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La Sociedad Iberoamericana de Información Científica (SIIC)
selecciona informes completos de calidad recientemente publicados en
fuentes prestigiosas del mundo indizadas por SIIC Data
Bases.
La creciente cantidad de artículos con Acceso Abierto (Open
Access) amplía la oferta de lectura pero a su vez también, entre
tanta abundancia, complica al lector en su encuentro con los estudios
fundamentales. Para facilitarlo, profesionales biomédicos de SIIC
consultan diariamente una profusa cantidad de documentos que nutrirán
Textos completos autorizados (TCA).
Las citas de la sección TCA enlazan de manera legal, autorizada y
gratuita con los textos completos (full text) publicados en
los sitios oficiales de sus respectivas fuentes.
SIIC creó, produjo y opera con exclusividad el software TCA para la
interpretación de los diversos campos documentales que integran la
estructura de un estudio: especialidad, modalidad del estudio,
fuente, fechas de publicación y selección, definición de la fuente,
limitaciones de consulta, resumen en castellano, etc.
Si bien la mayoría de los textos seleccionados corresponden a
artículos originales, revisiones y guías, los lectores también
encontrarán comentarios, entrevistas, notas periodísticas, cartas a
autores u otros textos precursores de debates o aclaratorios.
Sociedad Iberoamericana de Información Científica (SIIC) selects
complete quality-full texts which have been recently published in
renowned sources worldwide and are indexed by SIIC Data
Bases.
The increasing number of Open Access articles widens the reading offer
but, also, such myriad complicates the readers search of fundamental
articles. To facilitate this, SIIC biomedical professionals daily
consult a profuse amount of documents that will feed
Authorized Full Texts (TCA, Spanish acronym).
The citations of the AFT section link legally, authorized and free of
charge with the full texts published in the official web sites of
their corresponding sources.
SIIC created, produced and handles the AFT software that deciphers
the various documentary fields that form part of the structure of a
study: specialty, study style, source, publication and selection
dates, source definition, query limitations, summary in Spanish,
etc.
While most of the selected texts belong to original articles,
reviews, and guidelines, readers will also find commentaries,
interviews, journalistic reports, letters to authors or other texts
that may lead to discussions or clarifications.
EULAR recommendations for the treatment of systemic sclerosis: 2023 update.
EULAR recommendations for the treatment of systemic sclerosis: 2023 update.
Fuente:Annals of The Rheumatic Diseases
Tipo de trabajo:Revisión
Extracto:
These updated recommendations include the first set of synthetic and biological
targeted therapies recommended for key fibrotic manifestations of SSc as well as
first-line combination treatment for newly diagnosed pulmonary artery
hypertension and prioritise a new research agenda for the coming years.
Autor/es:Del Galdo, Francesco (a) Lescoat, Alain (b)
institución:(a) Leeds Institute of Rheumatic and Musculoskeletal Medicine, LIRMM, Leeds, UK; NIHR Leeds Biomedical Research Centre, Leeds Teaching Hospitals Trust, Leeds, UK. Electronic address: f.delgaldo@leeds.ac.uk. (b) Department of Internal Medicine and Clinical Immunology, Rennes University Hospital, Rennes, France.
Lupus and inflammatory bowel disease share a common set of microbiome features distinct from other autoimmune disorders.
Lupus and inflammatory bowel disease share a common set of microbiome features distinct from other autoimmune disorders.
Fuente:Annals of The Rheumatic Diseases
Extracto:
Our findings underscore the gut microbiome's critical
role in autoimmune diseases, offering insights into shared and distinct microbial
signatures. The study highlights the potential importance of microbial biomarkers
in understanding disease mechanisms and guiding treatment strategies, paving the
way for novel therapeutic approaches based on microbial profiles. TRIAL
REGISTRATION NUMBER: NCT02394964.
institución:(a) Meinig School of Biomedical Engineering, Cornell University, Ithaca, New York, USA. (b) Meinig School of Biomedical Engineering, Cornell University, Ithaca, New York, USA.
institución:(a) Institute of Infection, Veterinary & Ecological Sciences, University of Liverpool, Liverpool, United Kingdom. (b) Institute of Infection, Veterinary & Ecological Sciences, University of Liverpool, Liverpool, United Kingdom.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Development and validation of an integrated model for the diagnosis of liver cirrhosis with portal vein thrombosis combined with endoscopic characters and blood biochemistry data
Development and validation of an integrated model for the diagnosis of liver cirrhosis with portal vein thrombosis combined with endoscopic characters and blood biochemistry data
Fuente:Annals of Medicine
Tipo de trabajo:Estudio de cohortes
Extracto:
Blood test combined endoscopic
characters could preliminarily predict the liver cirrhosis with portal vein
thrombosis for cirrhotic patients undergoing endoscopic examination.
