Four key problems that will need to be addressed during the next pandemic.

Fuente:Clinical Medicine (london, England)

Extracto: Finally, there was worsening of existing inequalities, especially in ethnic minority groups, that resulted in excessive numbers within certain cohorts becoming infected.

Claves:COVID-19, SARS-CoV-2, aerosol-generating procedures, pandemic preparedness, paradigm shift

Cita:Clin Med (Lond) 2023 Sep; 23 (5) : 527-530.

Autor/es:Pan, Daniel (a)
Tang, Julian W (b)

institución:(a) Leicester Biomedical Research Centre, Leicester, UK; University Hospitals of Leicester NHS Trust, Leicester, UK; Li Ka Shing Institute of Health Information and Discovery, University of Oxford, Oxford, UK.
(b) University Hospitals of Leicester NHS Trust, Leicester, UK; University of Leicester, Leicester, UK. Electronic address: Julian.tang@uhl-tr.nhs.uk.

Formato:Informe impreso

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.7861/clinmed.2023-0283

Do respiratory physicians not care about people who smoke?

Fuente:Clinical Medicine (london, England)

Extracto: In this opinion article we discuss clinicians' views of vaping and consider the implications that harm misperceptions may have for public health.

Claves:e-cigarette, harm reduction, smoking cessation, vaping

Cita:Clin Med (Lond) 2023 Sep; 23 (5) : 531-532.

Autor/es:Notley, Caitlin (a)
Barry, Simon (b)

institución:(a) Faculty of Medicine and Health Sciences, Norwich Medical School, University of East Anglia, Norwich, UK. Electronic address: c.notley@uea.ac.uk.
(b) Cardiff and Vale University Health Board and Lead, National Respiratory Health Implementation Group, Wales.

Formato:Informe impreso

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.7861/clinmed.2023-0270

The responses of pepper plants to nitrogen form and dissolved oxygen concentration of nutrient solution in hydroponics.

Fuente:Bmc Plant Biology

Extracto: This study showed that, the growth and photosynthesis parameters in bell pepper plants are sensitive to oxygen stress in floating hydroponic culture. Therefore, the oxygen level in the nutrient solution must not be lower than 3.8 and 5.3 mg. L(-1) in NH(4)(+) and NO(3)(-) -supplied culture media or nutrient solutions, respectively.

Claves:Capsicum annuum, Ammonium, Nitrate, Oxygen, Soilless culture

Cita:BMC Plant Biol 2024 Apr 13; 24 (1) : 281.

Autor/es:Capsicum annuum, Ammonium, Nitrate, Oxygen, Soilless culture

institución:Capsicum annuum, Ammonium, Nitrate, Oxygen, Soilless culture

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1186/s12870-024-04943-7

STING agonist diABZI enhances the cytotoxicity of T cell towards cancer cells.

Fuente:Cell Death & Disease

Extracto: This indicates that STING agonist could be used as a strategy to promote TCR-T cancer immunotherapy.

Cita:Cell Death Dis 2024 Apr 13; 15 (4) : 265.

Autor/es:Wang, Ling (a)
Liang, Zhaoduan (b)

institución:(a) Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, 230026, China.
(b) CAS Key Laboratory of Regenerative Biology, Guangdong Provincial Key Laboratory of Stem Cell and Regenerative Medicine, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, 510530, China.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1038/s41419-024-06638-1

Smoking on the risk of acute respiratory distress syndrome

Fuente:Critical Care (london, England)

Tipo de trabajo:Revisión sistemática

Extracto: There is a strong association between smoking and elevated ARDS risk. This emphasizes the need for thorough assessment of patients' smoking status, urging healthcare providers to vigilantly monitor individuals with a history of smoking, especially those with additional extrapulmonary risk factors for ARDS.

Claves:Acute respiratory distress syndrome, Meta-analysis, Smoking, Systematic review

Cita:Crit Care 2024 Apr 14; 28 (1) : 122.

Autor/es:Zhang, Lujia (a)
Xu, Jiahuan (b)

institución:(a) Institute of Respiratory and Critical Care Medicine, The First Hospital of China Medical University, No. 155 Nanjing North Street, Heping District, Shenyang, 110001, Liaoning, China.
(b) Institute of Respiratory and Critical Care Medicine, The First Hospital of China Medical University, No. 155 Nanjing North Street, Heping District, Shenyang, 110001, Liaoning, China.

Conflicto:We declare no competing interests.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1186/s13054-024-04902-6

Novel application of nanomedicine for the treatment of acute lung injury

Fuente:Therapeutic Advances in Respiratory Disease

Tipo de trabajo:Revisión

Extracto: Ultimately, these nanomedicines will be used for the clinical treatment of ALI/ARDS.

Claves:acute lung injury, nanocarriers, nanovaccines, nanozymes, therapy

Cita:Ther Adv Respir Dis 2024 Jan-Dec; 18 : 17534666241244974.

Autor/es:Chen, Xianfeng (a)
Tang, Zhanhong (b)

institución:(a) Department of Intensive Care Unit, The First Affiliated Hospital of Guangxi Medical University, Nanning, PR China.
(b) Department of Intensive Care Unit, the First Affiliated Hospital of Guangxi Medical University, No. 6 Shuangyong Road, Nanning 530021, China.

Conflicto:The authors declare that there is no conflict of interest.

Formato:Informe impreso

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1177/17534666241244974

Group A Streptococcus Carriage in Adults in Southern Israel: A Prospective Study.

Fuente:The Israel Medical Association Journal Imaj

Extracto: Being an ultra-Orthodox Jew was the single variable associated with a GAS carriage, which may be related to having many children at home and living in overcrowded areas. Primary care physicians in Israel should recognize this situation when examining patients with sore throats, mainly ultra-Orthodox Jews.

Cita:Isr Med Assoc J 2024 Apr; 26 (4) : 232-235.

Autor/es:Adler, Limor (a)
Tzadok Zehavi, Or (b)

institución:(a) Department of Family Medicine, Maccabi Healthcare Services, Tel Aviv, Israel, Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
(b) Department of Family Medicine, Maccabi Healthcare Services, Tel Aviv, Israel, Department of Family Medicine, Faculty of Health Sciences, Ben Gurion University of the Negev, Beer Sheva, Israel.

Formato:Informe impreso

Idioma:Inglés

País de fuente:Israel

Sitio web:

A putative role for lactate in the crosstalk between chemokines and glycolysis in solid cancer.

Fuente:International Journal of Biological Sciences

Extracto: In this paper we explore the interplay between chemokines, glycolysis, and lactate in cancer progression, and propose the existence of a pro-tumoral lactate-chemokine-glycolysis loop driven by high glucose levels.

Claves:cancer, chemokines, glycolysis, lactate

Cita:Int J Biol Sci 2024; 20 (6) : 2261-2263.

Autor/es:Rivas-Fuentes, Selma (a)
Santos-Mendoza, Teresa (b)

institución:(a) Laboratory of Transcriptomics and Molecular Immunology, Instituto Nacional de Enfermedades Respiratorias "Ismael Cosío Villegas", Mexico City, Mexico.
(b) Laboratory of Transcriptomics and Molecular Immunology, Instituto Nacional de Enfermedades Respiratorias "Ismael Cosío Villegas", Mexico City, Mexico.

Conflicto:Competing Interests: The authors have declared that no competing interest exists.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Australia

Sitio web:http://dx.doi.org/10.7150/ijbs.91108

Auriculocondylar syndrome 2 caused by a novel PLCB4 variant in a male Chinese neonate

Fuente:Molecular Genetics & Genomic Medicine

Tipo de trabajo:Revisión

Extracto: As with other studies examining familial cases of ARCND2, incomplete penetrance and variable expressivity were observed within different families' heterozygous mutations in PLCB4 gene. Although, motor and intellectual development are in the normal range in the vast majority of patients with ARCND2, long-term follow-up and assessment are still required.

Claves:PLCB4, Auriculocondylar syndrome, craniofacial deformity, neonate, question mark ear

Cita:Mol Genet Genomic Med 2024 Apr; 12 (4) : e2441.

Autor/es:Zhang, Yongli (a)
Zhao, Yuwei (b)

institución:(a) Department of Neonatology, Anhui Provincial Children's Hospital/Children's Hospital of Fudan University (Affiliated Anhui Branch), Hefei, Anhui, China.
(b) Department of Neonatology, Anhui Provincial Children's Hospital/Children's Hospital of Fudan University (Affiliated Anhui Branch), Hefei, Anhui, China.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe impreso

Idioma:Inglés

País de fuente:EE.UU.

Sitio web:http://dx.doi.org/10.1002/mgg3.2441

Seasonal extreme temperatures and short-term fine particulate matter increases pediatric respiratory healthcare encounters in a sparsely populated region of the intermountain western United States.

Fuente:Environmental Health a Global Access Science Source

Extracto: Delayed, short-term exposure increases of PM(2.5) were associated with elevated odds of all three pediatric respiratory healthcare visit categories in a sparsely population area of the inter-Rocky Mountains, USA. PM(2.5) in colder temperatures tended to increase instances of asthma and LRTIs, while PM(2.5) during hotter periods increased URTIs.

Claves:Asthma, Case-crossover design, Distributed lag modeling, Environmental health, Environmental public health, Fine particulate matter air pollution, Hospital discharge data, Lag effects, Lower respiratory tract infections, Montana, PM2.5, Respiratory infections, Rural, Upper respiratory tract infections, Wildfire smoke, Woodfire smoke

Cita:Environ Health 2024 Apr 15; 23 (1) : 40.

Autor/es:Landguth, Erin L (a)
Knudson, Jonathon (b)

institución:(a) Center for Population Health Research, School of Public and Community Health Sciences, University of Montana, 32 Campus Drive, Missoula, MT, 59812, USA. erin.landguth@mso.umt.edu.
(b) Center for Population Health Research, School of Public and Community Health Sciences, University of Montana, 32 Campus Drive, Missoula, MT, 59812, USA.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1186/s12940-024-01082-2

Air Pollution Drives Macrophage Senescence through a Phagolysosome-15-Lipoxygenase Pathway.

Fuente:Immunohorizons

Extracto: These data suggest that uPM exposure leads to macrophage senescence, which may contribute to immunopathology.

Cita:Immunohorizons 2024 Apr 1; 8 (4) : 307-316.

Autor/es:Thomas, Sarah A (a)
Yong, Hwan Mee (b)

institución:(a) W. Harry Feinstone Department of Molecular Microbiology and Immunology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD.
(b) Department of Environmental Health and Engineering, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD.

Formato:Informe impreso

Idioma:Inglés

País de fuente:EE.UU.

Sitio web:http://dx.doi.org/10.4049/immunohorizons.2300096

Assessing the Clinical Impact of the SARS-CoV-2 Gamma Variant on Intensive Care Unit Admissions: Insights from a Reference Hospital in Northeastern Brazil.

Assessing the Clinical Impact of the SARS-CoV-2 Gamma Variant on Intensive Care Unit Admissions: Insights from a Reference Hospital in Northeastern Brazil.

Fuente:Viruses

Extracto: Overall, this research contributes valuable insights into the impact of the Gamma variant on COVID-19 dynamics, advocating for continued research and surveillance to inform effective public health strategies regarding evolving viral variants.

Claves:SARS-CoV-2, coronavirus disease-19 (COVID-19), gamma

Cita:Viruses 2024 Mar 20; 16 (3)

Autor/es:Nonaka, Carolina Kymie Vasques (a)
de Jesus Ribeiro, Adlas Michel (b)

institución:(a) D'Or Institute for Research and Education (IDOR), Salvador 41253-190, BA, Brazil.
(b) São Rafael Hospital, Salvador 41253-190, BA, Brazil.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3390/v16030467

An Evaluation of Type 1 Interferon Related Genes in Male and Female-Matched, SARS-CoV-2 Infected Individuals Early in the COVID-19 Pandemic.

Fuente:Viruses

Extracto: We concluded that TLR-7 and TLR-4 agonists may be effective adjuvants in COVID-19 vaccines for mounting immunity that is long-lasting against SARS-CoV-2 infection.

Claves:COVID-19, IFNα, IFNγ, IL-6, Lipopolysaccharide (LPS), SARS-CoV-2, group 2 ILC (ILC2), group 3 ILC (ILC3), innate lymphoid cells (ILC), interferon stimulated genes (ISG), natural killer cells (NK), pathogen associated molecular patterns (PAMP), pattern recognition receptors (PRR), toll-like receptor (TLR)

Cita:Viruses 2024 Mar 20; 16 (3)

Autor/es:Huecksteadt, Tom P (a)
Myers, Elizabeth J (b)

institución:(a) Salt Lake City VA Medical Center, Salt Lake City, UT 84148, USA.
(b) Salt Lake City VA Medical Center, Salt Lake City, UT 84148, USA.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3390/v16030472

Comparative study between poorly differentiated thyroid cancer and anaplastic thyroid cancer: real-world pathological distribution, death attribution, and prognostic factor estimation.

Comparative study between poorly differentiated thyroid cancer and anaplastic thyroid cancer: real-world pathological distribution, death attribution, and prognostic factor estimation.

Fuente:Frontiers in Endocrinology

Tipo de trabajo:Orientaciones y guía

Extracto: The populational analysis of the PDTC/ATC cohort has provided reliable support for better understanding of the difference between PDTC and ATC cases and the guidance of clinical practice and further studies.

Claves:anaplastic thyroid carcinoma, death attribution, pathological distribution, poorly differentiated thyroid carcinoma, prognostic factor

Cita:Front Endocrinol (Lausanne) 2024; 15 : 1347362.

Autor/es:Zhang, Kun (a)
Wang, Xinyi (b)

institución:(a) Division of Thyroid Surgery, Department of General Surgery, West China Hospital, Sichuan University, Chengdu, Sichuan, China.
(b) Division of Thyroid Surgery, Department of General Surgery, West China Hospital, Sichuan University, Chengdu, Sichuan, China.

Conflicto:The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3389/fendo.2024.1347362

Case report

Fuente:Frontiers in Endocrinology

Tipo de trabajo:Revisión

Extracto: This is the first case of MAD syndrome caused by mutations in MTX2 gene reported in the Chinese population. MTX2 gene c.378 + 1G > A homozygous mutation has not been previously reported and the report of this patient expands the spectrum of MTX2 mutations. In addition, we summarized the genotypes and clinical characteristics of patients with progeroid syndromes in China.

Claves:MTX2 gene, exon skipping, mandibular hypoplasia (MAD) syndrome, progeria syndrome, splice-site mutation

Cita:Front Endocrinol (Lausanne) 2024; 15 : 1345067.

Autor/es:Fu, Xiaohui (a)
Chen, Shuli (b)

institución:(a) Department of Inherited Metabolic Disorders, Shenzhen Children's Hospital, Shenzhen, China.
(b) Department of Inherited Metabolic Disorders, Shenzhen Children's Hospital, Shenzhen, China.

Conflicto:The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3389/fendo.2024.1345067

Age differences in the association of body mass index-defined obesity with abdominal aortic calcification.

Fuente:Frontiers in Endocrinology

Extracto: In US, adults aged 52 years or older, obesity was associated with decreased AAC risk. Older age may be one potential reason for the obesity paradox.

Claves:NHANES, abdominal vascular calcification, age, body mass index, obesity

Cita:Front Endocrinol (Lausanne) 2024; 15 : 1336053.

Autor/es:Guo, Tangmeng (a)
Huang, Lili (b)

institución:(a) Department of Geriatrics, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
(b) Institute of Gerontology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.

Conflicto:The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3389/fendo.2024.1336053

The effects of vitamin D supplementation on inflammatory biomarkers in patients with asthma

The effects of vitamin D supplementation on inflammatory biomarkers in patients with asthma

Fuente:Frontiers in Immunology

Tipo de trabajo:Revisión sistemática

Extracto: Vitamin D supplementation in individuals with asthma was not associated with lower inflammatory biomarkers related to type 2 inflammation. However, it was significantly associated with higher serum IL-10 compared to placebo. SYSTEMATIC REVIEW REGISTRATION: https://www.crd.york.ac.uk/PROSPERO/, identifier CRD42022365666.

Claves:asthma, biomarkers, inflammation, meta-analysis, systematic review, vitamin D

Cita:Front Immunol 2024; 15 : 1335968.

Autor/es:El Abd, Asmae (a)
Dasari, Harika (b)

institución:(a) Sainte-Justine University Health Center, Research Center, Montreal, QC, Canada.
(b) Department of Social and Preventive Medicine, School of Public Health, University of Montreal, Montreal, QC, Canada.

Conflicto:FMD has received unrestricted research funds from Jamieson and GSK, as well as investigator initiated research funds from Covis Pharma, Banque Scotia Foundation, GlaxoSmithKline, and MEDteq in partnership with Thorasys Inc. FMD has received an honorarium for consultancy work from INESSS, Astra Zeneca, Covis Pharma, Ontario Lung Association, Sanofi, and Teva. FMD has also been on the advisory board for... Sanofi and has received honoraria as an invited speaker from the Association des Médecins omnipraticiens du Richelieu Saint-Laurent, Covis Pharma, Réseau québécois d’éducation en santé respiratoire (RQESR), Sanofi-Regeneron, Thorasys Inc., and Trudell Medical International. HT reported receiving occasional lecture fees from Merck and unrestricted grants form ViiV Healthcare. The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3389/fimmu.2024.1335968

Influence of epicardial adipose tissue inflammation and adipocyte size on postoperative atrial fibrillation in patients after cardiovascular surgery.

Influence of epicardial adipose tissue inflammation and adipocyte size on postoperative atrial fibrillation in patients after cardiovascular surgery.

Fuente:Physiological Reports

Extracto: In conclusion, changes in the secretory profile and adipocyte morphology of the EAT, which represent qualitative aspects of the adipose tissue, were present before the onset of AF.

Claves:adipocyte size, epicardial adipose tissue, inflammatory mediators, mitochondrial respiratory capacity, postoperative atrial fibrillation

Cita:Physiol Rep 2024 Mar; 12 (6) : e15957.

Autor/es:Natsui, Hiroyuki (a)
Watanabe, Masaya (b)

institución:(a) Department of Cardiovascular Medicine, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Sapporo, Japan.
(b) Department of Cardiovascular Medicine, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Sapporo, Japan.

Conflicto:No conflicts of interest, financial or otherwise, are declared by the authors.

Formato:Informe impreso

Idioma:Inglés

País de fuente:EE.UU.

Sitio web:http://dx.doi.org/10.14814/phy2.15957

Should atelectasis be considered a pulmonary complication and indicator of poor prognosis in cystic fibrosis?

Should atelectasis be considered a pulmonary complication and indicator of poor prognosis in cystic fibrosis?

Fuente:The Journal of International Medical Research

Extracto: Moderate-to-severe pulmonary disease and ABPA can favor atelectasis. Pulmonary atelectasis can be a poor prognostic factor in CF because it increases exacerbations. Despite our results, we recommend enhancing treatment, including bronchoscopy, to prevent persistent atelectasis.

Claves:Cystic fibrosis, allergic bronchopulmonary aspergillosis, atelectasis, bronchoscopy, exacerbation, prognosis, risk factor

Cita:J Int Med Res 2024 Mar; 52 (3) : 3000605241233520.

Autor/es:Martínez Redondo, María (a)
Carpio Segura, Carlos (b)

institución:(a) Respiratory Department, CIBERES, Hospital La Paz Institute for Health Research-IdiPAZ, La Paz University Hospital-Autónoma University of Madrid, Madrid, Spain.
(b) Respiratory Department, CIBERES, Hospital La Paz Institute for Health Research-IdiPAZ, La Paz University Hospital-Autónoma University of Madrid, Madrid, Spain.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe impreso

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1177/03000605241233520

Myelin oligodendrocyte glycoprotein antibody-associated disease with clinical presentation as multiple episodes of isolated meningeal involvement

Fuente:The Journal of International Medical Research

Tipo de trabajo:Caso clínico

Extracto: Consequently, MOGAD should be considered in cases of aseptic meningitis with an unknown etiology, to facilitate definitive diagnosis and enhance patient prognosis.

Claves:Myelin oligodendrocyte glycoprotein antibody-associated disease, aseptic meningitis, autoimmune inflammatory demyelinating disease, central nervous system, differential diagnosis, relapsing meningitis

Cita:J Int Med Res 2024 Mar; 52 (3) : 3000605241233157.

Autor/es:Wei, Xiaojie (a)
Zhao, Chentong (b)

institución:(a) Department of Oncology, Hengshui People's Hospital, Hengshui, China.
(b) Department of Respiratory, Hengshui People's Hospital, Hengshui, China.

Conflicto:Declaration of conflicting interestThe authors declare that there is no conflict of interest.

Formato:Informe impreso

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1177/03000605241233157