Effect of immediate initiation of invasive ventilation on mortality in acute hypoxemic respiratory failure: a target trial emulation.

Fuente:Critical Care (london, England)

Extracto: The initiation of mechanical ventilation in patients with acute hypoxemic respiratory failure reduced the hazard of dying in this emulation of a target trial.

Claves:Artificial respiration, Critical care, Respiratory insufficiency

Cita:Crit Care 2024 May 10; 28 (1) : 157.

Autor/es:Mellado-Artigas, Ricard (a)
Borrat, Xavier (b)

institución:(a) Surgical Intensive Care Unit, Hospital Clínic de Barcelona, Barcelona, Spain. rmellado@clinic.cat.
(b) CIBER de Enfermedades Respiratorias (CIBERES), Instituto de Salud Carlos III, Madrid, Spain. rmellado@clinic.cat.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1186/s13054-024-04926-y

The Effects of Antofine on the Morphological and Physiological Characteristics of Phytophthora capsici.

Fuente:Molecules (basel, Switzerland)

Extracto: capsici.

Claves:Phytophthora capsici, antofine, biological characterization, mycelia morphology, respiratory chain complexes

Cita:Molecules 2024 Apr 25; 29 (9)

Autor/es:Wang, Mei (a)
Zhang, Weirong (b)

institución:(a) College of Life Science, Yulin University, Yulin 719000, China.
(b) College of Life Science, Yulin University, Yulin 719000, China.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3390/molecules29091965

In-Laboratory Polysomnography Worsens Obstructive Sleep Apnea by Changing Body Position Compared to Home Testing.

Fuente:Sensors (basel, Switzerland)

Extracto: The location of the sleep test seems to interfere with the evaluation of patients with more severe OSA.

Claves:apnea–hypopnea index, home sleep apnea testing, in-laboratory polysomnography, obstructive sleep apnea, supine decubitus

Cita:Sensors (Basel) 2024 Apr 27; 24 (9)

Autor/es:Teixeira, Raquel Chartuni Pereira (a)
Cahali, Michel Burihan (b)

institución:(a) Department of Otolaryngology, Hospital das Clínicas HCFMUSP, Faculdade de Medicina, Universidade de Sao Paulo, Av. Dr. Eneas de Carvalho Aguiar 255, sala 6167, São Paulo 05403-000, SP, Brazil.
(b) Department of Otolaryngology, Hospital das Clínicas HCFMUSP, Faculdade de Medicina, Universidade de Sao Paulo, Av. Dr. Eneas de Carvalho Aguiar 255, sala 6167, São Paulo 05403-000, SP, Brazil.

Conflicto:Raquel C. P. Teixeira owns a sleep lab in Belém, PA (Brazil). Michel B. Cahali is an investor at company Biologix—manufacturer of a home sleep test device in Brazil.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3390/s24092803

The Classification of VOCs Based on Sensor Images Using a Lightweight Neural Network for Lung Cancer Diagnosis.

Fuente:Sensors (basel, Switzerland)

Extracto: Compared to the existing CNN models, LTNet is more suitable for resource-limited POCT devices.

Claves:breath detection, cancer detection, convolutional neural network, lightweight neural network, sensor arrays

Cita:Sensors (Basel) 2024 Apr 28; 24 (9)

Autor/es:Zha, Chengyuan (a)
Li, Lei (b)

institución:(a) Department of Electronics and Electrical Engineering, Changchun University of Technology, Changchun 130012, China.
(b) Department of Electronics and Electrical Engineering, Changchun University of Technology, Changchun 130012, China.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3390/s24092818

DeepChestGNN: A Comprehensive Framework for Enhanced Lung Disease Identification through Advanced Graphical Deep Features.

Fuente:Sensors (basel, Switzerland)

Extracto: This study highlights the significant impact of combining advanced research with clinical application potential in diagnosing lung diseases, providing an optimal framework for precise and efficient disease identification and classification.

Claves:chest X-ray images, deep convolutional neural network, elastic deformation, feature extraction, graph neural network, image pre-processing, lung disease

Cita:Sensors (Basel) 2024 Apr 29; 24 (9)

Autor/es:Rana, Shakil (a)
Hosen, Md Jabed (b)

institución:(a) Health Informatics Research Laboratory (HIRL), Department of Computer Science and Engineering, Daffodil International University, Dhaka 1207, Bangladesh.
(b) Health Informatics Research Laboratory (HIRL), Department of Computer Science and Engineering, Daffodil International University, Dhaka 1207, Bangladesh.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3390/s24092830

Attention capture by own name decreases with speech compression.

Fuente:Cognitive Research: Principles and Implications

Extracto: Attention capture by time-compressed speech has practical significance and provides partial evidence for the duplex-mechanism account of auditory distraction.

Claves:Attention capture, Cocktail party effect, Time-compressed speech

Cita:Cogn Res Princ Implic 2024 May 12; 9 (1) : 29.

Autor/es:Li, Simon Y W (a)
Lee, Alan L F (b)

institución:(a) School of Psychological Science, The University of Western Australia, Perth, Australia. simon.li@uwa.edu.au.
(b) Department of Psychology, Lingnan University, Hong Kong SAR, China.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1186/s41235-024-00555-9

Current pharmacotherapies for advanced lung cancer with pre-existing interstitial lung disease A literature review and future perspectives.

Fuente:The Journal of Medical Investigation Jmi

Extracto: 71 : 9-22, February, 2024.

Claves:acute exacerbation, comorbidity, interstitial lung disease, lung cancer, pharmacotherapy

Cita:J Med Invest 2024; 71 (1.2) : 9-22.

Autor/es:Hanibuchi, Masaki (a)
Ogino, Hirokazu (b)

institución:(a) Department of Community Medicine for Respirology, Hematology, and Metabolism, Graduate School of Biomedical Sciences, Tokushima University, Tokushima, Japan.
(b) Department of Respiratory Medicine and Rheumatology, Graduate School of Biomedical Sciences, Tokushima University, Tokushima, Japan.

Formato:Informe impreso

Idioma:Inglés

País de fuente:Japón

Sitio web:http://dx.doi.org/10.2152/jmi.71.9

Intratracheal instillation of budesonide suspension versus normal saline on oxidative stress in neonates with meconium aspiration syndrome.

Fuente:The Journal of Maternal-fetal & Neonatal Medicine The Official Journal of The European Association of Perinatal Medicine, The Federation of Asia and Oceania Perinatal Societies, The International Society of Perinatal Obstetricians

Extracto: Intratracheal instillation of budesonide was shown to alleviate oxidative stress and shorten invasive ventilation time in neonates with MAS.

Claves:Meconium aspiration syndrome (MAS), budesonide, efficacy, intratracheal, mortality, oxidative stress

Cita:J Matern Fetal Neonatal Med 2024 Dec; 37 (1) : 2337708.

Autor/es:Qiu, Aijuan (a)
Wang, Jing (b)

institución:(a) Neonatology Department, Huai'an Maternal and Child Health Care Center, Huai'an, Jiangsu, P. R. China.
(b) Neonatology Department, Huai'an Maternal and Child Health Care Center, Huai'an, Jiangsu, P. R. China.

Formato:Informe impreso

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1080/14767058.2024.2337708

Expression of CD39 is associated with T cell exhaustion in ovarian cancer and its blockade reverts T cell dysfunction.

Fuente:Oncoimmunology

Extracto: Expression of CD39 on T cells was upregulated through CD3/CD28 stimulation and its blockade by a newly developed nanobody construct resulted in increased proliferation (eFluor), activation (CD25 and CD134), and production of cytotoxic cytokines (IFN-γ, TNF-α, and granzyme-B) of CD8(+) T cells.

Claves:Blockade, CD39, CD73, Nanobody, PD-1, TIGIT, malignant ascites, ovarian cancer

Cita:Oncoimmunology 2024; 13 (1) : 2346359.

Autor/es:Marius, Witt (a)
Leticia, Oliveira-Ferrer (b)

institución:(a) Department of Oncology, Hematology and Bone Marrow Transplantation with Section Pneumology, Hubertus Wald University Cancer Center, Hamburg, Germany.
(b) Department of Gynecology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:EE.UU.

Sitio web:http://dx.doi.org/10.1080/2162402X.2024.2346359

The Scope of Multimorbidity in Family Medicine: Identifying Age Patterns Across the Lifespan.

Fuente:Journal of The American Board of Family Medicine Jabfm

Tipo de trabajo:Estudio de cohortes

Extracto: The results from this study provide a comparison for the presence of multimorbidity within age cohorts longitudinally across the population. These patterns of comorbidity can assist in the allocation to practice resources that will best support the common conditions that patients need assistance with, especially as the patients transition between pediatric, adult, and geriatric care. Future work examining and comparing multimorbidity indices is warranted.

Claves:Adolescent Medicine, Aging, Comorbidity, Epidemiology, Family Medicine, Geriatrics, Lifespan, Multimorbidity, Pediatrics, Retrospective Studies

Cita:J Am Board Fam Med 2024 Mar-Apr; 37 (2) : 251-260.

Autor/es:Chartash, David (a)
Gilson, Aidan (b)

institución:(a) From the Section for Biomedical Informatics and Data Science, Yale University School of Medicine, New Haven, CT (DC, RAT), School of Medicine, University College Dublin - National University of Ireland, Dublin (DC), Department of Emergency Medicine, Yale University School of Medicine, New Haven, CT (AG, RAT), Primary Care Pediatrics, Nationwide Children's Hospital, Columbus, OH (LCH), Departments of Internal Medicine and Pediatrics, The Ohio State University School of Medicine, Columbus, OH (LCH).
(b) From the Section for Biomedical Informatics and Data Science, Yale University School of Medicine, New Haven, CT (DC, RAT), School of Medicine, University College Dublin - National University of Ireland, Dublin (DC), Department of Emergency Medicine, Yale University School of Medicine, New Haven, CT (AG, RAT), Primary Care Pediatrics, Nationwide Children's Hospital, Columbus, OH (LCH), Departments of Internal Medicine and Pediatrics, The Ohio State University School of Medicine, Columbus, OH (LCH).

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe impreso

Idioma:Inglés

País de fuente:EE.UU.

Sitio web:http://dx.doi.org/10.3122/jabfm.2023.230221R1

Clinician Barriers to Ordering Pulmonary Function Tests for Adults with Suspected Asthma.

Fuente:Journal of The American Board of Family Medicine Jabfm

Tipo de trabajo:Guía

Extracto: That in conjunction with an EHR prompt, which clinicians approved of, may lead to guideline congruent and improved quality in asthma care.

Claves:Asthma, Electronic Health Records, Family Medicine, Internal Medicine, Nurse Practitioners, Physician Assistants, Physicians, Primary Health Care, Pulmonary Function Tests, Quality of Care, Safety-Net Providers, Surveys and Questionnaires

Cita:J Am Board Fam Med 2024 Mar-Apr; 37 (2) : 321-323.

Autor/es:Haussmann, Alana (a)
Moudgal, Anita N (b)

institución:(a) From the University of Colorado School of Medicine, Aurora, CO (AM, MC, LH); Denver Health Medical Center, Denver, CO (LH); University of California Los Angeles David Geffen School of Medicine, Los Angeles, CA (AH).
(b) From the University of Colorado School of Medicine, Aurora, CO (AM, MC, LH); Denver Health Medical Center, Denver, CO (LH); University of California Los Angeles David Geffen School of Medicine, Los Angeles, CA (AH). anita.moudgal@cuanschutz.edu.

Conflicto:Conflict of interest: None.

Formato:Informe impreso

Idioma:Inglés

País de fuente:EE.UU.

Sitio web:http://dx.doi.org/10.3122/jabfm.2023.230347R1

Remission of chronic urticaria in patients treated with omalizumab.

Fuente:Acta Dermatovenerologica Alpina, Pannonica, Et Adriatica

Extracto: The study shows that a quarter of severe CSU patients achieve long-term remission. In addition, sgAHs effectively manage symptoms in a majority of relapsed cases, and those requiring omalizumab reintroduction respond favorably.

Cita:Acta Dermatovenerol Alp Pannonica Adriat 2024 May 14; 33 (2) : actaapa.2024.12.

Autor/es:Cvenkel, Klara (a)
Bizjak, Mojca (b)

institución:(a) Department of Dermatology, University Medical Center Ljubljana, Ljubljana, Slovenia.
(b) Golnik University Clinic of Respiratory and Allergic Diseases, Golnik, Slovenia.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Eslovenia

Sitio web:

Carbapenem-Resistant Pseudomonas aeruginosa Infection and Mixed Infections Are Risk Factors for Poor Outcome After Lung Transplant.

Fuente:Experimental and Clinical Transplantation Official Journal of The Middle East Society For Organ Transplantation

Extracto: Combined lower respiratory tract carbapenem-resistant P aeruginosa infection and P aeruginosa combined with bacterial infection early after lung transplant increased the risk of 30-day mortality after lung transplant.

Cita:Exp Clin Transplant 2024 Apr; 22 (4) : 300-306.

Autor/es:Wu, Yuhan (a)
Zhu, Jun (b)

institución:Wu, Yuhan (a)
Zhu, Jun (b)

Formato:Informe impreso

Idioma:Inglés

País de fuente:Turquía

Sitio web:http://dx.doi.org/10.6002/ect.2023.0268

A First Experience of Distant Lung Preservation for Transplantation in the Russian Federation.

Fuente:Experimental and Clinical Transplantation Official Journal of The Middle East Society For Organ Transplantation

Extracto: In conditions of shortages of donor organs, long-distance transportation is a reasonable, feasible, and safe procedure.

Cita:Exp Clin Transplant 2024 Apr; 22 (4) : 322-327.

Autor/es:Tarabrin, Evgeny A (a)
Saprin, Artem A (b)

institución:Tarabrin, Evgeny A (a)
Saprin, Artem A (b)

Formato:Informe impreso

Idioma:Inglés

País de fuente:Turquía

Sitio web:http://dx.doi.org/10.6002/ect.2024.0010

The effects of IL-27 and IL-35 gene variation and expression levels on the susceptibility and clinical manifestations of pulmonary tuberculosis.

The effects of IL-27 and IL-35 gene variation and expression levels on the susceptibility and clinical manifestations of pulmonary tuberculosis.

Fuente:Frontiers in Immunology

Extracto: Taken together, IL-35 gene variation might contribute to a protective role on the susceptibility to PTB, and IL-27 and IL-35 gene polymorphisms were associated with several clinical manifestations of patients with PTB.

Claves:IL-27, IL-35, infectious diseases, pulmonary tuberculosis, single-nucleotide polymorphisms

Cita:Front Immunol 2024; 15 : 1267624.

Autor/es:Gao, Lei (a)
Xiong, Yan-Jun (b)

institución:(a) Anhui Geriatric Institute, Department of Geriatric Respiratory and Critical Care Medicine, The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, China.
(b) Department of Tuberculosis, Anhui Chest Hospital, Hefei, Anhui, China.

Conflicto:The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3389/fimmu.2024.1267624

A machine learning model for the early diagnosis of bloodstream infection in patients admitted to the pediatric intensive care unit.

A machine learning model for the early diagnosis of bloodstream infection in patients admitted to the pediatric intensive care unit.

Fuente:Plos One

Extracto: Our model might help the medical team in clinical-decision making by creating an alert in the electronic medical record, which may allow early antimicrobial initiation and better outcomes.

Cita:PLoS One 2024; 19 (5) : e0299884.

Autor/es:Liporaci, Felipe (a)
Carlotti, Danilo (b)

institución:(a) Department of Pediatrics, Division of Pediatric Critical Care Medicine, Ribeirão Preto Medical School, University of São Paulo, São Paulo, Brazil.
(b) Institute of Mathematics and Statistics, University of São Paulo, São Paulo, Brazil.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:EE.UU.

Sitio web:http://dx.doi.org/10.1371/journal.pone.0299884

Assessment of Illness Severity in Adults Hospitalized With Acute Respiratory Tract Infection due to Influenza, Respiratory Syncytial Virus, or Human Metapneumovirus.

Assessment of Illness Severity in Adults Hospitalized With Acute Respiratory Tract Infection due to Influenza, Respiratory Syncytial Virus, or Human Metapneumovirus.

Fuente:Influenza and Other Respiratory Viruses

Extracto: These findings support the use of PROs (e.g., the RiiQ™) correlating with clinician assessments to gauge patient well-being and aid patient management by accurately assessing respiratory illness severity due to RSV, hMPV, or influenza.

Claves:HARTI, RSV, hMPV, hospitalization, human metapneumovirus, influenza, patient‐reported outcomes, respiratory syncytial virus

Cita:Influenza Other Respir Viruses 2024 May; 18 (5) : e13275.

Autor/es:Falsey, Ann R (a)
Walsh, Edward E (b)

institución:(a) Department of Medicine, University of Rochester, Rochester, New York, USA.
(b) Department of Medicine, University of Rochester, Rochester, New York, USA.

Conflicto:ARF has received research grants from Janssen, Merck Sharp & Dohme, Pfizer, BioFire Diagnostics, Moderna, Vax Co., and CyanVac; consulting fees from Sanofi Pasteur, ADMA Biologics, and Arrowhead; and personal fees for serving on a Data Safety Monitoring Board for Novavax. EEW received grants from Merck, Janssen, and Pfizer and was a paid member of the Data Safety and Monitoring... Board for GSK. SLH received advisory board consulting fees from Janssen Pharmaceuticals. YV is an employee of Janssen Research & Development. MS is a shareholder of Johnson & Johnson and former employee of Janssen Research & Development. EKHC is an employee of Janssen Global Services, LLC, and is a shareholder of Johnson & Johnson. GI is a shareholder of Johnson & Johnson and a former employee of Janssen Global Medical Affairs Infectious Diseases & Vaccines.

Formato:Informe impreso

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1111/irv.13275

Lack of racial and ethnic disparities in mortality in minority patients hospitalised with COVID-19 in a mid-Atlantic healthcare system.

Lack of racial and ethnic disparities in mortality in minority patients hospitalised with COVID-19 in a mid-Atlantic healthcare system.

Fuente:Bmj Open Respiratory Research

Extracto: However, there continues to remain a need for efforts to address the significant pre-existing race and ethnicity inequities highlighted by the COVID-19 pandemic to be better prepared for future public health emergencies.

Claves:COVID-19, Critical Care, Respiratory Infection, Viral infection

Cita:BMJ Open Respir Res 2024 May 1; 11 (1)

Autor/es:Galiatsatos, Panagis (a)
Garibaldi, Brian (b)

institución:(a) Johns Hopkins Medicine, Baltimore, Maryland, USA.
(b) Johns Hopkins Medicine, Baltimore, Maryland, USA.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1136/bmjresp-2024-002310

The Role of Human Mobility Flow in the Region-to-Region Spread of Respiratory Syncytial Virus Infection among Infants: An Infographic Analysis.

The Role of Human Mobility Flow in the Region-to-Region Spread of Respiratory Syncytial Virus Infection among Infants: An Infographic Analysis.

Fuente:Biological & Pharmaceutical Bulletin

Extracto: While social implementation of infection control measures has successfully suppressed the droplet-mediated respiratory infections, such as influenza, but not the airborne infections, it was suggested that the aerosol transmission and adult asymptomatic carrier were involved in the transmission of RSV akin to COVID-19.

Claves:human mobility flow, infection control measures, region-to-region spread, respiratory syncytial virus (RSV), social implementation, transmission mode

Cita:Biol Pharm Bull 2024; 47 (5) : 924-929.

Autor/es:Sasaki, Hide (a)
Seoka, Ryo (b)

institución:(a) Department of Microbiology and Infection Control, Faculty of Pharmacy, Osaka Medical and Pharmaceutical University.
(b) Department of Microbiology and Infection Control, Faculty of Pharmacy, Osaka Medical and Pharmaceutical University.

Formato:Informe impreso

Idioma:Inglés

País de fuente:Japón

Sitio web:http://dx.doi.org/10.1248/bpb.b23-00767

An eco-friendly and cost-effective HPTLC method for quantification of COVID-19 antiviral drug and co-administered medications in spiked human plasma.

An eco-friendly and cost-effective HPTLC method for quantification of COVID-19 antiviral drug and co-administered medications in spiked human plasma.

Fuente:Scientific Reports

Tipo de trabajo:Guía

Extracto: The method's greenness was assessed using Analytical Eco-scale, GAPI, and AGREE metrics.

Claves:COVID-19 antiviral, Remdesivir, Spiked human plasma, TLC, The method’s greenness

Cita:Sci Rep 2024 May 1; 14 (1) : 10025.

Autor/es:Ghozzy, Ekram A (a)
El-Enany, Nahed M (b)

institución:(a) Pharmaceutical Chemistry Department, Faculty of Pharmacy, Delta University for Science and Technology, Gamasa, 35712, Egypt.
(b) Pharmaceutical Analytical Chemistry Department, Faculty of Pharmacy, Mansoura University, Mansoura, 35516, Egypt.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1038/s41598-024-56923-4