Efficacy of the Flo App in Improving Health Literacy, Menstrual and General Health, and Well-Being in Women: Pilot Randomized Controlled Trial.

Efficacy of the Flo App in Improving Health Literacy, Menstrual and General Health, and Well-Being in Women: Pilot Randomized Controlled Trial.

Fuente:Jmir Mhealth and Uhealth

Tipo de trabajo:Estudio aleatorizado y controlado

Extracto: These pilot randomized controlled trials demonstrate that the use of the Flo app improves menstrual health literacy and awareness, general health and well-being, and PMS or PMDD symptom burden. Considering the widespread use and affordability of the Flo app, these findings show promise for filling important gaps in current health care provisioning such as improving menstrual knowledge and health. TRIAL REGISTRATION: OSF Registries osf.io/pcgw7; https://osf.io/pcgw7 ; OSF Registries osf.io/ry8vq; https://osf.io/ry8vq.

Claves:PMDD, PMS, app, application, awareness, communication, digital health, education, efficacy, functionality, general health, health literacy, health management, manage, management, menstrual, menstrual cycle, period tracking app, pregnancy, premenstrual, premenstrual dysphoric disorder, premenstrual syndrome, productivity, quality of life, randomized controlled trial, reproductive, reproductive health, symptoms, tracking, tracking app, tracking application, wellbeing, women, women’s health

Cita:JMIR Mhealth Uhealth 2024 May 2; 12 : e54124.

Autor/es:Cunningham, Adam C (a)
Prentice, Carley (b)

institución:(a) Flo Health UK Limited, London, United Kingdom.
(b) Flo Health UK Limited, London, United Kingdom.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Canadá

Sitio web:http://dx.doi.org/10.2196/54124

Pituitary abscess: a descriptive analysis of a series of 19 patients-a multi-center experience.

Pituitary abscess: a descriptive analysis of a series of 19 patients-a multi-center experience.

Fuente:European Journal of Medical Research

Extracto: Given the lack of clarity in preoperative diagnosis, typical intraoperative findings and effective antibiotics treatment are more indicative of the correct diagnosis than other tests. In terms of therapy, optimal surgical intervention and active postoperative antibiotic treatment contribute to resolving the challenges posed by PA.

Claves:Diagnosis, PA, Transsphenoidal surgery, Treatment

Cita:Eur J Med Res 2024 May 2; 29 (1) : 262.

Autor/es:Xue, Qiang (a)
Shi, Xiuhua (b)

institución:(a) Departments of Neurosurgery, The Third Affiliated Hospital, Naval Medical University, Shanghai, 200438, China.
(b) Department of Radiotherapy & Oncology, The No. 2 People's Hospital of Wuhu City, Wuhu, Anhui, China.

Conflicto:No competing financial interests exist.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1186/s40001-024-01749-z

Interaction of obesity and proteins associated with the NLRP3 inflammasome following mild traumatic brain injury.

Interaction of obesity and proteins associated with the NLRP3 inflammasome following mild traumatic brain injury.

Fuente:Scientific Reports

Extracto: In this single center mTBI cohort, obese BMI interacted with higher acute concentrations of NLRP3 inflammasome proteins and worsened short- and long-term clinical outcomes.

Cita:Sci Rep 2024 May 3; 14 (1) : 10178.

Autor/es:Eagle, Shawn R (a)
Basantani, Mahesh K (b)

institución:(a) Department of Neurological Surgery, University of Pittsburgh, 3550 Terrace St, Pittsburgh, PA, 15261, USA. eaglesr2@upmc.edu.
(b) Division of Endocrinology and Metabolism, Department of Medicine, University of Pittsburgh, Pittsburgh, PA, USA.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1038/s41598-024-61089-0

Diabetic peripheral neuropathy: age-stratified glycemic control.

Diabetic peripheral neuropathy: age-stratified glycemic control.

Fuente:Frontiers in Endocrinology

Extracto: Suboptimal glycemic control at baseline, rather than at the end of the study period, predicts an increased risk of future DPN in individuals with T2DM under age 65. This correlation is not seen in elderly patients. Therefore, we recommend implementing enhanced glycemic control early in middle-aged T2DM patients and propose individualized therapeutic strategies for diabetes in different age groups.

