Trends in Orthopaedic Surgery Workforce Diversity: Analyzing Changes Over Time.

Fuente:Journal of The American Academy of Orthopaedic Surgeons. Global Research & Reviews

Extracto: Small increases in surgeon population, female surgeons, and in some underrepresented minorities were seen.

Cita:J Am Acad Orthop Surg Glob Res Rev 2024 Apr 1; 8 (4)

Autor/es:Lum, Zachary C (a)
Dennison, Stanley (b)

institución:Lum, Zachary C (a)
Dennison, Stanley (b)

Conflicto:Each author certifies that he or she has no commercial associations (eg, consultancies, stock ownership, equity interest, patent/licensing arrangements, etc.) that might pose a conflict of interest in connection with the submitted article.

Formato:Informe virtual

Idioma:Inglés

País de fuente:EE.UU.

Sitio web:

Incidence and prevalence of musculoskeletal health conditions in survivors of childhood and adolescent cancers: A report from the Swiss childhood cancer survivor study.

Fuente:Cancer Medicine

Extracto: MSHCs are prevalent in survivors, the risk is increasing in younger survivor cohorts, and MSHCs usually occur in multimorbid survivors. Strengthening of rehabilitation services and appropriate referrals are needed to mitigate the effects of the cancer and cancer treatment.

Claves:Switzerland, childhood cancer, musculoskeletal health conditions, registry, scoliosis, survivors

Cita:Cancer Med 2024 Apr; 13 (8) : e7204.

Autor/es:Christen, Salome (a)
Roser, Katharina (b)

institución:(a) Faculty of Health Sciences and Medicine, University of Lucerne, Lucerne, Switzerland.
(b) Faculty of Health Sciences and Medicine, University of Lucerne, Lucerne, Switzerland.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe impreso

Idioma:Inglés

País de fuente:EE.UU.

Sitio web:http://dx.doi.org/10.1002/cam4.7204

Association between hepatitis A seropositivity and bone mineral density in adolescents and adults: a cross-sectional study using NHANES data.

Fuente:Sao Paulo Medical Journal = Revista Paulista de Medicina

Extracto: This study confirmed that both adolescent and adult individuals seropositive for Hepatitis A antibodies had reduced BMD among both adolescents and adults, especially in the adult group. This finding suggests a possible link between Hepatitis A infection and risk of osteoporosis.

Cita:Sao Paulo Med J 2024; 142 (5) : e2023266.

Autor/es:Yu, Zhuowen (a)
Hu, Gunchu (b)

institución:(a) Doctoral student, Physician. Department of Orthopedics, Second Xiangya Hospital of Central South University, Changsha, China; Hunan Key Laboratory of Tumor Models and Individualized Medicine, Second Xiangya Hospital of Central South University, Changsha, China.
(b) Doctoral student, Physician. Department of General Surgery, Second Xiangya Hospital of Central South University, Changsha, China.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Brasil

Sitio web:http://dx.doi.org/10.1590/1516-3180.2023.0266.R1.08022024

Expression and Impact of Fibronectin, Tenascin-C, Osteopontin, and Type XIV Collagen in Fuchs Endothelial Corneal Dystrophy.

Fuente:Investigative Ophthalmology & Visual Science

Extracto: This study highlights new abnormal ECM components in FECD, suggests a certain chronology in their deposition, and demonstrates their impact on cell behavior.

Cita:Invest Ophthalmol Vis Sci 2024 Apr 1; 65 (4) : 38.

Autor/es:Tchatchouang, Ange (a)
Brunette, Isabelle (b)

institución:(a) Centre de recherche du CHU de Québec-Université Laval, axe médecine régénératrice, Québec, Québec, Canada.
(b) Département d'ophtalmologie et d'ORL-CCF, Faculté de médecine, Université Laval, Québec, Québec, Canada.

Conflicto:Disclosure: A. Tchatchouang, None; I. Brunette, None; P.J. Rochette, None; S. Proulx, None

Formato:Informe impreso

Idioma:Inglés

País de fuente:EE.UU.

Sitio web:http://dx.doi.org/10.1167/iovs.65.4.38

tRNA anticodon cleavage by target-activated CRISPR-Cas13a effector.

Fuente:Science Advances

Extracto: The mechanism of Cas13a-induced antiphage defense resembles that of bacterial anticodon nucleases, which is compatible with the hypothesis that type VI effectors evolved from an abortive infection module encompassing an anticodon nuclease.

Cita:Sci Adv 2024 Apr 26; 10 (17) : eadl0164.

Autor/es:Jain, Ishita (a)
Kolesnik, Matvey (b)

institución:(a) Waksman Institute for Microbiology, Rutgers, The State University of New Jersey, Piscataway, NJ, USA.
(b) Center for Molecular and Cellular Biology, Skolkovo Institute of Science and Technology, Moscow, Russia.

Formato:Informe impreso

Idioma:Inglés

País de fuente:EE.UU.

Sitio web:http://dx.doi.org/10.1126/sciadv.adl0164

Effects of risk factors on the development and mortality of early- and late-onset dementia

Fuente:Alzheimer's Research & Therapy

Tipo de trabajo:Estudio de cohortes

Extracto: Risk factors influencing dementia development and mortality differed in EOD and LOD. Targeted public health interventions addressing age-related risk factors may reduce dementia incidence and mortality.

Claves:Dementia, Development, Mortality, Onset age, Population study, Risk factor

Cita:Alzheimers Res Ther 2024 Apr 25; 16 (1) : 92.

Autor/es:Chun, Min Young (a)
Chae, Wonjeong (b)

institución:(a) Department of Neurology, Samsung Medical Center, Sungkyunkwan University School of Medicine, 81 Irwon-ro, Gangnam-gu, Seoul, 06351, South Korea.
(b) Department of Neurology, Yonsei University College of Medicine, 50-1, Yonsei-Ro, Seodaemun-gu, Seoul, 03722, South Korea.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1186/s13195-024-01436-5

Classification of Osteophytes Occurring in the Lumbar Intervertebral Foramen.

Fuente:Tomography (ann Arbor, Mich.)

Extracto: The findings show that osteophytic extrusions, which alter the natural anatomical structure of the lumbar intervertebral foramina, are common and can narrow the foramen.

Claves:foraminal stenosis, lumbar intervertebral foramen, osteophyte

Cita:Tomography 2024 Apr 19; 10 (4) : 618-631.

Autor/es:Taçyıldız, Abdullah Emre (a)
İnceoğlu, Feyza (b)

institución:(a) Department of Neurosurgery, Faculty of Medicine, Turgut Özal University, Malatya 44090, Turkey.
(b) Department of Neurosurgery, Faculty of Medicine, Karabuk University, Karabuk 78200, Turkey.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3390/tomography10040047

Amorphous calcium carbonate enhances osteogenic differentiation and myotube formation of human bone marrow derived mesenchymal stem cells and primary skeletal muscle cells under microgravity conditions.

Fuente:Life Sciences in Space Research

Extracto: The results, combined with previous data, support the use of ACC as an advantageous supplement for preventing muscle and bone deterioration in outer space conditions, facilitating extended extraterrestrial voyages and colonization.

Claves:Amorphous calcium carbonate (ACC), International Space Station (ISS), Microgravity, Muscle cells, Nanoparticles, Osteoblasts

Cita:Life Sci Space Res (Amst) 2024 May; 41 : 146-157.

Autor/es:Ecker Cohen, Orit (a)
Neuman, Sara (b)

institución:(a) Amorphical LTD, 11 HaHarash St. Nes Ziona, 740318, Israel.
(b) Amorphical LTD, 11 HaHarash St. Nes Ziona, 740318, Israel.

Conflicto:Declaration of competing interest The authors declare the following financial interests/personal relationships which may be considered as potential competing interests: Yigal Blum, Sara Neuman, Yehudit Natan and Yosef Ben are employees or contractors of Amorphical Israel. Orit Ecker Cohen was employed at Amorphical, at the time of the described experiments. Yigal Blum and Yosef Ben are shareholders at Amorphical. Almog... Levy, Danny Bavli, and Shimon Amselem are employees of SpacePharma R&D Israel.

Formato:Informe impreso

Idioma:Inglés

País de fuente:Países Bajos

Sitio web:http://dx.doi.org/10.1016/j.lssr.2024.02.007

Retrospective Cohort Study of Early versus Delayed Ballon Kyphoplasty Intervention for Osteoporotic Vertebral Fracture Treatment.

Fuente:Medicina (kaunas, Lithuania)

Tipo de trabajo:Estudio de cohortes

Extracto: Conclusions/Level of Evidence: Early BKP for OVF treatment may achieve better outcomes and fewer adjacent segmental fractures than delayed intervention.

Claves:ballon kyphoplasty, kyphosis, osteoporotic vertebral fractures

Cita:Medicina (Kaunas) 2024 Mar 22; 60 (4)

Autor/es:Miyamoto, Akiyoshi (a)
Parihar, Umesh (b)

institución:(a) Department of Orthopaedic Surgery, Okayama Rosai Hospital, Okayama 702-8055, Japan.
(b) Department of Orthopaedic Surgery, Okayama Rosai Hospital, Okayama 702-8055, Japan.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3390/medicina60040519

Treatment of Osteoporosis in Men on Androgen Deprivation Therapy in Japan.

Fuente:Medicina (kaunas, Lithuania)

Extracto: BP and denosumab were found to be very effective in increasing BMD.

Claves:androgen deprivation therapy, osteoporosis, treatment

Cita:Medicina (Kaunas) 2024 Mar 28; 60 (4)

Autor/es:Nishimoto, Hanako (a)
Inui, Atsuyuki (b)

institución:(a) Department of Orthopaedic Surgery, Kobe University Graduate School of Medicine, Kobe 650-0017, Japan.
(b) Department of Orthopaedic Surgery, Kobe University Graduate School of Medicine, Kobe 650-0017, Japan.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3390/medicina60040551

Hip Fractures in Elderly Individuals Did Not Decrease during the Coronavirus Disease 2019 Pandemic: Insights from the 2015 and 2020 Niigata Prefecture Fragility Hip Fracture Surveys.

Fuente:Medicina (kaunas, Lithuania)

Extracto: Considering that the number of fragility fractures remains the same during an infectious disease pandemic such as COVID-19, it is necessary to ensure that healthcare resources are available to deal with them.

Claves:COVID-19, Niigata Prefecture, hip fracture, older adults

Cita:Medicina (Kaunas) 2024 Mar 30; 60 (4)

Autor/es:Nozaki, Asami (a)
Imai, Norio (b)

institución:(a) Division of Orthopedic Surgery, Department of Regenerative and Transplant Medicine, Niigata University Graduate School of Medical and Dental Sciences, 1-754, Asahimachi-Dori, Chuo-Ku, Niigata City 951-8510, Niigata Prefecture, Japan.
(b) Department of Orthopedic Surgery, Niigata Tsubame Rosai Hospital, Sado 636, Tsubame City 959-1228, Niigata Prefecture, Japan.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3390/medicina60040573

Cutaneous Crohn disease presenting as "knife-edged" ulcers

Fuente:Wounds a Compendium of Clinical Research and Practice

Tipo de trabajo:Caso clínico

Extracto: This case supports the inclusion of CCD in the differential diagnosis in patients with knife-edged granulomatous skin lesions in intertriginous locations. This clinical condition may present in the setting of no or limited GI symptoms. The management of CCD and a proposed treatment algorithm are also presented.

Cita:Wounds 2024 Mar; 36 (3) : 84-89.

Autor/es:Nickles, Melissa A (a)
Karimi, Saman S (b)

institución:(a) Department of Dermatology, University of Illinois at Chicago, Chicago, IL.
(b) Department of Pathology, University of Illinois at Chicago, Chicago, IL.

Formato:Informe impreso

Idioma:Inglés

País de fuente:EE.UU.

Sitio web:http://dx.doi.org/10.25270/wnds/23157

Analyzing diversity, equity, and inclusion content on dermatology fellowship program websites.

Fuente:Medical Education Online

Extracto: The results of this study reveal an overall lack of DEI content across all dermatology subspecialties' webpages and represent an actionable area of improvement for fellowship directors to increase their DEI efforts to attract a diverse pool of applicants to their program.

Claves:DEI, Diversity, equity, and inclusion, dermatology, graduate medical education, program websites

Cita:Med Educ Online 2024 Dec 31; 29 (1) : 2347762.

Autor/es:Bohler, Forrest (a)
Garden, Allison (b)

institución:(a) Medical Student, Oakland University William Beaumont School of Medicine, Rochester, MI, USA.
(b) Medical Student, Edward Via College of Osteopathic Medicine - Carolinas Campus, Spartanburg, SC, USA.

Conflicto:No potential conflict of interest was reported by the author(s).

Formato:Informe impreso

Idioma:Inglés

País de fuente:EE.UU.

Sitio web:http://dx.doi.org/10.1080/10872981.2024.2347762

An acute phase reaction from zoledronate mimicking symptoms seen in opioid withdrawal

Fuente:Addiction Science & Clinical Practice

Tipo de trabajo:Caso clínico

Extracto: Zoledronate, well known for causing acute phase reactions, was likely the cause of withdrawal-like symptoms. Acute phase reactions with bisphosphonates mostly occur in the first infusion, and the incidence decreases with subsequent infusions. Symptoms typically occur 24-72 h post-infusion, and last at most for 72 h. Cognitive bias led the primary team to be concerned with opioid withdrawal rather than investigating other causes for the patient's presentation. Therefore, providers should thoroughly investigate potential etiologies and rule them out accordingly to provide the best care. Health care providers should also be aware of the implicit biases that potentially impact the quality of care they provide to patients.

Claves:Acute pain, Addiction medicine, Cognitive bias, Pain medicine, Zoledronic acid

Cita:Addict Sci Clin Pract 2024 May 1; 19 (1) : 34.

Autor/es:Acharya, Pankti P (a)
Joseph, Crystal (b)

institución:(a) Department of Anesthesiology, Robert Wood Johnson University Hospital, New Brunswick, NJ, USA. acharya.pankti@gmail.com.
(b) Department of Anesthesiology, Beth Israel Deaconess Medical Center, Boston, MA, USA.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1186/s13722-024-00464-8

A phase I/II study of nintedanib and capecitabine for refractory metastatic colorectal cancer.

Fuente:Jnci Cancer Spectrum

Extracto: The combination of nintedanib and capecitabine is well tolerated. Clinical efficacy appears to be superior to regorafenib or tipiracil hydrochloride monotherapy. Further investigation of similar combinations is warranted. CLINICALTRIALS.GOV IDENTIFIER: NCT02393755.

Cita:JNCI Cancer Spectr 2024 Apr 30; 8 (3)

Autor/es:Boland, Patrick M (a)
Ebos, John M L (b)

institución:(a) Department of Medical Oncology, Rutgers Cancer Institute of New Jersey, New Brunswick, NJ, USA.
(b) Department of Medicine, Roswell Park Comprehensive Cancer Center, Buffalo, NY, USA.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe impreso

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1093/jncics/pkae017

Euthanasia and Physician-Assisted Suicide in People With an Accumulation of Health Problems Related to Old Age: A Cross-Sectional Questionnaire Study Among Physicians in the Netherlands.

Fuente:International Journal of Public Health

Extracto: Conclusion: Enhanced understanding of people with an accumulation of health problems related to old age requesting EAS can contribute to the ongoing debate on the permissibility of EAS in people without life-threatening conditions.

Claves:accumulation of health problems related to old age, end-of-life care, euthanasia, medical decision-making, physician-assisted suicide

Cita:Int J Public Health 2024; 69 : 1606962.

Autor/es:Kraak-Steenken, Frédérique W M (a)
Renckens, Sophie C (b)

institución:(a) Department of Public and Occupational Health, Amsterdam Public Health Research Institute, VU Medical Center, Amsterdam, Netherlands.
(b) Expertise Center for Palliative Care Amsterdam UMC, Amsterdam, Netherlands.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3389/ijph.2024.1606962

Osteostatin, a peptide for the future treatment of musculoskeletal diseases.

Osteostatin, a peptide for the future treatment of musculoskeletal diseases.

Fuente:Biochemical Pharmacology

Extracto: Our aim with this work is to review the Osteostatin main features, the knowledge of its mechanisms of action as well as its possible use for the treatment of osteoporosis, bone regeneration and fractures and against arthritis given its anti-inflammatory properties.

Claves:Aging, Bone anabolism, Fracture, Osteoporosis, Osteostatin, PTHrP

Cita:Biochem Pharmacol 2024 May; 223 : 116177.

Autor/es:Lozano, Daniel (a)
Gortazar, Arancha R (b)

institución:(a) Departamento de Química en Ciencias Farmacéuticas, Facultad de Farmacia, Universidad Complutense de Madrid, Instituto de Investigación Hospital 12 de Octubre (i+12), Plaza de Ramón y Cajal s/n, 28040 Madrid, Spain; Centro de Investigación Biomédica en Red de Bioingeniería, Biomateriales y Nanomedicina (CIBER-BBN), 28029 Madrid, Spain.
(b) Grupo de Fisiopatología Ósea, Departamento de Ciencias Médicas Básicas, Instituto de Medicina Aplicada de la Universidad San Pablo-CEU, Facultad de Medicina, Universidad San Pablo CEU, CEU Universities, Urbanización Montepríncipe s/n, 28925 Madrid, Spain.

Conflicto:Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

Formato:Informe impreso

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1016/j.bcp.2024.116177

The effect of Schizophyllan on the differentiation of osteoclasts and osteoblasts.

The effect of Schizophyllan on the differentiation of osteoclasts and osteoblasts.

Fuente:Biochemical and Biophysical Research Communications

Extracto: Thus, SPG could be a therapeutic agent for bone resorption-related diseases such as osteoporosis, rheumatoid arthritis, and periodontitis.

Claves:Differentiation, Osteoblast, Osteoclast, Schizophyllan, β-glucan

Cita:Biochem Biophys Res Commun 2024 May 28; 710 : 149860.

Autor/es:Kim, Soo-Ho (a)
Park, Keun Ha (b)

institución:(a) Department of Dentistry, Chungnam National University Hospital, 282 Munhwa-ro, Jung-gu, Daejeon, 35015, Republic of Korea; Department of Molecular Genetics, School of Dentistry and Dental Research Institute, Seoul National University, Seoul, 08826, Republic of Korea.
(b) Department of Oral Microbiology and Immunology, College of Dentistry, Wonkwang University, Iksan, Jeonbuk, 54538, Republic of Korea.

Conflicto:Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

Formato:Informe impreso

Idioma:Inglés

País de fuente:EE.UU.

Sitio web:http://dx.doi.org/10.1016/j.bbrc.2024.149860

Radiological manifestations and clinical findings of patients with oncologic and osteoporotic medication-related osteonecrosis of the jaw.

Radiological manifestations and clinical findings of patients with oncologic and osteoporotic medication-related osteonecrosis of the jaw.

Fuente:Scientific Reports

Extracto: Radiological features such as sequestrum size on CT scan, and MCI values on panoramic radiographs, may aid in differentiating MRONJ in osteoporotic and oncologic patients.

Claves:Clinical assessment, Malignancy, Medication-related osteonecrosis of the jaw (MRONJ), Osteoporosis, Radiographic assessment

Cita:Sci Rep 2024 Apr 16; 14 (1) : 8744.

Autor/es:Shin, Jeong Won (a)
Kim, Jo-Eun (b)

institución:(a) Department of Orthodontics, Institute of Oral Health Science, Ajou University School of Medicine, Suwon, Republic of Korea.
(b) Department of Oral and Maxillofacial Radiology and Dental Research Institute, School of Dentistry, Seoul National University, Seoul, Republic of Korea. noel1st@snu.ac.kr.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1038/s41598-024-59500-x

Preoperative MRI-based endplate quality: a novel tool for predicting cage subsidence after anterior cervical spine surgery.

Preoperative MRI-based endplate quality: a novel tool for predicting cage subsidence after anterior cervical spine surgery.

Fuente:Journal of Orthopaedic Surgery and Research

Extracto: The EBQ method presents itself as a promising and efficient tool for surgeons to assess patients at risk of cage subsidence and osteoporosis prior to cervical spine surgery, utilizing readily accessible patient data.

Claves:Anterior cervical discectomy and fusion, Bone mineral density, Cage subsidence, Cervical spine, Endplate bone quality

Cita:J Orthop Surg Res 2024 Apr 16; 19 (1) : 245.

Autor/es:Tuo, Yuan (a)
Lin, Kaiyuan (b)

institución:(a) Department of Spine Surgery, Honghui Hospital, Xi'an Jiaotong University, No. 76, Nanguo Road, Beilin District, Xi'an, 710054, Shaanxi, China.
(b) Department of Spine Surgery, Honghui Hospital, Xi'an Jiaotong University, No. 76, Nanguo Road, Beilin District, Xi'an, 710054, Shaanxi, China.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1186/s13018-024-04716-w