Hua Yan, author's report for SIIC / crónica del autor para SIIC

      ELEVATED INTRAVITREAL IL-1BETA AND IL-10 LEVELS IN PDR
In order to determine the roles of IL-1beta and IL-10 in the vitreous of PDR, we measured IL-1beta and IL-10 concentration by ELISA. We found vitreous levels of IL-1beta and IL-10 were upregulated in PDR patients, and these two cytokines play roles in regulating the development and progression of PDR..

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Indian Journal of Ophthalmology 

Hua Yan (author)
Tianjin, China  (author's city and country) / Tianjin, China (ciudad y país del autor/a)

Yan Chen, author's report for SIIC / crónica del autor para SIIC

      BONE TURNOVER AND ARTICULAR CARTILAGE DIFFERENCES IN PATIENTS WITH KNEE OSTEOARTHRITIS
Subchondral bone cysts (SBCs) may contribute to knee osteoarthritis (OA) pathogenesis. SBCs within knee OA are characterized by focally increased bone turnover, altered bone structure and more severe articular cartilage damage. The increased bone turnover possibly contributes to altered bone structure localized in SBC areas, and thus aggravates articular cartilage degeneration..

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Osteoarthritis and Cartilage 

Yan Chen (author)
Hong Kong, China  (author's city and country) / Hong Kong, China (ciudad y país del autor/a)

Jeonghwna Lee, author's report for SIIC / crónica del autor para SIIC

      RAPID CORRECTION RATE OF HYPONATREMIA AFTER LIVER TRANSPLANTATION
The correction rate of hyponatremia and fast correction rate of hyponatremia were significantly associated with post-transplant neurological complications. Rapid correction of hyponatremia was an independent risk factor for the development of post-transplant neurological complications..

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Tohoku Journal of Experimental Medicine 

Jeonghwna Lee (author)
Seoul, Corea del Sur  (author's city and country) / Seoul, Corea del Sur (ciudad y país del autor/a)

Dong-seon Kim, author's report for SIIC / crónica del autor para SIIC

      ANTIPLATELET AND ANTITHROMBOTIC HERBAL COMBINATION WITH SYNERGISTIC EFFECT
Combinational preparations of Phyllostachys pubescens leaves (PL) and mume fructus (MF), and especially their 2:1 combination, can increase antiplatelet and anti-thrombosis effects more than PL and MF alone, offering evidence for a potential novel combination anti-thrombic therapy..

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Integrative Medicine Research 

Dong-seon Kim (author)
Daejeon, Corea del Sur  (author's city and country) / Daejeon, Corea del Sur (ciudad y país del autor/a)

Sung Oh Hwang, author's report for SIIC / crónica del autor para SIIC

      CARDIOPULMONARY RESUSCITATION: FROM THE PAST INTO THE FUTURE
Several important components of cardiopulmonary resuscitation (CPR) have been determined with a lack of scientific basis. Additional investigations to determine the most effective CPR method are necessary to overcome current CPR controversies and introduction of internet or ubiquitous technology to resuscitation medicine is needed to improve the survival rate of cardiac arrest..

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Journal of Acute Medicine 

Sung Oh Hwang (author)
Wonju, Corea del Sur  (author's city and country) / Wonju, Corea del Sur (ciudad y país del autor/a)

Chan Sup Shim, author's report for SIIC / crónica del autor para SIIC

      ENDOSCOPIC BOTULINUM TOXIN INJECTION: BENEFIT AND LIMITATION
Endoscopic treatment for achalasia is directed at disrupting or weakening the lower esophageal sphincter (LES). As botulinum toxin (botox) is a potent inhibitor of acetylcholine release from nerve endings. The response rates at 1 month following administration are 78% on average (range, 63%-90%)..

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Gastrointestinal Intervention 

Chan Sup Shim (author)
Seoul, Corea del Sur  (author's city and country) / Seoul, Corea del Sur (ciudad y país del autor/a)

James F. List, author's report for SIIC / crónica del autor para SIIC

      T2DM: DAPAGLIFLOZIN, METFORMIN XR, OR BOTH
In treatment-naïve patients with type 2 diabetes (T2D), initial combination therapy with dapagliflozin + extended-release metformin (MET XR) resulted in significant improvements in glycaemic and weight outcomes. Dapagliflozin + MET XR provided superior glycaemic benefits to monotherapy with either agent. The combination treatment was generally well tolerated..

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International Journal of Clinical Practice 

James F. List (author)
Princeton, New Jersey, United States  (author's city and country) / Princeton, New Jersey, United States (ciudad y país del autor/a)

Priyanka Jadhav, author's report for SIIC / crónica del autor para SIIC

      INNOVATIVE APPROACHES TO NOVEL SCAFFOLDS AND STRATEGIES FOR INFECTIOUS DISEASES
Our study indicates validity of claims in Ayurved, if medicinal plants selected on basis of its documented use, it leads to more hits which can be scientifically manipulated to find therapies for diseases. In treating infectious diseases, we hope ancient science can contribute to find solutions in developing countries..

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Chronicles of Young Scientists 

Priyanka Jadhav (author)
Gainesville, United States  (author's city and country) / Gainesville, United States (ciudad y país del autor/a)

Wissam Bleibel, author's report for SIIC / crónica del autor para SIIC

      HEPATIC ENCEPHALOPATHY
A high percentage of patients with chronic liver disease progresses to cirrhosis complicated by hepatic encephalopathy (HE). This presents with neurological impairments ranging from subclinical dysfunction to coma. Its management is based on eliminating the precipitating factors and decreasing the toxin load with adequate bowel motions or altering bowel flora..

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Saudi Journal of Gastroenterology 

Wissam Bleibel (author)
Owensboro, United States  (author's city and country) / Owensboro, United States (ciudad y país del autor/a)

Eric Rubenstein, author's report for SIIC / crónica del autor para SIIC

      QUALITY CONTROL AT THE ENDOPLASMIC RETICULUM TRANSLOCON
The essential Sec61 translocon brings proteins into and across the endoplasmic reticulum membrane. Little was known about how proteins blocking this channel are removed. New data reveal that the Hrd1 ubiquitin ligase degrades proteins that persistently and abnormally engage Sec61. This quality control pathway may also regulate low-density lipoprotein particle synthesis..

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The Journal of Cell Biology 

Eric Rubenstein (author)
New Haven, United States  (author's city and country) / New Haven, United States (ciudad y país del autor/a)

Eric Rubenstein, author's report for SIIC / crónica del autor para SIIC

      QUALITY CONTROL AT THE ENDOPLASMIC RETICULUM TRANSLOCON
The essential Sec61 translocon brings proteins into and across the endoplasmic reticulum membrane. Little was known about how proteins blocking this channel are removed. New data reveal that the Hrd1 ubiquitin ligase degrades proteins that persistently and abnormally engage Sec61. This quality control pathway may also regulate low-density lipoprotein particle synthesis..

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The Journal of Cell Biology 

Eric Rubenstein (author)
New Haven, United States  (author's city and country) / New Haven, United States (ciudad y país del autor/a)