Genetic predisposition of BDNF (rs6265) gene is susceptible to Schizophrenia

Genetic predisposition of BDNF (rs6265) gene is susceptible to Schizophrenia

Fuente:Neurologia

Tipo de trabajo:Metanálisis

Extracto: Overall, the updated meta-analysis revealed that rs6265 exonic polymorphisms do not increase susceptibility to this disease. However, to better understand the pathogenesis of the disease, there is a need for further case-control studies into the BDNF polymorphism including larger sample sizes and different ethnic groups.

Claves:BDNF, Esquizofrenia, Genetic polymorphism, Meta-analysis, Metaanálisis, Neuropsychiatric disorder, Polimorfismo genético, Schizophrenia, Trastorno neuropsiquiátrico

Cita:Neurologia (Engl Ed) 2024 May; 39 (4) : 361-371.

Autor/es:Vajagathali, M (a)
Ramakrishnan, V (b)

institución:(a) Human Cytogenetics and Genomics Laboratory, Faculty of Allied Health Sciences, Chettinad Hospital and Research Institute, Chettinad Academy of Research and Education, Kelambakkam 603103, Tamilnadu, India.
(b) Human Cytogenetics and Genomics Laboratory, Faculty of Allied Health Sciences, Chettinad Hospital and Research Institute, Chettinad Academy of Research and Education, Kelambakkam 603103, Tamilnadu, India. Electronic address: rkgenes@gmail.com.

Formato:Informe impreso

Idioma:Inglés

País de fuente:España

Sitio web:http://dx.doi.org/10.1016/j.nrleng.2024.03.001

Longitudinal optical coherence tomography indices in idiopathic intracranial hypertension.

Longitudinal optical coherence tomography indices in idiopathic intracranial hypertension.

Fuente:Scientific Reports

Extracto: The time to RNFL nadir and its values correlated with IIH severity at presentation.

Claves:Idiopathic intracranial hypertension, Nadir ganglion cell complex values, Nadir retinal nerve fiber layer thickness values, Optical coherence tomography

Cita:Sci Rep 2024 Apr 14; 14 (1) : 8623.

Autor/es:Shemesh, Rachel (a)
Frige, Omry (b)

institución:(a) Neuro-Ophthalmology Unit, The Goldschleger Eye Institute, Sheba Medical Center, Tel Hashomer, Israel.
(b) Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1038/s41598-024-58865-3

Multi-organ involvement caused by Scedosporium apiospermum infection after near drowning

Multi-organ involvement caused by Scedosporium apiospermum infection after near drowning

Fuente:Bmc Neurology

Tipo de trabajo:Revisión

Extracto: While S. apiospermum infection is rare, it should be considered even in immunocompetent patients. Prompt diagnosis and treatment are essential. Voriconazole may be an effective treatment option.

Claves:Scedosporium apiospermum, Metagenomic next-generation sequencing, Multiple (brain) lesions, Normal immune function, Vision loss, Voriconazole

Cita:BMC Neurol 2024 Apr 15; 24 (1) : 124.

Autor/es:Yao, Yao (a)
Xu, Qian (b)

institución:(a) Department of Neurology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.
(b) Department of Hematology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1186/s12883-024-03637-9

Gait speed at the acute phase predicted health-related quality of life at 3 and 12 months after stroke

Gait speed at the acute phase predicted health-related quality of life at 3 and 12 months after stroke

Fuente:Journal of Rehabilitation Medicine

Tipo de trabajo:Estudio de cohortes

Extracto: Acute-phase gait speed was predictive of post-stroke HRQoL at 3 and 12 months, especially when associated with domain-specific EQ-5D-3L.

Cita:J Rehabil Med 2024 Apr 15; 56 : jrm24102.

Autor/es:Zhao, Yishuang (a)
Liao, Xiaoling (b)

institución:(a) Department of Rehabilitation Medicine, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
(b) Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China; China National Clinical Research Center for Neurological Diseases, Beijing, China.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suecia

Sitio web:http://dx.doi.org/10.2340/jrm.v56.24102

Depression risk in chronic tonsillitis patients underwent tonsillectomy: a global federated health network analysis.

Depression risk in chronic tonsillitis patients underwent tonsillectomy: a global federated health network analysis.

Fuente:International Journal of Medical Sciences

Tipo de trabajo:Estudio de cohortes

Extracto: Attention to psychological impacts following tonsillectomy is warranted to support patient well-being, leading to better management of post-tonsillectomy individuals.

Claves:cohort, depression, electronic medical records, epidemiology, tonsillectomy

Cita:Int J Med Sci 2024; 21 (5) : 949-957.

Autor/es:Chang, Hui-Chin (a)
Lu, Hsin-Yo (b)

institución:(a) Evidence-based Medicine Center, Chung Shan Medical University Hospital, Taichung, Taiwan.
(b) Library, Chung Shan Medical University Hospital, Taichung, Taiwan.

Conflicto:Competing Interests: The authors have declared that no competing interest exists.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Australia

Sitio web:http://dx.doi.org/10.7150/ijms.93977

Assessing the quality and reliability of YouTube videos as a source of information on inflammatory back pain.

Assessing the quality and reliability of YouTube videos as a source of information on inflammatory back pain.

Fuente:Peerj

Extracto: The results of the present study showed that YouTube offers videos of low reliability and low quality on inflammatory back pain. Health authorities have a responsibility to protect public health and should take proactive steps regarding health information shared on social media platforms.

Claves:Inflammatory back pain, Internet, YouTube, E-learning

Cita:PeerJ 2024; 12 : e17215.

Autor/es:Kara, Mete (a)
Ozduran, Erkan (b)

institución:(a) Department of Rheumatology, University of Health Sciences Izmir Bozyaka Education and Research Hospital, Izmir, Turkey.
(b) Department of Physical Medicine and Rehabilitation, Department of Pain Medicine, Sivas Numune Hospital, Sivas, Turkey.

Conflicto:The authors declare there are no competing interests.

Formato:Informe virtual

Idioma:Inglés

País de fuente:EE.UU.

Sitio web:http://dx.doi.org/10.7717/peerj.17215

Behind the wheel: exploring gray matter variations in experienced drivers.

Fuente:Peerj

Extracto: These findings suggest that driving skills and experience have a pronounced impact on the cortical areas responsible for low-level sensory and motor processing. Meanwhile, the influence on cortical areas associated with higher-order cognitive function appears to be minimal.

Claves:Driving experience, Driving skill, Gray matter volume, Sensory and motor processing

Cita:PeerJ 2024; 12 : e17228.

Autor/es:Chen, Jiangtao (a)
Chen, Xiaoyu (b)

institución:(a) Research Center of Brain and Cognitive Neuroscience, Liaoning Normal University, Dalian, Liaoning, China.
(b) Research Center of Brain and Cognitive Neuroscience, Liaoning Normal University, Dalian, Liaoning, China.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:EE.UU.

Sitio web:http://dx.doi.org/10.7717/peerj.17228

Enhancing fear extinction.

Fuente:Elife

Extracto: radually reducing a source of fear during extinction treatments may weaken negative memories in the long term.

Claves:extinction, memory, neuroscience, prediction error, rat

Cita:Elife 2024 Apr 15; 13

Autor/es:Trask, Sydney (a)
Ferrara, Nicole C (b)

institución:(a) Department of Psychological Sciences, Purdue University West Lafayette, West Lafayette, United States.
(b) Purdue Institute for Integrative Neuroscience, Purdue University West Lafayette, West Lafayette, United States.

Conflicto:ST, NF No competing interests declared

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.7554/eLife.97633

Combining mHealth Technology and Pharmacotherapy to Improve Mental Health Outcomes and Reduce Human Rights Abuses in West Africa: Intervention Field Trial.

Combining mHealth Technology and Pharmacotherapy to Improve Mental Health Outcomes and Reduce Human Rights Abuses in West Africa: Intervention Field Trial.

Fuente:Jmir Mental Health

Extracto: The M&M intervention proved to be feasible, acceptable, safe, and clinically promising. Preliminary findings suggest that the M-Healer toolkit may have shifted healers' behaviors at the prayer camp so that they commit fewer human rights abuses.

Claves:Africa, CAM, abuse, alternative, app, applications, apps, behavior change, behaviour change, bipolar, bipolar disorder, complementary, depression, depressive, feasibility, acceptability, safety, healer, healers, human rights, mHealth, medication, medications, mental, mobile health, pharmacological, pharmacology, pharmacotherapy, psychosocial, schizophrenia, schizophrenic, schizophrenics, training

Cita:JMIR Ment Health 2024 Mar 27; 11 : e53096.

Autor/es:Ben-Zeev, Dror (a)
Larsen, Anna (b)

institución:(a) Behavioral Research in Technology and Engineering Center, Department of Psychiatry and Behavioral Sciences, University of Washington, Seattle, WA, United States.
(b) Behavioral Research in Technology and Engineering Center, Department of Psychiatry and Behavioral Sciences, University of Washington, Seattle, WA, United States.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Canadá

Sitio web:http://dx.doi.org/10.2196/53096

Perceived Physical Health and Cognitive Behavioral Therapy vs Supportive Psychotherapy Outcomes in Adults With Late-Life Depression

Perceived Physical Health and Cognitive Behavioral Therapy vs Supportive Psychotherapy Outcomes in Adults With Late-Life Depression

Fuente:Jama Network Open

Tipo de trabajo:Estudio clínico aleatorizado

Extracto: AND RELEVANCE: In this secondary analysis of a randomized clinical trial, subjective PPH was associated with treatment outcome, response, and remission in psychotherapy of LLD. Patients with LLD responded differently to LLD-CBT and SUI, depending on their baseline PPH score. Treatment approaches for patients with LLD should address PPH in personalized interventions. TRIAL REGISTRATION: ClinicalTrials.gov Identifier: NCT03735576; Deutsches Register Klinischer Studien Identifier: DRKS00013769.

Cita:JAMA Netw Open 2024 Apr 1; 7 (4) : e245841.

Autor/es:Dafsari, Forugh S (a)
Bewernick, Bettina (b)

institución:(a) Department of Psychiatry and Psychotherapy, University of Cologne, Faculty of Medicine, and University Hospital Cologne, Cologne, Germany.
(b) Department of Neurodegenerative Diseases and Geriatric Psychiatry, University of Bonn, Bonn, Germany.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:EE.UU.

Sitio web:http://dx.doi.org/10.1001/jamanetworkopen.2024.5841

Repurposing non-pharmacological interventions for Alzheimer's disease through link prediction on biomedical literature.

Repurposing non-pharmacological interventions for Alzheimer's disease through link prediction on biomedical literature.

Fuente:Scientific Reports

Extracto: The proposed framework shows potential for discovering new NPIs for AD prevention and understanding their mechanistic pathways.

Cita:Sci Rep 2024 Apr 15; 14 (1) : 8693.

Autor/es:Xiao, Yongkang (a)
Hou, Yu (b)

institución:(a) Institute for Health Informatics, University of Minnesota, Minneapolis, MN, USA.
(b) Division of Computational Health Sciences, Department of Surgery, University of Minnesota, Minneapolis, MN, USA.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1038/s41598-024-58604-8

Tactile shape discrimination for moving stimuli.

Fuente:Scientific Reports

Extracto: These discoveries deepen our understanding of tactile perception mechanisms and underscore the criticality of predictions in sensory information processing.

Cita:Sci Rep 2024 Apr 15; 14 (1) : 8707.

Autor/es:Pélegrin, Nicolas (a)
Konishi, Mahiko (b)

institución:(a) ONERA, Information Processing and Systems Department, Cognitive Engineering and Applied Neurosciences Research Unit, Salon-de-Provence, 13661, France. nico_pelegrin@orange.fr.
(b) Jellysmack, Paris, 75008, France.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1038/s41598-024-58509-6

Systematic culture of central catheters and infections related to catheters in a neonatal intensive care unit: an observational study.

Fuente:Scientific Reports

Extracto: Performing a catheter culture only if catheter-related infection is suspected could be an alternative to routine screening.

Cita:Sci Rep 2024 Apr 15; 14 (1) : 8647.

Autor/es:Mazuel, Marie (a)
Moulier, Virginie (b)

institución:(a) Neonatal Intensive Care Unit, Assistance Publique-Hôpitaux de Paris, Robert Debré Children's Hospital, Paris, France.
(b) University Department of Psychiatry, Centre d'Excellence Thérapeutique, Institut de Psychiatrie, Centre hospitalier du Rouvray, Sotteville-lès-Rouen, France.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1038/s41598-024-59371-2

Individuals vary in their overt attention preference for positive images consistently across time and stimulus types.

Fuente:Scientific Reports

Extracto: We discuss the possible practical diagnostic applications of these findings, as well as how this general gaze-related trait may influence other behavioral and psychological aspects.

Claves:Depression, Eye tracking, Individual differences, Positivity preference, Valence

Cita:Sci Rep 2024 Apr 15; 14 (1) : 8712.

Autor/es:Guy, Nitzan (a)
Sklar, Asael Y (b)

institución:(a) Department of Psychology, Hebrew University of Jerusalem, Jerusalem, Israel.
(b) Department of Psychology, Tel Aviv University, Tel Aviv, Israel.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1038/s41598-024-58987-8

Safety and efficacy of the novel Alpha stent for the treatment of intracranial wide-necked aneurysm.

Fuente:Scientific Reports

Extracto: The recent structural modifications allowed for easier stent delivery and deployment.Clinical trial registration number: KCT0005841; registration date: 28/01/2021.

Cita:Sci Rep 2024 Apr 16; 14 (1) : 8723.

Autor/es:Kim, Junhyung (a)
Kim, Jung-Jae (b)

institución:(a) Department of Neurosurgery, Severance Hospital, Yonsei University College of Medicine, Seoul, Republic of Korea.
(b) Department of Neurosurgery, Severance Hospital, Yonsei University College of Medicine, Seoul, Republic of Korea.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1038/s41598-024-59363-2

Integrating 'undetectable equals untransmittable' into HIV counselling in South Africa: the development of locally acceptable communication tools using intervention mapping.

Integrating 'undetectable equals untransmittable' into HIV counselling in South Africa: the development of locally acceptable communication tools using intervention mapping.

Fuente:Bmc Public Health

Tipo de trabajo:Revisión sistemática

Extracto: We outline an intervention development strategy, currently in evaluation stage, utilizing IM with formative research and input from key U = U stakeholders and people living with HIV (PLHIV).

Claves:Intervention, Intervention mapping, South Africa, Treatment-as-prevention, U = U

Cita:BMC Public Health 2024 Apr 15; 24 (1) : 1052.

Autor/es:Sineke, Tembeka (a)
Bor, Jacob (b)

institución:(a) Health Economics and Epidemiology Research Office, School of Public Health, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.
(b) Faculty of Psychology and Neuroscience, Maastricht University, Maastricht, the Netherlands.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1186/s12889-024-18471-4

Impulsivity mediates the association between narcissism and substance-related problems beyond the degree of substance use: a longitudinal observational study.

Impulsivity mediates the association between narcissism and substance-related problems beyond the degree of substance use: a longitudinal observational study.

Fuente:Bmc Psychiatry

Extracto: In conclusion, narcissistic individuals may not use substances more but have a higher SUD risk, informing prevention and treatment.

Claves:Addiction, Impulsivity, Narcissism, Substance use disorder, Substance use motives

Cita:BMC Psychiatry 2024 Apr 15; 24 (1) : 280.

Autor/es:Hildebrandt, Malin K (a)
Noack, Josepha (b)

institución:(a) Institute of Clinical Psychology and Psychotherapy, Chair of Addiction Research, Faculty of Psychology, Technische Universität Dresden, Chemnitzer Str. 46a, 01187, Dresden, Germany. malin.hildebrandt@googlemail.com.
(b) Institute of Clinical Psychology and Psychotherapy, Chair of Addiction Research, Faculty of Psychology, Technische Universität Dresden, Chemnitzer Str. 46a, 01187, Dresden, Germany.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1186/s12888-024-05718-y

Multicenter registry study of cerebral venous thrombosis in china (RETAIN-CH): Rationale and design.

Multicenter registry study of cerebral venous thrombosis in china (RETAIN-CH): Rationale and design.

Fuente:Brain and Behavior

Tipo de trabajo:Estudio de cohortes

Extracto: IDENTIFIER: NCT05448248.

Claves:cerebral venous thrombosis, cohort study, endovascular treatment, protocol, safety

Cita:Brain Behav 2024 Apr; 14 (4) : e3353.

Autor/es:Bian, Hetao (a)
Wang, Xia (b)

institución:(a) Beijing Institute for Brain Disorders, Capital Medical University, Beijing, China.
(b) The George Institute for Global Health, University of New South Wales, Sydney, Australia.

Formato:Informe impreso

Idioma:Inglés

País de fuente:EE.UU.

Sitio web:http://dx.doi.org/10.1002/brb3.3353

Cerebral Venous Sinus Thrombosis as an Initial Presentation of Nephrotic Syndrome

Cerebral Venous Sinus Thrombosis as an Initial Presentation of Nephrotic Syndrome

Fuente:Vascular Health and Risk Management

Tipo de trabajo:Caso clínico

Extracto: She was managed with low molecular weight heparin and intervenous corticosteroids then shifted to rivaroxaban and oral steroids, respectively, which resulted in massive clinical improvement and resolution of thrombus.

Claves:MR venography, cerebral venous sinus thrombosis, nephrotic syndrome

Cita:Vasc Health Risk Manag 2024; 20 : 177-181.

Autor/es:Balla, Yassir (a)
Hashi, Abdullahi Said (b)

institución:(a) Department of Internal Medicine, Somali-Sudanese Specialized hospital, Mogadishu, Somalia.
(b) Department of Anesthesiology and Reanimation, Mogadishu Somalia Turkish Training and Research Hospital, Mogadishu, Somalia.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Nueva Zelanda

Sitio web:http://dx.doi.org/10.2147/VHRM.S458539

Emotional State Transitions in Trauma-Exposed Individuals With and Without Posttraumatic Stress Disorder.

Emotional State Transitions in Trauma-Exposed Individuals With and Without Posttraumatic Stress Disorder.

Fuente:Jama Network Open

Extracto: AND RELEVANCE: These findings support that individuals with PTSD undergo rapid transitions between neutral and negative emotional states, a phenomenon intensified by the severity of emotional numbing symptoms. Therapeutic interventions aimed at moderating these swift emotional transitions could potentially alleviate PTSD symptoms.

Cita:JAMA Netw Open 2024 Apr 1; 7 (4) : e246813.

Autor/es:Korem, Nachshon (a)
Duek, Or (b)

institución:(a) Department of Psychiatry, Yale University School of Medicine, New Haven, Connecticut.
(b) Department of Comparative Medicine, Yale University School of Medicine, New Haven, Connecticut.

Conflicto:Conflict of Interest Disclosures: Dr Harpaz-Rotem reported receiving grants from Boehringer Ingelheim International GmbH outside the submitted work. No other disclosures were reported.

Formato:Informe virtual

Idioma:Inglés

País de fuente:EE.UU.

Sitio web:http://dx.doi.org/10.1001/jamanetworkopen.2024.6813