, China.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe impreso

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1111/iwj.14864

PloS one
Selección SIIC: 25 Abril, 2024
PloS one

Factors associated with venous collaterals in patients with cerebral venous thrombosis.

Factors associated with venous collaterals in patients with cerebral venous thrombosis.

Fuente:Plos One

Tipo de trabajo:Estudio de cohortes

Extracto: In this cohort, the prevalence of venous collaterals was 25.3%. Occlusion in the superior sagittal sinus and hormonal exposure were independently associated with venous collaterals in patients with cerebral venous thrombosis.

Cita:PLoS One 2024; 19 (4) : e0302162.

Autor/es:Petchprom, Phirat (a)
Sanghan, Nuttha (b)

institución:(a) Division of Neurology, Department of Internal Medicine, Faculty of Medicine, Prince of Songkla University, Hatyai, Songkhla, Thailand.
(b) Division of Neuroradiology, Department of Radiology, Faculty of Medicine, Prince of Songkla University, Hatyai, Songkhla, Thailand.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:EE.UU.

Sitio web:http://dx.doi.org/10.1371/journal.pone.0302162

Selección SIIC: 25 Abril, 2024

The influence of diagnostic subgroups, patient- and hospital characteristics for the validity of cardiovascular diagnoses-Data from a Norwegian hospital trust.

The influence of diagnostic subgroups, patient- and hospital characteristics for the validity of cardiovascular diagnoses-Data from a Norwegian hospital trust.

Fuente:Plos One

Extracto: The diagnoses of acute myocardial infarction and stroke had excellent validity when placed during hospital stays. Similarly, heart failure diagnoses had excellent validity when echocardiography was performed before placing the diagnosis, while overall the diagnoses of heart failure and transient ischemic attack were less valid. In conclusion, the results indicate that cardiovascular diagnoses based on objective findings such as acute myocardial infarction and stroke have excellent validity and may be used as endpoints in clinical epidemiological studies with less rigid validation.

Cita:PLoS One 2024; 19 (4) : e0302181.

Autor/es:Rye, Cathrine Sæthern (a)
Ofstad, Anne Pernille (b)

institución:(a) Department of Medicine, Namsos Hospital, Nord-Trøndelag Hospital Trust, Namsos, Norway.
(b) Clinic of Cardiology, St. Olavs University Hospital, Trondheim, Norway.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:EE.UU.

Sitio web:http://dx.doi.org/10.1371/journal.pone.0302181

BMJ open
Selección SIIC: 25 Abril, 2024
BMJ open

Cardiovascular safety of evogliptin dual and triple therapy in patients with type 2 diabetes

Cardiovascular safety of evogliptin dual and triple therapy in patients with type 2 diabetes

Fuente:Bmj Open

Tipo de trabajo:Estudio de cohortes

Extracto: These findings suggest that dual or triple therapies of evogliptin for the management of type 2 diabetes in routine clinical practice present no cardiovascular harms, but could alternatively offer cardiovascular benefits in this patient population.

Claves:CARDIOLOGY, CLINICAL PHARMACOLOGY, Diabetes & endocrinology

Cita:BMJ Open 2024 Apr 15; 14 (4) : e077084.

Autor/es:Park, Sohee (a)
Jeong, Han Eol (b)

institución:(a) School of Pharmacy, Sungkyunkwan University, Suwon, South Korea.
(b) Research Department of Practice and Policy, School of Pharmacy, University College London, London, UK.

Conflicto:Competing interests: HEJ and I-SO report the receipt of research funding from the National Research Foundation of South Korea, outside the submitted work. J-YS reports the receipt of research funding from the Ministry of Food and Drug Safety, Ministry of Health and Welfare, National Research Foundation and Government-wide R&D Fund for Infectious Disease Research of South Korea, as well as... masnoticias.gif

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1136/bmjopen-2023-077084

Aging clinical and experimental research
Selección SIIC: 25 Abril, 2024
Aging clinical and experimental research

Long-term trajectories of peak expiratory flow rate in older men and women show linear decline mainly determined by baseline levels.

Long-term trajectories of peak expiratory flow rate in older men and women show linear decline mainly determined by baseline levels.

Fuente:Aging Clinical and Experimental Research

Tipo de trabajo:Estudio de cohortes

Extracto: Trajectories in both men and women differ mainly in baseline level of PEFR and not in rate of decline over time. Therefore, one PEFR measurement might be sufficient to give an indication of the trajectory that an older adult is likely to follow.

Claves:Ageing, Community-dwelling, Peak expiratory flow rate, Trajectories

Cita:Aging Clin Exp Res 2024 Apr 16; 36 (1) : 93.

Autor/es:van Schoor, Natasja M (a)
de Jongh, Renate T (b)

institución:(a) Epidemiology and Data Science, Amsterdam UMC Location Vrije Universiteit Amsterdam, De Boelelaan 1117, Amsterdam, The Netherlands. nm.vanschoor@amsterdamumc.nl.
(b) Aging & Later Life, Amsterdam Public Health Research Institute, De Boelelaan 1117, Amsterdam, The Netherlands. nm.vanschoor@amsterdamumc.nl.

Conflicto:The authors declare that they do not have competing interests.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Alemania

Sitio web:http://dx.doi.org/10.1007/s40520-024-02735-5

Scientific reports
Selección SIIC: 25 Abril, 2024
Scientific reports

Comprehensive geriatric assessment of older patients with renal disease: a cross-sectional survey.

Comprehensive geriatric assessment of older patients with renal disease: a cross-sectional survey.

Fuente:Scientific Reports

Extracto: Regression analysis revealed that the scores of activities of daily living (P = 0.024), nutritional status (P = 0.000), total social support (P = 0.014), and objective support (P = 0.000) decreased with a decline in renal function.

Cita:Sci Rep 2024 Apr 16; 14 (1) : 8758.

Autor/es:Chen, Xiaoyu (a)
Hu, Yingchun (b)

institución:(a) Department of Nephropathy and Rheumatology Immunology, Jiulongpo People's Hospital, Chongqing, China.
(b) Department of Cardiovascular, Nanfang Hospital, Southern Medical University, Guangzhou, China. yingchunh2013@163.com.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1038/s41598-024-59370-3

BMC musculoskeletal disorders
Selección SIIC: 25 Abril, 2024
BMC musculoskeletal disorders

Percutaneous kyphoplasty through unilateral puncture on the convex side for the treatment of painful osteoporotic vertebral compression fracture with scoliosis.

Percutaneous kyphoplasty through unilateral puncture on the convex side for the treatment of painful osteoporotic vertebral compression fracture with scoliosis.

Fuente:Bmc Musculoskeletal Disorders

Extracto: Combining with the proper assessment of the pre-injured life status of patients, PKP surgery using unilateral puncture on the convex side for the treatment of P-OVCF with scoliosis can achieve safe, excellent clinical, and radiographic outcomes.

Claves:Convex side, Painful osteoporotic vertebral compression fractures, Scoliosis, percutaneous kyphoplasty, Unilateral puncture

Cita:BMC Musculoskelet Disord 2024 Apr 16; 25 (1) : 294.

Autor/es:Li, Qiuhan (a)
Wang, Song (b)

institución:(a) Department of Clinical skills center, Affiliated Hospital of Southwest Medical University, 25 Taiping Road, Luzhou, 646000, Sichuan, China.
(b) Department of Orthopedics Surgery, Affiliated Hospital of Southwest Medical University, 25 Taiping Road, Luzhou, 646000, Sichuan, China. Jasewangspine@swmu.edu.cn.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1186/s12891-024-07399-w

Arthritis research & therapy
Selección SIIC: 25 Abril, 2024
Arthritis research & therapy

Long-term effects of abatacept on atherosclerosis and arthritis in older vs. younger patients with rheumatoid arthritis: 3-year results of a prospective, multicenter, observational study.

Long-term effects of abatacept on atherosclerosis and arthritis in older vs. younger patients with rheumatoid arthritis: 3-year results of a prospective, multicenter, observational study.

Fuente:Arthritis Research & Therapy

Tipo de trabajo:Estudio abierto

Extracto: ABT may decelerate atherosclerosis progression and may be useful for patients with high risk of cardiovascular disease, such as older patients. TRIAL REGISTRATION NUMBER: UMIN000014913.

Claves:Abatacept, Atherosclerosis, Elderly, Retention rate, Rheumatoid arthritis

Cita:Arthritis Res Ther 2024 Apr 17; 26 (1) : 87.

Autor/es:Yamada, Zento (a)
Muraoka, Sei (b)

institución:(a) Division of Rheumatology, Department of Internal Medicine, Toho University School of Medicine, 6-11-1 Omori-nishi, Ota-ku, Tokyo, 143-8541, Japan.
(b) Division of Rheumatology, Department of Internal Medicine, Toho University School of Medicine, 6-11-1 Omori-nishi, Ota-ku, Tokyo, 143-8541, Japan.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1186/s13075-024-03323-8

Frontiers in endocrinology
Selección SIIC: 25 Abril, 2024
Frontiers in endocrinology

Double pituitary adenomas

Double pituitary adenomas

Fuente:Frontiers in Endocrinology

Tipo de trabajo:Revisión sistemática

Extracto: The double lesion detected by surgical exploration is independently associated with a better prognosis for DPA patients. Comprehensive intraoperative exploration are crucial measures to avoid missing causative lesions.

Claves:acromegaly, biochemical remission, cushing disease, double pituitary adenomas (DPA), prognostic analysis

Cita:Front Endocrinol (Lausanne) 2024; 15 : 1373869.

Autor/es:Zhang, Yi (a)
Gong, Xinyue (b)

institución:(a) Department of Neurosurgery, Peking Union Medical College Hospital, Chinese Academy of Medical Science and Peking Union Medical College, Beijing, China.
(b) Eight-Year Program of Clinical Medicine, Peking Union Medical College, Chinese Academy of Medical Science & Peking Union Medical College, Beijing, China.

Conflicto:The authors declare the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3389/fendo.2024.1373869

Selección SIIC: 25 Abril, 2024

Clinical phenotype of a Kallmann syndrome patient with IL17RD and CPEB4 variants.

Clinical phenotype of a Kallmann syndrome patient with IL17RD and CPEB4 variants.

Fuente:Frontiers in Endocrinology

Extracto: Bioinformatics analysis shows that the IL17RD protein undergoing Gly701Ser mutation and is speculated to be phosphorylated and modified, thereby disrupting fibroblast growth factor signaling. This study also suggested that the CPEB4 might play a crucial role in the key signaling process affecting olfactory bulb morphogenesis. Overall, the findings of this study broaden the gene expression profile of KS-related pathogenic genes. This offers a new avenue for exploring the pathogenic mechanism of KS and provides valuable insights for precise clinical diagnosis and treatment strategies for this condition.

Claves:CPEB4, IL17RD, Kallmann syndrome, delayed pubertal development, gene variant

Cita:Front Endocrinol (Lausanne) 2024; 15 : 1343977.

Autor/es:Zhang, Jianmei (a)
Yang, Suhong (b)

institución:(a) Department of Pediatric Endocrinology and Genetics, Hangzhou Children's Hospital, Hangzhou, Zhejiang, China.
(b) Department of Pediatric Endocrinology and Genetics, Hangzhou Children's Hospital, Hangzhou, Zhejiang, China.

Conflicto:The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3389/fendo.2024.1343977

Selección SIIC: 25 Abril, 2024

Anastrozole monotherapy further improves near-adult height after the initial combined treatment with leuprorelin and anastrozole in early-maturing girls with compromised growth prediction: results from the second phase of the GAIL study.

Anastrozole monotherapy further improves near-adult height after the initial combined treatment with leuprorelin and anastrozole in early-maturing girls with compromised growth prediction: results from the second phase of the GAIL study.

Fuente:Frontiers in Endocrinology

Extracto: In early-maturing girls with compromised growth potential, the combined treatment with leuprorelin and anastrozole for 2 years or until the age of 11 years resulted in a total gain in height of +9.7 cm when continuing anastrozole monotherapy until the attainment of NAH, as opposed to +7.4 cm if they do not continue with the anastrozole monotherapy and +3.6 cm when treated with leuprorelin alone. Thus, the combined intervention ends at the shortest distance from the target height if continued with anastrozole monotherapy until BA 14 years.

Claves:GAIL study, LHRH analogue, adult height, anastrozole, aromatase inhibitors, early puberty, girls, precocious puberty

Cita:Front Endocrinol (Lausanne) 2024; 15 : 1366970.

Autor/es:Papadimitriou, Dimitrios T (a)
Dermitzaki, Eleni (b)

institución:(a) Department of Pediatrics, Faculty of Medicine, University of Thessaly, Larisa, Greece.
(b) Aretaieion University Hospital, National and Kapodistrian University of Athens, Athens, Greece.

Conflicto:The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. The author(s) declared that they were an editorial board member of Frontiers, at the time of submission. This had no impact on the peer review process and the final decision.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3389/fendo.2024.1366970

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