An algorithm to identify patients aged 0-3 with rare genetic disorders.

An algorithm to identify patients aged 0-3 with rare genetic disorders.

Fuente:Orphanet Journal of Rare Diseases

Tipo de trabajo:Revisión

Extracto: The PheIndex algorithm can help identify when a rare genetic disorder may be present, alerting providers to consider ordering a diagnostic genetic test and/or referring a patient to a medical geneticist.

Claves:Algorithm, Clinical decision-making, Digital phenotyping, Pediatric genetic disorders

Cita:Orphanet J Rare Dis 2024 May 2; 19 (1) : 183.

Autor/es:Webb, Bryn D (a)
Lau, Lisa Y (b)

institución:(a) Department of Pediatrics, University of Wisconsin School of Medicine and Public Health, Madison, WI, USA. bdwebb@wisc.edu.
(b) GeneDx Holdings Corp, (formerly known as Sema4 Holdings Corp.), Stamford, Connecticut, CT, USA. bdwebb@wisc.edu.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1186/s13023-024-03188-9

Comparison between XGboost model and logistic regression model for predicting sepsis after extremely severe burns.

Comparison between XGboost model and logistic regression model for predicting sepsis after extremely severe burns.

Fuente:The Journal of International Medical Research

Extracto: The XGboost model was superior to the LR model in predictive efficacy. Results suggest that, fibrinogen, NLR, BI, and age were correlated with sepsis after extremely severe burns.

Claves:Extremely Severe Burn, Logistic Regression, Risk Factors, Sepsis, XGboost

Cita:J Int Med Res 2024 May; 52 (5) : 3000605241247696.

Autor/es:Liu, Peng (a)
Li, Xiao-Jian (b)

institución:(a) Department of Burn and Plastic, Guangzhou Red Cross Hospital, Medical College, Jinan University, Guangzhou, China. RINGGOLD: 74714
(b) Department of Burn and Plastic, Guangzhou Red Cross Hospital, Medical College, Jinan University, Guangzhou, China. RINGGOLD: 74714

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe impreso

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1177/03000605241247696

Case report: Development of central precocious puberty in a girl with late-diagnosed simple virilizing congenital adrenal hyperplasia complicated with Williams syndrome.

Case report: Development of central precocious puberty in a girl with late-diagnosed simple virilizing congenital adrenal hyperplasia complicated with Williams syndrome.

Fuente:Frontiers in Endocrinology

Extracto: This case report delves into the pubertal change patterns in a patient affected by overlapping genetic conditions, providing valuable insights in to the intricate clinical manifestation and management of these rare complex disorders.

Claves:Williams syndrome, case report, central precocious puberty, congenital adrenal hyperplasia, late diagnosis, simple virilizing type

Cita:Front Endocrinol (Lausanne) 2024; 15 : 1352552.

Autor/es:Joo, Eun Young (a)
Yoo, Myung Ji (b)

institución:(a) Department of Pediatrics, Inha University College of Medicine, Inha University Hospital, Incheon, Republic of Korea.
(b) Department of Pediatrics, Inha University College of Medicine, Inha University Hospital, Incheon, Republic of Korea.

Conflicto:The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3389/fendo.2024.1352552

Aesthetic perception of patient in developmental age in interceptive orthodontic treatment.

Aesthetic perception of patient in developmental age in interceptive orthodontic treatment.

Fuente:European Journal of Paediatric Dentistry

Extracto: Interceptive orthodontic treatment has proven to be of valid clinical and psychological help. This result is confirmed by the complete aesthetic satisfaction of the patient in the frontal and latero-lateral planes.

Cita:Eur J Paediatr Dent 2024 Apr 1; 25 : 1.

Autor/es:Parisi, G (a)
Partipilo, E (b)

institución:(a) DDS, Post graduate School of Paediatric Dentistry University of Rome "Tor Vergata", Rome, Italy.
(b) DDS, Post graduate School of Paediatric Dentistry University of Rome "Tor Vergata", Rome, Italy.

Formato:Informe impreso

Idioma:Inglés

País de fuente:Italia

Sitio web:http://dx.doi.org/10.23804/ejpd.2024.25.02.02

Examining Antimicrobial Stewardship Program Implementation in Carceral Settings.

Examining Antimicrobial Stewardship Program Implementation in Carceral Settings.

Fuente:Ama Journal of Ethics

Extracto: This article draws on a case of dental infection suffered by a woman who is incarcerated to consider key ethical and clinical complexities of antimicrobial prescribing in carceral settings.

Cita:AMA J Ethics 2024 May 1; 26 (5) : E399-407.

Autor/es:Wurcel, Alysse Gail (a)
Abdul-Mutakabbir, Jacinda C (b)

institución:(a) Infectious diseases clinician at Tufts Medical Center in Boston, Massachusetts.
(b) Assistant professor of clinical pharmacy in the Division of Clinical Pharmacy at the Skaggs School of Pharmacy and Pharmaceutical Sciences at the University of California, San Diego.

Formato:Informe virtual

Idioma:Inglés

País de fuente:EE.UU.

Sitio web:http://dx.doi.org/10.1001/amajethics.2024.399

Investigation of the fungiform papillae number in children with tooth number anomalies.

Investigation of the fungiform papillae number in children with tooth number anomalies.

Fuente:Clinical Oral Investigations

Extracto: The lower FP numbers in children with hypodontia suggested an association between teeth and FP number. However, the non-significant difference in FP numbers with hyperdontia underscored the complexity of tooth development, warranting further investigations. CLINICAL RELEVANCE: Children with hypodontia may exhibit distinct FP numbers compared to those without tooth number anomalies.

Claves:Fungiform papillae, Hyperdontia, Hypodontia, Tooth number anomaly

Cita:Clin Oral Investig 2024 May 3; 28 (5) : 297.

Autor/es:Alp, Belgin (a)
Kalaoglu, Elif Ece (b)

institución:(a) Trabzon Dental Public Health Hospital, Trabzon, Turkey.
(b) Department of Pediatric Dentistry, Faculty of Dentistry, İstanbul Gelişim University, Istanbul, Turkey. elifece.sar@gmail.com.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Alemania

Sitio web:http://dx.doi.org/10.1007/s00784-024-05696-1

Germline findings in cancer predisposing genes from a small cohort of chordoma patients.

Germline findings in cancer predisposing genes from a small cohort of chordoma patients.

Fuente:Journal of Cancer Research and Clinical Oncology

Extracto: We report here a chordoma cohort of 24 families with newly found germline genetic mutations in cancer predisposing genes. We discuss implications for genetic counseling, clinical management, and universal germline genetic testing for cancer patients with solid tumors.

Claves:Chordoma, Genetic counseling, Germline, Hereditary, Predisposition

Cita:J Cancer Res Clin Oncol 2024 May 3; 150 (5) : 227.

Autor/es:Raygada, Margarita (a)
John, Liny (b)

institución:(a) Pediatric Oncology Branch, Center for Cancer Research, National Cancer Institute, Bethesda, MD, USA. Raygadam@mail.nih.gov.
(b) NIH Clinical Center (Building 10), 10 Center Drive, Room 1-3750, Bethesda, MD, 20892, USA. Raygadam@mail.nih.gov.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Alemania

Sitio web:http://dx.doi.org/10.1007/s00432-024-05706-5

Real-Time Electronic Patient Portal Use Among Emergency Department Patients.

Real-Time Electronic Patient Portal Use Among Emergency Department Patients.

Fuente:Jama Network Open

Extracto: AND RELEVANCE: These findings suggest that real-time patient portal use during ED encounters has increased over time, but disparities exist in portal access that mirror trends in portal usage more generally. Given emergency medicine's role in caring for medically underserved patients, there are opportunities for EDs to enroll and train patients in using patient portals to promote engagement during and after their visits.

Cita:JAMA Netw Open 2024 May 1; 7 (5) : e249831.

Autor/es:Turer, Robert W (a)
McDonald, Samuel A (b)

institución:(a) Department of Emergency Medicine, University of Texas Southwestern Medical Center, Dallas.
(b) Clinical Informatics Center, University of Texas Southwestern Medical Center, Dallas.

Conflicto:Conflict of Interest Disclosures: Dr Lehmann reported receiving an honorarium from Springer for a textbook outside this submitted work. Dr Steitz reported receiving grants from the National Institute on Aging during the conduct of the study. No other disclosures were reported.

Formato:Informe virtual

Idioma:Inglés

País de fuente:EE.UU.

Sitio web:http://dx.doi.org/10.1001/jamanetworkopen.2024.9831

Timing of Red Blood Cell Transfusions and Occurrence of Necrotizing Enterocolitis

Fuente:Jama Network Open

Tipo de trabajo:Estudio clínico aleatorizado

Extracto: AND RELEVANCE: The findings of this post hoc analysis suggest that, among ELBW infants with the hemoglobin ranges occurring in the TOP trial, exposure to RBC transfusions was not temporally associated with a higher risk of NEC during 72-hour posttransfusion hazard periods. Given that the incidence rate of NEC peaked between postnatal days 20 and 29 among infants with lower hemoglobin values, a more in-depth examination of this at-risk period using larger data sets is warranted. TRIAL REGISTRATION: ClinicalTrials.gov Identifier: NCT01702805.

Cita:JAMA Netw Open 2024 May 1; 7 (5) : e249643.

Autor/es:Salas, Ariel A (a)
Gunn, Elizabeth (b)

institución:(a) Department of Pediatrics, University of Alabama at Birmingham.
(b) Department of Pediatrics, University of Alabama at Birmingham.

Conflicto:Conflict of Interest Disclosures: Dr Salas reported receiving grants and personal fees from Reckitt/Mead Johnson and stock options from Resbiotic outside the submitted work; in addition, Dr Salas had a patent for an instrumented feeding bottle issued to the University of Alabama. Dr Josephson reported receivng personal fees from Westat and grants from Medtronics outside the submitted work. Dr Kirpalani... reported being principal investigator of the Transfusion of Prematures (TOP) study. No other disclosures were reported.

Formato:Informe virtual

Idioma:Inglés

País de fuente:EE.UU.

Sitio web:http://dx.doi.org/10.1001/jamanetworkopen.2024.9643

Impacts on paediatricians testifying in cases of child maltreatment

Impacts on paediatricians testifying in cases of child maltreatment

Fuente:Bmj Open

Tipo de trabajo:Revisión sistemática

Extracto: An article reporting the results of the systematic review will be submitted for publication in a scientific journal, presented at relevant conferences and used in subsequent stakeholder consultations.

Claves:Child protection, Non-accidental injury, PAEDIATRICS

Cita:BMJ Open 2024 May 3; 14 (5) : e081331.

Autor/es:Horstman, Alyce (a)
Smith, J Anne S (b)

institución:(a) Department of Forensic Medicine, Monash University, Southbank, Victoria, Australia alyce.horstman@rch.org.au.
(b) Victorian Forensic Paediatric Medical Service, The Royal Children's Hospital Melbourne, Melbourne, Victoria, Australia.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1136/bmjopen-2023-081331

Influencing risk factors of voriconazole-induced liver injury in Uygur pediatric patients undergoing allogeneic hematopoietic stem cell transplantation.

Influencing risk factors of voriconazole-induced liver injury in Uygur pediatric patients undergoing allogeneic hematopoietic stem cell transplantation.

Fuente:Bmc Pediatrics

Extracto: There was a significant correlation between voriconazole-induced liver injury and voriconazole trough concentration in high-risk Uygur pediatric patients with allogeneic HSCT.

Claves:CYP2C19, UGT1A4, HSCT, Liver injury, Voriconazole

Cita:BMC Pediatr 2024 May 3; 24 (1) : 299.

Autor/es:Zhao, Ting (a)
Zhang, Hui-Lan (b)

institución:(a) Department of Pharmacy, People's Hospital of Xinjiang Uygur Autonomous Region, Urumqi, 830001, Xinjiang, China.
(b) Institute of Clinical Pharmacy of Xinjiang Uygur Autonomous Region, People's Hospital of Xinjiang Uygur Autonomous Region, Urumqi, 830001, Xinjiang, China.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1186/s12887-024-04625-1

Clostridioides difficile infection, recurrence and the associated healthcare consumption in Sweden between 2006 and 2019

Clostridioides difficile infection, recurrence and the associated healthcare consumption in Sweden between 2006 and 2019

Fuente:Bmc Infectious Diseases

Tipo de trabajo:Estudio de cohortes

Extracto: CDI was associated with increased health consumption in all affected patient groups. The majority of the CDI burden could be contributed to hospital-acquired CDI (~ 9/10), older patients (~ 3/4) and those with multiple comorbidities (~ 6/10 Charlson score ≥ 3), with 1/5 of the total CDI burden contributed to individuals with recurrence. Yet, relatively speaking the burden was higher among the younger and those with fewer comorbidities, compared to their peers without CDI.

Claves:Clostridioides difficile, Burden, Health-economic, Healthcare consumption, Real world evidence

Cita:BMC Infect Dis 2024 May 3; 24 (1) : 468.

Autor/es:Boven, Annelies (a)
Simin, Johanna (b)

institución:(a) Centre for Translational Microbiome Research (CTMR), Department of Microbiology, Tumour and Cell Biology, Karolinska Institutet, Solnavägen 9, 171 65, Stockholm, Sweden.
(b) Department of Family Medicine and Population Health, Antwerp University, Antwerp, Belgium.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1186/s12879-024-09364-3

Acceptability and feasibility of screening with a pediatric care provider-led social determinants of health identification tool.

Acceptability and feasibility of screening with a pediatric care provider-led social determinants of health identification tool.

Fuente:Bmc Pediatrics

Extracto: Based on this study's findings, implementation of a brief provider-led screening tool into pediatric care practices may contribute to this gap.

Claves:MeSH terms: Pediatrics, MeSH terms: Social Determinants of Health, Non-MeSH terms: Screening tool

Cita:BMC Pediatr 2024 May 3; 24 (1) : 300.

Autor/es:Eyre, Alison (a)
Cohen, Janice (b)

institución:(a) Department of Family Medicine, Faculty of Medicine, University of Ottawa, Ottawa, ON, Canada. alison.eyre@aeyre.com.
(b) Centretown Community Health Centre, Ottawa, ON, Canada. alison.eyre@aeyre.com.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1186/s12887-024-04759-2

Community-based dental education in Iranian dental schools.

Community-based dental education in Iranian dental schools.

Fuente:Bmc Oral Health

Extracto: An increasing number of Iranian dental schools have integrated CBDE into their undergraduate dental curriculum. The characteristics and extent of this educational strategy vary widely among dental schools. CBDE can be more effective by making positive changes in dental programs.

Claves:Community-based dental education, Dental education, Dental students

Cita:BMC Oral Health 2024 May 3; 24 (1) : 526.

Autor/es:Bandehagh, Ata (a)
Khami, Mohammad Reza (b)

institución:(a) Research Center for Caries Prevention (RCCP), Dentistry Research Institute, Tehran University of Medical Sciences, First floor, Qods Street, Enghelab Avenue, Tehran, 1417614411, Iran.
(b) Research Center for Caries Prevention (RCCP), Dentistry Research Institute, Tehran University of Medical Sciences, First floor, Qods Street, Enghelab Avenue, Tehran, 1417614411, Iran.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1186/s12903-024-04290-x

The effect of a fermented soy beverage among patients with localized prostate cancer prior to radical prostatectomy.

The effect of a fermented soy beverage among patients with localized prostate cancer prior to radical prostatectomy.

Fuente:Bmc Urology

Extracto: Short exposure to Q-Can® among patients with localized PCa was not associated with changes in PSA levels, PCa characteristics including grade and stage or serum testosterone. Due to early termination from inability to recruit, study power, was not achieved.

Claves:Fermented soy, PSA, Prostate cancer, Randomized controlled trial

Cita:BMC Urol 2024 May 3; 24 (1) : 102.

Autor/es:Lokeshwar, Soum D (a)
Ali, Ather (b)

institución:(a) Department of Urology, Yale School of Medicine, 800 Howard Ave Fl 3, New Haven, CT, 06519, USA.
(b) Department of Pediatrics and Medicine, Yale School of Medicine, New Haven, CT, USA.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1186/s12894-024-01483-y

Sleep initiation patterns and sleep quality among toddlers in the southeast of China: initial study results.

Sleep initiation patterns and sleep quality among toddlers in the southeast of China: initial study results.

Fuente:Bmc Pediatrics

Extracto: During the COVID-19 pandemic, most infants and toddlers initiated sleep accompanied by parents and tend to have electronic media exposure before bedtime. Increased waking at night may be associated with sleep initiation with breast-feeding/bottle-feeding. Therefore, pediatric practitioners in primary community hospitals should pay attention to the education and promotion of sleep hygiene and parenting knowledge of young children to avoid the formation of poor sleep hygiene habits.

Claves:Brief infant sleep questionnaire3, Sleep Quality2, Sleep initiation pattern1, Toddler4

Cita:BMC Pediatr 2024 May 3; 24 (1) : 298.

Autor/es:Lin, Xiaoxia (a)
Chen, Xianrui (b)

institución:(a) Department of Pediatrics, Fujian Medical University Union Hospital, Fuzhou, 350001, China.
(b) Department of Pediatric Rehabilitation, Xiamen Rehabilitation Hospital, No.468 Xianyue Road, Xiamen, 36100, China. chenxianruimiao@126.com.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1186/s12887-024-04786-z

Survival benefit of radical prostatectomy in patients with advanced TURP-diagnosed prostate cancer: a population-based real-world study.

Survival benefit of radical prostatectomy in patients with advanced TURP-diagnosed prostate cancer: a population-based real-world study.

Fuente:Bmc Surgery

Extracto: Based on this retrospective population-matched study, we first found that in patients diagnosed with PCa by TURP, RP treatment may lead to a survival benefit, especially a reduction in CSM, even in old aged patients (> 75 ys.) with advanced PCa.

Claves:Elderly, Marching study, Prostate cancer, Radical prostatectomy, Survival benefit, TURP

Cita:BMC Surg 2024 May 3; 24 (1) : 134.

Autor/es:Lin, Deng (a)
Lin, Le (b)

institución:(a) Shengli Clinical Medical College of Fujian Medical University, Fuzhou, 350001, China.
(b) Department of Urology, Fujian Provincial Hospital South Branch, Fuzhou, China.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1186/s12893-024-02430-2

Early childhood caries, climate change and the sustainable development goal 13

Early childhood caries, climate change and the sustainable development goal 13

Fuente:Bmc Oral Health

Tipo de trabajo:Revisión

Extracto: The evidence on the links between SDG13 and ECC suggests that climate change may increase the risk for caries, and the management of ECC may increase environmental degradation. However, there are caries prevention strategies that can reduce the negative impact of ECC management on the environment. Context specific and inter-disciplinary research is needed to generate evidence for mitigating the negative bidirectional relationships between SDG13 and ECC.

Claves:Carbon footprints, Climate change, Dental treatment, Human security, Pediatric dentistry, Preventive dentistry, Sustainable natural resource management

Cita:BMC Oral Health 2024 May 3; 24 (1) : 524.

Autor/es:Foláyan, Morẹ Nikẹ Oluwátóyìn (a)
Schroth, Robert J (b)

institución:(a) Early Childhood Caries Advocacy Group, University of Manitoba, Winnipeg, Canada. toyinukpong@oauife.edu.ng.
(b) Department of Child Dental Health, Obafemi Awolowo University, Ile-Ife, Nigeria. toyinukpong@oauife.edu.ng.

Conflicto:Morẹ́nikẹ́ Oluwátóyìn Foláyan and Maha El Tantawi are Senior Editor Board members with BMC Oral Health. Duangporn Duangthip and Jorma Virtanen are Associate Editors. All other authors declare no conflict of interest.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1186/s12903-024-04237-2

Trainee advocacy for medical education on the care of people with intellectual and/or developmental disabilities: a sequential mixed methods analysis.

Trainee advocacy for medical education on the care of people with intellectual and/or developmental disabilities: a sequential mixed methods analysis.

Fuente:Bmc Medical Education

Extracto: Trainee advocates are influencing the development and implementation of medical education related to the care of people with intellectual and/or developmental disabilities. Their successes are influenced by engaged mentors, patient partners, and receptive institutions and their experiences provide a novel insight into the process of trainee-driven curriculum advocacy.

Claves:Curricular change, Intellectual and developmental disability, Trainee advocacy

Cita:BMC Med Educ 2024 May 3; 24 (1) : 491.

Autor/es:Clarke, Lauren (a)
O'Neill, Nora (b)

institución:(a) Stanford University School of Medicine, 291 Campus Drive, Stanford, CA, 94305, USA. clarkel@stanford.edu.
(b) Yale School of Medicine, New Haven, CT, USA.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1186/s12909-024-05449-4

A lifestyle screening tool for young children in the community: needs and wishes of parents and youth healthcare professionals.

A lifestyle screening tool for young children in the community: needs and wishes of parents and youth healthcare professionals.

Fuente:Bmc Health Services Research

Extracto: According to parents and YHCP, a new lifestyle screening tool for young children could be useful to discuss specific lifestyle topics in more detail and to provide targeted advice.

Claves:Focus groups, Lifestyle, Prevention, Toddlers, Youth healthcare

Cita:BMC Health Serv Res 2024 May 3; 24 (1) : 584.

Autor/es:Krijger, Anne (a)
Schiphof-Godart, Lieke (b)

institución:(a) Department of Neonatal and Paediatric Intensive Care, Division of Paediatric Intensive Care, Erasmus MC - Sophia Children's Hospital, PO box 2060, Rotterdam, 3000 CB, the Netherlands.
(b) Department of Public Health, Erasmus University Medical Center Rotterdam, Rotterdam, the Netherlands.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1186/s12913-024-10997-y