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Jayalakshmi Lingam
describes for SIIC the most significant aspects of his article
describe para SIIC los aspectos relevantes de su artículo

Role of interferon gamma as an immunological marker of tuberculosis

Significance of interferon gamma (IFN-g) in pleural fluid was evaluated in the present study and compared with the biomarker adenosine deaminase (ADA) in the diagnosis of tuberculous effusion. IFN-g in pleural fluid was useful immunological marker with high sensitivity and specificity in the differential diagnosis of pleural effusion.

The article was published by
El artículo fue publicado por
Journal of Dr. NTR University of Health Sciences
Volume / Volumen: 2
Number / Número: 2
First and last pages / Páginas inicial-final: 92-95
Year / Año: 2013
Month / Mes: april

This journal, which is covered by SIIC Data Bases,
is part of the bibliographic collections of the Biblioteca Biomédica (BB) SIIC.
Esta revista, clasificada por SIIC Data Bases,
integra el acervo bibliográfico de la Biblioteca Biomédica (BB) SIIC.

Principal institution where the research took place
Institución principal de la investigación
Government General and Chest Hospital, Hyderabad, Telangana, India

Authors' Report

Crónica del Autor

Bibliographic references
Referencias bibliográficas

1. Crompton GK, McHardy GF. Diseases of the respiratory system. In: Edwards CR, Boucher IA. Davidson's Principles and Practice of Medicine. 16th ed. Edinburgh: ELBS; pp 410-2, 1992.
2. Kim YC, Park KO, Bom HS, Lim SC, Park HK, Na HJ, et al. Combining ADA, protein and IFN-gamma best allows discrimination between tuberculous and malignant effusion. Korean J Intern Med 12:225-31, 1997.
3. Shimokata K, Saka H, Murate T, Hasegawa Y, Hasegawa T. Cytokine content in pleural effusion, comparison between tuberculous and carcinomatous pleurisy. Chest 99:1103-7, 1991.
4. Villegas MV, Labrada LA, Saravia NG. Evaluation of polymerase chain reaction, adenosine deaminase, and interferon-gamma in pleural fluid for the differential diagnosis of pleural tuberculosis. Chest 118:1355-64, 2000.
5. Light RW. Disorders of pleura, mediastinum and diaphragm. In: Braunwald E, Fauci AS, Kasper DL, Hauser SL, Longo DL, Jameson JL. Harrison's principles of internal medicine, vol. 2, 15th ed. New York, McGraw Hill International Edition; pp. 1513-5, 2003.
6. Söderblom T, Nyberg P, Teppo AM, Klockars M, Riska H, Pettersson T. Pleural fluid interferon-gamma and tumour necrosis factor-alpha in tuberculous and rheumatoid pleurisy. Eur Respir J 9:1652-5, 1996.
7. Oppenheim JJ, Ruscett i FW. Cytokines. In: Parslow TG, Stites DP, Terr AI, Imboden JB, editors. Medical Immunology. 10th ed. New York: Lange Medical Books/McGraw Hill Medical Publishing Division; pp. 157-9, 2001.
8. Barnes PF, Fong SJ, Brennan PJ, Twomey PE, Mazumder A, Modlin RL. Local production of tumor necrosis factor and interferon gamma in tuberculous pleuritis. J Immunol 145:149-54, 1990.
9. Ribera E, Ocaña I, Martinez-Vazquez JM, Rossell M, Español T, Ruibal A. High level of interferon gamma in tuberculous pleural effusion. Chest 93:308-11, 1998.
10. Villena V, López Encuentra A, Pozo F, Eschave Sustaeta J, Ortuño de Solo B, Estenoz Alfaro J, et al. Interferon gamma levels in pleural fluid for the diagnosis of tuberculosis. Am J Med 115:365-70, 2003.
11. Villena V, López Encuentra A, Echave Sustaeta J, Martin Escribano P, Ortuño de Solo B, Estenoz Alfaro J. Interferon-gamma in 388 immunocompromised and immunocompetent patients for diagnosing pleural tuberculosis. Eur Respir J 9:2635-9, 1996.
12. Greco S, Girardi E, Masciangelo R, Capoccetta GB, Saltini C. Adenosine deaminase and interferon gamma measurements for the diagnosis of tuberculous pleurisy. A meta-analysis. Int J Tuberc Lung Dis 7:777-86, 2003.
13. Sharma SK, Banga A. Diagnostic utility of pleural fluid interferon gamma in tuberculous pleural effusion. J Interferon Cytokine Res 24:213-7, 2004.
14. Sriram PS, Veena B, Antony MD, Kristin A. Pleural effusion. 47:1-3, 2007.
15. Krenke R, Safianowska A, Paplinska M, Nasilowski J, Dmowska-Sobstyl B, Bogacka-Zatorska E, et al. Pleural fluid adenosine deaminase and interferon gamma as diagnostic tools in tuberculous pleurisy. J Physiol Pharmacol 59(Suppl 6):349-60, 2008.
16. Krenke R, Korczyski P. Use of pleural fluid levels of adenosine deaminase and interferon gamma in the diagnosis of tuberculous pleuritis. Curr Opin Pulm Med 16:367-75, 2010.

Other articles written by the author Jayalakshmi Lingam
Otros artículos de Jayalakshmi Lingam

Jayalakshmi L, Ratnakumari G, Samson SH. Isolation, speciation and antifungal susceptibility testing of Candida from clinical specimens at a tertiary care hospital. Scholars Journal of Applied Medical Sciences (SJAMS) 2(6E):3193-3198, 2014.
Sirisha T, Jayalakshmi L, Ratnakumari G, Viswamitra P. Microbiological profile and their antimicrobial susceptibility in infective keratitis at regional eye hospital, Visakhapatnam. Scholars Journal of Applied Medical Sciences 3(3A):1083-1088, 2015.
Ratnakumari G, Jayalakshmi L, Sirisha T, Rajeswara RV, Jyothi PI. Etiological diagnosis and epidemiological characteristics of microbial keratitis at regional eye hospital, Visakhapatnam. Scholars Academic Journal of Biosciences (SAJB) 3(7):627-632, 2015
Rajeshwar RS, Lakshmi LJ, Pavani S, Kawle V, Prakash SJ. Bacteriological profile, antibiogram of burn wound isolates and detection of MRSA and ESBL production at tertiary care hospital, Hyderabad. World Journal of Pharmacy and Pharmaceutical Sciences 3(10):1691-1698, 2014.
Shailaja RM, Pavani S, Jayalakshmi L, Jaya Prakash RS. Onychomycosis, onycholysis in vitro susceptibility of isolates. Unique Journal of Medical and Dental Sciences 2(3):26 -29, 2014.
Chandrasekharnath N, Mahlakshmi YV, Jayalakshmi L, Venkanna B, Uma A. Screening and isolation of bioactive factors from Commiphora myrrha and evaluation of their antimicrobial activity. International Journal of Engineering Research and Applications 3(2):1291-1294, 2013.

SIIC System of Assisted Editing (SSEA)
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Jayalakshmi Lingam was invited by SIIC on
Jayalakshmi Lingam fue invitado por SIIC el
2013, july 15
  The authors' report was accepted on
La crónica del autor fue aprobada el
2018, december 8
The authors' report was accepted on
La crónica del autor fue aprobada el
2018, december 8
Published in siicsalud
Publicado en siicsalud
2019, march 8

The article is strictly related to the following sections of siicsalud
El artículo se relaciona estrictamente con las siguientes secciones de siicsalud

Infectious Diseases
/ Infectología
/ Inmunología

and secondarily related to the following sections

y secundariamente con las siguientes secciones

Clinical Chemistry
Diagnóstico por Laboratorio

Medical Education
Educación Médica

Information about the full text
Acerca del trabajo completo

Evaluation of Pleural Fluid Interferon Gamma as A Diagnostic Marker of Tuberculous Pleural Effusion

Author / Autor
Jayalakshmi Lingam1, Subhakar Kandi2

2 Doctor, Government General And Chest Hospital, Professor

Access to the original source
Journal of Dr. NTR University of Health Sciences

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