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La Sociedad Iberoamericana de Información Científica (SIIC)
selecciona informes completos de calidad recientemente publicados en
fuentes prestigiosas del mundo indizadas por SIIC Data
Bases.
La creciente cantidad de artículos con Acceso Abierto (Open
Access) amplía la oferta de lectura pero a su vez también, entre
tanta abundancia, complica al lector en su encuentro con los estudios
fundamentales. Para facilitarlo, profesionales biomédicos de SIIC
consultan diariamente una profusa cantidad de documentos que nutrirán
Textos completos autorizados (TCA).
Las citas de la sección TCA enlazan de manera legal, autorizada y
gratuita con los textos completos (full text) publicados en
los sitios oficiales de sus respectivas fuentes.
SIIC creó, produjo y opera con exclusividad el software TCA para la
interpretación de los diversos campos documentales que integran la
estructura de un estudio: especialidad, modalidad del estudio,
fuente, fechas de publicación y selección, definición de la fuente,
limitaciones de consulta, resumen en castellano, etc.
Si bien la mayoría de los textos seleccionados corresponden a
artículos originales, revisiones y guías, los lectores también
encontrarán comentarios, entrevistas, notas periodísticas, cartas a
autores u otros textos precursores de debates o aclaratorios.
Sociedad Iberoamericana de Información Científica (SIIC) selects
complete quality-full texts which have been recently published in
renowned sources worldwide and are indexed by SIIC Data
Bases.
The increasing number of Open Access articles widens the reading offer
but, also, such myriad complicates the readers search of fundamental
articles. To facilitate this, SIIC biomedical professionals daily
consult a profuse amount of documents that will feed
Authorized Full Texts (TCA, Spanish acronym).
The citations of the AFT section link legally, authorized and free of
charge with the full texts published in the official web sites of
their corresponding sources.
SIIC created, produced and handles the AFT software that deciphers
the various documentary fields that form part of the structure of a
study: specialty, study style, source, publication and selection
dates, source definition, query limitations, summary in Spanish,
etc.
While most of the selected texts belong to original articles,
reviews, and guidelines, readers will also find commentaries,
interviews, journalistic reports, letters to authors or other texts
that may lead to discussions or clarifications.
Frailty and transplant-free survival of patients with liver cirrhosis
Frailty and transplant-free survival of patients with liver cirrhosis
Fuente:Plos One
Tipo de trabajo:Metanálisis
Extracto:
The evidence suggests that frailty may be an independent risk factor for poor TFS
in patients with liver cirrhosis, thus emphasizing the importance of early
identification and management of frailty in this population.
Cita:PLoS One 2024; 19 (5) : e0302836.
Autor/es:Yuan, Chunhui (a) Li, Weihua (b)
institución:(a) Department of Gastroenterology, Changsha Fourth Hospital, Changsha, Hunan Province, China. (b) Department of Gastroenterology, Changsha Fourth Hospital, Changsha, Hunan Province, China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Socioeconomic status and health disparities drive differences in accelerometer-derived physical activity in fatty liver disease and significant fibrosis.
Socioeconomic status and health disparities drive differences in accelerometer-derived physical activity in fatty liver disease and significant fibrosis.
Fuente:Plos One
Tipo de trabajo:Guía
Extracto:
These findings demonstrate the role of PA
as a protective factor against the presence of NAFLD and significant fibrosis.
Protective levels of PA in NAFLD differ by races.
Cita:PLoS One 2024; 19 (5) : e0301774.
Autor/es:Tabacu, Lucia (a) Swami, Sajag (b)
institución:(a) Dept. of Mathematics and Statistics, Norfolk, Virginia, United States of America. (b) Dept. of Mechanical and Industrial Engineering, Indian Institute of Technology Roorkee, Roorkee, India.
Conflicto:Conflicts of Interest: Dr. Mohammad Shadab Siddiqui: AMRA (Advisory Board), NovoNordisk (Consultant), Sagimet (Consult).
Population-level impact of the BMJ Rapid Recommendation for colorectal cancer screening: a microsimulation analysis.
Population-level impact of the BMJ Rapid Recommendation for colorectal cancer screening: a microsimulation analysis.
Fuente:Bmj Open Gastroenterology
Extracto:
With the recommended risk prediction tool, the
population impact of the BMJ Rapid Recommendation would be similar to screening
initiation based on age and sex only. It would delay screening initiation by
10-15 years. Although halving the screening burdens, screening benefits would be
reduced substantially compared with screening initiation at age 50. This suggests
that the 3% risk threshold to start CRC screening might be too high.
Claves:CANCER PREVENTION, COLORECTAL CANCER SCREENING, DECISION ANALYSIS, SCREENING
Cita:BMJ Open Gastroenterol 2024 May 9; 11 (1)
Autor/es:van Duuren, Luuk A (a) Bulliard, Jean-Luc (b)
institución:(a) Unisanté, Center for Primary Care and Public Health, University of Lausanne, Lausanne, Switzerland l.vanduuren@erasmusmc.nl. (b) Department of Public Health, Erasmus University Medical Center, Rotterdam, The Netherlands.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
The central executive network moderates the relationship between posttraumatic stress symptom severity and gastrointestinal related issues.
The central executive network moderates the relationship between posttraumatic stress symptom severity and gastrointestinal related issues.
Fuente:Scientific Reports
Extracto:
Our findings of higher rsFC within the CEN
moderating the magnitude of coincidence in PTS and GI symptom severity may
reflect the mitigating role of executive control processes in the putative stress
signaling mechanisms that contribute to gut dysbiosis.
Cita:Sci Rep 2024 May 10; 14 (1) : 10695.
Autor/es:Howard, Kia A (a) Ahmad, Salman S (b)
institución:(a) Department of Psychology, University of Miami, Coral Gables, FL, 33146, USA. (b) Department of Psychology, University of Miami, Coral Gables, FL, 33146, USA.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
The association between healthy eating index-2015 with anthropometric, cardiometabolic and hepatic indices among patients with non-alcoholic fatty liver disease.
The association between healthy eating index-2015 with anthropometric, cardiometabolic and hepatic indices among patients with non-alcoholic fatty liver disease.
Fuente:Bmc Gastroenterology
Tipo de trabajo:Estudio de cohortes
Extracto:
The present study demonstrated a correlation between
lower HEI-2015 scores and an increased risk of steatosis in men with NAFLD.
Moreover, our findings highlighted gender-related differences in NAFLD and
cardio-metabolic disorders.
Autor/es:Hosseini, Seyed Ahmad (a) Shayesteh, Ali Akbar (b)
institución:(a) Nutrition and Metabolic Disease Research Center, Clinical Sciences Research Institute, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran. (b) Alimentary Tract Research Center, Clinical Sciences Research Institute, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Human adenoviruses in children with gastroenteritis
Human adenoviruses in children with gastroenteritis
Fuente:Bmc Infectious Diseases
Tipo de trabajo:Revisión sistemática
Extracto:
This study provided valuable
insights into the importance of HAdVs in children with gastroenteritis,
especially in hospitalized and younger children. The results can be used in
future preventive measurements and the development of effective vaccines.
Claves:Children, Epidemiology, Gastroenteritis, Human adenoviruses, Pediatrics
Cita:BMC Infect Dis 2024 May 9; 24 (1) : 478.
Autor/es:Khales, Pegah (a) Razizadeh, Mohammad Hossein (b)
institución:(a) Department of Bacteriology and Virology, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran. (b) Department of Virology, School of Medicine, Iran University of Medical Sciences, Tehran, Iran.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
institución:(a) Department of Colorectal Disease, Intestinal Microenvironment Treatment Center, General Surgery of Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai, 200072, China. (b) Tongji University School of Medicine, Shanghai, 200072, China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Safety analysis of Oseltamivir and Baloxavir Marboxil after market approval: a pharmacovigilance study based on the FDA adverse event reporting system.
Safety analysis of Oseltamivir and Baloxavir Marboxil after market approval: a pharmacovigilance study based on the FDA adverse event reporting system.
Fuente:Bmc Infectious Diseases
Extracto:
Monitoring fulminant hepatitis during Oseltamivir treatment, especially in
patients with liver-related diseases, is crucial. Oseltamivir's potential to
induce abnormal behavior, especially in adolescents, necessitates special
attention. Baloxavir Marboxil, with lower hepatic toxicity, emerges as a
potential alternative for patients with liver diseases. During Baloxavir Marboxil
treatment, focused attention on the occurrence of rhabdomyolysis is advised,
necessitating timely monitoring of relevant indicators for those with clinical
manifestations. The comprehensive data aims to provide valuable insights for
clinicians and healthcare practitioners, facilitating an understanding of the
safety profiles of these influenza treatments in real-world scenarios.
Claves:Baloxavir Marboxil, Fulminant hepatitis, Oseltamivir, Rhabdomyolysis, Safety, Side effect
Cita:BMC Infect Dis 2024 May 9; 24 (1) : 446.
Autor/es:Li, Yunsong (a) Wang, Xiaoling (b)
institución:(a) Department of Pharmacy, Women and Children's Hospital, School of Medicine, Xiamen University, 10# Zhenhai Road, Xiamen, China. (b) Department of Pharmacy, Women and Children's Hospital, School of Medicine, Xiamen University, 10# Zhenhai Road, Xiamen, China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Correlation of alanine aminotransferase levels and a histological diagnosis of steatohepatitis with ultrasound-diagnosed metabolic-associated fatty liver disease in patients from a centre in Nigeria.
Correlation of alanine aminotransferase levels and a histological diagnosis of steatohepatitis with ultrasound-diagnosed metabolic-associated fatty liver disease in patients from a centre in Nigeria.
Fuente:Bmc Gastroenterology
Extracto:
NASH can occur in patients
with MAFLD, irrespective of alanine transaminase (ALT) levels, and ultrasound
grading of the severity of steatosis cannot accurately predict NASH. Liver biopsy
remains the investigation of choice.
institución:(a) Department of General Medicine, Frimley Health NHS Foundation Trust, Wexham Park Hospital, Slough, SL2 4HL, UK. odeyemiolawumi@gmail.com. (b) Department of Medicine, LAUTECH Teaching Hospital, Ogbomoso, Oyo State, Nigeria.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Gut microbiota, blood metabolites, and left ventricular diastolic dysfunction in US Hispanics/Latinos.
Gut microbiota, blood metabolites, and left ventricular diastolic dysfunction in US Hispanics/Latinos.
Fuente:Microbiome
Extracto:
In this
study of US Hispanics/Latinos, we identified multiple gut bacteria and related
metabolites linked to LVDD, suggesting their potential roles in this preclinical
HF entity. Video Abstract.
Claves:Blood metabolome, Gut dysbiosis, Hispanic/Latino individuals, Left ventricular diastolic dysfunction
Cita:Microbiome 2024 May 10; 12 (1) : 85.
Autor/es:Luo, Kai (a) Taryn, Alkis (b)
institución:(a) Department of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, NY, 10461, USA. (b) Department of Epidemiology, Human Genetics and Environmental Sciences, School of Public Health, University of Texas Health Science Center at Houston, Houston, TX, 77030, USA.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
institución:(a) Department of Radiation Therapy and Oncology, Shin Kong Wu Ho-Su Memorial Hospital, Taipei, Taiwan. (b) Institute of Veterinary Clinical Science, School of Veterinary Medicine, National Taiwan University, Taipei, Taiwan.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Identification of potential mediators of the relationship between body mass index and colorectal cancer: a Mendelian randomization analysis.
Identification of potential mediators of the relationship between body mass index and colorectal cancer: a Mendelian randomization analysis.
Fuente:International Journal of Epidemiology
Extracto:
The effect of BMI on CRC risk is
possibly partly mediated through plasma IGF1, whereas the attenuation of the
BMI-CRC association by smoking and PA may reflect confounding and shared
underlying mechanisms rather than mediation.
Claves:BMI, Body mass index, CRC, Mendelian randomization, colorectal cancer, mediation analysis, obesity
Cita:Int J Epidemiol 2024 Apr 11; 53 (3)
Autor/es:Bouras, Emmanouil (a) Gill, Dipender (b)
institución:(a) Department of Hygiene and Epidemiology, University of Ioannina School of Medicine, Ioannina, Greece. (b) Chief Scientific Advisor Office, Research and Early Development, Novo Nordisk, Copenhagen, Denmark.
Conflicto:I have read the Journal’s policy and the authors of this manuscript have the following competing interests: D.G. is employed part-time by Novo Nordisk. The remaining authors have no competing interests to declare.
Extracto:
The importance of
histopathological examination should be emphasized to establish the diagnosis in
the absence of signs in favor of a primary localization.
EEG functional connectivity as a Riemannian mediator: An application to malnutrition and cognition.
EEG functional connectivity as a Riemannian mediator: An application to malnutrition and cognition.
Fuente:Human Brain Mapping
Extracto:
Our methods offer a versatile framework
applicable to mediation studies encompassing matrix and Hermitian 3D tensor
mediators alongside scalar exposures and outcomes, facilitating comprehensive
analyses across diverse research domains.
Autor/es:Lopez Naranjo, Carlos (a) Razzaq, Fuleah Abdul (b)
institución:(a) The Clinical Hospital of Chengdu Brain Science Institute, MOE Key Lab for Neuroinformation, School of Life Science and Technology, University of Electronic Science and Technology of China, Chengdu, China. (b) The Clinical Hospital of Chengdu Brain Science Institute, MOE Key Lab for Neuroinformation, School of Life Science and Technology, University of Electronic Science and Technology of China, Chengdu, China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
A polygenic risk score for alcohol-associated cirrhosis among heavy drinkers with European ancestry.
A polygenic risk score for alcohol-associated cirrhosis among heavy drinkers with European ancestry.
Fuente:Hepatology Communications
Extracto:
PRSALC incorporates 20
single-nucleotide polymorphisms, predicts increased risk for ALC, and improves
risk stratification for ALC compared with the models that only include clinical
risk factors. This new score has the potential for early detection of heavy
drinking patients who are at high risk for ALC.
Cita:Hepatol Commun 2024 Jun 1; 8 (6)
Autor/es:Schwantes-An, Tae-Hwi (a) Whitfield, John B (b)
institución:(a) Department of Medical and Molecular Genetics, Indiana University School of Medicine, Indianapolis IN, USA. (b) Genetic Epidemiology, QIMR Berghofer Medical Research Institute, Queensland 4029, Australia.
Conflicto:Naga P. Chalasani has a number of consulting agreements with and research grants from the pharmaceutical industry, but they are not significantly or directly related to this paper. Munir Pirmohamed receives research funding from various organizations, including the MRC and NIHR. He has also received partnership funding for the following: MRC Clinical Pharmacology Training Scheme (co-funded by MRC and Roche,...
UCB, Eli Lilly and Novartis); a PhD studentship jointly funded by EPSRC and Astra Zeneca; and grant funding from Vistagen Therapeutics. He has also unrestricted educational grant support for the UK Pharmacogenetics and Stratified Medicine Network from Bristol-Myers Squibb and UCB. He has developed an HLA genotyping panel with MC Diagnostics but does not benefit financially from this. He is part of the IMI Consortium ARDAT (www.ardat.org). None of these funding sources were deployed in the undertaking of this study. Timothy R. Morgan has conducted clinical research with AbbVie, Genfit, Gilead, and Merck but none of these are related to this manuscript. Tae-Hwi Schwantes-An is a paid consultant for Target RWE. Guruprasad P. Aithal consults and advises Clinipace, Servier, Pfizer, GSK, AstraZeneca, DNDi, BenevolentAI, Abbott Product Operations AG, Albireo, PureTech and Merck. RB is on the speakers’ bureau for AbbVie. Samer Gawrieh consults for TransMedics and Pfizer and received grants from Zydus, Viking, and SonicIncytes. Paul S. Haber received grants from Woke Pharmaceuticals. S Masson consults and is on the speakers’ bureau for Norgine and is on the speakers’ bureau for Dr. Falk and Sandoz. Christophe Moreno consults and received grants from AbbVie and Gilead. He consults for Surrozen, Intercept, Echosens, Novartis, Bayer, and Astellas. Beat Müllhaupt consults and received grants from Gilead and consults for Ipsen. Pierre Nahon consults and received grants from AstraZeneca, Bristol-Myers Squibb, and Eisai. He consults for Ipsen and Roche. Eric Trépo received grants from Gilead and Julius Clinical.
Patient-focused drug development in primary sclerosing cholangitis: Insights on patient priorities and involvement in clinical trials.
Patient-focused drug development in primary sclerosing cholangitis: Insights on patient priorities and involvement in clinical trials.
Fuente:Hepatology Communications
Tipo de trabajo:Estudio clínico
Extracto:
Most patients with PSC report interest in participating in clinical
trials, but few have been asked to participate. Referral of patients with PSC by
their hepatologist/gastroenterologist to clinical trials and patient education on
trial participation are vital to closing the gap between trial interest and
participation. Pruritus may serve as a key indicator of patient interest in trial
participation.
Cita:Hepatol Commun 2024 Jun 1; 8 (6)
Autor/es:Li, Michael (a) Pai, Ruth-Anne (b)
institución:(a) Department of Medicine, Division of Gastroenterology and Hepatology, University of California, San Francisco, California, USA. (b) PSC Partners Seeking a Cure, Greenwood Village, Colorado, USA.
Conflicto:Christopher L. Bowlus received grants from Gilead, Bristol Myers Squibb, BiomX, Boston Scientific, COUR, CymaBay, GENFIT, GlaxoSmithKline, Mirum, Genkyotex, Intercept, Novartis, Pliant, and Target. Jennifer C. Lai consults for GENFIT. She advises Novo Nordisk. She received grants from Axcella and Pliant. The remaining authors have no conflicts to report.
Cetuximab plus FOLFOXIRI versus cetuximab plus FOLFOX as conversion regimen in RAS/BRAF wild-type patients with initially unresectable colorectal liver metastases (TRICE trial): A randomized controlled trial.
Cetuximab plus FOLFOXIRI versus cetuximab plus FOLFOX as conversion regimen in RAS/BRAF wild-type patients with initially unresectable colorectal liver metastases (TRICE trial): A randomized controlled trial.
Fuente:Plos Medicine
Tipo de trabajo:Estudio aleatorizado y controlado
Extracto:
The
combination of cetuximab with FOLFOXIRI did not significantly improve ORR
compared to cetuximab plus FOLFOX. Despite achieving an enhanced DpR, this
improvement did not translate into improved R0 resection rates or PFS. Moreover,
the triplet arm was associated with an increase in treatment-related toxicity.
TRIAL REGISTRATION: ClinicalTrials.gov Identifier: NCT03493048.
Cita:PLoS Med 2024 May; 21 (5) : e1004389.
Autor/es:Wang, De-Shen (a) Ren, Chao (b)
institución:(a) Department of Medical Oncology, State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Sun Yat-sen University Cancer Center, Guangzhou, China. (b) Department of Medical Oncology, State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Sun Yat-sen University Cancer Center, Guangzhou, China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Prevalence and factors associated with inappropriate continuation of stress ulcer prophylaxis at discharge.
Prevalence and factors associated with inappropriate continuation of stress ulcer prophylaxis at discharge.
Fuente:Bmj Open Quality
Extracto:
The prevalence of
inappropriate continuation was found to be higher than prior studies. Given the
risk of unnecessary medication intake and the associated healthcare cost, a
web-based quality improvement initiative is being considered.
Claves:Medication reconciliation, Patient safety, Patient-centred care, Safety culture
institución:(a) Internal Medicine, Michigan State University College of Human Medicine, East Lansing, Michigan, USA chinnapp@msu.edu. (b) Internal Medicine, Hurley Medical Center, Flint, Michigan, USA.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
A chain mediation model reveals the association between family sense of coherence and quality of life in caregivers of advanced cancer patients.
A chain mediation model reveals the association between family sense of coherence and quality of life in caregivers of advanced cancer patients.
Fuente:Scientific Reports
Extracto:
These insights enhance our
understanding of the complex interplay between FSOC and QoL, underscoring the
potential benefits of bolstering FSOC to strengthen caregiver resilience,
alleviate distress, and ultimately elevate their QoL.
Claves:Advanced cancer caregivers, Chain mediation, Family sense of coherence, Psychological distress, Psychological resilience, Quality of life
Cita:Sci Rep 2024 May 10; 14 (1) : 10701.
Autor/es:Cui, Panpan (a) Cheng, Chunyan (b)
institución:(a) Department of Nursing, Henan Provincial Key Medicine Laboratory of Nursing, Henan Provincial People's Hospital, Zhengzhou University People's Hospital, No. 7 Weiwu Road, Zhengzhou, China. (b) School of Nursing, Zhengzhou University, Zhengzhou, China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Early nutrition is safe and does not increase complications after upper gastrointestinal bleeding-a systematic review and meta-analysis of randomized controlled trials.
Early nutrition is safe and does not increase complications after upper gastrointestinal bleeding-a systematic review and meta-analysis of randomized controlled trials.
Fuente:Scientific Reports
Extracto:
In conclusion, compared with DN, EN (within 24 h) appears to
be a safe intervention and could reduce the length of hospital stay without
increasing the risk of complications after UGIB.
institución:(a) Centre for Translational Medicine, Semmelweis University, Budapest, 1085, Hungary. (b) Institute for Translational Medicine, Medical School, University of Pécs, Pécs, 7623, Hungary.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación