Alterations in regulators of the renal-bone axis, inflammation and iron status in older people with early renal impairment and the effect of vitamin D supplementation.

Alterations in regulators of the renal-bone axis, inflammation and iron status in older people with early renal impairment and the effect of vitamin D supplementation.

Fuente:Age and Ageing

Extracto: Alterations in regulators of the renal-bone axis, inflammation and iron status were found in early CKD. The response to vitamin D3 supplementation differed between eGFR groups. Plasma IL6 predicted both cFGF23 and iFGF23 and hepcidin predicted cFGF23.

Claves:fibroblast growth factor 23, inflammation markers, iron status, older people, renal impairment, vitamin D

Cita:Age Ageing 2024 May 1; 53 (5)

Autor/es:Christodoulou, Marilena (a)
Aspray, Terence J (b)

institución:(a) University of East Anglia, Norwich Medical School, Norwich, UK.
(b) Freeman Hospital, Bone Clinic, University of Newcastle upon Tyne, Newcastle upon Tyne, UK.

Conflicto:Terence J. Aspray has served on an advisory board and received lecture fees from Internis. William D. Fraser has received research grants, sat on advisory boards and given lectures on behalf of Eli Lilly, NPS Pharmaceuticals, Shirel, Entera Bio Ltd. and Nycomed. Inez Schoenmakers has served on advisory boards.

Formato:Informe impreso

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1093/ageing/afae096

Evidence from mendelian randomization identifies several causal relationships between primary membranous nephropathy and gut microbiota.

Evidence from mendelian randomization identifies several causal relationships between primary membranous nephropathy and gut microbiota.

Fuente:Renal Failure

Extracto: These findings lay the groundwork for future research exploring the interplay between pMN and the gut microbiota, with substantial implications for the prevention and treatment of pMN and its associated complications.

Claves:Gut microbiota, genome-wide association, mendelian randomization, primary membranous nephropathy

Cita:Ren Fail 2024 Dec; 46 (1) : 2349136.

Autor/es:Wu, Jianwei (a)
Zhang, Jing (b)

institución:(a) Department of Medical Technology, Gannan Healthcare Vocational College, Ganzhou, China.
(b) Department of Medical Technology, Gannan Healthcare Vocational College, Ganzhou, China.

Conflicto:No potential conflict of interest was reported by the author(s).

Formato:Informe impreso

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1080/0886022X.2024.2349136

Hepatic function markers as prognostic factors in patients with acute kidney injury undergoing continuous renal replacement therapy.

Fuente:Renal Failure

Extracto: Changes in hepatic function markers in acute renal failure may enable stratification of high-risk patients.

Claves:Acute kidney injury, De Ritis ratio, continuous renal replacement therapy, hepatic functional impairment, total bilirubin

Cita:Ren Fail 2024 Dec; 46 (1) : 2352127.

Autor/es:Nishino, Takuya (a)
Kubota, Yoshiaki (b)

institución:(a) Department of Health Care Administration, Nippon Medical School, Tokyo, Japan.
(b) Department of Cardiovascular Medicine, Nippon Medical School, Tokyo, Japan.

Conflicto:No potential conflict of interest was reported by the author(s).

Formato:Informe impreso

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1080/0886022X.2024.2352127

Predicting exacerbation of renal function by DNA methylation clock and DNA damage of urinary shedding cells: a pilot study.

Predicting exacerbation of renal function by DNA methylation clock and DNA damage of urinary shedding cells: a pilot study.

Fuente:Scientific Reports

Extracto: This study suggests the potential role of the DNA methylation clock and urinary DNA damage as predictive markers for the progression of chronic kidney disease.

Cita:Sci Rep 2024 May 21; 14 (1) : 11530.

Autor/es:Hishikawa, Akihito (a)
Nishimura, Erina Sugita (b)

institución:(a) Division of Nephrology, Endocrinology and Metabolism, Department of Internal Medicine, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-Ku, Tokyo, 160-8582, Japan. a-hishikawa@keio.jp.
(b) Division of Nephrology, Endocrinology and Metabolism, Department of Internal Medicine, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-Ku, Tokyo, 160-8582, Japan.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1038/s41598-024-62405-4

New sagittal abdominal diameter and transverse abdominal diameter based equations to estimate visceral fat area in type 2 diabetes patients.

New sagittal abdominal diameter and transverse abdominal diameter based equations to estimate visceral fat area in type 2 diabetes patients.

Fuente:Bmc Public Health

Extracto: In the T2D population, a VFA estimated equation is developed by incorporating SAD and TAD along with other measurement indices. This equation demonstrates a favorable estimated performance, suggesting to the development of novel and practical VFA estimation models in the future study.

Claves:Sagittal abdominal diameter (SAD), Transverse abdominal diameter (TAD), Type 2 diabetes, Visceral fat area (VFA)

Cita:BMC Public Health 2024 May 21; 24 (1) : 1364.

Autor/es:Li, Chao (a)
Zeng, Liankun (b)

institución:(a) Guangdong Medical University, Zhanjiang, 524001, China.
(b) Department of Endocrinology, the Fourth Affiliated Hospital of Guangzhou Medical University, Guangzhou, 511300, China.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1186/s12889-024-18659-8

Association between dietary behavior and puberty in girls.

Association between dietary behavior and puberty in girls.

Fuente:Bmc Pediatrics

Extracto: There were significant differences in dietary behaviors among girls with breast development with central priming and normal health girls with no breast development, and uterine body length was associated with an increasing risk of breast development with central priming among girls with breast development.

Claves:Children, Dietary behavior, Girls, Onset of puberty, Precocious puberty

Cita:BMC Pediatr 2024 May 21; 24 (1) : 349.

Autor/es:Du, Yiming (a)
Yan, Wu (b)

institución:(a) Department of Pediatrics, Zhongda Hospital, Southeast University, Nanjing, 210009, China.
(b) Department of Endocrinology, Children's Hospital of Nanjing Medical University, 72 Guangzhou Rd, Nanjing, 210008, China.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1186/s12887-024-04840-w

Lag effect of ambient temperature on respiratory emergency department visits in Beijing: a time series and pooled analysis.

Lag effect of ambient temperature on respiratory emergency department visits in Beijing: a time series and pooled analysis.

Fuente:Bmc Public Health

Tipo de trabajo:Metanálisis

Extracto: Temperature level, age-specific, and gender-specific effects between ambient temperature and the number of ED visits provide information on early warning measures for the prevention and control of respiratory diseases.

Claves:Ambient temperature, Distributed lag non-linear model, Emergency department visits, Meta-analysis, Meteorological factors, Respiratory diseases

Cita:BMC Public Health 2024 May 21; 24 (1) : 1363.

Autor/es:Li, Xuan (a)
Zhang, Yongming (b)

institución:(a) Department of Epidemiology and Biostatistics, School of Public Health, Tianjin Medical University, Heping District, Tianjin, 300070, P.R. China.
(b) Department of Pulmonary and Critical Care Medicine, Center of Respiratory Medicine, China-Japan Friendship Hospital, National Clinical Research Center for Respiratory Diseases, Beijing, China.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1186/s12889-024-18839-6

Association of the triglyceride-glucose index and its related parameters with frailty.

Association of the triglyceride-glucose index and its related parameters with frailty.

Fuente:Lipids in Health and Disease

Extracto: Elevated TyG and its associaed indices are associated with an increased prevalence of frailty. Reasonable control of blood glucose and blood lipids, and avoidance of obesity, may aid in reducing the occurrence of frailty in middle-aged and older adults.

Claves:Frailty, Triglyceride glucose-body mass index, Triglyceride glucose-waist to height ratio, Triglyceride glucose-wait circumference, Triglyceride-glucose

Cita:Lipids Health Dis 2024 May 21; 23 (1) : 150.

Autor/es:Yin, Huangyi (a)
Guo, Liuqing (b)

institución:(a) The First Affiliated Hospital of Guangxi Medical University, Nanning, China.
(b) The First Affiliated Hospital of Guangxi Medical University, Nanning, China.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1186/s12944-024-02147-4

Implementation research

Implementation research

Fuente:Trials

Tipo de trabajo:Estudio aleatorizado y controlado

Extracto: TRIAL REGISTRATION: NCT05944731 (Kenya), July 6, 2023; NCT05944718 (South Africa), July 13, 2023.

Claves:(3–10): glucose monitoring, CGM, Continuous glucose monitoring, Protocol, Randomised controlled trial, Standard of care, Type 1 diabetes

Cita:Trials 2024 May 21; 25 (1) : 331.

Autor/es:Marbán-Castro, Elena (a)
Muhwava, Lorrein (b)

institución:(a) FIND, Campus Biotech, Chemin Des Mines 9, 1202, Geneva, Switzerland. elena.marban@finddx.org.
(b) FIND, Campus Biotech, Chemin Des Mines 9, 1202, Geneva, Switzerland.

Conflicto:There are no competing interests to declare.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1186/s13063-024-08132-7

Telemedicine home-based management in patients with chronic heart failure and diabetes type II: study protocol for a randomized controlled trial.

Fuente:Trials

Tipo de trabajo:Estudio aleatorizado y controlado

Extracto: Registered on November 30, 2022.

Claves:6-min walk test, Diabetes mellitus type II, Heart failure, Motivational feedback, Randomized controlled trial, Tele-health, Teleassistance, Telemedicine, Telemonitoring, Telerehabilitation

Cita:Trials 2024 May 21; 25 (1) : 333.

Autor/es:Bernocchi, Palmira (a)
Giudici, Vittorio (b)

institución:(a) Continuity of Care Service, Istituti Clinici Scientifici Maugeri IRCCS, Institute of Lumezzane, Via G. Mazzini 129, 25065, Lumezzane, Brescia, Italy. palmira.bernocchi@icsmaugeri.it.
(b) Department of Cardiac Rehabilitation, Bolognini Hospital, Azienda Socio-Sanitaria Territoriale Bergamo Est, Seriate, Bergamo, Italy.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1186/s13063-024-08171-0

Ultra rapid lispro improves postprandial glucose control versus lispro in combination with basal insulin: a study based on CGM in type 2 diabetes in China.

Ultra rapid lispro improves postprandial glucose control versus lispro in combination with basal insulin: a study based on CGM in type 2 diabetes in China.

Fuente:Frontiers in Endocrinology

Extracto: URLi can control breakfast PPG better than insulin lispro in adults with T2D in China, while it is non-inferior in improving HbA1c. The incidence of hypoglycemic and weight gain were similar between the two groups.

Claves:HbA1c, continuous glucose monitoring, postprandial glucose, postprandial glucose excursions, ultra rapid lispro insulin

Cita:Front Endocrinol (Lausanne) 2024; 15 : 1364585.

Autor/es:Yuan, Lu (a)
Luo, Yi (b)

institución:(a) Department of Endocrinology, Nanjing First Hospital, Nanjing Medical University, Nanjing, China.
(b) Department of Endocrinology, Nanjing First Hospital, Nanjing Medical University, Nanjing, China.

Conflicto:The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3389/fendo.2024.1364585

Influence of nonalcoholic fatty liver disease severity on carotid adventitial vasa vasorum.

Fuente:Frontiers in Endocrinology

Extracto: These findings suggest that NASH severity doesn't independently drive early atherosclerosis or affects cIMT. Gender might play a role in early atherosclerotic disease in NAFLD, impacting VV density and cIMT. This highlights the need to consider other risk factors when evaluating cardiovascular risk in NAFLD patients.

Claves:atherosclerosis, nonalcoholic fatty liver disease, obesity, vasa vasorum, vascular disease

Cita:Front Endocrinol (Lausanne) 2024; 15 : 1366015.

Autor/es:León-Mengíbar, Josep (a)
Sánchez, Enric (b)

institución:(a) Endocrinology and Nutrition Department, University Hospital Arnau de Vilanova, Lleida, Spain.
(b) Obesity, Diabetes and Metabolism (ODIM) Research Group, Institut de Recerca Biomèdica de Lleida (IRBLleida), Lleida, Spain.

Conflicto:The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3389/fendo.2024.1366015

Treatment trajectories of gender incongruent Austrian youth seeking gender-affirming hormone therapy.

Fuente:Frontiers in Endocrinology

Tipo de trabajo:Revisión

Extracto: This is the first time that treatment trajectories, fertility preservation rates, and changes of legal gender marker have been described in Austrian adolescents with gender incongruence seeking GAMT. The majority received GAMT and changed their legal gender marker, while gender affirming surgery rates were low, and utilization of fertility preservation treatment options was rare.

Claves:fertility preservation, gender-affirming care, hormone therapy, legal gender marker, transgender

Cita:Front Endocrinol (Lausanne) 2024; 15 : 1258495.

Autor/es:Steininger, Jojo (a)
Knaus, Sarah (b)

institución:(a) Division of Pediatric Pulmonology, Allergology and Endocrinology, Department of Pediatrics and Adolescent Medicine, Medical University of Vienna, Vienna, Austria.
(b) Division of Gynecological Endocrinology and Reproductive Medicine, Department of Gynecology and Obstetrics, Medical University of Vienna, Vienna, Austria.

Conflicto:The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. The author(s) declared that they were an editorial board member of Frontiers, at the time of submission. This had no impact on the peer review process and the final decision.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3389/fendo.2024.1258495

Identification of Lipotoxicity-Related Biomarkers in Diabetic Nephropathy Based on Bioinformatic Analysis.

Identification of Lipotoxicity-Related Biomarkers in Diabetic Nephropathy Based on Bioinformatic Analysis.

Fuente:Journal of Diabetes Research

Extracto: Conclusion: The identified lipotoxicity-related hub genes provide a deeper understanding of the development mechanisms of DN, potentially offering new theoretical foundations for the development of diagnostic biomarkers and therapeutic targets related to lipotoxicity in DN.

Claves:bioinformatic analysis, biomarker, diabetic nephropathy, immune cell infiltration, lipotoxicity-related genes

Cita:J Diabetes Res 2024; 2024 : 5550812.

Autor/es:Nie, Han (a)
Yang, Huan (b)

institución:(a) Department of Endocrinology, Affiliated Hospital of Jiujiang University, No. 57, East Road, Xunyang District, Jiujiang, Jiangxi, China 332000.
(b) Department of Endocrinology, Affiliated Hospital of Jiujiang University, No. 57, East Road, Xunyang District, Jiujiang, Jiangxi, China 332000.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1155/2024/5550812

Clinical biomarkers for thyroid immune-related adverse events in patients with stage III and IV gastrointestinal tumors.

Clinical biomarkers for thyroid immune-related adverse events in patients with stage III and IV gastrointestinal tumors.

Fuente:Frontiers in Immunology

Extracto: Increased baseline level of ADA was associated with thyroid irAEs occurrence in patients with advanced gastrointestinal tumors who received ICI treatment. In the case of abnormal ADA, attention should be paid to the risk of thyroid irAEs.

Claves:adenosine deaminase, clinical biomarkers, immune related adverse events, programmed cell death protein 1 inhibitors, thyroid

Cita:Front Immunol 2024; 15 : 1381061.

Autor/es:Xing, Na (a)
Liu, Jing (b)

institución:(a) Department of Rheumatology and Immunology, The Fourth Hospital of Hebei Medical University, Shijiazhuang, China.
(b) Department of Endocrinology, The Fourth Hospital of Hebei Medical University, Shijiazhuang, China.

Conflicto:The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3389/fimmu.2024.1381061

Is it time to reduce the length of postgraduate training for physician-scientists in internal medicine?

Is it time to reduce the length of postgraduate training for physician-scientists in internal medicine?

Fuente:Jci Insight

Extracto: We propose that the time from medical school graduation to receipt of CDAs must be shortened to accelerate training and retention of physician-scientists.

Cita:JCI Insight 2024 May 22; 9 (10)

Autor/es:Gallagher, Emily Jane (a)
Conlin, Paul R (b)

institución:(a) Division of Endocrinology, Diabetes and Bone Disease, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
(b) VA Boston Healthcare System and Harvard Medical School, Boston, Massachusetts, USA.

Formato:Informe virtual

Idioma:Inglés

País de fuente:EE.UU.

Sitio web:http://dx.doi.org/10.1172/jci.insight.178214

LLL 44-1 Micronutrients in clinical nutrition: Trace elements.

LLL 44-1 Micronutrients in clinical nutrition: Trace elements.

Fuente:Clinical Nutrition Espen

Extracto: This text summarises the most relevant clinical manifestations of trace element depletion and deficiency, the difficulties in assessing status, and makes practical recommendations for provision for enteral and parenteral nutrition.

Claves:Copper, Deficiency, Inflammation, Iron, Monitoring, Selenium, Zinc

Cita:Clin Nutr ESPEN 2024 Jun; 61 : 369-376.

Autor/es:Shenkin, Alan (a)
Talwar, Dinesh (b)

institución:(a) Institute of Aging and Chronic Disease, University of Liverpool, Liverpool, UK. Electronic address: shenkin@liverpool.ac.uk.
(b) Scottish Trace Element and Micronutrient Diagnostic and Research Laboratory, Department of Clinical Biochemistry, Glasgow Royal Infirmary, Glasgow, UK. Electronic address: dinesh.talwar@ggc.scot.nhs.uk.

Conflicto:Declaration of competing interest None of the above authors declares any conflict.

Formato:Informe impreso

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1016/j.clnesp.2024.04.007

LLL 44 - 2 - Micronutrients in clinical nutrition: Vitamins.

Fuente:Clinical Nutrition Espen

Extracto: The text summarises the most relevant clinical manifestations of vitamins depletion and deficiency, the difficulties in assessing status, and makes recommendations for provision for medical nutrition therapy.

Claves:Ascorbic acid, Deficiency, Folic acid, Inflammation, Monitoring, Niacin, Thiamine, Vitamin D

Cita:Clin Nutr ESPEN 2024 Jun; 61 : 427-436.

Autor/es:Amrein, Karin (a)
de Man, Angélique M E (b)

institución:(a) Medical University of Graz, Department of Internal Medicine, Division of Endocrinology and Diabetology, Austria. Electronic address: karin.amrein@medunigraz.at.
(b) Amsterdam UMC, Location Vrije Universiteit, Department of Intensive Care, Amsterdam Cardiovascular Sciences, Amsterdam, the Netherlands. Electronic address: ame.deman@amsterdamumc.nl.

Conflicto:Declaration of competing interest None of the above authors declares any conflict.

Formato:Informe impreso

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1016/j.clnesp.2024.04.012

LLL 44-4 Micronutrients in acute disease and critical illness.

Fuente:Clinical Nutrition Espen

Extracto: Practical strategies are proposed.

Claves:Acute kidney injury, Heart failure, Immunity, Inflammation, Intestinal failure, Refeeding syndrome, Sepsis

Cita:Clin Nutr ESPEN 2024 Jun; 61 : 437-446.

Autor/es:de Man, Angélique M E (a)
Amrein, Karin (b)

institución:(a) Amsterdam UMC, Location Vrije Universiteit, Department of Intensive Care, Amsterdam Cardiovascular Sciences, Amsterdam, the Netherlands. Electronic address: ame.deman@amsterdamumc.nl.
(b) Medical University of Graz, Department of Internal Medicine, Division of Endocrinology and Diabetology, Austria. Electronic address: karin.amrein@medunigraz.at.

Conflicto:Declaration of competing interest None of the above authors declares any conflict.

Formato:Informe impreso

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1016/j.clnesp.2024.04.011

Serum levels of stem cell factor for predicting embryo quality.

Serum levels of stem cell factor for predicting embryo quality.

Fuente:Scientific Reports

Extracto: On oocyte retrieval day it was 33.47 (± 3.93) pg/ml and 52.23 (± 9.72) pg/ml (p < 0.05), respectively.

Claves:Assisted reproductive treatment, Controlled ovarian hyperstimulation, Embryo quality, Endometriosis, SCF, Stem cell factor

Cita:Sci Rep 2024 May 22; 14 (1) : 11689.

Autor/es:Liss, Joanna (a)
Kuczyńska, Martyna (b)

institución:(a) Research and Development Center, INVICTA, Polna 64, 81-740, Sopot, Poland.
(b) Department of Medical Biology and Genetics, University of Gdańsk, Gdańsk, Poland.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1038/s41598-024-61419-2