Claves:Liver cirrhosis, endoscopic, portal vein thrombosis, prediction model
Cita:Ann Med 2025 Dec; 57 (1) : 2457521.
Autor/es:Yang, Jie (a) Zhang, Xu (b)
institución:(a) Endoscopic Diagnosis and Treatment Center, Gansu Provincial Hospital, Lanzhou, Gansu, China. (b) Endoscopic Diagnosis and Treatment Center, Gansu Provincial Hospital, Lanzhou, Gansu, China.
Conflicto:No conflict of interest was reported by the authors.
Differences in the intrahepatic expression of immune checkpoint molecules on T cells and natural killer cells in chronic HBV patients.
Differences in the intrahepatic expression of immune checkpoint molecules on T cells and natural killer cells in chronic HBV patients.
Fuente:Frontiers in Immunology
Extracto:
Our study shows clear differences in the intrahepatic
expression of ICMs on NK cells and T cells in chronic HBV patients depending on
their clinical stage.
Claves:4-1BB, HBV, NK cells, PD-1, T cells, immune checkpoint molecules, liver
institución:(a) Univ. Grenoble Alpes, Inserm U 1209, CNRS UMR 5309, Institute for Advanced Biosciences, Grenoble, France. (b) Univ. Grenoble Alpes, Inserm U 1209, CNRS UMR 5309, Institute for Advanced Biosciences, Grenoble, France.
Conflicto:The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
Randomized controlled trials of digital health interventions for rheumatic disease management
Randomized controlled trials of digital health interventions for rheumatic disease management
Fuente:Bulletin of The World Health Organization
Tipo de trabajo:Revisión sistemática
Extracto:
Digital health
interventions show promise for managing rheumatic diseases. Tailoring these
interventions to local infrastructure and emphasizing patient engagement are
crucial for successful adoption. Future research should focus on standardizing
evaluation methods, addressing digital divides and enhancing provider support and
data services.
Cita:Bull World Health Organ 2025 Feb 1; 103 (2) : 136-147.
Autor/es:Santosa, Anindita (a) Li, James Weiquan (b)
institución:(a) Aaria Rheumatology, 6 Napier Road 08-19, Gleneagles Medical Centre, Singapore258499, Singapore. (b) Department of Gastroenterology and Hepatology, Changi General Hospital, Singapore.
Automatic Quality Control System and Adenoma Detection Rates During Routine Colonoscopy
Automatic Quality Control System and Adenoma Detection Rates During Routine Colonoscopy
Fuente:Jama Network Open
Tipo de trabajo:Estudio clínico aleatorizado
Extracto:
AND RELEVANCE: In this
randomized clinical trial, AQCS assistance during routine colonoscopy increased
adenoma detection rates and several related polyp parameters compared with
standard colonoscopy in the lower- and medium-level detectors in academic and
nonacademic settings. Routine use of AQCS to assist in colorectal adenoma
detection and quality improvement should be considered. TRIAL REGISTRATION:
ClinicalTrials.gov Identifier: NCT04901130.
Cita:JAMA Netw Open 2025 Jan 2; 8 (1) : e2457241.
Autor/es:Liu, Jing (a) Zhou, Ruchen (b)
institución:(a) Department of Gastroenterology, Qilu Hospital of Shandong University, Jinan, Shandong, China. (b) Shandong Provincial Clinical Research Center for Digestive Disease, Jinan, Shandong, China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Immune-related adverse events in older adults receiving immune checkpoint inhibitors: a comprehensive analysis of the Food and Drug Administration Adverse Event Reporting System.
Immune-related adverse events in older adults receiving immune checkpoint inhibitors: a comprehensive analysis of the Food and Drug Administration Adverse Event Reporting System.
Fuente:Age and Ageing
Tipo de trabajo:Estudio clínico
Extracto:
We discuss the potential changes in the
immune system contributing to the decreased prevalence of irAEs in the oldest age
group. Additionally, conservative treatment approaches and underreporting of
irAEs in older patients may influence these findings. Our findings highlight the
need for personalised decision-making for ICI therapies, considering performance
status and comorbidities rather than age alone.
Claves:Food and Drug Administration Adverse Event Reporting System (FAERS), adverse event, immune checkpoint inhibitors, older adults, older people, pharmacovigilance
Cita:Age Ageing 2025 Jan 6; 54 (1)
Autor/es:Esen, Buğra Han (a) Bektas, Sevval Nur (b)
institución:(a) School of Medicine, Koç University, Rumelifeneri Yolu 34450 Sarıyer, Istanbul, Turkey. (b) School of Medicine, Koç University, Rumelifeneri Yolu 34450 Sarıyer, Istanbul, Turkey.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Patient outcomes and health care resource utilization in acute pancreatitis-related central nervous system complications
Patient outcomes and health care resource utilization in acute pancreatitis-related central nervous system complications
Fuente:The Journal of International Medical Research
Tipo de trabajo:Estudio de cohortes
Extracto:
Patients with AP who develop CE face worse
outcomes, including increased mortality risk, prolonged hospital stay, and
greater resource utilization. Timely identification and effective management of
CE in AP may reduce mortality and ease the health care burden associated with
this neurological complication.
Claves:Pancreatitis, blood–brain disruption, caregiver burden, central nervous system, cerebral edema, health care resource utilization, intracranial pressure, pancreatic encephalopathy
Cita:J Int Med Res 2025 Jan; 53 (1) : 3000605241311405.
Autor/es:Shahzil, Muhammad (a) Chaudhary, Ammad Javaid (b)
institución:(a) Department of Internal Medicine, Penn State Health, Milton S Hershey Medical Center, The Pennsylvania State University, Hershey, PA, United States. (b) Department of Internal Medicine, Henry Ford Hospital, Detroit, MI, United States.
Conflicto:Declaration of conflicting interestThe authors declare that there is no conflict of interest.
Risk Factors for Gastrointestinal Bleeding in Patients With Acute Myocardial Infarction
Risk Factors for Gastrointestinal Bleeding in Patients With Acute Myocardial Infarction
Fuente:Journal of Medical Internet Research
Tipo de trabajo:Estudio de cohortes
Extracto:
The
ML-based RF model provides a robust and clinically applicable tool for predicting
in-hospital GIB in patients with AMI. By leveraging routinely available clinical
and laboratory data, the model supports early risk stratification and
personalized preventive strategies.
Claves:acute myocardial infarction, gastrointestinal bleeding, in-hospital, machine learning, prediction model
Cita:J Med Internet Res 2025 Jan 30; 27 : e67346.
Autor/es:Kou, Yanqi (a) Ye, Shicai (b)
institución:(a) Department of Gastroenterology, Affiliated Hospital of Guangdong Medical University, Zhanjiang, China. (b) Department of Gastroenterology, Affiliated Hospital of Guangdong Medical University, Zhanjiang, China.
Impact of introducing transnasal endoscopy on expanding diagnostic endoscopy services.
Impact of introducing transnasal endoscopy on expanding diagnostic endoscopy services.
Fuente:Bmj Open Quality
Extracto:
TNE is an emerging endoscopic modality, which
shows great promise in replacing TOE in most diagnostic circumstances. In a
modern healthcare service, TNE is cheaper, better tolerated and outperforms TOE
in multiple domains.
Successful Endoscopic Management of Oxyntic Gland Adenoma
Successful Endoscopic Management of Oxyntic Gland Adenoma
Fuente:Journal of Investigative Medicine High Impact Case Reports
Tipo de trabajo:Caso clínico
Extracto:
In this case, we are reporting a 22-year-old woman who
was diagnosed with OGA during evaluation of iron deficiency anemia and underwent
successful endoscopic resection.
Claves:gastric adenocarcinoma of fundic gland type (GA-FG), gastric adenocarcinoma with chief cell differentiation (GA-CCD), gastric adenoma, gastric polyp, oxyntic gland adenoma
Cita:J Investig Med High Impact Case Rep 2025 Jan-Dec; 13 : 23247096251313729.
institución:(a) Fresno Veterans Affairs Medical Center, CA, USA. (b) Staten Island University Hospital, NY, USA.
Conflicto:Declaration of Conflicting InterestsThe author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.
Cita:J Investig Med High Impact Case Rep 2025 Jan-Dec; 13 : 23247096251313734.
Autor/es:Jradi, Ahmad (a) Khoury, Kaline Maya (b)
institución:(a) University of Balamand, Beirut, Lebanon. (b) University of Balamand, Beirut, Lebanon.
Conflicto:Declaration of Conflicting InterestsThe author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.
Metagenomic global survey and in-depth genomic analyses of Ruminococcus gnavus reveal differences across host lifestyle and health status.
Metagenomic global survey and in-depth genomic analyses of Ruminococcus gnavus reveal differences across host lifestyle and health status.
Fuente:Nature Communications
Extracto:
gnavus.
Cita:Nat Commun 2025 Jan 30; 16 (1) : 1182.
Autor/es:Nooij, S (a) Plomp, N (b)
institución:(a) Leiden University Center for Infectious Diseases (LUCID), Leiden University Medical Center, Leiden, The Netherlands. (b) Center for Microbiome Analyses and Therapeutics, Leiden University Medical Center, Leiden, The Netherlands.
Conflicto:Competing interests: JN is an employee of Vedanta Biosciences Inc. The other authors report no competing interests.
Tofacitinib and budesonide treatment affect stemness and chemokine release in IBD patient-derived colonoids.
Tofacitinib and budesonide treatment affect stemness and chemokine release in IBD patient-derived colonoids.
Fuente:Scientific Reports
Extracto:
Our study demonstrates the value of employing human
colonoids to investigate how IBD drugs affect intestinal epithelial cells and
inter-individual variations relevant to mucosal healing and personalized IBD
treatment.
institución:(a) Department of Clinical and Molecular Medicine (IKOM), Faculty of Medicine and Health Sciences, NTNU - Norwegian University of Science and Technology, Prinsesse Kristinas gt. 1, Trondheim, 7030, Norway. (b) Department of Gastroenterology and Hepatology, Clinic of Medicine, St. Olav's University Hospital, Trondheim, Norway.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Autor/es:Simon, Orsolya Anna (a) Frim, Levente (b)
institución:(a) First Department of Medicine, Medical School, University of Pécs, Ifjúság Útja 13, 7624, Pécs, Hungary. simon.orsolya@pte.hu. (b) Institute for Translational Medicine, Medical School, University of Pécs, Pécs, Hungary. simon.orsolya@pte.hu.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
institución:(a) Division of Dengue Hemorrhagic Fever Research, Research Department, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand. (b) Siriraj Center of Research Excellence in Dengue and Emerging Pathogens, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Identification of novel serum lipid metabolism potential markers and metabolic pathways for oral cancer: a population-based study.
Identification of novel serum lipid metabolism potential markers and metabolic pathways for oral cancer: a population-based study.
Fuente:Bmc Cancer
Extracto:
Lipid metabolic
biomarkers identified in this study exhibit potential as candidate biomarkers for
OC diagnosis. Further validation through prospective studies is required to
confirm their clinical utility in early detection.
institución:(a) Department of Epidemiology and Health Statistics, Fujian Provincial Key Laboratory of Environment Factors and Cancer, School of Public Health, Fujian Medical University, 1 Xueyuan Road, Fujian, 350108, China. (b) Key Laboratory of Ministry of Education for Gastrointestinal Cancer, Fujian Medical University, Fujian, China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Allograft tolerance after adult living donor liver transplantation: a case-control study.
Allograft tolerance after adult living donor liver transplantation: a case-control study.
Fuente:Bmc Surgery
Extracto:
Allograft tolerance occurred in 74.7% of this cohort. We suggest that
the MELD score, indication for LT, ACR, recurrent viral hepatitis, and biliary
complications are predictors of allograft tolerance after LDLT.
Autor/es:Habl, Mohamed S (a) Emara, Moataz Maher (b)
institución:(a) Department of Hepatology and Gastroenterology, Faculty of Medicine, Mansoura University, Mansoura, Egypt. (b) Department of Anesthesiology and Intensive Care and Pain Medicine, Faculty of Medicine, Mansoura University, Mansoura, Egypt.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación