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Hungarian general practice paediatricians' antibiotic prescribing behaviour for suspected respiratory tract infections: a qualitative study.
Hungarian general practice paediatricians' antibiotic prescribing behaviour for suspected respiratory tract infections: a qualitative study.
Fuente:Bmj Open
Extracto:
Our findings suggest that a more prudent attitude toward antibiotic
prescribing may have become more common but also highlight relevant gaps in both
physicians' and public knowledge of antibiotics and AMR. To reinforce awareness
and close remaining gaps, Hungary should adopt its national AMR National Action
Plan and further increase its efforts towards active professional communication
and feedback for primary care physicians.
Claves:GENERAL MEDICINE (see Internal Medicine), Health policy, Public health
Cita:BMJ Open 2024 May 10; 14 (5) : e081574.
Autor/es:Babarczy, Balázs (a) Hajdu, Ágnes (b)
institución:(a) Syreon Research Institute, Budapest, Hungary. (b) National Center for Public Health and Pharmacy, Budapest, Hungary.
Conflicto:Competing interests: The National Center for Public Health and Pharmacy received funding and language editing support from the WHO Regional Office for Europe, for conducting this piece of research and preparing this manuscript.
Pharmaceutical treatment status of patients with COPD in the community based on medical Internet of Things: a real-world study.
Pharmaceutical treatment status of patients with COPD in the community based on medical Internet of Things: a real-world study.
Fuente:Npj Primary Care Respiratory Medicine
Extracto:
Enhancing general
practitioner proficiency in the prevention and management of COPD and increasing
patient awareness of the condition, are crucial standardising and improving
adherence to initial and follow-up COPD treatments.
Cita:NPJ Prim Care Respir Med 2024 May 10; 34 (1) : 10.
Autor/es:Wu, Peng (a) Jiang, Yi-Qun (b)
institución:(a) Department of Respiratory and Critical Care, Songjiang Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, 201600, China;Songjiang District Central Hospital, Shanghai, 201600, China. (b) Department of General Medicine, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Conflicto:All authors declare no competing interests.
Urosepsis 30-day mortality, morbidity, and their risk factors: SERPENS study, a prospective, observational multi-center study.
Urosepsis 30-day mortality, morbidity, and their risk factors: SERPENS study, a prospective, observational multi-center study.
Fuente:World Journal of Urology
Tipo de trabajo:Estudio multicéntrico
Extracto:
Impact of
comorbidities and MDR pathogens on outcomes highlights the existence of a
distinct group of patients who are prone to mortality and morbidity. These
findings underscore the need for the development of pragmatic classifications to
better assess the severity of UTIs and guide management strategies. STUDY
REGISTRATION: Clinicaltrials.gov registration number NCT02380170.
Claves:Antibiotic resistance, Severe UTI, Urosepsis
Cita:World J Urol 2024 May 10; 42 (1) : 314.
Autor/es:Tandogdu, Zafer (a) Koves, Bela (b)
institución:(a) University College London Hospitals, London, UK. drzafer@gmail.com. (b) Division of Surgery and Interventional Science, University College London, Charles Bell Housr, London, UK. drzafer@gmail.com.
Conflicto:Authors declare that they have no conflict of interest in keeping with the current research and manuscript.
Country-report pattern corrections of new cases allow accurate 2-week predictions of COVID-19 evolution with the Gompertz model.
Country-report pattern corrections of new cases allow accurate 2-week predictions of COVID-19 evolution with the Gompertz model.
Fuente:Scientific Reports
Extracto:
This increased to 3% for two-week predictions, and
only for three-week predictions it reached 10%.
Cita:Sci Rep 2024 May 11; 14 (1) : 10775.
Autor/es:Villanueva, I (a) Conesa, D (b)
institución:(a) Department of Physics, Universitat Politècnica de Catalunya (BarcelonaTech), 08860, Castelldefels, Spain. (b) Department of Information and Communication Technologies, Universitat Pompeu Fabra, 08018, Barcelona, Spain.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Severe fever with thrombocytopenia syndrome with central nervous system symptom onset
Severe fever with thrombocytopenia syndrome with central nervous system symptom onset
Fuente:Bmc Neurology
Tipo de trabajo:Revisión
Extracto:
This case gives us great insight that when patients with CNS symptoms
similar to those of viral encephalitis combined with thrombocytopenia and
leukopenia are encountered in the clinic, it is necessary to consider the
possibility of SFTS involving the CNS. Testing for SFTSV nucleic acid in CSF and
blood (mNGS or polymerase chain reaction (PCR)) should be carried out, especially
in critically ill patients, and treatment should be given accordingly.
Claves:Central nervous system, Encephalitis, Involuntary shaking, Novel bunyaviruses, Severe fever with thrombocytopenia syndrome
Cita:BMC Neurol 2024 May 10; 24 (1) : 158.
Autor/es:Shan, Dawei (a) Chen, Weibi (b)
institución:(a) Department of Neurology, Xuanwu Hospital, Capital Medical University, Beijing, 100053, China. (b) Department of Neurology, Xuanwu Hospital, Capital Medical University, Beijing, 100053, China.
Conflicto:All authors certify that they have no affiliations with or involvement in any organization or entity with any financial interest or nonfinancial interest in the subject matter or materials discussed in this manuscript.
institución:(a) Mycobacterial and Migrant Health Research Group, Department of Clinical Research, University of Basel Children's Hospital Basel, University of Basel, Spitalstrasse 33, Basel, CH-4031, Switzerland. (b) Mycobacterial and Migrant Health Research Group, Department of Clinical Research, University of Basel Children's Hospital Basel, University of Basel, Spitalstrasse 33, Basel, CH-4031, Switzerland.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
PaCO(2) is nonlinearly associated with NIV failure in patients with hypoxemic respiratory failure.
PaCO(2) is nonlinearly associated with NIV failure in patients with hypoxemic respiratory failure.
Fuente:Bmc Pulmonary Medicine
Extracto:
PaCO(2) and NIV failure was nonlinear relationship. The inflection
point was 32 mmHg. Below the inflection point, lower PaCO(2) was associated with
higher NIV failure. However, it did not associate with NIV failure above this
point.
institución:(a) Department of Respiratory and Critical Care Medicine, The First Affiliated Hospital of Chongqing Medical University, Youyi Road 1, Yuzhong District, Chongqing, 400016, P. R. China. (b) Department of Respiratory and Critical Care Medicine, The First Affiliated Hospital of Chongqing Medical University, Youyi Road 1, Yuzhong District, Chongqing, 400016, P. R. China.
Conflicto:We declare that we have no competing interests.
Mitochondrial DNA in bronchoalveolar lavage fluid is associated with the prognosis of idiopathic pulmonary fibrosis
Mitochondrial DNA in bronchoalveolar lavage fluid is associated with the prognosis of idiopathic pulmonary fibrosis
Fuente:Respiratory Research
Tipo de trabajo:Estudio de cohortes
Extracto:
Elevated BALF-mtDNA
was associated with a poor prognosis in both IPF and AE-IPF. Of note, at the time
of AE, it sharply distinguished survivors from non-survivors. Given the trends
shown by analyses for BALF-nucDNA, the elevation of BALF-mtDNA might not simply
reflect the impact of cell collapse. Further studies are required to explore the
underlying mechanisms and clinical applications of BALF-mtDNA in IPF.
Claves:Acute exacerbation, Bronchoalveolar lavage, Droplet digital PCR, Idiopathic pulmonary fibrosis, Interstitial lung disease, Mitochondrial DNA, Nucleolar DNA
Cita:Respir Res 2024 May 10; 25 (1) : 202.
Autor/es:Fukihara, Jun (a) Sakamoto, Koji (b)
institución:(a) Department of Respiratory Medicine and Allergy, Tosei General Hospital, Seto, Aichi, Japan. (b) Department of Respiratory Medicine, Nagoya University Graduate School of Medicine, 65 Tsurumai-Cho, Showa-Ku, Nagoya, Aichi, Japan.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Autor/es:Gajate-Arenas, Malena (a) Fricke-Galindo, Ingrid (b)
institución:(a) Instituto Universitario de Enfermedades Tropicales y Salud Pública de Canarias (IUETSPC), Universidad de La Laguna, 38029 San Cristóbal de La Laguna, Spain. (b) HLA Laboratory, Instituto Nacional de Enfermedades Respiratorias Ismael Cosío Villegas, Mexico City 14080, Mexico.
Conflicto:The authors declare that this research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflicts of interest.
Peptides Targeting the IF1-ATP Synthase Complex Modulate the Permeability Transition Pore in Cancer HeLa Cells.
Peptides Targeting the IF1-ATP Synthase Complex Modulate the Permeability Transition Pore in Cancer HeLa Cells.
Fuente:International Journal of Molecular Sciences
Extracto:
A third peptide was
identified which counteracts the anti-apoptotic role of IF1, showing that OSCP is
a promising target for anti-cancer therapies.
institución:(a) Department of Biomedical and Neuromotor Sciences, University of Bologna, 40126 Bologna, Italy. (b) Department of Chemical Science, University of Padova, 35121 Padova, Italy.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Plasma Metabolite Profiling in the Search for Early-Stage Biomarkers for Lung Cancer: Some Important Breakthroughs.
Plasma Metabolite Profiling in the Search for Early-Stage Biomarkers for Lung Cancer: Some Important Breakthroughs.
Fuente:International Journal of Molecular Sciences
Extracto:
This review highlights some key breakthroughs
in this research field, where the most significant biomarkers will be discussed
in relation to their metabolic pathways and in light of the altered cancer
metabolism.
Claves:NMR (nuclear magnetic resonance), biomarkers, lung cancer, metabolomics
Cita:Int J Mol Sci 2024 Apr 25; 25 (9)
Autor/es:Meynen, Jill (a) Adriaensens, Peter (b)
institución:(a) Faculty of Medicine and Life Sciences, Hasselt University, Martelarenlaan 42, B-3500 Hasselt, Belgium. (b) Applied and Analytical Chemistry, NMR Group, Institute for Materials Research (Imo-Imomec), Hasselt University, Agoralaan 1, B-3590 Diepenbeek, Belgium.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
institución:(a) Department of Clinical Immunology, Wroclaw Medical University, 51-616 Wroclaw, Poland. (b) Laboratory of Clinical Immunogenetics and Pharmacogenetics, Hirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, 53-114 Wroclaw, Poland.
Conflicto:E.W., M.C.-M. and D.G. have nothing to disclose. M.J. reports personal fees from ALK-Abello, Allergopharma, Stallergenes, Anergis, Allergy Therapeutics, Leti, and HAL, during the conduct of the study; personal fees from GSK, Novartis, Teva, Takeda, and Chiesi outside of the submitted work; and M.J. is the Allergy Journal Deputy Editor. M.Z.-W. is the European Academy of Allergy and Clinical Immunology...
Knowledge Hub Deputy Editor.
Interleukin-13 Treatment of Living Lung Tissue Model Alters the Metabolome and Proteome-A Nano-DESI MS Metabolomics and Shotgun Proteomics Study.
Interleukin-13 Treatment of Living Lung Tissue Model Alters the Metabolome and Proteome-A Nano-DESI MS Metabolomics and Shotgun Proteomics Study.
Fuente:International Journal of Molecular Sciences
Extracto:
This proof of principle study demonstrates
the utility of in vivo nano-DESI MS for characterizing ALI tissue layers, and the
new markers identified in our study provide a good starting point for future,
larger-scale studies.
institución:(a) Department of Chemistry-BMC, Uppsala University, 75237 Uppsala, Sweden. (b) Department of Chemistry-BMC, Uppsala University, 75237 Uppsala, Sweden.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Differences in the Course, Diagnosis, and Treatment of Food Allergies Depending on Age-Comparison of Children and Adults.
Differences in the Course, Diagnosis, and Treatment of Food Allergies Depending on Age-Comparison of Children and Adults.
Fuente:Nutrients
Extracto:
This article aims to systematize the
latest knowledge and highlight the differences between food allergies in
pediatric and adult populations.
Claves:IgE, anaphylaxis, basophil activation test, food allergy, lipid transfer protein, non-IgE mediated food allergy, omalizumab, oral food challenge test, oral immunotherapy, quality of life, skin prick test
Cita:Nutrients 2024 Apr 27; 16 (9)
Autor/es:Kuźniar, Julia (a) Kozubek, Patrycja (b)
institución:(a) Student Scientific Group of Internal Medicine and Allergology, Wroclaw Medical University, 50-369 Wroclaw, Poland. (b) Student Scientific Group of Internal Medicine and Allergology, Wroclaw Medical University, 50-369 Wroclaw, Poland.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Trophic Nutrition in ICU Patients Undergoing High-Flow Oxygen Therapy and/or Noninvasive Mechanical Ventilation: The Nutri-Trophic Study.
Trophic Nutrition in ICU Patients Undergoing High-Flow Oxygen Therapy and/or Noninvasive Mechanical Ventilation: The Nutri-Trophic Study.
Fuente:Nutrients
Extracto:
Early trophic feeding administered to patients with acute
respiratory failure requiring noninvasive ventilation is safe and feasible, and
is associated with few dietary and infectious complications in a mortality,
setting comparable to similar studies.
Autor/es:Reta-Pérez, Olivia (a) Colmenero-Ruiz, Manuel (b)
institución:(a) Department of Intensive Care, Hospital Universitario de Gran Canaria Dr. Negrín, Universidad de Las Palmas de Gran Canaria (ULPGC), Barranco de la Ballena s/n, 35010 Las Palmas de Gran Canaria, Spain. (b) Department of Intensive Care, Hospital Universitario San Cecilio, A. del Conocimiento s/n, 18016 Granada, Spain.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
The Knowledge of Malnutrition-Geriatric (KoM-G) 2.0 Questionnaire for Health Care Institutions: Cross-Cultural Adaptation into German, Czech, Dutch and Turkish.
