Calibrating Deep Learning Classifiers for Patient-Independent Electroencephalogram Seizure Forecasting.

Fuente:Sensors (basel, Switzerland)

Extracto: Although our method still requires at least one epileptic event per patient to calibrate the forecasting model, we conclude that focusing on realistic validation methods allows to more reliably compare different machine learning approaches for seizure prediction, enabling the implementation of robust and effective forecasting systems that can be used in daily healthcare practice.

Claves:cross-subject, cross-validation, domain adaptation, electroencephalography, epilepsy, machine learning, model calibration, model validation, seizure prediction, signal processing

Cita:Sensors (Basel) 2024 Apr 30; 24 (9)

Autor/es:Shafiezadeh, Sina (a)
Duma, Gian Marco (b)

institución:(a) Department of General Psychology, University of Padova, 35131 Padova, Italy.
(b) Epilepsy and Clinical Neurophysiology Unit, Scientific Institute, IRCCS E. Medea, 31015 Conegliano, Italy.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3390/s24092863

Brain Networks Modulation during Simple and Complex Gait: A "Mobile Brain/Body Imaging" Study.

Fuente:Sensors (basel, Switzerland)

Extracto: This study advances our understanding of neural dynamics during overground walking, emphasizing the multidimensional nature of gait control involving cognitive and affective networks.

Claves:affective network, cognitive network, dual task, gait, high-density electroencephalography

Cita:Sensors (Basel) 2024 Apr 30; 24 (9)

Autor/es:Bonassi, Gaia (a)
Zhao, Mingqi (b)

institución:(a) Department of Neuroscience, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health, University of Genoa, 16132 Genoa, Italy.
(b) Research Center for Motor Control and Neuroplasticity, KU Leuven, 3001 Leuven, Belgium.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3390/s24092875

Helping Blind People Grasp: Evaluating a Tactile Bracelet for Remotely Guiding Grasping Movements.

Fuente:Sensors (basel, Switzerland)

Extracto: While participants were faster with the auditory commands, they also performed well with the bracelet, encouraging future development of this system and similar systems.

Claves:assistive technology, blindness, grasping, sensory augmentation, tactile bracelet, visual impairment

Cita:Sensors (Basel) 2024 May 6; 24 (9)

Autor/es:Powell, Piper (a)
Pätzold, Florian (b)

institución:(a) Institute of Cognitive Science, University of Osnabrück, 49069 Osnabrück, Germany.
(b) Institute of Cognitive Science, University of Osnabrück, 49069 Osnabrück, Germany.

Conflicto:Author Silke M. Kärcher is the CEO of feelSpace GmbH. The remaining authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3390/s24092949

Artificial neural network identified a 20-gene panel in predicting immunotherapy response and survival benefits after anti-PD1/PD-L1 treatment in glioblastoma patients.

Fuente:Cancer Medicine

Tipo de trabajo:Estudio clínico

Extracto: The 20-gene panel developed by the ANN could be a promising biomarker for predicting immunotherapy response and prognostic benefits in ICI-treated GBM patients and may guide oncologists to accurately select potential responders for the preferential use of ICIs.

Claves:artificial neural network model, glioblastoma, immune checkpoint inhibitor, immunotherapy

Cita:Cancer Med 2024 May; 13 (9) : e7218.

Autor/es:Wang, Yaning (a)
Wang, Zihao (b)

institución:(a) Department of Neurosurgery, Center for Malignant Brain Tumors, National Glioma MDT Alliance, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking UnionMedical College, Beijing, China.
(b) Department of Neurosurgery, Center for Malignant Brain Tumors, National Glioma MDT Alliance, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking UnionMedical College, Beijing, China.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe impreso

Idioma:Inglés

País de fuente:EE.UU.

Sitio web:http://dx.doi.org/10.1002/cam4.7218

Validation and assessment of psychometric properties of the Greek Eating Behaviors Assessment for Obesity (GR-EBA-O).

Fuente:Eating and Weight Disorders Ewd

Extracto: The Greek version of the EBA-O has demonstrated sound psychometric properties and appears a reliable and user-friendly tool to identify pathological eating behaviors in obesity. LEVEL OF EVIDENCE: V, descriptive research.

Claves:Assessment, Eating behavior, Greek validation, Obesity, Psychometric properties

Cita:Eat Weight Disord 2024 May 11; 29 (1) : 36.

Autor/es:Mavrandrea, Panagiota (a)
Aloi, Matteo (b)

institución:(a) Eating Disorders Unit, 1st Department of Psychiatry, National and Kapodistrian University of Athens, Eginition Hospital, Vas Sofias 74, 11526, Athens, Greece.
(b) Department of Clinical and Experimental Medicine, University of Messina, Messina, Italy.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Alemania

Sitio web:http://dx.doi.org/10.1007/s40519-024-01664-6

Plasma biomarkers increase diagnostic confidence in patients with Alzheimer's disease or frontotemporal lobar degeneration.

Fuente:Alzheimer's Research & Therapy

Extracto: In an academic tertiary care center, plasma biomarkers supported clinicians by increasing their diagnostic confidence in most cases, despite a negligible impact on diagnosis. Future prospective studies are needed to assess the full potential of plasma biomarkers on clinical grounds.

Claves:Alzheimer’s disease, Diagnosis, Diagnostic confidence, Frontotemporal lobar degeneration, Plasma biomarkers

Cita:Alzheimers Res Ther 2024 May 11; 16 (1) : 107.

Autor/es:Altomare, Daniele (a)
Libri, Ilenia (b)

institución:(a) Department of Clinical and Experimental Sciences, Neurology Unit, University of Brescia, Brescia, Italy.
(b) Department of Clinical and Experimental Sciences, Neurology Unit, University of Brescia, Brescia, Italy.

Conflicto:Daniele Altomare received funding by the Fondation Recherche Alzheimer, and the Swiss National Science Foundation (project CRSK-3_196354/1). Nicholas J. Ashton serves as an editor of Alzheimer’s Research & Therapy.Henrik Zetterberg serves as an editor of Alzheimer’s Research & Therapy.Barbara Borroni served as a medical advisor for Alector, Denali, Wave, AviadoBio, Lilly, and UCB. The other authors have nothing to disclose.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1186/s13195-024-01474-z

Atypical skin conditions of the neck and back as a dermal manifestation of anti-HMGCR antibody-positive myopathy.

Fuente:Bmc Immunology

Extracto: HMGCR-IMNM patients frequently have atypical skin conditions of the neck and back. Skin biopsy specimens from these lesions showed the same Bcl-2-positive lymphocytic infiltrations as muscle biopsy specimens regardless of the different gross dermal findings. Thus, such atypical skin conditions may be suggestive for HMGCR-IMNM.

Claves:3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMGCR), Bcl-2, Immune-mediated necrotizing myopathy, Jessner’s lymphocytic infiltration of skin

Cita:BMC Immunol 2024 May 11; 25 (1) : 30.

Autor/es:Kurashige, Takashi (a)
Nakamura, Rie (b)

institución:(a) Department of Neurology, NHO Kure Medical Center, Chugoku Cancer Center, Kure, Japan. takashi-kurashige@hiroshima-u.ac.jp.
(b) Department of Dermatology, NHO Kure Medical Center, Chugoku Cancer Center, Kure, Japan.

Conflicto:The authors declare that they have no conflict of interest.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1186/s12865-024-00622-2

Spinal magnetic resonance imaging artifacts in lumboperitoneal shunt surgery using adjustable valve implantation on the paravertebral spinal muscles.

Fuente:The Journal of Medical Investigation Jmi

Tipo de trabajo:Revisión

Extracto: LPS surgery with adjustable valve implantation on paravertebral muscles did not cause valve-induced artifacts in the spine and spinal cord. We considered that LPS could simplify the postoperative care of these patients. J. Med. Invest. 71 : 154-157, February, 2024.

Claves:artifact, hydrocephalus, lumboperitoneal shunt, magnetic resonance imaging, programmable valve

Cita:J Med Invest 2024; 71 (1.2) : 154-157.

Autor/es:Tanaka, Tatsuya (a)
Sashida, Ryohei (b)

institución:(a) Department of Neurosurgery, International University of Health and Welfare Narita Hospital, Chiba, Japan.
(b) Department of Neurosurgery, New Yachimata General Hospital, Chiba, Japan.

Formato:Informe impreso

Idioma:Inglés

País de fuente:Japón

Sitio web:http://dx.doi.org/10.2152/jmi.71.154

Chondrosarcoma evaluation using hematein-based x-ray staining and high-resolution 3D micro-CT: a feasibility study.

Fuente:European Radiology Experimental

Extracto: Using nondestructive 3D micro-CT, the simultaneous visualization of radiological and histopathological features is feasible. RELEVANCE STATEMENT: 3D micro-CT data supports modern radiological and histopathological investigations of human bone tumor specimens. It has the potential for being an integrative part of clinical preoperative diagnostics. KEY POINTS: • Matrix calcifications are a relevant diagnostic feature of bone tumors. • Micro-CT detects all clinically diagnostic relevant features of x-ray-stained chondrosarcoma. • Micro-CT has the potential to be an integrative part of clinical diagnostics.

Claves:Bone neoplasms, Chondrosarcoma, Hematein, Staining and labeling, X-ray microtomography

Cita:Eur Radiol Exp 2024 May 13; 8 (1) : 58.

Autor/es:Gersing, Alexandra S (a)
Kimm, Melanie A (b)

institución:(a) Department of Diagnostic and Interventional Radiology, School of Medicine, Klinikum rechts der Isar, Technical University of Munich, Ismaningerstr. 22, Munich, 81675, Germany. alexandra.gersing@tum.de.
(b) Department of Neuroradiology, LMU University Hospital, LMU Munich, Munich, Germany. alexandra.gersing@tum.de.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1186/s41747-024-00454-0

Facial Asymmetry Caused by Mandibular Condylar Hyperplasia: A Two Center Study.

Fuente:The Israel Medical Association Journal Imaj

Extracto: Proportional condylectomy could be a viable treatment to both arrest the condylar overgrowth and achieve some correction of the facial asymmetry.

Cita:Isr Med Assoc J 2024 May; 26 (5) : 289-293.

Autor/es:Abboud, Waseem (a)
Shamir, Dror (b)

institución:(a) Department of Neurology, Sheba Medical Center, Tel Hashomer, Israel, Department of Oral and Maxillofacial Surgery, Bnai Zion Medical Center, Haifa, Israel, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel, Rappaport Faculty of Medicine, Technion-Israel Institute of Technology, Haifa, Israel.
(b) Department of Oral and Maxillofacial Surgery, Bnai Zion Medical Center, Haifa, Israel, Rappaport Faculty of Medicine, Technion-Israel Institute of Technology, Haifa, Israel.

Formato:Informe impreso

Idioma:Inglés

País de fuente:Israel

Sitio web:

Nitrous Oxide-induced Myeloneuropathy Due to Recreational Abuse.

Fuente:The Israel Medical Association Journal Imaj

Extracto: Enhancing awareness, prompting the use of appropriate investigations, and advocating for timely treatment are needed to overcome the risks associated with nitrous oxide misuse.

Cita:Isr Med Assoc J 2024 May; 26 (5) : 294-298.

Autor/es:Dabby, Ron (a)
Paleacu Kertesz, Diana (b)

institución:(a) Department of Neurology, Wolfson Medical Center, Holon, Israel, Faculty of Medical and Health Sciences, Tel Aviv University, Tel Aviv, Israel.
(b) Abarbanel Mental Health Center, Bat Yam, Israel.

Formato:Informe impreso

Idioma:Inglés

País de fuente:Israel

Sitio web:

Association Analysis of Essential Tremor-Associated Genetic Variants in Sporadic Late-Onset Parkinson's Disease.

Fuente:Tremor and Other Hyperkinetic Movements (new York, N.y.)

Extracto: Our results do not support the role of ET-associated genetic loci and variants in LOPD. HIGHLIGHTS: 1962 cases and 1279 controls were recruited to study the potential genetic interplay between ET-associated genetic loci/variants and sporadic LOPD.No significant association between the ET-associated SNPs and LOPD were observed.No significant burden of rare deleterious variants of ET-associated gene in LOPD risk were found.

Claves:Parkinson’s disease, SKAT-O, association analysis, essential tremor, genetic variant, rare deleterious variants

Cita:Tremor Other Hyperkinet Mov (N Y) 2024; 14 : 25.

Autor/es:Zeng, Sheng (a)
Zhou, Xun (b)

institución:(a) Department of Geriatrics, The Second Xiangya Hospital, Central South University, Changsha, Hunan 410011, China.
(b) Key Laboratory of Hunan Province in Neurodegenerative Disorders, Central South University, Changsha, Hunan, 410008, China.

Conflicto:The authors have no competing interests to declare.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.5334/tohm.885

A Novel KCNQ2 Variant in a Patient with a Combined Tremor Syndrome.

Fuente:Tremor and Other Hyperkinetic Movements (new York, N.y.)

Tipo de trabajo:Caso clínico

Extracto: This case highlights the importance of genetic screening in combined tremor disorders.

Claves:KCNQ2, kinematics, movement disorders, skin biopsy, tremor

Cita:Tremor Other Hyperkinet Mov (N Y) 2024; 14 : 24.

Autor/es:Paparella, Giulia (a)
Galosi, Eleonora (b)

institución:(a) IRCCS Neuromed, Pozzilli (IS), Italy.
(b) Department of Human Neurosciences, Sapienza University of Rome, Italy.

Conflicto:The authors have no competing interests to declare.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.5334/tohm.887

Drug- and Toxin-Induced Opsoclonus - a Systematized Review, including a Case Report on Amantadine-Induced Opsoclonus in Multiple System Atrophy.

Fuente:Tremor and Other Hyperkinetic Movements (new York, N.y.)

Tipo de trabajo:Revisión

Extracto: Toxic/drug-induced opsoclonus is very rare. The diversity of toxics/drugs impacting different neurotransmitter systems makes it challenging to define a unifying mechanism, given the intricate neuronal pathways underlying eye movement physiology and opsoclonus pathophysiology.

Claves:Drug Adverse effects, Drug-induced, Multiple system atrophy, Opsoclonus, Opsoclonus-Myoclonus Syndrome

Cita:Tremor Other Hyperkinet Mov (N Y) 2024; 14 : 23.

Autor/es:Cannilla, Hugo (a)
Messe, Maria (b)

institución:(a) University of Lausanne, Lausanne, Switzerland.
(b) Geneva University Hospitals and University of Geneva, Geneva, Switzerland.

Conflicto:The authors have no competing interests to declare.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.5334/tohm.832

Clinical analysis of transverse process fractures: A comprehensive study on patient characteristics, management, and outcomes in trauma care.

Fuente:Ulusal Travma Ve Acil Cerrahi Dergisi = Turkish Journal of Trauma & Emergency Surgery Tjtes

Tipo de trabajo:Revisión

Extracto: TPFs, previously considered minor injuries, demonstrate significant pain and functional limitations. They often accompany systemic pathologies, particularly in multilevel fractures, necessitating a multidisciplinary approach to management. The "Protection, Rest, Ice, Compression, Elevation" (PRICE) approach, including Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) and muscle relaxants, along with collar or brace support when necessary, proves effective in pain management and functional improvement. These findings emphasize the importance of recognizing TPFs as complex injuries requiring tailored management strategies. Further research and collaboration among healthcare providers are warranted to refine treatment approaches and optimize outcomes for patients with TPFs.

Cita:Ulus Travma Acil Cerrahi Derg 2024 May; 30 (5) : 353-360.

Autor/es:Günerhan, Göksal (a)
Akpınar, Afşin Emre (b)

institución:(a) Department of Neurosurgery, Health Science University, Ankara Bilkent City Hospital, Ankara-Türkiye.
(b) Department of Neurosurgery, Health Science University, Ankara Bilkent City Hospital, Ankara-Türkiye.

Formato:Informe impreso

Idioma:Inglés

País de fuente:Turquía

Sitio web:http://dx.doi.org/10.14744/tjtes.2024.91387

Zinc metabolism and its role in immunity status in subjects with trisomy 21: chromosomal dosage effect.

Zinc metabolism and its role in immunity status in subjects with trisomy 21: chromosomal dosage effect.

Fuente:Frontiers in Immunology

Extracto: DISCUSSION: Our data suggest that zinc level is not associated with the levels of immunity cells or proteins analyzed themselves and rather the main role of this ion might be played in altering immune cell function.

Claves:down syndrome, immunity disorder, integration, transcriptome, zinc

Cita:Front Immunol 2024; 15 : 1362501.

Autor/es:Ramacieri, Giuseppe (a)
Locatelli, Chiara (b)

institución:(a) Department of Medical and Surgical Sciences (DIMEC), University of Bologna, Bologna, Italy.
(b) Specialist School of Child Neuropsychiatry - University of Bologna, Bologna, Italy.

Conflicto:The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3389/fimmu.2024.1362501

The wide world of technological telerehabilitation for pediatric neurologic and neurodevelopmental disorders - a systematic review.

The wide world of technological telerehabilitation for pediatric neurologic and neurodevelopmental disorders - a systematic review.

Fuente:Frontiers in Public Health

Tipo de trabajo:Revisión sistemática

Extracto: SYSTEMATIC REVIEW REGISTRATION: PROSPERO (CRD42020210663).

Claves:children, home-based, neurodevelopmental disorders, neurological disorders, pediatric, technologies, telerehabilitation

Cita:Front Public Health 2024; 12 : 1295273.

Autor/es:Del Lucchese, Benedetta (a)
Parravicini, Stefano (b)

institución:(a) Department of Developmental Neuroscience, IRCCS Fondazione Stella Maris Foundation, Pisa, Italy.
(b) Department of Brain and Behavioral Sciences, University of Pavia, Pavia, Italy.

Conflicto:The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. The author(s) declared that they were an editorial board member of Frontiers, at the time of submission. This had no impact on the peer review process and the final decision.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3389/fpubh.2024.1295273

Endovascular Therapy and Outcomes Among Patients With Very Large Ischemic Core Stroke.

Endovascular Therapy and Outcomes Among Patients With Very Large Ischemic Core Stroke.

Fuente:Jama Network Open

Tipo de trabajo:Estudio de cohortes

Extracto: AND RELEVANCE: In this cohort study of patients with very low ASPECTS based on NCCT within 24 hours of stroke onset, those treated with EVT had higher odds of a favorable functional outcome compared with those who received SMT. Randomized clinical trials are needed to assess these findings.

Cita:JAMA Netw Open 2024 May 1; 7 (5) : e249298.

Autor/es:Xie, Dongjing (a)
Huang, Jiacheng (b)

institución:(a) Department of Neurology, Xinqiao Hospital and The Second Affiliated Hospital, Army Medical University (Third Military Medical University), Chongqing, China.
(b) Department of Neurology, Xinqiao Hospital and The Second Affiliated Hospital, Army Medical University (Third Military Medical University), Chongqing, China.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:EE.UU.

Sitio web:http://dx.doi.org/10.1001/jamanetworkopen.2024.9298

Short communication: Lifetime musical activity and resting-state functional connectivity in cognitive networks.

Short communication: Lifetime musical activity and resting-state functional connectivity in cognitive networks.

Fuente:Plos One

Tipo de trabajo:Estudio clínico

Extracto: We show that playing a musical instrument during life relates to higher RSFC of the medial prefrontal cortex with distant brain regions involved in higher-order cognitive and motor processes. Preserved or enhanced functional connectivity could potentially contribute to better brain health and resilience in OA with a history in musical activity. TRIAL REGISTRATION: German Clinical Trials Register (DRKS00007966, 04/05/2015).

Cita:PLoS One 2024; 19 (5) : e0299939.

Autor/es:Liebscher, Maxie (a)
Dell'Orco, Andrea (b)

institución:(a) German Center for Neurodegenerative Diseases (DZNE), Dresden, Germany.
(b) German Center for Neurodegenerative Diseases (DZNE), Dresden, Germany.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:EE.UU.

Sitio web:http://dx.doi.org/10.1371/journal.pone.0299939

Subthalamic nucleus synchronization between beta band local field potential and single-unit activity in Parkinson's disease.

Subthalamic nucleus synchronization between beta band local field potential and single-unit activity in Parkinson's disease.

Fuente:Physiological Reports

Extracto: Overall, these results suggest that STN single units strongly synchronize to beta activity, particularly units in areas of high beta power.

Cita:Physiol Rep 2024 May; 12 (9) : e16001.

Autor/es:Bayman, Eric (a)
Chee, Keanu (b)

institución:(a) Department of Neurosurgery, University of Colorado Anschutz Medical Campus, Aurora, Colorado, USA.
(b) Department of Neurosurgery, University of Colorado Anschutz Medical Campus, Aurora, Colorado, USA.

Formato:Informe impreso

Idioma:Inglés

País de fuente:EE.UU.

Sitio web:http://dx.doi.org/10.14814/phy2.16001