Mendelian randomisation and mediation analysis of self-reported walking pace and coronary artery disease.

Mendelian randomisation and mediation analysis of self-reported walking pace and coronary artery disease.

Fuente:Scientific Reports

Extracto: Our findings suggest that interventions that seek to encourage individuals to walk more briskly should lead to protective effects on cardiovascular disease risk.

Cita:Sci Rep 2024 May 1; 14 (1) : 9995.

Autor/es:Timmins, Iain R (a)
Zaccardi, Francesco (b)

institución:(a) Department of Population Health Sciences, University of Leicester, Leicester, UK. iain.timmins@btinternet.com.
(b) Division of Genetics and Epidemiology, Institute of Cancer Research, London, UK. iain.timmins@btinternet.com.

Conflicto:I.R.T. is a full-time AstraZeneca employee. T.Y. has received investigator initiated funding from AstraZeneca. All other authors declare that they do not have any competing interest.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1038/s41598-024-60398-8

Obesity and metabolic syndrome in patients with heart failure with preserved ejection fraction: a cross-sectional analysis of the Veradigm Cardiology Registry.

Obesity and metabolic syndrome in patients with heart failure with preserved ejection fraction: a cross-sectional analysis of the Veradigm Cardiology Registry.

Fuente:Bmc Endocrine Disorders

Extracto: Obesity was common among patients with HFpEF and not always co-occurring with metabolic syndrome. Multivariable analysis suggested that patients with obesity may develop HFpEF in the absence of other driving factors such as cardiovascular disease or metabolic syndrome.

Claves:Heart failure preserved ejection fraction, Left ventricular ejection fraction, Metabolic syndrome, Obesity

Cita:BMC Endocr Disord 2024 May 1; 24 (1) : 59.

Autor/es:Bae, Jay P (a)
Kallenbach, Lee (b)

institución:(a) Eli Lilly and Company, Indianapolis, USA. Bae_jay@lilly.com.
(b) Veradigm, Chicago, USA.

Conflicto:LK, KL, JPW, and MB are employees of Veradigm, which received fees from Eli Lilly and Company related to this work. JPB, DRN, MM are employees of Eli Lilly and Company.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1186/s12902-024-01589-2

Genetic and inflammatory factors underlying gestational diabetes mellitus

Genetic and inflammatory factors underlying gestational diabetes mellitus

Fuente:Frontiers in Endocrinology

Tipo de trabajo:Revisión

Extracto: Ultimately, this review offers insights into the pathophysiological mechanisms of GDM, providing a foundation for developing strategies to mitigate its impact.

Claves:beta-cell dysfunction, genetic factors, genetic variations, gestational diabetes mellitus (GDM), glucose metabolism, inflammatory pathways

Cita:Front Endocrinol (Lausanne) 2024; 15 : 1399694.

Autor/es:Ray, Gyan Watson (a)
Zeng, Qiaoli (b)

institución:(a) Department of Internal Medicine, Shunde Women and Children's Hospital (Maternity and Child Healthcare Hospital of Shunde Foshan), Guangdong Medical University, Foshan, China.
(b) Key Laboratory of Research in Maternal and Child Medicine and Birth Defects, Guangdong Medical University, Foshan, China.

Conflicto:The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3389/fendo.2024.1399694

Comparative Outcomes of Empagliflozin to Dapagliflozin in Patients With Heart Failure.

Comparative Outcomes of Empagliflozin to Dapagliflozin in Patients With Heart Failure.

Fuente:Jama Network Open

Tipo de trabajo:Estudio de cohortes

Extracto: AND RELEVANCE: In this cohort study, patients who initiated empagliflozin were less likely to experience the composite of all-cause mortality or hospitalization compared with patients who started dapagliflozin. Additional studies are needed to confirm these finding.

Cita:JAMA Netw Open 2024 May 1; 7 (5) : e249305.

Autor/es:Modzelewski, Katherine L (a)
Pipilas, Alexandra (b)

institución:(a) Section of Endocrinology, Diabetes, Nutrition and Weight Management, Department of Medicine, Boston University Chobanian and Avedisian School of Medicine, Boston, Massachusetts.
(b) Cardiovascular Medicine, Department of Medicine, Boston University Chobanian and Avedisian School of Medicine, Boston, Massachusetts.

Conflicto:Conflict of Interest Disclosures: Dr Bosch reported receiving grants from the US Department of Defense and the National Heart, Lung, and Blood Institute outside the submitted work. No other disclosures were reported.

Formato:Informe virtual

Idioma:Inglés

País de fuente:EE.UU.

Sitio web:http://dx.doi.org/10.1001/jamanetworkopen.2024.9305

Adverse outcomes in patients hospitalized with pneumonia at age 60 or more: A prospective multi-centric hospital-based study in India.

Adverse outcomes in patients hospitalized with pneumonia at age 60 or more: A prospective multi-centric hospital-based study in India.

Fuente:Plos One

Tipo de trabajo:Guía

Extracto: High ICU admission and 30-day mortality rates were observed among older adults with pneumonia, with a significant proportion linked to influenza and RSV infections. Comprehensive guidelines for CAP prevention and management in older adults are needed, especially with the co-circulation of SARS-CoV-2.

Cita:PLoS One 2024; 19 (5) : e0297452.

Autor/es:Kanungo, Suman (a)
Bhattacharjee, Uttaran (b)

institución:(a) ICMR-National Institute of Cholera and Enteric Diseases, Kolkata, India.
(b) ICMR-National Institute of Cholera and Enteric Diseases, Kolkata, India.

Conflicto:All the authors have declared that no competing interests exist.

Formato:Informe virtual

Idioma:Inglés

País de fuente:EE.UU.

Sitio web:http://dx.doi.org/10.1371/journal.pone.0297452

Renal and major clinical outcomes and their determinants after nephrectomy in patients with pre-existing chronic kidney disease

Fuente:Plos One

Tipo de trabajo:Estudio de cohortes

Extracto: Postoperative AKI after PN or RN was the major independent determinant of worse outcomes (CKD progression, MACE, or death) one year after surgery.

Cita:PLoS One 2024; 19 (5) : e0300367.

Autor/es:Schleef, Maxime (a)
Roy, Pascal (b)

institución:(a) Lyon University, CarMeN laboratory, IRIS team, INSERM, INRAE, Université Claude Bernard Lyon-1, Bron, France.
(b) Department of intensive care medicine, Hôpital Edouard Herriot, Hospices Civils de Lyon, Lyon, France.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:EE.UU.

Sitio web:http://dx.doi.org/10.1371/journal.pone.0300367

The impact of lifestyle, measured with the HLPCQ questionnaire on the prevalence of metabolic syndrome in Poland: a multicenter study.

The impact of lifestyle, measured with the HLPCQ questionnaire on the prevalence of metabolic syndrome in Poland: a multicenter study.

Fuente:Scientific Reports

Extracto: Results obtained in our study from analysis of HLPCQ show that screening for metabolic syndrome should be preceded by prevention based on regular physical activity and proper eating habits.

Claves:Epidemiology of the metabolic syndrome, HLPCQ, Life style, Metabolic syndrome, Obesity

Cita:Sci Rep 2024 May 2; 14 (1) : 10070.

Autor/es:Babicki, Mateusz (a)
Kłoda, Karolina (b)

institución:(a) Department of Family Medicine, Wroclaw Medical University, 50-367, Wrocław, Poland. ma.babicki@gmail.com.
(b) Department of Family Medicine, Wroclaw Medical University, Ul. Syrokomli 1, 51-141, Wroclaw, Poland. ma.babicki@gmail.com.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1038/s41598-024-60866-1

Association between biological aging and diabetic retinopathy.

Fuente:Scientific Reports

Extracto: Our findings underscored the importance of timely anti-aging interventions for preventing DR.

Claves:Biological aging, Chronological age, Diabetic retinopathy, NHANES

Cita:Sci Rep 2024 May 2; 14 (1) : 10123.

Autor/es:Tang, Haoxian (a)
Luo, Nan (b)

institución:(a) Shantou University Medical College, Shantou, Guangdong, China.
(b) Department of Cardiology, The First Affiliated Hospital of Shantou University Medical College, Shantou, Guangdong, China.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1038/s41598-024-60913-x

Cardiac evaluation in amiodarone-induced thyroid dysfunction with suspected cardiac ischemia?

Cardiac evaluation in amiodarone-induced thyroid dysfunction with suspected cardiac ischemia?

Fuente:Journal of Medical Case Reports

Tipo de trabajo:Revisión

Extracto: We discuss here cardiac abnormalities in patients with AIT, which may be due to relative ischemia secondary to increased metabolic demand during hyperthyroidism. Improvement of cardiac complications is expected through an optimal AIT therapy including medical therapy as the primary approach and, when necessary, thyroidectomy. Cardiac investigations in the context of AIT should be carefully considered and may not justify delaying other crucial interventions. If considered mandatory, diagnostic procedures such as coronary angiography should be preferred to functional testing.

Claves:Amiodarone, Cardiac ischemia, Case report, Hyperthyroidism, Thyroidectomy

Cita:J Med Case Rep 2024 May 2; 18 (1) : 235.

Autor/es:Aubry, Yoann (a)
Dosch, Michel (b)

institución:(a) Clinic of Endocrinology, Diabetes and Metabolism, Hospital Delémont, Hôpital du Jura, Faubourg Des Capucins 30, 2800, Delémont, Switzerland. Yoann.Aubry@h-ju.ch.
(b) Clinic of Endocrinology, Diabetes and Metabolism, University Hospital Basel, Basel, Switzerland. Yoann.Aubry@h-ju.ch.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1186/s13256-024-04552-w

Exploring exercise-driven exerkines: unraveling the regulation of metabolism and inflammation.

Exploring exercise-driven exerkines: unraveling the regulation of metabolism and inflammation.

Fuente:Peerj

Extracto: Moreover, a comprehensive overview and analysis of recent advancements are provided in this review, in addition to predicting future applications used as a potential biomarker or therapeutic target to benefit patients with chronic diseases.

Claves:Chronic diseases, Exercise factors, Exerkines, Inflammation, Metabolism

Cita:PeerJ 2024; 12 : e17267.

Autor/es:Zhou, Nihong (a)
Gong, Lijing (b)

institución:(a) Key Laboratory of Physical Fitness and Exercise, Ministry of Education, Beijing Sport University, Beijing, China.
(b) School of Sport Science, Beijing Sport University, Beijing, China.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:EE.UU.

Sitio web:http://dx.doi.org/10.7717/peerj.17267

Clinical Characteristics of EGPA Patients in Comparison to GPA Subgroup with Increased Blood Eosinophilia from POLVAS Registry.

Clinical Characteristics of EGPA Patients in Comparison to GPA Subgroup with Increased Blood Eosinophilia from POLVAS Registry.

Fuente:Journal of Immunology Research

Extracto: Cardiovascular symptoms were more prevalent in the ANCA-negative subset than in the MPO-ANCA-positive one. Since EGPA and GPE HE share similarities in clinics, diagnostic misleading may result in an inappropriate therapeutic approach. Further studies are needed to optimize their differentiation and tailored therapy, including biologics.

Cita:J Immunol Res 2024; 2024 : 4283928.

Autor/es:Drynda, Anna (a)
Padjas, Agnieszka (b)

institución:(a) Students' Scientific Group of Immune Diseases and Hypercoagulation, Jagiellonian University Medical College, Cracow, Poland.
(b) 2nd Department of Internal Medicine, Jagiellonian University Medical College, Cracow, Poland.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Egipto

Sitio web:http://dx.doi.org/10.1155/2024/4283928

Positive association between blood ethylene oxide levels and metabolic syndrome: NHANES 2013-2020.

Positive association between blood ethylene oxide levels and metabolic syndrome: NHANES 2013-2020.

Fuente:Frontiers in Endocrinology

Extracto: This study indicates a linear correlation between MetS and HbEO, with MetS risk escalating as HbEO levels increase. The prevalence of MetS varies depending on BMI, age and gender, and these factors can also influence MetS prevalence when exposed to EO.

Claves:NHANES, epidemiology, ethylene oxide, inflammation, metabolic syndrome

Cita:Front Endocrinol (Lausanne) 2024; 15 : 1365658.

Autor/es:Zhou, Chunqi (a)
Wang, Senlin (b)

institución:(a) College of Medicine, Southwest Jiaotong University, Chengdu, Sichuan, China.
(b) Department of General Surgery, Affiliated Hospital of Southwest Jiaotong University, College of Medicine, Southwest Jiaotong University, Chengdu, Sichuan, China.

Conflicto:The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3389/fendo.2024.1365658

Effects of temporal changes in resting heart rate on future diabetes-related outcomes.

Fuente:Frontiers in Endocrinology

Extracto: Changes in RHR had predictive value for long-term clinical events in diabetic populations. Individuals with significantly elevated RHR over a particular period of time showed an increased risk of adverse events.

Claves:change, clinical outcomes, long-term, resting heart rate, type 2 diabetes mellitus

Cita:Front Endocrinol (Lausanne) 2024; 15 : 1385143.

Autor/es:Gao, Lu (a)
Wang, Guo-Hong (b)

institución:(a) Department of Geriatrics, Beijing Tongren Hospital, Capital Medical University, Beijing, China.
(b) Department of Geriatrics, Beijing Tongren Hospital, Capital Medical University, Beijing, China.

Conflicto:The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3389/fendo.2024.1385143

Temporal change in multimorbidity prevalence, clustering patterns, and the association with mortality: findings from the China Kadoorie Biobank study in Jiangsu Province.

Temporal change in multimorbidity prevalence, clustering patterns, and the association with mortality: findings from the China Kadoorie Biobank study in Jiangsu Province.

Fuente:Frontiers in Public Health

Extracto: The prevalence of multimorbidity has increased substantially over the past decade. This study has revealed that cardiometabolic multimorbidity and respiratory multimorbidity have significantly increased mortality rates. These findings indicate the need to consider high-risk populations and to provide local evidence for intervention strategies and health management in economically developed regions.

Claves:cluster analysis, cohort study, mortality, multimorbidity, prevalence

Cita:Front Public Health 2024; 12 : 1389635.

Autor/es:Yu, Hao (a)
Tao, Ran (b)

institución:(a) Department of Epidemiology and Biostatistics, School of Public Health, Peking University, Beijing, China.
(b) Department of Noncommunicable Chronic Disease and Prevention, Jiangsu Provincial Center for Disease Control and Prevention, Nanjing, China.

Conflicto:The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3389/fpubh.2024.1389635

Exploring the intersection of obesity and gender in COVID-19 outcomes in hospitalized Mexican patients: a comparative analysis of risk profiles using unsupervised machine learning.

Fuente:Frontiers in Public Health

Tipo de trabajo:Consenso

Extracto: Our analysis emphasizes the complex interplay between obesity, gender, and health outcomes in COVID-19 hospitalizations. The identified risk profiles highlight the need for personalized treatment strategies for COVID-19 patients and can assist in planning for patterns of deterioration in future waves of SARS-CoV-2 virus transmission. This research underscores the importance of tackling obesity as a major public health concern, given its interplay with many other health conditions, including infectious diseases such as COVID-19.

Claves:COVID-19, consensus clustering, obesity, risk factor, risk profile discovery, unsupervised machine learning

Cita:Front Public Health 2024; 12 : 1337432.

Autor/es:Nezhadmoghadam, Fahimeh (a)
Tamez-Peña, José Gerardo (b)

institución:(a) Tecnologico de Monterrey, The Institute for Obesity Research, Monterrey, Mexico.
(b) Tecnologico de Monterrey, Escuela de Medicina y Ciencias de la Salud, Monterrey, Mexico.

Conflicto:The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3389/fpubh.2024.1337432

Pediatric hypertension as an early manifestation of cardiovascular disease in children.

Pediatric hypertension as an early manifestation of cardiovascular disease in children.

Fuente:Jornal Brasileiro de Nefrologia

Extracto: Pharmacological therapy should be initiated in cases of symptomatic AH, AH secondary to chronic kidney disease or diabetes mellitus, presence of target organ lesions, stage 2 AH with no modifiable cause and resistant AH unresponsive to lifestyle changes.

Cita:J Bras Nefrol 2024; 46 (4) : e20230159.

Autor/es:Koch, Vera Hermina Kalika (a)
Furusawa, Erika Arai (b)

institución:(a) Universidade de São Paulo, Faculdade de Medicina, Departamento de Pediatria, São Paulo, SP, Brazil.
(b) Universidade de São Paulo, Faculdade de Medicina, São Paulo, SP, Brazil.

Formato:Informe virtual

Idioma:eng, por

País de fuente:Brasil

Sitio web:http://dx.doi.org/10.1590/2175-8239-JBN-2023-0159en

Irregular Cycles, Ovulatory Disorders, and Cardiometabolic Conditions in a US-Based Digital Cohort.

Irregular Cycles, Ovulatory Disorders, and Cardiometabolic Conditions in a US-Based Digital Cohort.

Fuente:Jama Network Open

Extracto: AND RELEVANCE: These findings suggest that PCOS and irregular cycles may be independent markers for cardiometabolic conditions. Early screening and intervention among individuals with irregular menstrual cycles may be beneficial.

Cita:JAMA Netw Open 2024 May 1; 7 (5) : e249657.

Autor/es:Wang, Zifan (a)
Jukic, Anne Marie Z (b)

institución:(a) Department of Environmental Health, Harvard T.H. Chan School of Public Health, Boston, Massachusetts.
(b) Epidemiology Branch, Division of Intramural Research, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, Durham, North Carolina.

Conflicto:Conflict of Interest Disclosures: Dr Coull reported receiving grants from the National Institutes of Health outside the submitted work. Dr Hauser reported receiving grants from the National Institutes of Health outside the submitted work. Dr Mahalingaiah reported receiving grants from the National Institutes of Health outside the submitted work. Dr Curry reported owning stocks in Apple. Mr Fischer-Colbrie reported owning... stocks in Apple. No other disclosures were reported.

Formato:Informe virtual

Idioma:Inglés

País de fuente:EE.UU.

Sitio web:http://dx.doi.org/10.1001/jamanetworkopen.2024.9657

Insulin sensitivity estimates and their longitudinal association with coronary artery disease in type 1 diabetes. Does it matter?

Insulin sensitivity estimates and their longitudinal association with coronary artery disease in type 1 diabetes. Does it matter?

Fuente:Cardiovascular Diabetology

Extracto: In type 1 diabetes, estimated glucose disposal rates are associated with subsequent coronary artery disease, modulated by kidney disease severity. Future research is merited regarding the clinical usefulness of estimating the glucose disposal rate as a coronary artery disease risk factor and potential therapeutic target.

Claves:Cardiovascular diseases, Coronary artery disease, Insulin resistance, Kidney disease, Type 1 diabetes mellitus

Cita:Cardiovasc Diabetol 2024 May 3; 23 (1) : 152.

Autor/es:Mutter, Stefan (a)
Parente, Erika B (b)

institución:(a) Folkhälsan Institute of Genetics, Folkhälsan Research Center, Biomedicum Helsinki, Haartmaninkatu 8, 00290, Helsinki, Finland.
(b) Department of Nephrology, University of Helsinki and Helsinki University Hospital, Haartmaninkatu 4, 00290, Helsinki, Finland.

Conflicto:S.M. reports receiving lecture honoraria from Encore Medical Education. E.B.P. reports receiving lecture honorariums from Sanofi and Astra Zeneca. P.H.G. reports receiving lecture honorariums from Astellas, AstraZeneca, Bayer, Boehringer Ingelheim, Eli Lilly, Elo Water, Medscape, MSD, Mundipharma, Novo Nordisk, PeerVoice, Sanofi, Sciarc, and being an advisory board member of AbbVie, Astellas, AstraZeneca, Bayer, Boehringer Ingelheim, Eli Lilly, Medscape, MSD, Mundipharma,... Nestlé, Novo Nordisk, and Sanofi. All other authors declare no conflict of interest.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1186/s12933-024-02234-x

Association of non-insulin-based insulin resistance indices with disease severity and adverse outcome in idiopathic pulmonary arterial hypertension

Fuente:Cardiovascular Diabetology

Tipo de trabajo:Estudio de cohortes

Extracto: IR is associated with the severity and long-term prognosis of IPAH. TyG-BMI and METS-IR can independently predict clinical worsening events, while METS-IR also provide incremental predictive performance beyond the ESC risk stratification.

Claves:Idiopathic pulmonary arterial hypertension, Insulin resistance, Metabolic score for insulin resistance, Prognosis, Severity

Cita:Cardiovasc Diabetol 2024 May 3; 23 (1) : 154.

Autor/es:Zhang, Sicheng (a)
Gao, Luyang (b)

institución:(a) Center for Respiratory and Pulmonary Vascular Diseases, National Center for Cardiovascular Diseases, Fuwai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, No. 167, Beilishi Road, Beijing, 100037, Xicheng, China.
(b) Center for Respiratory and Pulmonary Vascular Diseases, National Center for Cardiovascular Diseases, Fuwai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, No. 167, Beilishi Road, Beijing, 100037, Xicheng, China.

Conflicto:The authors declared that they have no competing of interest.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1186/s12933-024-02236-9

Factors associated with non-fatal heart failure and atrial fibrillation or flutter within the first 30 days post COPD exacerbation: a nested case-control study.

Factors associated with non-fatal heart failure and atrial fibrillation or flutter within the first 30 days post COPD exacerbation: a nested case-control study.

Fuente:Bmc Pulmonary Medicine

Extracto: Cardiopulmonary factors were associated with hospitalization for HF in the 30 days following a COPD exacerbation, while only cardiovascular-related factors and exacerbation severity were associated with AF hospitalization. Understanding factors will help target people for prevention.

Claves:Arrhythmia, Atrial Fibrillation, Cardiovascular Disease, Chronic Obstructive Pulmonary Disease Exacerbations, Electronic Health Records, Epidemiology, Flutter, Heart Failure

Cita:BMC Pulm Med 2024 May 4; 24 (1) : 221.

Autor/es:Graul, Emily L (a)
Nordon, Clementine (b)

institución:(a) School of Public Health, Imperial College London, 86 Wood Lane, London, W12 0BZ, UK.
(b) Biopharmaceuticals Medical, AstraZeneca, Academy House, 136 Hills Rd, Cambridge, CB2 8PA, UK.

Conflicto:JQ reports grants from GlaxoSmithKline, Health Data Research UK, MRC, Asthma+Lung UK, Bayer, BI, AZ and Chiesi, outside this work and AZ for the conduct of this study. JQ has received personal fees for advisory board participation, consultancy or speaking fees from GlaxoSmithKline, Evidera, AstraZeneca, and Insmed. CN, KR, and SM are employees of AZ and hold stock and/or options... in the company. HW reports grants from Health Data Research UK outside the submitted work. EG, CK, AI, and MA have nothing to disclose.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1186/s12890-024-03035-4