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Discharge within 24 h, transvaginal natural orifice transluminal endoscopic surgery- more suitable for ambulatory surgery in gynecology procedures: a retrospective study.
Discharge within 24 h, transvaginal natural orifice transluminal endoscopic surgery- more suitable for ambulatory surgery in gynecology procedures: a retrospective study.
Fuente:Bmc Women's Health
Extracto:
These comprehensive
data reveal the capacity of vNOTES to increase surgical efficiency. vNOTES in
gynecological procedures may demonstrate sufficient feasibility and provide a new
medical strategy compared with laparo-endoscopic single-site surgery for
ambulatory surgery in gynecological procedures.
institución:(a) Department of Gynecology and Obstetrics, School of Medicine, Chengdu Women's and Children's Central Hospital, University of Electronic Science and Technology of China, 1617 Riyue Avenue, Chengdu, Sichuan, 610073, China. (b) The Second Affiliated Hospital of Chongqing Medical University, Chongqing, 400042, China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
institución:(a) Department of Obstetrics and Gynecology, The Second Hospital of Jilin University, Jilin University, Changchun 130041, China. (b) Engineering Research Center of Bioreactor and Pharmaceutical Development, Ministry of Education, College of Life Science, Jilin Agricultural University, No. 2888, Xincheng Street, Changchun 130118, China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
institución:(a) Faculty of Informatics, University of Debrecen, 4028 Debrecen, Hungary. (b) Faculty of Informatics, University of Debrecen, 4028 Debrecen, Hungary.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Trastuzumab deruxtecan in previously treated HER2-positive metastatic or unresectable breast cancer: Real-life data from the temporary use authorization program in France.
Trastuzumab deruxtecan in previously treated HER2-positive metastatic or unresectable breast cancer: Real-life data from the temporary use authorization program in France.
Fuente:Cancer Medicine
Extracto:
In this early access program in patients with heavily pretreated
HER2-positive metastatic/unresectable breast cancer, T-DXd had antitumor activity
with a similar response to that reported in previous clinical studies. T-DXd was
well tolerated and no new safety signals were observed.
Claves:HER2‐positive, breast cancer, early‐access program, metastatic cancer, trastuzumab deruxtecan
Cita:Cancer Med 2024 May; 13 (9) : e7168.
Autor/es:Petit, Thierry (a) Hajjaji, Nawale (b)
institución:(a) Département d'Oncologie Médicale, Centre Paul Strauss, Strasbourg, France. (b) Département de Cancérologie Sénologique, Centre Oscar Lambret, INSERM U1192, Laboratoire PRISM, Lille, France.
Conflicto:Nawale Hajjaji reports competing interests with Pfizer, Novartis, Lilly, Daiichi Sankyo, Gilead, AstraZeneca (consulting fees), Novartis, Pfizer (research grant to institution), and Daiichi Sankyo, AstraZeneca (travel expenses); Marc‐Antoine Benderra reports competing interest with Daiichi Sankyo support for attending meetings and/or travel; participation on a Data Safety Monitoring Board or Advisory Board; Cyril Foa reports competing interests with Roche, MSD, AstraZeneca,...
a, Novartis; Julien Grenier reports competing interest for Daiichi Sankyo (congress) and AstraZeneca/Daiichi Sankyo (board); Mahasti Saghatchian reports competing interests with AstraZeneca (consulting/expert, speaker/conferences, research grants/clinical trials), BMS (research grants/clinical trials), Daiichi Sankyo (consulting/expert, speaker/conferences, research grants/clinical trials, conference travel), Eisai (consulting/expert, speaker/conferences), Myriad Genetics (consulting/expert, speaker/conferences, research grants/clinical trials), Seagen (consulting/expert, speaker/conferences, research grants/clinical trials, conference travel), MSD (consulting/expert, research grants/clinical trials, conference travel), Novartis (consulting/expert, speaker/conferences, research grants/clinical trials, conference travel), Pfizer (consulting/expert, speaker/conferences, research grants/clinical trials, conference travel), Viatris (consulting/expert, speaker/conferences), Roche (consulting/expert, speaker/conferences, research grants/clinical trials, conference travel), Menarini‐Stemline (consulting/expert); Véronique Diéras reports competing interest with Roche, Novartis, Pfizer, Lilly, AstraZeneca, Daiichi Sankyo, Seagen, Gilead, MSD (travel expenses), Roche/Genentech, Novartis, Lilly, Pfizer, AstraZeneca, AbbVie, MSD, Daiichi Sankyo, Seagen, Gilead, Eisai, Pierre Fabre Oncologie, Medac GmbH, Menarini (honoraria for consulting), Roche, Novartis, Pfizer, Lilly, Astra Zeneca, Daiichi Sankyo, Seagen, Gilead (honoraria for symposia); Luis Teixeira reports competing interest with Roche, Novartis, AZD, Daiichi‐Sankyo (consulting or advisory role); Nadine Dohollou reports competing interests with AstraZeneca, BMS, Boehringer Ingelheim, Genomic Health, Lilly, MSD, Novartis, Pfizer, Roche (research grants for clinical trials), Daiichi, Lilly, Roche, Seagen (consulting/expert and conferences/trainings); Thomas Bachelot reports personal fees (Seagen), grants to institution (Seagen), personal fees (Pfizer), grants to institution (Pfizer), personal fees (AstraZeneca/Daiichi), grants to institution (AstraZeneca/Daiichi), personal fees (Novartis), grants to institution (Novartis), personal fees (Lilly), non‐financial support (Pfizer). The other authors did not report competing interests.
Long non-coding RNA NEAT1 promotes aerobic glycolysis and progression of cervical cancer through WNT/?-catenin/PDK1 axis.
Long non-coding RNA NEAT1 promotes aerobic glycolysis and progression of cervical cancer through WNT/?-catenin/PDK1 axis.
Fuente:Cancer Medicine
Extracto:
In summary, these findings indicated that NEAT1 may
contribute to the progression of cervical cancer by activating the
WNT/β-catenin/PDK1 signaling axis.
Gynecological endocrinology the official journal of the International Society of Gynecological Endocrinology
Selección SIIC: 16 Mayo, 2024
Gynecological endocrinology the official journal of the International Society of Gynecological Endocrinology
The impact of androgen levels on serum metabolic profiles in patients with polycystic ovary syndrome.
The impact of androgen levels on serum metabolic profiles in patients with polycystic ovary syndrome.
Fuente:Gynecological Endocrinology The Official Journal of The International Society of Gynecological Endocrinology
Extracto:
Elevated serum androgen levels are commonly observed in patients with
PCOS and are associated with multiple metabolic abnormalities. Therefore, it is
recommended to regularly monitor glucose and lipid metabolism-related indicators
in patients with PCOS who have elevated androgen levels.
institución:(a) Department of Gynecology, The First People's Hospital of Yunnan Province, Kunming, China. (b) The Affiliated Hospital of Kunming University of Science and Technology, Kunming, Yunnan, China.
Gynecological endocrinology the official journal of the International Society of Gynecological Endocrinology
Selección SIIC: 16 Mayo, 2024
Gynecological endocrinology the official journal of the International Society of Gynecological Endocrinology
Diagnostic value of ultrasound elastography in polycystic ovary syndrome
Diagnostic value of ultrasound elastography in polycystic ovary syndrome
Fuente:Gynecological Endocrinology The Official Journal of The International Society of Gynecological Endocrinology
Tipo de trabajo:Revisión sistemática
Extracto:
This systematic review and meta-analysis found that women with PCOS
had stiffer ovarian tissue than women without the disorder. Ultrasound
elastography may provide clinicians with value beyond 2D ultrasound in the
diagnosis of PCOS.
institución:(a) Department of Ultrasound, Sichuan University West China Second University Hospital, Chengdu, China. (b) Key Laboratory of Birth Defects and Related Diseases of Women and Children (Sichuan University), Ministry of Education, Chengdu, China.
Safety of immune checkpoint inhibitors in patients aged over 80 years
Safety of immune checkpoint inhibitors in patients aged over 80 years
Fuente:Cancer Immunology, Immunotherapy Cii
Tipo de trabajo:Estudio de cohortes
Extracto:
IO therapy is a safe
treatment option for patients > 80 years old. Furthermore, patients with elevated
eosinophil counts at treatment initiation should be cautiously managed.
institución:(a) Cancer Treatment Center, Kansai Medical University Hospital, 2-3-1, Shinmachi, Hirakata, Osaka-Prefecture, 573-1191, Japan. (b) Department of Thoracic Oncology, Kansai Medical University, 2-3-1, Shinmachi, Hirakata, Osaka-Prefecture, 573-1191, Japan.
Conflicto:TK received grants from MSD, Astra Zeneca, Amgen, Boehringer Ingelheim, Daiichi Sankyo pharmaceutical, Takeda pharmaceutical, and Bristol Meyers Squibb, and honoraria for lecture from Astra Zeneca, Ono pharmaceutical, MSD, Nippon Kayaku, Takeda pharmaceutical, Eli Lilly, Bristol Meyers Squibb, Chugai pharmaceutical, and Pizer.
International journal of hyperthermia the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group
Selección SIIC: 16 Mayo, 2024
International journal of hyperthermia the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group
Study on the safety and efficacy of HIFU in the treatment of VaIN.
Study on the safety and efficacy of HIFU in the treatment of VaIN.
Fuente:International Journal of Hyperthermia The Official Journal of European Society For Hyperthermic Oncology, North American Hyperthermia Group
Extracto:
HIFU is a safe and effective treatment for VaIN. However,
this study had a small sample size, a relatively short follow-up period, and
lacked a control group, requiring further investigation.
Claves:Vaginal intraepithelial neoplasia, efficacy, high-intensity focused ultrasound, human papillomavirus, safety
Cita:Int J Hyperthermia 2024; 41 (1) : 2346216.
Autor/es:Wu, Susu (a) Li, Xiang (b)
institución:(a) Department of Gynecology, Xiangya Third Hospital, Central South University, Changsha, Hunan, China. (b) Department of Gynecology, Xiangya Third Hospital, Central South University, Changsha, Hunan, China.
The journal of maternal-fetal & neonatal medicine the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians
Selección SIIC: 16 Mayo, 2024
The journal of maternal-fetal & neonatal medicine the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians
Risk factors analysis and multidisciplinary team first-aid simulation training for umbilical cord prolapse can improve neonatal outcomes.
Risk factors analysis and multidisciplinary team first-aid simulation training for umbilical cord prolapse can improve neonatal outcomes.
Fuente:The Journal of Maternal-fetal & Neonatal Medicine The Official Journal of The European Association of Perinatal Medicine, The Federation of Asia and Oceania Perinatal Societies, The International Society of Perinatal Obstetricians
Tipo de trabajo:Revisión
Extracto:
MDT first-aid simulation training for
overt UCP can improve neonatal outcomes. However, medical simulation training
efforts should initially focus on the early identification of risk factors for
both overt and occult UCP.
Claves:Umbilical cord prolapse, first aid simulation training, multidisciplinary team, neonatal outcomes, risk factors
institución:(a) Department of Obstetrics and Gynecology, The Third Affiliated Hospital, Sun Yat-sen University, Guangzhou, China. (b) Department of Obstetrics and Gynecology, The Third Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.
Medical Students' General Beliefs and Specific Perceptions about Patient Feedback Before and after Training in a Clinical Context.
Medical Students' General Beliefs and Specific Perceptions about Patient Feedback Before and after Training in a Clinical Context.
Fuente:Perspectives On Medical Education
Extracto:
We suggest implementing longitudinal feedback training in
medical curricula, where students are guided and supported in the complex task of
learning from patients through feedback.
Cita:Perspect Med Educ 2024; 13 (1) : 288-299.
Autor/es:Eijkelboom, M Charlotte L (a) de Kleijn, Renske A M (b)
institución:(a) Utrecht University, the Netherlands. (b) Department of Pediatrics, University Medical Center Utrecht, the Netherlands.
Conflicto:The authors have no competing interests to declare.
The Median Effective Dose of Intrathecal Hyperbaric Bupivacaine for Cesarean Section at Moderately High-Altitude.
The Median Effective Dose of Intrathecal Hyperbaric Bupivacaine for Cesarean Section at Moderately High-Altitude.
Fuente:Drug Design, Development and Therapy
Tipo de trabajo:Orientaciones y guía
Extracto:
The
ED(50) dose of 0.75% hyperbaric bupivacaine for spinal anesthesia during cesarean
section at moderately high altitude is 8.23 mg, which exceeds the ED(50) dose
typically required by parturients at low altitude. Comprehensive investigations
are warranted to ascertain the ED(90) or ED(95) dose of local anesthetics for
cesarean section at moderately high altitudes, thereby offering enhanced guidance
for clinical practice.
Claves:ED50 dose, bupivacaine, high altitude, spinal anesthesia
Cita:Drug Des Devel Ther 2024; 18 : 1313-1319.
Autor/es:Yang, Chen (a) Dong, Wangjun (b)
institución:(a) Department of Anesthesia, Obstetrics & Gynecology Hospital, Fudan University, Shanghai, People's Republic of China. (b) Department of Anesthesia, Yongping County People's Hospital, Yunnan, People's Republic of China.
Conflicto:The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
Glucagon kinetics assessed by mathematical modelling during oral glucose administration in people spanning from normal glucose tolerance to type 2 diabetes.
Glucagon kinetics assessed by mathematical modelling during oral glucose administration in people spanning from normal glucose tolerance to type 2 diabetes.
Fuente:Frontiers in Endocrinology
Extracto:
The alpha-cell
insulin sensitivity is highly variable among subjects, and it is different in
groups at different glucose tolerance. This may be relevant for defining
personalized treatment schemes, in terms of dietary prescriptions but also for
treatments with glucagon-related agents.
Autor/es:Andreozzi, Francesco (a) Mancuso, Elettra (b)
institución:(a) Department of Medical and Surgical Sciences, Magna Graecia University of Catanzaro, Catanzaro, Italy. (b) Department of Medical and Surgical Sciences, Magna Graecia University of Catanzaro, Catanzaro, Italy.
Conflicto:The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
Postpartum Emergency Department Use Following Midwifery-Model vs Obstetrics-Model Care.
Postpartum Emergency Department Use Following Midwifery-Model vs Obstetrics-Model Care.
Fuente:Jama Network Open
Tipo de trabajo:Estudio de cohortes
Extracto:
AND RELEVANCE: In this cohort
study, midwifery-model care was associated with less postpartum ED use than
traditional obstetrics-model care among women who had low risk and were
primiparous, which may be due to early access to postpartum care provided by
Ontario midwives.
Cita:JAMA Netw Open 2024 Apr 1; 7 (4) : e248676.
Autor/es:Sorbara, Carla (a) Ray, Joel G (b)
institución:(a) Department of Obstetrics and Gynecology, North York General Hospital, Toronto, Ontario, Canada. (b) ICES, Toronto, Ontario, Canada.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Factors associated with interobserver variation amongst pathologists in the diagnosis of endometrial hyperplasia
Factors associated with interobserver variation amongst pathologists in the diagnosis of endometrial hyperplasia
Fuente:Plos One
Tipo de trabajo:Revisión sistemática
Extracto:
This review
highlighted the impact of pathologist-specific factors and working practices in
the accurate diagnosis of EH, although few studies have been conducted. Further
research is warranted in the development of more objective criteria that could
improve reproducibility in EH diagnostic reporting, as well as determining the
applicability of novel methods such as grading the degree of nuclear atypia in
clinical settings.
Cita:PLoS One 2024; 19 (4) : e0302252.
Autor/es:McCoy, Chloe A (a) Coleman, Helen G (b)
institución:(a) Centre for Public Health, Queen's University Belfast, Belfast, Northern Ireland, United Kingdom. (b) Centre for Public Health, Queen's University Belfast, Belfast, Northern Ireland, United Kingdom.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Maternal care utilization and provision during the COVID-19 pandemic: Voices from minoritized pregnant and postpartum women and maternal care providers in Deep South.
Maternal care utilization and provision during the COVID-19 pandemic: Voices from minoritized pregnant and postpartum women and maternal care providers in Deep South.
Fuente:Plos One
Extracto:
The pandemic has disrupted maternal care
services. To overcome these issues, health facilities should integrate community
resources, adopt telehealth, and develop culturally tailored education programs
for pregnant and postpartum women. Supporting MCPs with resources will enhance
the quality of care and address health disparities in African American and
Hispanic women.
Cita:PLoS One 2024; 19 (4) : e0300424.
Autor/es:Zhang, Ran (a) Byrd, Tiffany (b)
institución:(a) Department of Health Promotion, Education and Behavior, Arnold School of Public Health, University of South Carolina, Columbia, South Carolina, United States of America. (b) Department of Health Promotion, Education and Behavior, Arnold School of Public Health, University of South Carolina, Columbia, South Carolina, United States of America.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Maternal positional therapy for fetal growth and customised birth weight centile benefit in a Bayesian reanalysis of a double-blind, sham-controlled, randomised clinical trial.
Maternal positional therapy for fetal growth and customised birth weight centile benefit in a Bayesian reanalysis of a double-blind, sham-controlled, randomised clinical trial.
Fuente:Bmj Open
Tipo de trabajo:Estudio clínico
Extracto:
Maternal nightly PT throughout the third-trimester did
not have a statistically significant effect on CBWC on a frequentist analysis
using the latest fetal growth standard. However, from a Bayesian analysis,
clinicians can infer that PT is likely to benefit fetal growth but with a modest
effect size. TRIAL REGISTRATION NUMBER: NCT02379728.
Claves:Fetal medicine, Maternal medicine, SLEEP MEDICINE, STATISTICS & RESEARCH METHODS
Cita:BMJ Open 2024 Apr 28; 14 (4) : e078315.
Autor/es:Coleman, Jerry (a) Grewal, Sahibjot (b)
institución:(a) Obstetrics & Gynaecology, Korle Bu Teaching Hospital, Accra, Greater Accra, Ghana. (b) University of Toronto Faculty of Medicine, Toronto, Ontario, Canada.
Conflicto:Competing interests: All authors have completed the ICMJE uniform disclosure form at https://www.icmje.org/disclosure-of-interest/ and declare: Dr Kember is the President, CEO and majority shareholder of Shiphrah Biomedical (SBI), which is a research-based medical device company specialising in sleep during pregnancy. Dr Kember receives no financial or material benefit for his roles at SBI. Dr Kember is listed as an inventor...
on a patent-pending positional therapy device for use during sleep in pregnancy. Dr Warland is listed as an inventor on a patent-pending positional therapy device for use during sleep in pregnancy. The other authors—Dr Coleman, Mr Grewal, Dr Hobson and Dr Liu—have declared no support from any organisation for the submitted work, no financial relationships with any organisations that might have an interest in the submitted work in the previous 3 years and no other relationships or activities that could appear to have influenced the submitted work.
Maternity healthcare professionals' experiences of supporting women in decision-making for labour and birth: a qualitative study.
Maternity healthcare professionals' experiences of supporting women in decision-making for labour and birth: a qualitative study.
Fuente:Bmj Open
Extracto:
We found that MHCPs are committed to SDM but need better support to
deliver it. Structured processes including Core Information Sets, communication
skills training and decision support aids may help to consistently deliver SDM in
maternity care.
Claves:Clinical Decision-Making, Decision Making, OBSTETRICS, QUALITATIVE RESEARCH
Cita:BMJ Open 2024 Apr 28; 14 (4) : e080961.
Autor/es:Hardman, Kitty (a) Davies, Anna (b)
institución:(a) Centre for Academic Women's Health, University of Bristol, Bristol, UK. (b) North Bristol NHS Trust, Westbury on Trym, UK.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Effects of maternal exercise on infant mesenchymal stem cell mitochondrial function, insulin action, and body composition in infancy.
Effects of maternal exercise on infant mesenchymal stem cell mitochondrial function, insulin action, and body composition in infancy.
Fuente:Physiological Reports
Extracto:
These
data suggest that infants from exercising mothers are relatively leaner, and this
is associated with higher infant MSC mitochondrial respiration, fat use, and
insulin action.
institución:(a) Department of Kinesiology, East Carolina University, Greenville, North Carolina, USA. (b) Human Performance Laboratory, East Carolina University, Greenville, North Carolina, USA.
Gestational diabetes-related gut microbiome dysbiosis is not influenced by different Asian ethnicities and dietary interventions: a pilot study.
Gestational diabetes-related gut microbiome dysbiosis is not influenced by different Asian ethnicities and dietary interventions: a pilot study.
Fuente:Scientific Reports
Extracto:
Women with GDM have a distinct gut microbiome
profile which harbours common features across different Asian ethnic groups,
consistent with the notion that specific microbes are involved in the
pathogenesis of insulin resistance, pro-inflammatory conditions, and other
metabolic dysregulation known to be present in GDM.
Cita:Sci Rep 2024 Apr 29; 14 (1) : 9855.
Autor/es:Gupta, Abhishek (a) Chan, Shiao Yng (b)
institución:(a) Singapore Centre For Environmental Life Sciences Engineering (SCELSE), National University of Singapore, Singapore, Singapore. a_gupta7@nus.edu.sg. (b) Department of Obstetrics and Gynaecology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación