The endothelium: gatekeeper to lung ischemia-reperfusion injury.

The endothelium: gatekeeper to lung ischemia-reperfusion injury.

Fuente:Respiratory Research

Extracto: The application of therapies targeting the pulmonary endothelium may help to halt this rapid and potentially fatal injury.

Claves:Endothelial barrier dysfunction, Glycocalyx, Inflammation, Ion channels, Ischemia-reperfusion injury, Lung transplantation, Oxidative stress, TRPV4

Cita:Respir Res 2024 Apr 18; 25 (1) : 172.

Autor/es:Ta, Huy Q (a)
Kuppusamy, Maniselvan (b)

institución:(a) Department of Surgery, University of Virginia, P. O. Box 801359, Charlottesville, VA, 22908, USA.
(b) Robert M. Berne Cardiovascular Research Center, University of Virginia, Charlottesville, VA, 22908, USA.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1186/s12931-024-02776-4

Longitudinal blood glucose level and increased silent myocardial infarction: a pooled analysis of four cohort studies.

Longitudinal blood glucose level and increased silent myocardial infarction: a pooled analysis of four cohort studies.

Fuente:Cardiovascular Diabetology

Extracto: Higher longitudinal FG and larger intra-individual variability in FG over time were associated in a dose-response manner with a higher SMI risk. These findings support the significance of routine cardiac screening for subjects with elevated FG, with and without diabetes.

Claves:Diabetes, Intra-individual FG variability, Longitudinal fasting glucose (FG), Silent myocardial infarction

Cita:Cardiovasc Diabetol 2024 Apr 18; 23 (1) : 130.

Autor/es:Xiao, Mianli (a)
Malmi, Markku A Jr (b)

institución:(a) College of Public Health, University of South Florida, Tampa, FL, USA.
(b) College of Public Health, University of South Florida, Tampa, FL, USA.

Conflicto:No potential conflicts of interest relevant to this article were reported.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1186/s12933-024-02212-3

Gender differences in the relationship between serum uric acid and the long-term prognosis in heart failure: a nationwide study.

Fuente:Cardiovascular Diabetology

Extracto: Gender differences in the association between SUA and long-term prognosis of HF existed. SUA was an independent prognostic predictor for long-term outcomes of HF in men, but not in women.

Claves:Gender medicine, Heart failure, Prognosis, Uric acid

Cita:Cardiovasc Diabetol 2024 Apr 18; 23 (1) : 131.

Autor/es:Fu, Kang (a)
Cheng, Congyi (b)

institución:(a) State Key Laboratory for Innovation and Transformation of Luobing Theory, Key Laboratory of Cardiovascular Remodeling and Function Research, Chinese Ministry of Education, Chinese National Health Commission and Chinese Academy of Medical Sciences; Department of Cardiology, Qilu Hospital of Shandong University, Jinan, China.
(b) State Key Laboratory for Innovation and Transformation of Luobing Theory, Key Laboratory of Cardiovascular Remodeling and Function Research, Chinese Ministry of Education, Chinese National Health Commission and Chinese Academy of Medical Sciences; Department of Cardiology, Qilu Hospital of Shandong University, Jinan, China.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1186/s12933-024-02214-1

Associations between 47 anthropometric markers derived from a body scanner and relative fat-free mass in a population-based study.

Associations between 47 anthropometric markers derived from a body scanner and relative fat-free mass in a population-based study.

Fuente:Bmc Public Health

Extracto: Anthropometric measures were more strongly associated with FFM(ADP) compared to FFM(BIA). Anthropometric markers like circumferences of the high or middle hip, belly or waist may be appropriate surrogates for FFM to aid in individualized therapy. Given that the identified markers are representative of visceral adipose tissue, the connection between whole body strength as surrogate for FFM and fat mass should be explored in more detail.

Claves:Body surface scan, anthropometric parameters, Cardiovascular disease, Epidemiology, Fat free mass, Population-based study

Cita:BMC Public Health 2024 Apr 18; 24 (1) : 1079.

Autor/es:Dietzmann, Maximilian (a)
Radke, Dörte (b)

institución:(a) Institute for Community Medicine, University Medicine Greifswald, Walther Rathenau Str. 48, D-17475, Greifswald, Germany.
(b) Institute for Community Medicine, University Medicine Greifswald, Walther Rathenau Str. 48, D-17475, Greifswald, Germany.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1186/s12889-024-18611-w

Modern software and physical education: can online training enhance gym training?

Modern software and physical education: can online training enhance gym training?

Fuente:Bmc Medical Education

Extracto: The findings of the study contribute to the data synthesis on the expediency of using modern software in physical education.

Claves:Motivation, Physical activity, Physical education, Sprint, Squat jump, Technology, University students

Cita:BMC Med Educ 2024 Apr 18; 24 (1) : 419.

Autor/es:Ge, Linna (a)
Li, Menglu (b)

institución:(a) Institute of Physical Education, Yancheng Institute of Technology, Yancheng, Jiangsu, China.
(b) Institute of Physical Education, Yancheng Institute of Technology, Yancheng, Jiangsu, China.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1186/s12909-024-05345-x

Elevated serum B-cell activator factor levels predict rapid progressive interstitial lung disease in anti-melanoma differentiation associated protein 5 antibody positive dermatomyositis.

Elevated serum B-cell activator factor levels predict rapid progressive interstitial lung disease in anti-melanoma differentiation associated protein 5 antibody positive dermatomyositis.

Fuente:Orphanet Journal of Rare Diseases

Extracto: Serum BAFF could be a useful prognostic biomarker for early detecting RP-ILD risk in anti-MDA5(+)DM patients.

Claves:Biomarker, Dermatomyositis, Melanoma differentiation-associated protein 5 antibody, Rapidly progressive interstitial lung disease, Serum B cell activating factor

Cita:Orphanet J Rare Dis 2024 Apr 19; 19 (1) : 170.

Autor/es:Shi, Yumeng (a)
You, Hanxiao (b)

institución:(a) Department of Rheumatology, The First Affiliated Hospital of Nanjing Medical University, No. 300, Guangzhou Road, Gulou District, Nanjing, 210029, China.
(b) Department of Rheumatology, The First Affiliated Hospital of Nanjing Medical University, No. 300, Guangzhou Road, Gulou District, Nanjing, 210029, China.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1186/s13023-024-03153-6

Clinical features of plastic bronchitis in children after congenital heart surgery.

Clinical features of plastic bronchitis in children after congenital heart surgery.

Fuente:Italian Journal of Pediatrics

Tipo de trabajo:Estudio de cohortes

Extracto: Children with airway abnormalities or right ventricular dysfunction after CHS should be alerted to the development of PB. Pharmacological treatment such as anti-infection, corticosteroids, or improvement of right ventricular function is the basis of PB treatment, while fiberoptic bronchoscopy is an essential tool for the diagnosis and treatment of PB. ECMO assistance is a vital salvage treatment for recurrent critically ill PB patients.

Claves:Airway abnormalities, Children, Congenital heart surgery, Fiberoptic bronchoscopy, Plastic bronchitis

Cita:Ital J Pediatr 2024 Apr 19; 50 (1) : 74.

Autor/es:Zhu, Li-Min (a)
Li, Chun-Xiang (b)

institución:(a) Department of Cardiac Intensive Care Unit, Shanghai Children' s Medical Center, Shanghai Jiaotong University School of Medicine, 1678 Dongfang Road, 200127, Shanghai, PR China.
(b) Department of Cardiac Intensive Care Unit, Shanghai Children' s Medical Center, Shanghai Jiaotong University School of Medicine, 1678 Dongfang Road, 200127, Shanghai, PR China.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1186/s13052-024-01650-9

Potential application of mesenchymal stromal cells as a new therapeutic approach in acute respiratory distress syndrome and pulmonary fibrosis.

Potential application of mesenchymal stromal cells as a new therapeutic approach in acute respiratory distress syndrome and pulmonary fibrosis.

Fuente:Respiratory Research

Extracto: Although further investigations and shared protocols are still needed, the safety of MSC therapy has been recurrently shown, and its potential in treating ARDS and preventing PF might represent a new therapeutic strategy.

Claves:ARDS, Acute respiratory distress syndrome, COVID-19, Mesenchymal stromal cells, Pulmonary fibrosis

Cita:Respir Res 2024 Apr 18; 25 (1) : 170.

Autor/es:Gazzaniga, Giulia (a)
Voltini, Marta (b)

institución:(a) SC Anestesia e Rianimazione 2, Fondazione IRCCS Policlinico San Matteo, Viale Camillo Golgi 19, Pavia, PV, 27100, Italy. giulia.gazzaniga@libero.it.
(b) Department of Clinical-Surgical, Diagnostic and Pediatric Sciences, University of Pavia, Pavia, Italy. giulia.gazzaniga@libero.it.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1186/s12931-024-02795-1

Tri-ponderal mass index and left ventricular hypertrophy in a cohort of caucasian children and adolescents with obesity.

Tri-ponderal mass index and left ventricular hypertrophy in a cohort of caucasian children and adolescents with obesity.

Fuente:Italian Journal of Pediatrics

Extracto: Left ventricular remodeling is associated with the cardio-metabolic risk markers WC and WHR, but not with the adiposity index TMI among children with obesity.

Claves:Cardiovascular risk, Left ventricular hypertrophy, Left ventricular mass index, Pediatric obesity, Tri-ponderal mass index

Cita:Ital J Pediatr 2024 Apr 19; 50 (1) : 75.

Autor/es:Vizzuso, Sara (a)
Torto, Alberico Del (b)

institución:(a) Department of Pediatrics, Buzzi Children's Hospital, University of Milan, Milan, Italy. sara.vizzuso@asst-fbf-sacco.it.
(b) Centro Cardiologico Monzino IRCCS, Milan, Italy.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1186/s13052-024-01634-9

Pregnancy outcomes of Fabry disease in Austria (PROFABIA)-a retrospective cohort-study.

Pregnancy outcomes of Fabry disease in Austria (PROFABIA)-a retrospective cohort-study.

Fuente:Orphanet Journal of Rare Diseases

Extracto: Our cohort-study in women with Fabry disease shows an increase of pain burden during pregnancies and clearly points to an increased risk for preeclampsia, prematurity, and neonates small for gestational age. With a substantial number of high-risk pregnancies, neonatal outcomes are somewhat worse in Fabry disease than in the general public. Thus, we provide valuable data enabling informed decision-making in pregnancy counselling for Fabry disease.

Claves:Delivery outcomes, Fabry disease, Lysosomal storage disorders, Pregnancy, Pregnancy counselling, Pregnancy outcomes

Cita:Orphanet J Rare Dis 2024 Apr 18; 19 (1) : 165.

Autor/es:Haninger-Vacariu, Natalja (a)
Anastopoulos, Kyra (b)

institución:(a) Division of Nephrology and Dialysis, Department of Medicine III, Medical University of Vienna, Währinger Gürtel 18-20, Vienna, 1090, Austria. natalja.haninger@meduniwien.ac.at.
(b) University of Vienna, Vienna, Austria.

Conflicto:GSP, CG, MP received honoraria and travel support from Amicus Therapeutics. MP has participated in meetings sponsored by, received speaker or consulting honoraria or travel funding from Amicus, Merck, Novartis and Sanofi-Genzyme. CG received honoraria and travel support from Amicus Therapeutics, Sanofi-Aventis and Takeda pharmaceuticals.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1186/s13023-024-03180-3

Data-driven clustering approach to identify novel clusters of high cognitive impairment risk among Chinese community-dwelling elderly people with normal cognition

Data-driven clustering approach to identify novel clusters of high cognitive impairment risk among Chinese community-dwelling elderly people with normal cognition

Fuente:Journal of Global Health

Tipo de trabajo:Estudio de cohortes

Extracto: A data-driven approach can be instrumental in identifying individuals at high risk of cognitive impairment among cognitively normal elderly populations. Based on various sociodemographic features, these clusters can suggest individualised intervention plans.

Cita:J Glob Health 2024 Apr 19; 14 : 04088.

Autor/es:Ran, Wang (a)
Yu, Qiutong (b)

institución:(a) Zhejiang Provincial People's Hospital, People's Hospital of Hangzhou Medical College, Hangzhou, China.
(b) Medical Education Department, Zhejiang Provincial People's Hospital, People's Hospital of Hangzhou Medical College, Hangzhou, China.

Conflicto:Disclosure of interest: The authors completed the ICMJE Disclosure of Interest Form (available upon request from the corresponding author) and disclose no relevant interests.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Scotland

Sitio web:http://dx.doi.org/10.7189/jogh.14.04088

Hair cortisol and changes in cortisol dynamics in chronic kidney disease.

Hair cortisol and changes in cortisol dynamics in chronic kidney disease.

Fuente:Frontiers in Endocrinology

Extracto: Cortisol-after-DST and salivary cortisol rhythm present progressive alterations in CKD patients. Changes in cortisol excretion and HPA dynamics in CKD are not accompanied by significant changes in long-term exposure to cortisol evaluated by HC. The clinical significance and pathophysiological mechanisms explaining the associations between HPA parameters, body composition, and kidney damage warrant further study.