Claves:age, diabetic peripheral neuropathy, glycemic control, risk factor, type 2 diabetes mellitus

Cita:Front Endocrinol (Lausanne) 2024; 15 : 1377923.

Autor/es:Wang, Chi-Sheng (a)
Pai, Yen-Wei (b)

institución:(a) Neurological Institute, Taichung Veterans General Hospital, Taichung, Taiwan.
(b) Neurological Institute, Taichung Veterans General Hospital, Taichung, Taiwan.

Conflicto:The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3389/fendo.2024.1377923

Association between arterial health and cognition in adolescents: The PANIC study.

Association between arterial health and cognition in adolescents: The PANIC study.

Fuente:Physiological Reports

Extracto: Results suggest that preventing high blood pressure is important for promoting cognition in adolescents.

Claves:arterial stiffness, blood pressure, carotid intima‐media thickness, physical activity, sedentary time

Cita:Physiol Rep 2024 May; 12 (9) : e16024.

Autor/es:Jalanko, Petri (a)
Bond, Bert (b)

institución:(a) Faculty of Sport and Health Sciences, University of Jyväskylä, Jyväskylä, Finland.
(b) Helsinki Clinic for Sports and Exercise Medicine, Foundation for Sports and Exercise Medicine, Helsinki, Finland.

Conflicto:The author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.

Formato:Informe impreso

Idioma:Inglés

País de fuente:EE.UU.

Sitio web:http://dx.doi.org/10.14814/phy2.16024

Self-initiated lifestyle changes during a fasting-mimicking diet programme in patients with type 2 diabetes: a mixed-methods study.

Self-initiated lifestyle changes during a fasting-mimicking diet programme in patients with type 2 diabetes: a mixed-methods study.

Fuente:Bmc Primary Care

Extracto: Using an FMD for five consecutive days per month did not affect diet quality in between FMD periods in quantitative analysis, but increased the number of hours per week spent on physical activity. Qualitative analysis revealed self-initiated improvements in both diet quality and physical activity in individual participants using an FMD. Healthcare professionals could use an FMD programme as a 'teachable moment' to stimulate additional lifestyle changes. TRIAL REGISTRATION: ClinicalTrials.gov; NCT03811587. Registered 22 January 2019.

Claves:Diet, Dietary behaviour, Fasting-mimicking diet, Intermittent energy restriction, Mixed-methods, Periodic fasting, Physical activity, Self-initiated behavioural change, Type 2 diabetes

Cita:BMC Prim Care 2024 May 2; 25 (1) : 148.

Autor/es:van den Burg, Elske L (a)
Schoonakker, Marjolein P (b)

institución:(a) Department of Public Health and Primary Care, Leiden University Medical Centre (LUMC), Postzone V0-P, Postbus 9600, 2300 RC, Leiden, The Netherlands. e.l.van_den_burg@lumc.nl.
(b) Department of Public Health and Primary Care, Leiden University Medical Centre (LUMC), Postzone V0-P, Postbus 9600, 2300 RC, Leiden, The Netherlands.

Conflicto:HL has received consulting fees from Royal Philips and was member of the board of trustees of the SCMR and UEMS section Radiology without payment. All authors declare that they have no other competing interests.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1186/s12875-024-02405-5

Alzheimer's disease as a causal risk factor for diabetic retinopathy: a Mendelian randomization study.

Alzheimer's disease as a causal risk factor for diabetic retinopathy: a Mendelian randomization study.

Fuente:Frontiers in Endocrinology

Extracto: DISCUSSION: This study underscores the contribution of AD to an increased risk of DR, as well as NPDR and PDR subtypes, underscoring the necessity of a holistic approach in the management of patients affected by these conditions.

Claves:Alzheimer’s disease, FUMA, Mendelian randomization, causal association, diabetic retinopathy

Cita:Front Endocrinol (Lausanne) 2024; 15 : 1340608.

