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Impact of 1-Year Supplementation with High-Rich Docosahexaenoic Acid (DHA) on Clinical Variables and Inflammatory Biomarkers in Pediatric Cystic Fibrosis: A Randomized Double-Blind Controlled Trial.
Impact of 1-Year Supplementation with High-Rich Docosahexaenoic Acid (DHA) on Clinical Variables and Inflammatory Biomarkers in Pediatric Cystic Fibrosis: A Randomized Double-Blind Controlled Trial.
Fuente:Nutrients
Extracto:
In summary, the use of a highly
concentrated DHA supplement for 1 year as compared with placebo improved
pulmonary function and reduced exacerbations in pediatric CF.
Improvement of Lung Function by Micronutrient Supplementation in Patients with COPD
Improvement of Lung Function by Micronutrient Supplementation in Patients with COPD
Fuente:Nutrients
Tipo de trabajo:Revisión sistemática
Extracto:
Micronutrient supplementation,
such as vitamin D alone and compound nutrients, has improved effect on the lung
function of patients with COPD. Therefore, proper supplementation with
micronutrients would be beneficial to stabilize the condition and restore
ventilation function for COPD patients.
institución:(a) School of Public Health, Qingdao University, Qingdao 266000, China. (b) School of Public Health, Qingdao University, Qingdao 266000, China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
The prevalence of acute kidney injury in patients with community-acquired pneumonia who required mechanical ventilation.
The prevalence of acute kidney injury in patients with community-acquired pneumonia who required mechanical ventilation.
Fuente:Annals of Saudi Medicine
Extracto:
Among
mechanically ventilated patients with CAP, AKI was common and was associated with
higher crude mortality. The higher mortality could not be attributed alone to
AKI, but rather appeared to be related to multi-organ dysfunction. LIMITATIONS:
Single-center retrospective study with no data on baseline serum creatinine and
the use of estimated baseline creatinine distributions based on the MDRD
(Modification of Diet in Renal Disease)equation which may lead to an
overestimation of AKI. Second, we did not have data on the microbiology of
pneumonia, appropriateness of antibiotic therapy or the administration of other
medications that have been demonstrated to be associated with AKI.
Cita:Ann Saudi Med 2024 Mar-Apr; 44 (2) : 104-110.
institución:(a) From the Intensive Care Department, College of Medicine, King Saud bin Abdulaziz University for Health Sciences, King Abdulaziz Medical City, Riyadh, Saudi Arabia. (b) From the Intensive Care Department, College of Medicine, King Saud bin Abdulaziz University for Health Sciences, King Abdulaziz Medical City, Riyadh, Saudi Arabia.
The Outcomes of Patients with Omicron Variant Infection who Undergo Elective Surgery: A Propensity-score-matched Case-control Study.
The Outcomes of Patients with Omicron Variant Infection who Undergo Elective Surgery: A Propensity-score-matched Case-control Study.
Fuente:International Journal of Medical Sciences
Extracto:
The Omicron infection may not be a sufficient risk factor to postpone elective
surgery.
Claves:Omicron variant, postoperative complications, timing of surgery
Cita:Int J Med Sci 2024; 21 (5) : 817-825.
Autor/es:Xiong, Xiaojuan (a) Li, Rui (b)
institución:(a) Department of Anesthesiology, Army Medical Center of PLA, Daping Hospital, Army Medical University, 10 ChangjiangZhilu, Yuzhong District, Chongqing 400042, China. (b) Department of Anesthesiology, Army Medical Center of PLA, Daping Hospital, Army Medical University, 10 ChangjiangZhilu, Yuzhong District, Chongqing 400042, China.
Conflicto:Competing Interests: The authors have declared that no competing interest exists.
Extracto:
This
article aims to review community-acquired respiratory illnesses covering a broad
spectrum of viruses, bacteria, and atypical microorganisms and focuses on the
cluster prevalence of multiple known respiratory pathogens in China, thereby
providing effective prevention and control measures.
institución:(a) Tianjin Institute of Urology, The Second Hospital of Tianjin Medical University, Tianjin 300211, China. (b) Tianjin Institute of Urology, The Second Hospital of Tianjin Medical University, Tianjin 300211, China.
Conflicto:Competing Interests: The authors have declared that no competing interest exists.
Long-Term SGRQ Stability in a Cohort of Individuals with Alpha-1 Antitrypsin Deficiency-Associated Lung Disease.
Long-Term SGRQ Stability in a Cohort of Individuals with Alpha-1 Antitrypsin Deficiency-Associated Lung Disease.
Fuente:International Journal of Chronic Obstructive Pulmonary Disease
Extracto:
We observed long-term
stability in HRQoL and an association between the rate of change in SGRQ and
baseline mMRC, exacerbation frequency, productive cough, and use of oxygen in
this cohort of individuals with AATD-associated lung disease.
Claves:COPD, alpha-1 antitrypsin deficiency, quality of life
institución:(a) University of Kentucky College of Public Health, Lexington, Kentucky, USA. (b) Department of Medicine, National Jewish Health, Denver, Colorado, USA.
Conflicto:Dr Radmila Choate reports research support for AlphaNet. Dr Kristen Holm is affiliated with AlphaNet and reports personal fees from AlphaNet, outside the submitted work. Dr Robert Sandhaus is affiliated with AlphaNet and reports contract payments to AlphaNet, Inc. for Disease Management Services from Grifols and CSL Behring; grants to AlphaNet for Disease Management Services from Takeda, grants from Vertex...
for investigations in multicenter clinical trial at National Jewish Health and Inhibrx. In addition, he is also the data monitoring committee member for Takeda Alpha-1 liver therapy trial, advisory committee member for Grifols, CSL Behring, Beam, Kooro Bio, Intellia, ADARx, ARespo, Evolve, and Vertex. Some of these companies paid travel expenses. Dr David Mannino reports personal fees from AstraZeneca, GlaxoSmithKline, Regeneron, and Genentech, outside the submitted work. Dr Charlie Strange is a medical director of AlphaNet and reports personal fees and/or non-financial support from AlphaNet and Inhibrx. He also reports grants/personal fees from Grifols, Takeda, CSL Behring, Dicerna, from Inhibrx, and Vertex, outside the submitted work. The authors report no other conflicts of interest in this work.
Indoor environmental quality in schools: NOTECH solution vs. standard solution.
Indoor environmental quality in schools: NOTECH solution vs. standard solution.
Fuente:F1000research
Extracto:
While the performance of the both systems complies to the Danish Building
Regulations, the indoor environmental quality between systems differs
significantly. Results showing a higher air-temperature and lower relative
air-humidity in the classroom with mechanical ventilation during winter and lower
CO (2) levels in the mechanically ventilated classroom during winter and summer.
Costs for implementation, energy consumption for heating and CO (2) footprint for
building materials are significantly lower for the NOTECH solution, compared to
the mechanical solution.
institución:(a) NID-Group, Copenhagen University Hospital, Copenhagen, Frederiksberg, 2000, Denmark. (b) NID-Group, Copenhagen University Hospital, Copenhagen, Frederiksberg, 2000, Denmark.
Conflicto:Competing interests: The system in the study was tested and developed in an independent research project at Skovbrynet Skole. Later on, the NOTECH solution was further improved and the authors C Volf together with Danish Techno-logical Institute (DTI) implemented it at a new school project and won a Danish Design Award 2021 in the category Better Learning. In this process...
and in the later development of the system, WindowMaster was a commercial part. The timeline for this development process and the study is independent, and data and conclusions only refer to the study at Skovbrynet Skole.
institución:(a) Department of Hepatobiliary Surgery, The First Affiliated Hospital, Xi'an Jiaotong University, Xi'an, Shaanxi, China. (b) Department of Hepatobiliary Surgery, The First Affiliated Hospital, Xi'an Jiaotong University, Xi'an, Shaanxi, China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Physiologically based modeling reveals different risk of respiratory depression after fentanyl overdose between adults and children.
Physiologically based modeling reveals different risk of respiratory depression after fentanyl overdose between adults and children.
Fuente:Clinical and Translational Science
Extracto:
Our work indicates that when developing intervention
strategies to protect children from opioid overdose in a community setting, these
pediatric-specific factors may need to be considered.
institución:(a) Division of Applied Regulatory Science, Office of Clinical Pharmacology, Office of Translational Sciences, Center for Drug Evaluation and Research, Food and Drug Administration, Silver Spring, Maryland, USA. (b) Division of Applied Regulatory Science, Office of Clinical Pharmacology, Office of Translational Sciences, Center for Drug Evaluation and Research, Food and Drug Administration, Silver Spring, Maryland, USA.
Conflicto:The authors declare no competing interest for this work.
Gut-Lung Microbiota Characterization in Patients with Non-Small Cell Lung Carcinoma and COVID-19 Coinfection.
Gut-Lung Microbiota Characterization in Patients with Non-Small Cell Lung Carcinoma and COVID-19 Coinfection.
Fuente:Archives of Iranian Medicine
Extracto:
Eventually, it was found that compared to control groups, COVID-19 patients with
NSCLC showed diminished gut bacteria diversity and increase in Lactobacillus
spp., A. muciniphila, and Bifidobacterium spp. The overgrowth of Enterococcus
spp., Streptococcus spp., and Prevotella spp. could be potential predictive
biomarkers in the gut-lung axis of NSCLC patients with COVID-19.
institución:(a) Infectious Diseases and Tropical Medicine Research Center, Isfahan University of Medical Sciences, Isfahan, Iran. (b) Nosocomial Infection Research Center, Isfahan University of Medical Sciences, Isfahan, Iran.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Influencing factors of good quality of life among chronic obstructive pulmonary disease patients living in Zhejiang Province, China.
Influencing factors of good quality of life among chronic obstructive pulmonary disease patients living in Zhejiang Province, China.
Fuente:Scientific Reports
Extracto:
Increasing family income and implementing
measures to improve the accessibility of medical care, including developing a
proper system to decrease the cost of treatment for COPD patients, can improve
patients' QOL.
institución:(a) School of Health Science, Mae Fah Luang University, 333 Moo 1, Ta Sud Subdistrict, Muang District, 57100, Chiang Rai Province, Thailand. (b) School of Health Science, Mae Fah Luang University, 333 Moo 1, Ta Sud Subdistrict, Muang District, 57100, Chiang Rai Province, Thailand. siriyaporn.khu@mfu.ac.th.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Modulate the impact of the drowsiness on the resting state functional connectivity.
Modulate the impact of the drowsiness on the resting state functional connectivity.
Fuente:Scientific Reports
Extracto:
These findings bear
resemblance to the anticipated patterns during the onset of sleep, where the
cortex isolates itself to assist in transitioning into deeper slow wave sleep
phases, simultaneously disconnecting the DMN.
Body composition impacts outcome of bronchoscopic lung volume reduction in patients with severe emphysema: a fully automated CT-based analysis.
Body composition impacts outcome of bronchoscopic lung volume reduction in patients with severe emphysema: a fully automated CT-based analysis.
Fuente:Scientific Reports
Extracto:
Altered body composition,
especially increased muscle volume, is associated with functional improvements in
BLVR-treated patients.
Claves:Artificial intelligence, Body composition, Bronchoscopic lung volume reduction, Chronic obstructive pulmonary disease, Computed tomography, Deep learning, Emphysema, Valves
Cita:Sci Rep 2024 Apr 15; 14 (1) : 8718.
Autor/es:Wienker, Johannes (a) Darwiche, Kaid (b)
institución:(a) Division of Interventional Pneumology, Department of Pulmonary Medicine, University Medicine Essen-Ruhrlandklinik, Tüschener Weg 40, 45239, Essen, Germany. johannes.wienker@rlk.uk-essen.de. (b) Division of Interventional Pneumology, Department of Pulmonary Medicine, University Medicine Essen-Ruhrlandklinik, Tüschener Weg 40, 45239, Essen, Germany.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
The Fractional exhaled Nitric Oxide (FeNO)- test as add-on test in the diagnostic work-up of asthma: a study protocol.
The Fractional exhaled Nitric Oxide (FeNO)- test as add-on test in the diagnostic work-up of asthma: a study protocol.
Fuente:Bmc Pulmonary Medicine
Tipo de trabajo:Guía
Extracto:
The FeNO-test can be used
to rule in a diagnosis of asthma with confidence, however, due to the poor
sensitivity it is not suitable to rule out asthma.
Autor/es:Kaya, T Tuba (a) Braunstahl, G J Gert-Jan (b)
institución:(a) Department of Pulmonary Diseases, Center of Excellence for asthma, COPD and respiratory allergy, Franciscus Gasthuis & Vlietland, P.O. box 3045 PM, Rotterdam, The Netherlands. (b) Department of Pulmonary Diseases, Center of Excellence for asthma, COPD and respiratory allergy, Franciscus Gasthuis & Vlietland, P.O. box 3045 PM, Rotterdam, The Netherlands.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Critically ill children with SARS-COV-2 Omicron infection at a national children medical center, Guangdong, China.
Critically ill children with SARS-COV-2 Omicron infection at a national children medical center, Guangdong, China.
Fuente:Bmc Pediatrics
Extracto:
We present a case series of
critically ill children infected with the SARS-CoV-2 omicron variant. While there
is evidence suggesting that Omicron may cause less severe symptoms, it is
important to continue striving for measures that can minimize the pathogenic
impact of SARS-CoV-2 infection in children.
institución:(a) Precision Medical Lab Center, Chaozhou Central Hospital, Chaozhou, Guangdong Province, P. R. China. (b) Department of Allergy, Immunology and Rheumatology, Guangzhou Women and Children's Medical Center, Guangdong Province, P. R. China.
Conflicto:The authors have no relevant financial or non-financial interests to disclose.
Inflammation mediates the association between furan exposure and the prevalence and mortality of chronic obstructive pulmonary disease: National Health and Nutrition Examination Survey 2013-2018.
Inflammation mediates the association between furan exposure and the prevalence and mortality of chronic obstructive pulmonary disease: National Health and Nutrition Examination Survey 2013-2018.
Fuente:Bmc Public Health
Extracto:
Exposure to furan demonstrates a positive correlation with both the
prevalence and respiratory mortality of COPD, with inflammation identified as a
crucial mediator in this relationship.
Cita:BMC Public Health 2024 Apr 15; 24 (1) : 1046.
Autor/es:Sun, Di (a) Wang, Yuanying (b)
institución:(a) Department of Occupational Medicine and Toxicology, Clinical Center for Interstitial Lung Diseases, Beijing Institute of Respiratory Medicine, Beijing Chao-Yang Hospital, Capital Medical University, 100020, Beijing, China. (b) Department of Occupational Medicine and Toxicology, Clinical Center for Interstitial Lung Diseases, Beijing Institute of Respiratory Medicine, Beijing Chao-Yang Hospital, Capital Medical University, 100020, Beijing, China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Based on molecular docking and real-time PCR technology, the two-component system Bae SR was investigated on the mechanism of drug resistance in CRAB.
Based on molecular docking and real-time PCR technology, the two-component system Bae SR was investigated on the mechanism of drug resistance in CRAB.
Fuente:Bmc Microbiology
Extracto:
baumannii.
Claves:Acinetobacter baumannii, Carbapenemase, Molecular docking, Two-component system
Cita:BMC Microbiol 2024 Apr 15; 24 (1) : 126.
Autor/es:Pan, Beizhen (a) Wang, Yuefeng (b)
institución:(a) School of Medical Technology, Beihua University, No. 3999 Binjiang East Road, Fengman District, Jilin, Jilin Province, China. (b) School of Medical Technology, Beihua University, No. 3999 Binjiang East Road, Fengman District, Jilin, Jilin Province, China.
Human genetic associations of the airway microbiome in chronic obstructive pulmonary disease.
Human genetic associations of the airway microbiome in chronic obstructive pulmonary disease.
Fuente:Respiratory Research
Extracto:
These
results suggest a previously underappreciated role of host genetics in shaping
the airway microbiome and provide fresh hypotheses for genetic-based
host-microbiome interactions in COPD.
institución:(a) Institute of Ecological Sciences, School of Life Sciences, South China Normal University, Guangzhou, Guangdong Province, China. (b) State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, National Center for Respiratory Medicine, Guangzhou Institute of Respiratory Health, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong Province, China.
Effects of right ventricular remodeling in chronic thromboembolic pulmonary hypertension on the outcomes of balloon pulmonary angioplasty: a 2D-speckle tracking echocardiography study.
Effects of right ventricular remodeling in chronic thromboembolic pulmonary hypertension on the outcomes of balloon pulmonary angioplasty: a 2D-speckle tracking echocardiography study.
Fuente:Respiratory Research
Extracto:
BPA was found to reduce pulmonary artery pressure, reverse RV
remodeling, and improve exercise capacity. RVFWLS obtained by 2D-STE was an
independent predictor of BPA outcomes. Our study may provide a meaningful
reference for interventional therapy of CTEPH.
Claves:Balloon pulmonary angioplasty, Chronic thromboembolic pulmonary hypertension, Predictor, Right ventricular free wall longitudinal strain, Right ventricular remodeling
Cita:Respir Res 2024 Apr 15; 25 (1) : 164.
Autor/es:Ma, Yaning (a) Guo, Dichen (b)
institución:(a) Department of Ultrasound Medicine, Beijing Chao-Yang Hospital, Capital Medical University, 8 Gongren Tiyuchang Nanlu, Chaoyang District, Beijing, 100020, China. (b) Department of Ultrasound Medicine, Beijing Chao-Yang Hospital, Capital Medical University, 8 Gongren Tiyuchang Nanlu, Chaoyang District, Beijing, 100020, China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Anti-synthase syndrome associated with SARS-Cov-2 infection.
Anti-synthase syndrome associated with SARS-Cov-2 infection.
Fuente:Bmc Pulmonary Medicine
Extracto:
This case
presents an early diagnosis and successful treatment of anti-synthetase syndrome
combined with SARS-Cov-2 infection, emphasizing the importance of comprehensive
physical examination. Additionally, it highlights the rapid progression of
interstitial lung disease under SARS-Cov-2 infection, which is often difficult to
distinguish on imaging. In cases where treatment for SARS-Cov-2 infection is
ineffective, early screening for autoimmune diseases is recommended. As there is
currently no standardized method for treating AS-ILD, the successful treatment of
this case provides a reference for clinical research on anti-synthetase syndrome
in the later stage.
institución:(a) Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, 610,032, China. (b) Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, 610,032, China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación