Influence of vaccination on critical COVID-19 patients with acute respiratory failure

Influence of vaccination on critical COVID-19 patients with acute respiratory failure

Fuente:European Journal of Medical Research

Tipo de trabajo:Estudio de cohortes

Extracto: Vaccination status did not significantly influence mortality rates, the occurrence of ARDS, or the viral shedding duration in COVID-19 patients with acute respiratory failure.

Claves:Acute Respiratory Distress Syndrome, Acute Respiratory Failure, COVID-19 Vaccines, Coronavirus Disease 2019 (COVID-19), Virus Shedding

Cita:Eur J Med Res 2024 Apr 20; 29 (1) : 243.

Autor/es:Shen, Hsiao-Chin (a)
Huang, Jhong-Ru (b)

institución:(a) Department of Chest Medicine, Taipei Veterans General Hospital, #201, Sec. Shih-Pai Road, Taipei, 11217, Taiwan.
(b) School of Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1186/s40001-024-01840-5

The effect of immunosuppressive therapies on the endothelial host response in critically ill COVID-19 patients.

The effect of immunosuppressive therapies on the endothelial host response in critically ill COVID-19 patients.

Fuente:Scientific Reports

Extracto: These results increase the understanding of the mechanisms of interventions and are possibly useful for stratification of patients with other inflammatory conditions which may potentially benefit from these treatments.

Claves:COVID-19, Coagulation, Complement, Endothelial function, Host response, Immunomodulatory treatment

Cita:Sci Rep 2024 Apr 20; 14 (1) : 9113.

Autor/es:Slim, M A (a)
Lim, E H T (b)

institución:(a) Center for Experimental and Molecular Medicine, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, The Netherlands. m.a.slim@amsterdamumc.nl.
(b) Department of Intensive Care, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, The Netherlands. m.a.slim@amsterdamumc.nl.

Conflicto:LvV was supported by the Netherlands Organisation for Health Research and Development ZonMW (Nederlandse Organisatie voor Wetenschappelijk Onderzoek NWO) VENI Grant 09150161910033 and the European Society of Clinical Microbiology and Infectious Diseases (ESCMID) Research Grant. AV received consulting fees from InflaRx paid to the institution. LD is supported by grants payed to UMCU for REMAP-CAP (FP7 PREPARE Grant No. 602525; H2020 RECOVER Grant No.... No. 101003589; H2020 ECRAID-Base Grant No. 965313). MS, EL, ATB, ER, JHM, JE, PP, FvDV and NJ have no COI related to this study.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1038/s41598-024-59385-w

The changing epidemiology of pulmonary infection in children and adolescents with cystic fibrosis: an 18-year experience.

Fuente:Scientific Reports

Extracto: There is a shift in CF among respiratory pathogens and prescriptions which reflects the evolution of cystic fibrosis treatment strategies over time.

Cita:Sci Rep 2024 Apr 20; 14 (1) : 9056.

Autor/es:Singh, Jagdev (a)
Hunt, Sharon (b)

institución:(a) Department of Respiratory Medicine, The Children's Hospital at Westmead, Sydney, NSW, Australia. Jagdev.singh@health.nsw.gov.au.
(b) Department of Pharmacy, The Children's Hospital at Westmead, Sydney, NSW, Australia. Jagdev.singh@health.nsw.gov.au.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1038/s41598-024-59658-4

Deviations in RSV epidemiological patterns and population structures in the United States following the COVID-19 pandemic.

Deviations in RSV epidemiological patterns and population structures in the United States following the COVID-19 pandemic.

Fuente:Nature Communications

Extracto: Mutations in the antigenic regions of the fusion protein suggest convergent evolution with potential implications for vaccine and therapeutic development.

Cita:Nat Commun 2024 Apr 20; 15 (1) : 3374.

Autor/es:Rios-Guzman, Estefany (a)
Simons, Lacy M (b)

institución:(a) Division of Infectious Diseases, Northwestern University Feinberg School of Medicine, Chicago, IL, 60611, USA.
(b) Center for Pathogen Genomics and Microbial Evolution, Northwestern University Havey Institute for Global Health, Chicago, IL, 60611, USA.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1038/s41467-024-47757-9

Assisted reproductive techniques and subsequent risk of asthma and allergic rhinitis in offspring

Assisted reproductive techniques and subsequent risk of asthma and allergic rhinitis in offspring

Fuente:European Review For Medical and Pharmacological Sciences

Tipo de trabajo:Estudio de cohortes

Extracto: Our study offers important insights for clinicians, researchers, and parents regarding the health outcomes of ART-conceived infants and enhances our understanding of ART's impact on respiratory health.

