Prescription drug monitoring programs and prescription pain medication misuse among U.S. high school students-2019.

Prescription drug monitoring programs and prescription pain medication misuse among U.S. high school students-2019.

Fuente:Bmc Public Health

Extracto: None of the five PDMP dimensions were associated with lower prescription pain medication misuse, however further research is needed, especially as new YRBS data become available.

Claves:Prescription drug monitoring programs, Prescription pain medication misuse, Youth risk behavior survey

Cita:BMC Public Health 2024 May 10; 24 (1) : 1276.

Autor/es:Liu, Kevin (a)
Benedetti, Marco (b)

institución:(a) Center for Injury Research and Policy, Abigail Wexner Research Institute at Nationwide Children's Hospital, Columbus, OH, USA.
(b) Center for Injury Research and Policy, Abigail Wexner Research Institute at Nationwide Children's Hospital, Columbus, OH, USA.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1186/s12889-024-18698-1

Serum stromal cell-derived factor-1 concentrations are increased and associated with nonalcoholic fatty liver disease in children with obesity.

Serum stromal cell-derived factor-1 concentrations are increased and associated with nonalcoholic fatty liver disease in children with obesity.

Fuente:Bmc Endocrine Disorders

Extracto: These results suggest that SDF-1 levels are elevated in obese children and are associated with NAFLD, indicating that SDF-1 may play a role in the development of childhood obesity and metabolic disorders.

Claves:Childhood obesity, Nonalcoholic fatty liver disease, SDF-1

Cita:BMC Endocr Disord 2024 May 10; 24 (1) : 67.

Autor/es:Liu, Yuesheng (a)
Hao, Lijun (b)

institución:(a) Department of Pediatrics, The Second Affiliated Hospital of Xi an Jiaotong University, Xiwu Road, Xi ', Shaanxi, 710000, People's Republic of China.
(b) Neonatal Department, Xi'an People's Hospital (Xi'an Fourth Hospital), Xi'an, China.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1186/s12902-024-01597-2

Comparison of dmft and behavior rating scores between children with systemic disease and healthy children at the first dental visit.

Comparison of dmft and behavior rating scores between children with systemic disease and healthy children at the first dental visit.

Fuente:Bmc Oral Health

Extracto: The presence of chronic disease in children appeared to affect the cooperation negatively at the first dental visit compared to healthy controls, however, it did not affect the oral health negatively. Having a negative behavior score or SD did not necessitate the use of GA/S for dental treatment.

Claves:Children, Chronic disease, Cooperation, Oral health

Cita:BMC Oral Health 2024 May 10; 24 (1) : 548.

Autor/es:Erbas Unverdi, Gizem (a)
Ozgur, Beste (b)

institución:(a) Department of Pediatric Dentistry, Faculty of Dentistry, Hacettepe University, 06100, Sihhiye, Ankara, Turkey. erbasgizem@gmail.com.
(b) Department of Pediatric Dentistry, Faculty of Dentistry, Hacettepe University, 06100, Sihhiye, Ankara, Turkey.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1186/s12903-024-04285-8

Left knee septic monoarthritis in a pediatric patient due to shewanella putrefaciens

Left knee septic monoarthritis in a pediatric patient due to shewanella putrefaciens

Fuente:Annals of Clinical Microbiology and Antimicrobials

Tipo de trabajo:Revisión

Extracto: This case highlights the bacteriological and clinical characteristics, as well as the antibiogram, of Shewanella spp. Given the recent increase in notifications of Shewanella infections, predominantly by S. algae and S. putrefaciens, it is essential to consider these pathogens in patients with a history of contact with bodies of water. Special attention must be paid to their resistance patterns in patient management to prevent the development of intrinsic antimicrobial resistance.

Claves:Shewanella putrefaciens, Colombia, Pediatrics, Penetrating wound, Septic arthritis

Cita:Ann Clin Microbiol Antimicrob 2024 May 10; 23 (1) : 43.

Autor/es:Madrid, Nathalie Yepes (a)
Mejia, Luis Fernando (b)

institución:(a) Pediatric specialty resident, Universidad Libre Sectional Cali, Valle del Cauca, Colombia. nathalieyepesmadrid@yahoo.com.
(b) Pediatrics Specialty Research Group (GRINPED), Valle del Cauca, Colombia. nathalieyepesmadrid@yahoo.com.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1186/s12941-024-00702-6

Short developmental milestone risk assessment tool to identify Duchenne muscular dystrophy in primary care.

Short developmental milestone risk assessment tool to identify Duchenne muscular dystrophy in primary care.

Fuente:Orphanet Journal of Rare Diseases

Tipo de trabajo:Estudio clínico

Extracto: The majority of boys (79%) with DMD can be identified between 12 and 36 months of age with this tool. It increases the initial a priori risk of DMD from 1 in 5,000 to approximately 1 in 268 boys. We expect that other neuromuscular disorders and disabilities can also be found with this tool.

Claves:Child Development, Developmental Delay, Early Childhood Development, Motor skills, Pediatrics; neuromuscular disorder

Cita:Orphanet J Rare Dis 2024 May 10; 19 (1) : 192.

Autor/es:van Dommelen, Paula (a)
van Dijk, Oisín (b)

institución:(a) Department of Child Health, The Netherlands Organization for Applied Scientific Research TNO, Leiden, The Netherlands. Paula.vanDommelen@tno.nl.
(b) Department of Public Health and Primary Care, Leiden University Medical Center, Leiden, The Netherlands.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1186/s13023-024-03208-8

(2,6-Dimethylphenyl)arsonic Acid Induces Apoptosis through the Mitochondrial Pathway, Downregulates XIAP, and Overcomes Multidrug Resistance to Cytostatic Drugs in Leukemia and Lymphoma Cells In Vitro.

(2,6-Dimethylphenyl)arsonic Acid Induces Apoptosis through the Mitochondrial Pathway, Downregulates XIAP, and Overcomes Multidrug Resistance to Cytostatic Drugs in Leukemia and Lymphoma Cells In Vitro.

Fuente:International Journal of Molecular Sciences

Extracto: Due to the selective apoptosis induction, the synergistic effects with common anti-cancer drugs, and the ability to overcome multidrug resistance in vitro, As2 represents a promising candidate for further preclinical investigations with respect to refractory malignancies.

Claves:XIAP (x-linked inhibitor of apoptosis protein), apoptosis, arsenic, cancer chemotherapy, leukemia, lymphoma, mitochondrial pathway, multidrug resistance, synergy

Cita:Int J Mol Sci 2024 Apr 26; 25 (9)

Autor/es:Wilke, Nathalie (a)
Frias, Corazon (b)

institución:(a) Department of Pediatric Hematology/Oncology, Children's Hospital Cologne, Amsterdamer Straße 59, 50735 Cologne, Germany.
(b) Department of Pediatric Hematology/Oncology, Children's Hospital Cologne, Amsterdamer Straße 59, 50735 Cologne, Germany.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3390/ijms25094713

Exosomes Secreted by Wharton's Jelly-Derived Mesenchymal Stem Cells Promote the Ability of Cell Proliferation and Migration for Keratinocyte.

Fuente:International Journal of Molecular Sciences

Extracto: Exploring the various components of AD-MSC and WJ-MSC exosomes can aid in their different clinical applications.

Claves:Wharton’s jelly mesenchymal stem cell, adipose tissue mesenchymal stem cell, exosome, fibrinogen beta chain, iTRAQ

Cita:Int J Mol Sci 2024 Apr 26; 25 (9)

Autor/es:Yu, Hong-Ren (a)
Huang, Hsin-Chun (b)

institución:(a) Department of Pediatrics, Kaohsiung Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Kaohsiung 833401, Taiwan.
(b) Department of Pediatrics, Kaohsiung Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Kaohsiung 833401, Taiwan.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3390/ijms25094758

Host RNA Expression Signatures in Young Infants with Urinary Tract Infection: A Prospective Study.

Fuente:International Journal of Molecular Sciences

Extracto: Our results indicate a need for further investigation and consideration of UTI in young infants before implementing host RNA expression signatures in clinical practice.

Claves:host RNA expression signatures, transcriptomics, urinary tract infection, young infants

Cita:Int J Mol Sci 2024 Apr 29; 25 (9)

Autor/es:Dungu, Kia Hee Schultz (a)
Carlsen, Emma Louise Malchau (b)

institución:(a) Department of Pediatrics & Adolescent Medicine, Copenhagen University Hospital, Rigshospitalet, 2100 Copenhagen, Denmark.
(b) Department of Clinical Medicine, University of Copenhagen, 2200 Copenhagen, Denmark.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3390/ijms25094857

The Evolving Landscape of Flowcytometric Minimal Residual Disease Monitoring in B-Cell Precursor Acute Lymphoblastic Leukemia.

Fuente:International Journal of Molecular Sciences

Extracto: Future directions involve integrating artificial intelligence, further automation, and exploring multicolor spectral flow cytometry to standardize MRD assessment and enhance diagnostic and prognostic robustness of MRD diagnostics in BCP-ALL.

Claves:B-cell precursor acute lymphoblastic leukemia, automated analysis, flow cytometry, immunotherapy, machine learning, minimal residual disease, next-generation flow cytometry

Cita:Int J Mol Sci 2024 Apr 30; 25 (9)

Autor/es:Verbeek, Martijn W C (a)
van der Velden, Vincent H J (b)

institución:(a) Laboratory for Medical Immunology, Department of Immunology, Erasmus MC, University Medical Center Rotterdam, 3015 GD Rotterdam, The Netherlands.
(b) Laboratory for Medical Immunology, Department of Immunology, Erasmus MC, University Medical Center Rotterdam, 3015 GD Rotterdam, The Netherlands.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3390/ijms25094881

A Randomized Controlled Cluster Trial of an Obesity Prevention Program for Children with Special Health Care Needs: Methods and Implications.

A Randomized Controlled Cluster Trial of an Obesity Prevention Program for Children with Special Health Care Needs: Methods and Implications.

Fuente:Nutrients

Extracto: CCCs are an ideal setting for targeting CSHCN for obesity prevention efforts as they provide an opportunity to address modifiable risk factors.

Claves:children, early childhood, obesity, prevention, special health care needs

Cita:Nutrients 2024 Apr 25; 16 (9)

Autor/es:Natale, Ruby (a)
Schladant, Michelle (b)

institución:(a) Mailman Center for Child Development, Department of Pediatrics, University of Miami School of Medicine, Miami, FL 33136, USA.
(b) Mailman Center for Child Development, Department of Pediatrics, University of Miami School of Medicine, Miami, FL 33136, USA.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3390/nu16091274

The Benefits of the Mediterranean Diet on Inflamm-Aging in Childhood Obesity.

Fuente:Nutrients

Tipo de trabajo:Revisión

Extracto: Future high-quality intervention studies are necessary to elucidate the specific impact of the MD on inflammation in diverse pediatric populations with obesity and associated comorbidities.

Claves:Mediterranean diet, childhood obesity, children, inflamm-aging, nutrition, pediatric

Cita:Nutrients 2024 Apr 25; 16 (9)

Autor/es:Calcaterra, Valeria (a)
Verduci, Elvira (b)

institución:(a) Pediatrics and Adolescentology Unit, Department of Internal Medicine, University of Pavia, 27100 Pavia, Italy.
(b) Pediatric Department, Buzzi Children's Hospital, 20154 Milan, Italy.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3390/nu16091286

Impact of Serious Games on Body Composition, Physical Activity, and Dietary Change in Children and Adolescents

Fuente:Nutrients

Tipo de trabajo:Revisión sistemática

Extracto: Serious games show potential as tools for overweight/obesity control among children and adolescents but may require longer intervention to sustain its effect.

Claves:adolescents, body composition, children, dietary change, physical activity, serious game

Cita:Nutrients 2024 Apr 26; 16 (9)

Autor/es:Liu, Mingchang (a)
Guan, Xinyue (b)

institución:(a) Institute for Hospital Management, School of Medicine, Tsinghua University, Beijing 100084, China.
(b) Institute for Hospital Management, School of Medicine, Tsinghua University, Beijing 100084, China.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3390/nu16091290

Resin infiltration versus fluoride varnish for visual improvement of white spot lesions during multibracket treatment. A randomized-controlled clinical trial.

Resin infiltration versus fluoride varnish for visual improvement of white spot lesions during multibracket treatment. A randomized-controlled clinical trial.

Fuente:Clinical Oral Investigations

Extracto: WSL infiltration management during orthodontic treatment was superior to topical fluoridation in not only arresting the enamel lesions but also significantly improving the aesthetic appearance of demineralized regions around the brackets. CLINICAL RELEVANCE: WSL treatment in orthodontic patients is usually initiated after debonding. Research has shown that the earlier WSL is treated, the better the aesthetic outcome. There is limited data on the efficacy of resin infiltration of WSL during orthodontic treatment.

Claves:Demineralization, Fluoride, Multibracket appliance, Orthodontics, Resin infiltration, White spot lesions

Cita:Clin Oral Investig 2024 May 11; 28 (6) : 308.

Autor/es:Kashash, Yamen (a)
Hein, Sascha (b)

institución:(a) Depatment of Orthodontics and Dentofacial Orthopedics, Charité - Universitätsmedizin Berlin, Aßmannshauser Straße 4-6, 14197, Berlin, Germany.
(b) School of Design, University of Leeds, Woodhouse Lane, Leeds, LS2 9JT, England.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Alemania

Sitio web:http://dx.doi.org/10.1007/s00784-024-05695-2

Impact of inadequate empirical antibiotic treatment on outcome of non-critically ill children with bacterial infections.

Impact of inadequate empirical antibiotic treatment on outcome of non-critically ill children with bacterial infections.

Fuente:Bmc Pediatrics

Tipo de trabajo:Revisión

Extracto: inadequate antibiotic treatment did not affect the outcomes of non-critically ill children with bacterial infectious diseases. Therefore, routine empirical broad-spectrum treatment may not be necessary for these cases, as it can lead to additional costs and contribute to antibiotic resistance. Larger prospective studies are needed to confirm these findings.

Claves:Bacteremia, Children, Inadequate antibiotic treatment, Renal abnormalities, Risk factors

Cita:BMC Pediatr 2024 May 11; 24 (1) : 324.

Autor/es:Dar, Amit (a)
Abram, Tali Bdolah (b)

institución:(a) Department of Internal Medicine, Hadassah-Hebrew University Medical Center, Ein Kerem, Jerusalem, Israel.
(b) Faculty of Medicine, Hebrew University of Jerusalem, Jerusalem, Israel.

Conflicto:The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1186/s12887-024-04793-0

Exploratory factor analysis yields grouping of brain injury biomarkers significantly associated with outcomes in neonatal and pediatric ECMO.

Exploratory factor analysis yields grouping of brain injury biomarkers significantly associated with outcomes in neonatal and pediatric ECMO.

Fuente:Scientific Reports

Extracto: Application of EFA on plasma brain injury biomarkers in children on ECMO yielded grouping of biomarkers into three factors that were significantly associated with unfavorable outcome, suggesting future potential as prognostic instruments.

Claves:Biomarkers, Brain injury, Child, Extracorporeal membrane oxygenation, Neurologic outcome

Cita:Sci Rep 2024 May 11; 14 (1) : 10790.

Autor/es:Huang, Victoria (a)
Roem, Jennifer (b)

institución:(a) Department of Anesthesiology and Critical Care Medicine, Johns Hopkins University School of Medicine, 1800 Orleans Street, Bloomberg Suite 6321, Baltimore, MD, 21287, USA.
(b) Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1038/s41598-024-61388-6

Predicting early mortality and severe intraventricular hemorrhage in very-low birth weight preterm infants: a nationwide, multicenter study using machine learning.

Fuente:Scientific Reports

Extracto: We developed a robust machine learning-based outcome predictor using only four accessible variables, offering valuable prognostic information for parents and aiding healthcare providers in decision-making.

Cita:Sci Rep 2024 May 12; 14 (1) : 10833.

Autor/es:Yang, Yun-Hsiang (a)
Wang, Ts-Ting (b)

institución:(a) Department of Pediatrics, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, No.138, Sheng Li Road, Tainan, Taiwan.
(b) Department of Pediatrics, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, No.138, Sheng Li Road, Tainan, Taiwan.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1038/s41598-024-61749-1

Simultaneous detection of dental caries and fissure sealant in intraoral photos by deep learning: a pilot study.

Simultaneous detection of dental caries and fissure sealant in intraoral photos by deep learning: a pilot study.

Fuente:Bmc Oral Health

Extracto: The proposed deep learning model achieved multi-task simultaneous detection in intraoral photos and showed good performance in the detection of dental caries and fissure sealants. Compared with 1-year dentist, the model has advantages in caries detection and is equivalent in fissure sealants detection.

Claves:Artificial intelligence, Deep learning, Dental caries, Fissure sealant

Cita:BMC Oral Health 2024 May 12; 24 (1) : 553.

Autor/es:Xiong, Yanshan (a)
Zhang, Hongyuan (b)

institución:(a) Department of Endodontics, Shenzhen Stomatology Hospital, Shenzhen, Guangdong, China.
(b) Medical AI Lab, School of Biomedical Engineering, Medical School, Shenzhen University, Shenzhen, Guangdong, China.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1186/s12903-024-04254-1

The knowledge regarding the impacts and management of black triangles among dental professionals and laypeople.

The knowledge regarding the impacts and management of black triangles among dental professionals and laypeople.

Fuente:Scientific Reports

Extracto: Age and gender had no relationships with the knowledge of causes or management of BT.

Claves:Appearance, Black triangles, Gingival embrasure, Interdental papillae, Knowledge, Satisfaction, Smile

Cita:Sci Rep 2024 May 12; 14 (1) : 10840.

Autor/es:Al-Omiri, Mahmoud K (a)
Atieh, Danial Waleed Ahmad (b)

institución:(a) Department of Fixed and Removable Prosthodontics, School of Dentistry, The University of Jordan, Queen Rania Street, Amman, 11942, Jordan. alomirim@yahoo.co.uk.
(b) Department of Prosthodontics, The City of London Dental School, Canada Water, Lower Road, London, UK. alomirim@yahoo.co.uk.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1038/s41598-024-61356-0

Transition to a mesenchymal state in neuroblastoma may be characterized by a high expression of GD2 and by the acquisition of immune escape from NK cells.

Transition to a mesenchymal state in neuroblastoma may be characterized by a high expression of GD2 and by the acquisition of immune escape from NK cells.

Fuente:Frontiers in Immunology

Extracto: NB is a heterogeneous tumor representing a further hurdle in NB immunotherapy. However, different from what was reported with NB commercial cells and independent of their MES/ADRN phenotype, the expression of GD2 and its displayed sensitivity to anti-GD2 mAb ADCC indicated the possible effectiveness of anti-GD2 immunotherapy.

Claves:NK cells, ganglioside sialic acid-containing glycosphingolipid-2, immunotherapy, neuroblastoma, primary tumor cells

Cita:Front Immunol 2024; 15 : 1382931.

Autor/es:Di Matteo, Sabina (a)
Bilotta, Maria Teresa (b)

institución:(a) Tumour Immunology Unit, Bambino Gesù Children's Hospital Istituto di Ricerca e Cura a Carattere Scientifico (IRCCS), Rome, Italy.
(b) Innate Lymphoid Cells Unit, Immunology Research Area, Bambino Gesù Children's Hospital Istituto di Ricerca e Cura a Carattere Scientifico (IRCCS), Rome, Italy.

Conflicto:The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. The author(s) declared that they were an editorial board member of Frontiers, at the time of submission. This had no impact on the peer review process and the final decision.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3389/fimmu.2024.1382931

Parental perception of nocturnal enuresis in a local region of Saudi Arabia.

Parental perception of nocturnal enuresis in a local region of Saudi Arabia.

Fuente:Journal of Medicine and Life

Extracto: The level of education and the number of children were predictors of knowledge and a positive attitude toward NE in children.

Claves:children, nocturnal enuresis, perceptions

Cita:J Med Life 2024 Jan; 17 (1) : 73-80.

Autor/es:Alarfaj, Haytham Mohammed (a)
Almaqhawi, Abdullah (b)

institución:(a) Department of Surgery, College of Medicine, King Faisal University, Al Hofuf, Saudi Arabia.
(b) Department of Family and Community Medicine, College of Medicine, King Faisal University, Al Hofuf, Saudi Arabia.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe impreso

Idioma:Inglés

País de fuente:Rumania

Sitio web:http://dx.doi.org/10.25122/jml-2023-0423