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Low-density lipoprotein particle profiles compared with standard lipids measurements in the association with asymptomatic intracranial artery stenosis.
Low-density lipoprotein particle profiles compared with standard lipids measurements in the association with asymptomatic intracranial artery stenosis.
Fuente:Scientific Reports
Extracto:
These findings suggest that evaluating LDL-p levels
alongside LDL-c may aid in identifying adults at a higher risk for ICAS.
institución:(a) NCD Epidemiology Research Center, Shiga University of Medical Science, Otsu, Shiga, Japan. (b) Department of Cardiac Surgery, Cardiovascular Center, Cho Ray Hospital, Ho Chi Minh City, Vietnam.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
New evidence calls into question NICE's endocarditis prevention guidance.
New evidence calls into question NICE's endocarditis prevention guidance.
Fuente:British Dental Journal
Extracto:
Given the new evidence, a
NICE guideline review would seem appropriate so that UK high-risk patients can
receive the same protection afforded high-risk patients in the rest of the world.
Cita:Br Dent J 2024 May; 236 (9) : 702-708.
Autor/es:Thornhill, Martin (a) Prendergast, Bernard (b)
institución:(a) Professor of Translational Research in Dentistry, Unit of Oral and Maxillofacial Medicine, Surgery and Pathology, School of Clinical Dentistry, University of Sheffield, Sheffield, UK. m.thornhill@sheffield.ac.uk. (b) Professor of Cardiology, Guy´s and St Thomas´ Hospital, London and Chair of Cardiology, Cleveland Clinic, London, UK.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Prevention of infective endocarditis in at-risk patients: how should dentists proceed in 2024?
Prevention of infective endocarditis in at-risk patients: how should dentists proceed in 2024?
Fuente:British Dental Journal
Extracto:
The article also provides practical information and advice for
dentists on how to manage patients at increased IE risk who present for dental
treatment.
Cita:Br Dent J 2024 May; 236 (9) : 709-716.
Autor/es:Thornhill, Martin (a) Prendergast, Bernard (b)
institución:(a) Professor of Translational Research in Dentistry, Unit of Oral and Maxillofacial Medicine, Surgery and Pathology, School of Clinical Dentistry, University of Sheffield, Sheffield, UK. M.Thornhill@Sheffield.ac.uk. (b) Professor of Cardiology, Guy´s and St Thomas´ Hospital, London and Chair of Cardiology, Cleveland Clinic, London, UK.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
The pan-PPAR agonist lanifibranor improves cardiometabolic health in patients with metabolic dysfunction-associated steatohepatitis.
The pan-PPAR agonist lanifibranor improves cardiometabolic health in patients with metabolic dysfunction-associated steatohepatitis.
Fuente:Nature Communications
Extracto:
Here, we show that effects of lanifibranor on liver
histology in MASH are accompanied with CMH improvement, indicative of potential
cardiovascular clinical benefits.
Cita:Nat Commun 2024 May 10; 15 (1) : 3962.
Autor/es:Cooreman, Michael P (a) Butler, Javed (b)
institución:(a) Research and Development, Inventiva, New York, NY, USA. Michael.Cooreman@inventivapharma.com. (b) Research and Development, Inventiva, Daix, France. Michael.Cooreman@inventivapharma.com.
Conflicto:M.P.C., L.D., P.H.M., M.B. and P.B. are employees of Inventiva. J.L.J. is a consultant for Inventiva. D.R.B. has received honoraria from Inventiva via Translational Medicine Academy. J.B. has served as a consultant for Abbott, American Regent, Amgen, Applied Therapeutic, AskBio, Astellas, AstraZeneca, Bayer, Boehringer Ingelheim, Boston Scientific, Bristol Myers Squibb, Cardiac Dimension, Cardiocell, Cardior, Cardiorem, CSL Bearing, CVRx, Cytokinetics, Daxor,...
Edwards, Element Science, Faraday, Foundry, G3P, Innolife, Impulse Dynamics, Imbria, Inventiva, Ionis, Lexicon, Lilly, LivaNova, Janssen, Medtronics, Merck, Occlutech, Owkin, Novartis, Novo Nordisk, Pfizer, Pharmacosmos, Pharmain, Prolaio, Regeneron, Renibus, Roche, Salamandra, Sanofi, SC Pharma, Secretome, Sequana, SQ Innovation, Tenex, Tricog, Ultromics, Vifor, and Zoll. RPG received research support or honoraria form Amgen, Anthos Therapeutics, Daiichi Sankyo, Ionis, Dr. Reddy’s Laboratories, Medical Education Resources, Menarini, SAJA Pharmaceuticals, Servier, SUMMEET, and consults for Artivion, Beckman Coulter, Daiichi Sankyo, Gilead, Inari, Inventiva, PhaseBio Pharmaceuticals, Samsung and Aventis. FZ reports personal fees from 89Bio, Abbott, Acceleron, Applied Therapeutics, Bayer, Betagenon, Boehringer, BMS, CVRx, Cambrian, Cardior, Cereno pharmaceutical, Cellprothera, CEVA, Inventiva, KBP, Merck, NovoNordisk, Owkin, Otsuka, Roche Diagnostics, Northsea, USa2, having stock options at G3Pharmaceutical and equities at Cereno, Cardiorenal, Eshmoun Clinical research and being the founder of Cardiovascular Clinical Trialists. MFA received grants from Boehringer-Ingelheim, Gilead, Hanmi, Inventiva, Madrigal, Novo Nordisk; honoraria from Clinical Care Options, Fishawack, Medscape, Terra Firma, CLDF; royalties from Up-to-Date; consults for 89Bio, BMS, Hanmi, Inventiva, Intercept, Madrigal, Merck, Novo Nordisk. SMF received grants from Astellas, Falk Pharma, Genfit, Gilead Sciences, GlympsBio, Janssens Pharmaceutica, Inventiva, Merck Sharp & Dome, Pfizer, Roche; honoraria from Abbvie, Allergan, Bayer, Eisai, Genfit, Gilead Sciences, Janssens Cilag, Intercept, Inventiva, Merck Sharp & Dome, Novo Nordisk, Promethera, Siemens; serves as consultant for Abbvie, Actelion, Aelin Therapeutics, AgomAb, Aligos Therapeutics, Allergan, Alnylam, Astellas, Astra Zeneca, Bayer, Boehringer Ingelheim, Bristoll-Meyers Squibb, CSL Behring, Coherus, Echosens, Dr. Falk Pharma, Eisai, Enyo, Galapagos, Galmed, Genetech, Genfit, Genflow Biosciences, Gilead Sciences, Intercept, Inventiva, Janssens Pharmaceutica, PRO.MED.CS Praha, Julius Clinical, Madrigal, Medimmune, Merck Sharp & Dome, Mursla Bio, NGM Bio, Novartis, Novo Nordisk, Promethera, Roche, Siemens Healthineers.
A systematic review of thromboembolic complications and outcomes in hospitalised COVID-19 patients.
A systematic review of thromboembolic complications and outcomes in hospitalised COVID-19 patients.
Fuente:Bmc Infectious Diseases
Extracto:
Therefore, every
patient should be assessed for the risk of thromboembolic complications and
provided with an appropriate thromboprophylaxis management plan tailored to their
individual needs.
Autor/es:Othman, Hanies Yuhana (a) Zaki, Izzati Abdul Halim (b)
institución:(a) Department of Clinical Pharmacy, Fakulti Farmasi, Universiti Teknologi MARA Cawangan Selangor, Kampus Puncak Alam, Bandar Puncak Alam, Selangor, Malaysia. (b) Department of Clinical Pharmacy, Fakulti Farmasi, Universiti Teknologi MARA Cawangan Selangor, Kampus Puncak Alam, Bandar Puncak Alam, Selangor, Malaysia.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Lipids as potential mediators linking body mass index to diabetes: evidence from a mediation analysis based on the NAGALA cohort.
Lipids as potential mediators linking body mass index to diabetes: evidence from a mediation analysis based on the NAGALA cohort.
Fuente:Bmc Endocrine Disorders
Extracto:
Our fresh findings
suggested that lipid parameters partially mediated the association of BMI with
diabetes risk; this result indicated that in the context of diabetes risk
screening and disease management, it is important to not only monitor BMI but
also pay attention to lipid parameters, particularly HDL-C and HDL-C-related
lipid ratio parameters.
Claves:Body mass index, Diabetes, Indirect effect, Lipid parameters, Mediation analyses
Cita:BMC Endocr Disord 2024 May 10; 24 (1) : 66.
Autor/es:Lu, Song (a) Wang, Qun (b)
institución:(a) Department of Cardiology, The First Affiliated Hospital of Nanchang University, Jiangxi Medical College, Nanchang University, Nanchang, 330006, China. (b) Jiangxi Cardiovascular Research Institute, Jiangxi Provincial People's Hospital, The First Affiliated Hospital of Nanchang Medical College, Nanchang, 330006, China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
institución:(a) Affiliated Hospital of Huanghuai University, Zhumadian Central Hospital, Zhumadian, 463000, He'nan, People's Republic of China. renyongcheng@huanghuai.edu.cn. (b) Institute of Health Data Management, Huanghuai University, Zhumadian, 463000, He'nan, People's Republic of China. renyongcheng@huanghuai.edu.cn.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Anaesthesia management of a patient with Bethlem Myopathy for elective tonsillectomy
Anaesthesia management of a patient with Bethlem Myopathy for elective tonsillectomy
Fuente:Bmc Anesthesiology
Tipo de trabajo:Caso clínico
Extracto:
Bethlem
Myopathy, while often exhibiting a mild clinical course, can present anaesthetic
challenges. Awareness of potential complications including a difficult airway,
cardiovascular and respiratory implications as well as the need for specialised
monitoring and positioning is crucial to ensure a safe peri-operative course.
Association between life's essential 8 and frailty status among cancer survivors in the United States: a cross-sectional analysis.
Association between life's essential 8 and frailty status among cancer survivors in the United States: a cross-sectional analysis.
Fuente:Bmc Public Health
Extracto:
Studies have found that the higher the LE8 score, the less likely a
cancer patient is to develop debilitating symptoms.This indicates that the LE8
scores may provide an opportunity for interventions aimed at improving the
prognosis of cancer patients.
Cita:BMC Public Health 2024 May 10; 24 (1) : 1287.
Autor/es:Qiu, Xiuxiu (a) Wu, Qidong (b)
institución:(a) Department of Oncology, Longhua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, China. (b) Department of Intensive Care Unit, Longhua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Potential impact of blood cholesterol guidelines on statin treatment in the U.S. population using interrupted time series analysis.
Potential impact of blood cholesterol guidelines on statin treatment in the U.S. population using interrupted time series analysis.
Fuente:Bmc Cardiovascular Disorders
Tipo de trabajo:Guía
Extracto:
The 2013 ACA/AHA Guideline release is associated with trend
improvements in the long-term MACE Survival for Diabetes group and optimal statin
use for ASCVD group. These significant associations might indicate a potential
positive long-term impact of the 2013 ACA/AHA Guideline on better health outcomes
for primary prevention groups and an immediate potential impact on statin
prescribing behaviors in higher-at-risk groups. However, further investigation is
required to confirm the causal effect of the 2013 ACA/AHA Guideline.
Claves:Cardiovascular disease, Diabetes, Generic atorvastatin, Guideline implementation, Interrupted time series analysis, Long-term effect, MACE, Policy effect
Cita:BMC Cardiovasc Disord 2024 May 10; 24 (1) : 245.
Autor/es:Yew, Pui Ying (a) Loth, Matt (b)
institución:(a) Institute for Health Informatics, University of Minnesota, Minneapolis, MN, USA. (b) Institute for Health Informatics, University of Minnesota, Minneapolis, MN, USA.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Differences in provider approach to initiating and titrating guideline directed medical therapy in heart failure with reduced ejection fraction.
Differences in provider approach to initiating and titrating guideline directed medical therapy in heart failure with reduced ejection fraction.
Fuente:Bmc Cardiovascular Disorders
Tipo de trabajo:Guía
Extracto:
Our results demonstrate cardiologists were more likely to adjust GDMT than
general medicine physicians. Future focus on improving GDMT prescribing should
target providers other than cardiologists to improve care in patients with HFrEF.
Claves:Evidence-based therapy, Guideline-directed medical therapy (GDMT), Heart failure with reduced ejection fraction (HFrEF), Medications
Cita:BMC Cardiovasc Disord 2024 May 11; 24 (1) : 247.
Autor/es:Cordwin, David J (a) Guidi, Jessica (b)
institución:(a) College of Pharmacy, University of Michigan, Ann Arbor, MI, USA. (b) Medical School, University of Michigan, Ann Arbor, MI, USA.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Analysis of onset-to-door time and its influencing factors in Chinese patients with acute ischemic stroke during the 2020 COVID-19 epidemic: a preliminary, prospective, multicenter study.
Analysis of onset-to-door time and its influencing factors in Chinese patients with acute ischemic stroke during the 2020 COVID-19 epidemic: a preliminary, prospective, multicenter study.
