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Associations of U.S. state-level COVID-19 policies intensity with cannabis sharing behaviors in 2020.
Associations of U.S. state-level COVID-19 policies intensity with cannabis sharing behaviors in 2020.
Fuente:Harm Reduction Journal
Extracto:
Fewer individuals shared cannabis in
states with more intense COVID-19 containment policies compared to those in
states with less intense policies. Individuals who use cannabis may be willing to
make changes to their behavior and may further benefit from specific and directed
public health messaging to avoid sharing during respiratory infection outbreaks.
Claves:COVID-19, Cannabis, Harm reduction, Pandemic, Policy evaluation, Public Health, Respiratory
Cita:Harm Reduct J 2024 Apr 16; 21 (1) : 82.
Autor/es:Assaf, Ryan D (a) Hamad, Rita (b)
institución:(a) UCLA Center for Cannabis and Cannabinoids, Jane and Terry Semel Institute for Neuroscience and Human Behavior, University of California, Los Angeles, CA, USA. ryan.assaf@ucsf.edu. (b) Department of Epidemiology, Fielding School of Public Health, University of California, Los Angeles, CA, USA. ryan.assaf@ucsf.edu.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Antimicrobial resistance prediction by clinical metagenomics in pediatric severe pneumonia patients.
Antimicrobial resistance prediction by clinical metagenomics in pediatric severe pneumonia patients.
Fuente:Annals of Clinical Microbiology and Antimicrobials
Extracto:
mNGS exhibits variable
predictive performance among different pathogens and antibiotics, indicating its
potential as a supplementary tool to conventional PST. However, mNGS currently
cannot replace conventional PST.
Claves:Antimicrobial resistance, Metagenomic next-generation sequencing, Pediatric, Severe pneumonia
institución:(a) Center for Molecular Medicine, Children's Hospital of Fudan University, National Children's Medical Center, Shanghai, 201102, People's Republic of China. (b) Department of Neonatology, Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, 325000, China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
RSV Disease Burden in Primary Care in Italy: A Multi-Region Pediatric Study, Winter Season 2022-2023.
RSV Disease Burden in Primary Care in Italy: A Multi-Region Pediatric Study, Winter Season 2022-2023.
Fuente:Influenza and Other Respiratory Viruses
Extracto:
Our findings describe a baseline of
the RSV disease burden in primary care in Italy before the introduction of
upcoming immunization strategies.
Claves:RSV, acute respiratory infections, primary care, respiratory infection surveillance
Cita:Influenza Other Respir Viruses 2024 Apr; 18 (4) : e13282.
Autor/es:Scarpaci, Michela (a) Bracaloni, Sara (b)
institución:(a) Department of Translational Research and New Technologies in Medicine and Surgery, University of Pisa, Pisa, Italy. (b) Department of Translational Research and New Technologies in Medicine and Surgery, University of Pisa, Pisa, Italy.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Comparative Analysis of Clinical Outcomes Using Propensity Score Matching: Coronavirus Disease 2019 vs. Seasonal Influenza in Korea.
Comparative Analysis of Clinical Outcomes Using Propensity Score Matching: Coronavirus Disease 2019 vs. Seasonal Influenza in Korea.
Fuente:Journal of Korean Medical Science
Extracto:
The omicron group did not demonstrate better clinical outcomes
than the pre-omicron group, and exhibited significant disease severity compared
to the influenza group. Considering the likely persistence of COVID-19
infections, it is imperative to sustain comprehensive studies and ongoing policy
support for the virus to enhance the prognosis for individuals affected by
COVID-19.
Cita:J Korean Med Sci 2024 Apr 15; 39 (14) : e128.
Autor/es:Sim, Jae Kyeom (a) Lee, Hye Sun (b)
institución:(a) Division of Pulmonary, Allergy, and Critical Care Medicine, Department of Internal Medicine, Korea University Guro Hospital, Seoul, Korea. (b) Biostatistics Collaboration Unit, Yonsei University College of Medicine, Seoul, Korea.
Conflicto:The authors have no potential conflicts of interest to disclose.
Comparison of the Clinical Outcomes Between Early and Delayed Transplantation After SARS-CoV-2 Infection.
Comparison of the Clinical Outcomes Between Early and Delayed Transplantation After SARS-CoV-2 Infection.
Fuente:Journal of Korean Medical Science
Extracto:
Therefore,
transplantation needs not be delayed by COVID-19 infection.
Claves:COVID-19, Hematopoietic Stem Cell Transplantation, SARS-CoV-2 Infection, Solid Organ Transplantation
Cita:J Korean Med Sci 2024 Apr 15; 39 (14) : e137.
Autor/es:Ra, Sang Hyun (a) Kim, A Reum (b)
institución:(a) Department of Infectious Diseases, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea. (b) Department of Infectious Diseases, Pusan National University Yangsan Hospital, Pusan National University School of Medicine, Yangsan, Korea.
Conflicto:The authors have no potential conflicts of interest to disclose.
The Cellular Respiration of Endometrial Biopsies from Patients with Various Forms of Endometriosis.
The Cellular Respiration of Endometrial Biopsies from Patients with Various Forms of Endometriosis.
Fuente:International Journal of Molecular Sciences
Extracto:
These data allow us to suggest that
the therapeutic strategies of endometriosis based on modulation energy metabolism
should take lesion localization into account.
Autor/es:Toniyan, Konstantin A (a) Malkov, Artyom A (b)
institución:(a) Cell Biophysics Laboratory, State Scientific Center of the Russian Federation Institute of Biomedical Problems of the Russian Academy of Sciences, 123007 Moscow, Russia. (b) Gynecology Department, FGBU KB1 (Volynskaya) UDP RF, 121352 Moscow, Russia.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Mobocertinib in Patients with EGFR Exon 20 Insertion-Positive Non-Small Cell Lung Cancer (MOON): An International Real-World Safety and Efficacy Analysis.
Mobocertinib in Patients with EGFR Exon 20 Insertion-Positive Non-Small Cell Lung Cancer (MOON): An International Real-World Safety and Efficacy Analysis.
Fuente:International Journal of Molecular Sciences
Extracto:
Mobocertinib demonstrated meaningful efficacy in a real-world setting but was
associated with considerable gastrointestinal and cutaneous toxicity.
Autor/es:Illini, Oliver (a) Saalfeld, Felix Carl (b)
institución:(a) Department of Respiratory and Critical Care Medicine, Klinik Floridsdorf, Vienna Healthcare Group, Bruenner Straße 68, A-1210 Vienna, Austria. (b) Karl Landsteiner Institute of Lung Research and Pulmonary Oncology, A-1210 Vienna, Austria.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Current remarks and future directions on the interactions between metabolic dysfunction-associated fatty liver disease and COVID-19.
Current remarks and future directions on the interactions between metabolic dysfunction-associated fatty liver disease and COVID-19.
Fuente:World Journal of Gastroenterology
Extracto:
Reducing
morbidity and mortality of patients with COVID-19 and MAFLD should be the
ultimate objective, and the optimal way to achieve this is by designing
evidence-based prevention and treatment policies.
institución:(a) School of Medicine, National & Kapodistrian University of Athens, Athens 11527, Greece. (b) School of Medicine, National & Kapodistrian University of Athens, Athens 11527, Greece.
Conflicto:Conflict-of-interest statement: Leonidas Brilakis, Eirini Theofilogiannakou and Panagis M Lykoudis have nothing to disclose.
The effect of respiratory muscle training on children and adolescents with cystic fibrosis
The effect of respiratory muscle training on children and adolescents with cystic fibrosis
Fuente:Bmc Pediatrics
Tipo de trabajo:Revisión sistemática
Extracto:
This systematic review and meta-analysis indicate that although the level of
evidence indicating the benefits of respiratory muscle training is low, its
clinical significance suggests that we further study the methodological quality
to determine the effectiveness of training. TRIAL REGISTRATION: The protocol for
this review was recorded in the International Prospective Register of Systematic
Reviews (PROSPERO) under registration number CRD42023441829.
Claves:Adolescent, Cystic fibrosis, Pediatrics, Pulmonary rehabilitation, Respiratory muscle training
Cita:BMC Pediatr 2024 Apr 15; 24 (1) : 252.
Autor/es:Cai, WenQian (a) Li, Meng (b)
institución:(a) School of Pediatrics, Nanjing Medical University, Jiangsu Province, China. (b) Department of Nursing, Children's Hospital of Nanjing Medical University, Nanjing, China.
Dual rare genetic diseases in five pediatric patients: insights from next-generation diagnostic methods.
Dual rare genetic diseases in five pediatric patients: insights from next-generation diagnostic methods.
Fuente:Orphanet Journal of Rare Diseases
Extracto:
Our findings underscore the importance of
clinicians being vigilant about the significance of historical and physical
examination. Comprehensive clinical experience is crucial for identifying
atypical clinical features, particularly in cases involving dual rare genetic
diseases.
institución:(a) Department of Pediatrics, Peking University People's Hospital, Beijing, China. (b) Department of Pediatrics, Peking University First Hospital, Beijing, China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
A retrospective study of morbidity and mortality of chronic acid sphingomyelinase deficiency in Germany.
A retrospective study of morbidity and mortality of chronic acid sphingomyelinase deficiency in Germany.
Fuente:Orphanet Journal of Rare Diseases
Tipo de trabajo:Estudio de cohortes
Extracto:
This study highlights considerable morbidity and
mortality associated with ASMD type B and type A/B in Germany. It further
emphasises the importance of effective therapy for chronic ASMD to reduce disease
complications.
Claves:Acid sphingomyelinase deficiency, Morbidity, Mortality, Overall survival, Standardised mortality ratio
institución:(a) Institute of Clinical Science for LSD, SphinCS, Hochheim, Germany. (b) International Center for Lysosomal Disorders (ICLD), University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Conflicto:EM has received research grants, speakers’ honoraria, and consultation fees from Sanofi, Takeda, Orphazyme, Avrobio, Idorsia, Cyclo Therapeutics, Alexion, and Amicus. NM has received research grants, speakers’ honoraria, and/or consultation fees from Sanofi, Takeda, Amicus, Chiesi, JCR, and Lysogene. NW has received research grants, speakers’ honoraria, travel grants, and/or consultation fees from Sanofi, Takeda, and Biomarin. AZ has received speakers’...
akers’ honoraria and consultation fees from Sanofi, Genzyme, Takeda, and Biomarin. JN has received travel grants from Sanofi, Takeda, and Biomarin. BA and LL are employees of IQVIA. MG, SG, MF, and RPJ are employees and may hold stock and/or stock options in Sanofi. FL was an employee of Sanofi at the time of study conduct.
Substance P Concentration in Gestational Diabetes and Excessive Gestational Weight Gain and Its Impact on Neonatal Anthropometry.
Substance P Concentration in Gestational Diabetes and Excessive Gestational Weight Gain and Its Impact on Neonatal Anthropometry.
Fuente:International Journal of Molecular Sciences
Extracto:
To our knowledge, it is the
first study assessing substance P concentration in GDM and EGWG patients.
Claves:excessive gestational weight gain, fetal programming, gestational diabetes mellitus, substance P
Cita:Int J Mol Sci 2024 Mar 28; 25 (7)
Autor/es:Niebrzydowska-Tatus, Magdalena (a) Pełech, Aleksandra (b)
institución:(a) Chair and Department of Obstetrics and Perinatology, Medical University of Lublin, 20-090 Lublin, Poland. (b) Chair and Department of Obstetrics and Perinatology, Medical University of Lublin, 20-090 Lublin, Poland.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Lipopolysaccharide binding protein resists hepatic oxidative stress by regulating lipid droplet homeostasis.
Lipopolysaccharide binding protein resists hepatic oxidative stress by regulating lipid droplet homeostasis.
Fuente:Nature Communications
Extracto:
These insights could inform the development of redox-based therapies for
alleviating oxidative stress-induced metabolic dysfunction.
Cita:Nat Commun 2024 Apr 13; 15 (1) : 3213.
Autor/es:Zhang, Qilun (a) Shen, Xuting (b)
institución:(a) Laboratory of Diabetes, Department of Endocrinology, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui, 230001, China. (b) Department of Pathophysiology, Anhui Medical University, Hefei, Anhui, 230000, China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Oxidative Stress Induced by Cortisol in Human Platelets.
Oxidative Stress Induced by Cortisol in Human Platelets.
Fuente:International Journal of Molecular Sciences
Extracto:
It is likely that, in human
platelets, oxidative stress induced by cortisol can be associated with venous and
arterial thrombosis, greatly contributing to cardiovascular diseases.
Claves:aerobic metabolism, cortisol, human platelets, oxidative stress
Cita:Int J Mol Sci 2024 Mar 28; 25 (7)
Autor/es:Signorello, Maria Grazia (a) Ravera, Silvia (b)
institución:(a) Biochemistry Laboratory, Department of Pharmacy, University of Genoa, 16132 Genova, Italy. (b) Department of Experimental Medicine, University of Genoa, 16132 Genova, Italy.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Trajectory of cardiac troponin T following moderate-to-severe COVID-19 and the association with cardiac abnormalities.
Trajectory of cardiac troponin T following moderate-to-severe COVID-19 and the association with cardiac abnormalities.
Fuente:Bmc Cardiovascular Disorders
Extracto:
Higher hs-cTnT concentrations in the
convalescent phase of COVID-19 are associated with the presence of cardiac
pathology and low concentrations (< 5 ng/L) may support in ruling out cardiac
pathology following the infection.
institución:(a) Department of Cardiology, Division of Medicine, Akershus University Hospital, Lørenskog, Norway. (b) K.G. Jebsen Center for Cardiac Biomarkers, Institute for Clinical Medicine, University of Oslo, Oslo, Norway.
Conflicto:P.L.M has served on advisory boards and/or received speaker fees from Amarin, AmGen, AstraZeneca, Bayer, Boehringer Ingelheim, Novartis, Novo Nordisk, Pharmacosmos, Vifor and Us2.ai, unrelated to this work. C.I and J.G have received fees for lectures from Bayer AG. J.G has received fees for participating in an expert panel from Sanofi, unrelated to this work. S.A. has received speaker honoraria...
from Bayer and Novartis. T.O. has received consultancy and speaker honoraria from Abbott Diagnostics, Roche Diagnostics, and Novartis, and research support via Akershus University Hospital from Thermo Fisher BRAHMS, HyTest Ltd., Biomedica, Abbott Diagnostics, Novartis, Singulex, SomaLogic, and Roche Diagnostics. T. O. also has financial interests in Cardinor AS, which holds the license to commercialize secretoneurin. Waleed Ghanima reports fees for participation in Advisory board from Amgen, Novartis, Pfizer, Principia Biopharma Inc- a Sanofi Company, Sanofi, SOBI, Grifols, UCB, Argenx, Cellphire. Lecture honoraria from Amgen, Novartis, Pfizer, Bristol Myers Squibb, SOBI, Grifols, Sanofi, and Bayer, and have received research grants from Bayer, BMS/Pfizer, and UCB. All other authors report no disclosures.
Serum PM20D1 levels in patients with idiopathic pulmonary arterial hypertension and its clinical significance.
Serum PM20D1 levels in patients with idiopathic pulmonary arterial hypertension and its clinical significance.
Fuente:Bmc Cardiovascular Disorders
Extracto:
Our
findings indicated that the serum levels of PM20D1 were significantly decreased
in IPAH patients with poor prognosis. Moreover, PM20D1 was identified as a risk
factor associated with mortality in IPAH patients.
institución:(a) Department of Respiratory and Critical Care Medicine, Zhuzhou Hospital Affiliated to Xiangya School of Medicine, Central South University, Zhuzhou, 412000, Hunan Province, P.R. China. (b) Department of Cardiology, Zhuzhou Hospital Affiliated to Xiangya School of Medicine, Central South University, Zhuzhou, 412000, Hunan Province, P.R. China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Extensive surgical resections for rare pleural neoplasms: a single-center experience with a yolk sac tumor and synovial sarcoma.
Extensive surgical resections for rare pleural neoplasms: a single-center experience with a yolk sac tumor and synovial sarcoma.
Fuente:World Journal of Surgical Oncology
Extracto:
Neo-adjuvant
chemotherapy followed by extensive thoracic surgery, including hyperthermic
intrathoracic chemotherapy, is a feasible treatment strategy for non-mesothelioma
primary pleural neoplasms, but careful follow-up is required.
Autor/es:Vandaele, Tom (a) Van Slambrouck, Jan (b)
institución:(a) Department of Thoracic Surgery, University Hospitals Leuven, Leuven, Belgium. vandaeletom@live.be. (b) Department of Chronic Diseases and Metabolism, Laboratory of Respiratory Diseases and Thoracic Surgery (BREATHE), KU Leuven, Leuven, Belgium. vandaeletom@live.be.
Euro surveillance bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin
Selección SIIC: 18 Abril, 2024
Euro surveillance bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin
Excess mortality in Europe coincides with peaks of COVID-19, influenza and respiratory syncytial virus (RSV), November 2023 to February 2024.
Excess mortality in Europe coincides with peaks of COVID-19, influenza and respiratory syncytial virus (RSV), November 2023 to February 2024.
Fuente:Euro Surveillance Bulletin Europeen Sur Les Maladies Transmissibles = European Communicable Disease Bulletin
Extracto:
This excess mortality is seen in adults aged 45 years and older, and
coincides with widespread presence of COVID-19, influenza and respiratory
syncytial virus (RSV) observed in many European countries during the 2023/24
winter season.
institución:(a) Department of Infectious Disease Epidemiology and Prevention, Statens Serum Institut, Copenhagen, Denmark. (b) Department of Infectious Disease Epidemiology and Prevention, Statens Serum Institut, Copenhagen, Denmark.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Association between neck circumference and pulmonary function in Korean adults.
Association between neck circumference and pulmonary function in Korean adults.
Fuente:Medicine
Extracto:
Understanding this relationship can inform preventive
strategies and interventions to improve the respiratory health of individuals
with central obesity.
institución:(a) Department of Family Medicine, Gil Medical Center, Gachon University College of Medicine, Incheon, Republic of Korea. (b) Department of Family Medicine, Veterans Health Service Medical Center, Seoul, Republic of Korea.
Conflicto:The authors have no funding and conflicts of interest to disclose.
Effectiveness and safety of remimazolam combined with alfentanil in hysteroscopic examination: A prospective, randomized, single-blind trial.
Effectiveness and safety of remimazolam combined with alfentanil in hysteroscopic examination: A prospective, randomized, single-blind trial.
Fuente:Medicine
Extracto:
In
hysteroscopy, the sedative effect of remimazolam is like that of propofol, with
0.25 mg/kg remimazolam showing better safety and efficacy, and less impact on the
respiratory and circulatory systems. Additionally, under the influence of
alfentanil, the ED50 of remimazolam in hysteroscopy is 0.244 mg/kg, with no
severe adverse reactions observed.
institución:(a) The Affiliated Nanhua Hospital, Hengyang Medical School, University of South China, Hengyang, Hunan, China. (b) The Affiliated Nanhua Hospital, Department of Anesthesiology, Hengyang Medical School, University of Suth China, Hengyang, Hunan, China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación