The associations of IGF2, IGF2R and IGF2BP2 gene polymorphisms with gestational diabetes mellitus: A case-control study.

The associations of IGF2, IGF2R and IGF2BP2 gene polymorphisms with gestational diabetes mellitus: A case-control study.

Fuente:Plos One

Extracto: IGF2 rs680, IGF2R rs416572, IGF2BP2 rs4402960, rs1470579, rs11705701, rs6777038, rs16860234, rs7651090 polymorphisms were not significantly associated with GDM risk in Wuhan, China. Further lager multicenter researches are needed to confirm these results.

Cita:PLoS One 2024; 19 (5) : e0298063.

Autor/es:Li, Wei (a)
She, Lu (b)

institución:(a) Maternal and Child Health Hospital of Hubei Province, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
(b) Xianning Center for Disease Control and Prevention, Xianning, China.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:EE.UU.

Sitio web:http://dx.doi.org/10.1371/journal.pone.0298063

Oral glucose tolerance test clearance in type 2 diabetes patients who underwent remission following intense lifestyle modification: A quasi-experimental study.

Fuente:Plos One

Extracto: Future randomized controlled trials with longer follow-ups may help substantiate our findings.

Cita:PLoS One 2024; 19 (5) : e0302777.

Autor/es:Tripathi, Pramod (a)
Kadam, Nidhi (b)

institución:(a) Department of Research, Freedom from Diabetes Research Foundation, Pune, Maharashtra, India.
(b) Department of Research, Freedom from Diabetes Research Foundation, Pune, Maharashtra, India.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:EE.UU.

Sitio web:http://dx.doi.org/10.1371/journal.pone.0302777

Early feasibility study with an implantable near-infrared spectroscopy sensor for glucose, ketones, lactate and ethanol.

Fuente:Plos One

Tipo de trabajo:Estudio clínico

Extracto: The first implantable multi-biomarker sensor was shown to be well tolerated and produce accurate measurements of glucose, ketones, lactate, and ethanol. TRIAL REGISTRATION: Clinical trial identifier: NCT04782934.

Cita:PLoS One 2024; 19 (5) : e0301041.

Autor/es:De Ridder, Francesca (a)
Braspenning, Rie (b)

institución:(a) Department of Endocrinology-Diabetology-Metabolism, Antwerp University Hospital, Antwerp, Belgium.
(b) Faculty of Medicine & Health Science, Laboratory of Experimental Medicine and Pediatrics, University of Antwerp, Antwerp, Belgium.

Conflicto:I have read the journal’s policy and the authors of this manuscript have the following competing interests: Christophe De Block: consulting fees and honoraria for speaking for Abbott, AstraZeneca, Boehringer-Ingelheim, A. Menarini Diagnostics, Eli Lilly, Medtronic, Novo Nordisk, and Roche, and research support from AstraZeneca, Boehringer-Ingelheim, Indigo Diabetes and Novo Nordisk. Gijs Klarenbeek (Melfin Medical Consulting) has a consultancy agreement... nt with Indigo Diabetes. Danaë Delbeke and Juan Ordonez are employees of Indigo Diabetes NV. All authors read the journal’s policy on competing interests. This does not alter our adherence to PLOS ONE policies on sharing data and materials.

Formato:Informe virtual

Idioma:Inglés

País de fuente:EE.UU.

Sitio web:http://dx.doi.org/10.1371/journal.pone.0301041

Semaglutide combined with empagliflozin vs. monotherapy for non-alcoholic fatty liver disease in type 2 diabetes

Fuente:Plos One

Tipo de trabajo:Estudio clínico aleatorizado

Extracto: TRIAL REGISTRATION: This study has been registered with Chinese Clinical Trial Registry (ChiCTR2300070674).

Cita:PLoS One 2024; 19 (5) : e0302155.

Autor/es:Lin, Yu-Hao (a)
Zhang, Zhi-Jun (b)

institución:(a) Department of Endocrinology, Xiamen Humanity Hospital, Fujian Medical University, Xiamen, Fujian, China.
(b) Department of Endocrinology, Xiamen Humanity Hospital, Fujian Medical University, Xiamen, Fujian, China.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:EE.UU.

Sitio web:http://dx.doi.org/10.1371/journal.pone.0302155

Factors influencing optimal diabetes care and clinical outcomes in Thai patients with type 2 diabetes mellitus: a multilevel modelling analysis.

Factors influencing optimal diabetes care and clinical outcomes in Thai patients with type 2 diabetes mellitus: a multilevel modelling analysis.

Fuente:Bmj Open

Extracto: This highlights the necessity for targeted interventions to bridge urban-suburban care gaps, optimise drug prescriptions and implement comprehensive care strategies for improved glycaemic control, DR prevention and CKD progression mitigation among in Thai patients with T2DM. The value of the clinical target aggregate (ABC) and the process of care aggregate (FAACE) was also conclusively demonstrated.

Claves:diabetic retinopathy, general diabetes, quality in health care

Cita:BMJ Open 2024 May 3; 14 (5) : e079415.

Autor/es:Surawit, Apinya (a)
Pongkunakorn, Tanyaporn (b)

institución:(a) Population Health and Nutrition Research Group, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.
(b) Population Health and Nutrition Research Group, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1136/bmjopen-2023-079415

Utilisation of the health belief model to study the behavioural intentions relating to obesity management among university students: a cross-sectional study.

Fuente:Bmj Open

Extracto: This study underscores the need for tailored health promotion strategies that consider the perceptions and beliefs of people about the management of obesity.

Claves:Body Mass Index, Obesity, PUBLIC HEALTH, Primary Health Care

Cita:BMJ Open 2024 May 3; 14 (5) : e079783.

Autor/es:Albasheer, Osama (a)
Hakami, Nasser (b)

institución:(a) Department of Family and Community Medicine, College of Medicine, Jazan University, Jazan, Saudi Arabia drosama802@gmail.com.
(b) Department of Surgery, College of Medicine, Jazan University, Jazan, Saudi Arabia.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1136/bmjopen-2023-079783

AnnoSpat annotates cell types and quantifies cellular arrangements from spatial proteomics.

AnnoSpat annotates cell types and quantifies cellular arrangements from spatial proteomics.

Fuente:Nature Communications

Extracto: Moreover, the application of AnnoSpat to type 1 diabetic, non-diabetic autoantibody-positive, and non-diabetic organ donor cohorts recapitulates known islet pathobiology and shows differential dynamics of pancreatic polypeptide (PP) cell abundance and CD8(+) T cells infiltration in islets during type 1 diabetes progression.

Cita:Nat Commun 2024 May 3; 15 (1) : 3744.

Autor/es:Mongia, Aanchal (a)
Zohora, Fatema Tuz (b)

institución:(a) Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.
(b) Epigenetics Institute, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1038/s41467-024-47334-0

The reliability of using gingival crevicular blood to measure blood glucose and hba1c levels in the dental setting

The reliability of using gingival crevicular blood to measure blood glucose and hba1c levels in the dental setting

Fuente:Clinical Oral Investigations

Tipo de trabajo:Revisión sistemática

Extracto: Gingival blood could prove to be useful to identify patients with undiagnosed diabetes when the necessary amount of uncontaminated blood is present. However, this technique is limited by the possibility of contamination, prandial status and inaccuracies, so it is unsuited to address the patient's glycemic control accurately.

Claves:Bleeding on probing, Diabetes mellitus, Gingival crevicular blood, Screening

Cita:Clin Oral Investig 2024 May 4; 28 (5) : 299.

Autor/es:Fakheran, Omid (a)
Bencze, Bulcsu (b)

institución:(a) Division of Oral Surgery and Orthodontics, Department of Dentistry and Oral Health, Medical University of Graz, Billrothgasse 4, Graz, 8010, Austria.
(b) Department of Prosthodontics, Semmelweis University, Szentkiralyi utca 47, Budapest, 1088, Hungary.

Conflicto:No potential conflicts of interest relevant to this article were reported by the authors.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Alemania

Sitio web:http://dx.doi.org/10.1007/s00784-024-05685-4

The burden and predictors of 30-day unplanned readmission in patients with acute liver failure: a national representative database study.

The burden and predictors of 30-day unplanned readmission in patients with acute liver failure: a national representative database study.

Fuente:Bmc Gastroenterology

Extracto: Patients with ALF are at relatively high risk of early readmission, which imposes a heavy medical and economic burden on society. We need to increase the emphasis placed on early readmission of patients with ALF and establish clinical strategies for their management.

Claves:ALF, Early readmission, National readmission database, Rehospitalization

Cita:BMC Gastroenterol 2024 May 3; 24 (1) : 153.

Autor/es:Xu, Xianbin (a)
Gong, Kai (b)

institución:(a) State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, National Clinical Research Center for Infectious Diseases, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, 310000, Zhejiang, China.
(b) Department of Infectious Diseases, The Fourth Affiliated Hospital, Zhejiang University School of Medicine, Yiwu, 322000, Zhejiang, China.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1186/s12876-024-03249-0

Type 2 diabetes in the employed population: do rates and trends differ among nine occupational sectors? An analysis using German health insurance claims data.

Type 2 diabetes in the employed population: do rates and trends differ among nine occupational sectors? An analysis using German health insurance claims data.

Fuente:Bmc Public Health

Extracto: The study displayed different vulnerability levels among occupational sectors with respect to T2D prevalence overall and for its rising trend among the younger age group. Specific occupations within the vulnerable sectors need to be focused upon in further research to define specific target groups to which T2D prevention interventions should be tailored.

Claves:Employment, Germany, Health insurance claims data, Occupational sector, Trends, Type 2 diabetes

Cita:BMC Public Health 2024 May 3; 24 (1) : 1231.

Autor/es:Safieddine, Batoul (a)
Grasshoff, Julia (b)

institución:(a) Medical Sociology Unit, Hannover Medical School, Hannover, Germany. Safieddine.Batoul@mh-hannover.de.
(b) Medical Sociology Unit, Hannover Medical School, Hannover, Germany.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1186/s12889-024-18705-5

Pre-hospital glycemia as a biomarker for in-hospital all-cause mortality in diabetic patients - a pilot study.

Pre-hospital glycemia as a biomarker for in-hospital all-cause mortality in diabetic patients - a pilot study.

Fuente:Cardiovascular Diabetology

Tipo de trabajo:Consenso

Extracto: Despite the pilot nature and modest sample size, this study marks the beginning of exploration into personalized glycemic control for hospitalized patients with T2DM. Pre-hospital blood glucose levels and related variables derived from it can serve as biomarkers for all-cause mortality during hospitalization.

Claves:AdaBoost-FAS, Glucose metabolism disorder, Glycemic variability, Machine learning, Type 2 diabetes mellitus

Cita:Cardiovasc Diabetol 2024 May 3; 23 (1) : 153.

Autor/es:Greco, Salvatore (a)
Salatiello, Alessandro (b)

institución:(a) Department of Translational Medicine and for Romagna, University of Ferrara, Via Luigi Borsari, 46, 46 - 44121, Ferrara, Ferrara, Italy.
(b) Medical Department, Azienda Unità Sanitaria Locale di Ferrara, Delta Hospital, Via Valle Oppio, 2, 44023, Lagosanto, Ferrara, Italy.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1186/s12933-024-02245-8

Direct metagenomics investigation of non-surgical hard-to-heal wounds

Direct metagenomics investigation of non-surgical hard-to-heal wounds

Fuente:Annals of Clinical Microbiology and Antimicrobials

Tipo de trabajo:Revisión

Extracto: This study highlighted the benefit of mNGS for time-effective pathogen genome detection. Despite the majority of the included studies investigating only 16 S rDNA, ignoring a part of viral, fungal and parasite colonisation, mNGS detected a large number of bacteria through the included studies. Such technology could be implemented in routine microbiology for hard-to-heal wound microbiota investigation and post-treatment wound colonisation surveillance.

Claves:16S rDNA metagenomics, Non-surgical hard-to-heal wounds, Pathogen genome detection, Shotgun metagenomics, microbial diversity, Wound healing, Wound-colonising microorganisms

Cita:Ann Clin Microbiol Antimicrob 2024 May 3; 23 (1) : 39.

Autor/es:Morsli, Madjid (a)
Salipante, Florian (b)

institución:(a) Department of Microbiology and Hospital Hygiene, VBIC, INSERM U1047, Univ Montpellier, Platform MICRO&BIO, CHU Nîmes, Nîmes, France.
(b) Department of Biostatistics, Clinical Epidemiology, Public Health, and Innovation in Methodology (BESPIM), CHU Nîmes, Nîmes, France.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1186/s12941-024-00698-z

A Deep Auto-Optimized Collaborative Learning (DACL) model for disease prognosis using AI-IoMT systems.

A Deep Auto-Optimized Collaborative Learning (DACL) model for disease prognosis using AI-IoMT systems.

Fuente:Scientific Reports

Extracto: Using some of the well-known benchmarking datasets and performance measures, the proposed DACL's effectiveness and efficiency in identifying diseases is evaluated and compared.

Claves:Artificial Intelligence (AI), Classification.1, Data imputation, Deep Auto-Optimized Collaborative Learning (DACL) model, Disease diagnosis, Internet of Medical Things (IoMT), Optimization

Cita:Sci Rep 2024 May 4; 14 (1) : 10280.

Autor/es:Nandagopal, Malarvizhi (a)
Seerangan, Koteeswaran (b)

institución:(a) Department of CSE, School of Computing, Vel Tech Rangarajan Dr. Sagunthala R&D Institute of Science and Technology, Chennai, Tamil Nadu, 600062, India.
(b) Department of CSE (AI&ML), S.A. Engineering College (Autonomous), Chennai, Tamil Nadu, 600077, India.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1038/s41598-024-59846-2

Role of muscle ultrasound in frailty assessment in older adults with type 2 diabetes mellitus.

Role of muscle ultrasound in frailty assessment in older adults with type 2 diabetes mellitus.

Fuente:Bmc Geriatrics

Extracto: US-derived regional muscle measurements are associated with frailty definitions (in both physical, cumulative deficit, and multidimensional models) in a diabetic geriatric population.

Claves:Diabetes mellitus, Frailty, Muscle ultrasound, Older adults

Cita:BMC Geriatr 2024 May 4; 24 (1) : 397.

Autor/es:Hafızoğlu, Merve (a)
Yıldırım, Hatice Kübra (b)

institución:(a) Department of Internal Medicine, Division of Geriatrics, Hacettepe University Faculty of Medicine, Ankara, Turkey. mervehafizoglu@gmail.com.
(b) Department of Internal Medicine, Hacettepe University Faculty of Medicine, Ankara, Turkey.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1186/s12877-024-05008-y

Differences of skin carotenoids and adherence to the Mediterranean Diet pattern in adults from Southern Italy and Dominican Republic.

Differences of skin carotenoids and adherence to the Mediterranean Diet pattern in adults from Southern Italy and Dominican Republic.

Fuente:Journal of Translational Medicine

Extracto: This study provides the assessment of the adherence to the MD and skin carotenoid content in adults living in Southern Italy and the Dominican Republic, showing a higher MD adherence score and a skin carotenoid content in inhabitants from the Mediterranean region. Our findings highlight the need to globally encourage fruit and vegetable intake, particularly in non-Mediterranean area.

Claves:Carotenoid score, Fruit and vegetable intake, Mediterranean Diet, Veggie Meter®

Cita:J Transl Med 2024 May 4; 22 (1) : 424.

Autor/es:Augimeri, Giuseppina (a)
Soto, Manuel (b)

institución:(a) Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, 87036, Arcavacata di Rende (CS), Italy.
(b) Research Unit, Centro Médico de Diabetes, Obesidad y Especialidades (CEMDOE), Clara María Pardo Street, Santo Domingo, 10135, Distrito Nacional, Dominican Republic.

Conflicto:The authors declare that they have no conflict of interests.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1186/s12967-024-05224-5

Mendelian randomisation and mediation analysis of self-reported walking pace and coronary artery disease.

Mendelian randomisation and mediation analysis of self-reported walking pace and coronary artery disease.

Fuente:Scientific Reports

Extracto: Our findings suggest that interventions that seek to encourage individuals to walk more briskly should lead to protective effects on cardiovascular disease risk.

Cita:Sci Rep 2024 May 1; 14 (1) : 9995.

Autor/es:Timmins, Iain R (a)
Zaccardi, Francesco (b)

institución:(a) Department of Population Health Sciences, University of Leicester, Leicester, UK. iain.timmins@btinternet.com.
(b) Division of Genetics and Epidemiology, Institute of Cancer Research, London, UK. iain.timmins@btinternet.com.

Conflicto:I.R.T. is a full-time AstraZeneca employee. T.Y. has received investigator initiated funding from AstraZeneca. All other authors declare that they do not have any competing interest.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1038/s41598-024-60398-8

Obesity and metabolic syndrome in patients with heart failure with preserved ejection fraction: a cross-sectional analysis of the Veradigm Cardiology Registry.

Obesity and metabolic syndrome in patients with heart failure with preserved ejection fraction: a cross-sectional analysis of the Veradigm Cardiology Registry.

Fuente:Bmc Endocrine Disorders

Extracto: Obesity was common among patients with HFpEF and not always co-occurring with metabolic syndrome. Multivariable analysis suggested that patients with obesity may develop HFpEF in the absence of other driving factors such as cardiovascular disease or metabolic syndrome.

Claves:Heart failure preserved ejection fraction, Left ventricular ejection fraction, Metabolic syndrome, Obesity

Cita:BMC Endocr Disord 2024 May 1; 24 (1) : 59.

Autor/es:Bae, Jay P (a)
Kallenbach, Lee (b)

institución:(a) Eli Lilly and Company, Indianapolis, USA. Bae_jay@lilly.com.
(b) Veradigm, Chicago, USA.

Conflicto:LK, KL, JPW, and MB are employees of Veradigm, which received fees from Eli Lilly and Company related to this work. JPB, DRN, MM are employees of Eli Lilly and Company.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1186/s12902-024-01589-2

Genetic and inflammatory factors underlying gestational diabetes mellitus

Genetic and inflammatory factors underlying gestational diabetes mellitus

Fuente:Frontiers in Endocrinology

Tipo de trabajo:Revisión

Extracto: Ultimately, this review offers insights into the pathophysiological mechanisms of GDM, providing a foundation for developing strategies to mitigate its impact.

Claves:beta-cell dysfunction, genetic factors, genetic variations, gestational diabetes mellitus (GDM), glucose metabolism, inflammatory pathways

Cita:Front Endocrinol (Lausanne) 2024; 15 : 1399694.

Autor/es:Ray, Gyan Watson (a)
Zeng, Qiaoli (b)

institución:(a) Department of Internal Medicine, Shunde Women and Children's Hospital (Maternity and Child Healthcare Hospital of Shunde Foshan), Guangdong Medical University, Foshan, China.
(b) Key Laboratory of Research in Maternal and Child Medicine and Birth Defects, Guangdong Medical University, Foshan, China.

Conflicto:The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3389/fendo.2024.1399694

Comparative Outcomes of Empagliflozin to Dapagliflozin in Patients With Heart Failure.

Comparative Outcomes of Empagliflozin to Dapagliflozin in Patients With Heart Failure.

Fuente:Jama Network Open

Tipo de trabajo:Estudio de cohortes

Extracto: AND RELEVANCE: In this cohort study, patients who initiated empagliflozin were less likely to experience the composite of all-cause mortality or hospitalization compared with patients who started dapagliflozin. Additional studies are needed to confirm these finding.

Cita:JAMA Netw Open 2024 May 1; 7 (5) : e249305.

Autor/es:Modzelewski, Katherine L (a)
Pipilas, Alexandra (b)

institución:(a) Section of Endocrinology, Diabetes, Nutrition and Weight Management, Department of Medicine, Boston University Chobanian and Avedisian School of Medicine, Boston, Massachusetts.
(b) Cardiovascular Medicine, Department of Medicine, Boston University Chobanian and Avedisian School of Medicine, Boston, Massachusetts.

Conflicto:Conflict of Interest Disclosures: Dr Bosch reported receiving grants from the US Department of Defense and the National Heart, Lung, and Blood Institute outside the submitted work. No other disclosures were reported.

Formato:Informe virtual

Idioma:Inglés

País de fuente:EE.UU.

Sitio web:http://dx.doi.org/10.1001/jamanetworkopen.2024.9305

Adverse outcomes in patients hospitalized with pneumonia at age 60 or more: A prospective multi-centric hospital-based study in India.

Adverse outcomes in patients hospitalized with pneumonia at age 60 or more: A prospective multi-centric hospital-based study in India.

Fuente:Plos One

Tipo de trabajo:Guía

Extracto: High ICU admission and 30-day mortality rates were observed among older adults with pneumonia, with a significant proportion linked to influenza and RSV infections. Comprehensive guidelines for CAP prevention and management in older adults are needed, especially with the co-circulation of SARS-CoV-2.

Cita:PLoS One 2024; 19 (5) : e0297452.

Autor/es:Kanungo, Suman (a)
Bhattacharjee, Uttaran (b)

institución:(a) ICMR-National Institute of Cholera and Enteric Diseases, Kolkata, India.
(b) ICMR-National Institute of Cholera and Enteric Diseases, Kolkata, India.

Conflicto:All the authors have declared that no competing interests exist.

Formato:Informe virtual

Idioma:Inglés

País de fuente:EE.UU.

Sitio web:http://dx.doi.org/10.1371/journal.pone.0297452