Validity and reliability of the Foot Care Scale for Older Diabetics in Turkish society.

Fuente:Wound Management & Prevention

Extracto: Both versions of the scale were found to be valid and reliable for Turkish society with regard to psychometric properties.

Cita:Wound Manag Prev 2024 Mar; 70 (1)

Autor/es:Toygar, İsmail (a)
Feyizoğlu, Güneş (b)

institución:(a) Fethiye Faculty of Health Sciences, Muğla Sıtkı Koçman University, Muğla, Turkey.
(b) Endocrinology and Metabolic Disorders Department, Göztepe Prof. Dr. Süleyman Yalçın City Hospital, İstanbul, Turkey.

Formato:Informe impreso

Idioma:Inglés

País de fuente:EE.UU.

Sitio web:http://dx.doi.org/10.25270/wmp.23022

Successful Superficial Blood Sampling to Localize a Fibroblast Growth Factor-23-Producing Tumor.

Fuente:The American Journal of Case Reports

Extracto: Octreotide scintigraphy, FDG-positron emission tomography, and systemic venous sampling are the standard methods for localizing functional endocrine tumors. However, the limited availability and invasive nature of these examinations hinder effective treatment. Here, we highlight the importance of peripheral superficial blood sampling as an alternative to conventional systemic methods for confirming the presence of FGF-23-producing tumors. Clinicians should consider TIO as a potential cause of acquired hypophosphatemic osteomalacia. Furthermore, peripheral superficial vein blood sampling may be useful for confirming the localization of FGF-23-producing tumors.

Cita:Am J Case Rep 2024 Apr 13; 25 : e943152.

Autor/es:Rikitake, Junjiro (a)
Ashida, Kenji (b)

institución:(a) Division of Endocrinology and Metabolism, Department of Internal Medicine, Kurume University School of Medicine, Kurume, Fukuoka, Japan.
(b) Division of Endocrinology and Metabolism, Department of Internal Medicine, Kurume University School of Medicine, Kurume, Fukuoka, Japan.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:EE.UU.

Sitio web:http://dx.doi.org/10.12659/AJCR.943152

Impact of dehydroepiandrosterone sulfate and free androgen index on pregnancy and neonatal outcomes in PCOS patients.

Fuente:Reproductive Biology and Endocrinology Rb&e

Tipo de trabajo:Estudio de cohortes

Extracto: In conclusion, PCOS patients with biochemical hyperandrogenism show unsatisfactory clinical PR and CLBR when undergoing assisted reproductive technology (ART). This may be attributed to the influence of both adrenal-derived DHEAS and ovarian-derived FAI on the unfavorable pregnancy outcomes.

Claves:Androgens, Cumulative live birth rates (CLBR), Cumulative pregnancy rates (CPR), Dehydroepiandrosterone sulfate (DHEAS), Free androgen index (FAI), Polycystic ovary syndrome (PCOS)

Cita:Reprod Biol Endocrinol 2024 Apr 16; 22 (1) : 43.

Autor/es:Zhao, Wen (a)
Li, Zeting (b)

institución:(a) Reproductive Medicine Center, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, Guangdong, China.
(b) Key Laboratory of Reproductive Medicine of Guangdong Province, Guangzhou, People's Republic of China.

Conflicto:The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1186/s12958-024-01212-y

Adherence to the Mediterranean diet can beneficially affect the gut microbiota composition

Fuente:Bmc Medical Genomics

Tipo de trabajo:Revisión sistemática

Extracto: Adherence to the MD is associated with significant beneficial changes in the gut microbiota diversity, composition, and functions and major clinical improvements in most populations.

Claves:Dietary intervention, Gut microbiota, Mediterranean diet

Cita:BMC Med Genomics 2024 Apr 17; 17 (1) : 91.

Autor/es:Khavandegar, Armin (a)
Heidarzadeh, Ali (b)

institución:(a) Non-Communicable Disease Research Center, Alborz University of Medical Sciences, Karaj, Iran.
(b) Sina Trauma and Surgery Research Center, Tehran University of Medical Sciences, Tehran, Iran.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1186/s12920-024-01861-3

External Validation of the Risk Assessment Model of Venous Thromboembolism in Multicenter Internal Medicine Inpatients.

Fuente:Clinical and Applied Thrombosis/hemostasis Official Journal of The International Academy of Clinical and Applied Thrombosis/hemostasis

Extracto: The SJT RAM derived from general hospitalized Chinese patients has effective and better predictive ability for internal medicine inpatients at risk of VTE.

Claves:external validation, internal medicine inpatients, multicenter, risk assessment model, venous thromboembolism

Cita:Clin Appl Thromb Hemost 2024 Jan-Dec; 30 : 10760296241247205.

Autor/es:Chen, Xiaolan (a)
Shi, Hongning (b)

institución:(a) Department of Respiratory and Critical Care Medicine, Beijing Shijitan Hospital, Capital Medical University, Beijing, China.
(b) Department of Hepatobiliary and Pancreatic Surgery, The People Hospital of Pu'er, Pu'er, China.

Conflicto:Declaration of Conflicting InterestsThe author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.

Formato:Informe impreso

Idioma:Inglés

País de fuente:EE.UU.

Sitio web:http://dx.doi.org/10.1177/10760296241247205

A novel ternary magnetic nanobiocomposite based on tragacanth-silk fibroin hydrogel for hyperthermia and biological properties.

A novel ternary magnetic nanobiocomposite based on tragacanth-silk fibroin hydrogel for hyperthermia and biological properties.

Fuente:Scientific Reports

Extracto: Finally, the hyperthermia application of the hybrid scaffold was evaluated, with a maximum SAR value of 41.2 W/g measured in the first interval.

Claves:Biological properties, Hyperthermia, Magnetic nanobiocomposite, Silk fibroin, Tragacanth hydrogel

Cita:Sci Rep 2024 Apr 8; 14 (1) : 8166.

Autor/es:Eivazzadeh-Keihan, Reza (a)
Mohammadi, Adibeh (b)

institución:(a) Catalysts and Organic Synthesis Research Laboratory, Department of Chemistry, Iran University of Science and Technology, Tehran, 16846-13114, Iran. reza.tab_chemist@yahoo.com.
(b) Catalysts and Organic Synthesis Research Laboratory, Department of Chemistry, Iran University of Science and Technology, Tehran, 16846-13114, Iran.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1038/s41598-024-58770-9

Analyzing the changing trend of corneal biomechanical properties under different influencing factors in T2DM patients.

Fuente:Scientific Reports

Extracto: In patients with T2DM, early measurement of corneal biomechanical properties to evaluate the change trend of CH and CRF values in different situations will help to identify and prevent diabetic keratopathy in a timely manner.

Claves:Corneal hysteresis, Corneal resistance factor, Diabetic keratopathy, Ocular response analyzer, T2DM

Cita:Sci Rep 2024 Apr 8; 14 (1) : 8160.

Autor/es:Tang, Juan (a)
Lin, Zhiwu (b)

institución:(a) Department of Endocrinology, Ziyang Central Hospital, Sichuan, China.
(b) Department of Cardiothoracic Surgery, Ziyang Central Hospital, Sichuan, China.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1038/s41598-024-59005-7

Comparative impact of Roux-en-Y gastric bypass, sleeve gastrectomy or diet alone on beta-cell function in insulin-treated type 2 diabetes patients.

Fuente:Scientific Reports

Extracto: Altogether, these findings indicate that bariatric surgery results in an immediate beta-cell function recovery in insulin-treated type 2 diabetes.

Cita:Sci Rep 2024 Apr 8; 14 (1) : 8211.

Autor/es:Lannoo, Matthias (a)
Simoens, Caroline (b)

institución:(a) Department of Abdominal Surgery, University Hospitals Leuven, Leuven, Belgium.
(b) Clinical and Experimental Endocrinology, Department of Chronic Diseases and Metabolism, KU Leuven, Leuven, Belgium.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1038/s41598-024-59048-w

Clinical effects of atorvastatin combined with conbercept in the treatment of patients with macular edema secondary to retinal vein occlusion and carotid plaque: study protocol for a prospective randomized controlled trial.

Clinical effects of atorvastatin combined with conbercept in the treatment of patients with macular edema secondary to retinal vein occlusion and carotid plaque: study protocol for a prospective randomized controlled trial.

Fuente:Trials

Tipo de trabajo:Estudio aleatorizado y controlado

Extracto: Registered on 12 May 2023.

Claves:Anti-vascular endothelial growth factor, Atorvastatin, Best-corrected visual acuity, Carotid plaques, Central subfield thickness, Intravitreal conbercept, Macular edema, Retinal vein occlusion

Cita:Trials 2024 Apr 8; 25 (1) : 244.

Autor/es:Yao, Bangtao (a)
Wang, Bei (b)

institución:(a) Department of Ophthalmology, Nanjing Lishui People's Hospital, Zhongda Hospital Lishui branch, Southeast University, Nanjing, Jiangsu Province, China. yaobamtao_njmu@163.com.
(b) Department of Ophthalmology, Nanjing Lishui People's Hospital, Zhongda Hospital Lishui branch, Southeast University, Nanjing, Jiangsu Province, China.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1186/s13063-024-08082-0

Anabolic-androgenic steroids are linked to depression and anxiety in male bodybuilders: the hidden psychogenic side of anabolic androgenic steroids.

Anabolic-androgenic steroids are linked to depression and anxiety in male bodybuilders: the hidden psychogenic side of anabolic androgenic steroids.

Fuente:Annals of Medicine

Extracto: The study concluded that AAS use among male bodybuilders is associated with elevated levels of depression and anxiety. Our findings suggest a potential correlation between anxiety and depression levels and the levels of creatinine, LDH, and estradiol in AAS users.

Claves:Anabolic androgenic steroids, anxiety, bodybuilder, depression

Cita:Ann Med 2024 Dec; 56 (1) : 2337717.

Autor/es:Karagun, Baris (a)
Altug, Selin (b)

institución:(a) Division of Endocrinology and Metabolism, Toros State Hospital, Mersin, Turkey.
(b) Division of Psychiatry, Toros State Hospital, Mersin, Turkey.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe impreso

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1080/07853890.2024.2337717

Association of vitamin D deficiency and subclinical diabetic peripheral neuropathy in type 2 diabetes patients.

Association of vitamin D deficiency and subclinical diabetic peripheral neuropathy in type 2 diabetes patients.

Fuente:Frontiers in Endocrinology

Extracto: Vitamin D deficiency was independently associated with subclinical DSPN, rather than other DPN subtypes.

Claves:diabetic peripheral neuropathy, distal symmetric polyneuropathy, nerve conduction study (NCS), type 2 diabetes, vitamin D

Cita:Front Endocrinol (Lausanne) 2024; 15 : 1354511.

Autor/es:Sun, Xiaoyang (a)
Yang, Xinyu (b)

institución:(a) Department of Endocrinology, Zhongshan Hospital, Fudan University, Shanghai, China.
(b) Institute of Metabolic Disease, Fudan University, Shanghai, China.

Conflicto:The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3389/fendo.2024.1354511

Relationship between autoimmune thyroid antibodies and anti-nuclear antibodies in general patients.

Fuente:Frontiers in Endocrinology

Extracto: ANA positivity and high IgG are related to Hashimoto thyroiditis but not Graves' disease, which implies distinct pathophysiological mechanisms underlying the AITDs.

Claves:Graves’ disease, Hashimoto thyroiditis, NHANES, anti-nuclear antibodies, autoimmune thyroid antibodies

Cita:Front Endocrinol (Lausanne) 2024; 15 : 1368088.

Autor/es:Ruan, Yi (a)
Heng, Xian-Pei (b)

institución:(a) Department of Endocrinology, People's Hospital Affiliated to Fujian University of Traditional Chinese Medicine, Fuzhou, China.
(b) First Clinical Medical College Fujian University of Traditional Chinese Medicine, Fuzhou, China.

Conflicto:The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3389/fendo.2024.1368088

Spatial characteristics of non-communicable diseases and their associations to social conditions in a large urban cohort in Germany-Results from the Hamburg City Health Study.

Spatial characteristics of non-communicable diseases and their associations to social conditions in a large urban cohort in Germany-Results from the Hamburg City Health Study.

Fuente:Plos One

Extracto: The study shows that regional differences in NCD prevalence persist even after adjusting for personal risk factors. This highlights the central role of both personal socio-economic status and behaviors such as alcohol and tobacco consumption. It also highlights the importance of other potential regional factors (e.g. the environment) in shaping NCD prevalence. This knowledge helps policy- and decision-makers to develop intervention strategies.

Cita:PLoS One 2024; 19 (4) : e0301475.

Autor/es:Andrees, Valerie (a)
Bei der Kellen, Ramona (b)

institución:(a) Institute for Health Service Research in Dermatology and Nursing (IVDP), University Medical Center Hamburg-Eppendorf (UKE), Hamburg, Germany.
(b) Epidemiological Study Center, Hamburg City Health Study, University Medical Center Hamburg-Eppendorf (UKE), Hamburg, Germany.

Conflicto:Jürgen Gallinat has received research funding from the German Federal Ministry of Education and Research, German Science Foundation, and speaker fees from Lundbeck, Janssen-Cilag, Lilly and Boehringer. Christina Magnussen receives study-specific funding from the German Center for Cardiovascular Research (DZHK; Promotion of women scientists programme; FKZ 81X3710112), the Deutsche Stiftung für Herzforschung, the Dr. Rolf M. Schwiete Stiftung, NDD, and... nd Loewenstein Medical unrelated to the current work. CM has received speaker fees from AstraZeneca, Novartis, Boehringer Ingelheim/Lilly, Bayer, Pfizer, Sanofi, Aventis, Apontis, Abbott outside this work. Raphael Twerenbold reports research support from the German Center for Cardiovascular Research (DZHK), the Kühne Foundation, the Joachim Herz Foundation, the Swiss National Science Foundation (Grant No P300PB_167803) and the Swiss Heart Foundation as well as speaker honoraria/consulting honoraria from Abbott, Amgen, Astra Zeneca, Psyros, Roche, Siemens, Singulex and Thermo Scientific BRAHMS, outside the submitted work. Raphael Twerenbold is co-founder and shareholder of the ART-EMIS Hamburg GmbH, which holds an international patent application on the use of a computing device to estimate the probability of myocardial infarction (International Publication Numbers WO2022043229A1, TW202219980A) Valerie Andrees, Ramona Bei der Kellen, Matthias Augustin, Volker Harth, Hanno Hoven, Simone Kühn, Anne Lautenbach, Nicole Mohr, Ines Schäfer, Benjamin Waschki, Birgit-Christiane Zyriax and Jobst Augustin declare no conflict of interest. This information does not alter our adherence to PLOS ONE policies on sharing data and materials.

Formato:Informe virtual

Idioma:Inglés

País de fuente:EE.UU.

Sitio web:http://dx.doi.org/10.1371/journal.pone.0301475

Is there any association between fluoride exposure and thyroid function modulation? A systematic review.

Fuente:Plos One

Extracto: Nonetheless, further studies with robust design and high methodological quality are required to provide evidence for policy makers and health care practitioners.

Cita:PLoS One 2024; 19 (4) : e0301911.

Autor/es:Ferreira, Maria Karolina Martins (a)
Nascimento, Priscila Cunha (b)

institución:(a) Laboratory of Functional and Structural Biology, Institute of Biological Sciences, Federal University of Pará, Belém, Pará, Brazil.
(b) Laboratory of Functional and Structural Biology, Institute of Biological Sciences, Federal University of Pará, Belém, Pará, Brazil.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:EE.UU.

Sitio web:http://dx.doi.org/10.1371/journal.pone.0301911

A new index for the outcome of focal segmental glomerulosclerosis.

A new index for the outcome of focal segmental glomerulosclerosis.

Fuente:Scientific Reports

Extracto: The proportion of segmental glomerulosclerosis provides a guiding value in the pathological diagnosis and clinical prognosis of FSGS.

Claves:FSGS, Outcome, Podocyte, Proportion, Segmental glomerulosclerosis

Cita:Sci Rep 2024 Apr 9; 14 (1) : 8278.

Autor/es:Chan, Liu (a)
Danyi, Yang (b)

institución:(a) International Medical Department, The Second Xiangya Hospital, Central South University, Changsha, Hunan, People's Republic of China.
(b) Department of Nephrology, The Second Xiangya Hospital, Central South University, No.139, Renmin Road, Changsha, 410011, Hunan, People's Republic of China. danyiyoung@csu.edu.cn.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1038/s41598-024-59007-5

A genome-wide association study provides insights into the genetic etiology of 57 essential and non-essential trace elements in humans.

A genome-wide association study provides insights into the genetic etiology of 57 essential and non-essential trace elements in humans.

Fuente:Communications Biology

Extracto: Our current understanding of trace element-associated genetic variants may help establish consequences of trace elements on human health.

Cita:Commun Biol 2024 Apr 9; 7 (1) : 432.

Autor/es:Moksnes, Marta R (a)
Hansen, Ailin F (b)

institución:(a) HUNT Center for Molecular and Clinical Epidemiology, Department of Public Health and Nursing, NTNU-Norwegian University of Science and Technology, Trondheim, Norway. marta.r.moksnes@ntnu.no.
(b) HUNT Center for Molecular and Clinical Epidemiology, Department of Public Health and Nursing, NTNU-Norwegian University of Science and Technology, Trondheim, Norway.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1038/s42003-024-06101-z

Utilize multi-metabolic parameters as determinants for prediction of skeletal muscle mass quality in elderly type2 diabetic Chinese patients.

Utilize multi-metabolic parameters as determinants for prediction of skeletal muscle mass quality in elderly type2 diabetic Chinese patients.

Fuente:Bmc Geriatrics

Extracto: In this cross-sectional study, BMI, Female, and PPCP associated with T2DM were protective factors for low muscle mass. BF was associated with T2DM and risk factor for low muscle mass.

Claves:BMI, Body fat, C-peptide, Gender, Glycemic metabolism, Muscle mass, T2DM

Cita:BMC Geriatr 2024 Apr 9; 24 (1) : 325.

Autor/es:Chen, Huiling (a)
Lou, Jingjing (b)

institución:(a) Department of Endocrinology, Shanghai Pudong Hospital, Fudan University Pudong Medical Center, 2800 Gongwei Road, Pudong, Shanghai, 201399, China.
(b) Fudan University, Shanghai, China.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1186/s12877-024-04827-3

An ecological resilience model for adolescents with type 1 diabetes: a cross-sectional study.

An ecological resilience model for adolescents with type 1 diabetes: a cross-sectional study.

Fuente:Bmc Psychiatry

Extracto: Family functioning, peer relationships, and positive coping are interrelated, which may jointly influence resilience. The findings provide a theoretical basis for developing resilience-promotion interventions for adolescents with type 1 diabetes, which may lead to health improvements during a vulnerable developmental period.

Claves:Adolescents, Diabetes type 1, Ecological determinants, Resilience

Cita:BMC Psychiatry 2024 Apr 9; 24 (1) : 263.

Autor/es:Luo, Dan (a)
Cai, Xue (b)

institución:(a) School of Nursing, Nanjing University of Chinese Medicine, Jiangsu, China. luodan@njucm.edu.cn.
(b) Department of Respiratory, Department of Nursing, School of Medicine, Zhongda Hospital, Southeast University, Jiangsu, China.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1186/s12888-024-05634-1

Longitudinal study of the impact of the COVID-19 pandemic on diet and physical activity among Latinos of Mexican ancestry.

Longitudinal study of the impact of the COVID-19 pandemic on diet and physical activity among Latinos of Mexican ancestry.

Fuente:Journal of Translational Medicine

Extracto: Societal disruption during the COVID-19 pandemic had minimal effects on adverse health-related behaviors, cardiometabolic risk, or changes in glycemic control in a Latino community with diabetes and healthcare disparities in the Southwest US.

Claves:COVID-19, Diet, Food security, Physical activity, Type 2 diabetes

Cita:J Transl Med 2024 Apr 9; 22 (1) : 342.

Autor/es:Muscogiuri, Giovanna (a)
Kohler, Lindsay (b)

institución:(a) Dipartimento di Medicina Clinica e Chirurgia, Unità di Endocrinologia, Diabetologia e Andrologia, Università degli Studi Di Napoli Federico II, Naples, Italy.
(b) Cattedra Unesco "Educazione alla salute e allo sviluppo sostenibile", University Federico II, Naples, Italy.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1186/s12967-024-05007-y

Association of adrenal steroids with metabolomic profiles in patients with primary and endocrine hypertension.

Association of adrenal steroids with metabolomic profiles in patients with primary and endocrine hypertension.

Fuente:Frontiers in Endocrinology

Extracto: In CS, cortisol, alongside other non-defining adrenal hormones, contributes to these differences, suggesting that metabolic disorders and cardiovascular morbidity in these conditions could also be affected by various adrenal steroids.

Claves:Cushing’s syndrome, adrenal steroids, endocrine hypertension, metabolomics, pheochromocytoma, primary aldosteronism, primary hypertension

Cita:Front Endocrinol (Lausanne) 2024; 15 : 1370525.

Autor/es:Knuchel, Robin (a)
Erlic, Zoran (b)

institución:(a) Klinik für Endokrinologie, Diabetologie und Klinische Ernährung, UniversitätsSpital Zürich (USZ) und Universität Zürich (UZH), Zurich, Switzerland.
(b) Klinik für Endokrinologie, Diabetologie und Klinische Ernährung, UniversitätsSpital Zürich (USZ) und Universität Zürich (UZH), Zurich, Switzerland.

Conflicto:The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3389/fendo.2024.1370525