Cita:Eur Rev Med Pharmacol Sci 2024 Apr; 28 (7) : 2737-2749.

Autor/es:Kim, S H (a)
Kim, M (b)

institución:Kim, S H (a)
Kim, M (b)

Formato:Informe impreso

Idioma:Inglés

País de fuente:Italia

Sitio web:http://dx.doi.org/10.26355/eurrev_202404_35902

Reconstruction method for massive lateral chest wall sarcoma using titanium plates and mesh

Reconstruction method for massive lateral chest wall sarcoma using titanium plates and mesh

Fuente:Journal of Cardiothoracic Surgery

Tipo de trabajo:Caso clínico

Extracto: In this case, the combination of a titanium plate and a Gore-Tex patch proved effective for reconstructing massive lateral chest wall defects. The approach provided stability, preserved thoracic volume, and allowed for lateral mobility. While the patient achieved a successful outcome in terms of local recurrence and respiratory function, distant metastasis remained a challenge for myxofibrosarcoma patients, and its impact on long-term prognosis requires further investigation. Nevertheless, the described procedure offers promise for managing extensive chest wall defects.

Claves:Case report, Chest wall tumor surgery, Gore-Tex patch, Myxofibrosarcoma, Titanium plate

Cita:J Cardiothorac Surg 2024 Apr 18; 19 (1) : 245.

Autor/es:Tanaka, Shin (a)
Nakata, Eiji (b)

institución:(a) Department of General Thoracic Surgery and Breast and Endocrinological Surgery, Dentistry, and Pharmaceutical Sciences, Okayama University Graduate School of Medicine, Okayama, Japan.
(b) Department of Orthopedic Surgery, Dentistry, and Pharmaceutical Sciences, Okayama University Graduate School of Medicine, 2-5-1, Shikata-cho, Kita-ku, Okayama, 700-8558, Japan. eijinakata8522@yahoo.co.jp.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1186/s13019-024-02639-5

Comorbidities and their association with COVID-19 mortality in Mexico between January 2020 and August 2021.

Comorbidities and their association with COVID-19 mortality in Mexico between January 2020 and August 2021.

Fuente:Plos One

Extracto: Intensive care unit (ICU), patient intubation, and pneumonia diagnosis are shown to substantially increase mortality risk for COVID-19 patients.

Cita:PLoS One 2024; 19 (4) : e0296895.

Autor/es:Lowhorn, Ryan J (a)
Chowdhury, Mohammed (b)

institución:(a) School of Data Science and Analytics, Kennesaw State University, Kennesaw, Georgia, United States of America.
(b) College of Business and Technology, Western Illinois University, Macomb, Illinois, United States of America.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:EE.UU.

Sitio web:http://dx.doi.org/10.1371/journal.pone.0296895

Gestational and neonatal outcomes of women with partial Dunnigan lipodystrophy.

Gestational and neonatal outcomes of women with partial Dunnigan lipodystrophy.

Fuente:Frontiers in Endocrinology

Tipo de trabajo:Revisión

Extracto: Our data showed a high frequency of fetal complications in women with FPLD2. However, no instances of infertility or prolonged attempts to conceive have been reported, highlighting the significance of employing effective contraception strategies to plan pregnancies at optimal times for managing metabolic comorbidities.

Claves:Dunnigan, FPLD2, gestational diabetes mellitus, lipodystrophy, pregnancy

Cita:Front Endocrinol (Lausanne) 2024; 15 : 1359025.

Autor/es:Valerio, Cynthia M (a)
Muniz, Raquel Beatriz Gonçalves (b)

institución:(a) Department of Metabolism, Institute of Diabetes and Endocrinology of Rio de Janeiro (IEDE), Rio de Janeiro, Brazil.
(b) Brazilian Group for the Study of Inherited and Acquired Lipodystrophies (BRAZLIPO), Fortaleza, Brazil.

Conflicto:The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3389/fendo.2024.1359025

The predictive power of data: machine learning analysis for Covid-19 mortality based on personal, clinical, preclinical, and laboratory variables in a case-control study.

The predictive power of data: machine learning analysis for Covid-19 mortality based on personal, clinical, preclinical, and laboratory variables in a case-control study.

Fuente:Bmc Infectious Diseases

Extracto: This study highlights the potential of ML analysis to improve the accuracy of COVID-19 mortality prediction and emphasizes the need for a comprehensive approach that considers multiple feature categories. It highlights the critical role of data quality and quantity in improving model performance and contributes to our understanding of the multifaceted factors that influence COVID-19 outcomes.

Claves:Coronavirus disease, Data quality, Machine learning, Performance, Predictive model

Cita:BMC Infect Dis 2024 Apr 18; 24 (1) : 411.

Autor/es:Seyedtabib, Maryam (a)
Najafi-Vosough, Roya (b)

institución:(a) Department of Biostatistics and Epidemiology, School of Health, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.
(b) Research Center for Health Sciences, Hamadan University of Medical Sciences, Hamadan, Iran.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1186/s12879-024-09298-w

The use of late preterm antenatal corticosteroids in women with gestational diabetes a puzzle worth solving.

The use of late preterm antenatal corticosteroids in women with gestational diabetes a puzzle worth solving.

Fuente:Bmc Pregnancy and Childbirth

Tipo de trabajo:Estudio de cohortes

Extracto: Antenatal corticosteroid treatment at or after 34 0/7 weeks of gestation in women with gestational diabetes mellitus who had a late preterm delivery was not associated with improvement in adverse neonatal outcomes. Decreasing gestational age at birth was the only independent risk factor predicting composite neonatal and composite respiratory outcomes.

Claves:Antenatal corticosteroids, Gestational diabetes mellitus, Hyperbilirubinemia, Late preterm, Neonatal outcome

Cita:BMC Pregnancy Childbirth 2024 Apr 18; 24 (1) : 286.

Autor/es:Özkan, Sadullah (a)
Dereli, Murat Levent (b)

institución:(a) Department of Obstetrics and Gynecology, Division of Perinatology, Ankara Etlik Lady Zübeyde Maternity and Women's Health Teaching and Research Hospital, P.O. box 06010, New Etlik Street No:55 Etlik, Keçiören, Ankara, Turkey. sadullahozkan@gmail.com.
(b) Department of Obstetrics and Gynecology, Division of Perinatology, Ankara Etlik Lady Zübeyde Maternity and Women's Health Teaching and Research Hospital, P.O. box 06010, New Etlik Street No:55 Etlik, Keçiören, Ankara, Turkey.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1186/s12884-024-06510-2

The activity and immune dynamics of PD-1 inhibition on high-risk pulmonary ground glass opacity lesions: insights from a single-arm, phase II trial.

Fuente:Signal Transduction and Targeted Therapy

Extracto: Such effects were associated with specific T-cell re-distribution, EGF/CTLA-4 cytokine compensation, and regulation of metabolism pathways.

Cita:Signal Transduct Target Ther 2024 Apr 19; 9 (1) : 93.

Autor/es:Cheng, Bo (a)
Li, Caichen (b)

institución:(a) Department of Thoracic Surgery and Oncology, the First Affiliated Hospital of Guangzhou Medical University, Guangzhou Institute of Respiratory Health, State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou, China.
(b) Department of Thoracic Surgery and Oncology, the First Affiliated Hospital of Guangzhou Medical University, Guangzhou Institute of Respiratory Health, State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou, China.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1038/s41392-024-01799-z

Impact of insertion into the left internal jugular vein in chemoport-associated infections: a retrospective single-center study of 1690 cases.

Impact of insertion into the left internal jugular vein in chemoport-associated infections: a retrospective single-center study of 1690 cases.

Fuente:Scientific Reports

Extracto: Using the right internal jugular vein rather than the left internal jugular vein when performing chemoport insertion might reduce subsequent infections.

Claves:Chemoport, Infection, Internal jugular vein

Cita:Sci Rep 2024 Apr 18; 14 (1) : 8925.

Autor/es:Kim, Gwon-Min (a)
Song, Seunghwan (b)

institución:(a) Medical Research Institute, Pusan National University, Busan, Republic of Korea.
(b) Department of Thoracic and Cardiovascular Surgery, Pusan National University School of Medicine, Biomedical Research Institute, Pusan National University Hospital, Busan, Republic of Korea.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1038/s41598-024-59749-2

Potential application of mesenchymal stromal cells as a new therapeutic approach in acute respiratory distress syndrome and pulmonary fibrosis.

Potential application of mesenchymal stromal cells as a new therapeutic approach in acute respiratory distress syndrome and pulmonary fibrosis.

Fuente:Respiratory Research

Extracto: Although further investigations and shared protocols are still needed, the safety of MSC therapy has been recurrently shown, and its potential in treating ARDS and preventing PF might represent a new therapeutic strategy.

Claves:ARDS, Acute respiratory distress syndrome, COVID-19, Mesenchymal stromal cells, Pulmonary fibrosis

Cita:Respir Res 2024 Apr 18; 25 (1) : 170.

Autor/es:Gazzaniga, Giulia (a)
Voltini, Marta (b)

institución:(a) SC Anestesia e Rianimazione 2, Fondazione IRCCS Policlinico San Matteo, Viale Camillo Golgi 19, Pavia, PV, 27100, Italy. giulia.gazzaniga@libero.it.
(b) Department of Clinical-Surgical, Diagnostic and Pediatric Sciences, University of Pavia, Pavia, Italy. giulia.gazzaniga@libero.it.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1186/s12931-024-02795-1

Tumor lymphangiogenesis index reveals the immune landscape and immunotherapy response in lung adenocarcinoma.

Tumor lymphangiogenesis index reveals the immune landscape and immunotherapy response in lung adenocarcinoma.

Fuente:Frontiers in Immunology

Extracto: Overall, we confirmed that the LYM index is a prognostic risk factor and a valuable predictor of immunotherapy response in LUAD patients, which provides new evidence for the potential application of LYM.

Claves:immune cell infiltration, immunotherapy, lung adenocarcinoma, lymphangiogenesis, prognosis

Cita:Front Immunol 2024; 15 : 1354339.

Autor/es:Yang, Weichang (a)
Wu, Zhijian (b)

institución:(a) Department of Respiratory and Critical Care Medicine, The Second Affiliated Hospital of Nanchang University, Jiangxi Medical College, Nanchang University, Nanchang, Jiangxi, China.
(b) Jiangxi Key Laboratory of Molecular Medicine, Nanchang, Jiangxi, China.

Conflicto:The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3389/fimmu.2024.1354339

Systemic immune-inflammation index and all-cause and cause-specific mortality in sarcopenia: a study from National Health and Nutrition Examination Survey 1999-2018.

Fuente:Frontiers in Immunology

Extracto: Our study is the first to demonstrate a significant relationship between SII and increased mortality risks in a sarcopenia population.

Claves:NHANES, mortality, population-based study, sarcopenia, systemic immune-inflammation index

Cita:Front Immunol 2024; 15 : 1376544.

Autor/es:Zeng, Qing-Yue (a)
Qin, Yu (b)

institución:(a) General Practice Ward/International Medical Center Ward, General Practice Medical Center, National Clinical Research Center for Geriatrics, West China Hospital, Sichuan University, Chengdu, Sichuan, China.
(b) General Practice Ward/International Medical Center Ward, General Practice Medical Center, National Clinical Research Center for Geriatrics, West China Hospital, Sichuan University, Chengdu, Sichuan, China.

Conflicto:The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3389/fimmu.2024.1376544

The safety signal detection and analysis of monoclonal antibodies against SARS-CoV-2 based on real-world evidence - the suitable selectivity for different populations.

The safety signal detection and analysis of monoclonal antibodies against SARS-CoV-2 based on real-world evidence - the suitable selectivity for different populations.

Fuente:European Review For Medical and Pharmacological Sciences

Extracto: In summary, SOT may be unsuitable for allergic patients and may lead to abnormal test results. BEB showed the highest correlations with gastrointestinal and neuropsychiatric events. In addition, its infusion reactions should also be noted. TIX/CIL can lead to a variety of cardiovascular events.

Cita:Eur Rev Med Pharmacol Sci 2024 Apr; 28 (7) : 2943-2954.

Autor/es:Wang, Y (a)
Xu, X-W (b)

institución:Wang, Y (a)
Xu, X-W (b)

Formato:Informe impreso

Idioma:Inglés

País de fuente:Italia

Sitio web:http://dx.doi.org/10.26355/eurrev_202404_35925

Cost-utility analysis of palivizumab for preventing respiratory syncytial virus in preterm neonates and infants in Colombia.

Cost-utility analysis of palivizumab for preventing respiratory syncytial virus in preterm neonates and infants in Colombia.

Fuente:Bmc Infectious Diseases

Extracto: Palivizumab is a cost-saving strategy in Colombia, effectively preventing RSV infection in preterm neonates and infants with BPD and CHD by reducing hospitalizations and lowering healthcare costs.

Claves:Bronchopulmonary dysplasia, Congenital heart defects, Palivizumab, Premature birth, Respiratory sounds, Respiratory syncytial viruses

Cita:BMC Infect Dis 2024 Apr 19; 24 (1) : 418.

Autor/es:Ordóñez, Jaime E (a)
Huertas, Victor M (b)

institución:(a) True Consulting, Medellín, Colombia. jaime.ordonez@trueconsulting.co.
(b) Fundación Cardioinfantil, Bogotá, Colombia.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1186/s12879-024-09300-5

E-learning-an interventional element of the PRiVENT project to improve weaning expertise.

E-learning-an interventional element of the PRiVENT project to improve weaning expertise.

Fuente:Bmc Medical Education

Tipo de trabajo:Revisión

Extracto: Especially for medical staff in intensive care units, where continuous training is often a challenge during shift work, e-learning is a useful supplement to existing medical training. TRIAL REGISTRATION: The PRiVENT study is registered at ClinicalTrials.gov (NCT05260853) on 02/03/2022.

Claves:E-learning, Knowledge transfer, Weaning from mechanical ventilation

Cita:BMC Med Educ 2024 Apr 19; 24 (1) : 420.

Autor/es:Michels-Zetsche, Julia D (a)
Schubert-Haack, Janina (b)

institución:(a) Department of Pneumology and Critical Care, Thoraxklinik, University Hosptial Heidelberg, Translational Lung Research Center Heidelberg (TLRC-H), Member of the German Center for Lung Research (DZL), Heidelberg, Germany. Julia.Michels@med.uni-heidelberg.de.
(b) aQua Institute for Applied Quality Improvement and Research in Health Care, Göttingen, Germany.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1186/s12909-024-05416-z

Pan-cancer analyses of immunogenic cell death-derived gene signatures: Potential biomarkers for prognosis and immunotherapy.

Fuente:Cancer Reports (hoboken, N.j.)

Extracto: We uncovered the potential of ICD gene signatures as comprehensive biomarkers for ICD in pan-cancer. Our research provides novel insights into immuno-phenotypic assessment and cancer therapeutic strategies, which could help to broaden the application of immunotherapy to benefit more patients.

Claves:immunogenic cell death, immunotherapy, pan‐cancer, prognosis, tumor microenvironment

Cita:Cancer Rep (Hoboken) 2024 Apr; 7 (4) : e2073.

Autor/es:Han, Xiaodan (a)
Song, Di (b)

institución:(a) Department of Radiation Oncology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
(b) Zhengzhou University, Zhengzhou, China.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe impreso

Idioma:Inglés

País de fuente:EE.UU.

Sitio web:http://dx.doi.org/10.1002/cnr2.2073

Possible germline mosaicism in a pedigree with Treacher Collins syndrome

Fuente:Science Progress

Tipo de trabajo:Revisión

Extracto: Our findings highlight the importance of considering germline mosaicism in sporadic de novo TCOF1 mutations when providing genetic consulting, and prenatal diagnosis is important when the proband's parents become pregnant again.

Claves:TCOF1, Treacher Collins syndrome, amniotic fluid puncture, case report, germline mosaicism

Cita:Sci Prog 2024 Apr-Jun; 107 (2) : 368504241242278.

Autor/es:Fan, Xinmiao (a)
Yang, Tengyu (b)

institución:(a) Department of Otolaryngology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China. RINGGOLD: 34732
(b) Department of Otolaryngology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China. RINGGOLD: 34732

Conflicto:Declaration of conflicting interestsThe authors declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.

Formato:Informe impreso

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1177/00368504241242278