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Low ankle-brachial index is associated with higher cardiovascular mortality in individuals with nonalcoholic fatty liver disease.
Low ankle-brachial index is associated with higher cardiovascular mortality in individuals with nonalcoholic fatty liver disease.
Fuente:European Journal of Medical Research
Tipo de trabajo:Estudio de cohortes
Extracto:
Low ABI is independently
associated with higher cardiovascular mortality in NAFLD cases. This correlation
remains significant even in the absence of pre-existing cardiovascular disease or
diabetes.
institución:(a) Department of Geriatric Endocrinology and Metabolism, The First Affiliated Hospital of Guangxi Medical University, No. 6 Shuangyong Road, Nanning, 530021, Guangxi, China. (b) Department of Geriatric Endocrinology and Metabolism, The First Affiliated Hospital of Guangxi Medical University, No. 6 Shuangyong Road, Nanning, 530021, Guangxi, China.
Conflicto:The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
institución:(a) Lipid and Vascular Risk Unit, Department of Endocrinology and Nutrition, Hospital del Mar, 08003 Barcelona, Spain. (b) School of Medicine, Universitat Pompeu Fabra, 08003 Barcelona, Spain.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
A Cross-Sectional Study of Glomerular Hyperfiltration in Polycystic Ovary Syndrome.
A Cross-Sectional Study of Glomerular Hyperfiltration in Polycystic Ovary Syndrome.
Fuente:International Journal of Molecular Sciences
Extracto:
There were
progressive eGFR decrements for PCOS-nonGH, PCOS-GH, and PCOS-SGH in the
follow-up period which, in the presence of additional factors affecting renal
function, may be clinically important in the development of CKD in PCOS.
Autor/es:Butler, Alexandra E (a) Lubbad, Walaa (b)
institución:(a) Research Department, Royal College of Surgeons in Ireland Bahrain, Busaiteen, Adliya P.O. Box 15503, Bahrain. (b) Research Department, Royal College of Surgeons in Ireland Bahrain, Busaiteen, Adliya P.O. Box 15503, Bahrain.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
JMJD6 Autoantibodies as a Potential Biomarker for Inflammation-Related Diseases.
JMJD6 Autoantibodies as a Potential Biomarker for Inflammation-Related Diseases.
Fuente:International Journal of Molecular Sciences
Extracto:
Hence, JMJD6 autoantibodies may
reflect inflammation, thereby serving as a potential biomarker for diagnosing
specific inflammation-related diseases, including stroke, AMI, DM, and cancers,
and for prediction of the prognosis in patients with EC.
institución:(a) Department of Neurological Surgery, Graduate School of Medicine, Chiba University, Chiba 260-8670, Japan. (b) Department of Biochemistry and Genetics, Graduate School of Medicine, Chiba University, Chiba 260-8670, Japan.
Conflicto:This present study was performed in collaboration with Fujikura Kasei Co., Ltd., and Hideyuki Kuroda is an employee of Fujikura Kasei Co., Ltd. The other authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
Extracto:
This
consensus statement establishes a standardized approach to nutritional support,
aiming to optimize outcomes in pediatric cancer patients.
Claves:childhood cancer, nutrition, nutritional support
institución:(a) Department of Pediatrics, Pediatric Gastroenterology, Allergology and Nutrition, Medical University of Gdansk, 80-210 Gdansk, Poland. (b) Department of Pediatrics, Pediatric Gastroenterology, Allergology and Nutrition, Medical University of Gdansk, 80-210 Gdansk, Poland.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
The Impact of a Nutritional Intervention on Glycemic Control and Cardiovascular Risk Markers in Type 2 Diabetes.
The Impact of a Nutritional Intervention on Glycemic Control and Cardiovascular Risk Markers in Type 2 Diabetes.
Fuente:Nutrients
Tipo de trabajo:Estudio clínico
Extracto:
The individualized nutritional
intervention improved eating habits, anthropometric, biochemical, and
cardiovascular markers in T2D over 12 months, with sustained results during
follow-up. The dietary plan inspired by the Mediterranean and DASH diets
demonstrated good adaptation to the Brazilian food culture and the patients'
socioeconomic contexts. Consistent monitoring and personalized nutritional
management are essential for optimizing long-term outcomes. However, more
clinical trials are necessary in order to optimize the level of evidence for
longitudinal interventions.
institución:(a) Department of Hypertension, State Faculty of Medicine of São José do Rio Preto (FAMERP), São José do Rio Preto 15090-000, SP, Brazil. (b) Department of Hypertension, State Faculty of Medicine of São José do Rio Preto (FAMERP), São José do Rio Preto 15090-000, SP, Brazil.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Effects of Dietary Carbohydrate Concentration and Glycemic Index on Blood Glucose Variability and Free Fatty Acids in Individuals with Type 1 Diabetes.
Effects of Dietary Carbohydrate Concentration and Glycemic Index on Blood Glucose Variability and Free Fatty Acids in Individuals with Type 1 Diabetes.
Fuente:Nutrients
Extracto:
Different diets
may increase the risk of cardiovascular diseases by affecting GI, FFA, and blood
glucose levels.
institución:(a) Department of Nutrition and Dietetics, Faculty of Health Sciences, İstanbul Beykent University, Istanbul 34520, Turkey. (b) Institute of Health Sciences, Acibadem Mehmet Ali Aydınlar University, Istanbul 34450, Turkey.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Pubertal Timing Across Asian American, Native Hawaiian, and Pacific Islander Subgroups.
Pubertal Timing Across Asian American, Native Hawaiian, and Pacific Islander Subgroups.
Fuente:Jama Network Open
Tipo de trabajo:Estudio de cohortes
Extracto:
AND RELEVANCE: In this cohort
study of Asian American, Native Hawaiian, and Pacific Islander children and
adolescents, pubertal timing varied considerably across ethnic subgroups. Further
investigation is warranted to assess whether these differences contribute to
observed health disparities in adulthood, such as type 2 diabetes and
cardiovascular diseases.
Cita:JAMA Netw Open 2024 May 1; 7 (5) : e2410253.
Autor/es:Kubo, Ai (a) Acker, Julia (b)
institución:(a) Kaiser Permanente Division of Research, Oakland, California. (b) School of Public Health, University of California, Berkeley.
Conflicto:Conflict of Interest Disclosures: Dr Kubo reported receiving grants from the National Institute of Mental Health, National Institutes of Health (NIH), during the conduct of the study. Ms Aghaee reported receiving grants from the NIH during the conduct of the study. Dr Kushi reported receiving grants from the NIH during the conduct of the study. Dr Quesenberry reported receiving grants...
from the NIH during the conduct of the study. Dr Kanaya reported receiving grants from the NIH during the conduct of the study. Dr. Deardorff reported receiving grants from the NIH during the conduct of the study. No other disclosures were reported.
Medical science monitor international medical journal of experimental and clinical research
Selección SIIC: 16 Mayo, 2024
Medical science monitor international medical journal of experimental and clinical research
Tissue Inhibitors of Metalloproteinase 1 (TIMP-1) and 3 (TIMP-3) as New Markers of Acute Kidney Injury After Massive Burns.
Tissue Inhibitors of Metalloproteinase 1 (TIMP-1) and 3 (TIMP-3) as New Markers of Acute Kidney Injury After Massive Burns.
Fuente:Medical Science Monitor International Medical Journal of Experimental and Clinical Research
Extracto:
The evaluation of TIMPs in the early stage after burn injury has
potential benefits. The important roles of urine TIMP-1 and serum TIMP-3, as
novel markers of the risk of AKI development, were confirmed. Other parameters
require further analysis.
Cita:Med Sci Monit 2024 May 6; 30 : e943500.
Autor/es:Klimm, Wojciech (a) Szamotulska, Katarzyna (b)
institución:(a) Department of Internal Diseases, Nephrology and Dialysis, Military Institute of Medicine - National Research Institute, Warsaw, Poland. (b) Department of Epidemiology and Biostatistics, Institute of Mother and Child, Warsaw, Poland.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Identification and Economic Evaluation of Differentiated Thyroid Cancer Care Consumption Patterns Using Sequence Analysis.
Identification and Economic Evaluation of Differentiated Thyroid Cancer Care Consumption Patterns Using Sequence Analysis.
Fuente:International Journal of Public Health
Extracto:
Conclusion: The study underscores the increased
costs of managing DTC, shaped by consumption habits and socioeconomic position,
emphasising the need for more nuanced DTC management strategies.
institución:(a) Unité d'Evaluation Médico-Economique, Centre Hospitalier Universitaire de Toulouse, Toulouse, France. (b) Unité Mixte de Recherche1295 Centre d'Epidémiologie et de Recherche en Santé des Populations (CERPOP), Toulouse, France.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Extracto:
Further high-quality studies are needed to better
support the association between miR-21 and hypertension.
Claves:hypertension, meta-analysis, micro-RNA 21
Cita:Glob Heart 2024; 19 (1) : 41.
Autor/es:Xin, Caihong (a) He, Wei (b)
institución:(a) Department of Endocrinology and Metabolism, The Fourth People's Hospital of Shenyang, Shenyang, P.R. China. (b) Department of Endocrinology and Metabolism, People's Hospital of Liaoning Province, Shenyang, P.R. China.
Conflicto:The authors have no competing interests to declare.
British journal of hospital medicine (London, England 2005)
Selección SIIC: 16 Mayo, 2024
British journal of hospital medicine (London, England 2005)
General internal medicine: acquiring clinical acumen from bedside to front door with opportunities for undergraduate and postgraduate training.
General internal medicine: acquiring clinical acumen from bedside to front door with opportunities for undergraduate and postgraduate training.
Fuente:British Journal of Hospital Medicine (london, England 2005)
Extracto:
As we strive relentlessly while working on the ward at the bedside
and in acute portals, we ought to remind ourselves of what are the attractions of
general internal medicine and lead by example for the undergraduates and
postgraduate doctors in training who see us as role models for doing clinical
medicine, teaching, training and research.
Claves:Bed pressures, Discharges, General medicine, Medical registrar, Teaching, Training
Efficacy of multivitamin support following bariatric surgery in patients with obesity: a prospective observational study.
Efficacy of multivitamin support following bariatric surgery in patients with obesity: a prospective observational study.
Fuente:Eating and Weight Disorders Ewd
Tipo de trabajo:Estudio clínico
Extracto:
Following VSG or
RYGB, Bariatrifast administration was associated with normal values of essential
micronutrients, and it was well-tolerated without evidence of gastrointestinal
side effects. Clinical Trial Registration ClinicalTrials.gov, identifiers
NCT06152965.
institución:(a) Obesity and Lipodystrophy Center, Endocrinology Unit, University Hospital of Pisa, 56124, Pisa, Italy. (b) Obesity and Lipodystrophy Center, Endocrinology Unit, University Hospital of Pisa, 56124, Pisa, Italy.
Conflicto:J.V., R.J., V.A., C.L. have received reimbursement for attending symposia from BIOITALIA S.r.l. The other authors declare no conflict of interest. The sponsor had no role in the collection, analyses, or interpretation of data, and in writing the manuscript.
An interdisciplinary integrated specialized one-stop outpatient clinic for idiopathic intracranial hypertension - an assessment of sick leave, presenteeism, and health care utilization.
An interdisciplinary integrated specialized one-stop outpatient clinic for idiopathic intracranial hypertension - an assessment of sick leave, presenteeism, and health care utilization.
Fuente:The Journal of Headache and Pain
Tipo de trabajo:Estudio de cohortes
Extracto:
Interdisciplinary integrated management significantly
improves the burden of IIH in terms of sick leave, presenteeism and healthcare
consultations - particularly in socioeconomically underprivileged patient groups.
institución:(a) Department of Neurology, Medical University of Vienna, Waehringer Guertel 18-20, 1090, Vienna, Austria. gabriel.bsteh@meduniwien.ac.at. (b) Comprehensive Center for Clinical Neurosciences & Mental Health, Medical University of Vienna, Vienna, Austria. gabriel.bsteh@meduniwien.ac.at.
Conflicto:Gabriel Bsteh: has participated in meetings sponsored by, received speaker honoraria or travel funding from Biogen, Celgene/BMS, Lilly, Merck, Novartis, Roche, Sanofi-Genzyme and Teva, and received honoraria for consulting Biogen, Celgene/BMS, Merck, Novartis, Roche, Sanofi-Genzyme and Teva. He has received unrestricted research grants from Celgene/BMS and Novartis. Stefan Macher: declares no conflict of interest relevant to this study. Nik Krajnc:...
has participated in meetings sponsored by, received speaker honoraria or travel funding from Alexion, BMS/Celgene, Janssen-Cilag, Merck, Novartis, Roche and Sanofi-Genzyme and held a grant for a Multiple Sclerosis Clinical Training Fellowship Programme from the European Committee for Treatment and Research in Multiple Sclerosis (ECTRIMS). Wolfgang Marik: declares no conflict of interest relevant to this study. Martin Michl: declares no conflict of interest relevant to this study. Nina Müller: declares no conflict of interest relevant to this study. Sina Zaic: declares no conflict of interest relevant to this study. Jürgen Harreiter: declares no conflict of interest relevant to this study. Klaus Novak: declares no conflict of interest relevant to this study. Christian Wöber: has received honoraria consultancy/speaking from Apomedica, Curelator, Eli Lilly, Grünenthal, Hermes, Lundbeck, Novartis, Pfizer, Ratiopharm/Teva, and Stada. Berthold Pemp: has received honoraria for consultancy/speaking from Chiesi, GenSight, Novartis and Santen.
Ovarian response to controlled stimulation and its predictors in a limited-resource setting.
Ovarian response to controlled stimulation and its predictors in a limited-resource setting.
Fuente:Bmc Women's Health
Extracto:
Only two-thirds of our patients achieved a good ovarian
response. Induction duration, AMH concentration, and AFC were found to be
predictors, with the AFC being the strongest predictor. Therefore, the AFC should
be performed on all of our patients, and the AMH is selectively employed. Future
research must verify the best cutoff points and investigate additional factors
affecting ovarian response.
institución:(a) Department of Obstetrics and Gynecology, St.Paul's Hospital Millennium Medical College, Addis Ababa, Ethiopia. (b) Reproductive Endocrinology and Infertility, Department of Obstetrics and Gynecology, St.Paul's Hospital Millennium Medical College, Addis Ababa, Ethiopia.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Perceptions, attitudes, and behaviors among adolescents living with obesity, caregivers, and healthcare professionals in Italy: the ACTION Teens study.
Perceptions, attitudes, and behaviors among adolescents living with obesity, caregivers, and healthcare professionals in Italy: the ACTION Teens study.
Fuente:Eating and Weight Disorders Ewd
Extracto:
In
Italy, the impact of obesity on ALwO was underestimated by caregivers, and ALwO
and HCPs had different perceptions of key weight-loss motivators and barriers.
Additionally, the internet was a key information source for ALwO, which suggests
new education/communication strategies are needed. LEVEL OF EVIDENCE: IV;
Evidence obtained from multiple time series with/without intervention, e.g. TRIAL
REGISTRATION: ClinicalTrials.gov, NCT05013359.
Claves:Adolescents, Communication barriers, Obesity, Physician attitudes, Weight-loss motivators
Cita:Eat Weight Disord 2024 May 8; 29 (1) : 35.
Autor/es:Maffeis, Claudio (a) Busetto, Luca (b)
institución:(a) Department of Surgery, Dentistry, Gynecology and Pediatrics, Section of Pediatric Diabetes and Metabolism, University of Verona, Verona, Italy. claudio.maffeis@univr.it. (b) Department of Medicine, University of Padova, Padova, Italy.
Conflicto:Claudio Maffeis received consultancy fees from Novo Nordisk for his role as a member of the ACTION Teens Steering Committee during the conduct of the study; he also reports honoraria (for lectures) from Aboca, Eli Lilly, Novo Nordisk, Roche, and Sanofi, and participation in advisory boards for Abbott, Eli Lilly, Medtronic, and Sanofi outside the submitted work. Luca Busetto reports...
honoraria (for lectures) from PronoKal and Rhythm Pharmaceuticals, and participation in advisory boards for Bruno Farmaceutici, Eli Lilly, Novo Nordisk, and Pfizer outside the submitted work. Malgorzata Wasniewska is a consultant for Merck, Novo Nordisk, Pfizer, and Sandoz. Daniele Di Pauli and Andrea Lenzi have no relevant financial/non-financial interests to disclose. Carla Maccora is a permanent employee of Novo Nordisk.
Cancer control journal of the Moffitt Cancer Center
Selección SIIC: 16 Mayo, 2024
Cancer control journal of the Moffitt Cancer Center
Cancer Health Literacy and Its Correlated Factors in the United Arab Emirates-A Cross Sectional Study.
Cancer Health Literacy and Its Correlated Factors in the United Arab Emirates-A Cross Sectional Study.
Fuente:Cancer Control Journal of The Moffitt Cancer Center
Extracto:
CHL among the resident UAE population was moderately adequate, therefore
implementation of awareness campaigns seems to be warranted. Moreover, evaluation
research targeting the CHL impact on cancer prevention practices and screening is
also advocated.
Claves:United Arab Emirates, cancer health literacy, cancer screening, health literacy, knowledge
Cita:Cancer Control 2024 Jan-Dec; 31 : 10732748241248032.
Autor/es:Elbarazi, Iffat (a) Aziz, Faisal (b)
institución:(a) Institute of Public Health, College of Medicine and Health Science, United Arab Emirates University, Al Ain, United Arab Emirates. RINGGOLD: 11239 (b) Interdisciplinary Metabolic Medicine Trials Unit, Division of Endocrinology and Diabetology, Medical University of Graz, Graz, Austria. RINGGOLD: 31475
Conflicto:Declaration of Conflicting InterestsThe author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.
A High Fibrosis-4 Index is Associated with a Reduction in the Estimated Glomerular Filtration Rate in Non-obese Japanese Patients with Type 2 Diabetes Mellitus.
A High Fibrosis-4 Index is Associated with a Reduction in the Estimated Glomerular Filtration Rate in Non-obese Japanese Patients with Type 2 Diabetes Mellitus.
Fuente:The Kobe Journal of Medical Sciences
Extracto:
Our findings may enable
the more appropriate treatment of T2DM patients based on BMI level.
institución:(a) Clinical Laboratory, Nara Prefecture General Medical Center, Nara, Japan. (b) Division of Medical Chemistry, Department of Metabolism and Diseases, Kobe University Graduate School of Health Sciences, Kobe, Japan.
Comparative effectiveness of second line oral antidiabetic treatments among people with type 2 diabetes mellitus: emulation of a target trial using routinely collected health data.
Comparative effectiveness of second line oral antidiabetic treatments among people with type 2 diabetes mellitus: emulation of a target trial using routinely collected health data.
Fuente:Bmj (clinical Research Ed.)
Extracto:
This emulation study of a target trial found
that SGLT-2 inhibitors were more effective than sulfonylureas or DPP-4 inhibitors
in lowering mean HbA(1c), BMI, and systolic blood pressure and in reducing the
hazards of hospital admission for heart failure (v DPP-4 inhibitors) and kidney
disease progression (v sulfonylureas), with no evidence of differences in other
clinical endpoints.
Cita:BMJ 2024 May 8; 385 : e077097.
Autor/es:Bidulka, Patrick (a) Lugo-Palacios, David G (b)
institución:(a) Department of Non-Communicable Disease Epidemiology, London School of Hygiene and Tropical Medicine, London, WC1E 7HT, UK patrick.bidulka1@lshtm.ac.uk. (b) Department of Health Services Research and Policy, London School of Hygiene and Tropical Medicine, London, UK.
Conflicto:Competing interests: All authors have completed the ICMJE uniform disclosure form at www.icmje.org/disclosure-of-interest/ and declare: support from the National Institute for Health and Care Research (NIHR). AIA receives salary from the NIHR Biomedical Research Centre via the Oxford Centre for Diabetes, Endocrinology and Metabolism. AB is an economic advisor on the DiRECT trial, with ongoing responsibility for economic analysis during...
the long term follow-up phase. He serves as a consultant to Salutis Consulting on projects not related to diabetes. JWB has acted as a consultant to AstraZeneca, Bayer, Novartis, and Roche. DN is the UK Kidney Association Director of Informatics Research; she previously was involved in two GSK funded studies in sub-Saharan Africa unrelated to this work. PC sat on an NIHR Health Technology Assessment commissioning committee until September 2021. AHB has acted as consultant to several pharmaceutical companies within the past three years: AstraZeneca, Boehringer Ingelheim, Daiichi Sankyo, Eli Lilly, Gilead, Idorsia, Novo Nordisk, Rhythm, Roche, and Sanofi. IJD has unrestricted research grants from and shares in GSK and a research grant from AstraZeneca. KK has acted as a consultant and speaker or received grants for investigator initiated studies for AstraZeneca, Bayer, Novartis, Novo Nordisk, Sanofi-Aventis, Lilly and Merck Sharp and Dohme, Boehringer Ingelheim, Oramed Pharmaceuticals, Roche, and Applied Therapeutics.