Textos Completos Autorizados

Osteoporosis y Osteopatías Médicas
SIIC selecciona textos completos de calidad y de reciente publicación en fuentes prestigiosas del mundo indizadas por SIIC Data Bases, capturadas en las mismas colecciones o en diversas bases especializadas.
La creciente cantidad de artículos con Acceso Abierto (Open Access) amplía la oferta de lectura pero a su vez también, entre tanta abundancia, complica al lector en su encuentro con los estudios fundamentales. Para facilitarlo, profesionales biomédicos de SIIC consultan diariamente una profusa cantidad de documentos que nutrirán Textos completos autorizados (TCA).

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Si bien la mayoría de los textos seleccionados corresponden a artículos originales, revisiones y guías, los lectores también encontrarán comentarios, entrevistas, notas periodísticas, cartas a autores u otros textos precursores de debates o aclaratorios.

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Ej.1: Adipokines Ej.2: Adipokines or Musculoskeletal
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Ej.3: Adipokines and Cardiovascular Systems
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Ej.4: Adipokines and Cardiovascular and Systems
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Ej.5: not Cardiovascular Systems
BMC medicine
Selección SIIC: 1 Marzo, 2024
BMC medicine

Neuregulin-1 and ALS19 (ERBB4): at the crossroads of amyotrophic lateral sclerosis and cancer.

Neuregulin-1 and ALS19 (ERBB4): at the crossroads of amyotrophic lateral sclerosis and cancer.

Fuente:Bmc Medicine

Extracto: Common signaling cascades between cancer and ALS may represent novel therapeutic targets for both diseases.

Claves:ALS19, Amyotrophic lateral sclerosis, Cancer, ERBB4, NRG1, Novel targets, Targeted therapy

Cita:BMC Med 2024 Feb 19; 22 (1) : 74.

Autor/es:Adashek, Jacob J (a)
Pandya, Chinmayi (b)

institución:(a) Department of Oncology, The Johns Hopkins Hospital, The Sidney Kimmel Comprehensive Cancer Center, Baltimore, MD, USA. jadashek@westernu.edu.
(b) Center for Personalized Cancer Therapy and Division of Hematology and Oncology, Department of Medicine, UC San Diego Moores Cancer Center, La Jolla, CA, USA.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1186/s12916-024-03293-3

Frontiers in endocrinology
Selección SIIC: 1 Marzo, 2024
Frontiers in endocrinology

Mitochondrial dysfunction and therapeutic perspectives in osteoporosis.

Mitochondrial dysfunction and therapeutic perspectives in osteoporosis.

Fuente:Frontiers in Endocrinology

Extracto: However, from a mitochondrial perspective, the potential for establishing effective and safe therapeutic approaches for osteoporosis appears promising.

Claves:mitochondrial dysfunction, mitochondrial quality control, osteoporosis, oxidative phosphorylation, reactive oxygen species

Cita:Front Endocrinol (Lausanne) 2024; 15 : 1325317.

Autor/es:Liu, Jialing (a)
Gao, Zhonghua (b)

institución:(a) Department of Geriatrics, Liyuan Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
(b) School of Medicine, Ezhou Vocational University, Ezhou, China.

Conflicto:The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3389/fendo.2024.1325317

International journal of nanomedicine
Selección SIIC: 1 Marzo, 2024
International journal of nanomedicine

Bone Targeting Nanoparticles for the Treatment of Osteoporosis.

Bone Targeting Nanoparticles for the Treatment of Osteoporosis.

Fuente:International Journal of Nanomedicine

Extracto: Ongoing research into the development of targeted ligands and nanocarriers will continue to expand the possibilities of OP-targeted therapies into clinical application.

Claves:bone targeting, nanomedicine, osteoporosis therapy

Cita:Int J Nanomedicine 2024; 19 : 1363-1383.

Autor/es:Wen, Caining (a)
Xu, Xiao (b)

institución:(a) Affiliated Hospital of Jining Medical University, Jining Medical University, Jining, Shandong, People's Republic of China.
(b) Affiliated Hospital of Jining Medical University, Jining Medical University, Jining, Shandong, People's Republic of China.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Nueva Zelanda

Sitio web:http://dx.doi.org/10.2147/IJN.S444347

Scientific reports
Selección SIIC: 1 Marzo, 2024
Scientific reports

Circulating osteoprotegerin levels and cardiovascular outcomes in patients with pre-dialysis chronic kidney disease: results from the KNOW-CKD study.

Circulating osteoprotegerin levels and cardiovascular outcomes in patients with pre-dialysis chronic kidney disease: results from the KNOW-CKD study.

Fuente:Scientific Reports

Extracto: In conclusion, elevated circulating OPG levels are associated with adverse cardiovascular outcomes in pre-dialysis CKD patients.

Claves:Biomarker, Chronic kidney disease, Major adverse cardiac event, Osteoprotegerin

Cita:Sci Rep 2024 Feb 19; 14 (1) : 4136.

Autor/es:Suh, Sang Heon (a)
Oh, Tae Ryom (b)

institución:(a) Department of Internal Medicine, Chonnam National University Medical School and Chonnam National University Hospital, 42 Jebongro, Gwangju, 61469, Korea.
(b) Department of Internal Medicine, Chonnam National University Medical School and Chonnam National University Hospital, 42 Jebongro, Gwangju, 61469, Korea.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1038/s41598-024-54335-y

Frontiers in endocrinology
Selección SIIC: 1 Marzo, 2024
Frontiers in endocrinology

A practical guide to the diagnosis and management of osteoporosis in childhood and adolescence.

A practical guide to the diagnosis and management of osteoporosis in childhood and adolescence.

Fuente:Frontiers in Endocrinology

Tipo de trabajo:Revisión

Extracto: The article also provides a sightline to the future, emphasizing the clinical scenarios with the most urgent need for an expanded toolbox of effective osteoporosis agents in childhood.

Claves:bisphosphonate, bone mineral density, children, chronic illness osteoporosis, fractures, osteogenesis imperfecta, osteoporosis, pamidronate

Cita:Front Endocrinol (Lausanne) 2023; 14 : 1266986.

Autor/es:bisphosphonate, bone mineral density, children, chronic illness osteoporosis, fractures, osteogenesis imperfecta, osteoporosis, pamidronate

institución:(a) Department of Pediatrics, Faculty of Medicine, University of Ottawa, Ottawa, ON, Canada.
(b) Department of Pediatrics, Children's Hospital of Eastern Ontario, Ottawa, ON, Canada.

Conflicto:LW declares consultancy to Alexion, Amgen, Ultragenyx, Roche and PTC, and participation in clinical trials with Amgen, Ultragenyx, ReveraGen, and Edgewise, with funds to LW's institution.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3389/fendo.2023.1266986

European review for medical and pharmacological sciences
Selección SIIC: 1 Marzo, 2024
European review for medical and pharmacological sciences

The relationship between vertebral compression rates and systemic inflammatory scores in osteoporotic vertebral fractures.

The relationship between vertebral compression rates and systemic inflammatory scores in osteoporotic vertebral fractures.

Fuente:European Review For Medical and Pharmacological Sciences

Extracto: Although it has been established in the scientific literature that systemic inflammation scores are associated with osteoporotic vertebral fractures, our analysis indicates no statistically significant correlation between the parameters of PPN, PLR, NLR, and SII and the severity of compression fractures in individuals with osteoporotic vertebral fractures. In this study, using systemic inflammation scores as a predictive test for the severity of osteoporotic vertebral fractures does not seem appropriate.

Cita:Eur Rev Med Pharmacol Sci 2024 Feb; 28 (3) : 959-968.

Autor/es:Although it has been established in the scientific literature that systemic inflammation scores are associated with osteoporotic vertebral fractures, our analysis indicates no statistically significant correlation between the parameters of PPN, PLR, NLR, and SII and the severity of compression fractures in individuals with osteoporotic vertebral fractures. In this study, using systemic inflammation scores as a predictive test for the severity of osteoporotic vertebral fractures does not seem appropriate.

institución:Although it has been established in the scientific literature that systemic inflammation scores are associated with osteoporotic vertebral fractures, our analysis indicates no statistically significant correlation between the parameters of PPN, PLR, NLR, and SII and the severity of compression fractures in individuals with osteoporotic vertebral fractures. In this study, using systemic inflammation scores as a predictive test for the severity of osteoporotic vertebral fractures does not seem appropriate.

Formato:Informe impreso

Idioma:Inglés

País de fuente:Italia

Sitio web:http://dx.doi.org/10.26355/eurrev_202402_35333

Selección SIIC: 1 Marzo, 2024

The endogenous oxytocin after manipulative osteopathic treatment in full-term pregnant women.

The endogenous oxytocin after manipulative osteopathic treatment in full-term pregnant women.

Fuente:European Review For Medical and Pharmacological Sciences

Extracto: The results of this study demonstrate that the effectiveness of OMT-increasing endogenous oxytocin is statistically significant in full-term pregnant women. The sensation of well-being found in most women indicates that there has been a predominantly central rather than peripheral oxytocin release after OMT.

Cita:Eur Rev Med Pharmacol Sci 2024 Feb; 28 (3) : 1155-1162.

Autor/es:Ragusa, A (a)
Svelato, A (b)

institución:Ragusa, A (a)
Svelato, A (b)

Formato:Informe impreso

Idioma:Inglés

País de fuente:Italia

Sitio web:http://dx.doi.org/10.26355/eurrev_202402_35354

BMC musculoskeletal disorders
Selección SIIC: 1 Marzo, 2024
BMC musculoskeletal disorders

Opportunistic hand radiographs to screen for low forearm bone mineral density

Opportunistic hand radiographs to screen for low forearm bone mineral density

Fuente:Bmc Musculoskeletal Disorders

Tipo de trabajo:Estudio de cohortes

Extracto: These findings support the expansion of osteoporosis screening to include low-cost hand x-rays, aiming to increase diagnosis and treatment of low forearm BMD and fractures. Proposed next steps include confirming the optimal 2MCP cutoff at scale and integrating automatic 2MCP measurements into PAC systems.

Claves:Bone mineral density, Forearm fractures, Hand x-rays, Osteoporosis

Cita:BMC Musculoskelet Disord 2024 Feb 20; 25 (1) : 159.

Autor/es:O'Mara, Alana (a)
Kerkhof, Faes (b)

institución:(a) Department of Orthopaedic Surgery, Stanford University, Stanford, CA, USA. aeomara@alumni.standford.edu.
(b) Department of Orthopaedic Surgery, Stanford University, Stanford, CA, USA.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1186/s12891-023-07127-w

Selección SIIC: 1 Marzo, 2024

Correlation between bone density, bone metabolism markers with lipid metabolism markers and body mass index.

Correlation between bone density, bone metabolism markers with lipid metabolism markers and body mass index.

Fuente:Bmc Musculoskeletal Disorders

Extracto: HDL-C may have a predictive role in osteoporosis, particularly in women. The likelihood of osteoporosis is lower in individuals with high BMI or hyperlipidemia. Some lipid metabolism markers can be used to predict osteoporosis, and further research is needed.

Claves:Body mass index, Bone mineral density, Bone turnover markers, Lipid profile, Osteoporosis

Cita:BMC Musculoskelet Disord 2024 Feb 20; 25 (1) : 162.

Autor/es:Han, Hao (a)
Li, Ran (b)

institución:(a) Department of Orthopedics, The First Affiliated Hospital of Soochow University, Suzhou, China.
(b) Department of Orthopedics, The First Affiliated Hospital of Soochow University, Suzhou, China.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1186/s12891-024-07284-6

BMJ open quality

Selección SIIC: 1 Marzo, 2024

BMJ open quality

Enhancing safety in the ischaemic and haemorrhagic stroke population: exploring the efficacy of self-releasing chair alarm belts.

Enhancing safety in the ischaemic and haemorrhagic stroke population: exploring the efficacy of self-releasing chair alarm belts.

Fuente:Bmj Open Quality

Extracto: The implementation of self-releasing chair alarm belts significantly reduced falls from chairs among patients who had a stroke in the IRF setting. These findings highlight the effectiveness of this intervention in improving patient safety and fall prevention in IRFs.

Claves:Patient safety, Quality improvement, Rehabilitation

Cita:BMJ Open Qual 2024 Feb 20; 13 (1)

Autor/es:Weppner, Justin (a)
Gee, Alaric (b)

institución:(a) Internal Medicine, Virginia Tech Carilion School of Medicine, Roanoke, Virginia, USA cdvfdrs@gmail.com.
(b) Internal Medicine, Edward Via College of Osteopathic Medicine, Blacksburg, Virginia, USA.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1136/bmjoq-2023-002569

Scientific reports
Selección SIIC: 1 Marzo, 2024
Scientific reports

Validation of phenomenon and cross-sectional investigation of predictors for a post-COVID-19 surge of osteoporosis outpatients in China.

Validation of phenomenon and cross-sectional investigation of predictors for a post-COVID-19 surge of osteoporosis outpatients in China.

Fuente:Scientific Reports

Extracto: This demonstrates resilience of osteoporosis patients to resume regular care despite disruption and stress the substantial backlog of unmet healthcare needs.

Claves:Influencing factor, Internal and external validation, Osteoporosis, Post-COVID-19, Post-lockdown outpatient volume increases

Cita:Sci Rep 2024 Feb 20; 14 (1) : 4230.

Autor/es:Sun, Lei (a)
Zhang, Yuehua (b)

institución:(a) Department of Osteoporosis, Non-Communicable Diseases Research Center, West China-PUMC C.C. Chen Institute of Health, West China School of Public Health and West China Fourth Hospital, Sichuan University, Chengdu, 610041, Sichuan, People's Republic of China.
(b) Department of Osteoporosis, Non-Communicable Diseases Research Center, West China-PUMC C.C. Chen Institute of Health, West China School of Public Health and West China Fourth Hospital, Sichuan University, Chengdu, 610041, Sichuan, People's Republic of China.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1038/s41598-024-54858-4

Selección SIIC: 1 Marzo, 2024

Modified intraocular lens power selection method according to biometric subgroups Eom IOL power calculator.

Modified intraocular lens power selection method according to biometric subgroups Eom IOL power calculator.

Fuente:Scientific Reports

Extracto: In conclusion, the Eom IOL power calculator developed in this study demonstrated similar or slightly better accuracy than the Barrett Universal II and Ladas Super formulas and was superior to the four traditional IOL power calculation formulas.

Claves:Biometry, Calculation, Formula, Intraocular lens, Power

Cita:Sci Rep 2024 Feb 20; 14 (1) : 4228.

Autor/es:Eom, Youngsub (a)
Bae, So Hyeon (b)

institución:(a) Department of Ophthalmology, Korea University Ansan Hospital, 123, Jeokgeum-ro, Danwon-gu, Ansan-si, Gyeonggi-do, 15355, South Korea. hippotate@hanmail.net.
(b) Department of Ophthalmology, Korea University College of Medicine, Seoul, Republic of Korea. hippotate@hanmail.net.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1038/s41598-024-54346-9

Selección SIIC: 1 Marzo, 2024

Association between triglyceride glucose index and total bone mineral density: a cross-sectional study from NHANES 2011-2018.

Association between triglyceride glucose index and total bone mineral density: a cross-sectional study from NHANES 2011-2018.

Fuente:Scientific Reports

Extracto: These findings contributed to understanding the association between TyG, TyG-related indices and total BMD, offering insights for osteoporosis prevention and treatment.

Claves:BMD, Metabolism, NHANES, Osteoporosis, TyG

Cita:Sci Rep 2024 Feb 20; 14 (1) : 4208.

Autor/es:Tian, Ningsheng (a)
Chen, Shuai (b)

institución:(a) Department of Orthopaedics, The Second Affiliated Hospital of Nanjing University of Chinese Medicine, No.23, Nanhu Road, Jianye District, Nanjing, 210017, Jiangsu Province, People's Republic of China.
(b) Department of Orthopaedics, The Second Affiliated Hospital of Nanjing University of Chinese Medicine, No.23, Nanhu Road, Jianye District, Nanjing, 210017, Jiangsu Province, People's Republic of China.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1038/s41598-024-54192-9

Journal of preventive medicine and hygiene

Selección SIIC: 1 Marzo, 2024

Journal of preventive medicine and hygiene

Nurses' knowledge, attitude, and practice regarding osteoporosis prevention and its correlation with their nutritional behaviors.

Nurses' knowledge, attitude, and practice regarding osteoporosis prevention and its correlation with their nutritional behaviors.

Fuente:Journal of Preventive Medicine and Hygiene

Extracto: Given the high levels of knowledge, desirable practices, and in Iranian nurses regarding the prevention of osteoporosis, they can play a significant role in changing KAP and nutritional behaviors of people to prevent this disease. To this end, educational and support programs should be implemented in clinical and community settings to develop a healthy lifestyle in the community.

Claves:Awareness, Belief, Eating habits, Nutritional behaviors, Osteoporosis, Preventive measures

Cita:J Prev Med Hyg 2023 Dec; 64 (4) : E429-E437.

Autor/es:Eslami-Mahmoodabadi, Azam (a)
Foroughameri, Golnaz (b)

institución:(a) Coronary Care Unit, Gharazi Hospital, Social Security Organization, Sirjan, Iran.
(b) Reproductive Health, Family and Population Research Center, Kerman University of Medical Sciences, Kerman, Iran.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Italia

Sitio web:http://dx.doi.org/10.15167/2421-4248/jpmh2023.64.4.2709

PloS one
Selección SIIC: 1 Marzo, 2024
PloS one

Osteoporosis and its associated factors among patients attending Manakamana Hospital, Chitwan, Nepal.

Osteoporosis and its associated factors among patients attending Manakamana Hospital, Chitwan, Nepal.

Fuente:Plos One

Tipo de trabajo:Revisión

Extracto: AND RECOMMENDATIONS: Osteoporosis and osteopenia are prevalent in patients attending in the hospital. Hence, awareness, early screening, and treatment are necessary for the hospital attended patients to enhance their health and, minimize the risk of osteoporosis and the consequences associated with it.

Cita:PLoS One 2024; 19 (2) : e0289517.

Autor/es:Dhakal, Shankar (a)
Sharma, Kalpana (b)

institución:(a) Manakamana Hospital, Bharatpur, Chitwan, Nepal.
(b) Schools of Nursing, Chitwan Medical College, Bharatpur, Chitwan, Nepal.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:EE.UU.

Sitio web:http://dx.doi.org/10.1371/journal.pone.0289517

RMD open
Selección SIIC: 1 Marzo, 2024
RMD open

Rheumatoid arthritis, disease-modifying antirheumatic drugs and risk of major osteoporotic fracture: prospective data from the HUNT Study, Norway.

Rheumatoid arthritis, disease-modifying antirheumatic drugs and risk of major osteoporotic fracture: prospective data from the HUNT Study, Norway.

Fuente:Rmd Open

Extracto: Participants with rheumatoid arthritis had a 40% higher risk of fracture than participants without the disease. A similar fracture risk was observed for conventional synthetic DMARD use, whereas there was weak evidence that the use of biological DMARDs may be associated with a somewhat lower fracture risk.

Claves:Arthritis, Rheumatoid, Biological Therapy, Epidemiology

Cita:RMD Open 2024 Feb 20; 10 (1)

Autor/es:Tronstad, Ingebjørg (a)
Hoff, Mari (b)

institución:(a) HUNT Research Centre, Department of Public Health and Nursing, Norwegian University of Science and Technology, Faculty of Medicine and Health Sciences, Levanger, Trøndelag, Norway ingebjorg.tronstad@ntnu.no.
(b) Department of Medicine and Rehabilitation, Nord-Trøndelag Hospital Trust, Levanger Hospital, Levanger, Trøndelag, Norway.

Conflicto:Competing interests: JH: grants or contracts from any entity; grant from the Liaison Committee for education, research and innovation in Central Norway, grant number 17/38297; payment made to NTNU; payment or honoraria for lectures, presentations, speakers bureaus, manuscript writing or educational events and paid activity as speaker for the Norwegian Physiotherapist Association, presentation March 2023. SAAV: payment or honoraria for... masnoticias.gif

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1136/rmdopen-2023-003919

BMJ open
Selección SIIC: 1 Marzo, 2024
BMJ open

Percutaneous vertebroplasty versus percutaneous kyphoplasty for osteoporotic vertebral compression fractures

Percutaneous vertebroplasty versus percutaneous kyphoplasty for osteoporotic vertebral compression fractures

Fuente:Bmj Open

Tipo de trabajo:Revisión sistemática

Extracto: PROSPERO REGISTRATION NUMBER: CRD42021268141.

Claves:Aging, Bone diseases, ORTHOPAEDIC & TRAUMA SURGERY, Spine

Cita:BMJ Open 2024 Feb 20; 14 (2) : e075225.

Autor/es:Gao, Qingyang (a)
Li, Qiujiang (b)

institución:(a) Department of Plastic and Burn Surgery, West China Hospital, Sichuan University, Chengdu, Sichuan, China.
(b) Department of Orthopedics, Orthopedic Research Institute, West China Hospital, Sichuan University, Chengdu, Sichuan, China.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1136/bmjopen-2023-075225

BMC musculoskeletal disorders
Selección SIIC: 1 Marzo, 2024
BMC musculoskeletal disorders

Improving patients' experiences of diagnosis and treatment of vertebral fracture: co-production of knowledge sharing resources.

Improving patients' experiences of diagnosis and treatment of vertebral fracture: co-production of knowledge sharing resources.

Fuente:Bmc Musculoskeletal Disorders

Tipo de trabajo:Orientaciones y guía

Extracto: The study used robust qualitative methods to co-produce knowledge sharing resources to improve diagnosis. A co-production approach enabled a focus on areas stakeholders thought to be beneficial to timely and accurate diagnosis and treatment. Dissemination of these resources to a range of stakeholders provides potential for substantial reach and spread.

Claves:Co-production, Osteoporosis, Qualitative, Vertebral fractures

Cita:BMC Musculoskelet Disord 2024 Feb 21; 25 (1) : 165.

Autor/es:Bennett, Sarah E (a)
Gooberman-Hill, Rachael (b)

institución:(a) Bristol Medical School, University of Bristol, Bristol, United Kingdom. sarah.bennett@bristol.ac.uk.
(b) Bristol Medical School, University of Bristol, Bristol, United Kingdom.

Conflicto:ZP has undertaken both unpaid and paid, non-promotional consultancy for UCB Pharma. ZP is funded by the National Institute for Health and care Research (NIHR), Clinician Scientist Award (CS-2018-18-ST2-010)/NIHR Academy. SB, RGH, EC, NW and SD declare no competing interests. The views expressed are those of the authors and not necessarily those of the NIHR, NHS or Department for Health... masnoticias.gif

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1186/s12891-024-07281-9

BMC geriatrics
Selección SIIC: 1 Marzo, 2024
BMC geriatrics

The experience of feeling old after a fragility fracture.

The experience of feeling old after a fragility fracture.

Fuente:Bmc Geriatrics

Extracto: Our findings challenge the notion that fractures "happen to old people" and suggest that fractures can make people feel old. Careful consideration of how bone health messages are communicated to patients post-fracture by health care providers is warranted. (Word Count: 248).

Claves:Bone health, Fragility fracture, Patient perspective, Qualitative research, Subjective age

Cita:BMC Geriatr 2024 Feb 22; 24 (1) : 180.

Autor/es:Sale, Joanna E M (a)
Frankel, Lucy (b)

institución:(a) Musculoskeletal Health and Outcomes Research, Li Ka Shing Knowledge Institute, St. Michael's Hospital, Unity Health Toronto, 30 Bond Street, M5B 1W8, Toronto, ON, Canada. Joanna.Sale@unityhealth.to.
(b) Institute of Health Policy, Management and Evaluation University of Toronto, 4th Floor- 155 College Street, M5T 3M6, Toronto, ON, Canada. Joanna.Sale@unityhealth.to.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1186/s12877-024-04769-w

Cells
Selección SIIC: 1 Marzo, 2024
Cells

Novel Glycomimetics Protect against Glycated Low-Density Lipoprotein-Induced Vascular Calcification In Vitro via Attenuation of the RAGE/ERK/CREB Pathway.

Novel Glycomimetics Protect against Glycated Low-Density Lipoprotein-Induced Vascular Calcification In Vitro via Attenuation of the RAGE/ERK/CREB Pathway.

Fuente:Cells

Extracto: In conclusion, these findings demonstrate that novel glycomimetics, C2 and C3 have potent anti-calcification properties in vitro, inhibiting both g-LDL and CLI serum-induced VSMC mineralisation via the inhibition of LDLR, RAGE, CREB and subsequent expression of the downstream osteogenic markers, ALP and OCN.

Claves:critical limb ischemia, glycation, heparan sulphate mimetics, vascular calcification

Cita:Cells 2024 Feb 8; 13 (4)

Autor/es:Sidgwick, Gary P (a)
Weston, Ria (b)

institución:(a) Department of Life Sciences, Manchester Metropolitan University, Manchester M1 5GD, UK.
(b) Department of Life Sciences, Manchester Metropolitan University, Manchester M1 5GD, UK.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3390/cells13040312

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