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Small peptide CSF fingerprint of amyotrophic lateral sclerosis.
Small peptide CSF fingerprint of amyotrophic lateral sclerosis.
Fuente:Plos One
Extracto:
No associations of disease
severity, duration and region of onset with sequenced peptides were found.
Cita:PLoS One 2024; 19 (4) : e0302280.
Autor/es:Lumi, Rea (a) Petri, Susanne (b)
institución:(a) Department of Neurology, Hannover University Medical School, Hannover, Germany. (b) Department of Neurology, Hannover University Medical School, Hannover, Germany.
Conflicto:S. Petri received honoraria as speaker/consultant from Biogen GmbH, Roche, Novartis, Teva, Cytokinetics Inc., Desitin, Italfarmaco, Ferrer, Amylyx, and Zambon; and grants from DGM e.V, Federal Ministry of Education and Research, German Israeli Foundation for Scientific Research and Development, EU Joint Program for Neurodegenerative Disease Research. J. Beige received funding from GSK and German Federal Ministries of Research and Health....
This does not alter our adherence to PLOS ONE policies on sharing data and materials.
Extracto:
By providing detailed clinical data and a diagnostic and treatment
approach, we aimed to improve the clinical understanding of femoral neck
fractures caused by TIO.
Claves:femoral neck fracture, hypophosphoruria, phosphaturic mesenchymal tumor, thoracic spine, total hip arthroplasty, tumor-induced osteomalacia
institución:(a) Department of Joint Surgery, The Affiliated Hospital of Qingdao University, Shandong, China. (b) Department of Joint Surgery, The Affiliated Hospital of Qingdao University, Shandong, China.
Conflicto:The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
Age- and sex-related changes in vertebral trabecular bone architecture in Neolithic and Mediaeval populations from Poland.
Age- and sex-related changes in vertebral trabecular bone architecture in Neolithic and Mediaeval populations from Poland.
Fuente:Scientific Reports
Extracto:
These data are found to be compatible with data from the
current biomedical literature, while no loss of horizontal trabeculae was
recorded as would be expected based on modern osteoporosis.
Autor/es:Galassi, Francesco Maria (a) Lorkiewicz, Wiesław (b)
institución:(a) Department of Anthropology, Faculty of Biology and Environmental Protection, University of Lodz, Lodz, Poland. francesco.galassi@biol.uni.lodz.pl. (b) Department of Anthropology, Faculty of Biology and Environmental Protection, University of Lodz, Lodz, Poland.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Causal roles of educational duration in bone mineral density and risk factors for osteoporosis: a Mendelian randomization study.
Causal roles of educational duration in bone mineral density and risk factors for osteoporosis: a Mendelian randomization study.
Fuente:Bmc Musculoskeletal Disorders
Extracto:
A longer educational duration was
causally linked with increased BMD. No causal relationship had been found between
educational duration and lean mass, time for light-to-moderate PA, milk intake,
and alcohol consumption as risk factors for osteoporosis.
Claves:Bone mineral density, Educational duration, Mendelian randomization, Osteoporosis, Risk factors
Cita:BMC Musculoskelet Disord 2024 May 2; 25 (1) : 345.
Autor/es:Qin, Yujun (a) Yang, Xia (b)
institución:(a) Department of General Practice, The First Affiliated Hospital of Guangxi Medical University, Guangxi Zhuang Autonomous Region, Nanning, P.R. China. 202200066@sr.gxmu.edu.cn. (b) The People's Hospital of Hechi, Guangxi Zhuang Autonomous Region, Hechi, P.R. China. 202200066@sr.gxmu.edu.cn.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Guidelines for fracture risk assessment and management of osteoporosis in postmenopausal women and men above the age of 50 in Qatar.
Guidelines for fracture risk assessment and management of osteoporosis in postmenopausal women and men above the age of 50 in Qatar.
Fuente:Archives of Osteoporosis
Tipo de trabajo:Revisión
Extracto:
Guidance is provided to all physicians across the country who are
involved in the care of patients with osteoporosis and fragility fractures.
institución:(a) Rheumatology Section, Department of Medicine, Hamad Medical Corporation, Doha, Qatar. Fiaz.alam@yahoo.com. (b) Rheumatology Section, Department of Medicine, Hamad Medical Corporation, Doha, Qatar.
Bone mineral density as an individual prognostic biomarker in NSCLC patients treated with immune checkpoint inhibitors.
Bone mineral density as an individual prognostic biomarker in NSCLC patients treated with immune checkpoint inhibitors.
Fuente:Frontiers in Immunology
Extracto:
Lower baseline BMD is associated with worse
clinical outcomes in NSCLC patients treated with ICIs. As a reliable and easily
obtained individual prognostic biomarker, BMD can become a routine detection
indicator before immunotherapy.
institución:(a) Department of Ultrasound Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China. (b) Hubei Key Laboratory of Molecular Imaging, Wuhan, China.
Conflicto:The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
Association of two geriatric treatment systems with anti-osteoporotic drug treatment and second hip fracture in patients with an index hip fracture
Association of two geriatric treatment systems with anti-osteoporotic drug treatment and second hip fracture in patients with an index hip fracture
Fuente:Bmc Geriatrics
Tipo de trabajo:Estudio de cohortes
Extracto:
Our study suggests beneficial relationships of geriatric treatment
after hip fracture with a) the risk of second hip fractures during the first
months after discharge and b) an improvement of anti-osteoporotic drug treatment.
Claves:Anti-osteoporotic drugs, Geriatric, Hip fracture, Rehabilitation, Second fracture
Cita:BMC Geriatr 2024 May 4; 24 (1) : 395.
Autor/es:Rapp, Kilian (a) Roigk, Patrick (b)
institución:(a) Department of Clinical Gerontology, Robert-Bosch-Hospital, Stuttgart, Germany. (b) Department of Clinical Gerontology, Robert-Bosch-Hospital, Stuttgart, Germany.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Effect of young age (below 40 years) on oncologic outcomes in Lebanese patients with breast cancer
Effect of young age (below 40 years) on oncologic outcomes in Lebanese patients with breast cancer
Fuente:Bmc Cancer
Tipo de trabajo:Estudio de cohortes
Extracto:
Data in the literature is controversial on the effect of
young age on breast cancer prognosis. Our findings could not demonstrate that age
is an independent prognostic factor in our population. There is a need for
outcomes from larger, prospective series that have longer follow-ups and more
data from our region.
Claves:Breast cancer, Prognosis, Recurrence, Survival, Young age
Cita:BMC Cancer 2024 May 4; 24 (1) : 560.
Autor/es:Sbaity, Eman (a) Tamim, Hani (b)
institución:(a) Department of Surgery, American University of Beirut Medical Center, P.O. Box: 11-0236, Riad El-Solh, Beirut, 1107 2020, Lebanon. es25@aub.edu.lb. (b) Department of Internal Medicine, American University of Beirut Medical Center, Beirut, Lebanon.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Patient experiences of information-sharing and patient-centred care across the broad landscape of primary care practice and provision: a nationally representative survey of Australian adults.
Patient experiences of information-sharing and patient-centred care across the broad landscape of primary care practice and provision: a nationally representative survey of Australian adults.
Fuente:Bmc Primary Care
Extracto:
Public health and health services researchers, policymakers
and leaders of primary care professions have a role and responsibility to ensure
practitioners are confident and competent in sharing health information with
their patients that considers their health literacy needs, and the importance of
patient-centred care. Research focussed on a more in-depth understanding of the
differences and relationships observed across the primary care landscape in this
study is recommended.
institución:(a) ARCCIM, School of Public Health, Faculty of Health, University of Technology Sydney, 235-253 Jones St, Ultimo, NSW, Australia. Amie.steel@uts.edu.au. (b) ARCCIM, School of Public Health, Faculty of Health, University of Technology Sydney, 235-253 Jones St, Ultimo, NSW, Australia.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Relationship between circulating FSH levels and body composition and bone health in patients with prostate cancer who undergo androgen deprivation therapy: The BLADE study.
Relationship between circulating FSH levels and body composition and bone health in patients with prostate cancer who undergo androgen deprivation therapy: The BLADE study.
Fuente:Elife
Tipo de trabajo:Revisión
Extracto:
FSH serum levels after ADT
could have an impact on body composition, in particular on FBM. Therefore, FSH
could be a promising marker to monitor the risk of sarcopenic obesity and to
guide the clinicians in the tailored evaluation of body composition in PC
patients undergoing ADT. FUNDING: This research was partially funded by Ferring
Pharmaceuticals. The funder had no role in design and conduct of the study,
collection, management, analysis, and interpretation of the data and in
preparation, review, or approval of the manuscript. CLINICAL TRIAL NUMBER:
clinicalTrials.gov NCT03202381, EudraCT Number 2016-004210-10.
Claves:FSH, androgen deprivation, body composition, bone, human, medicine, prostate cancer
Cita:Elife 2024 Apr 24; 13
Autor/es:Bergamini, Marco (a) Dalla Volta, Alberto (b)
institución:(a) Medical Oncology Unit, ASST Spedali Civili, Department of Medical and Surgical Specialties, Radiological Sciences and Public Health, University of Brescia, Brescia, Italy. (b) Medical Oncology Unit, ASST Spedali Civili, Department of Medical and Surgical Specialties, Radiological Sciences and Public Health, University of Brescia, Brescia, Italy.
Conflicto:MB, AD, CP, SZ, LT, MZ, ML, ND, IC, RB, FV, PB, AG, DF, AA, CS, GM, AB No competing interests declared, LR L Rinaudo is affiliated with Tecnologie Avanzate S.r.l. The author has no financial interests to declare
Preconception underweight impact on postnatal osteoporotic fracture
Preconception underweight impact on postnatal osteoporotic fracture
Fuente:Bmc Pregnancy and Childbirth
Tipo de trabajo:Estudio de cohortes
Extracto:
Appropriate
control of preconception weight might be critical to improving the postpartum
quality of life, subsequent bone health, and neonatal care environment.
Claves:Fracture, Osteoporosis, Preconception care, Pregnancy, Underweight
institución:(a) Division of Maternal Medicine, Center for Maternal-Fetal, Neonatal and Reproductive Medicine, National Center for Child Health and Development, Tokyo, Japan. kaneko-ky@ncchd.go.jp. (b) Department of Health Policy, National Center for Child Health and Development, Tokyo, Japan.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Sexual and gender minority content in undergraduate medical education in the United States and Canada: current state and changes since 2011.
Sexual and gender minority content in undergraduate medical education in the United States and Canada: current state and changes since 2011.
Fuente:Bmc Medical Education
Extracto:
Compared to a 2011 study, the median reported time dedicated to
LGBTQI + health-related topics in 2022 increased across US and Canadian UME
institutions, but the breadth, efficacy, or quality of instruction continued to
vary substantially. Despite the increased hours, this still falls short of the
number of hours based on recommended LGBTQI + health competencies from the
Association of American Medical Colleges. While most deans of medical education
reported their institutions' coverage of LGBTQI + health as 'fair,' 'good,' or
'very good,' there continues to be a call from UME leadership to increase
curricular content. This requires dedicated training for faculty and students.
Claves:LGBTQ persons, Undergraduate medical education
Cita:BMC Med Educ 2024 May 1; 24 (1) : 482.
Autor/es:Streed, Carl G Jr (a) Michals, Amy (b)
institución:(a) Section of General Internal Medicine, Department of Medicine, Boston University Chobanian and Avedisian School of Medicine, 801 Massachusetts Ave., Room 2082, Boston, MA, 02118, USA. Carl.Streed@bmc.org. (b) GenderCare Center, Boston Medical Center, Boston, MA, USA. Carl.Streed@bmc.org.
Conflicto:Dr. Streed received consultation fees from EverlyWell, L’Oreal, the Research Institute for Gender Therapeutics, and the Texas Health Institute on topics unrelated to this work. Dr. Obedin-Maliver received consultation fees from Ibis Reproductive Health, Hims Inc., Folx Health Inc., and Sage Therapeutics on topics unrelated to this work. Dr. Lunn received consultation fees from Hims Inc., Folx Health Inc., Otsuka...
ka Pharmaceutical Development and Commercialization, Inc., and the American Dental Association on topics unrelated to this work.
The Effectiveness of a Lactobacilli-Based Probiotic Food Supplement on Bone Mineral Density and Bone Metabolism in Australian Early Postmenopausal Women: Protocol for a Double-Blind Randomized Placebo-Controlled Trial.
The Effectiveness of a Lactobacilli-Based Probiotic Food Supplement on Bone Mineral Density and Bone Metabolism in Australian Early Postmenopausal Women: Protocol for a Double-Blind Randomized Placebo-Controlled Trial.
Fuente:Nutrients
Extracto:
The trial is
registered with Australian New Zealand Clinical Trials Registry
(ACTRN12621000810819).
Claves:bone mineral density, gut microbiota, lactobacillus, postmenopausal women, probiotics, study protocol
Cita:Nutrients 2024 Apr 12; 16 (8)
Autor/es:Resciniti, Stephanie M (a) Biesiekierski, Jessica R (b)
institución:(a) Department of Food, Nutrition and Dietetics, La Trobe University, Bundoora, VIC 3086, Australia. (b) Department of Food, Nutrition and Dietetics, La Trobe University, Bundoora, VIC 3086, Australia.
Conflicto:This research was funded by Probi. The funder had no role in the study design, data collection, analysis, nor interpretation of results.
Mortality and re-fracture rates in low trauma hip fracture.
Mortality and re-fracture rates in low trauma hip fracture.
Fuente:Bmc Geriatrics
Tipo de trabajo:Estudio de cohortes
Extracto:
Patients with low-trauma hip fractures have shown a high rate of mortality in the
first year. Considering the increase in the incidence of hip fractures with age,
comprehensive strategies are needed to prevent fractures caused by minor trauma
in the elderly population.
Claves:Death, Hip fracture, Incidence, One-year survival, Osteoporosis, Re-fracture
institución:(a) Department of Epidemiology, School of Public Health, Iran University of Medical Sciences, Tehran, Iran. (b) Osteoporosis Research Center, Endocrinology and Metabolism Clinical Sciences Research Institute, Tehran University of Medical Sciences, Tehran, Iran.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Association of osteoporotic fractures of femoral neck and femoral neck geometric parameters in native Chinese women.
Association of osteoporotic fractures of femoral neck and femoral neck geometric parameters in native Chinese women.
Fuente:Bmc Musculoskeletal Disorders
Extracto:
These results suggest that the majority of
osteoporotic fractures of the femoral neck of native Chinese women occur in
patients with osteoporosis. CT thinning or BR increase of FNGPs may be
independent predictors of fragility fracture of femoral neck in native Chinese
women unrelated to BMD.
Cita:BMC Musculoskelet Disord 2024 May 3; 25 (1) : 349.
Autor/es:Li, Lin (a) Shen, Yi (b)
institución:(a) National Clinical Research Center for Metabolic Diseases, Hunan Provincial Key Laboratory of Metabolic Bone Diseases, Department of Metabolism and Endocrinology, The Second Xiangya, Hospital of Central South University, Changsha, 410011, China. (b) Department of Endocrinology and Metabolism, The Affiliated Changsha Hospital of Xiangya School of Medicine, Central South University, Changsha, China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
The role of traditional Chinese medicine on fracture surgery, hospitalization, and total mortality risks in diabetic patients with osteoporosis.
The role of traditional Chinese medicine on fracture surgery, hospitalization, and total mortality risks in diabetic patients with osteoporosis.
Fuente:Plos One
Tipo de trabajo:Estudio de cohortes
Extracto:
This study provides longitudinal evidence through
a cohort study of the value of integrated TCM for T2DOP. More research is needed
to fully understand the clinical significance of these results.
Cita:PLoS One 2024; 19 (5) : e0289455.
Autor/es:Liu, Yi-Chen (a) Chung, Chi-Hsiang (b)
institución:(a) Department of Internal Medicine, Division of Endocrinology and Metabolism, Tri-Service General Hospital, School of Medicine, National Defense Medical Center, Taipei, Taiwan, ROC. (b) School of Public Health, National Defense Medical Center, Taipei, Taiwan, ROC.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Age and sex are excellent predictors of bone complications in patients with type 2 diabetes with no history of osteoporotic fracture or treatment for osteoporosis.
Age and sex are excellent predictors of bone complications in patients with type 2 diabetes with no history of osteoporotic fracture or treatment for osteoporosis.
Fuente:The Journal of International Medical Research
Extracto:
Older women have the highest risk of osteopenia and osteoporosis
among patients with T2DM who have no history of fracture or osteoporosis
treatment. These patients should undergo intensive monitoring for bone fragility
from an early stage of their disease.
Claves:Bone mineral density, dual X-ray absorptiometry, osteopenia, osteoporosis, trabecular bone score, type 2 diabetes
Cita:J Int Med Res 2024 May; 52 (5) : 3000605241246743.
Autor/es:Yamamoto, Yutaro (a) Matsuba, Ren (b)
institución:(a) Department of Metabolism and Endocrinology, St. Marianna University Yokohama Seibu Hospital, Yokohama, Japan. (b) Department of Metabolism and Endocrinology, St. Marianna University Yokohama Seibu Hospital, Yokohama, Japan.
Conflicto:Declaration of conflicting interestThe authors declare that there is no conflict of interest.
Journal of the American Medical Directors Association
Selección SIIC: 9 Mayo, 2024
Journal of the American Medical Directors Association
Association Between Visual Acuity and Prospective Fall Risk in Generally Healthy and Active Older Adults: The 3-Year DO-HEALTH Study.
Association Between Visual Acuity and Prospective Fall Risk in Generally Healthy and Active Older Adults: The 3-Year DO-HEALTH Study.
Fuente:Journal of The American Medical Directors Association
Tipo de trabajo:Estudio aleatorizado y controlado
Extracto:
AND IMPLICATIONS: Our findings suggest that decreased VA is an
independent predictor of an about 20% increased risk of all and injurious falls,
highlighting the importance of regular eye examinations and VA measurements for
fall prevention, even in generally healthy and active older adults.
Claves:DO-HEALTH, falls, injurious falls, older adults, visual acuity
Cita:J Am Med Dir Assoc 2024 May; 25 (5) : 789-795.e2.
Autor/es:Wieczorek, Maud (a) Isler, Marlis (b)
institución:(a) Centre on Aging and Mobility, University of Zurich and City Hospital Zurich, Zurich, Switzerland; Department of Aging Medicine and Aging Research, University of Zurich, Zurich, Switzerland. (b) Centre on Aging and Mobility, University of Zurich and City Hospital Zurich, Zurich, Switzerland.
Conflicto:Disclosure As part of the DO-HEALTH independent and investigator-initiated clinical trial, H.A.B.-F. reports, as the principal investigator of the DO-HEALTH trial, grants from the European Commission, the University of Zurich, Nestec, Pfizer Consumer Healthcare, and Streuli Pharma, and nonfinancial support from DSM Nutritional Products and Roche Diagnostics. Further, H.A.B.-F. reports speaker fees from Wild, Pfizer, Vifor, Mylan, Roche Diagnostics, and...
independent and investigator-initiated grants from Pfizer and from Vifor, outside of the submitted work. E.J.O. was also funded by DO-HEALTH. J.A.K. is a director of Osteoporosis Research Ltd. that maintains FRAX. M.D.B. reports speaking engagements for Roche Pharma (Schweiz) AG and consulting roles for Hoffmann-La Roche Ltd., Roche Pharma (Schweiz) AG, and ZEISS meditec (Deutschland). He is a lead user for Oertli (Schweiz) and holds patents and equity in Ophthorobotics AG. His contracted research includes work with Roche Pharma (Schweiz) AG, Novertis Pharma Schweiz AG, Chengdu Kanghong, and Bayer (Schweiz) AG. He has also received grant support from the W.H. Spross Stiftung zur Förderung der Augenheilkunde and the Stiftung für wissenschaftliche Forschung am Stadtspital Zürich. All other authors declare no competing interests.
Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition
Selección SIIC: 9 Mayo, 2024
Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition
[New Progress in Longitudinal Research on the Risk Factors for Cholelithiasis].
[New Progress in Longitudinal Research on the Risk Factors for Cholelithiasis].
Fuente:Sichuan Da Xue Xue Bao. Yi Xue Ban = Journal of Sichuan University. Medical Science Edition
Extracto:
This
study provides thorough and comprehensive ideas for research concerning the
pathogenesis of cholelithiasis, supplying the basis for identifying high-risk
groups and formulating relevant prevention strategies.
Cita:Sichuan Da Xue Xue Bao Yi Xue Ban 2024 Mar 20; 55 (2) : 490-500.
Autor/es:Wang, Xin (a) Bai, Ye (b)
institución:(a) / ( 610041) West China School of Public Health and West China Fourth Hospital, Sichuan University, Chengdu 610041, China. (b) / ( 610041) West China School of Public Health and West China Fourth Hospital, Sichuan University, Chengdu 610041, China.
Tumor-associated macrophage subtypes on cancer immunity along with prognostic analysis and SPP1-mediated interactions between tumor cells and macrophages.
Tumor-associated macrophage subtypes on cancer immunity along with prognostic analysis and SPP1-mediated interactions between tumor cells and macrophages.
Fuente:Plos Genetics
Extracto:
Some specific macrophage subtypes
were associated with immunotherapy resistance and prognosis in some cancer types.
Cita:PLoS Genet 2024 Apr; 20 (4) : e1011235.
Autor/es:Xu, Liu (a) Chen, Yibing (b)
institución:(a) MOE Key Laboratory of Laser Life Science & Institute of Laser Life Science, College of Biophotonics, South China Normal University, Guangzhou, China. (b) Genetic and Prenatal Diagnosis Center, Department of Gynecology and Obstetrics, First Affiliated Hospital, Zhengzhou University, Zhengzhou, China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación