Olvidé mi contraseña
Asóciese a SIIC en Internet para utilizar sin límites tanto siicsalud como la totalidad de los servicios bibliográficos de la institución.
SIIC selecciona textos completos de calidad y de reciente publicación en fuentes prestigiosas del mundo
indizadas por SIIC Data Bases, capturadas en las mismas colecciones o en diversas bases especializadas.
La creciente cantidad de artículos con Acceso Abierto (Open
Access) amplía la oferta de lectura pero a su vez también, entre
tanta abundancia, complica al lector en su encuentro con los estudios
fundamentales. Para facilitarlo, profesionales biomédicos de SIIC
consultan diariamente una profusa cantidad de documentos que nutrirán
Textos completos autorizados (TCA).
Las citas de la sección TCA enlazan de manera legal, autorizada y
gratuita con los textos completos (full text) publicados en
los sitios oficiales de sus respectivas fuentes.
SIIC creó, produjo y opera con exclusividad el software TCA para la
interpretación de los diversos campos documentales que integran la
estructura de un estudio: especialidad, modalidad del estudio,
fuente, fechas de publicación y selección, definición de la fuente,
limitaciones de consulta, resumen en castellano, etc.
Si bien la mayoría de los textos seleccionados corresponden a
artículos originales, revisiones y guías, los lectores también
encontrarán comentarios, entrevistas, notas periodísticas, cartas a
autores u otros textos precursores de debates o aclaratorios.
Sociedad Iberoamericana de Información Científica (SIIC) selects
complete quality-full texts which have been recently published in
renowned sources worldwide and are indexed by SIIC Data
Bases.
The increasing number of Open Access articles widens the reading offer
but, also, such myriad complicates the readers search of fundamental
articles. To facilitate this, SIIC biomedical professionals daily
consult a profuse amount of documents that will feed
Authorized Full Texts (TCA, Spanish acronym).
The citations of the AFT section link legally, authorized and free of
charge with the full texts published in the official web sites of
their corresponding sources.
SIIC created, produced and handles the AFT software that deciphers
the various documentary fields that form part of the structure of a
study: specialty, study style, source, publication and selection
dates, source definition, query limitations, summary in Spanish,
etc.
While most of the selected texts belong to original articles,
reviews, and guidelines, readers will also find commentaries,
interviews, journalistic reports, letters to authors or other texts
that may lead to discussions or clarifications.
A prospective phase II clinical trial of total neoadjuvant therapy for locally advanced gastric cancer and gastroesophageal junction adenocarcinoma.
A prospective phase II clinical trial of total neoadjuvant therapy for locally advanced gastric cancer and gastroesophageal junction adenocarcinoma.
Fuente:Scientific Reports
Extracto:
The total neoadjuvant therapy comprising NCRT
followed by NCCT and surgery demonstrates a low severe adverse reactions and
promising efficacy, which could be considered as a viable treatment for locally
advanced GC or GEJ adenocarcinoma.Trial registration: Clinicaltrials.gov
(registration number: NCT04062058); the full date of first trial registration was
20/08/2019.
institución:(a) Department of Radiation Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100021, China. (b) Department of Radiation Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100021, China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Abdominal abscess caused by Raoultella ornithinolytica secondary to postoperative gastric fistula
Abdominal abscess caused by Raoultella ornithinolytica secondary to postoperative gastric fistula
Fuente:Bmc Infectious Diseases
Tipo de trabajo:Revisión
Extracto:
To the best of our knowledge, case of isolating R.
ornithinolytica from a patient with non-viscerally abdominal abscess was
extremely rare. We share a case of a woman with non-viscerally abdominal abscess
secondary to postoperative gastric fistula, R. ornithinolytica was isolated from
the patient's pus, and the pathogenic bacteria may originate from the
gastrointestinal tract. Based on this case, We should be cautious that invasive
treatment may greatly increase the probability of infection with this pathogenic
bacterium.
institución:(a) The Central Hospital of Shaoyang, Shaoyang, Hunan, China. 2374720832@qq.com. (b) The Central Hospital of Shaoyang, Shaoyang, Hunan, China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Single-nucleotide polymorphism in CYP1A1, CYP1B1, CYP2B6, CYP2C8, and CYP2C9 genes and their association with gastrointestinal cancer: A hospital-based case-control study.
Single-nucleotide polymorphism in CYP1A1, CYP1B1, CYP2B6, CYP2C8, and CYP2C9 genes and their association with gastrointestinal cancer: A hospital-based case-control study.
Fuente:Journal of Cancer Research and Therapeutics
Extracto:
The findings from this
study supported that polymorphism of CYP2B6*5gene may be involved in the
development of GI cancer. However, other SNPs of CYP1A, CYP1B, and CYP2C genes
did not signify the risk for GI cancer in the studied population of rural
Maharashtra.
Cita:J Cancer Res Ther 2024 Jan 1; 20 (1) : 216-223.
Autor/es:Patil, Madhavi N (a) Datkhile, Kailas D (b)
institución:(a) Department of Molecular Biology and Genetics, Krishna Institute of Medical Sciences "Deemed to be University", Satara, Maharashtra, India. (b) Department of Molecular Biology and Genetics, Krishna Institute of Medical Sciences "Deemed to be University", Satara, Maharashtra, India.
Naples prognostic score may predict overall survival in metastatic pancreatic cancer.
Naples prognostic score may predict overall survival in metastatic pancreatic cancer.
Fuente:Journal of Cancer Research and Therapeutics
Extracto:
NPS may be a useful prognostic marker for the prediction of OS in
metastatic PC patients receiving systemic chemotherapy.
Cita:J Cancer Res Ther 2024 Jan 1; 20 (1) : 249-254.
Autor/es:Gulturk, Ilkay (a) Yilmaz, Mesut (b)
institución:(a) Medical Oncology Department, Bakirkoy Dr. Sadi Konuk Training and Research Hospital, Istanbul, Turkey. (b) Medical Oncology Department, Bakirkoy Dr. Sadi Konuk Training and Research Hospital, Istanbul, Turkey.
Methylation study of tumor suppressor genes in human aberrant crypt foci, colorectal carcinomas, and normal colon.
Methylation study of tumor suppressor genes in human aberrant crypt foci, colorectal carcinomas, and normal colon.
Fuente:Journal of Cancer Research and Therapeutics
Extracto:
Early epigenetic methylation of WIF1 gene is one of the mechanisms
for ACF development in human colon.
Cita:J Cancer Res Ther 2024 Jan 1; 20 (1) : 268-274.
Autor/es:Sarangi, Jayati (a) Das, Prasenjit (b)
institución:(a) Department of Pathology, All India Institute of Medical Sciences, New Delhi, India. (b) Department of Pathology, All India Institute of Medical Sciences, New Delhi, India.
Clinicopathological and prognostic significance of VEGF, PDGF-B, and HER2/neu expression in gallbladder cancer.
Clinicopathological and prognostic significance of VEGF, PDGF-B, and HER2/neu expression in gallbladder cancer.
Fuente:Journal of Cancer Research and Therapeutics
Extracto:
Overexpression of VEGF, PDGF-B, and
HER2/neu might be possible prognostic biomarkers in GBC. Poor survival of VEGF
and HER2/neu positive cases indicates the possibilities of using their blockers
as therapeutic agents.
Cita:J Cancer Res Ther 2024 Jan 1; 20 (1) : 349-357.
Autor/es:Shukla, Pooja (a) Mishra, Kumudesh (b)
institución:(a) Department of Translational Molecular Pathology, MD Anderson Cancer Center, Houston, TX, USA. (b) Department of Neurology, Faculty of Medicine, Hadassah-Hebrew University Medical Center, Ein Kerem, Jerusalem, Israel.
Comparison of clinical outcomes of robotic-assisted and video-assisted esophagectomy for esophageal cancer.
Comparison of clinical outcomes of robotic-assisted and video-assisted esophagectomy for esophageal cancer.
Fuente:Journal of Cancer Research and Therapeutics
Extracto:
Robotic procedures can be safely
performed in esophageal cancers with complication rates and oncological
radicality similar to those of other minimally invasive techniques.
Cita:J Cancer Res Ther 2024 Jan 1; 20 (1) : 410-416.
Autor/es:Yüksel, Sercan (a) Topal, Uğur (b)
institución:(a) Department of General Surgery, Başakşehir Çam and Sakura City Hospital, Başakşehir, Istanbul, Turkey. (b) Department of Surgical Oncology, Başakşehir Çam and Sakura City Hospital, Başakşehir, Istanbul, Turkey.
Extranodal follicular dendritic cell sarcoma presenting as colonic mass: A diagnostic and therapeutic challenge.
Extranodal follicular dendritic cell sarcoma presenting as colonic mass: A diagnostic and therapeutic challenge.
Fuente:Journal of Cancer Research and Therapeutics
Extracto:
Herein we report, two cases of
extranodal FDCS of colon with the aim of contributing to the management of this
uncommon entity.
Cita:J Cancer Res Ther 2024 Jan 1; 20 (1) : 450-453.
Autor/es:Pasricha, Sunil (a) Durga, Garima (b)
institución:(a) Department of Pathology, Rajiv Gandhi Cancer Institute and Research Center, New Delhi, India. (b) Department of Pathology, Rajiv Gandhi Cancer Institute and Research Center, New Delhi, India.
Annals of the Royal College of Surgeons of England
Selección SIIC: 4 Abril, 2024
Annals of the Royal College of Surgeons of England
Redefining clinical practice through spatial profiling: a revolution in tissue analysis.
Redefining clinical practice through spatial profiling: a revolution in tissue analysis.
Fuente:Annals of The Royal College of Surgeons of England
Extracto:
In this paper, we discuss the recent evolution of spatial
biology, and its potential for improving our tissue level understanding and
treatment of disease, to help advance precision and effectiveness in healthcare
interventions.
Clinical Analysis and in Vitro Correlation of BCRP-Mediated Drug-Drug Interaction in the Gastrointestinal Tract.
Clinical Analysis and in Vitro Correlation of BCRP-Mediated Drug-Drug Interaction in the Gastrointestinal Tract.
Fuente:Biological & Pharmaceutical Bulletin
Extracto:
Therefore, it is suggested that the in vitro study using Caco-2 cells
could be used to quantitatively estimate BCRP-mediated DDI with ROS in the
gastrointestinal tract.
Claves:Caco-2, absorption rate constant (ka), breast cancer resistance protein, cell to medium ratio, drug–drug interaction, rosuvastatin
institución:(a) Laboratory of Biopharmaceutics, Department of Pharmacology, Faculty of Pharmacy, Takasaki University of Health and Welfare. (b) Laboratory of Biopharmaceutics, Department of Pharmacology, Faculty of Pharmacy, Takasaki University of Health and Welfare.
U-Shaped Association between Serum Chloride Levels and In-Hospital Mortality in Patients with Congestive Heart Failure in Intensive Care Units.
U-Shaped Association between Serum Chloride Levels and In-Hospital Mortality in Patients with Congestive Heart Failure in Intensive Care Units.
Fuente:International Heart Journal
Extracto:
Stratified analyses demonstrated the robustness of
this correlation.The relationship between serum chloride levels and in-hospital
mortality in patients with heart failure was U-shaped, with an inflection point of
105.017 mmol/L.
Intravenous metoclopramide for increasing endoscopic mucosal visualization in patients with acute upper gastrointestinal bleeding: a multicenter, randomized, double-blind, controlled trial.
Intravenous metoclopramide for increasing endoscopic mucosal visualization in patients with acute upper gastrointestinal bleeding: a multicenter, randomized, double-blind, controlled trial.
Fuente:Scientific Reports
Tipo de trabajo:Estudio clínico
Extracto:
Pre-endoscopic intravenous metoclopramide
improved the quality of EMV in variceal etiologies of UGIH, which was especially
prominent in those who had signs of active bleeding based on nasogastric tube
assessment.Trial Registration: Trial was registered in Clinical Trials: TCTR
20210708004 (08/07/2021).
institución:(a) Division of Gastroenterology and Hepatology, Department of Medicine, Faculty of Medicine, Vajira Hospital, Navamindradhiraj University, 681 Samsen Road, Dusit District, Bangkok, 10300, Thailand. (b) Division of Gastroenterology, Phra Nakhon Si Ayutthaya Hospital, Ayutthaya, Thailand.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
CAF-associated genes putatively representing distinct prognosis by in silico landscape of stromal components of colon cancer.
CAF-associated genes putatively representing distinct prognosis by in silico landscape of stromal components of colon cancer.
Fuente:Plos One
Extracto:
Our current in silico
analysis of the micro-dissected stromal gene signatures with prognostic relevance
clarified comprehensive understanding of clinical features of the TME and
provides deep insights of the landscape.
Cita:PLoS One 2024; 19 (4) : e0299827.
Autor/es:Okuno, Kota (a) Ikemura, Kyonosuke (b)
institución:(a) Division of Advanced Surgical Oncology, Research and Development Center for New Medical Frontiers, Kitasato University School of Medicine, Sagamihara, Japan. (b) Division of Advanced Surgical Oncology, Research and Development Center for New Medical Frontiers, Kitasato University School of Medicine, Sagamihara, Japan.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Association of per- and polyfluoroalkyl substances with constipation: The National Health and Nutrition Examination Survey (2005-2010).
Association of per- and polyfluoroalkyl substances with constipation: The National Health and Nutrition Examination Survey (2005-2010).
Fuente:Plos One
Extracto:
The
findings of this study provide evidence of a significant inverse correlation
between serum concentrations of PFAS, particularly PFOA and PFHxS, and
constipation.
Cita:PLoS One 2024; 19 (4) : e0301129.
Autor/es:Zhao, Yifan (a) Pu, Ke (b)
institución:(a) The First Clinical Medical College, Lanzhou University, Lanzhou, China. (b) Department of Gastroenterology, The First Hospital of Lanzhou University, Lanzhou, China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Targeting the gut microbiota to enhance the antitumor efficacy and attenuate the toxicity of CAR-T cell therapy: a new hope?
Targeting the gut microbiota to enhance the antitumor efficacy and attenuate the toxicity of CAR-T cell therapy: a new hope?
Fuente:Frontiers in Immunology
Extracto:
Above all, we highlight potential strategies
and challenges in harnessing the gut microbiota as a predictor and modifier of
CAR-T cell therapy efficacy while attenuating toxicity.
Claves:CAR-T cell therapy, antitumor efficacy, gut microbiota, immunotherapy, toxicity
Cita:Front Immunol 2024; 15 : 1362133.
Autor/es:Zhang, Peng-Fei (a) Xie, Dan (b)
institución:(a) Gastric Cancer Center, Division of Medical Oncology, Cancer Center, West China Hospital, Sichuan University, Chengdu, China. (b) Department of Medical Genetics, West China Second University Hospital, Sichuan University, Chengdu, China.
Conflicto:The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
Rapid identification of inflammatory arthritis and associated adverse events following immune checkpoint therapy: a machine learning approach.
Rapid identification of inflammatory arthritis and associated adverse events following immune checkpoint therapy: a machine learning approach.
Fuente:Frontiers in Immunology
Extracto:
Patients with ICI-IA were significantly more likely
to also develop cutaneous, endocrine, and gastrointestinal irAEs during their
clinical course compared to ICI therapy patients without ICI-IA.
institución:(a) Center for Health Information Partnerships, Northwestern University Feinberg School of Medicine, Chicago, IL, United States. (b) Feinberg School of Medicine, Northwestern University, Chicago, IL, United States.
Conflicto:TLW receives unrelated research funding from Gilead Sciences. AK is a strategic advisor for Datavant, Inc. The remaining authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
Intestinal microbiota and biliary system diseases.
Intestinal microbiota and biliary system diseases.
Fuente:Frontiers in Cellular and Infection Microbiology
Tipo de trabajo:Revisión
Extracto:
We hope to provide biomarkers
forearly diagnosis of biliary system diseases and provide new directions for the
mechanism of intestinal microbiota in biliary diseases.
institución:(a) Department of Health, The Chinese People's Armed Police Forces Anhui Provincial Corps Hospital, Hefei, China. (b) Department of General Surgery, The Chinese People's Armed Police Forces Anhui Provincial Corps Hospital, Hefei, China.
Conflicto:The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
The causal relationship between gut microbiota and biliary tract cancer: comprehensive bidirectional Mendelian randomization analysis.
The causal relationship between gut microbiota and biliary tract cancer: comprehensive bidirectional Mendelian randomization analysis.
Fuente:Frontiers in Cellular and Infection Microbiology
Extracto:
This investigation represents the inaugural
identification of indicative data supporting either beneficial or detrimental
causal relationships between gut microbiota and the risk of BTC, as determined
through the utilization of MR methodologies. These outcomes could hold
significance for the formulation of individualized therapeutic strategies aimed
at BTC prevention and survival enhancement.
Claves:biliary tract cancer, comprehensive bidirectional mendelian randomization, genome-wide association study, gut microbiota, probiotics
institución:(a) Department of Gastroenterology, Ruijin Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China. (b) Department of Gastroenterology, The Affiliated Hospital of Kunming University of Science and Technology, The First People's Hospital of Yunnan Province, Kunming, China.
Conflicto:The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
A multicenter clinical epidemiology of pediatric pneumococcal meningitis in China: results from the Chinese Pediatric Bacterial Meningitis Surveillance (CPBMS) 2019-2020.
A multicenter clinical epidemiology of pediatric pneumococcal meningitis in China: results from the Chinese Pediatric Bacterial Meningitis Surveillance (CPBMS) 2019-2020.
Fuente:Frontiers in Cellular and Infection Microbiology
Extracto:
Pediatric PM is more common in children
aged 3 months to < 3 years old. Intracranial complications mostly occur in
children < 1 year of age with fever being the most common clinical manifestations
and subdural effusion and (or) empyema and hydrocephalus being the most common
complications, respectively. CSF non-culture methods can facilitate improving the
detection rate of pathogenic bacteria. More than 10% of PM children had adverse
outcomes. S. pneumoniae strains are susceptible to vancomycin, linezolid,
ertapenem, levofloxacin, moxifloxacin, rifampicin, and chloramphenicol.
institución:(a) Department of Infectious Disease, Children's Hospital, Zhejiang University School of Medicine, National Clinical Research Center for Child Health, National Children's Regional Medical Center, Hangzhou, Zhejiang, China. (b) Department of Infectious Disease, Children's Hospital of Chongqing Medical University, Chongqing, China.
Conflicto:The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
Targeted multispectral filter array design for the optimization of endoscopic cancer detection in the gastrointestinal tract.
Targeted multispectral filter array design for the optimization of endoscopic cancer detection in the gastrointestinal tract.
Fuente:Journal of Biomedical Optics
Tipo de trabajo:Estudio clínico
Extracto:
The ability to retain good
classification accuracies with a reduced number of spectral bands could enable
the future deployment of multispectral imaging in an endoscopic chip-on-tip
configuration using simplified MSFA hardware. Further studies using an expanded
clinical dataset are needed to confirm these findings.
Autor/es:Taylor-Williams, Michaela (a) Tao, Ran (b)
institución:(a) University of Cambridge, Department of Physics, Cavendish Laboratory, Cambridge, United Kingdom. (b) University of Cambridge, Cancer Research UK Cambridge Institute, Cambridge, United Kingdom.