Health System and Individual Barriers to Supporting Healthy Gestational Weight Gain and Nutrition: A Qualitative Study of the Experiences of Midwives and Obstetricians in Publicly Funded Antenatal Care in Tasmania, Australia.

Health System and Individual Barriers to Supporting Healthy Gestational Weight Gain and Nutrition: A Qualitative Study of the Experiences of Midwives and Obstetricians in Publicly Funded Antenatal Care in Tasmania, Australia.

Fuente:Nutrients

Extracto: Improving access to continuity of care and clinician training, and providing resources that appropriately consider women's socioeconomic circumstances and health literacy would enhance the ability and opportunities for clinicians to better support all women.

Claves:antenatal care, behaviour change, nutrition/diet, physical activity, pregnancy, weight/obesity

Cita:Nutrients 2024 Apr 23; 16 (9)

Autor/es:Kilpatrick, Michelle L (a)
Venn, Alison J (b)

institución:(a) Menzies Institute for Medical Research, College of Health and Medicine, University of Tasmania, Hobart, TAS 7000, Australia.
(b) Centre for Mental Health Service Innovation, Advocate House, Hobart, TAS 7000, Australia.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3390/nu16091251

Blood Lead Level as Marker of Increased Risk of Ovarian Cancer in BRCA1 Carriers.

Fuente:Nutrients

Extracto: Validation in diverse populations and exploration of detoxification methods for lowering lead levels are required.

Claves:BRCA1, cancer, microelements, ovarian cancer

Cita:Nutrients 2024 Apr 30; 16 (9)

Autor/es:Kiljańczyk, Adam (a)
Matuszczak, Milena (b)

institución:(a) Department of Genetics and Pathology, International Hereditary Cancer Center, Pomeranian Medical University, ul. Unii Lubelskiej 1, 71-252 Szczecin, Poland.
(b) Department of Genetics and Pathology, International Hereditary Cancer Center, Pomeranian Medical University, ul. Unii Lubelskiej 1, 71-252 Szczecin, Poland.

Conflicto:Author J.L., W.M., R.D., P.B., J.G., C.C., and T.H. were employed by the company Read-Gene SA, Grzepnica, ul. Alabastrowa 8, 72-003 Dobra, Poland. The remaining authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3390/nu16091370

Vitamins in Gynecologic Malignancies.

Fuente:Nutrients

Extracto: It has been observed that there is a U-shaped relationship between group B vitamins and metabolic markers and clinical outcomes.

Claves:4-HPR, FITC, FR-α, TAC-101, VDR, all-trans retinoic acid, calcitriol, retinoic acid

Cita:Nutrients 2024 May 5; 16 (9)

Autor/es:Wierzbowska, Natalia (a)
Olszowski, Tomasz (b)

institución:(a) Department of Reconstructive Surgery and Gynecological Oncology, Pomeranian Medical University in Szczecin, Al. Powstańców Wielkopolskich 72, 70-111 Szczecin, Poland.
(b) Department of Hygiene and Epidemiology, Pomeranian Medical University in Szczecin, Al. Powstańców Wielkopolskich 72, 70-111 Szczecin, Poland.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3390/nu16091392

Maternal serum alpha-1 antitrypsin levels in spontaneous preterm and term pregnancies.

Maternal serum alpha-1 antitrypsin levels in spontaneous preterm and term pregnancies.

Fuente:Scientific Reports

Extracto: We propose that during early pregnancy, complicated by subsequent SPTB, modest elevation of serum AAT associates with SPTB.

Cita:Sci Rep 2024 May 11; 14 (1) : 10819.

Autor/es:Tissarinen, Pinja (a)
Tiensuu, Heli (b)

institución:(a) Research Unit of Clinical Medicine and Medical Research Center, Department of Pediatrics and Adolescent Medicine, Oulu University Hospital, University of Oulu, PO Box 5000, 90014, Oulu, Finland.
(b) Research Unit of Clinical Medicine and Medical Research Center, Department of Pediatrics and Adolescent Medicine, Oulu University Hospital, University of Oulu, PO Box 5000, 90014, Oulu, Finland.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1038/s41598-024-61206-z

Vaccination in twin pregnancies: comparison between immunization before conception and during pregnancy.

Fuente:Scientific Reports

Extracto: https://clinicaltrials.gov/ ID: NCT04595214.

Claves:BNT162b2 Pfizer/BioNTech vaccination, COV-2-Trimeric S-IgG -b1, Neutralizing antibodies, PCR, SARS-CoV-2, Twin pregnancy

Cita:Sci Rep 2024 May 11; 14 (1) : 10813.

Autor/es:Svirsky, Ran (a)
Rabbi, Moran Landau (b)

institución:(a) Department of Obstetrics and Gynecology, Shamir (Assaf Harofeh) Medical Center, Zerifin, Israel. rsvirs@gmail.com.
(b) Medical Genetic Unit, Department of Obstetrics and Gynecology, Samson Assuta Ashdod University Hospital, Ashdod, Israel. rsvirs@gmail.com.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1038/s41598-024-61504-6

Multi-omics integration highlights the role of ubiquitination in endometriosis fibrosis.

Multi-omics integration highlights the role of ubiquitination in endometriosis fibrosis.

Fuente:Journal of Translational Medicine

Extracto: This study, employing multi-omics approaches, provides novel insights into endometriosis ubiquitination profiles and reveals aberrant expression of the E3 ubiquitin ligase TRIM33 in endometriotic tissues, emphasizing their critical involvement in fibrosis pathogenesis and potential therapeutic targets.

Claves:Endometriosis, Fibrosis, Proteomics, TRIM33, Ubiquitylomics

Cita:J Transl Med 2024 May 12; 22 (1) : 445.

Autor/es:Yang, Mengjie (a)
Jiang, Hong (b)

institución:(a) Clinical Medical Research Center for Gynecological Reproductive Health of Fujian Province, Laboratory of Research and Diagnosis of Gynecological Diseases of Xiamen City, Department of Obstetrics and Gynecology, the First Affliated Hospital of Xiamen University, School of Medicine, Xiamen University, Xiamen, China.
(b) National Institute for Data Science in Health and Medicine, Xiamen University, Xiamen, China.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1186/s12967-024-05245-0

Unlocking the complete blood count as a risk stratification tool for breast cancer using machine learning: a large scale retrospective study.

Unlocking the complete blood count as a risk stratification tool for breast cancer using machine learning: a large scale retrospective study.

Fuente:Scientific Reports

Extracto: As a risk stratification tool, this model offers the potential for personalized breast cancer screening by prioritizing women based on their individual risk, thereby indicating a shift from a broad population strategy.

Claves:Breast cancer, CBC, CBC-ratios, Hemogram, Machine learning, NLR, RBC, Risk stratification, Routine blood tests, Screening

Cita:Sci Rep 2024 May 12; 14 (1) : 10841.

Autor/es:Araujo, Daniella Castro (a)
Rocha, Bruno Aragão (b)

institución:(a) Huna, São Paulo, Brazil. danicastroaraujo@gmail.com.
(b) Departamento de Ciências da Computação, Instituto de Ciências Exatas, Universidade Federal de Minas Gerais/UFMG, Campus Belo Horizonte, Minas Gerais, Brazil. danicastroaraujo@gmail.com.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1038/s41598-024-61215-y

Prognostic implications of STK11 with different mutation status and its relationship with tumor-infiltrating immune cells in non-small cell lung cancer.

Prognostic implications of STK11 with different mutation status and its relationship with tumor-infiltrating immune cells in non-small cell lung cancer.

Fuente:Frontiers in Immunology

Extracto: Low STK11 expression at protein level and presence of STK11 mutation were associated with poor prognosis in NSCLC, and mutated STK11 might probably alter the expression IRGs profiling.

Claves:STK11 gene, immune related genes, immunochemistry, non-small cell lung cancer, prognostic analysis

Cita:Front Immunol 2024; 15 : 1387896.

Autor/es:Zheng, Jianqing (a)
Deng, Yujie (b)

institución:(a) Department of Radiation Oncology, The Second Affiliated Hospital of Fujian Medical University, Quanzhou, Fujian, China.
(b) Department of Medical Oncology, The First Affiliated Hospital of Fujian Medical University, Fuzhou, Fujian, China.

Conflicto:The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3389/fimmu.2024.1387896

[Retrospective study of 60 cases of uterine rupture at the Maternity Center of Monastir, Tunisia].

[Retrospective study of 60 cases of uterine rupture at the Maternity Center of Monastir, Tunisia].

Fuente:The Pan African Medical Journal

Extracto: Patients with scarred uterus have a better prognosis.

Claves:Uterine rupture, dehiscence, prognosis, scarred uterus, unscarred uterus

Cita:Pan Afr Med J 2024; 47 : 83.

Autor/es:Farhat, Imen Ben (a)
Zoukar, Olfa (b)

institución:(a) Université de Monastir, Faculté de Médecine de Monastir, Monastir, Tunisie.
(b) Service de Gynécologie Obstétrique du Centre de Maternité et de Néonatologie de Monastir, Monastir, Tunisie.

Conflicto:Les auteurs ne déclarent aucun conflit d'intérêts.

Formato:Informe virtual

Idioma:fre

País de fuente:Uganda

Sitio web:http://dx.doi.org/10.11604/pamj.2024.47.83.42188

Oxidative stress contributes to hypermethylation of Histone H3 lysine 9 in placental trophoblasts from preeclamptic pregnancies.

Oxidative stress contributes to hypermethylation of Histone H3 lysine 9 in placental trophoblasts from preeclamptic pregnancies.

Fuente:Frontiers in Endocrinology

Extracto: These findings are noteworthy and provide further evidence that increased oxidative stress in the intrauterine environment is likely a mechanism to induce aberrant histone modification in placental trophoblasts in preeclampsia. Moreover, CuZn-SOD and Mn-SOD expression/activity are possibly H3K9 methylation-dependent in placental trophoblasts, which further suggest that oxidative stress and aberrant histone modification have significant impact on placental trophoblasts/fetal programming in preeclampsia.

Claves:H3K9 methylation, hypoxia, oxidative stress, placental trophoblast, preeclampsia, superoxide dismutase

Cita:Front Endocrinol (Lausanne) 2024; 15 : 1371220.

Autor/es:Gu, Yang (a)
Cooper, Danielle (b)

institución:(a) Department of Obstetrics and Gynecology, Louisiana State University Health Sciences Center, Shreveport, LA, United States.
(b) Department of Obstetrics and Gynecology, Louisiana State University Health Sciences Center, Shreveport, LA, United States.

Conflicto:The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. The author(s) declared that they were an editorial board member of Frontiers, at the time of submission. This had no impact on the peer review process and the final decision.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3389/fendo.2024.1371220

Outcomes associated with planned place of birth among low-risk pregnancies in Ontario, Canada (2012-2021)

Outcomes associated with planned place of birth among low-risk pregnancies in Ontario, Canada (2012-2021)

Fuente:Plos One

Tipo de trabajo:Estudio de cohortes

Extracto: To reduce the impact of selection bias in estimating the effect of planned place of birth on neonatal and maternal outcomes, we will use propensity score (PS) overlap weighting (OW) and modified Poisson regression to conduct multivariate analyses.

Cita:PLoS One 2024; 19 (5) : e0302489.

Autor/es:Darling, Elizabeth K (a)
Hébert, Vanessa (b)

institución:(a) McMaster Midwifery Research Centre, McMaster University, Hamilton, Ontario, Canada.
(b) Department of Obstetrics and Gynecology, McMaster University, Hamilton, Ontario, Canada.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:EE.UU.

Sitio web:http://dx.doi.org/10.1371/journal.pone.0302489

The prevalence of internalized stigma and its association with HIV viral suppression among fully disclosed adolescents and young adults living with HIV (AYLHIV) receiving HIV care in an HIV clinic in Plateau State, Nigeria.

Fuente:Plos One

Extracto: However, the study reported no statistically significant association between internalized stigma domains and viral suppression.

Cita:PLoS One 2024; 19 (5) : e0303360.

Autor/es:Osayi, Emmanuel O (a)
Ajayi, Oluseye (b)

institución:(a) Directorate of Clinical Services, APIN Public Health Initiatives Jos, Plateau, Nigeria.
(b) Directorate of Prevention, APIN Public Health Initiatives FCT-Abuja, Abuja, Nigeria.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:EE.UU.

Sitio web:http://dx.doi.org/10.1371/journal.pone.0303360

Determinants of severe maternal outcome in Keren hospital, Eritrea: An unmatched case-control study.

Fuente:Plos One

Extracto: In this study, lack of ANC follow up, caesarean section in the current pregnancy, referral from lower facilities, distance from nearest health facility, history of anaemia and previous caesarean section were associated with SMO. Thus, improved transportation facilities, robust referral protocol and equitable distribution of emergency facilities can play vital role in reducing SMO in the hospital.

Cita:PLoS One 2024; 19 (5) : e0299663.

Autor/es:In this study, lack of ANC follow up, caesarean section in the current pregnancy, referral from lower facilities, distance from nearest health facility, history of anaemia and previous caesarean section were associated with SMO. Thus, improved transportation facilities, robust referral protocol and equitable distribution of emergency facilities can play vital role in reducing SMO in the hospital.

institución:In this study, lack of ANC follow up, caesarean section in the current pregnancy, referral from lower facilities, distance from nearest health facility, history of anaemia and previous caesarean section were associated with SMO. Thus, improved transportation facilities, robust referral protocol and equitable distribution of emergency facilities can play vital role in reducing SMO in the hospital.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:EE.UU.

Sitio web:http://dx.doi.org/10.1371/journal.pone.0299663

Nutritional status of primary school children and their caregiver's knowledge on malnutrition in rural and urban communities of Ekiti State, Southwest Nigeria.

Fuente:Plos One

Extracto: Generally, the prevalence of malnutrition was high in both urban and rural primary school children in this study. However, while underweight and stunting were more prevalent among the children in the rural communities, wasting, overweight and obesity were more prevalent in the urban. The caregivers in both communities had good knowledge of malnutrition (better in the urban) but this is not good enough to bring a significant relationship with the occurrence of malnutrition in the children. Common predictors of malnutrition in both community settings are being in lower primary school class, relationship with caregiver, educational status of caregiver and occupation of caregiver. It is therefore recommended that regular continuous public enlightenment, nutritional education programmes and other programmes targeted at improving the economic power of the caregivers are measures that will improve the nutritional status of the primary school children.

Cita:PLoS One 2024; 19 (5) : e0303492.

Autor/es:Sanni, Taofeek Adedayo (a)
Elegbede, Olusegun Elijah (b)

institución:(a) Department of Community Medicine, Federal Teaching Hospital, Ido-Ekiti, Ekiti State, Nigeria.
(b) Department of Community Medicine, Afe Babalola University, Ado-Ekiti, Ekiti State, Nigeria.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:EE.UU.

Sitio web:http://dx.doi.org/10.1371/journal.pone.0303492

The Immune Response of OAS1, IRF9, and IFI6 Genes in the Pathogenesis of COVID-19.

The Immune Response of OAS1, IRF9, and IFI6 Genes in the Pathogenesis of COVID-19.

Fuente:International Journal of Molecular Sciences

Extracto: In conclusion, the relevance of OAS1, IRF9, and IFI6 in controlling the viral infection was confirmed.

Claves:COVID-19, SARS-CoV-2, antiviral genes, gene expression, immune response

Cita:Int J Mol Sci 2024 Apr 24; 25 (9)

Autor/es:Gajate-Arenas, Malena (a)
Fricke-Galindo, Ingrid (b)

institución:(a) Instituto Universitario de Enfermedades Tropicales y Salud Pública de Canarias (IUETSPC), Universidad de La Laguna, 38029 San Cristóbal de La Laguna, Spain.
(b) HLA Laboratory, Instituto Nacional de Enfermedades Respiratorias Ismael Cosío Villegas, Mexico City 14080, Mexico.

Conflicto:The authors declare that this research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflicts of interest.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3390/ijms25094632

A mixed-methods study to investigate feasibility and acceptability of an early warning score for preterm infants in neonatal units in Kenya: results of the NEWS-K study Neonatal early warning scores in Kenya.

A mixed-methods study to investigate feasibility and acceptability of an early warning score for preterm infants in neonatal units in Kenya: results of the NEWS-K study Neonatal early warning scores in Kenya.

Fuente:Bmc Pediatrics

Extracto: Newborn unit infant to staff ratios varied between 10 and 53 staff per 1 infant, depending upon time of shift and staff type. A randomised trial of neonatal EWS in Kenya is possible and acceptable, though adaptations are required to the form before implementation.

Claves:Early warning score, Neonatal, Newborn unit

Cita:BMC Pediatr 2024 May 11; 24 (1) : 326.

Autor/es:Mitchell, Eleanor J (a)
Aluvaala, Jalemba (b)

institución:(a) Nottingham Clinical Trials Unit, School of Medicine, University of Nottingham, Nottingham, UK. Eleanor.mitchell@nottingham.ac.uk.
(b) Department of Paediatrics, University of Nairobi, Nairobi, Kenya.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1186/s12887-024-04778-z

Sexual behaviour among women using intramuscular depot medroxyprogesterone acetate, a copper intrauterine device, or a levonorgestrel implant for contraception: Data from the ECHO randomized trial.

Sexual behaviour among women using intramuscular depot medroxyprogesterone acetate, a copper intrauterine device, or a levonorgestrel implant for contraception: Data from the ECHO randomized trial.

Fuente:Plos One

Extracto: These findings suggest that women assigned to DMPA-IM may have a modest decrease in libido and sexual activity relative to the implant, and the implant relative to the Cu-IUD. We found more menstrual disturbance with DMPA-IM than with the implant (and as expected, both more than the Cu-IUD). These findings are important for informing the contraceptive choices of women and policymakers and highlight the need for robust comparison of the effects of other contraceptive methods as well.

Cita:PLoS One 2024; 19 (5) : e0299802.

Autor/es:Hofmeyr, G Justus (a)
Singata-Madliki, Mandisa (b)

institución:(a) University of Botswana, Gaborone, Botswana.
(b) Effective Care Research Unit, University of the Witwatersrand/Walter Sisulu University, East London, South Africa.

Conflicto:GJH has an interest in a blood loss monitoring device which is unrelated to this paper. JMB is an employee of Gilead Sciences, outside of the present work. JD joined Pfizer after the study was completed; and was previously with FHI 360. MSM, JB, PS, KKT, RI, IB, EM, CM, JD, JS, NP, TPP, KR, MO and TDM declare no... conflict of interest. There are no patents, products in development or marketed products associated with this research to declare.

Formato:Informe virtual

Idioma:Inglés

País de fuente:EE.UU.

Sitio web:http://dx.doi.org/10.1371/journal.pone.0299802

Proportions and determinants of successful surgical repair of obstetric fistula in low- and middle-income countries

Fuente:Plos One

Tipo de trabajo:Revisión sistemática

Extracto: The proportion of successful surgical repairs of obstetric fistula in low and middle-income countries remains suboptimal. Hence, stakeholders and policymakers must design and implement policies promoting women's education. In addition, fistula care providers need to reach and manage obstetric fistula cases early before complications, like vaginal fibrosis, occur.

Cita:PLoS One 2024; 19 (5) : e0303020.

Autor/es:Zeleke, Liknaw Bewket (a)
Welsh, Alec (b)

institución:(a) College of Health Sciences, Debre Markos University, Debre Markos, Ethiopia.
(b) Faculty of Medicine, School of Women's and Children's Health, University of New South Wales Sydney, Kensington, Australia.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:EE.UU.

Sitio web:http://dx.doi.org/10.1371/journal.pone.0303020

FEMaLe: The use of machine learning for early diagnosis of endometriosis based on patient self-reported data-Study protocol of a multicenter trial.

Fuente:Plos One

Extracto: We aim to develop a phenotypic description of women with endometriosis by linking the collected data with existing registry-based information on endometriosis diagnosis, healthcare utilization, and big data approach. This may help to achieve earlier detection of endometriosis with pelvic pain and significantly reduce the current diagnostic delay. Additionally, we may identify dietary components that worsen the quality of life and pain in women with endometriosis, upon which we can create real-world data-based nutritional recommendations.

Cita:PLoS One 2024; 19 (5) : e0300186.

Autor/es:Balogh, Dora B (a)
Hudelist, Gernot (b)

institución:(a) Department of Obstetrics and Gynecology, Semmelweis University, Budapest, Hungary.
(b) Department of Gynecology, Center for Endometriosis, Hospital St. John of God, Vienna, Austria.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:EE.UU.

Sitio web:http://dx.doi.org/10.1371/journal.pone.0300186

Prevalence and contributing factors of anemia in patients with gynecological cancer

Prevalence and contributing factors of anemia in patients with gynecological cancer

Fuente:Scientific Reports

Tipo de trabajo:Estudio de cohortes

Extracto: Further studies are needed to explore the long-term effects of these factors on patient outcomes and to develop targeted interventions.

Claves:Anemia, Gynecological Cancer, Hemoglobin Levels, Prevalence, Retrospective Cohort, Risk Factors

Cita:Sci Rep 2024 May 9; 14 (1) : 10628.

Autor/es:Ning, Kexue (a)
Sun, Xingyu (b)

institución:(a) College of Agroforestry and Health, The Open University of Sichuan, Chengdu, China.
(b) Department of Gynecology, The Affiliated Traditional Chinese Medicine Hospital, Southwest Medical University, Luzhou, 646000, Sichuan, China.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1038/s41598-024-61015-4