Relationship between ocular manifestations, laboratory findings, echocardiographic findings, and intravenous immunoglobulin resistance in Kawasaki disease.

Fuente:Pediatric Rheumatology Online Journal

Extracto: Uveitis in KD is significantly associated with coronary artery dilatation, IVIG resistance, higher WBC count, platelet count, and CRP level.

Claves:Children, Kawasaki disease, Ocular involvements, Uveitis

Cita:Pediatr Rheumatol Online J 2024 May 1; 22 (1) : 50.

Autor/es:Jari, Mohsen (a)
Esmaeili, Hajar (b)

institución:(a) Department of Pediatric Rheumatology, Imam Hossein Children's Hospital, Isfahan University of Medical Sciences, Isfahan, Iran. mjari14@yahoo.com.
(b) School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.

Conflicto:The authors declare they have no competing interests.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1186/s12969-024-00985-1

A human pluripotent stem cell-derived in vitro model of the blood-brain barrier in cerebral malaria.

Fuente:Fluids and Barriers of The Cns

Extracto: These findings demonstrate the validity of our hiPSC-BMECs based model of the BBB, that displays enhanced barrier integrity and appropriate TJ protein localization. In the hiPSC-BMEC co-culture with Pf-iRBCs, reduced TEER, increased paracellular permeability, changes in TJ protein localization, increase in expression of adhesion molecules, and markers of angiogenesis and cellular stress all point towards a novel model with enhanced barrier properties, suitable for investigating pathogenic mechanisms underlying BBB disruption in CM.

Claves:Plasmodium falciparum-infected red blood cells, Blood–brain barrier, Cerebral malaria, Human induced pluripotent stem cell-derived brain microvascular endothelial cells

Cita:Fluids Barriers CNS 2024 May 1; 21 (1) : 38.

Autor/es:Gopinadhan, Adnan (a)
Hughes, Jason M (b)

institución:(a) Ryan White Center for Pediatric Infectious Disease and Global Health, Indiana University School of Medicine, R4-402D 1044 W. Walnut St., Indianapolis, IN, 46202, USA.
(b) Department of Microbiology and Immunology, Indiana University School of Medicine, Indianapolis, IN, 46202, USA.

Conflicto:The authors report no competing interests.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1186/s12987-024-00541-9

miR-133a and miR-135a Regulate All-Trans Retinoic Acid-Mediated Differentiation in Pediatric Acute Myeloid Leukemia by Inhibiting CDX2 Translation and Serve as Prognostic Biomarkers.

Fuente:Technology in Cancer Research & Treatment

Extracto: They hold promise as potentially favorable prognostic indicators and novel therapeutic targets for pediatric AML.

Claves:CDX2, acute myeloid leukemia, miR-133a, miR-135a, pediatric, prognosis

Cita:Technol Cancer Res Treat 2024 Jan-Dec; 23 : 15330338241248576.

Autor/es:Cheng, Yu-Cai (a)
Fan, Zhong (b)

institución:(a) Pediatric Hematology Laboratory, Division of Hematology/Oncology, Department of Pediatrics, The Seventh Affiliated Hospital of Sun Yat-Sen University, Shenzhen, Guangdong, China. RINGGOLD: 543160
(b) Department of Pediatrics, the First Affiliated Hospital, Sun Yat-Sen University, Guangzhou, China. RINGGOLD: 71068

Conflicto:Declaration of Conflicting InterestsThe authors declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.

Formato:Informe impreso

Idioma:Inglés

País de fuente:EE.UU.

Sitio web:http://dx.doi.org/10.1177/15330338241248576

Pädiatrische Rhinologie.

Fuente:Laryngo- Rhino- Otologie

Extracto: Furthermore, updates on the role of the ENT specialist in the care for children with cystic fibrosis and primary ciliary dyskinesia are provided.

Cita:Laryngorhinootologie 2024 May; 103 (S 01) : S188-S213.

Autor/es:Hackenberg, Stephan (a)
Renson, Ariane (b)

institución:(a) Klinik und Poliklinik für Hals-, Nasen- und Ohrenheilkunde, Kopf- und Halschirurgie, Universitätsklinikum Würzburg.
(b) Klinik für Hals-Nasen-Ohren-Heilkunde, Kopf- und Hals-Chirurgie, Uniklinik RWTH Aachen.

Conflicto:Die Autorinnen/Autoren geben an, dass kein Interessenkonflikt besteht.

Formato:Informe impreso

Idioma:eng, ger

País de fuente:Alemania

Sitio web:http://dx.doi.org/10.1055/a-2178-2957

Comparison of Whole Blood and Plasma for Monitoring Cytomegalovirus and Epstein-Barr Virus.

Fuente:The New Microbiologica

Extracto: These results indicate that whole blood is more sensitive for monitoring both EBV and CMV, whereas plasma is a potential alternative sample for monitoring CMV.

Claves:Epstein–Barr virus, cytomegalovirus, hematopoietic stem cell transplantation, real-time PCR, solid organ transplantation

Cita:New Microbiol 2024 May; 47 (1) : 52-59.

Autor/es:Fukuda, Yuto (a)
Torii, Yuka (b)

institución:(a) Department of Pediatrics, Nagoya University Graduate School of Medicine, 65 Tsurumai-cho, Showa-ku, Nagoya 466-8550, Japan.
(b) Department of Pediatrics, Nagoya University Graduate School of Medicine, 65 Tsurumai-cho, Showa-ku, Nagoya 466-8550, Japan.

Formato:Informe impreso

Idioma:Inglés

País de fuente:Italia

Sitio web:

KIJANI App to Promote Physical Activity in Children and Adolescents: Protocol for a Mixed Method Evaluation.

Fuente:Jmir Research Protocols

Tipo de trabajo:Estudio aleatorizado y controlado

Extracto: The study will help to determine the efficacy, applicability, and user experience of a gamified activity promotion application in children and adolescents. Overall, digital health approaches provide easy and wide reachability at low cost and are age appropriate and attractive for the target group of adolescents. Strategies have to be developed to apply digital health approaches in the best possible way for activity promotion. INTERNATIONAL REGISTERED REPORT IDENTIFIER (IRRID): DERR1-10.2196/55156.

Claves:KIJANI, KIJANI intervention, adolescence, adolescent, adolescents, augmented reality, childhood, children, digital health, gamification, health promotion, intervention, physical activity, user experience

Cita:JMIR Res Protoc 2024 May 3; 13 : e55156.

Autor/es:Willinger, Laura (a)
Böhm, Birgit (b)

institución:(a) Chair of Preventive Pediatrics, Technical University of Munich, Munich, Germany.
(b) Chair of Preventive Pediatrics, Technical University of Munich, Munich, Germany.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Canadá

Sitio web:http://dx.doi.org/10.2196/55156

Nitrogen dioxide exposure, health outcomes, and associated demographic disparities due to gas and propane combustion by U.S. stoves.

Fuente:Science Advances

Extracto: People living in residences <800 ft(2) in size incur four times more long-term NO(2) exposure than people in residences >3000 ft(2) in size; American Indian/Alaska Native and Black and Hispanic/Latino households incur 60 and 20% more NO(2) exposure, respectively, than the national average.

Cita:Sci Adv 2024 May 3; 10 (18) : eadm8680.

Autor/es:Kashtan, Yannai (a)
Nicholson, Metta (b)

institución:(a) Earth System Science Department, Stanford University, 473 Via Ortega, Stanford, CA 94305, USA.
(b) Earth System Science Department, Stanford University, 473 Via Ortega, Stanford, CA 94305, USA.

Formato:Informe impreso

Idioma:Inglés

País de fuente:EE.UU.

Sitio web:http://dx.doi.org/10.1126/sciadv.adm8680

Development of mobile CAT for patient feedback on pediatric consultations based on Rasch analysis of online techniques.

Fuente:Medicine

Extracto: The online tool holds promise as a valuable resource for researchers, students, and clinicians seeking accessible Rasch analysis solutions.

Cita:Medicine (Baltimore) 2024 May 3; 103 (18) : e37993.

Autor/es:Hsieh, Ju-Hao (a)
Chow, Julie Chi (b)

institución:(a) Department of Emergency Medicine, Chi Mei Medical Center, Tainan (700), Taiwan.
(b) Department of Pediatrics, Chi Mei Medical Center, Tainan, Taiwan.

Conflicto:The authors have no funding and conflicts of interest to disclose.

Formato:Informe impreso

Idioma:Inglés

País de fuente:EE.UU.

Sitio web:http://dx.doi.org/10.1097/MD.0000000000037993

Echocardiographic manifestations of mitochondrial disease with GTPBP3 gene mutations

Fuente:Medicine

Tipo de trabajo:Caso clínico

Extracto: LESSONS SUBSECTIONS: For echocardiographic indications of LV wall thickening and LV enlargement, one needs to be alert to the possibility of hereditary cardiomyopathy, especially in children.

Cita:Medicine (Baltimore) 2024 May 3; 103 (18) : e37847.

Autor/es:Tong, Qiaoli (a)
Miao, Yajing (b)

institución:Tong, Qiaoli (a)
Miao, Yajing (b)

Conflicto:The authors have no funding and conflicts of interest to disclose.

Formato:Informe impreso

Idioma:Inglés

País de fuente:EE.UU.

Sitio web:http://dx.doi.org/10.1097/MD.0000000000037847

Pediatric incarcerated inguinal hernia: Traditional open or laparoscopic-assisted approach?

Fuente:Medicine

Extracto: Its advantages include reduced trauma, faster recovery, shorter hospital stays, and fewer complications.

Cita:Medicine (Baltimore) 2024 May 3; 103 (18) : e37810.

Autor/es:Zhang, Guofeng (a)
Ding, Huanfei (b)

institución:(a) Department of Pediatric Surgery, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
(b) Department of Ultrasound, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe impreso

Idioma:Inglés

País de fuente:EE.UU.

Sitio web:http://dx.doi.org/10.1097/MD.0000000000037810

A novel flow cytometry panel to identify prognostic markers for steroid-sensitive forms of idiopathic nephrotic syndrome in childhood.

A novel flow cytometry panel to identify prognostic markers for steroid-sensitive forms of idiopathic nephrotic syndrome in childhood.

Fuente:Frontiers in Immunology

Tipo de trabajo:Estudio de cohortes

Extracto: We have set up a novel, reproducible, disease-specific flow cytometry panel that allows a comprehensive characterization of circulating lymphocytes. We found that, at disease onset, relapsing patients had significantly more transitional, CD19(+)CD27(+) memory and unswitched memory B cells and those who are at higher risk of relapse had increased circulating levels of unswitched memory B cells, independently of age. This approach can allow prediction of clinical evolution, monitoring of immunosuppression and tailored treatment in different forms of INS.

Claves:B cell, T cell, idiopathic nephrotic syndrome, lymphocyte profile, prognostic markers

Cita:Front Immunol 2024; 15 : 1379924.

Autor/es:Riganati, Martina (a)
Zotta, Federica (b)

institución:(a) Laboratory of Nephrology, Bambino Gesù Children's Hospital Scientific Institute for Research and Health Care (IRCCS), Rome, Italy.
(b) Division of Nephrology, Bambino Gesù Children's Hospital Scientific Institute for Research and Health Care (IRCCS), Rome, Italy.

Conflicto:The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3389/fimmu.2024.1379924

PyPop: a mature open-source software pipeline for population genomics.

Fuente:Frontiers in Immunology

Extracto: Code available at: https://zenodo.org/records/10080668 and https://github.com/alexlancaster/pypop.

Claves:HLA, MHC, bioinformatics, population genomics, software

Cita:Front Immunol 2024; 15 : 1378512.

Autor/es:Lancaster, Alexander K (a)
Single, Richard M (b)

institución:(a) Amber Biology LLC, Cambridge, MA, United States.
(b) Ronin Institute, Montclair, NJ, United States.

Conflicto:Authors AL and GW are co-owners of Amber Biology LLC. Author MM is the owner of Mariani Systems LLC. The remaining authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3389/fimmu.2024.1378512

When DNA-damage responses meet innate and adaptive immunity.

When DNA-damage responses meet innate and adaptive immunity.

Fuente:Cellular and Molecular Life Sciences Cmls

Extracto: The DDR network's immune modulators' dual roles may offer new perspectives on treating infectious disorders linked to DNA damage, including cancer, and on the development of target immunotherapy.

Claves:Adaptive immunity, DNA-damage response (DDR), IFN, Innate immunity, cGAS–STING

Cita:Cell Mol Life Sci 2024 Apr 17; 81 (1) : 185.

Autor/es:Tong, Jie (a)
Song, Jiangwei (b)

institución:(a) College of Life Science, Hebei University, Baoding, 071002, China.
(b) Institute of Life Science and Green Development, Hebei University, Baoding, 071002, China.

Conflicto:The authors claim no conflict of interest.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.1007/s00018-024-05214-2

Multicenter evaluation of complex urinary diversion for renal transplantation: outcomes of complex surgical solutions.

Multicenter evaluation of complex urinary diversion for renal transplantation: outcomes of complex surgical solutions.

Fuente:World Journal of Urology

Extracto: The mid-term kidney transplant function with complex urinary diversion appears to be comparable to transplants with regular urinary diversions. Hence, complex urinary diversion should always be considered as a surgical option, even during transplantation, if necessary.

Claves:Dialysis, Ileal conduit, Kidney transplantation, Renal insufficiency, Urinary diversion

Cita:World J Urol 2024 Apr 17; 42 (1) : 239.

Autor/es:Flegar, Luka (a)
Huber, Johannes (b)

institución:(a) Department of Urology, Philipps-University Marburg, Baldinger Street, 35043, Marburg, Germany. luka.flegar@uk-gm.de.
(b) Department of Urology, Philipps-University Marburg, Baldinger Street, 35043, Marburg, Germany.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Alemania

Sitio web:http://dx.doi.org/10.1007/s00345-024-04934-1

Knowledge, Attitudes, and Practices about Electronic Personal Health Records: A Cross-Sectional Study in a Region of Northern Italy.

Knowledge, Attitudes, and Practices about Electronic Personal Health Records: A Cross-Sectional Study in a Region of Northern Italy.

Fuente:Journal of Medical Systems

Extracto: Involving professionals in promoting this tool is crucial for helping patients and managing health data.

Claves:Electronic personal health records, Health data, Patient-centered care, Telemedicine, e-health

Cita:J Med Syst 2024 Apr 17; 48 (1) : 42.

Autor/es:Scaioli, Giacomo (a)
Martella, Manuela (b)

institución:(a) Department of Public Health Sciences and Paediatrics, University of Turin, Via Santena 5bis, Turin, 10126, Italy.
(b) Infection Control Unit, ASL TO3, Turin, Italy.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:EE.UU.

Sitio web:http://dx.doi.org/10.1007/s10916-024-02065-z

Comparing Open-Access Database and Traditional Intensive Care Studies Using Machine Learning: Bibliometric Analysis Study.

Comparing Open-Access Database and Traditional Intensive Care Studies Using Machine Learning: Bibliometric Analysis Study.

Fuente:Journal of Medical Internet Research

Tipo de trabajo:Revisión

Extracto: This study analyzed ICU research, providing valuable insights from a large number of publications. OAD studies complement TIC studies, focusing on predictive modeling, while TIC studies capture essential qualitative information. Integrating both approaches in a complementary manner is the future direction for ICU research. Additionally, natural language processing techniques offer a transformative alternative for literature review and bibliometric analysis.

Claves:BERTopic, MIMIC, Medical Information Mart for Intensive Care, critical care, eICU, machine learning, natural language processing

Cita:J Med Internet Res 2024 Apr 17; 26 : e48330.

Autor/es:Ke, Yuhe (a)
Yang, Rui (b)

institución:(a) Division of Anesthesiology and Perioperative Medicine, Singapore General Hospital, Singapore, Singapore.
(b) Centre for Quantitative Medicine, Duke-NUS Medical School, National University of Singapore, Singapore, Singapore.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Canadá

Sitio web:http://dx.doi.org/10.2196/48330

Screen time, social media use, and weight-related bullying victimization: Findings from an international sample of adolescents.

Screen time, social media use, and weight-related bullying victimization: Findings from an international sample of adolescents.

Fuente:Plos One

Extracto: Country-specific and global public health and technology efforts are needed to address this burgeoning social problem.

Cita:PLoS One 2024; 19 (4) : e0299830.

Autor/es:Ganson, Kyle T (a)
Pang, Nelson (b)

institución:(a) Factor-Inwentash Faculty of Social Work, University of Toronto, Toronto, Ontario, Canada.
(b) Factor-Inwentash Faculty of Social Work, University of Toronto, Toronto, Ontario, Canada.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:EE.UU.

Sitio web:http://dx.doi.org/10.1371/journal.pone.0299830

Family structure and the association with physical activity-Findings from 40 countries participating in the Health Behaviour in School-aged Children (HBSC) study.

Fuente:Plos One

Extracto: Family structure correlated with PA, but cross-country differences exist. The findings are relevant for the development of policies and programs to facilitate PA, especially in countries where living with one versus two parents was unfavourable. Additional country-specific research is needed to identify challenges for engaging in PA related to family structure.

Cita:PLoS One 2024; 19 (4) : e0300188.

Autor/es:Haug, Ellen (a)
Smith, Otto Robert Frans (b)

institución:(a) Department of Health Promotion and Development, University of Bergen, Bergen, Norway.
(b) Department of Teacher Education, NLA University College, Bergen, Norway.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:EE.UU.

Sitio web:http://dx.doi.org/10.1371/journal.pone.0300188

Impact of COVID-19 on acute appendicitis presentation, management and pathology findings in adult and paediatric populations.

Fuente:Plos One

Tipo de trabajo:Revisión

Extracto: Year 1 of the COVID-19 pandemic was associated with delayed presentation of acute appendicitis in adults and children. In adults, an overall reduction in appendicectomy operations, increased use of pre-operative diagnostic imaging, and fewer specimens showing simple acute appendicitis or non-diagnostic features, collectively support appropriate restriction of surgery for those patients with a more certain acute appendicitis diagnosis.

Cita:PLoS One 2024; 19 (4) : e0300357.

Autor/es:Johnston, Dorothy B (a)
Coleman, Helen G (b)

institución:(a) Centre for Public Health, Queen's University Belfast, Belfast, United Kingdom.
(b) Centre for Public Health, Queen's University Belfast, Belfast, United Kingdom.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:EE.UU.

Sitio web:http://dx.doi.org/10.1371/journal.pone.0300357

Outcomes after cancer diagnosis in children and adult patients with congenital heart disease in Sweden

Outcomes after cancer diagnosis in children and adult patients with congenital heart disease in Sweden

Fuente:Bmj Open

Tipo de trabajo:Estudio de cohortes

Extracto: Cancer-related deaths constituted 1.8% of all mortalities across all CHD patients. Among CHD patients with cancer, 18.3% died, with cancer being the cause in 71.9% of cases. Although CHD patients have an increased cancer risk, their mortality risk post-diagnosis does not significantly differ from non-CHD patients after adjustements and exclusion of patients with genetic syndromes and transplant recipients. However, CHD patients with genetic syndromes and concurrent cancer appear to be a vulnerable group.

Claves:CARDIOLOGY, Congenital heart disease, Epidemiology, ONCOLOGY, Prognosis

Cita:BMJ Open 2024 Apr 17; 14 (4) : e083237.

Autor/es:Karazisi, Christina (a)
Dellborg, Mikael (b)

institución:(a) Department of Molecular and Clinical Medicine, University of Gothenburg, Goteborg, Sweden christina.karazisi@vgregion.se.
(b) Department of Medicine, Geriatrics and Emergency Medicine, Region Västra Götaland, Sahlgrenska University Hospital, Goteborg, Sweden.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1136/bmjopen-2023-083237