Autor/es:Ouyang, Fu (a)
Yuan, Ping (b)

institución:(a) Department of Neurology, the Affiliated Hospital of Guizhou Medical University, Guiyang, Guizhou, China.
(b) Department of Neurology, the Affiliated Hospital of Guizhou Medical University, Guiyang, Guizhou, China.

Conflicto:The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3389/fendo.2024.1340608

Decoding emotional resilience in aging: unveiling the interplay between daily functioning and emotional health.

Decoding emotional resilience in aging: unveiling the interplay between daily functioning and emotional health.

Fuente:Frontiers in Public Health

Extracto: This study, employing various statistical methods, identified a negative correlation between ADL and EPs, with machine learning algorithms confirming this finding. Impaired ADL increases susceptibility to EPs.

Claves:Barthel index (BI), activities of daily living (ADL), decision tree (DT), emotional problems (EPs), logistic regression (LR), machine learning algorithm, support vector machine (SVM), the China health and retirement longitudinal survey (CHARLS)

Cita:Front Public Health 2024; 12 : 1391033.

Autor/es:Guo, Minhua (a)
Xu, Songyang (b)

institución:(a) School of Integrated Chinese and Western Medicine, Hunan University of Chinese Medicine, Changsha, Hunan, China.
(b) Key Laboratory of Hunan Province for Integrated Traditional Chinese and Western Medicine on Prevention and Treatment of Cardio-Cerebral Diseases, College of Integrated Traditional Chinese and Western Medicine, Hunan University of Chinese Medicine, Changsha, Hunan, China.

Conflicto:The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3389/fpubh.2024.1391033

Neurological affection and serum neurofilament light chain in wild type transthyretin amyloidosis.

Neurological affection and serum neurofilament light chain in wild type transthyretin amyloidosis.

Fuente:Scientific Reports

Extracto: It will be important to consider neurological aspects of A-ATTRwt for diagnosis, clinical follow-up, and future treatment development.

Cita:Sci Rep 2024 May 2; 14 (1) : 10111.

Autor/es:Pernice, Helena F (a)
Knorz, Adrian L (b)

institución:(a) Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Amyloidosis Center Charité Berlin (ACCB), Charitéplatz 1, 10117, Berlin, Germany.
(b) Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Department of Neurology and Experimental Neurology, Charitéplatz 1, 10117, Berlin, Germany.

Conflicto:Helena Pernice has received personal funding, travel support, and speaker fees by Alnylam Pharmaceuticals Inc. HP also received personal funding by Deutsche Gesellschaft für Muskelkranke (DGM) GmbH. Adrian Knorz, Gunnar Fiß, Harisa Muratovic, Paul Wetzel, Finn Rieber, Carolin Herrmann and Eleonora Asaad declare they have no conflict of interest. Katrin Hahn received financial reimbursement for consulting, advisory board activities, speaker... er fees and/or contributions to congresses and travel support to attend scientific meetings by Akcea Therapeuticals Inc., Alnylam Pharmaceuticals Inc., Amicus, AstraZeneca, GSK, Hormosan, Takeda Pharmaceutical Inc., Pfizer Pharmaceuticals Inc., Swedish Orphan Biovitrum Inc and ViiV Healthcare GmbH. KH further received research funding by the foundation Charité (BIH clinical fellow), Alnylam Pharmaceuticals Inc., and Pfizer Pharmaceuticals. Fabian Knebel received speaker honoraria from Alnylam Inc., Pfizer Inc., and research support from Alnylam Inc and Pfizer Inc. Christoph Wetz received a speaker honorarium from Company Novartis, Pfizer and Alnylam Pharmaceuticals; and received grants/research support from Novartis. Bettina Heidecker has received speaker fees and research funding from Pfizer Pharmaceuticals Inc., AstraZeneca, and Boehringer Ingelheim unrelated to this project. Fabian Knebel received speaker honoraria from Alnylam Inc., Pfizer Inc., and research support from Alnylam Inc and Pfizer Inc. Sebastian Spethmann received financial reimbursement for lectures from Pfizer Pharmaceuticals. Elisabeth Blüthner received consultation, lecture, advisory board honoraria and grant research support from Takeda Pharmaceuticals Inc. Anna Brand received a speaker honorarium from Pfizer. Daniel Messroghli has received honoraria for speaking at symposia from Pfizer, Alnylam and Akcea and research funding from Pfizer. Carsten Tschöpe has received speaker fees and/or contributions to congresses from Abbott, Abiomed, Astra Zeneca, Bayer, Novartis, Pfizer, and Servier; all outside the submitted work. Gina Barzen received personal funding by Alnylam Pharmaceuticals Inc.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1038/s41598-024-60025-6

Association between advanced lung cancer inflammation index and all-cause and cardiovascular mortality among stroke patients: NHANES, 1999-2018.

Association between advanced lung cancer inflammation index and all-cause and cardiovascular mortality among stroke patients: NHANES, 1999-2018.

Fuente:Frontiers in Public Health

Extracto: This was the first study on the relationship between ALI and all-cause and CVD mortality in stroke patients. Elevated ALI was closely associated with a reduced risk of all-cause mortality. A reverse J-shaped non-linear relationship existed between the two, with an inflection point at 83.76. These findings implied that controlling the ALI of stroke patients within an appropriate range was crucial for their prognosis (such as weight management, albumin supplementation, anti-inflammatory treatment). The dynamic variation in ALI was also advantageous for clinicians in establishing personalized ALI criteria to maximize the long-term survival of stroke patients.

Claves:CVD mortality, National Health and Nutrition Examination Survey, advanced lung cancer inflammation index, all-cause mortality, stroke

Cita:Front Public Health 2024; 12 : 1370322.

Autor/es:Chen, Xiaokun (a)
Hong, Chunzhan (b)

institución:(a) Department of Neurology, The Second Affiliated Hospital, Fujian Medical University, Quanzhou, China.
(b) Department of Neurology, The Second Affiliated Hospital, Fujian Medical University, Quanzhou, China.

Conflicto:The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3389/fpubh.2024.1370322

Association between vitamin B2 intake and prostate-specific antigen in American men: 2003-2010 National Health and Nutrition Examination Survey.

Association between vitamin B2 intake and prostate-specific antigen in American men: 2003-2010 National Health and Nutrition Examination Survey.

Fuente:Bmc Public Health

Extracto: Our study in American men has unveiled a notable inverse association between vitamin B2 intake and PSA levels, potentially posing a challenge for the identification of asymptomatic prostate cancer. Specifically, our findings suggest that individuals with higher vitamin B2 intake may be at a greater risk of being diagnosed with advanced prostate cancer in the future, possibly indicating a detection bias. These results may offer a novel explanation for the observed positive correlation between vitamin B2 intake and prostate cancer.

Claves:National Health and Nutrition Examination Survey (NHANES), Prostate cancer, Prostate-specific antigen, Vitamin B2

Cita:BMC Public Health 2024 May 3; 24 (1) : 1224.

Autor/es:Lv, Jia-Jie (a)
Zhang, Lin-Jie (b)

institución:(a) Department of Vascular Surgery, Shanghai Putuo People's Hospital, School of Medicine, Tongji University, Huangpu District, No.1291 Jiangning Road, Shanghai, 200060, China.
(b) Department of Vascular Surgery, Shanghai Ninth People's Hospital, Shanghai JiaoTong University School of Medicine, Huangpu District, No.639 Zhizaoju Road, Shanghai, 200011, PR China.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1186/s12889-024-18582-y

Laser Interstitial Thermotherapy (LITT) in Recurrent Glioblastoma: What Window of Opportunity for This Treatment?

Fuente:Technology in Cancer Research & Treatment

Extracto: Well-designed prospective studies will be needed to establish with certainty the role of Laser Interstitial Thermotherapy in the treatment of recurrent glioma.

Claves:brain tumor, glioblastoma, glioma, laser interstitial thermotherapy, radiation necrosis, stereotactic laser ablation, thermotherapy

Cita:Technol Cancer Res Treat 2024 Jan-Dec; 23 : 15330338241249026.

Autor/es:Morello, Alberto (a)
Bianconi, Andrea (b)

institución:(a) Neurosurgery Unit, Department of Neuroscience "Rita Levi Montalcini", "Città della Salute e della Scienza" University Hospital, University of Turin, Turin, Italy. RINGGOLD: 18691
(b) Department of Neurosurgery, Clinical Neuroscience Center, University Hospital Zurich, University of Zurich, Zurich, Switzerland. RINGGOLD: 204563

Conflicto:Declaration of Conflicting InterestsThe author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.

Formato:Informe impreso

Idioma:Inglés

País de fuente:EE.UU.

Sitio web:http://dx.doi.org/10.1177/15330338241249026

Advances in the Endovascular Management of Cerebrovascular Disease.

Fuente:Missouri Medicine

Extracto: This article explores the advancements in endovascular neurosurgical techniques, highlighting the impact on patient care, outcomes, and the evolution of traditional surgical methods.

Cita:Mo Med 2024 Mar-Apr; 121 (2) : 127-135.

Autor/es:Nunna, Ravi (a)
Tariq, Farzana (b)

institución:(a) Department of Neurosurgery, University of Missouri-Columbia School of Medicine, Columbia, Missouri.
(b) Department of Neurosurgery, University of Missouri-Columbia School of Medicine, Columbia, Missouri.

Conflicto:Disclosure: No financial disclosures reported. Artificial intelligence was not used in the study, research, preparation, or writing of this manuscript.

Formato:Informe impreso

Idioma:Inglés

País de fuente:EE.UU.

Sitio web:

Cutting Edge Developments in Spine Surgery at the University of Missouri.

Fuente:Missouri Medicine

Extracto: This integration of innovation demonstrates our tireless commitment to ensuring excellence in the comprehensive care of a diverse range of patients with complex spinal pathologies.

Cita:Mo Med 2024 Mar-Apr; 121 (2) : 142-148.

Autor/es:Nunna, Ravi (a)
Tariq, Farzana (b)

institución:(a) Department of Neurosurgery, University of Missouri - Columbia, Columbia, Missouri.
(b) Department of Neurosurgery, University of Missouri - Columbia, Columbia, Missouri.

Conflicto:Disclosure: No financial disclosures reported. Artificial intelligence was not used in the study, research, preparation, or writing of this manuscript.

Formato:Informe impreso

Idioma:Inglés

País de fuente:EE.UU.

Sitio web:

Advances in Cranial Surgery.

Fuente:Missouri Medicine

Extracto: This paper review advances in treatment of intracranial pathologies, and how the neurosurgeons and other medical providers at the University of Missouri-Columbia (UMC) are optimizing these treatments for their patients.

Cita:Mo Med 2024 Mar-Apr; 121 (2) : 136-141.

Autor/es:Tariq, Farzana (a)
Jumah, Fareed (b)

institución:(a) Department of Neurosurgery, University of Missouri - Columbia, Columbia, Missouri.
(b) Department of Neurosurgery, University of Missouri - Columbia, Columbia, Missouri.

Conflicto:Disclosure: No financial disclosures reported. Artificial intelligence was not used in the study, research, preparation, or writing of this manuscript.

Formato:Informe impreso

Idioma:Inglés

País de fuente:EE.UU.

Sitio web:

Role of Functional neurosurgery in Improving Patient Outcomes in Epilepsy, Movement Disorders, and Chronic Pain.

Fuente:Missouri Medicine

Extracto: This review outlines the role functional neurosurgery plays in treatment of epilepsy, movement disorders, and pain, and how it is being implemented at the University of Missouri by the Department of Neurosurgery.

Cita:Mo Med 2024 Mar-Apr; 121 (2) : 149-155.

Autor/es:Chen, Wesley (a)
Tariq, Farzana (b)

institución:(a) Department of Neurosurgery, University of Missouri - Columbia, Columbia, Missouri.
(b) Department of Neurosurgery, University of Missouri - Columbia, Columbia, Missouri.

Conflicto:Disclosure: No financial disclosures reported. Artificial intelligence was not used in the study, research, preparation, or writing of this manuscript.

Formato:Informe impreso

Idioma:Inglés

País de fuente:EE.UU.

Sitio web:

A Biosynthetic Alternative to Human Amniotic Membrane for Use in Ocular Surface Surgery.

Fuente:Translational Vision Science & Technology

Extracto: These results indicate that the SM is a better substrate for limbal epithelial cell migration, proliferation, and tight junction formation. Altogether, the SM can provide a suitable alternative to the hAM for surgical application in sight-restoring operations. TRANSLATIONAL RELEVANCE: The hAM, currently widely used in ocular surface surgery, has numerous variations and limitations. The biocompatibility of corneal epithelial cells with the SM demonstrated in this study suggests that it can be a viable substitute for the hAM.

Cita:Transl Vis Sci Technol 2024 May 1; 13 (5) : 3.

Autor/es:Sahay, Prity (a)
Behbehani, Mehri (b)

institución:(a) Academic Ophthalmology, Division of Clinical Neuroscience, School of Medicine, University of Nottingham, UK.
(b) The Electrospinning Company, Oxfordshire, UK.

Formato:Informe impreso

Idioma:Inglés

País de fuente:EE.UU.

Sitio web:http://dx.doi.org/10.1167/tvst.13.5.3

A Magnetic Actuator Device for Fully Automated Blinking in Total Bidirectional Eyelid Paralysis: First Proof of Concept in a Human Participant.

Fuente:Translational Vision Science & Technology

Extracto: FEA simulation results conformed to the experimentally observed trend, further supporting the proof of concept and design parameters. This is the first viable approach in human patients with proof of concept for complete reanimation of a bidirectionally paretic eyelid. Further study is warranted to refine the prototype and determine the feasibility and safety of prolonged use. TRANSLATIONAL RELEVANCE: This is first proof of concept for our device for total bidirectional eyelid paralysis.

Cita:Transl Vis Sci Technol 2024 May 1; 13 (5) : 2.

Autor/es:Houston, Kevin E (a)
Singh, Manarshhjot (b)

institución:(a) Departments of Neurology and Ophthalmology, University of Massachusetts Chan Medical School, Worcester, MA, USA.
(b) Department of Neurology, University of Massachusetts Chan Medical School, Worcester, MA, USA.

Formato:Informe impreso

Idioma:Inglés

País de fuente:EE.UU.

Sitio web:http://dx.doi.org/10.1167/tvst.13.5.2

Differential neural correlates underlying visuospatial versus semantic reasoning in autistic children.

Fuente:Cerebral Cortex (new York, N.y. 1991)

Extracto: Our results add to several studies now demonstrating that the connectivity alterations in autistic relative to neurotypical individuals are much more complex than previously thought and depend on both task type and task complexity and their respective underlying cognitive processes.

Claves:autism, children, fMRI, functional connectivity, reasoning, visuospatial

Cita:Cereb Cortex 2024 May 2; 34 (13) : 19-29.

Autor/es:Degré-Pelletier, Janie (a)
Danis, Éliane (b)

institución:(a) Laboratory on Intelligence and Development in Autism, Department of Psychology, Université du Québec à Montréal, C.P. 8888 Succursale Centre-Ville, Montreal, Quebec H3C 3P8, Canada.
(b) Montreal Cognitive Neuroscience Autism Research Group, CIUSSS du Nord-de-l'île-de-Montreal, 7070, Boulevard Perras, Montréal, Quebec H1E 1A4, Canada.

Formato:Informe impreso

Idioma:Inglés

País de fuente:EE.UU.

Sitio web:http://dx.doi.org/10.1093/cercor/bhae093

MOG Antibody-Associated Disease in the Setting of Metastatic Melanoma Complicated by Immune Checkpoint Inhibitor Use.

Fuente:Neurology(r) Neuroimmunology & Neuroinflammation

Tipo de trabajo:Caso clínico

Extracto: We highlight tocilizumab as a dual-purpose treatment of MOGAD and the neurologic immune-related adverse effect of ICI.

Cita:Neurol Neuroimmunol Neuroinflamm 2024 Jul; 11 (4) : e200249.

Autor/es:Syc-Mazurek, Stephanie B (a)
Zhao-Fleming, Hannah (b)

institución:(a) From the Departments of Neurology (S.B.S.-M., H.Z.-F., Y.G., N.T., J.J.C., A.Z., C.F.L., R.M., E.P.F.), Ophthalmology (J.J.C.), Internal Medicine (I.K.), and Oncology (J.J.O., M.S.B.), Mayo Clinic, Rochester, MN; and Neurology (C.F.L.), University of Texas at Austin.
(b) From the Departments of Neurology (S.B.S.-M., H.Z.-F., Y.G., N.T., J.J.C., A.Z., C.F.L., R.M., E.P.F.), Ophthalmology (J.J.C.), Internal Medicine (I.K.), and Oncology (J.J.O., M.S.B.), Mayo Clinic, Rochester, MN; and Neurology (C.F.L.), University of Texas at Austin.

Conflicto:S.B. Syc-Mazurek is an editor of the Neurology Resident & Fellows Section. H.H. Zhao-Fleming reports no disclosures relevant to the manuscript. Y. Guo reports no disclosures relevant to the manuscript. N. Tisavipat reports no disclosures relevant to the manuscript. J.J. Chen reports payment for consultation from UCB and Horizon. A. Zekeridou has patents submitted on Tenascin-R-IgG, PDE10A-IgG, and DACH1-IgG as... biomarkers of neurologic autoimmunity; has consulted for Alexion Pharmaceuticals without personal compensation and received research funding from Roche/Genetech not relevant to the current work. I. Kournoutas reports no disclosures relevant to the manuscript. J.J. Orme is supported by a Prostate Cancer Foundation Young Investigator Award, has received research support from Nanotics and Genentech, and has received consulting fees from Nanotics and Partner Therapeutics. M. S. Block receives institutional research support from Alkermes, Bristol-Myers Squibb, Genentech, Merck, nFerence, Pharmacyclics, Regeneron, Sorrento, TILT Biotherapeutics, Transgene, and Viewpoint Molecular Therapeutics. He is a consultant for Sorrento, TILT Biotherapeutics, and Viewpoint Molecular Therapeutics. C.F. Lucchinetti may accrue revenue for a patent (no. 7101679) regarding aquaporin-4-associated antibodies for diagnosis of neuromyelitis optica and receives research support from the National MS Society, Biogen, and NIH. R. Mustafa has consulted with Horizon Therapeutics regarding educational content for neuromyelitis optica spectrum disorders and neurohospitalist practice. Dr. Mustafa serves as Treasurer and on the Board of Directors of the NeuroHospitalist Society and is an editorial board member of The Neurohospitalist. E.P. Flanagan has served on advisory boards for Alexion, Genentech, Horizon Therapeutics and UCB. He has received research support from UCB. He has received speaker honoraria from Pharmacy Times. He received royalties from UpToDate. Dr. Flanagan is a site principal investigator in a randomized clinical trial of Rozanolixizumab for relapsing myelin oligodendrocyte glycoprotein antibody-associated disease run by UCB. Dr. Flanagan is a site principal investigator and a member of the steering committee for a clinical trial of satralizumab for relapsing myelin oligodendrocyte glycoprotein antibody-associated disease run by Roche/Genentech. Dr. Flanagan has received funding from the NIH (R01NS113828). Dr. Flanagan is a member of the medical advisory board of the MOG project. Dr. Flanagan is an editorial board member of Neurology, Neuroimmunology and Neuroinflammation, The Journal of the Neurologic Sciences and Neuroimmunology Reports. A patent has been submitted on DACH1-IgG as a biomarker of paraneoplastic autoimmunity. Go to Neurology.org/NN for full disclosures.

Formato:Informe impreso

Idioma:Inglés

País de fuente:EE.UU.

Sitio web:http://dx.doi.org/10.1212/NXI.0000000000200249