The Knowledge of Malnutrition-Geriatric (KoM-G) 2.0 Questionnaire for Health Care Institutions: Cross-Cultural Adaptation into German, Czech, Dutch and Turkish.
Fuente:Nutrients
Extracto:
Afterwards it can be used to compare nurses' knowledge between
various countries and settings.
institución:(a) Department of Nursing Science, Medical University of Graz, Neue Stiftingtalstraße 6, 8010 Graz, Austria. (b) Faculty of Health Studies, University of Pardubice, Studentska 95, 532 10 Pardubice, Czech Republic.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Evaluating Seasonal Variations in Human Contact Patterns and Their Impact on the Transmission of Respiratory Infectious Diseases.
Evaluating Seasonal Variations in Human Contact Patterns and Their Impact on the Transmission of Respiratory Infectious Diseases.
Fuente:Influenza and Other Respiratory Viruses
Extracto:
Our findings support a relationship between temperature and contact
patterns, which can contribute to deepen the understanding of the relationship
between social interactions and the epidemiology of respiratory infectious
diseases.
Cita:Influenza Other Respir Viruses 2024 May; 18 (5) : e13301.
Autor/es:Kummer, Allisandra G (a) Zhang, Juanjuan (b)
institución:(a) Laboratory for Computational Epidemiology and Public Health, Department of Epidemiology and Biostatistics, Indiana University School of Public Health, Bloomington, Indiana, USA. (b) Shanghai Institute of Infectious Disease and Biosecurity, Department of Epidemiology, School of Public Health, Fudan University, Shanghai, China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Impact of Breathing Control Training Program on sonographic quantification of abdominal vasculature.
Impact of Breathing Control Training Program on sonographic quantification of abdominal vasculature.
Fuente:Saudi Medical Journal
Extracto:
The breathing training program saves
time and improves ultrasound measurement quality. Hospitals and health centers
should consider the importance of breathing control training programs before
abdominal scanning.
Autor/es:Hassan, Mahasin G (a) Alotaibi, Afnan M (b)
institución:(a) From the Department of Radiological Sciences (Hassan, Alotaibi, Altuwaym, Alnuwaysir, Alharbi, Alnajashi, Alsaber, Aldakan, Hawesa, Aldahes), College of Health and Rehabilitation Sciences, Princess Nourah bint Abdulrahman University; from Software Development Department (Yaqob), N24 Company Limited, Riyadh; and from the Department of Radiological Sciences (Abdelgabar), Al-Ghad International Colleges for Applied Sciences, Madina, Kingdom of Saudi Arabia. (b) From the Department of Radiological Sciences (Hassan, Alotaibi, Altuwaym, Alnuwaysir, Alharbi, Alnajashi, Alsaber, Aldakan, Hawesa, Aldahes), College of Health and Rehabilitation Sciences, Princess Nourah bint Abdulrahman University; from Software Development Department (Yaqob), N24 Company Limited, Riyadh; and from the Department of Radiological Sciences (Abdelgabar), Al-Ghad International Colleges for Applied Sciences, Madina, Kingdom of Saudi Arabia.
A mixed-methods study to investigate feasibility and acceptability of an early warning score for preterm infants in neonatal units in Kenya: results of the NEWS-K study Neonatal early warning scores in Kenya.
A mixed-methods study to investigate feasibility and acceptability of an early warning score for preterm infants in neonatal units in Kenya: results of the NEWS-K study Neonatal early warning scores in Kenya.
Fuente:Bmc Pediatrics
Extracto:
Newborn unit infant to
staff ratios varied between 10 and 53 staff per 1 infant, depending upon time of
shift and staff type. A randomised trial of neonatal EWS in Kenya is possible and
acceptable, though adaptations are required to the form before implementation.
Claves:Early warning score, Neonatal, Newborn unit
institución:(a) Nottingham Clinical Trials Unit, School of Medicine, University of Nottingham, Nottingham, UK. Eleanor.mitchell@nottingham.ac.uk. (b) Department of Paediatrics, University of Nairobi, Nairobi, Kenya.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
A modular motion compensation pipeline for prospective respiratory motion correction of multi-nuclear MR spectroscopy.
A modular motion compensation pipeline for prospective respiratory motion correction of multi-nuclear MR spectroscopy.
Fuente:Scientific Reports
Extracto:
This and the modular structure of the pipeline allows for the
proposed method to be used in imaging of moving organs and in challenging
applications like cardiac magnetic resonance spectroscopy (MRS) or magnetic
resonance imaging (MRI) guided radiotherapy.
institución:(a) High Field MR Center, Center for Medical Physics and Biomedical Engineering, Medical University of Vienna, Vienna, Austria. (b) High Field MR Center, Center for Medical Physics and Biomedical Engineering, Medical University of Vienna, Vienna, Austria.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación