Disease related changes in ATAC-seq of iPSC-derived motor neuron lines from ALS patients and controls.

Disease related changes in ATAC-seq of iPSC-derived motor neuron lines from ALS patients and controls.

Fuente:Nature Communications

Extracto: These results suggest that iPSC-derived motor neurons recapitulate important disease-relevant epigenomic changes.

Cita:Nat Commun 2024 May 2; 15 (1) : 3606.

Autor/es:Tsitkov, Stanislav (a)
Valentine, Kelsey (b)

institución:(a) Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA.
(b) Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1038/s41467-024-47758-8

Response of treatment-naive brain metastases to stereotactic radiosurgery.

Fuente:Nature Communications

Extracto: These studies will help establish multi-disciplinary treatment guidelines that improve local control while minimizing radiation necrosis during treatment of brain metastasis ≤3 cm.

Cita:Nat Commun 2024 May 2; 15 (1) : 3728.

Autor/es:Ene, Chibawanye I (a)
Abi Faraj, Christina (b)

institución:(a) Department of Neurosurgery, The University of Texas M D Anderson Cancer Center, Houston, TX, USA. cene@mdanderson.org.
(b) Department of Neurosurgery, The University of Texas M D Anderson Cancer Center, Houston, TX, USA.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1038/s41467-024-47998-8

Predictors of social risk for post-ischemic stroke reintegration.

Predictors of social risk for post-ischemic stroke reintegration.

Fuente:Scientific Reports

Extracto: Due to the complex and multifactorial nature of social risk, factors in combination, including social support and economic status, drive social risk for individuals.

Claves:Machine learning, Prediction model, Rehabilitation, Reintegration, SHAP analysis, Social risk, Socioeconomic support, Stroke

Cita:Sci Rep 2024 May 2; 14 (1) : 10110.

Autor/es:Cisek, Katryna K (a)
Nguyen, Thi Nguyet Que (b)

institución:(a) AIDHM, Artificial Intelligence in Digital Health and Medicine, Technological University Dublin, Dublin, Ireland. katryna.cisek@tudublin.ie.
(b) RESQ+, Comprehensive solutions of healthcare improvement based on the global Registry of Stroke Care Quality, Horizon Europe Project, Brno, Czech Republic. katryna.cisek@tudublin.ie.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1038/s41598-024-60507-7

Subjects with carotid webs demonstrate pro-thrombotic hemodynamics compared to subjects with carotid atherosclerosis.

Fuente:Scientific Reports

Extracto: These abnormal hemodynamic metrics in patients with CaW are associated with clot formation and vascular dysfunction and suggest that hemodynamic assessment may be a tool to assess stroke risk in these patients.

Cita:Sci Rep 2024 May 2; 14 (1) : 10092.

Autor/es:El Sayed, Retta (a)
Lucas, Carissa J (b)

institución:(a) Department of Biomedical Engineering, Georgia Institute of Technology, Emory University, 1364 Clifton Rd, Atlanta, GA, 30322, USA.
(b) Department of Radiology and Imaging Sciences, Emory University, Atlanta, GA, USA.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1038/s41598-024-60666-7

Reduced processing of afforded actions while observing mental content as ongoing mental phenomena.

Fuente:Scientific Reports

Extracto: Our results indicate that OM styles of meditation may help in mentally decoupling otherwise automatic cognitive processing of mental actions by affording objects.

Cita:Sci Rep 2024 May 2; 14 (1) : 10130.

Autor/es:Katyal, Sucharit (a)
Abdoun, Oussama (b)

institución:(a) EDUWELL Team, Lyon Neuroscience Research Centre, INSERM U1028, CNRS UMR5292, Lyon 1 University, Lyon, France. ska@psy.ku.dk.
(b) Department of Psychology, University of Copenhagen, Copenhagen, Denmark. ska@psy.ku.dk.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1038/s41598-024-60934-6

Artificial intelligence for volumetric measurement of cerebral white matter hyperintensities on thick-slice fluid-attenuated inversion recovery (FLAIR) magnetic resonance images from multiple centers.

Fuente:Scientific Reports

Extracto: Despite some limitations, this model may be applicable in clinical practice.

Claves:Artificial intelligence, Fluid-attenuated inversion recovery, Magnetic resonance imaging, White matter hyperintensity

Cita:Sci Rep 2024 May 2; 14 (1) : 10104.

Autor/es:Kuwabara, Masashi (a)
Ikawa, Fusao (b)

institución:(a) Department of Neurosurgery, Graduate School of Biomedical and Health Sciences, Hiroshima University, 1-2-3 Kasumi, Minami-Ku, Hiroshima, Hiroshima, 734-8551, Japan.
(b) Department of Neurosurgery, Graduate School of Biomedical and Health Sciences, Hiroshima University, 1-2-3 Kasumi, Minami-Ku, Hiroshima, Hiroshima, 734-8551, Japan. fikawa-nsu@umin.ac.jp.

Conflicto:Shinji Nakazawa, Ryo Sato, and Shiyuki Maeyama are employees of LPIXEL Inc. Yuki Shimahara owns stock in the company. Taiki Kaneko is currently an employee of Aile Home Clinic, Niigata, Japan. Masashi Kuwabara, Fusao Ikawa, Saori Koshino, Daizo Ishii, Hiroshi Kondo, Takeshi Hara, Yuyo Maeda, and Nobutaka Horie declare no potential conflict of interest.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1038/s41598-024-60789-x

Muscle mass as a modifier of stress response in acute ischemic stroke patients.

Fuente:Scientific Reports

Extracto: Our findings highlight the importance of muscle mass as a novel factor related to the level of post-stroke stress response.

Cita:Sci Rep 2024 May 2; 14 (1) : 10088.

Autor/es:Arsava, Ethem Murat (a)
Gungor, Levent (b)

institución:(a) Department of Neurology, Faculty of Medicine, Hacettepe University, 06230, Altindag, Ankara, Turkey. arsavaem@hotmail.com.
(b) Department of Neurology, Ondokuz Mayis University, Samsun, Turkey.

Conflicto:EMA: received honoraria from Sanofi, Abbott, and Nutricia. He served on the advisory boards of Sanofi and Nutricia. LG: received honoraria from Sanofi, Amgen, Nutricia, Nestle, Abbott, and Fresenius-Kabi. He served on the national advisory boards of Nutricia and Fresenius-Kabi. MAT: received honoraria from Sanofi and Abbott. He served on the advisory boards for Abbott and Sanofi. The remaining authors... declare no competing interests.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1038/s41598-024-60829-6

Human intraparietal sulcal morphology relates to individual differences in language and memory performance.

Human intraparietal sulcal morphology relates to individual differences in language and memory performance.

Fuente:Communications Biology

Extracto: The results highlight a promising area of investigation on the relationship between cognitive performance, sulco-gyral pattern and white matter bundles.

Cita:Commun Biol 2024 May 2; 7 (1) : 520.

Autor/es:Santacroce, Federica (a)
Cachia, Arnaud (b)

institución:(a) Department of Neuroscience, Imaging and Clinical Sciences, and ITAB, Gabriele d'Annunzio University, Via Luigi Polacchi 11, 66100, Chieti, Italy. federica.santacroce@unich.it.
(b) Université Paris Cité, Laboratoire de Psychologie du développement et de l'Education de l'Enfant (LaPsyDÉ), CNRS UMR 8240, Paris, France.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1038/s42003-024-06175-9

Exploration of neuroanatomical characteristics to differentiate prodromal Alzheimer's disease from cognitively unimpaired amyloid-positive individuals.

Exploration of neuroanatomical characteristics to differentiate prodromal Alzheimer's disease from cognitively unimpaired amyloid-positive individuals.

Fuente:Scientific Reports

Extracto: The reduced volume in the superior parietal cortex may play a significant role in the progression to prodromal AD through its interaction with amyloid deposition in that region.

Cita:Sci Rep 2024 May 2; 14 (1) : 10083.

Autor/es:Kim, Hak Hyeon (a)
Kwon, Min Jeong (b)

institución:(a) Department of Neuropsychiatry, Seoul National University Bundang Hospital, 82 Gumi-ro 173 Beon-gil, Bundang-gu, Seongnam-si, Gyeonggi-do, 13620, South Korea.
(b) Department of Psychiatry, College of Medicine, Seoul National University, Seoul, South Korea.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1038/s41598-024-60843-8

Prefrontal tDCS modulates risk-taking in male violent offenders.

Fuente:Scientific Reports

Extracto: These results suggest baseline dependent effects of tDCS and pave the way for treatment options of disadvantageous decision-making behavior in this population.

Claves:Prefrontal cortex, Risk-taking, Violent offenders, fMRI, tDCS

Cita:Sci Rep 2024 May 2; 14 (1) : 10087.

Autor/es:Kuhn, Leandra (a)
Choy, Olivia (b)

institución:(a) Department of Psychiatry, Psychotherapy and Psychosomatics, Faculty of Medicine, RWTH Aachen, Pauwelsstr. 30, 52074, Aachen, Germany. lkuhn@ukaachen.de.
(b) Department of Psychology, Nanyang Technological University, Singapore, Singapore.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1038/s41598-024-60795-z

Serum exosomes miR-206 and miR-549a-3p as potential biomarkers of traumatic brain injury.

Fuente:Scientific Reports

Extracto: In conclusion, serum exosomes miR-206 and miR-549a-3p have the potential to serve as potential biomarkers in patients with TBI.

Claves:Biomarker, Exosomes, TBI, miR-206, miR-549a-3p

Cita:Sci Rep 2024 May 2; 14 (1) : 10082.

Autor/es:Yang, Yajun (a)
Wang, Yi (b)

institución:(a) Department of Neurosurgery, The First Hospital of Shanxi Medical University, Taiyuan, China.
(b) The First School of Clinical Medicine, Shanxi Medical University, Taiyuan, China.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1038/s41598-024-60827-8

Construction of oxidative phosphorylation-related prognostic risk score model in uveal melanoma.

Construction of oxidative phosphorylation-related prognostic risk score model in uveal melanoma.

Fuente:Bmc Ophthalmology

Extracto: In sum, a prognostic risk score model based on oxidative phosphorylation-related genes in UVM was developed to enhance understanding of the disease. This prognostic risk score model may help to find potential therapeutic targets for UVM patients. CYC1 acts as an oncogene role in UVM.

Claves:LASSO regression, Oxidative phosphorylation (OXPHOS), Prognostic risk score model, Uveal melanoma (UVM)

Cita:BMC Ophthalmol 2024 May 2; 24 (1) : 204.

Autor/es:Zhan, Zhiyun (a)
Lin, Kun (b)

institución:(a) Ophthalmology Department, First Affiliated Hospital of Fujian Medical University, No. 20, Chazhong Road, Taijiang District, 350004, Fuzhou, Fujian, China.
(b) Department of Neurosurgery, Shengli Clinical Medical College of Fujian Medical University, 516 Jinrong South Road, 350001, Fuzhou, China.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1186/s12886-024-03441-6

Assessing the impact of migraine on benign paroxysmal positional vertigo symptoms and recovery.

Assessing the impact of migraine on benign paroxysmal positional vertigo symptoms and recovery.

Fuente:Bmc Neurology

Extracto: Clinicians are advised to inquire about migraine when evaluating patients with BPPV because it may lead to more intricate and severe clinical presentation. Further studies will be elaborated the genuine nature of the causal relationship between migraine and BPPV.

Claves:BPPV, Benign paroxysmal positional vertigo, Dizziness, Migraine, Vertigo

Cita:BMC Neurol 2024 May 2; 24 (1) : 148.

Autor/es:Çakır, Seda (a)
Sahin, Aysenur (b)

institución:(a) Department of Neurology, Acıbadem University School of Medicine, İçerenköy. Kayışdağı Cad. No: 32. Ataşehir, İstanbul, 34752, Turkey.
(b) Department of Neurology, Acıbadem University School of Medicine, İçerenköy. Kayışdağı Cad. No: 32. Ataşehir, İstanbul, 34752, Turkey.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1186/s12883-024-03606-2

Prevalence of Parkinson's disease among adults aged 45 years and older in China: a cross-sectional study based on the China health and retirement longitudinal study.

Prevalence of Parkinson's disease among adults aged 45 years and older in China: a cross-sectional study based on the China health and retirement longitudinal study.

Fuente:Bmc Public Health

Extracto: The prevalence of PD increased with age in the Chinese population.

Claves:Aging, Chinese mainland population, Parkinson’s disease, Prevalence

Cita:BMC Public Health 2024 May 2; 24 (1) : 1218.

Autor/es:Meng, Detao (a)
Wu, Jiayu (b)

institución:(a) Parkinson Medical Center, Beijing Rehabilitation Hospital, Capital Medical University, Shijingshan District, BadachuBejing, 100144, Xixiazhuang, China. mengdt@mail.ccmu.edu.cn.
(b) Department of Neurorehabilitation, Xiamen Humanity Rehabilitation Hospital, Fujian, China.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1186/s12889-024-18653-0

NTSM: a non-salient target segmentation model for oral mucosal diseases.

NTSM: a non-salient target segmentation model for oral mucosal diseases.

Fuente:Bmc Oral Health

Extracto: Our model has high segmentation accuracy on non-salient areas of oral mucosal diseases and can effectively reduce resource consumption.

Claves:Convolutional neural network, Depthwise separable convolution, Medical image segmentation, Non-salient target, Oral mucosal diseases

Cita:BMC Oral Health 2024 May 3; 24 (1) : 521.

Autor/es:Ju, Jianguo (a)
Zhang, Qian (b)

institución:(a) School of Information Science and Technology, Northwest University, No.1, Xuefu Road, Xi'an, 710119, Shaanxi, China.
(b) School of Information Science and Technology, Northwest University, No.1, Xuefu Road, Xi'an, 710119, Shaanxi, China.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1186/s12903-024-04193-x

Help-seeking processes related to targeted school-based mental health services

Help-seeking processes related to targeted school-based mental health services

Fuente:Bmc Public Health

Tipo de trabajo:Revisión sistemática

Extracto: The findings of this review ought to guide the delivery and development of TSMS to facilitate access and promote help-seeking behaviours. Particularly, given the evidence gaps identified in the field, future studies should prioritise investigating TSMS in low- and middle-income settings and through quantitative methodologies. REGISTRATION: The protocol for this systematic review was registered on PROSPERO (ID CRD42023406824).

Claves:Adolescent, Help-seeking, Intervention, Mental Health, School, Systematic reviews

Cita:BMC Public Health 2024 May 2; 24 (1) : 1217.

Autor/es:McPhail, Lauren (a)
Thornicroft, Graham (b)

institución:(a) Centre for Global Mental Health, Health Service and Population Research Department, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, UK. Lauren.mcphail@kcl.ac.uk.
(b) Centre for Global Mental Health and Centre for Implementation Science, Health Service and Population Research Department, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, UK.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1186/s12889-024-18714-4

Dietary factors and Alzheimer's disease risk: a Mendelian randomization study.

Dietary factors and Alzheimer's disease risk: a Mendelian randomization study.

Fuente:European Journal of Medical Research

Extracto: In this MR analysis, our finding did not provide evidence to support the causal genetic relationships between dietary habits and AD risk.

Claves:Alzheimer’s disease, Dietary habits, Genome-wide association study, Mendelian randomization

Cita:Eur J Med Res 2024 May 2; 29 (1) : 261.

Autor/es:Meng, Qi (a)
Chen, Chen (b)

institución:(a) Department of Neurology, Henan Provincial People's Hospital, Zhengzhou University People's Hospital, 7 Weiwu Street, Zhengzhou, 450000, China. mengqhnsy@163.com.
(b) Department of Neurology, Henan Provincial People's Hospital, Zhengzhou University People's Hospital, 7 Weiwu Street, Zhengzhou, 450000, China.

Conflicto:The authors declare no interest.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1186/s40001-024-01821-8

Detecting language network alterations in mild cognitive impairment using task-based fMRI and resting-state fMRI: A comparative study.

Detecting language network alterations in mild cognitive impairment using task-based fMRI and resting-state fMRI: A comparative study.

Fuente:Brain and Behavior

Extracto: Task-based fMRI and ICA are more sophisticated and reliable tools in evaluation cognitive impairments in language processing. Our findings support the neural mechanisms of the cognitive impairments in MCI.

Claves:independent component analysis, language network, mild cognitive impairment, resting‐state fMRI, task‐based fMRIi

Cita:Brain Behav 2024 May; 14 (5) : e3518.

Autor/es:Kemik, Kerem (a)
Ada, Emel (b)

institución:(a) Department of Neuroscience, Institute of Health Sciences, Dokuz Eylül University, Izmir, Turkey.
(b) Department of Radiology, Dokuz Eylül University Medicine Faculty, Izmir, Turkey.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe impreso

Idioma:Inglés

País de fuente:EE.UU.

Sitio web:http://dx.doi.org/10.1002/brb3.3518

Investigating disparities in smoking cessation treatment for veterans with multiple sclerosis: A national analysis.

Fuente:Brain and Behavior

Extracto: VwMS received significantly less smoking cessation treatment, compared to matched controls without MS, showing a critical gap in health services as VwMS are not receiving dual NRT as the standard of care. Prescription rates were especially lower for male and Black VwMS, suggesting that under-represented demographic groups outside of the white female category, most often considered as the "traditional MS" group, could be under-treated regarding smoking cessation support. This foundational work will help inform future work to promote equitable treatment and implementation of cessation interventions for people living with MS.

Claves:Health equity, Multiple Sclerosis, Smoking cessation, Veterans

Cita:Brain Behav 2024 May; 14 (5) : e3513.

Autor/es:Polick, Carri S (a)
Dennis, Paul (b)

institución:(a) Durham VA Health Care System, Durham, North Carolina, USA.
(b) School of Nursing, Duke University, Durham, North Carolina, USA.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe impreso

Idioma:Inglés

País de fuente:EE.UU.

Sitio web:http://dx.doi.org/10.1002/brb3.3513

Psychometric properties of the Danish version of the Caregiver Burden Scale: Investigating predictors and severity of burden after stroke, spinal cord injury, or traumatic brain injury.

Psychometric properties of the Danish version of the Caregiver Burden Scale: Investigating predictors and severity of burden after stroke, spinal cord injury, or traumatic brain injury.

Fuente:Journal of Rehabilitation Medicine

Extracto: Good psychometric properties were reported, and most caregivers reported a low level of burden, and longer time as a caregiver was associated with higher burden. Consequently, the Caregiver Burden Scale is a valid measure to use when measuring burden in caregivers of stroke, spinal cord injury, and traumatic brain injury patients.

Cita:J Rehabil Med 2024 May 2; 56 : jrm34732.

Autor/es:Norup, Anne (a)
Soendergaard, Pernille Langer (b)

institución:(a) Neurorehabilitation Research & Knowledge Centre, Copenhagen University Hospital - Rigshospitalet, Copenhagen, Glostrup, Denmark; Department of Neuroscience, University of Copenhagen, Copenhagen, Denmark. anne.norup@regionh.dk.
(b) Neurorehabilitation Research & Knowledge Centre, Copenhagen University Hospital - Rigshospitalet, Copenhagen, Glostrup, Denmark; Neurorehabilitation-CPH, City of Copenhagen, Hellerup, Denmark.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suecia

Sitio web:http://dx.doi.org/10.2340/jrm.v56.34732