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Two-Month Consumption of Orange Juice Enriched with Vitamin D3 and Probiotics Decreases Body Weight, Insulin Resistance, Blood Lipids, and Arterial Blood Pressure in High-Cardiometabolic-Risk Patients on a Westernized Type Diet
Two-Month Consumption of Orange Juice Enriched with Vitamin D3 and Probiotics Decreases Body Weight, Insulin Resistance, Blood Lipids, and Arterial Blood Pressure in High-Cardiometabolic-Risk Patients on a Westernized Type Diet
Fuente:Nutrients
Tipo de trabajo:Estudio clínico aleatorizado
Extracto:
This study was
a part of FunJuice-T2EDK-01922, which was funded by the EU Regional Development
Fund and Greek National Resources.
Claves:adults, blood glucose, blood lipids, blood pressure, body weight, fruit juice, insulin resistance, probiotics, vitamin D
institución:(a) Laboratory of Dietetics and Quality of Life, Department of Food Science and Human Nutrition, School of Food and Nutritional Sciences, Agricultural University of Athens, 11855 Athens, Greece. (b) Laboratory of Dietetics and Quality of Life, Department of Food Science and Human Nutrition, School of Food and Nutritional Sciences, Agricultural University of Athens, 11855 Athens, Greece.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Targeting Aging and Longevity with Exogenous Nucleotides (TALENTs): Rationale, Design, and Baseline Characteristics from a Randomized Controlled Trial in Older Adults.
Targeting Aging and Longevity with Exogenous Nucleotides (TALENTs): Rationale, Design, and Baseline Characteristics from a Randomized Controlled Trial in Older Adults.
Fuente:Nutrients
Tipo de trabajo:Estudio aleatorizado y controlado
Extracto:
The findings of this study will contribute to our understanding of
the anti-aging effects of NTs and provide insights into their potential
applications in geriatric healthcare.
institución:(a) Department of Nutrition and Food Hygiene, School of Public Health, Peking University, Beijing 100191, China. (b) Beijing Key Laboratory of Toxicological Research and Risk Assessment for Food Safety, Peking University, Beijing 100191, China.
Conflicto:The authors don’t have any conflict of interest.
Integrated Analysis of Genomic and Genome-Wide Association Studies Identified Candidate Genes for Nutrigenetic Studies in Flavonoids and Vascular Health: Path to Precision Nutrition for (Poly)phenols.
Integrated Analysis of Genomic and Genome-Wide Association Studies Identified Candidate Genes for Nutrigenetic Studies in Flavonoids and Vascular Health: Path to Precision Nutrition for (Poly)phenols.
Fuente:Nutrients
Extracto:
In
conclusion, this integrated analysis identifies important genes to design future
nutrigenetic studies for development of precision nutrition for polyphenols.
Autor/es:Ruskovska, Tatjana (a) Postolov, Filip (b)
institución:(a) Faculty of Medical Sciences, Goce Delcev University, 2000 Stip, North Macedonia. (b) Faculty of Medical Sciences, Goce Delcev University, 2000 Stip, North Macedonia.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Long-Term Improvement in Cardiorespiratory Fitness Ameliorates Insulin Sensitivity beyond Changes in Visceral/Ectopic Fat among Men with Visceral Obesity.
Long-Term Improvement in Cardiorespiratory Fitness Ameliorates Insulin Sensitivity beyond Changes in Visceral/Ectopic Fat among Men with Visceral Obesity.
Fuente:Nutrients
Extracto:
These results support the importance of targeting VAT and
CRF/PA for the long-term management of CMR in men with visceral obesity.
institución:(a) Centre de Recherche de l'Institut Universitaire de Cardiologie et de Pneumologie de Québec-Université Laval, Québec, QC G1V 4G5, Canada. (b) Department of Kinesiology, Faculty of Medicine, Université Laval, Québec, QC G1V 0A6, Canada.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
The Impact of a Nutritional Intervention on Glycemic Control and Cardiovascular Risk Markers in Type 2 Diabetes.
The Impact of a Nutritional Intervention on Glycemic Control and Cardiovascular Risk Markers in Type 2 Diabetes.
Fuente:Nutrients
Tipo de trabajo:Estudio clínico
Extracto:
The individualized nutritional
intervention improved eating habits, anthropometric, biochemical, and
cardiovascular markers in T2D over 12 months, with sustained results during
follow-up. The dietary plan inspired by the Mediterranean and DASH diets
demonstrated good adaptation to the Brazilian food culture and the patients'
socioeconomic contexts. Consistent monitoring and personalized nutritional
management are essential for optimizing long-term outcomes. However, more
clinical trials are necessary in order to optimize the level of evidence for
longitudinal interventions.
institución:(a) Department of Hypertension, State Faculty of Medicine of São José do Rio Preto (FAMERP), São José do Rio Preto 15090-000, SP, Brazil. (b) Department of Hypertension, State Faculty of Medicine of São José do Rio Preto (FAMERP), São José do Rio Preto 15090-000, SP, Brazil.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Ecdysterone and Turkesterone-Compounds with Prominent Potential in Sport and Healthy Nutrition.
Ecdysterone and Turkesterone-Compounds with Prominent Potential in Sport and Healthy Nutrition.
Fuente:Nutrients
Extracto:
However, the therapeutic potential of phytoecdysteroid-rich extracts extends
beyond sports nutrition, with promising applications in treating chronic fatigue,
cardiovascular diseases, and neurodegenerative disorders.
institución:(a) Department of Pharmacognosy and Pharmaceutical Chemistry, Faculty of Pharmacy, Medical University-Plovdiv, 4002 Plovdiv, Bulgaria. (b) Research Institute, Medical University-Plovdiv, 4002 Plovdiv, Bulgaria.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Effects of Dietary Carbohydrate Concentration and Glycemic Index on Blood Glucose Variability and Free Fatty Acids in Individuals with Type 1 Diabetes.
Effects of Dietary Carbohydrate Concentration and Glycemic Index on Blood Glucose Variability and Free Fatty Acids in Individuals with Type 1 Diabetes.
Fuente:Nutrients
Extracto:
Different diets
may increase the risk of cardiovascular diseases by affecting GI, FFA, and blood
glucose levels.
institución:(a) Department of Nutrition and Dietetics, Faculty of Health Sciences, İstanbul Beykent University, Istanbul 34520, Turkey. (b) Institute of Health Sciences, Acibadem Mehmet Ali Aydınlar University, Istanbul 34450, Turkey.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Effect of Sustainably Sourced Protein Consumption on Nutrient Intake and Gut Health in Older Adults
Effect of Sustainably Sourced Protein Consumption on Nutrient Intake and Gut Health in Older Adults
Fuente:Nutrients
Tipo de trabajo:Revisión sistemática
Extracto:
Future research should focus on dietary
interventions combining sustainable proteins and fibre to evaluate gut barrier
function and consider inflammatory and body composition outcomes in older adults.
Claves:gut health, gut microbiota, healthy ageing, plant based diet, sustainable diet, sustainably sourced protein
Cita:Nutrients 2024 May 6; 16 (9)
Autor/es:Jones, Debra (a) Celis-Morales, Carlos (b)
institución:(a) School of Health Sciences, University of Manchester, Oxford Road, Manchester M13 9PL, UK. (b) School of Cardiovascular and Metabolic Health, University of Glasgow, Glasgow G12 8TA, UK.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Surgical choice for the treatment of partial intestinal ischemic necrosis caused by acute type a aortic dissection combined with malperfusion of superior mesenteric artery.
Surgical choice for the treatment of partial intestinal ischemic necrosis caused by acute type a aortic dissection combined with malperfusion of superior mesenteric artery.
Fuente:Journal of Cardiothoracic Surgery
Extracto:
In such cases,
prompt laparotomy and necessary necrotic bowel resection are crucial for saving
the patient's life.
Claves:Acute type a aortic dissection, Intestinal necrosis, Malperfusion syndrome, Mesenteric hypoperfusion, Treatment strategy
Cita:J Cardiothorac Surg 2024 May 11; 19 (1) : 286.
Autor/es:Yu, Wenbo (a) Liang, Yuan (b)
institución:(a) The First Clinical Medical College of Gannan Medical University, Ganzhou, 341000, China. (b) The First Clinical Medical College of Gannan Medical University, Ganzhou, 341000, China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Extracto:
To
our knowledge, we report the first case of ischemic stroke related to Danon
disease treated with endovascular treatment.
Claves:Cardiomyopathy, Case report, Danon, Lysosomal, Stroke
Cita:J Med Case Rep 2024 May 12; 18 (1) : 244.
Autor/es:Jiménez-Bolaños, Rayco (a) Hernández-Fernández, Francisco (b)
institución:(a) Department of Neurology, Complejo Hospitalario Universitario Insular-Materno Infantil de Canarias, Las Palmas, Spain. (b) Department of Neurology, Complejo Hospitalario Universitario de Albacete, C/Hermanos Falcó 37, 02006, Albacete, Spain. pacohdezfdez@hotmail.com.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Clinical predictive value of the age, creatinine, and ejection fraction score in patients in acute type A aortic dissection after total arch replacement.
Clinical predictive value of the age, creatinine, and ejection fraction score in patients in acute type A aortic dissection after total arch replacement.
Fuente:Scientific Reports
Extracto:
In conclusions, ACEF score could
be considered as a useful tool to risk stratification in patients with AAAD
before operation in daily clinical work.
Cita:Sci Rep 2024 May 11; 14 (1) : 10776.
Autor/es:Lin, Xin-Fan (a) Xie, Lin-Feng (b)
institución:(a) Department of Cardiovascular Surgery, Fujian Medical University Union Hospital, Xinquan Road 29, Fuzhou, 350001, Fujian, People's Republic of China. (b) Key Laboratory of Cardio-Thoracic Surgery (Fujian Medical University), Fujian Province University, Fuzhou, Fujian, People's Republic of China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Extracto:
Our structural findings also uncover a
zinc-binding motif that is important for NOX5 stability and enzymatic activity,
revealing modulation mechanisms of reactive oxygen species (ROS) production.
Cita:Nat Commun 2024 May 11; 15 (1) : 3994.
Autor/es:Cui, Chenxi (a) Jiang, Meiqin (b)
institución:(a) Department of Structural Biology, St Jude Children's Research Hospital, Memphis, TN38105, USA. (b) Department of Structural Biology, St Jude Children's Research Hospital, Memphis, TN38105, USA.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
institución:(a) Department of Cardiology, Hainan Provincial Hospital of Traditional Chinese Medicine, Haikou, China. (b) Department of Cardiology, Hainan Provincial Hospital of Traditional Chinese Medicine, Haikou, China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Modifiable lifestyle factors and lifetime risk of atrial fibrillation: longitudinal data from the Korea NHIS-HealS and UK Biobank cohorts.
Modifiable lifestyle factors and lifetime risk of atrial fibrillation: longitudinal data from the Korea NHIS-HealS and UK Biobank cohorts.
Fuente:Bmc Medicine
Extracto:
The overall higher lifetime risk of AF in White Europeans compared with East
Asians might be attributable to adverse lifestyle factors. Adherence to healthy
lifestyle factors was associated with the lifetime risk of AF of about 1 in 8
regardless of race/ethnicity.
Claves:Asian, Atrial fibrillation, Lifestyle factor, Lifetime risk, White
Cita:BMC Med 2024 May 13; 22 (1) : 194.
Autor/es:Park, Hanjin (a) Kim, Daehoon (b)
institución:(a) Division of Cardiology, Department of Internal Medicine, Yonsei University College of Medicine, 50-1 Yonsei-ro, Seodaemun-gu, Seoul, 03722, Republic of Korea. (b) Division of Cardiology, Department of Internal Medicine, Yonsei University College of Medicine, 50-1 Yonsei-ro, Seodaemun-gu, Seoul, 03722, Republic of Korea.
Conflicto:Boyoung Joung has served as a speaker for Bayer, BMS/Pfizer, Medtronic, and Daiichi-Sankyo and received research funds from Medtronic and Abbott. Gregory Lip has been a consultant and speaker for BMS/Pfizer, Boehringer Ingelheim, Daiichi-Sankyo, and Anthem. No fees were received personally. The remaining authors have no conflicts to declare.
Deprescribing of antidepressants: development of indicators of high-risk and overprescribing using the RAND/UCLA Appropriateness Method.
Deprescribing of antidepressants: development of indicators of high-risk and overprescribing using the RAND/UCLA Appropriateness Method.
Fuente:Bmc Medicine
Tipo de trabajo:Consenso
Extracto:
Explicit indicators of antidepressant
high-risk and overprescribing may be used directly by patients and health care
providers, and integrated within clinical decision support tools, in order to
improve the overall risk/benefit balance of this commonly prescribed class of
prescription drugs.
Claves:Adverse drug events, Antidepressants, Deprescribing, High-risk prescribing, Overprescribing
Cita:BMC Med 2024 May 13; 22 (1) : 193.
Autor/es:Brisnik, Vita (a) Vukas, Jochen (b)
institución:(a) Institute of General Practice and Family Medicine, LMU University Hospital, LMU Munich, Munich, Germany. (b) Graduate Program "POKAL - Predictors and Outcomes in Primary Care Depression Care", (DFG - GrK 2621), Munich, Germany.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Comparison of angiographic change in side-branch ostium after drug-coated balloon vs. drug-eluting stent vs. medication for the treatment of de novo coronary bifurcation lesions.
Comparison of angiographic change in side-branch ostium after drug-coated balloon vs. drug-eluting stent vs. medication for the treatment of de novo coronary bifurcation lesions.
Fuente:European Journal of Medical Research
Extracto:
In de novo coronary bifurcation lesions, DCB treatment on the MV
demonstrated favorable angiographic outcomes in the SB ostium at 6-9 month
follow-up compared to DES implantation or OMT.
institución:(a) Division of Cardiology, Department of Internal Medicine, Kangwon National University College of Medicine, Kangwon National University School of Medicine, Chuncheon, South Korea. (b) Department of Cardiology, Ulsan University Hospital, University of Ulsan College of Medicine, 877 Bangeojinsunhwan-doro, Dong-Gu, Ulsan, 44033, South Korea.
Conflicto:Bruno Scheller is a shareholder of InnoRa GmbH, Berlin, Germany. All other authors have no competing of interest to declare.
Myocardial B cells have specific gene expression and predicted interactions in dilated cardiomyopathy and arrhythmogenic right ventricular cardiomyopathy.
Myocardial B cells have specific gene expression and predicted interactions in dilated cardiomyopathy and arrhythmogenic right ventricular cardiomyopathy.
Fuente:Frontiers in Immunology
Extracto:
Naive
myocardial-associated B cells likely contribute to the pathogenesis of human DCM.
institución:(a) Division of Cardiology, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, United States. (b) Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD, United States.
Conflicto:LA is co-founder of i-Cordis, LLC, a start-up company focused on the development of immunomodulatory molecules for the treatment of heart failure, with a specific interest in derivatives of the B-cell modulating drug pirfenidone. LA is also a consultant for Kiniksa Pharmaceuticals. The remaining authors declare that the research was conducted in the absence of any commercial or financial relationships...
that could be construed as a potential conflict of interest.
Autor/es:Rezkitha, Yudith Annisa Ayu (a) Panenggak, Nur Syahadati Retno (b)
institución:(a) Doctoral Program of Medical Science, Faculty of Medicine, Universitas Airlangga, Surabaya, Indonesia. (b) Helicobacter pylori and Microbiota Study Group, Institute of Tropical Disease, Universitas Airlangga, Surabaya, Indonesia.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Blood Pressure, Readmission, and Mortality Among Patients Hospitalized With Acute Kidney Injury.
Blood Pressure, Readmission, and Mortality Among Patients Hospitalized With Acute Kidney Injury.
Fuente:Jama Network Open
Tipo de trabajo:Estudio de cohortes
Extracto:
AND RELEVANCE:
In this retrospective cohort study of post-AKI patients, there were important
time-dependent mediations of the association of blood pressure with mortality and
readmission. These findings may inform timing of post-AKI blood pressure
treatment.
Cita:JAMA Netw Open 2024 May 1; 7 (5) : e2410824.
Autor/es:Griffin, Benjamin R (a) Vaughan-Sarrazin, Mary (b)
institución:(a) Center for Access Delivery & Research and Evaluation (CADRE) Center, Iowa City VA Health Care System, Iowa City, Iowa. (b) Department of Medicine, University of Iowa Carver College of Medicine, Iowa City.
Conflicto:Conflict of Interest Disclosures: Dr Jalal reported being employed through the Department of Veterans Health Affairs. No other disclosures were reported.