Daniela Recabarren-Leiva *

Autora invitada por SIIC

El trabajo contribuye a simplificar la detección de las micropartículas y de esta manera explicar uno de los factores desencadenantes de las enfermedades cardiovasculares

ENFERMEDADES CARDIOVASCULARES Y MICROPARTÍCULAS DERIVADAS DE PLAQUETAS

En caso de haber sufrido una enfermedad cardiovascular y cuando no se encuentra una causa probable, es vital comenzar un estudio para determinar el grado de activación plaquetaria.

*Daniela Recabarren-Leiva
describe para SIIC los aspectos relevantes de su trabajo
STANDARDIZATION OF A FAST AND EFFECTIVE METHOD FOR THE GENERATION AND DETECTION OF PLATELET-DERIVED MICROPARTICLES BY A FLOW CYTOMETER
Institución principal de la investigación
*Universidad de Talca, Talca, Chile
Imprimir nota

Referencias bibliográficas
1. A. Sloan, P. Gona, A.D. Johnson, Cardiovascular correlates of platelet count and volume in the Framingham Heart Study, Annals of epidemiology 25(7) :492-8, 2015.
2. U. Flierl, J. Bauersachs, A. Schafer, Modulation of platelet and monocyte function by the chemokine fractalkine (CX3 CL1) in cardiovascular disease, European journal of clinical investigation 45(6) 624-33, 2015.
3. Semple JW, Italiano JE, Jr., Freedman J. Platelets and the immune continuum. Nat Rev Immunol;11(4):264-74, 2011.
4. Kaushansky K. Lineage-Specific Hematopoietic Growth Factors. New England Journal of Medicine;354(19):2034-45, 2006.
5. Gawaz M, Langer H, May AE. Platelets in inflammation and atherogenesis. J Clin Invest;115(12):3378-84, 2005.
6. Gowert NS, Donner L, Chatterjee M, Eisele YS, Towhid ST, Munzer P, et al. Blood platelets in the progression of Alzheimer's disease. PLoS One;9(2):e90523, 2014.
7. Palomo I, Pereira J, Palma J, Alarcón M, Aldunate J, Alfaro J, et al. Hematología: Fisiología y diagnóstico. Talca. 782 p., 2009.
8. Abrams C, Ellison N, Budzynski A, Shattil S. Direct detection of activated platelets and platelet-derived microparticles in humans. Blood;75(1):128-38, 1990.
9. Puddu P, Puddu GM, Cravero E, Muscari S, Muscari A. The involvement of circulating microparticles in inflammation, coagulation and cardiovascular diseases. Can J Cardiol;26(4):140-5, 2010.
10. Suades R, Padro T, Vilahur G, Badimon L. Circulating and platelet-derived microparticles in human blood enhance thrombosis on atherosclerotic plaques. Thromb Haemost;108(6):1208-19, 2012.
11. Apweiler R, Aslanidis C, Deufel T, Gerstner A, Hansen J, Hochstrasser D, et al. Approaching clinical proteomics: Current state and future fields of application in cellular proteomics. Cytometry Part A;75A(10):816-32, 2009.
12. Shantsila E, Montoro-García S, Gallego P, Lip GYH. Circulating microparticles: challenges and perspectives of flow cytometric assessment. Thrombosis and Haemostasis;111(6):1009-14, 2014.
13. Burnier L, Fontana P, Kwak BR, Angelillo-Scherrer A. Cell-derived microparticles in haemostasis and vascular medicine. Thromb Haemost;101(3):439-51, 2009.
14. Barteneva NS, Fasler-Kan E, Bernimoulin M, Stern JN, Ponomarev ED, Duckett L, et al. Circulating microparticles: square the circle. BMC Cell Biol;14:23, 2013.
15. Duarte D, Taveira-Gomes T, Sokhatska O, Palmares C, Costa R, Negrao R, et al. Increased circulating platelet microparticles as a potential biomarker in asthma. Allergy;68(8):1073-5, 2013.
16. Chaturvedi S, Cockrell E, Espinola R, Hsi L, Fulton S, Khan M, et al. Circulating microparticles in patients with antiphospholipid antibodies: Characterization and associations. Thrombosis Research;135(1):102-8, 2015.
17. Laresche C, Pelletier F, Garnache-Ottou F, Lihoreau T, Biichle S, Mourey G, et al. Increased Levels of Circulating Microparticles Are Associated with Increased Procoagulant Activity in Patients with Cutaneous Malignant Melanoma. J Invest Dermatol;134(1):176-82, 2014.
18. Punyadee N, Mairiang D, Thiemmeca S, Komoltri C, Pan-ngum W, Chomanee N, et al. Microparticles in Dengue Infection Provide a Novel Biomarker to Predict Severe Clinical Outcomes. Journal of Virology, 2014.
19. Wong AE, Kwaan HC, Grobman WA, Weiss I, Wong CA. Microparticle source and tissue factor expression in pregnancy. Ann Hematol, 2015.
20. Agouni A, Lagrue-Lak-Hal AH, Ducluzeau PH, Mostefai HA, Draunet-Busson C, Leftheriotis G, et al. Endothelial dysfunction caused by circulating microparticles from patients with metabolic syndrome. Am J Pathol 2008;173(4):1210-9, 2008.
21. Distler JH, Jungel A, Huber LC, Seemayer CA, Reich CF, 3rd, Gay RE, et al. The induction of matrix metalloproteinase and cytokine expression in synovial fibroblasts stimulated with immune cell microparticles. Proc Natl Acad Sci U S A;102(8):2892-7, 2005.
22. Montoro-Garcia S, Shantsila E, Wrigley BJ, Tapp LD, Abellan Aleman J, Lip GY. Small-size Microparticles as Indicators of Acute Decompensated State in Ischemic Heart Failure. Rev Esp Cardiol (Engl Ed). 2015.
23. Chou YIS, Kong J, Song R, Yan L, Zheng L, Zhang Y. Correlations of platelet- derived microparticles with thromboxane B2, platelet-activating factor, endothelin-1, and neutrophil to lymphocyte ratio in patients with coronary intermediate lesions. Biomarkers;19(8):684-92, 2014.
24. Meziani F, Tesse A, Andriantsitohaina R. Microparticles are vectors of paradoxical information in vascular cells including the endothelium: role in health and diseases. Pharmacol Rep.;60(1):75-84, 2008.
25. Benameur T, Andriantsitohaina R, Martinez MC. Therapeutic potential of plasma membrane-derived microparticles. Pharmacol Rep;61(1):49-57, 2009.
26. Varon D, Shai E. Role of platelet-derived microparticles in angiogenesis and tumor progression. Discov Med. 2009;8(43):237-41, 2009.
27. Prokopi M, Pula G, Mayr U, Devue C, Gallagher J, Xiao Q, et al. Proteomic analysis reveals presence of platelet microparticles in endothelial progenitor cell cultures. Blood;114(3):723-32, 2009.
28. Barry OP, Kazanietz MG, Pratico D, FitzGerald GA. Arachidonic acid in platelet microparticles up-regulates cyclooxygenase-2-dependent prostaglandin formation via a protein kinase C/mitogen-activated protein kinase-dependent pathway. J Biol Chem;274(11):7545-56, 1999.
29. Montoro-García S, Shantsila E, Hernández-Romero D, Jover E, Valdés M, Marín F, et al. Small-size platelet microparticles trigger platelet and monocyte functionality and modulate thrombogenesis via P-selectin. British Journal of Haematology, 2014.