Claves:cardiovascular risk, chronic kidney disease, dexamethasone suppression test, hair cortisol, salivary cortisol, visceral adipose tissue

Cita:Front Endocrinol (Lausanne) 2024; 15 : 1282564.

Autor/es:Boswell, Laura (a)
Vega-Beyhart, Arturo (b)

institución:(a) Endocrinology and Nutrition Department, Hospital Clínic de Barcelona, Barcelona, Spain.
(b) Group of Endocrine Disorders, Institut d'Investigacions Biomèdiques August Pi Sunyer (IDIBAPS), Barcelona, Spain.

Conflicto:The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3389/fendo.2024.1282564

Risk factors for erectile dysfunction in diabetes mellitus

Fuente:Frontiers in Endocrinology

Tipo de trabajo:Revisión sistemática

Extracto: Our study indicates that in men with DM, several risk factors for ED have been identified, including mean age, HbA1C, duration of DM, diabetic neuropathy, diabetic retinopathy, diabetic foot, cardiovascular disease, hypertension, microvascular disease, vascular disease, nephropathy, depression, metabolic syndrome, and diuretic treatment. By clarifying the connection between these risk factors and ED, clinicians and scientific experts can intervene and address these risk factors, ultimately reducing the occurrence of ED and improving patient management.

Claves:diabetes mellitus, erectile dysfunction, meta-analysis, risk factors, sexual dysfuction

Cita:Front Endocrinol (Lausanne) 2024; 15 : 1368079.

Autor/es:Dilixiati, Diliyaer (a)
Waili, Alapati (b)

institución:(a) Department of Urology, First Affiliated Hospital of Xinjiang Medical University, Urumqi, China.
(b) Department of Pancreatic Surgery, First Affiliated Hospital of Xinjiang Medical University, Urumqi, China.

Conflicto:The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3389/fendo.2024.1368079

Prediction of glycosylated hemoglobin level in patients with cardiovascular diseases and type 2 diabetes mellitus with respect to anti-diabetic medication.

Fuente:Frontiers in Endocrinology

Extracto: The resulting algorithms could be used to assist clinical decision-making on prescribing anti-diabetic medications in pursuit of achieving glycemic control.

Claves:diabetes mellitus, glycosylated hemoglobin, metformin, random forest, sitagliptin

Cita:Front Endocrinol (Lausanne) 2024; 15 : 1305640.

Autor/es:Ikramov, Alisher (a)
Mukhtarova, Shakhnoza (b)

institución:(a) Department of Mathematics, New Uzbekistan University, Tashkent, Uzbekistan.
(b) Department of Applied Mathematics and Information Security, National University of Uzbekistan, Tashkent, Uzbekistan.

Conflicto:The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3389/fendo.2024.1305640

Tumor lymphangiogenesis index reveals the immune landscape and immunotherapy response in lung adenocarcinoma.

Tumor lymphangiogenesis index reveals the immune landscape and immunotherapy response in lung adenocarcinoma.

Fuente:Frontiers in Immunology

Extracto: Overall, we confirmed that the LYM index is a prognostic risk factor and a valuable predictor of immunotherapy response in LUAD patients, which provides new evidence for the potential application of LYM.

Claves:immune cell infiltration, immunotherapy, lung adenocarcinoma, lymphangiogenesis, prognosis

Cita:Front Immunol 2024; 15 : 1354339.

Autor/es:Yang, Weichang (a)
Wu, Zhijian (b)

institución:(a) Department of Respiratory and Critical Care Medicine, The Second Affiliated Hospital of Nanchang University, Jiangxi Medical College, Nanchang University, Nanchang, Jiangxi, China.
(b) Jiangxi Key Laboratory of Molecular Medicine, Nanchang, Jiangxi, China.

Conflicto:The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3389/fimmu.2024.1354339

Endoplasmic reticulum stress: bridging inflammation and obesity-associated adipose tissue.

Fuente:Frontiers in Immunology

Extracto: In this review, we comprehensively elucidate the mechanisms by which ERS impacts adipose tissue function and inflammation in obesity, aiming to offer insights into targeting ERS for ameliorating metabolic dysregulation in obesity-associated chronic diseases such as hyperlipidemia, hypertension, fatty liver, and type 2 diabetes.

Claves:adipose tissue, endoplasmic reticulum stress, inflammation, metabolic disorder, obesity

Cita:Front Immunol 2024; 15 : 1381227.

Autor/es:Ma, Kaile (a)
Zhang, Yanjiao (b)

institución:(a) Institute of Metabolic Diseases, Guang'anmen Hospital, China Academy of Chinese Medical Sciences, Beijing, China.
(b) Institute of Metabolic Diseases, Guang'anmen Hospital, China Academy of Chinese Medical Sciences, Beijing, China.

Conflicto:The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3389/fimmu.2024.1381227

Systemic immune-inflammation index and all-cause and cause-specific mortality in sarcopenia: a study from National Health and Nutrition Examination Survey 1999-2018.

Fuente:Frontiers in Immunology

Extracto: Our study is the first to demonstrate a significant relationship between SII and increased mortality risks in a sarcopenia population.

Claves:NHANES, mortality, population-based study, sarcopenia, systemic immune-inflammation index

Cita:Front Immunol 2024; 15 : 1376544.

Autor/es:Zeng, Qing-Yue (a)
Qin, Yu (b)

institución:(a) General Practice Ward/International Medical Center Ward, General Practice Medical Center, National Clinical Research Center for Geriatrics, West China Hospital, Sichuan University, Chengdu, Sichuan, China.
(b) General Practice Ward/International Medical Center Ward, General Practice Medical Center, National Clinical Research Center for Geriatrics, West China Hospital, Sichuan University, Chengdu, Sichuan, China.

Conflicto:The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3389/fimmu.2024.1376544

Can blood eosinophil count be used as a predictive marker for the severity of COPD and concomitant cardiovascular disease? The relationship with the 2023 Version of the Global Initiative for Chronic Obstructive Lung Disease Staging.

Can blood eosinophil count be used as a predictive marker for the severity of COPD and concomitant cardiovascular disease? The relationship with the 2023 Version of the Global Initiative for Chronic Obstructive Lung Disease Staging.

Fuente:European Review For Medical and Pharmacological Sciences

Extracto: The results of our study indicate a strong relationship between eosinophils and cardiovascular events in COPD subjects, particularly in subjects at high risk of exacerbations and cardiovascular complications.

Cita:Eur Rev Med Pharmacol Sci 2024 Apr; 28 (7) : 2777-2787.

Autor/es:Bozkuş, F (a)
Samur, A (b)

institución:Bozkuş, F (a)
Samur, A (b)

Formato:Informe impreso

Idioma:Inglés

País de fuente:Italia

Sitio web:http://dx.doi.org/10.26355/eurrev_202404_35906

Is aortic knob width a novel predictor of mortality in hemodialysis patients?

Fuente:European Review For Medical and Pharmacological Sciences

Tipo de trabajo:Revisión

Extracto: Age, male gender, aortic calcification, and hypertension are the primary risk factors for increased aortic knob width in hemodialysis patients. Aortic knob width greater than 37.98 mm, which can be measured simply and rapidly using posterior-anterior chest radiography, may be a predictor of mortality. GRAPHICAL ABSTRACT: https://www.europeanreview.org/wp/wp-content/uploads/Graphical-Abstract-10.jpg.

Cita:Eur Rev Med Pharmacol Sci 2024 Apr; 28 (7) : 2805-2816.

Autor/es:Kaya, B (a)
Mete, B (b)

institución:Kaya, B (a)
Mete, B (b)

Formato:Informe impreso

Idioma:Inglés

País de fuente:Italia

Sitio web:http://dx.doi.org/10.26355/eurrev_202404_35909

Transit time flow measurement in off-pump surgery: is it a functional index of the biological graft integrity?

Fuente:European Review For Medical and Pharmacological Sciences

Extracto: Diabetic patients, especially in the insulin-dependent subgroups, have demonstrated lower MGF and higher PI values collected from venous anastomoses with, conversely, inverse results from the arterial one. These results might be correlated to an altered biological adaptability caused by the effects of the diabetic endocrine disorder.

Cita:Eur Rev Med Pharmacol Sci 2024 Apr; 28 (7) : 2848-2859.

Autor/es:Vinciguerra, M (a)
D'Abramo, M (b)

institución:Vinciguerra, M (a)
D'Abramo, M (b)

Formato:Informe impreso

Idioma:Inglés

País de fuente:Italia

Sitio web:http://dx.doi.org/10.26355/eurrev_202404_35914