Scarce resources, public health and professional care: the COVID-19 pandemic exacerbating bioethical conflicts - findings from global qualitative expert interviews.

Scarce resources, public health and professional care: the COVID-19 pandemic exacerbating bioethical conflicts - findings from global qualitative expert interviews.

Fuente:Bmc Public Health

Extracto: The pandemic exposed pre-existing structural problems in LMICs and HICs. Without neglecting individual contextual factors in the observed countries, we created a mosaic of different voices of experts in bioethics across the globe, drawing attention to the need for international solidarity in the context of a global crisis.

Claves:Bioethics, COVID-19, Experts, Global Comparison, Pandemic, Qualitative Interviews, Vulnerability

Cita:BMC Public Health 2023 Dec 13; 23 (1) : 2492.

Autor/es:Vonderschmitt, Jane (a)
Wöhlke, Sabine (b)

institución:(a) Department of Medical Ethics and History of Medicine, University Medical Center Goettingen, Humboldtallee 36 / 37073, Goettingen, Germany. j.vonderschmitt@stud.uni-goettingen.de.
(b) Department of Health Sciences, Hamburg University of Applied Sciences, Ulmenliet 20 / 21033, Hamburg, Germany.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1186/s12889-023-17249-4

Impact of digital assistive technologies on the quality of life for people with dementia

Impact of digital assistive technologies on the quality of life for people with dementia

Fuente:Bmj Open

Tipo de trabajo:Revisión

Extracto: We intend to publish our findings in a peer-reviewed journal.

Claves:Ageing, Dementia, Information technology, Patient-centred care, Public health, Quality of life

Cita:BMJ Open 2023 Dec 13; 13 (12) : e077017.

Autor/es:Schneider, Charlotte (a)
Kowatsch, Tobias (b)

institución:(a) Department of Management, Technology and Economics, ETH Zürich, Zurich, Switzerland.
(b) Department of Management, Technology and Economics, ETH Zürich, Zurich, Switzerland.

Conflicto:Competing interests: TK is affiliated with the Centre for Digital Health Interventions (CDHI), a joint initiative of the Institute for Implementation Science in Health Care, University of Zurich; the Department of Management, Technology and Economics at ETH Zurich; and the Institute of Technology Management and School of Medicine at the University of St. Gallen. CDHI is funded in part by... CSS, a Swiss health insurer. TK is also a cofounder of Pathmate Technologies, a university spin-off company that creates and delivers digital clinical pathways. However, neither CSS nor Pathmate Technologies was involved in this research. All other authors declare no conflict of interest.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1136/bmjopen-2023-077017

Precision cancer medicine and the doctor-patient relationship

Precision cancer medicine and the doctor-patient relationship

Fuente:Bmc Medical Informatics and Decision Making

Tipo de trabajo:Revisión sistemática

Extracto: Many findings have previously been addressed in doctor-patient communication and clinical genetics. However, precision medicine adds complexity to these fields and further emphasizes the importance of clear communication on specific themes like the distinction between genomic and gene expression and patients' expectations about access, eligibility, effectiveness, and side effects of targeted therapies.

Claves:Cancer, Communication, Doctor-patient relation, Narrative synthesis, Oncology, Precision medicine, Shared-decision making, Systematic review

Cita:BMC Med Inform Decis Mak 2023 Dec 14; 23 (1) : 286.

Autor/es:Grauman, Å (a)
Ancillotti, M (b)

institución:(a) Centre for Research Ethics and Bioethics, Uppsala University, Box 564, Uppsala, SE-751 22, Sweden. asa.grauman@crb.uu.se.
(b) Centre for Research Ethics and Bioethics, Uppsala University, Box 564, Uppsala, SE-751 22, Sweden.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1186/s12911-023-02395-x

Genomics-informed nursing strategies and health equity

Genomics-informed nursing strategies and health equity

Fuente:Plos One

Tipo de trabajo:Revisión

Extracto: The identification of nursing strategies to address health disparities will build the foundation for policy and practice to ensure that the integration of genomic technologies benefits everyone.

Cita:PLoS One 2023; 18 (12) : e0295914.

Autor/es:Dordunoo, Dzifa (a)
Limoges, Jacqueline (b)

institución:(a) University of Victoria, School of Nursing, Director, Centre for Evidence informed Nursing and Health Care: JBI Centre of Excellence, Victoria, Canada.
(b) Athabasca University, Chair, Ontario Cancer Research Ethics Board, Toronto, Canada.

Conflicto:The authors have declared no competing interests exist.

Formato:Informe virtual

Idioma:Inglés

País de fuente:EE.UU.

Sitio web:http://dx.doi.org/10.1371/journal.pone.0295914

Patient experience of a virtual reality calm room in a psychiatric inpatient care setting in Sweden: a qualitative study with inpatients.

Patient experience of a virtual reality calm room in a psychiatric inpatient care setting in Sweden: a qualitative study with inpatients.

Fuente:Bmj Open

Extracto: VR technology has the potential to solve pressing logistic issues in offering calm rooms in psychiatric inpatient care. VR calm rooms appear to be appreciated by psychiatric inpatients, who value their accessibility, convenience and variety of modalities offered. Participants perceived an increase in their well-being after use.

Claves:MENTAL HEALTH, PSYCHIATRY, Virtual Reality

Cita:BMJ Open 2023 Dec 14; 13 (12) : e076285.

Autor/es:Ilioudi, Maria (a)
Wallström, Sara (b)

institución:(a) Region Västra Götaland, Sahlgrenska University Hospital, Psychiatric Department, Goteborg, Sweden.
(b) Institute of Health and Care Sciences, Sahlgrenska Academy, University of Gothenburg, Gotheborg, Sweden.

Conflicto:Competing interests: PL reports having received minor consulting fees from Mimerse, the company that developed the VR application used. Mimerse is no longer an active company.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1136/bmjopen-2023-076285

Resurgence of syphilis: focusing on emerging clinical strategies and preclinical models.

Resurgence of syphilis: focusing on emerging clinical strategies and preclinical models.

Fuente:Journal of Translational Medicine

Extracto: This review aims to provide a comprehensive summary of the most recent syphilis tactics, including detection, drug resistance treatments, vaccine development, and preclinical models in clinical practice.

Claves:Diagnosis, Drug resistance, Models, Syphilis, Treponema pallidum, Vaccine

Cita:J Transl Med 2023 Dec 18; 21 (1) : 917.

Autor/es:Xiong, Shun (a)
Liu, Zhaoping (b)

institución:(a) Institute of Pathogenic Biology and Key Laboratory of Special Pathogen Prevention and Control of Hunan Province, Hengyang Medical College, University of South China, Hengyang, 421001, China.
(b) Institute of Pathogenic Biology and Key Laboratory of Special Pathogen Prevention and Control of Hunan Province, Hengyang Medical College, University of South China, Hengyang, 421001, China.

Conflicto:The authors have declared that no competing interest exists.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1186/s12967-023-04685-4

Evidence for a shared genetic contribution to loneliness and borderline personality disorder.

Evidence for a shared genetic contribution to loneliness and borderline personality disorder.

Fuente:Translational Psychiatry

Extracto: Further research is needed to investigate which genetic mechanisms and pathways are involved in this association and whether a genetic predisposition for loneliness contributes to BPD risk.

Cita:Transl Psychiatry 2023 Dec 18; 13 (1) : 398.

Autor/es:Schulze, Anna (a)
Streit, Fabian (b)

institución:(a) Department of Clinical Psychology, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany. anna.schulze@zi-mannheim.de.
(b) Department of Genetic Epidemiology in Psychiatry, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:EE.UU.

Sitio web:http://dx.doi.org/10.1038/s41398-023-02705-x

Exploring perceptions and operational considerations for use of a smartphone application to self-monitor blood pressure in pregnancy in Lombok, Indonesia: protocol for a qualitative study.

Exploring perceptions and operational considerations for use of a smartphone application to self-monitor blood pressure in pregnancy in Lombok, Indonesia: protocol for a qualitative study.

Fuente:Bmj Open

Tipo de trabajo:Revisión

Extracto: The analyses from this study will also inform the design of a subsequent impact evaluation.

Claves:blood pressure, information technology, maternal medicine, prenatal diagnosis, qualitative research, self care

Cita:BMJ Open 2023 Dec 18; 13 (12) : e073875.

Autor/es:Tamrat, Tigest (a)
Setiyawati, Yuni Dwi (b)

institución:(a) UNDP/UNFPA/UNICEF/WHO/World Bank Special Programme of Research Development and Research Training in Human Reproduction (HRP), Department of Sexual and Reproductive Health and Research, World Health Organization, Geneva, Switzerland tamratt@who.int.
(b) University of Geneva, Geneva, Switzerland.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1136/bmjopen-2023-073875

Diet in relation to Metabolic, sleep and psychological health Status (DiMetS): protocol for a cross-sectional study.

Fuente:Bmj Open

Tipo de trabajo:Revisión

Extracto: Dissemination will be through conference presentations and publications in peer-reviewed journals.

Claves:diabetes & endocrinology, mental health, nutrition & dietetics, sleep medicine

Cita:BMJ Open 2023 Dec 18; 13 (12) : e076114.

Autor/es:Poursalehi, Donya (a)
Shahdadian, Farnaz (b)

institución:(a) Isfahan University of Medical Sciences, Isfahan, Iran (the Islamic Republic of).
(b) Department of Clinical Nutrition, Isfahan University of Medical Sciences, Isfahan, Iran (the Islamic Republic of).

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1136/bmjopen-2023-076114

Health disparities in one of the world's most progressive countries

Health disparities in one of the world's most progressive countries

Fuente:Bmc Public Health

Tipo de trabajo:Revisión

Extracto: Findings of persistent health disparities-despite the relatively long history of SGM supportive policies in the Netherlands-highlight the need for more research and greater attention to population groups that have been underrepresented. Such research would not only provide guidance on strategies to improve the health of SGM people in the Netherlands, but also in other countries that are seeking to reduce health inequities. Addressing SGM health disparities in the Netherlands and elsewhere is complex and requires a multifaceted approach that addresses individual, interpersonal and structural factors.

Claves:Dutch, Health disparities, LGBTQ health, Mental health, Minority stress, SGM health, Sexual and gender minority, Structural stigma, Substance use, The Netherlands

Cita:BMC Public Health 2023 Dec 18; 23 (1) : 2533.

Autor/es:Hughes, Tonda L (a)
Bochicchio, Lauren (b)

institución:(a) School of Nursing, Department of Psychiatry, Columbia University Irving Medical School, Center for Sexual and Gender Minority Health Research, 560 West 168 Street, New York, NY, USA. th2696@cumc.columbia.edu.
(b) Columbia University School of Nursing Center for Sexual and Gender Minority Health Research, 560 West 168th Street, New York, NY, USA.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1186/s12889-023-17466-x

Testing and Practical Implementation of a User-Friendly Personalized and Long-Term Electronic Informed Consent Prototype in Clinical Research: Mixed Methods Study.

Testing and Practical Implementation of a User-Friendly Personalized and Long-Term Electronic Informed Consent Prototype in Clinical Research: Mixed Methods Study.

Fuente:Journal of Medical Internet Research

Extracto: This study provides insights for the implementation of a user-friendly personalized and long-term eIC application. The study findings showed that usability testing is key to assessing and increasing the user-friendliness of an eIC application. Although this eIC system has the potential to be usable by a wide audience, participants with low digital literacy may not be able to use it successfully, highlighting the need for additional support for participants or other alternatives to an eIC system. In addition, key lessons emerging from the interviews included ensuring that the application is easy to implement in practice and is interoperable with other established systems.

Claves:digital health, human-centered design, implementation, informed consent, qualitative research, stakeholders, trial

Cita:J Med Internet Res 2023 Dec 19; 25 : e46306.

Autor/es:De Sutter, Evelien (a)
Geerts, David (b)

institución:(a) Clinical Pharmacology and Pharmacotherapy, Department of Pharmaceutical and Pharmacological Sciences, Catholic University (KU) Leuven, Leuven, Belgium.
(b) Catholic University (KU) Leuven Digital Society Institute, Catholic University (KU) Leuven, Leuven, Belgium.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Canadá

Sitio web:http://dx.doi.org/10.2196/46306

Digital transformation in schools of two southern regions of Sweden through implementation-informed approach: A mixed-methods study protocol.

Digital transformation in schools of two southern regions of Sweden through implementation-informed approach: A mixed-methods study protocol.

Fuente:Plos One

Extracto: The project will build capacity using implementation of educational technology in Swedish educational settings.

Cita:PLoS One 2023; 18 (12) : e0296000.

Autor/es:Masiello, Italo (a)
Fixsen, Dean L (b)

institución:(a) Department of Computer Science and Media Technology, Linnaeus University, Växjö, Sweden.
(b) Active Implementation Research Network, Chapel Hill, NC, United States of America.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:EE.UU.

Sitio web:http://dx.doi.org/10.1371/journal.pone.0296000

The art of equity: critical health humanities in practice.

Fuente:Philosophy, Ethics, and Humanities in Medicine Pehm

Extracto: In this paper, we explore the growing field of critical health humanities and its potential for teaching health equity through narrative practices. We provide concrete examples of educational activities that incorporate critical consciousness and structural competency - frameworks we have found useful for conceptualizing critical health humanities as a pedagogical practice. We also discuss the strengths and challenges of this work and suggest future directions.

Claves:Health equity, Health humanities, Medical education, Narrative medicine, Social determinants of health, Structural competency

Cita:Philos Ethics Humanit Med 2023 Dec 13; 18 (1) : 19.

Autor/es:Mathieu, Irène P (a)
Martin, Benjamin J (b)

institución:(a) Department of Pediatrics; Program in Health Humanities, Center for Health Humanities & Ethics, University of Virginia School of Medicine, PO Box 800386, Charlottesville, VA, 22908, USA. im4uq@uvahealth.org.
(b) Department of Internal Medicine; Program in Health Humanities, Center for Health Humanities & Ethics, University of Virginia School of Medicine, PO Box 800386, Charlottesville, VA, 22908, USA.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1186/s13010-023-00149-1

Brain Death and Organ Transplantation in Nepal: Navigating Cultural, Legal, and Ethical Landscapes.

Fuente:Transplant International Official Journal of The European Society For Organ Transplantation

Extracto: Despite progress, substantial challenges persist requiring evidence-based strategies focused on awareness, capacity building, policy improvements, and culturally appropriate community engagement.

Claves:Nepal, brain death, cultural barriers, ethical considerations, organ transplantation

Cita:Transpl Int 2023; 36 : 11882.

Autor/es:Atreya, Alok (a)
Bastola, Priska (b)

institución:(a) Department of Forensic Medicine, Lumbini Medical College, Palpa, Nepal.
(b) Department of Cardiothoracic and Vascular Anaesthesiology, Maharajgunj Medical Campus, Kathmandu, Nepal.

Conflicto:The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3389/ti.2023.11882

Post-discharge malaria chemoprevention in children admitted with severe anaemia in malaria-endemic settings in Africa

Fuente:The Lancet. Global Health

Tipo de trabajo:Revisión sistemática

Extracto: FUNDING: The Research-Council of Norway and the Bill-&-Melinda-Gates-Foundation through the Worldwide-Antimalarial-Research-Network.

Cita:Lancet Glob Health 2024 Jan; 12 (1) : e33-e44.

Autor/es:Phiri, Kamija S (a)
Khairallah, Carole (b)

institución:(a) School of Global and Public Health, Kamuzu University of Health Sciences (KUHeS), Blantyre, Malawi; Training and Research Unit of Excellence, Blantyre, Malawi.
(b) Department of Clinical Sciences, Liverpool School of Tropical Medicine, Liverpool, UK.

Conflicto:Declaration of interests We declare no competing interests.

Formato:Informe impreso

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1016/S2214-109X(23)00492-8

The eco-ethical contribution of Menico Torchio - a forgotten pioneer of European Bioethics.

Fuente:Philosophy, Ethics, and Humanities in Medicine Pehm

Extracto: Our conclusion will underscore the necessity of understanding the connections between planetary, environmental, and human health.

Claves:Bioethics, Biomedical ethics, Environmental bioethics, Fritz Jahr, Menico Torchio, Van Rensselaer Potter

Cita:Philos Ethics Humanit Med 2023 Dec 20; 18 (1) : 20.

Autor/es:Rincic, Iva (a)
Muzur, Amir (b)

institución:(a) Department of Social Sciences and Medical Humanities, University of Rijeka, Faculty of Medicine; Head, Rijeka, Croatia.
(b) Department of Public Health, University of Rijeka, Faculty of Health Studies, Brace Branchetta 20, 51 000, Rijeka, Croatia.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1186/s13010-023-00145-5

Statins and cognitive decline in patients with Alzheimer's and mixed dementia

Fuente:Alzheimer's Research & Therapy

Tipo de trabajo:Estudio de cohortes

Extracto: Some patients with AD or mixed dementia with indication for lipid-lowering medication may benefit cognitively from statin treatment; however, further research is needed to clarify the findings of sensitivity analyses.

Claves:Alzheimer's disease, Cholesterol metabolism, Cognitive impairment, Cohort study, HMG-CoA reductase inhibitors, Statins

Cita:Alzheimers Res Ther 2023 Dec 20; 15 (1) : 220.

Autor/es:Petek, Bojana (a)
Häbel, Henrike (b)

institución:(a) Division of Neurogeriatrics, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, Stockholm, Sweden. bojana.petek@kclj.si.
(b) Clinical Institute of Genomic Medicine, University Medical Centre Ljubljana, Ljubljana, Slovenia. bojana.petek@kclj.si.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1186/s13195-023-01360-0

Attributes That Influence Human Decision-Making in Complex Health Services

Fuente:Jmir Human Factors

Tipo de trabajo:Revisión

Extracto: The results highlight key themes that underline the complex and nuanced nature of human decision-making. The results suggest that rationality is entrenched and may influence the lexicon of our thinking about decision-making. The results also highlight the counter narrative of decision-making underpinned by uniquely human attributes. This may have ramifications for decision-making in complex health services today. The review itself takes a rational approach, and the methods used were suited to this. INTERNATIONAL REGISTERED REPORT IDENTIFIER (IRRID): RR2-10.2196/42353.

Claves:health policy, health regulation, health services, human attributes, human decision-making, rational decision-making, rationality

Cita:JMIR Hum Factors 2023 Dec 20; 10 : e46490.

Autor/es:Doreswamy, Nandini (a)
Horstmanshof, Louise (b)

institución:(a) Faculty of Health, Southern Cross University, Lismore, Australia.
(b) National Coalition of Independent Scholars, Canberra, Australia.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Canadá

Sitio web:http://dx.doi.org/10.2196/46490

Placebo effects in mental health disorders

Placebo effects in mental health disorders

Fuente:Bmj Open

Tipo de trabajo:Revisión

Extracto: We will publish the results in a peer-reviewed journal.

Claves:PSYCHIATRY, SLEEP MEDICINE, Systematic Review

Cita:BMJ Open 2023 Nov 30; 13 (11) : e073946.

Autor/es:Huneke, Nathan Tm (a)
Amin, Jay (b)

institución:(a) Clinical and Experimental Sciences, University of Southampton Faculty of Medicine, Southampton, UK n.huneke@soton.ac.uk.
(b) Southern Health NHS Foundation Trust, Southampton, UK.

Conflicto:Competing interests: DSB is President of the British Association for Psychopharmacology (BAP) and Editor of Human Psychopharmacology journal (for which he receives an Editor’s honorarium). CMH has acted on an expert advisory board for Neurim pharmaceuticals. ODH is a part-time employee and stock holder of Lundbeck A/s. He has received investigator-initiated research funding from and/or participated in advisory/speaker meetings organised... ed by Angellini, Autifony, Biogen, Boehringer-Ingelheim, Eli Lilly, Heptares, Global Medical Education, Invicro, Jansenn, Lundbeck, Neurocrine, Otsuka, Sunovion, Recordati, Roche and Viatris/Mylan. ODH has a patent for the use of dopaminergic imaging. All other authors declare no competing interests. MS has received honoraria/has been a consultant for Angelini, Lundbeck, Otsuka. SRC receives an honorarium from Elsevier for associate editor work at two academic journals. SCo has received honoraria from non-profit associations (BAP, ACAMH, CADDRA) for educational activities. CUC has been a consultant and/or advisor to or has received honoraria from: AbbVie, Acadia, Adock Ingram, Alkermes, Allergan, Angelini, Aristo, Biogen, Boehringer-Ingelheim, Bristol-Meyers Squibb, Cardio Diagnostics, Cerevel, CNX Therapeutics, Compass Pathways, Darnitsa, Denovo, Gedeon Richter, Hikma, Holmusk, IntraCellular Therapies, Jamjoom Pharma, Janssen/J&J, Karuna, LB Pharma, Lundbeck, MedAvante-ProPhase, MedInCell, Merck, Mindpax, Mitsubishi Tanabe Pharma, Mylan, Neurocrine, Neurelis, Newron, Noven, Novo Nordisk, Otsuka, Pharmabrain, PPD Biotech, Recordati, Relmada, Reviva, Rovi, Sage, Seqirus, SK Life Science, Sumitomo Pharma America, Sunovion, Sun Pharma, Supernus, Takeda, Teva, Tolmar, Vertex and Viatris. He provided expert testimony for Janssen and Otsuka. He served on a Data Safety Monitoring Board for Compass Pathways, Denovo, Lundbeck, Relmada, Reviva, Rovi, Supernus and Teva. He has received grant support from Janssen and Takeda. He received royalties from UpToDate and is also a stock option holder of Cardio Diagnostics, Kuleon Biosciences, LB Pharma, Mindpax and Quantic.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1136/bmjopen-2023-073946

Qualified placebo for trials of herbal medicine treatment in rare diseases? A cross-sectional analysis.

Qualified placebo for trials of herbal medicine treatment in rare diseases? A cross-sectional analysis.

Fuente:Orphanet Journal of Rare Diseases

Tipo de trabajo:Revisión

Extracto: The overall situation of HM-placebo in the field of rare diseases was poor. In particular, the placebo is tied to the quality of trials, and poor placebo hinders the generation of high-quality evidence for herbal clinical trials in the field of rare diseases. We summarize the current methods of assessment involved in the use of placebos and propose various considerations for placebos in different contexts. Our study can greatly promote rare disease researchers to review the quality of their placebo and clinical trials. It is imperative to guarantee that meticulously conducted research generates clinical evidence of the highest caliber. We also expect that in the future, more rigorous relevant standards about the reporting and design of HM-placebo will be developed. High-quality clinical trials are the prerequisite for the wide clinical application of herbal medicines for rare diseases.

Claves:Cross-sectional analysis, Herbal medicine, Placebo, Rare disease, Trials

Cita:Orphanet J Rare Dis 2023 Nov 30; 18 (1) : 373.

Autor/es:Li, Yixuan (a)
Du, Peipei (b)

institución:(a) Dongzhimen Hospital, Beijing University of Chinese Medicine, 5 Haiyuncang Street, Dongcheng District, Beijing, 100070, China.
(b) Dongzhimen Hospital, Beijing University of Chinese Medicine, 5 Haiyuncang Street, Dongcheng District, Beijing, 100070, China.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1186/s13023-023-02987-w