Fuente:Bmc Health Services Research
Extracto:
Most patients
with AIS fail to reach a hospital within the critical 3-h window. The following
measures are recommended to reduce pre-hospital delays: reasonable distribution
of hospitals accessible to nearby residents, minimizing interhospital transfer,
paying attention to patients with mild stroke, and encouraging patients to use
ambulance services. Pre-hospital delays for patients can be reduced by
implementing these measures, ultimately improving the timeliness of treatment and
enhancing patient prognosis. This study was carried out amid the COVID-19
pandemic, which presented challenges and constraints.
Claves:Acute ischemic stroke, China, Current situation, Onset-to-door time, Pre-hospital delay, Risk factors
Cita:BMC Health Serv Res 2024 May 10; 24 (1) : 615.
Autor/es:Liao, Yuqi (a) Qi, Wenwei (b)
institución:(a) School of Medicine, Shenzhen University, Shenzhen, China. (b) National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing, China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Laboratory-based surveillance of chronic kidney disease in people with private health coverage in Brazil.
Laboratory-based surveillance of chronic kidney disease in people with private health coverage in Brazil.
Fuente:Bmc Nephrology
Tipo de trabajo:Guía
Extracto:
The estimated prevalence of CKD was 3.8%, and approximately 10% of
the participants were in the categories of high or very high-risk of the disease.
While almost 20% of beneficiaries with PHC had serum creatinine data, fewer than
1% underwent tests for proteinuria. This study was one of the largest ever
conducted in Brazil and the first one to use the 2021 CKD-EPI equation to
estimate the prevalence of CKD.
Claves:Chronic kidney disease, Epidemiology, Information systems in clinical laboratory, Prevalence, Supplementary health
institución:(a) Department of High Complexity Patients, Hapvida NotreDame Intermédica, Rua Hipódromo, 987 - Mooca, São Paulo, SP, 03164-140, Brazil. farid_samaan@yahoo.com.br. (b) Secretaria de Estado da Saúde de São Paulo, São Paulo, SP, Brazil. farid_samaan@yahoo.com.br.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Comparison between catheter ablation versus permanent pacemaker implantation as an initial treatment for tachycardia-bradycardia syndrome patients: a prospective, randomized trial.
Comparison between catheter ablation versus permanent pacemaker implantation as an initial treatment for tachycardia-bradycardia syndrome patients: a prospective, randomized trial.
Fuente:Bmc Cardiovascular Disorders
Extracto:
CA had a similar
efficacy and safety profile with that of PM and a higher sinus rhythm maintenance
rate. CA could be considered as a preferable initial treatment option over PM
implantation in patients with paroxysmal AF and TBS. TRIAL REGISTRATION:
KCT0000155.
Cita:BMC Cardiovasc Disord 2024 May 10; 24 (1) : 246.
Autor/es:Cho, Min Soo (a) Lee, Ji Hyun (b)
institución:(a) Department of Cardiology, Heart Institute, Asan Medical Center, University of Ulsan College of Medicine, 88, Olympic-ro 43-gil, Songpa-gu, Seoul, 05505, Korea. (b) Cardiovascular Center, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Seongnam, Korea.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Insight into the research history and trends of total anomalous pulmonary venous connection: a bibliometric analysis.
Insight into the research history and trends of total anomalous pulmonary venous connection: a bibliometric analysis.
Fuente:Journal of Cardiothoracic Surgery
Tipo de trabajo:Caso clínico
Extracto:
This study conducted a bibliometric analysis to provide a
comprehensive overview of TAPVC research. We hope to offer new ideas for
promoting development in the field of TAPVC.
Claves:Bibliometrics, CiteSpace, Hot spot, Research progress, Total anomalous pulmonary venous connection, VOSViewer
Cita:J Cardiothorac Surg 2024 May 11; 19 (1) : 285.
Autor/es:Wen, Chen (a) Shen, Geng (b)
institución:(a) Department of Cardiothoracic Surgery, Shanghai Children's Medical Center, School of Medicine, Shanghai Jiao Tong University, Shanghai, China. wenchen1993@sjtu.edu.cn. (b) Division of Cardiology, Peking University First Hospital, Beijing, China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Association of RASGRP1 polymorphism with vascular complications in Chinese diabetic patients with glycemic control and antihypertensive treatment.
Association of RASGRP1 polymorphism with vascular complications in Chinese diabetic patients with glycemic control and antihypertensive treatment.
Fuente:Cardiovascular Diabetology
Extracto:
We found that
patients with G allele of RASGRP1 (rs56254815) showed a better antihypertensive
therapy efficacy in T2DM patients. The rs7403531 T allele could reduce the risk
of major microvascular events and major eye diseases in T2DM patients receiving
either hypoglycemic or antihypertensive therapy. Our findings suggest that
RASGRP1 genetic polymorphism might predict the cardiovascular complications in
T2DM patients.
Claves:Individual drug treatment, Polymorphism, RASGRP1, Type 2 diabetes, Vascular complications, rs7403531
Cita:Cardiovasc Diabetol 2024 May 10; 23 (1) : 166.
Autor/es:Zhou, Jiecan (a) Xu, Bo (b)
institución:(a) The First Affiliated Hospital, Hunan Provincial Clinical Medical Research Center for Drug Evaluation of Major Chronic Diseases, Hengyang Medical School, University of South China, 421001, Hengyang, Hunan, China. zhoujiecan@fsyy.usc.edu.cn. (b) The First Affiliated Hospital, Hengyang Clinical Pharmacology Research Center, Hengyang Medical School, University of South China, 421001, Hengyang, Hunan, China. zhoujiecan@fsyy.usc.edu.cn.
Conflicto:All authors declare no conflict of interest relevant to the subject matter or materials discussed in the article.
Prognostic value of metabolic dysfunction-associated steatotic liver disease over coronary computed tomography angiography findings: comparison with no-alcoholic fatty liver disease.
Prognostic value of metabolic dysfunction-associated steatotic liver disease over coronary computed tomography angiography findings: comparison with no-alcoholic fatty liver disease.
Fuente:Cardiovascular Diabetology
Extracto:
Patients with MASLD are
likely to have a higher risk of cardiovascular disease than those with NAFLD.
Concurrent assessment of MASLD during CCTA improves the identification of
patients at a higher risk of cardiovascular disease among those with clinically
indicated CCTA.
Contributions of elevated CRP, hyperglycaemia, and type 2 diabetes to cardiovascular risk in the general population: observational and Mendelian randomization studies.
Contributions of elevated CRP, hyperglycaemia, and type 2 diabetes to cardiovascular risk in the general population: observational and Mendelian randomization studies.
Fuente:Cardiovascular Diabetology
Extracto:
Elevated concentrations of
plasma CRP and glucose are predictors of IHD and CVD death in the general
population. We found no genetic association between CRP and glucose, or vice
versa, suggesting that lowering glucose pharmacologically does not have a direct
effect on low-grade inflammation.
Cita:Cardiovasc Diabetol 2024 May 10; 23 (1) : 165.
Autor/es:Rolver, Monica G (a) Emanuelsson, Frida (b)
institución:(a) Department of Clinical Biochemistry, Copenhagen University Hospital - Herlev Gentofte, Borgmester Ib Juuls Vej 1, Herlev, 2730, Denmark. (b) Institute of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Blegdamsvej 3B, Copenhagen, 2200, Denmark.
Conflicto:Monica Gylling Rolver is part-time employed by Novo Nordisk Denmark as a student assistant. Other authors report no conflict of interest related to the present study.
Association of neutrophil-lymphocyte ratio with all-cause and cardiovascular mortality in US adults with diabetes and prediabetes
Association of neutrophil-lymphocyte ratio with all-cause and cardiovascular mortality in US adults with diabetes and prediabetes
Fuente:Bmc Endocrine Disorders
Tipo de trabajo:Estudio de cohortes
Extracto:
The findings of this
prospective cohort study conducted in the US indicate a positive association of
elevated NLR levels with heightened risks of overall and cardiovascular mortality
among adults with diabetes and prediabetes. However, potential confounding
factors for NLR and the challenge of monitoring NLR's fluctuations over time
should be further focused.
institución:(a) Department of Endocrinology and Metabolism, Guangzhou Red Cross Hospital, Jinan University, Guangzhou, 510220, Guangdong, China. (b) State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, 510120, China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Enhanced external counterpulsation treatment improves multi-organ hemodynamics for postoperative liver transplantation patient. A case report.
Enhanced external counterpulsation treatment improves multi-organ hemodynamics for postoperative liver transplantation patient. A case report.
Fuente:Journal of Cardiothoracic Surgery
Extracto:
We report a case of
multi-organ ischemic symptoms in a post LT patient. EECP treatment can
significantly improve the quality of life via the systematic promotion of
hemodynamics.
Cita:J Cardiothorac Surg 2024 May 10; 19 (1) : 284.
Autor/es:Zeng, Xinchen (a) Jin, Xin (b)
institución:(a) Department of Liver Surgery, The Third People's Hospital of Shenzhen, Shenzhen, 518112, China. (b) Department of Liver Surgery, The Third People's Hospital of Shenzhen, Shenzhen, 518112, China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación