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Temporal alteration of serum bilirubin levels and its renoprotective effects in diabetic kidney disease: exploring the hormonal mechanisms.
Temporal alteration of serum bilirubin levels and its renoprotective effects in diabetic kidney disease: exploring the hormonal mechanisms.
Fuente:Frontiers in Endocrinology
Extracto:
The findings of this study suggest that the sustained
elevation of serum bilirubin concentration within the physiological range can
effectively retard the progression of Diabetic Kidney Disease (DKD). Furthermore,
the hormonal attributes of bilirubin may underlie its renoprotective effects.
institución:(a) Department of Nephrology and Endocrinology, Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing, China. (b) Department of Nephrology and Endocrinology, Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing, China.
Conflicto:The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
institución:(a) Division of Nephrology and Immunology, University of Alberta Faculty of Medicine & Dentistry, Edmonton, Alberta, Canada shamshad@ualberta.ca. (b) Division of Nephrology and Immunology, University of Alberta Faculty of Medicine & Dentistry, Edmonton, Alberta, Canada.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Preferred sources of information on diabetes prevention programmes: a population-based cross-sectional study in Poland.
Preferred sources of information on diabetes prevention programmes: a population-based cross-sectional study in Poland.
Fuente:Bmj Open
Extracto:
Communication on DM2
prevention should be adjusted to public preferences and expectations. Tailoring
interventions to different demographic groups can enhance outreach and
engagement. Email emerged as a popular choice, suggesting the potential of
digital communication in preventive health programmes.
Claves:diabetes & endocrinology, health education, preventive medicine
Cita:BMJ Open 2024 May 17; 14 (5) : e083362.
Autor/es:Grudziąż-Sękowska, Justyna (a) Sękowski, Kuba (b)
institución:(a) School of Public Health, Centrum Medyczne Ksztalcenia Podyplomowego, Warsaw, Poland jgrudziaz@cmkp.edu.pl. (b) School of Public Health, Centrum Medyczne Ksztalcenia Podyplomowego, Warsaw, Poland.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Feasibility and acceptability of a tailored health coaching intervention to improve type 2 diabetes self-management in Saudi Arabia: a mixed-methods randomised feasibility trial.
Feasibility and acceptability of a tailored health coaching intervention to improve type 2 diabetes self-management in Saudi Arabia: a mixed-methods randomised feasibility trial.
Fuente:Bmj Open
Tipo de trabajo:Estudio aleatorizado y controlado
Extracto:
The findings
demonstrated positive outcomes, supporting the need for a larger randomised
controlled trial to evaluate the efficacy of health coaching in improving
diabetes self-management among individuals with type 2 diabetes in Saudi Arabia.
Claves:Behavior, DIABETES & ENDOCRINOLOGY, PUBLIC HEALTH
Cita:BMJ Open 2024 May 17; 14 (5) : e078631.
Autor/es:Almulhim, Abdullah N (a) Alhowaish, Atheer (b)
institución:(a) School of Medicine and Population Health, The University of Sheffield, Sheffield, UK aalmulhim@seu.edu.sa. (b) Public Health Department, College of Health Sciences, Saudi Electronic University, Riyadh, 13316, Saudi Arabia.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Identification of high-performing antibodies for the reliable detection of Tau proteoforms by Western blotting and immunohistochemistry.
Identification of high-performing antibodies for the reliable detection of Tau proteoforms by Western blotting and immunohistochemistry.
Fuente:Acta Neuropathologica
Extracto:
This
work represents an extensive resource that will enable the re-interpretation of
published data, improve reproducibility in Tau research, and overall accelerate
scientific progress.
Claves:Antibody validation, Immunohistochemistry, Phosphorylation, Splice isoforms, Tau, Western blot
Cita:Acta Neuropathol 2024 May 18; 147 (1) : 87.
Autor/es:Ellis, Michael J (a) Lekka, Christiana (b)
institución:(a) JDRF/Wellcome Diabetes and Inflammation Laboratory, Nuffield Department of Medicine, Centre for Human Genetics, University of Oxford, Roosevelt Drive, Oxford, UK. (b) Islet Biology Group, Department of Clinical & Biomedical Sciences, Exeter Centre of Excellence in Diabetes (EXCEED), University of Exeter, RILD Building, Exeter, UK.
Conflicto:This work was partly funded by a collaborative agreement between the University of Oxford and UCB BioPharma. UCB staff were not involved in the design of the experiments, analysis of the data or interpretation of the results. The authors declare no other competing interests.
institución:(a) Institute for Diabetes Research and Metabolic Diseases (IDM) of the Helmholtz Center Munich at the University of Tübingen, Tübingen, Germany. Theresa.ester@med.uni-tuebingen.de. (b) Department of Internal Medicine, Division of Endocrinology, Diabetology and Nephrology, Eberhard Karls University Tübingen, Tübingen, Germany. Theresa.ester@med.uni-tuebingen.de.
Conflicto:GR is a co-founder and shareholder and works for Neuroelectrics, a company developing medical devices for NIBS. RS works for Neuroelectrics. Outside of the current work, MH reports research grants from Boehringer Ingelheim and Sanofi to the University Hospital of Tübingen, participation in advisory board for Boehringer Ingelheim, Sanofi and Amryt, and lecture fees from Amryt, Bayer, Sanofi, Eli Lilly,...
, Novartis, Novo Nordisk and Boehringer Ingelheim. TEN, KB, RV, CD, ALB, CP, HP and SK report no conflict of interest.
Design of a bi-directional methodology for automated assessment of compliance to continuous application of clinical guidelines, and its evaluation in the type 2 diabetes domain.
Design of a bi-directional methodology for automated assessment of compliance to continuous application of clinical guidelines, and its evaluation in the type 2 diabetes domain.
Fuente:Plos One
Extracto:
We
conclude that systems such as DiscovErr can effectively assess the quality of
continuous guideline-based care.
Cita:PLoS One 2024; 19 (5) : e0303542.
Autor/es:Hatsek, Avner (a) Hochberg, Irit (b)
institución:(a) Department of Software and Information Systems Engineering, Ben Gurion University, Beer Sheva, Israel. (b) Endocrinology, Diabetes, and Metabolism Institute, Rambam Health Care Campus, Haifa, Israel.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Transgender health objectives of training for adult Endocrinology and Metabolism programs: Outcomes of a modified-Delphi study.
Transgender health objectives of training for adult Endocrinology and Metabolism programs: Outcomes of a modified-Delphi study.
Fuente:Plos One
Tipo de trabajo:Consenso
Extracto:
To our knowledge, this is the first time a consensus-based approach
has been used to establish THOOT for any subspecialty postgraduate medicine
program across Canada or the United States. Our results lay the foundation
towards health equity and social justice in transgender health medical education,
offering a blueprint for future innovations.
institución:(a) Division of Endocrinology and Metabolism, Department of Medicine, University of Toronto, Toronto, ON, Canada. (b) Toronto Western Hospital, University Health Network, Toronto, ON, Canada.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
ABO and Rhesus blood groups and multiple health outcomes
ABO and Rhesus blood groups and multiple health outcomes
Fuente:Bmc Medicine
Tipo de trabajo:Revisión sistemática
Extracto:
Our findings suggest a potential relationship between ABO and
Rh blood groups and adverse health outcomes. Particularly the association between
blood group B and type 2 diabetes mellitus risk.
institución:(a) Department of Clinical Epidemiology, Shengjing Hospital of China Medical University, Shenyang, China. (b) Clinical Research Center, Shengjing Hospital of China Medical University, Shenyang, China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Hypopituitarism with secondary adrenocortical insufficiency and arginine vasopressin deficiency due to hypophysitis after COVID-19 vaccination
Hypopituitarism with secondary adrenocortical insufficiency and arginine vasopressin deficiency due to hypophysitis after COVID-19 vaccination
Fuente:Bmc Endocrine Disorders
Tipo de trabajo:Caso clínico
Extracto:
Herein, we report a rare case of anterior hypopituitarism and arginine
vasopressin deficiency secondary to hypophysitis following COVID-19 vaccination.
institución:(a) Department of Diabetes, Metabolism, and Endocrinology, Tokyo Metropolitan Institute for Geriatrics and Gerontology, 35-2 Sakaecho, Itabashi-Ku, Tokyo, 173-0015, Japan. (b) Department of Diabetes, Metabolism, and Endocrinology, Tokyo Metropolitan Institute for Geriatrics and Gerontology, 35-2 Sakaecho, Itabashi-Ku, Tokyo, 173-0015, Japan. tamurayo@tmghig.jp.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Association Between Insulin Resistance Indices and Liver Function Parameters Among Women With Polycystic Ovary Syndrome.
Association Between Insulin Resistance Indices and Liver Function Parameters Among Women With Polycystic Ovary Syndrome.
Fuente:Endocrinology, Diabetes & Metabolism
Extracto:
The highest tertile of TyG index and the TG/HDL-C
ratio as a surrogate of IR might play a role in detecting abnormalities of liver
function parameters among women. However, PCOS status cannot change the
association between IR and liver dysfunction.
Claves:insulin resistance, liver function tests, metabolic syndrome, polycystic ovary syndrome
institución:(a) Reproductive Endocrinology Research Center, Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran. (b) Reproductive Endocrinology Research Center, Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Conflicto:All authors declare no conflict of interest.
Breaking down barriers to bariatric care: a qualitative study on how telemedicine could transform patient experiences in a Swiss monocentric setting.
Breaking down barriers to bariatric care: a qualitative study on how telemedicine could transform patient experiences in a Swiss monocentric setting.
Fuente:Bmj Open
Extracto:
While telemedicine is increasingly accepted by the
public and provides accessible and cost-effective options for routine follow-up
appointments, there are still obstacles to overcome, such as a lack of physical
examination and technological limitations. However, integrating virtual
alternatives, like phone or video consultations, into routine bariatric
follow-ups could improve continuity and revolutionise bariatric care.
Claves:bariatric surgery, health informatics, qualitative research, telemedicine
Cita:BMJ Open 2024 May 20; 14 (5) : e083142.
Autor/es:Poljo, Adisa (a) Tynes, Deborah M (b)
institución:(a) Department of Visceral Surgery, Clarunis, University Digestive Health Care Center Basel, St. Claraspital and University Hospital Basel, Basel, Switzerland. (b) Clinic of Endocrinology, Diabetes and Metabolism, Department of Clinical Research, University Hospital Basel, Basel, Switzerland.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Prospective associations between breast feeding, metabolic health, inflammation and bone density in women with prior gestational diabetes mellitus.
Prospective associations between breast feeding, metabolic health, inflammation and bone density in women with prior gestational diabetes mellitus.
Fuente:Bmj Open Diabetes Research & Care
Extracto:
Longer breastfeeding duration among women with prior GDM was associated with
lower insulin resistance, weight, weight retention, body fat and inflammation,
but not lower bone density at 1 year postpartum. Breastfeeding for ≥6 months
after GDM can help to improve cardiometabolic health outcomes 1 year after
delivery.
Claves:Body Fat, Body Weight, Bone Density, GDM
Cita:BMJ Open Diabetes Res Care 2024 May 21; 12 (3)
Autor/es:Hebeisen, Ines (a) Gonzalez Rodriguez, Elena (b)
institución:(a) Obstetric Service, Department Woman-Mother-Child, Lausanne University Hospital, Lausanne, Switzerland. (b) University of Lausanne, Lausanne, Switzerland.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Association between being large for gestational age and cardiovascular metabolic health in children conceived from assisted reproductive technology
Association between being large for gestational age and cardiovascular metabolic health in children conceived from assisted reproductive technology
Fuente:Bmc Medicine
Tipo de trabajo:Estudio de cohortes
Extracto:
Compared to AGA, LGA children conceived from ART were associated with increased
cardiovascular-metabolic events, which appeared as early as infancy and with no
recovery by pre-puberty.
Claves:Assisted reproductive technology, Cardiovascular metabolic health, Large for gestational age, Obesity
Cita:BMC Med 2024 May 20; 22 (1) : 203.
Autor/es:Zhang, Yiyuan (a) Dai, Kexin (b)
institución:(a) Institute of Women, Children and Reproductive Health, Cheeloo College of Medicine, Shandong University, Shandong, 250012, China. (b) Institute of Women, Children and Reproductive Health, the Second Hospital, Cheeloo College of Medicine, Shandong University, Shandong, 250012, China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Unraveling genetic causality between metformin and myocardial infarction on the basis of Mendelian randomization.
Unraveling genetic causality between metformin and myocardial infarction on the basis of Mendelian randomization.
Fuente:Frontiers in Endocrinology
Extracto:
Metformin is not protective against the risk of myocardial
infarction in patients and may even be a risk factor for MI, old MI, acute MI,
and acute transmural MI of inferior wall.
institución:(a) Jiangsu Key Laboratory of New Drug Research and Clinical Pharmacy, Xuzhou Medical University, Xuzhou, China. (b) Department of Pharmacy, Affiliated Hospital of Jiangnan University, Wuxi, China.
Conflicto:The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
Evaluating the associations between compliance with CKD guideline component metrics and renal outcomes.
Evaluating the associations between compliance with CKD guideline component metrics and renal outcomes.
Fuente:Scientific Reports
Extracto:
Compliance to CKD guidelines in clinical practice is
significantly associated with improved renal outcomes, emphasizing the need for
guideline-concordant care in the management of CKD.
institución:(a) Noncommunicable Disease (NCD) Epidemiology Research Center, Shiga University of Medical Science, Otsu, Japan. (b) Noncommunicable Disease (NCD) Epidemiology Research Center, Shiga University of Medical Science, Otsu, Japan.
Conflicto:YY received grants or contracts from Daiichi-Sankyo, honoraria for lectures, presentations, speakers bureaus, manuscript writing or educational events from Torii, and Support for attending meetings from Bayer. JW received grants or contracts from Bayer, Chugai, Kyowa Kirin, Otsuka, Shionogi, Sumitomo, and Mitsubishi Tanabe, payment or honoraria for lectures, presentations, speakers bureaus, manuscript writing or educational events from Astra Zeneca, Bayer,...
Boehringer Ingelheim, Daiichi Sankyo, Kyowa Kirin, Novo Nordisk Pharma, and Mitsubishi Tanabe. TY is board member of Japanese Society of Nephrology (unpaid). IN received grants or contracts from Bayer Yakuhin, Terumo, Chugai Pharmaceutical, Kyowa Kirin, Daiichi-Sankyo, Sumitomo Pharma, Amicus Thepeuticus, Terumo, Kaneka, Otsuka Pharmaceutical, Astellas Pharma, and Ono Pharmaceutical, payment or honoraria for lectures, presentations, speakers bureaus, manuscript writing or educational events from AstraZeneca, Sanofi, Otsuka Pharmaceutical, Bayer, and Kyowa Kirin. KY received grants or contracts from Kyowa-Kirin and Tanabe-Mitsubishi, payment or honoraria for lectures, presentations, speakers bureaus, manuscript writing or educational events from Kyowa-Kirin and Tanabe-Mitsubishi, Mochida, Astra-Zeneca, and Asteras. and Otsuka. MN received grants or contracts from Kyowa-Kirin, Tanabe-Mitsubishi, Chugai, Boehringer Ingelheim, Torii, Takeda, Daiichi-Sankyo, and JT, consulting fees from Kyowa-Kirin, and Tanabe-Mitsubishi, payment or honoraria for lectures, presentations, speakers bureaus, manuscript writing or educational events from Kyowa-Kirin, Tanabe-Mitsubishi, Bayer, Astellas, JT, and Astra Zeneca. NK received consulting fees from Kyowa-Kirin and NovoNordisk Pharma, payment or honoraria for lectures, presentations, speakers bureaus, manuscript writing or educational events from Bayer Pharma, AstraZeneca, Ono Pharma, Novartis Phamak, Kyowa-Kirin, Boehringer Ingelheim Japan, Astellas Pharma, and Novo Nordisk Pharma, Participation on a Data Safety Monitoring Board or Advisory Board from Novo Nordisk Pharma and AstraZeneka, and board member of Japan Kidney Association. HO received grants or contracts from Kyowa Kirin, Torii Pharma, and Kissei Pharma, payment or honoraria for lectures, presentations, speakers bureaus, manuscript writing or educational events from Astellas, Kyowa Kirin, Daiichi Sankyo, AstraZeneca, Bayer AG, Mitsubishi Tanabe Pharma, Torii Pharma, Ono Pharma, Boehringer Ingelheim International GmbH, Participation on a Data Safety Monitoring Board or Advisory Board from Boehringer Ingelheim International GmbH, Daiichi Sankyo, Elli Lily, Mitsubishi Tanabe Pharma, Kissei Pharma, and board member of Japanese Society of Nephrology (unpaid).
Association of prediabetes with clinical outcomes in patients with chronic coronary syndrome: a post hoc analysis of the ISCHEMIA and ISCHEMIA-CKD trials.
Association of prediabetes with clinical outcomes in patients with chronic coronary syndrome: a post hoc analysis of the ISCHEMIA and ISCHEMIA-CKD trials.
Fuente:Cardiovascular Diabetology
Extracto:
In patients with chronic coronary syndrome, diabetes but not
prediabetes was associated with significantly increased risk of all-cause death
within a median follow-up period of 3.1 years. Trial Registration NCT01471522,
BioLINCC ID 13936.
Cita:Cardiovasc Diabetol 2024 May 20; 23 (1) : 176.
Autor/es:Jorda, Anselm (a) Hengstenberg, Christian (b)
institución:(a) Department of Clinical Pharmacology, Medical University of Vienna, Vienna, Austria. (b) Division of Cardiology, Department of Medicine II, Medical University of Vienna, Vienna, Austria.
Conflicto:None of the authors report conflict of interests relevant to this work.
Claves:behavior, frailty, hepatobiliary disease, protocols & guidelines, quality of life
Cita:BMJ Open 2024 May 21; 14 (5) : e083228.
Autor/es:Chen, Haiyan (a) Lu, Hanxiao (b)
institución:(a) Department of General Surgery, Affiliated Hospital of Jiangnan University, Wuxi, Jiangsu, China. (b) School of Medicine, Jiangnan University, Wuxi, Jiangsu, China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Effect of cytoplasmic fragmentation on embryo development, quality, and pregnancy outcome
Effect of cytoplasmic fragmentation on embryo development, quality, and pregnancy outcome
Fuente:Reproductive Biology and Endocrinology Rb&e
Tipo de trabajo:Revisión sistemática
Extracto:
This review highlights some of the challenges in analysis of fragmentation, while
revealing trends in our evolving knowledge of how fragmentation may relate to
functional development of the human embryos, implantation, and pregnancy outcome.
Claves:Embryo development, Fragmentation, Implantation, In vitro fertilization, Pregnancy outcome
Cita:Reprod Biol Endocrinol 2024 May 14; 22 (1) : 55.
Autor/es:Yazdani, Ariella (a) Halvaei, Iman (b)
institución:(a) Department of Obstetrics, Gynecology, and Reproductive Sciences, University of Vermont Medical Center, The Robert Larner College of Medicine at the University of Vermont, Burlington, VT, 05405, USA. (b) Present address: Obstetrics and Gynecology Institute, Cleveland Clinic Foundation, Cleveland, OH, 44195, USA.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
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